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Neutrofiele granulocyt - Wikipedia
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Beschikbaar in 52 talen" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-52" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">52 talen</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AE%D9%84%D9%8A%D8%A9_%D9%85%D8%AA%D8%B9%D8%A7%D8%AF%D9%84%D8%A9" title="خلية متعادلة – Arabisch" lang="ar" hreflang="ar" data-title="خلية متعادلة" data-language-autonym="العربية" data-language-local-name="Arabisch" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%9D%D0%B5%D1%83%D1%82%D1%80%D0%BE%D1%84%D0%B8%D0%BB%D0%B5%D0%BD_%D0%B3%D1%80%D0%B0%D0%BD%D1%83%D0%BB%D0%BE%D1%86%D0%B8%D1%82" title="Неутрофилен гранулоцит – Bulgaars" lang="bg" hreflang="bg" data-title="Неутрофилен гранулоцит" data-language-autonym="Български" data-language-local-name="Bulgaars" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%A8%E0%A6%BF%E0%A6%89%E0%A6%9F%E0%A7%8D%E0%A6%B0%E0%A7%8B%E0%A6%AB%E0%A6%BF%E0%A6%B2" title="নিউট্রোফিল – Bengaals" lang="bn" hreflang="bn" data-title="নিউট্রোফিল" data-language-autonym="বাংলা" data-language-local-name="Bengaals" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Neutrofilni_granulociti" title="Neutrofilni granulociti – Bosnisch" lang="bs" hreflang="bs" data-title="Neutrofilni granulociti" data-language-autonym="Bosanski" data-language-local-name="Bosnisch" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Neutr%C3%B2fil" title="Neutròfil – Catalaans" lang="ca" hreflang="ca" data-title="Neutròfil" data-language-autonym="Català" data-language-local-name="Catalaans" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Neutrofiln%C3%AD_granulocyt" title="Neutrofilní granulocyt – Tsjechisch" lang="cs" hreflang="cs" data-title="Neutrofilní granulocyt" data-language-autonym="Čeština" data-language-local-name="Tsjechisch" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Neutrophiler_Granulozyt" title="Neutrophiler Granulozyt – Duits" lang="de" hreflang="de" data-title="Neutrophiler Granulozyt" data-language-autonym="Deutsch" data-language-local-name="Duits" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-dv mw-list-item"><a href="https://dv.wikipedia.org/wiki/%DE%82%DE%AB%DE%93%DE%B0%DE%83%DE%A6%DE%8A%DE%A8%DE%8D%DE%B0" title="ނޫޓްރަފިލް – Divehi" lang="dv" hreflang="dv" data-title="ނޫޓްރަފިލް" data-language-autonym="ދިވެހިބަސް" data-language-local-name="Divehi" class="interlanguage-link-target"><span>ދިވެހިބަސް</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%9F%CF%85%CE%B4%CE%B5%CF%84%CE%B5%CF%81%CF%8C%CF%86%CE%B9%CE%BB%CE%B1_-_%CF%80%CE%BF%CE%BB%CF%85%CE%BC%CE%BF%CF%81%CF%86%CE%BF%CF%80%CF%8D%CF%81%CE%B7%CE%BD%CE%B1" title="Ουδετερόφιλα - πολυμορφοπύρηνα – Grieks" lang="el" hreflang="el" data-title="Ουδετερόφιλα - πολυμορφοπύρηνα" data-language-autonym="Ελληνικά" data-language-local-name="Grieks" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Neutrophil" title="Neutrophil – Engels" lang="en" hreflang="en" data-title="Neutrophil" data-language-autonym="English" data-language-local-name="Engels" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Neutr%C3%B3filo" title="Neutrófilo – Spaans" lang="es" hreflang="es" data-title="Neutrófilo" data-language-autonym="Español" data-language-local-name="Spaans" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Neutrofiil" title="Neutrofiil – Estisch" lang="et" hreflang="et" data-title="Neutrofiil" data-language-autonym="Eesti" data-language-local-name="Estisch" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Neutrofilo" title="Neutrofilo – Baskisch" lang="eu" hreflang="eu" data-title="Neutrofilo" data-language-autonym="Euskara" data-language-local-name="Baskisch" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%86%D9%88%D8%AA%D8%B1%D9%88%D9%81%DB%8C%D9%84" title="نوتروفیل – Perzisch" lang="fa" hreflang="fa" data-title="نوتروفیل" data-language-autonym="فارسی" data-language-local-name="Perzisch" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Neutrofiili" title="Neutrofiili – Fins" lang="fi" hreflang="fi" data-title="Neutrofiili" data-language-autonym="Suomi" data-language-local-name="Fins" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Granulocyte_neutrophile" title="Granulocyte neutrophile – Frans" lang="fr" hreflang="fr" data-title="Granulocyte neutrophile" data-language-autonym="Français" data-language-local-name="Frans" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Neutr%C3%B3filo" title="Neutrófilo – Galicisch" lang="gl" hreflang="gl" data-title="Neutrófilo" data-language-autonym="Galego" data-language-local-name="Galicisch" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-hak mw-list-item"><a href="https://hak.wikipedia.org/wiki/Ch%C3%BBng-sin_pha%CC%8Dk-hiet-khi%C3%B9" title="Chûng-sin pha̍k-hiet-khiù – Hakka" lang="hak" hreflang="hak" data-title="Chûng-sin pha̍k-hiet-khiù" data-language-autonym="客家語 / Hak-kâ-ngî" data-language-local-name="Hakka" class="interlanguage-link-target"><span>客家語 / Hak-kâ-ngî</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%A0%D7%95%D7%99%D7%98%D7%A8%D7%95%D7%A4%D7%99%D7%9C" title="נויטרופיל – Hebreeuws" lang="he" hreflang="he" data-title="נויטרופיל" data-language-autonym="עברית" data-language-local-name="Hebreeuws" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Neutrofil_granulocita" title="Neutrofil granulocita – Hongaars" lang="hu" hreflang="hu" data-title="Neutrofil granulocita" data-language-autonym="Magyar" data-language-local-name="Hongaars" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%86%D5%A5%D5%B5%D5%BF%D6%80%D5%B8%D6%86%D5%AB%D5%AC%D5%A1%D5%B5%D5%AB%D5%B6_%D5%A3%D6%80%D5%A1%D5%B6%D5%B8%D6%82%D5%AC%D5%B8%D6%81%D5%AB%D5%BF%D5%B6%D5%A5%D6%80" title="Նեյտրոֆիլային գրանուլոցիտներ – Armeens" lang="hy" hreflang="hy" data-title="Նեյտրոֆիլային գրանուլոցիտներ" data-language-autonym="Հայերեն" data-language-local-name="Armeens" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Neutrofil" title="Neutrofil – Indonesisch" lang="id" hreflang="id" data-title="Neutrofil" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesisch" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Granulocita_neutrofilo" title="Granulocita neutrofilo – Italiaans" lang="it" hreflang="it" data-title="Granulocita neutrofilo" data-language-autonym="Italiano" data-language-local-name="Italiaans" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E5%A5%BD%E4%B8%AD%E7%90%83" title="好中球 – Japans" lang="ja" hreflang="ja" data-title="好中球" data-language-autonym="日本語" data-language-local-name="Japans" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-jv mw-list-item"><a href="https://jv.wikipedia.org/wiki/Neutrofil" title="Neutrofil – Javaans" lang="jv" hreflang="jv" data-title="Neutrofil" data-language-autonym="Jawa" data-language-local-name="Javaans" class="interlanguage-link-target"><span>Jawa</span></a></li><li class="interlanguage-link interwiki-ka mw-list-item"><a href="https://ka.wikipedia.org/wiki/%E1%83%9C%E1%83%94%E1%83%98%E1%83%A2%E1%83%A0%E1%83%9D%E1%83%A4%E1%83%98%E1%83%9A%E1%83%94%E1%83%91%E1%83%98" title="ნეიტროფილები – Georgisch" lang="ka" hreflang="ka" data-title="ნეიტროფილები" data-language-autonym="ქართული" data-language-local-name="Georgisch" class="interlanguage-link-target"><span>ქართული</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%9D%D0%B5%D0%B9%D1%82%D1%80%D0%BE%D1%84%D0%B8%D0%BB%D0%B4%D1%96_%D0%BB%D0%B5%D0%B9%D0%BA%D0%BE%D1%86%D0%B8%D1%82%D1%82%D0%B5%D1%80" title="Нейтрофилді лейкоциттер – Kazachs" lang="kk" hreflang="kk" data-title="Нейтрофилді лейкоциттер" data-language-autonym="Қазақша" data-language-local-name="Kazachs" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%ED%98%B8%EC%A4%91%EA%B5%AC" title="호중구 – Koreaans" lang="ko" hreflang="ko" data-title="호중구" data-language-autonym="한국어" data-language-local-name="Koreaans" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/N%C3%AAtrof%C3%AEl" title="Nêtrofîl – Koerdisch" lang="ku" hreflang="ku" data-title="Nêtrofîl" data-language-autonym="Kurdî" data-language-local-name="Koerdisch" class="interlanguage-link-target"><span>Kurdî</span></a></li><li class="interlanguage-link interwiki-lmo mw-list-item"><a href="https://lmo.wikipedia.org/wiki/Neutrofil" title="Neutrofil – Lombardisch" lang="lmo" hreflang="lmo" data-title="Neutrofil" data-language-autonym="Lombard" data-language-local-name="Lombardisch" class="interlanguage-link-target"><span>Lombard</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Neutrofilas" title="Neutrofilas – Litouws" lang="lt" hreflang="lt" data-title="Neutrofilas" data-language-autonym="Lietuvių" data-language-local-name="Litouws" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Neitrofilie_leikoc%C4%ABti" title="Neitrofilie leikocīti – Lets" lang="lv" hreflang="lv" data-title="Neitrofilie leikocīti" data-language-autonym="Latviešu" data-language-local-name="Lets" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%9D%D0%B5%D1%83%D1%82%D1%80%D0%BE%D1%84%D0%B8%D0%BB%D0%B5%D0%BD_%D0%B3%D1%80%D0%B0%D0%BD%D1%83%D0%BB%D0%BE%D1%86%D0%B8%D1%82" title="Неутрофилен гранулоцит – Macedonisch" lang="mk" hreflang="mk" data-title="Неутрофилен гранулоцит" data-language-autonym="Македонски" data-language-local-name="Macedonisch" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Neutrofil" title="Neutrofil – Maleis" lang="ms" hreflang="ms" data-title="Neutrofil" data-language-autonym="Bahasa Melayu" data-language-local-name="Maleis" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/N%C3%B8ytrofile_granulocytter" title="Nøytrofile granulocytter – Noors - Bokmål" lang="nb" hreflang="nb" data-title="Nøytrofile granulocytter" data-language-autonym="Norsk bokmål" data-language-local-name="Noors - Bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Neutrofil" title="Neutrofil – Pools" lang="pl" hreflang="pl" data-title="Neutrofil" data-language-autonym="Polski" data-language-local-name="Pools" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Granul%C3%B3cito_neutr%C3%B3filo" title="Granulócito neutrófilo – Portugees" lang="pt" hreflang="pt" data-title="Granulócito neutrófilo" data-language-autonym="Português" data-language-local-name="Portugees" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Granulocit_neutrofil" title="Granulocit neutrofil – Roemeens" lang="ro" hreflang="ro" data-title="Granulocit neutrofil" data-language-autonym="Română" data-language-local-name="Roemeens" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru badge-Q17437796 badge-featuredarticle mw-list-item" title="uitgelicht artikel"><a href="https://ru.wikipedia.org/wiki/%D0%9D%D0%B5%D0%B9%D1%82%D1%80%D0%BE%D1%84%D0%B8%D0%BB%D1%8B" title="Нейтрофилы – Russisch" lang="ru" hreflang="ru" data-title="Нейтрофилы" data-language-autonym="Русский" data-language-local-name="Russisch" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Neutrofil" title="Neutrofil – Servo-Kroatisch" lang="sh" hreflang="sh" data-title="Neutrofil" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="Servo-Kroatisch" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Neutrophil" title="Neutrophil – Simple English" lang="en-simple" hreflang="en-simple" data-title="Neutrophil" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Nevtrofilec" title="Nevtrofilec – Sloveens" lang="sl" hreflang="sl" data-title="Nevtrofilec" data-language-autonym="Slovenščina" data-language-local-name="Sloveens" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Granulocite_neutrofile" title="Granulocite neutrofile – Albanees" lang="sq" hreflang="sq" data-title="Granulocite neutrofile" data-language-autonym="Shqip" data-language-local-name="Albanees" class="interlanguage-link-target"><span>Shqip</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Neutrofil" title="Neutrofil – Servisch" lang="sr" hreflang="sr" data-title="Neutrofil" data-language-autonym="Српски / srpski" data-language-local-name="Servisch" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Neutrofil_granulocyt" title="Neutrofil granulocyt – Zweeds" lang="sv" hreflang="sv" data-title="Neutrofil granulocyt" data-language-autonym="Svenska" data-language-local-name="Zweeds" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%A8%E0%AE%9F%E0%AF%81%E0%AE%B5%E0%AE%AE%E0%AF%88%E0%AE%A8%E0%AE%BE%E0%AE%9F%E0%AE%BF" title="நடுவமைநாடி – Tamil" lang="ta" hreflang="ta" data-title="நடுவமைநாடி" data-language-autonym="தமிழ்" data-language-local-name="Tamil" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%99%E0%B8%B4%E0%B8%A7%E0%B9%82%E0%B8%97%E0%B8%A3%E0%B8%9F%E0%B8%B4%E0%B8%A5" title="นิวโทรฟิล – Thai" lang="th" hreflang="th" data-title="นิวโทรฟิล" data-language-autonym="ไทย" data-language-local-name="Thai" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/N%C3%B6trofil_polimorflar" title="Nötrofil 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lang="nl" dir="ltr"><figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/Bestand:Neutrophil_with_anthrax_copy.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Neutrophil_with_anthrax_copy.jpg/260px-Neutrophil_with_anthrax_copy.jpg" decoding="async" width="260" height="271" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Neutrophil_with_anthrax_copy.jpg/390px-Neutrophil_with_anthrax_copy.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Neutrophil_with_anthrax_copy.jpg/520px-Neutrophil_with_anthrax_copy.jpg 2x" data-file-width="2304" data-file-height="2403" /></a><figcaption>Microscopische opname van een neutrofiele granulocyt (geel) die een <a href="/wiki/Bacillus_anthracis" title="Bacillus anthracis">miltvuurbacterie</a> (<i>Bacillus anthracis</i>, oranje) opslokt door middel van <a href="/wiki/Fagocytose" title="Fagocytose">fagocytose</a>.</figcaption></figure> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/Bestand:Human_neutrophil_ingesting_MRSA.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/01/Human_neutrophil_ingesting_MRSA.jpg/260px-Human_neutrophil_ingesting_MRSA.jpg" decoding="async" width="260" height="343" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/01/Human_neutrophil_ingesting_MRSA.jpg/390px-Human_neutrophil_ingesting_MRSA.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/01/Human_neutrophil_ingesting_MRSA.jpg/520px-Human_neutrophil_ingesting_MRSA.jpg 2x" data-file-width="1894" data-file-height="2501" /></a><figcaption>Neutrofiele granulocyt die <a href="/wiki/MRSA" class="mw-redirect" title="MRSA">MRSA</a>-bacteriën opneemt.</figcaption></figure> <p>Een <b>neutrofiele granulocyt</b> of kortweg <b>neutrofiel</b> is een <a href="/wiki/Granule" title="Granule">granulaire</a> <a href="/wiki/Witte_bloedcel" title="Witte bloedcel">witte bloedcel</a> die een essentieel onderdeel vormt van het <a href="/wiki/Immuunsysteem" title="Immuunsysteem">immuunsysteem</a>. Neutrofielen vormen de grootste groep <a href="/wiki/Leukocyten" class="mw-redirect" title="Leukocyten">leukocyten</a> en maken ongeveer 60% uit van het totale aantal witte bloedcellen dat in een gezond lichaam aanwezig is.<sup id="cite_ref-Witko_1-0" class="reference"><a href="#cite_note-Witko-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Neutrofiele <a href="/wiki/Granulocyt" title="Granulocyt">granulocyten</a> zijn kort levende cellen die de primaire immuunrespons vormen waarmee infecties snel gecontroleerd worden. Neutrofielen <a href="/wiki/Fagocytose" title="Fagocytose">fagocyteren</a> <a href="/wiki/Bacteri%C3%ABn" title="Bacteriën">bacteriën</a>, <a href="/wiki/Virus_(biologie)" title="Virus (biologie)">virussen</a> en <a href="/wiki/Schimmels" title="Schimmels">schimmels</a>: ze zorgen ervoor dat deze vernietigd worden. Een tekort aan neutrofielen (<a href="/wiki/Neutropenie" title="Neutropenie">neutropenie</a>) leidt tot een grotere gevoeligheid voor vooral bacteriële infecties. </p><p>Een neutrofiel is een volgroeide granulaire witte bloedcel met een kern van twee tot vijf kwabben die met elkaar verbonden zijn door dunne <a href="/wiki/Chromatine" title="Chromatine">chromatinedraden</a>. De granulairen van de neutrofiel verkleuren door opname van een mengsel van <a href="/wiki/Zuur_(scheikunde)" title="Zuur (scheikunde)">zure</a> en <a href="/wiki/Basische" class="mw-redirect" title="Basische">basische</a> <a href="/wiki/Kleurstoffen" class="mw-redirect" title="Kleurstoffen">kleurstoffen</a>; vandaar de naam neutrofiel (neutraal; noch zuur noch basisch). </p><p>De hoofdfunctie van de neutrofielen bestaat uit het opnemen en verteren van specifieke stoffen en vooral van schadelijke <a href="/wiki/Bacteri%C3%ABn" title="Bacteriën">bacteriën</a>.<sup id="cite_ref-Klebanoff_2-0" class="reference"><a href="#cite_note-Klebanoff-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Dit proces van opname en inwendige vertering wordt <a href="/wiki/Fagocytose" title="Fagocytose">fagocytose</a> genoemd. Neutrofielen maken zich groter tot een soort capsule waarin de ziekteverwekker wordt gevangen. De ruimte waarin indringers vastzitten heet het <a href="/wiki/Fagosoom" class="mw-redirect" title="Fagosoom">fagosoom</a>. De granulairen in de neutrofielen bevatten afbraakenzymen die in <a href="/wiki/Fagosoom" class="mw-redirect" title="Fagosoom">fagosoom</a> vrijkomen om de indringers te verteren. Heel wat neutrofiele granulocyten overleven de strijd niet; veel dode granulocyten kunnen het lichaam verlaten als pus of etter. </p><p>De kern van een oudere neutrofiel is verdeeld in segmenten. In een vroeger stadium van de ontwikkeling van deze cel is de kern nog staafvormig. Een relatief grote hoeveelheid <a href="/wiki/Staafkernige_neutrofiele_granulocyt" title="Staafkernige neutrofiele granulocyt">staafkernigen</a> (dus veel jonge cellen) wordt geduid als een "linksverschuiving" en is een teken van acute infectie.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Bij een absoluut verhoogd aantal (staafkernige) neutrofiele granulocyten kan worden gedacht aan afwijkingen in het <a href="/wiki/Beenmerg" title="Beenmerg">beenmerg</a> waarbij er te veel leukocyten worden aangemaakt. </p> <div class="mw-heading mw-heading2"><h2 id="Overzicht_hematopoëtische_stamcel_rode_beenmerg"><span id="Overzicht_hematopo.C3.ABtische_stamcel_rode_beenmerg"></span>Overzicht hematopoëtische stamcel rode beenmerg</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Neutrofiele_granulocyt&veaction=edit&section=1" title="Bewerk dit kopje: Overzicht hematopoëtische stamcel rode beenmerg" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Neutrofiele_granulocyt&action=edit&section=1" title="De broncode bewerken van de sectie: Overzicht hematopoëtische stamcel rode beenmerg"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Onderstaand overzicht schetst de verschillende ontwikkelingsstadia van witte bloedcellen. Neutrofielen ontwikkelen zich uit <a href="/wiki/Myeloblast" title="Myeloblast">myeloblasten</a> in het rode beenmerg. De <a href="/wiki/Promyelocyt" title="Promyelocyt">promyelocyten</a> zijn precursors van de uiteindelijke granulocyten. </p> <table class="wikitable vatop" style="text-align:center"> <tbody><tr> <th colspan="10"><a href="/wiki/Hematopo%C3%ABse" title="Hematopoëse">Hematopoëse</a> </th></tr> <tr> <td colspan="8"><a href="/wiki/Leukopo%C3%ABse" title="Leukopoëse">Leukopoëse</a> </td> <td><a href="/wiki/Erytropo%C3%ABse" title="Erytropoëse">Erytropoëse</a> </td> <td><a href="/wiki/Trombopo%C3%ABse" title="Trombopoëse">Trombopoëse</a> </td></tr> <tr> <td rowspan="3" colspan="3"><br /><a href="/wiki/Myeloblast" title="Myeloblast">Myeloblast</a> </td> <td rowspan="3"><br /><a href="/wiki/Monoblast" title="Monoblast">Monoblast</a> </td> <td rowspan="3" colspan="3"><br /><a href="/wiki/Lymfoblast" title="Lymfoblast">Lymfoblast</a> </td> <td rowspan="4"> </td> <td><a href="/wiki/Pro-erytroblast" title="Pro-erytroblast">Pro-erytroblast</a> </td> <td rowspan="3"><br /><a href="/wiki/Megakaryoblast" title="Megakaryoblast">Megakaryoblast</a> </td></tr> <tr> <td><a href="/wiki/Erytroblast" title="Erytroblast">Erytroblast</a> </td></tr> <tr> <td><a href="/wiki/Normoblast" title="Normoblast">Normoblast</a> </td></tr> <tr> <td colspan="3"><a href="/wiki/Promyelocyt" title="Promyelocyt">Promyelocyt</a> </td> <td><a href="/wiki/Monocyt" title="Monocyt">Monocyt</a> </td> <td colspan="3"><a href="/wiki/Lymfocyt" title="Lymfocyt">Lymfocyt</a> </td> <td><a href="/wiki/Reticulocyt" title="Reticulocyt">Reticulocyt</a> </td> <td><a href="/wiki/Megakaryocyt" title="Megakaryocyt">Megakaryocyt</a> </td></tr> <tr> <td><a class="mw-selflink selflink">Neutrofiele<br />granulocyt</a> </td> <td><a href="/wiki/Basofiele_granulocyt" title="Basofiele granulocyt">Basofiele<br />granulocyt</a> </td> <td><a href="/wiki/Eosinofiele_granulocyt" title="Eosinofiele granulocyt">Eosinofiele<br />granulocyt</a> </td> <td><a href="/wiki/Macrofaag" title="Macrofaag">Macrofaag</a> </td> <td><a href="/wiki/B-cel" title="B-cel">B-cel</a> </td> <td><a href="/wiki/T-cel" title="T-cel">T-cel</a> </td> <td><a href="/wiki/NK-cel" title="NK-cel">NK-cel</a> </td> <td><a href="/wiki/Mestcel" title="Mestcel">Mastocyt</a> </td> <td><a href="/wiki/Rode_bloedcel" title="Rode bloedcel">Erytrocyt</a> </td> <td><a href="/wiki/Bloedplaatje" title="Bloedplaatje">Trombocyt</a> </td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="Zie_ook">Zie ook</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Neutrofiele_granulocyt&veaction=edit&section=2" title="Bewerk dit kopje: Zie ook" class="mw-editsection-visualeditor"><span>bewerken</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Neutrofiele_granulocyt&action=edit&section=2" title="De broncode bewerken van de sectie: Zie ook"><span>brontekst bewerken</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Basofiele_granulocyt" title="Basofiele granulocyt">Basofiele granulocyt</a></li> <li><a href="/wiki/Eosinofiele_granulocyt" title="Eosinofiele granulocyt">Eosinofiele granulocyt</a></li></ul> <div class="toccolours appendix" role="presentation" style="font-size:90%; margin:1em 0 -0.5em; clear:both;"> <div><span style="font-weight:bold">Bronnen, noten en/of referenties</span></div> <div class="reflist" style="list-style-type: decimal;"><div class="mw-references-wrap"><ol class="references"> <li id="cite_note-Witko-1"><span class="mw-cite-backlink"><a href="#cite_ref-Witko_1-0">↑</a></span> <span class="reference-text"><span class="citation" id="CITEREF2000"><style data-mw-deduplicate="TemplateStyles:r67679320">.mw-parser-output .taalaanduiding{font-family:sans-serif;font-size:85%;cursor:help;color:var(--color-subtle,#555)}.mw-parser-output .taalaanduiding span{border-bottom:1px dotted var(--color-subtle,#555)}</style><span class="taalaanduiding" title="Taal: Engels">(<span>en</span>) </span><span style="font-variant:small-caps;">Witko-Sarsat V, Rieu P, Descamps-Latscha B, Lesavre P, Halbwachs-Mecarelli L</span> (2000). <cite>Neutrophils: molecules, functions and pathophysiological aspects</cite>. <i>Laboratory Investigation; A Journal of Technical Methods and Pathology</i> <b>80</b> (5): 617–53. <a href="/wiki/PubMed" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/10830774">10830774</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>: <a rel="nofollow" class="external text" href="https://doi.org/10.1038/labinvest.3780067">10.1038/labinvest.3780067</a>. </span></span> </li> <li id="cite_note-Klebanoff-2"><span class="mw-cite-backlink"><a href="#cite_ref-Klebanoff_2-0">↑</a></span> <span class="reference-text"><span class="citation" id="CITEREF1978"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r67679320"><span class="taalaanduiding" title="Taal: Engels">(<span>en</span>) </span><span style="font-variant:small-caps;">Klebanoff SJ, Clark RA</span> (1978). <cite><i>The Neutrophil: Function and Clinical Disorders</i></cite>. Elsevier/North-Holland Amsterdam. <span class="ISBN"><a href="/wiki/Speciaal:Boekbronnen/978-0-444-80020-6" title="Speciaal:Boekbronnen/978-0-444-80020-6">ISBN 978-0-444-80020-6</a></span>.</span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><a href="#cite_ref-3">↑</a></span> <span class="reference-text"><span class="citation" id="CITEREF2002_465"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r67679320"><span class="taalaanduiding" title="Taal: Engels">(<span>en</span>) </span><span style="font-variant:small-caps;">Cohen S, Burns RC</span> (2002). <cite><i>Pathways of the Pulp</i></cite>, 8th. Mosby, St. Louis, p. 465.</span></span> </li> </ol></div></div> </div> <div class="interProject commons mw-list-item" style="display:none;"><a href="https://commons.wikimedia.org/wiki/Category:Neutrophils#mw-subcategories" class="extiw" title="commons:Category:Neutrophils">Mediabestanden</a></div> <div class="interProjectTemplate interProject-groot toccolours" style="display:flex; gap:1em; align-items:center; clear:both; margin:1em 0 -0.5em 0;"> <div style="min-width:max-content;"><span class="noviewer noresize" typeof="mw:File"><a href="/wiki/Bestand:Commons-logo.svg" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/25px-Commons-logo.svg.png" decoding="async" width="25" height="34" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/38px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/50px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span></div> <div>Zie de categorie <i><b><a href="https://commons.wikimedia.org/wiki/Category:Neutrophils#mw-subcategories" class="extiw" title="commons:Category:Neutrophils">Neutrophils</a></b></i> van <a href="/wiki/Wikimedia_Commons" title="Wikimedia Commons">Wikimedia Commons</a> voor mediabestanden over dit onderwerp.</div> </div> <style data-mw-deduplicate="TemplateStyles:r67837862">.mw-parser-output .navigatie{position:relative;clear:both;overflow:auto;margin:1em auto -0.5em;padding:2px;background-color:var(--background-color-neutral-subtle,#f8f9fa);border:1px solid var(--border-color-base,#a2a9b1);text-align:center;font-size:87%}.mw-parser-output .navigatie-bewerken{margin-left:0.5em}.mw-parser-output .navigatie-bewerken .mw-ui-icon::before{background-size:0.9em}.mw-parser-output .navigatie-afb-links,.mw-parser-output .navigatie-afb-rechts{position:absolute}.mw-parser-output .navigatie-afb-rechts{right:2px}.mw-parser-output .navigatie-afb-groot{float:right;padding-left:0.5em}.mw-parser-output .navigatie-titel{background-color:#ddeef8;padding:2px 5.5em;font-weight:bold}.mw-parser-output .navigatie-inhoud{padding:0.5em}.mw-parser-output .navigatie-inhoud p:first-child{margin:0}.mw-parser-output .navigatie div[style*="background-color"],.mw-parser-output .navigatie div[style*="background"]{color:inherit}@media screen{html.skin-theme-clientpref-night .mw-parser-output .navigatie-titel{background-color:var(--background-color-interactive,#eaecf0)!important}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navigatie-titel{background-color:var(--background-color-interactive,#eaecf0)!important}}</style> <div class="navigatie" role="navigation" aria-labelledby="Immunologie"> <div class="navigatie-afb-links noviewer"><div class="navigatie-bewerken show-autoconfirmed nomobile"><span class="nowrap skin-invert-image"><span typeof="mw:File"><a href="/wiki/Sjabloon:Navigatie_immunologie" title="Sjabloon:Navigatie immunologie"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c4/OOjs_UI_icon_article-ltr.svg/16px-OOjs_UI_icon_article-ltr.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c4/OOjs_UI_icon_article-ltr.svg/24px-OOjs_UI_icon_article-ltr.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c4/OOjs_UI_icon_article-ltr.svg/32px-OOjs_UI_icon_article-ltr.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span> · <span typeof="mw:File"><a href="https://en.wikipedia.org/wiki/nl:Overleg_sjabloon:Navigatie_immunologie" title="Overleg sjabloon"><img alt="Overleg sjabloon" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/40/OOjs_UI_icon_speechBubbles-ltr.svg/16px-OOjs_UI_icon_speechBubbles-ltr.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/40/OOjs_UI_icon_speechBubbles-ltr.svg/24px-OOjs_UI_icon_speechBubbles-ltr.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/40/OOjs_UI_icon_speechBubbles-ltr.svg/32px-OOjs_UI_icon_speechBubbles-ltr.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span> · <span typeof="mw:File"><a href="//nl.wikipedia.org/w/index.php?title=Sjabloon:Navigatie_immunologie&action=edit" title="Sjabloon bewerken"><img alt="Sjabloon bewerken" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr.svg/16px-OOjs_UI_icon_edit-ltr.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr.svg/24px-OOjs_UI_icon_edit-ltr.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr.svg/32px-OOjs_UI_icon_edit-ltr.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></div></div> <div id="Immunologie" class="navigatie-titel"><a href="/wiki/Immunologie" title="Immunologie">Immunologie</a></div> <div class="navigatie-inhoud"> <style data-mw-deduplicate="TemplateStyles:r67785531">.mw-parser-output .navigatie-tabel{margin:0 auto 0 auto;text-align:left}.mw-parser-output .navigatie-tabel .links{text-align:right}.mw-parser-output .navigatie-tabel .rechts{padding-left:0.5em}@media screen and (max-width:640px){.mw-parser-output .navigatie-tabel tr{display:grid;grid-template-columns:1fr;width:100%;margin-bottom:0.5em}.mw-parser-output .navigatie-tabel tr:last-of-type{margin-bottom:0}.mw-parser-output .navigatie-tabel .links{text-align:unset}.mw-parser-output .navigatie-tabel .rechts{padding:unset}}</style><table class="navigatie-tabel vatop" cellpadding="0" cellspacing="0" style=""><tbody><tr><td class="links" style=""><b>Principe:</b></td><td class="rechts"><a href="/wiki/Antigeen" title="Antigeen">antigeen</a> · <a href="/wiki/Cytokine" title="Cytokine">cytokine</a> · <a href="/wiki/Cytotoxine" title="Cytotoxine">cytotoxine</a> · <a href="/wiki/Epitoop" title="Epitoop">epitoop</a> · <a href="/wiki/Factor_I" title="Factor I">factor I</a> · <a href="/wiki/Humaan_leukocytenantigeen" title="Humaan leukocytenantigeen">HLA</a> · <a href="/wiki/Lymfeklier" title="Lymfeklier">lymfeklier</a> · <a href="/wiki/Peyerse_plaat" title="Peyerse plaat">Peyerse plaat</a></td></tr><tr><td class="links"><b>Celtypen:</b></td><td class="rechts"><a href="/wiki/B-cel" title="B-cel">B-cel</a> · <a href="/wiki/B-geheugencel" title="B-geheugencel">B-geheugencel</a> · <a href="/wiki/T-cel" title="T-cel">T-cel</a> · <a href="/wiki/T-geheugencel" title="T-geheugencel">T-geheugencel</a> · <a href="/wiki/T-remmercel" class="mw-redirect" title="T-remmercel">T-remmercel</a> · <a href="/wiki/T-helpercel" title="T-helpercel">T-helpercel</a> · <a href="/wiki/Cytotoxische_T-cel" title="Cytotoxische T-cel">cytotoxische T-cel</a> · <a href="/wiki/Fagocyt" title="Fagocyt">fagocyt</a> · <a href="/wiki/Macrofaag" title="Macrofaag">macrofaag</a> · <a href="/wiki/NK-cel" title="NK-cel">NK-cel</a> · <a href="/wiki/Basofiele_granulocyt" title="Basofiele granulocyt">basofiele granulocyt</a> · <a class="mw-selflink selflink">neutrofiele granulocyt</a> · <a href="/wiki/Eosinofiele_granulocyt" title="Eosinofiele granulocyt">eosinofiele granulocyt</a> · <a href="/wiki/Dendritische_cel" title="Dendritische cel">dendritische cel</a> · <a href="/wiki/Mestcel" title="Mestcel">mestcel</a></td></tr><tr><td class="links"><b>Aangeboren:</b></td><td class="rechts"><a href="/wiki/Complementsysteem" title="Complementsysteem">complementsysteem</a> · <a href="/wiki/Toll-like_receptor" title="Toll-like receptor">toll-like receptor</a></td></tr><tr><td class="links"><b>Humorale afweer:</b></td><td class="rechts"><a href="/wiki/Immunoglobuline" title="Immunoglobuline">antilichaam</a> / <a href="/wiki/Immunoglobuline" title="Immunoglobuline">antistof</a> (<a href="/wiki/Immunoglobuline_G" title="Immunoglobuline G">IgG</a> · <a href="/wiki/Immunoglobuline_A" title="Immunoglobuline A">IgA</a> · <a href="/wiki/Immunoglobuline_M" title="Immunoglobuline M">IgM</a> · <a href="/wiki/IgD" class="mw-redirect" title="IgD">IgD</a> · <a href="/wiki/IgE" class="mw-redirect" title="IgE">IgE</a>) · <a href="/wiki/Class_switching" title="Class switching">class switching</a></td></tr><tr><td class="links"><b>Technieken:</b></td><td class="rechts"><a href="/wiki/ELISA" title="ELISA">ELISA</a> · <a href="/wiki/Immunofenotypering" title="Immunofenotypering">immunofenotypering</a> · <a href="/wiki/Immunofixatie" title="Immunofixatie">immunofixatie</a> · <a href="/wiki/Immuunhistochemie" title="Immuunhistochemie">immuunhistochemie</a> · <a href="/wiki/Inenting" title="Inenting">vaccinatie</a></td></tr></tbody></table> </div></div> <!-- NewPP limit report Parsed by mw‐web.eqiad.main‐7649cfcddd‐xg8zf Cached time: 20241127114647 Cache expiry: 2592000 Reduced 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