Science Technology Stories & Careers

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class="hero__inner"> <figure class="hero__bg"> </figure> <div class="hero__content"> <div class="hero__content-container"> <div class="hero__content-category"> <span>Science</span> </div> <div class="hero__content-title"> <h1>Accelerating Research Through Technology</h1> </div> <div class="hero__content-copy"> <p>Our science technology team accelerates the pace of biomedical research by building models, methods, tools, applications, and datasets for scientists. Our technology-driven approach helps researchers come to meaningful conclusions about human biology — spurring new discoveries about the molecular underpinnings of health and disease.</p> </div> </div> </div> </div> </section> <section class="featured-tech"> <figure class="featured-tech__bg"> <video autoplay muted loop> <source src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2021/12/scitech.m4v" type="video/mp4"> </video> </figure> <div class="featured-tech__container"> <a class="featured-tech__item color-purple" href="#virtual-cells"> <figure class="featured-tech__icon"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2024/03/virtual-cells-icon.png" alt=""> </figure> <span class="featured-tech__title"> Virtual Cells </span> <p class="featured-tech__content"> Leveraging AI to build virtual cells that are capable of predicting the behavior of healthy and diseased cells </p> <figure class="featured-tech__arrow mobile-only"> <svg xmlns="http://www.w3.org/2000/svg" width="32" height="15" viewBox="0 0 32 15" fill="none"> <path d="M31.2034 8.26997C31.594 7.87945 31.594 7.24628 31.2034 6.85576L24.8395 0.491798C24.449 0.101273 23.8158 0.101273 23.4253 0.491798C23.0347 0.882322 23.0347 1.51549 23.4253 1.90601L29.0821 7.56287L23.4253 13.2197C23.0347 13.6102 23.0347 14.2434 23.4253 14.6339C23.8158 15.0245 24.449 15.0245 24.8395 14.6339L31.2034 8.26997ZM0.496338 8.56287L30.4963 8.56287L30.4963 6.56287L0.496338 6.56287L0.496338 8.56287Z" fill="#21FFFD"/> </svg> </figure> </a> <a class="featured-tech__item color-default" href="#infectious-disease"> <figure class="featured-tech__icon"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2024/03/infectious-disease-icon.png" alt=""> </figure> <span class="featured-tech__title"> Infectious Disease </span> <p class="featured-tech__content"> Enabling access to high-resolution, actionable insights to accelerate the detection, identification and tracking of infectious disease </p> <figure class="featured-tech__arrow mobile-only"> <svg xmlns="http://www.w3.org/2000/svg" width="32" height="15" viewBox="0 0 32 15" fill="none"> <path d="M31.2034 8.26997C31.594 7.87945 31.594 7.24628 31.2034 6.85576L24.8395 0.491798C24.449 0.101273 23.8158 0.101273 23.4253 0.491798C23.0347 0.882322 23.0347 1.51549 23.4253 1.90601L29.0821 7.56287L23.4253 13.2197C23.0347 13.6102 23.0347 14.2434 23.4253 14.6339C23.8158 15.0245 24.449 15.0245 24.8395 14.6339L31.2034 8.26997ZM0.496338 8.56287L30.4963 8.56287L30.4963 6.56287L0.496338 6.56287L0.496338 8.56287Z" fill="#21FFFD"/> </svg> </figure> </a> <a class="featured-tech__item color-green" href="#single-cell-biology"> <figure class="featured-tech__icon"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2024/03/single-cell-biology-icon.png" alt=""> </figure> <span class="featured-tech__title"> Cell Science </span> <p class="featured-tech__content"> Accelerating the development and application of tools and technologies to better and more quickly understand how disease manifests in cells and tissues </p> <figure class="featured-tech__arrow mobile-only"> <svg xmlns="http://www.w3.org/2000/svg" width="32" height="15" viewBox="0 0 32 15" fill="none"> <path d="M31.2034 8.26997C31.594 7.87945 31.594 7.24628 31.2034 6.85576L24.8395 0.491798C24.449 0.101273 23.8158 0.101273 23.4253 0.491798C23.0347 0.882322 23.0347 1.51549 23.4253 1.90601L29.0821 7.56287L23.4253 13.2197C23.0347 13.6102 23.0347 14.2434 23.4253 14.6339C23.8158 15.0245 24.449 15.0245 24.8395 14.6339L31.2034 8.26997ZM0.496338 8.56287L30.4963 8.56287L30.4963 6.56287L0.496338 6.56287L0.496338 8.56287Z" fill="#21FFFD"/> </svg> </figure> </a> <a class="featured-tech__item color-yellow" href="#imaging"> <figure class="featured-tech__icon"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2021/11/icon-imaging.png" alt=""> </figure> <span class="featured-tech__title"> Imaging </span> <p class="featured-tech__content"> Collaborating with the open source napari project to make reproducible quantitative image analysis more accessible, helping scientists make more discoveries, faster </p> <figure class="featured-tech__arrow mobile-only"> <svg xmlns="http://www.w3.org/2000/svg" width="32" height="15" viewBox="0 0 32 15" fill="none"> <path d="M31.2034 8.26997C31.594 7.87945 31.594 7.24628 31.2034 6.85576L24.8395 0.491798C24.449 0.101273 23.8158 0.101273 23.4253 0.491798C23.0347 0.882322 23.0347 1.51549 23.4253 1.90601L29.0821 7.56287L23.4253 13.2197C23.0347 13.6102 23.0347 14.2434 23.4253 14.6339C23.8158 15.0245 24.449 15.0245 24.8395 14.6339L31.2034 8.26997ZM0.496338 8.56287L30.4963 8.56287L30.4963 6.56287L0.496338 6.56287L0.496338 8.56287Z" fill="#21FFFD"/> </svg> </figure> </a> </div> </section> <section class="tech-glossary"> <div class="tech-glossary__container"> <aside class="tech-glossary__nav"> <ul> <li class="color-purple " data-category="virtual-cells">Virtual Cells</li> <li class="color-default " data-category="infectious-disease">Infectious Disease</li> <li class="color-green " data-category="cell-science">Cell Science</li> <li class="color-yellow " data-category="imaging">Imaging</li> <li class="color-pink desktop-only" data-category="technology-we-support">Technology We Support</li> </ul> </aside> <div class="tech-glossary__items-wrapper"> <div class="tech-glossary__items-category color-purple" id="virtual-cells"> <span class="tech-glossary__items-title"> Virtual Cells </span> <div class="tech-glossary__items-single"> <a href="https://chanzuckerberg.com/science/technology/virtual-cells/" class="fill-link" target="_blank" title="Virtual Cells"></a> <figure class="tech-glossary__items-single-img"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2024/03/virtual-images-of-proteins-expressions-over-pre-existing-reference-markers.jpg" alt="An irregular red and green shape with blue ovals throughout, taking up most of a black background."> </figure> <div class="tech-glossary__items-single-content-wrapper"> <a href="https://chanzuckerberg.com/science/technology/virtual-cells/" target="_blank" class="tech-glossary__items-single-title"> Virtual Cells </a> <p class="tech-glossary__items-single-copy"> We’re leveraging AI to build virtual cells that scientists can use to understand how cells work in healthy and diseased states, which will have broad applications for biomedical research, disease diagnosis and therapeutic development. We believe this effort will deepen the scientific community’s understanding of human health and disease at a molecular level. </p> </div> </div> </div> <div class="tech-glossary__items-category color-default" id="infectious-disease"> <span class="tech-glossary__items-title"> Infectious Disease </span> <div class="tech-glossary__items-single"> <a href="https://czid.org/" class="fill-link" target="_blank" title="Chan Zuckerberg ID"></a> <figure class="tech-glossary__items-single-img"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2021/12/1.jpg" alt=""> </figure> <div class="tech-glossary__items-single-content-wrapper"> <a href="https://czid.org/" target="_blank" class="tech-glossary__items-single-title"> Chan Zuckerberg ID </a> <p class="tech-glossary__items-single-copy"> Chan Zuckerberg ID (CZ ID) is an open source metagenomics analysis platform that helps researchers rapidly identify new and emerging infectious diseases. CZ ID processes sequencing data to provide actionable information on the state of pathogens in a given set of samples. This allows scientists to make data-driven decisions about when to deploy antibiotics, where to prioritize immunization campaigns, how to shape vector-borne disease surveillance and control efforts, and more. </p> </div> </div> </div> <div class="tech-glossary__items-category color-green" id="cell-science"> <span class="tech-glossary__items-title"> Cell Science </span> <div class="tech-glossary__items-single"> <a href="http://czcellxgene.org/" class="fill-link" target="_blank" title="Chan Zuckerberg CELL by GENE"></a> <figure class="tech-glossary__items-single-img"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2022/08/cellxgene-explorer.jpg" alt=""> </figure> <div class="tech-glossary__items-single-content-wrapper"> <a href="http://czcellxgene.org/" target="_blank" class="tech-glossary__items-single-title"> Chan Zuckerberg CELL by GENE </a> <p class="tech-glossary__items-single-copy"> Chan Zuckerberg CELL by GENE (CZ CELLxGENE) is an open source platform that allows scientists to access, analyze and annotate high-dimensional single-cell data at scale, so they can quickly surface new insights that could lead to discoveries in treating disease. Through standardization and integration of published single-cell datasets, the platform’s database enables scientists to answer questions about the function of cells in seconds, instead of executing experiments that take years. </p> </div> </div> </div> <div class="tech-glossary__items-category color-yellow" id="imaging"> <span class="tech-glossary__items-title"> Imaging </span> <div class="tech-glossary__items-single"> <a href="https://www.napari-hub.org/" class="fill-link" target="_blank" title="napari hub"></a> <figure class="tech-glossary__items-single-img"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2021/12/napari-hub.png" alt=""> </figure> <div class="tech-glossary__items-single-content-wrapper"> <a href="https://www.napari-hub.org/" target="_blank" class="tech-glossary__items-single-title"> napari hub </a> <p class="tech-glossary__items-single-copy"> Built by the CZI imaging technology team, the napari hub helps researchers find high-quality image analysis methods that solve their unique data analysis needs. The napari hub hosts a growing ecosystem of open source, community-built napari plugins to help researchers find trusted, relevant, high-quality analysis methods that they can use to quantify their data and gain insights into biology. </p> </div> </div> <div class="tech-glossary__items-outro"> <figure class="icon"> <svg width="21" height="21" viewBox="0 0 21 21" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M19.1731 10.4C19.1731 9.22623 18.9122 8.11763 18.4557 7.00904C17.9993 5.96566 17.3471 4.9875 16.6298 4.27018C15.9125 3.55285 14.9343 2.90073 13.8909 2.44425C12.8476 1.98777 11.6738 1.72694 10.5 1.72694C9.32615 1.72694 8.21756 1.98777 7.10897 2.44425C6.06559 2.90073 5.08741 3.55285 4.37008 4.27018C3.65276 4.9875 3.00065 5.96566 2.54417 7.00904C2.08769 8.05242 1.82684 9.22623 1.82684 10.4C1.82684 12.2912 2.41375 13.9867 3.52234 15.5517C4.63094 17.1168 6.1308 18.1602 7.8915 18.6819V16.3995C7.36981 16.4647 7.10896 16.4647 6.97854 16.4647C6.00037 16.4647 5.28304 16.0082 4.89178 15.0953C4.76135 14.7692 4.56572 14.4431 4.37008 14.2475C4.30487 14.1823 4.23966 14.1171 4.10924 13.9867C3.97882 13.8562 3.84839 13.791 3.71797 13.6606C3.58755 13.5302 3.52234 13.465 3.52234 13.465C3.52234 13.3346 3.65276 13.3346 3.9136 13.3346C4.17445 13.3346 4.4353 13.3998 4.63093 13.5302C4.82657 13.6606 5.0222 13.791 5.15263 13.9867C5.28305 14.1823 5.41347 14.3779 5.6091 14.5736C5.73953 14.7692 5.93516 14.8996 6.1308 15.0301C6.32643 15.1605 6.58727 15.2257 6.91333 15.2257C7.3046 15.2257 7.63065 15.1605 8.02192 15.0301C8.15235 14.5084 8.4784 14.1171 8.86967 13.791C7.36981 13.6606 6.26121 13.2693 5.54389 12.6824C4.82656 12.0955 4.4353 11.0521 4.4353 9.61749C4.4353 8.57411 4.76135 7.66117 5.41347 6.94385C5.28305 6.55258 5.21783 6.1613 5.21783 5.77003C5.21783 5.24834 5.34826 4.72666 5.6091 4.27018C6.1308 4.27018 6.58727 4.33538 6.97854 4.53102C7.3698 4.72665 7.82629 4.98749 8.34798 5.37876C9.0653 5.24833 9.78263 5.11792 10.6304 5.11792C11.3477 5.11792 12.065 5.18314 12.7171 5.31356C13.2388 4.92229 13.6953 4.66144 14.0866 4.53102C14.4778 4.33538 14.9343 4.27018 15.456 4.27018C15.7169 4.72666 15.8473 5.24834 15.8473 5.77003C15.8473 6.1613 15.7821 6.55257 15.6517 6.87863C16.3038 7.59595 16.6298 8.50892 16.6298 9.5523C16.6298 10.9869 16.2386 11.9651 15.5212 12.6172C14.8039 13.2693 13.6953 13.5954 12.1954 13.7258C12.8476 14.1823 13.1084 14.7692 13.1084 15.4865V18.5515C14.9343 17.9646 16.369 16.9212 17.4776 15.4213C18.5862 13.9867 19.1731 12.2912 19.1731 10.4ZM20.8686 10.4C20.8686 12.2912 20.4121 14.0519 19.4991 15.6169C18.5862 17.2472 17.2819 18.4862 15.7169 19.3992C14.0866 20.3122 12.3911 20.7686 10.5 20.7686C8.60883 20.7686 6.84812 20.3122 5.28305 19.3992C3.65276 18.4862 2.41375 17.182 1.50079 15.6169C0.587827 13.9867 0.131344 12.2912 0.131344 10.4C0.131344 8.50891 0.587827 6.7482 1.50079 5.18313C2.41375 3.55285 3.71797 2.31384 5.28305 1.40088C6.91333 0.487921 8.60883 0.0314371 10.5 0.0314371C12.3911 0.0314371 14.1518 0.487921 15.7169 1.40088C17.3471 2.31384 18.5862 3.61806 19.4991 5.18313C20.4121 6.7482 20.8686 8.50891 20.8686 10.4Z" fill="white"/> </svg> </figure> <p>Visit our <a href="https://github.com/chanzuckerberg/">GitHub organization</a> to browse projects.</p> </div> </div> <div class="tech-glossary__items-category color-pink" id="technology-we-support"> <span class="tech-glossary__items-title"> Technology We Support </span> <p class="tech-glossary__items-intro"> Beyond building and disseminating technology in collaboration with the science community, CZI Science also works with many community-led projects that we partner with or support through grants to help advance our mission. </p> <div class="tech-glossary__items-single"> <a href="https://chanzuckerberg.com/eoss/" class="fill-link" target="_blank" title="Essential Open Source Software for Science"></a> <figure class="tech-glossary__items-single-img"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2021/12/6.jpg" alt=""> </figure> <div class="tech-glossary__items-single-content-wrapper"> <a href="https://chanzuckerberg.com/eoss/" target="_blank" class="tech-glossary__items-single-title"> Essential Open Source Software for Science </a> <p class="tech-glossary__items-single-copy"> CZI’s Essential Open Source Software for Science program supports software maintenance, growth, development, and community engagement for over a hundred critical open source tools used by scientists globally. </p> </div> </div> <div class="tech-glossary__items-single"> <a href="https://chanzuckerberg.com/science/programs-resources/rare-as-one/network/" class="fill-link" target="_blank" title="TOOLS TO SCALE PATIENT DRIVEN-RESEARCH "></a> <figure class="tech-glossary__items-single-img"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2021/11/Group-1963.png" alt=""> </figure> <div class="tech-glossary__items-single-content-wrapper"> <a href="https://chanzuckerberg.com/science/programs-resources/rare-as-one/network/" target="_blank" class="tech-glossary__items-single-title"> TOOLS TO SCALE PATIENT DRIVEN-RESEARCH </a> <p class="tech-glossary__items-single-copy"> We enable and scale patient-driven research by supporting and amplifying the work of rare disease patient organizations by providing them with tools to leverage patient data, scientific knowledge, and researcher and physician connections in order to accelerate research toward new treatments and cures. </p> </div> </div> <div class="tech-glossary__items-single"> <a href="https://chanzuckerberg.com/science/programs-resources/open-science/grants/preprints/" class="fill-link" target="_blank" title="BIORXIV & MEDRXIV"></a> <figure class="tech-glossary__items-single-img"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2021/12/8.jpg" alt=""> </figure> <div class="tech-glossary__items-single-content-wrapper"> <a href="https://chanzuckerberg.com/science/programs-resources/open-science/grants/preprints/" target="_blank" class="tech-glossary__items-single-title"> BIORXIV & MEDRXIV </a> <p class="tech-glossary__items-single-copy"> Scientists post preprints, or scientific papers published prior to peer review, on servers such as bioRxiv and medRxiv, which dramatically accelerates their ability to access information and build on each others’ work. </p> </div> </div> <div class="tech-glossary__items-single"> <a href="https://protocols.io/" class="fill-link" target="_blank" title="protocols.io"></a> <figure class="tech-glossary__items-single-img"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2021/12/9.jpg" alt=""> </figure> <div class="tech-glossary__items-single-content-wrapper"> <a href="https://protocols.io/" target="_blank" class="tech-glossary__items-single-title"> protocols.io </a> <p class="tech-glossary__items-single-copy"> Protocols.io is a platform that allows researchers to discover and openly share up-to-date scientific methods. </p> </div> </div> </div> </div> </div> </section> <section class="module module__careers bg-gray overlay-default"> <div class="module__careers-container"> <figure class="module__careers-img"> <img src="https://tech.chanzuckerberg.com/wp-content/uploads/sites/7/2024/07/NehaC_Portrait_quote.png" alt=""> </figure> <div class="module__careers-content-wrapper"> <div class="module__careers-content"> <h3>Work With Us</h3> <p>At CZI, we believe that collaboration harnesses the collective expertise, creativity, and diverse perspectives of individuals, amplifying their impact and driving innovation to new heights. We work hand-in-hand with researchers to build the technology and software that accelerate scientific discoveries. 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