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(PDF) Bacterial etiology and serotypes of acute otitis media in Mexican children | Yolanda Cervantes - Academia.edu

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true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":52291331,"created_at":"2021-09-14T04:37:56.466-07:00","from_world_paper_id":172953386,"updated_at":"2024-11-23T17:12:39.172-08:00","_data":{"publisher":"Elsevier","grobid_abstract":"Streptococcus pneumoniae and Haemophilus influenzae have been consistently reported to be the two major bacterial pathogens responsible for acute otitis media (AOM), mainly from studies in the US and Europe. However, data on bacterial pathogens causing AOM in Latin America are limited. Understanding the relative importance of these pathogens in a specific setting, the serotype distribution, and their antibiotic susceptibility levels is important to provide local vaccine and treatment recommendations. We therefore conducted a prospective, multi-center, tympanocentesis-based epidemiological study of Mexican children three months to less than five years of age. Fifty percent of episodes were in children who had received at least one dose of PCV7. Overall, 64% of samples were culture positive for bacterial pathogens. H. influenzae and S. pneumoniae were the leading causes of bacterial AOM, detected in 34% and 29% of AOM episodes, respectively. The most commonly isolated S. pneumoniae serotypes were 19A, 19F and 23F. All H. influenzae isolates were identified as non-typeable. Seventy-four percent of S. pneumoniae were susceptible to penicillin, while 97% were susceptible to amoxicillin/clavulanate. All H. influenzae samples were susceptible to amoxicillin/clavulanate and cefotaxime, 95% to cefuroxime and 75% to ampicillin. Both S. pneumoniae and non-typable H. influenzae represent important targets for vaccination strategies to reduce AOM in Mexican children.","publication_date":"2011,,","publication_name":"Vaccine","grobid_abstract_attachment_id":"69624393"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Bacterial etiology and serotypes of acute otitis media in Mexican children","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [187588219]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div 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translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Bacterial etiology and serotypes of acute otitis media in Mexican children</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="187588219" href="https://independent.academia.edu/YolandaCervantes15"><img alt="Profile image of Yolanda Cervantes" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Yolanda Cervantes</a></div><p class="ds-work-card--detail ds2-5-body-sm">2011, Vaccine</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" 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data-landing_url="https://www.academia.edu/52291331/Bacterial_etiology_and_serotypes_of_acute_otitis_media_in_Mexican_children" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="108008291" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/108008291/Non_typeable_Haemophilus_influenzae_and_Streptococcus_pneumoniaeas_primary_causes_of_acute_otitis_media_in_colombian_children_a_prospective_study">Non-typeable Haemophilus influenzae and Streptococcus pneumoniaeas primary causes of acute otitis media in colombian children: a 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This study estimated the baseline etiology, distribution, and antibiotic susceptibility of bacterial serotypes that causes AOM in children aged &amp;lt;5 years in a public setting in Santiago, Chile.Children aged ≥3 months and &amp;lt;5 years referred to the physician for treatment of AOM episodes (with an onset of symptoms &amp;lt;72 h) were enrolled between September 2009 and September 2010. Middle ear fluid (MEF) was collected by tympanocentesis or by otorrhea for identification and serotyping of bacteria. Antibacterial susceptibility was tested using E-test (etrack: 112671).Of 160 children (mean age 27.10 ± 15.83 months) with AOM episodes, 164 MEF samples (1 episode each from 156 children; 2 episodes each from 4 children) were collected. 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