CINXE.COM
Health | NIST
<!DOCTYPE html> <html lang="en" dir="ltr" prefix="content: http://purl.org/rss/1.0/modules/content/ dc: http://purl.org/dc/terms/ foaf: http://xmlns.com/foaf/0.1/ og: http://ogp.me/ns# rdfs: http://www.w3.org/2000/01/rdf-schema# schema: http://schema.org/ sioc: http://rdfs.org/sioc/ns# sioct: http://rdfs.org/sioc/types# skos: http://www.w3.org/2004/02/skos/core# xsd: http://www.w3.org/2001/XMLSchema# "> <head> <meta charset="utf-8" /><script type="text/javascript">(window.NREUM||(NREUM={})).init={ajax:{deny_list:["bam.nr-data.net"]}};(window.NREUM||(NREUM={})).loader_config={licenseKey:"37b7ccb661",applicationID:"1089704227"};;/*! For license information please see nr-loader-rum-1.274.0.min.js.LICENSE.txt */ (()=>{var e,t,r={8122:(e,t,r)=>{"use strict";r.d(t,{a:()=>i});var n=r(944);function i(e,t){try{if(!e||"object"!=typeof e)return(0,n.R)(3);if(!t||"object"!=typeof t)return(0,n.R)(4);const r=Object.create(Object.getPrototypeOf(t),Object.getOwnPropertyDescriptors(t)),o=0===Object.keys(r).length?e:r;for(let a in o)if(void 0!==e[a])try{if(null===e[a]){r[a]=null;continue}Array.isArray(e[a])&&Array.isArray(t[a])?r[a]=Array.from(new Set([...e[a],...t[a]])):"object"==typeof e[a]&&"object"==typeof t[a]?r[a]=i(e[a],t[a]):r[a]=e[a]}catch(e){(0,n.R)(1,e)}return r}catch(e){(0,n.R)(2,e)}}},2555:(e,t,r)=>{"use strict";r.d(t,{Vp:()=>c,fn:()=>s,x1:()=>u});var n=r(384),i=r(8122);const o={beacon:n.NT.beacon,errorBeacon:n.NT.errorBeacon,licenseKey:void 0,applicationID:void 0,sa:void 0,queueTime:void 0,applicationTime:void 0,ttGuid:void 0,user:void 0,account:void 0,product:void 0,extra:void 0,jsAttributes:{},userAttributes:void 0,atts:void 0,transactionName:void 0,tNamePlain:void 0},a={};function s(e){try{const t=c(e);return!!t.licenseKey&&!!t.errorBeacon&&!!t.applicationID}catch(e){return!1}}function c(e){if(!e)throw new Error("All info objects require an agent identifier!");if(!a[e])throw new Error("Info for ".concat(e," was never set"));return a[e]}function u(e,t){if(!e)throw new Error("All info objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.info=a[e])}},9417:(e,t,r)=>{"use strict";r.d(t,{D0:()=>g,gD:()=>h,xN:()=>p});var n=r(993);const i=e=>{if(!e||"string"!=typeof e)return!1;try{document.createDocumentFragment().querySelector(e)}catch{return!1}return!0};var o=r(2614),a=r(944),s=r(384),c=r(8122);const u="[data-nr-mask]",d=()=>{const e={mask_selector:"*",block_selector:"[data-nr-block]",mask_input_options:{color:!1,date:!1,"datetime-local":!1,email:!1,month:!1,number:!1,range:!1,search:!1,tel:!1,text:!1,time:!1,url:!1,week:!1,textarea:!1,select:!1,password:!0}};return{ajax:{deny_list:void 0,block_internal:!0,enabled:!0,harvestTimeSeconds:10,autoStart:!0},distributed_tracing:{enabled:void 0,exclude_newrelic_header:void 0,cors_use_newrelic_header:void 0,cors_use_tracecontext_headers:void 0,allowed_origins:void 0},feature_flags:[],generic_events:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},harvest:{tooManyRequestsDelay:60},jserrors:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},logging:{enabled:!0,harvestTimeSeconds:10,autoStart:!0,level:n.p_.INFO},metrics:{enabled:!0,autoStart:!0},obfuscate:void 0,page_action:{enabled:!0},page_view_event:{enabled:!0,autoStart:!0},page_view_timing:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},performance:{capture_marks:!1,capture_measures:!1},privacy:{cookies_enabled:!0},proxy:{assets:void 0,beacon:void 0},session:{expiresMs:o.wk,inactiveMs:o.BB},session_replay:{autoStart:!0,enabled:!1,harvestTimeSeconds:60,preload:!1,sampling_rate:10,error_sampling_rate:100,collect_fonts:!1,inline_images:!1,fix_stylesheets:!0,mask_all_inputs:!0,get mask_text_selector(){return e.mask_selector},set mask_text_selector(t){i(t)?e.mask_selector="".concat(t,",").concat(u):""===t||null===t?e.mask_selector=u:(0,a.R)(5,t)},get block_class(){return"nr-block"},get ignore_class(){return"nr-ignore"},get mask_text_class(){return"nr-mask"},get block_selector(){return e.block_selector},set block_selector(t){i(t)?e.block_selector+=",".concat(t):""!==t&&(0,a.R)(6,t)},get mask_input_options(){return e.mask_input_options},set mask_input_options(t){t&&"object"==typeof t?e.mask_input_options={...t,password:!0}:(0,a.R)(7,t)}},session_trace:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},soft_navigations:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},spa:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},ssl:void 0,user_actions:{enabled:!0}}},l={},f="All configuration objects require an agent identifier!";function g(e){if(!e)throw new Error(f);if(!l[e])throw new Error("Configuration for ".concat(e," was never set"));return l[e]}function p(e,t){if(!e)throw new Error(f);l[e]=(0,c.a)(t,d());const r=(0,s.nY)(e);r&&(r.init=l[e])}function h(e,t){if(!e)throw new Error(f);var r=g(e);if(r){for(var n=t.split("."),i=0;i<n.length-1;i++)if("object"!=typeof(r=r[n[i]]))return;r=r[n[n.length-1]]}return r}},3371:(e,t,r)=>{"use strict";r.d(t,{V:()=>f,f:()=>l});var n=r(8122),i=r(384),o=r(6154),a=r(9324);let s=0;const c={buildEnv:a.F3,distMethod:a.Xs,version:a.xv,originTime:o.WN},u={customTransaction:void 0,disabled:!1,isolatedBacklog:!1,loaderType:void 0,maxBytes:3e4,onerror:void 0,ptid:void 0,releaseIds:{},appMetadata:{},session:void 0,denyList:void 0,timeKeeper:void 0,obfuscator:void 0},d={};function l(e){if(!e)throw new Error("All runtime objects require an agent identifier!");if(!d[e])throw new Error("Runtime for ".concat(e," was never set"));return d[e]}function f(e,t){if(!e)throw new Error("All runtime objects require an agent identifier!");d[e]={...(0,n.a)(t,u),...c},Object.hasOwnProperty.call(d[e],"harvestCount")||Object.defineProperty(d[e],"harvestCount",{get:()=>++s});const r=(0,i.nY)(e);r&&(r.runtime=d[e])}},9324:(e,t,r)=>{"use strict";r.d(t,{F3:()=>i,Xs:()=>o,xv:()=>n});const n="1.274.0",i="PROD",o="CDN"},6154:(e,t,r)=>{"use strict";r.d(t,{OF:()=>c,RI:()=>i,WN:()=>d,bv:()=>o,gm:()=>a,mw:()=>s,sb:()=>u});var n=r(1863);const i="undefined"!=typeof window&&!!window.document,o="undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self.navigator instanceof WorkerNavigator||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis.navigator instanceof WorkerNavigator),a=i?window:"undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis),s=Boolean("hidden"===a?.document?.visibilityState),c=/iPad|iPhone|iPod/.test(a.navigator?.userAgent),u=c&&"undefined"==typeof SharedWorker,d=((()=>{const e=a.navigator?.userAgent?.match(/Firefox[/\s](\d+\.\d+)/);Array.isArray(e)&&e.length>=2&&e[1]})(),Date.now()-(0,n.t)())},1687:(e,t,r)=>{"use strict";r.d(t,{Ak:()=>c,Ze:()=>l,x3:()=>u});var n=r(7836),i=r(3606),o=r(860),a=r(2646);const s={};function c(e,t){const r={staged:!1,priority:o.P3[t]||0};d(e),s[e].get(t)||s[e].set(t,r)}function u(e,t){e&&s[e]&&(s[e].get(t)&&s[e].delete(t),g(e,t,!1),s[e].size&&f(e))}function d(e){if(!e)throw new Error("agentIdentifier required");s[e]||(s[e]=new Map)}function l(e="",t="feature",r=!1){if(d(e),!e||!s[e].get(t)||r)return g(e,t);s[e].get(t).staged=!0,f(e)}function f(e){const t=Array.from(s[e]);t.every((([e,t])=>t.staged))&&(t.sort(((e,t)=>e[1].priority-t[1].priority)),t.forEach((([t])=>{s[e].delete(t),g(e,t)})))}function g(e,t,r=!0){const o=e?n.ee.get(e):n.ee,s=i.i.handlers;if(!o.aborted&&o.backlog&&s){if(r){const e=o.backlog[t],r=s[t];if(r){for(let t=0;e&&t<e.length;++t)p(e[t],r);Object.entries(r).forEach((([e,t])=>{Object.values(t||{}).forEach((t=>{t[0]?.on&&t[0]?.context()instanceof a.y&&t[0].on(e,t[1])}))}))}}o.isolatedBacklog||delete s[t],o.backlog[t]=null,o.emit("drain-"+t,[])}}function p(e,t){var r=e[1];Object.values(t[r]||{}).forEach((t=>{var r=e[0];if(t[0]===r){var n=t[1],i=e[3],o=e[2];n.apply(i,o)}}))}},7836:(e,t,r)=>{"use strict";r.d(t,{P:()=>c,ee:()=>u});var n=r(384),i=r(8990),o=r(3371),a=r(2646),s=r(5607);const c="nr@context:".concat(s.W),u=function e(t,r){var n={},s={},d={},l=!1;try{l=16===r.length&&(0,o.f)(r).isolatedBacklog}catch(e){}var f={on:p,addEventListener:p,removeEventListener:function(e,t){var r=n[e];if(!r)return;for(var i=0;i<r.length;i++)r[i]===t&&r.splice(i,1)},emit:function(e,r,n,i,o){!1!==o&&(o=!0);if(u.aborted&&!i)return;t&&o&&t.emit(e,r,n);for(var a=g(n),c=h(e),d=c.length,l=0;l<d;l++)c[l].apply(a,r);var p=m()[s[e]];p&&p.push([f,e,r,a]);return a},get:v,listeners:h,context:g,buffer:function(e,t){const r=m();if(t=t||"feature",f.aborted)return;Object.entries(e||{}).forEach((([e,n])=>{s[n]=t,t in r||(r[t]=[])}))},abort:function(){f._aborted=!0,Object.keys(f.backlog).forEach((e=>{delete f.backlog[e]}))},isBuffering:function(e){return!!m()[s[e]]},debugId:r,backlog:l?{}:t&&"object"==typeof t.backlog?t.backlog:{},isolatedBacklog:l};return Object.defineProperty(f,"aborted",{get:()=>{let e=f._aborted||!1;return e||(t&&(e=t.aborted),e)}}),f;function g(e){return e&&e instanceof a.y?e:e?(0,i.I)(e,c,(()=>new a.y(c))):new a.y(c)}function p(e,t){n[e]=h(e).concat(t)}function h(e){return n[e]||[]}function v(t){return d[t]=d[t]||e(f,t)}function m(){return f.backlog}}(void 0,"globalEE"),d=(0,n.Zm)();d.ee||(d.ee=u)},2646:(e,t,r)=>{"use strict";r.d(t,{y:()=>n});class n{constructor(e){this.contextId=e}}},9908:(e,t,r)=>{"use strict";r.d(t,{d:()=>n,p:()=>i});var n=r(7836).ee.get("handle");function i(e,t,r,i,o){o?(o.buffer([e],i),o.emit(e,t,r)):(n.buffer([e],i),n.emit(e,t,r))}},3606:(e,t,r)=>{"use strict";r.d(t,{i:()=>o});var n=r(9908);o.on=a;var i=o.handlers={};function o(e,t,r,o){a(o||n.d,i,e,t,r)}function a(e,t,r,i,o){o||(o="feature"),e||(e=n.d);var a=t[o]=t[o]||{};(a[r]=a[r]||[]).push([e,i])}},3878:(e,t,r)=>{"use strict";function n(e,t){return{capture:e,passive:!1,signal:t}}function i(e,t,r=!1,i){window.addEventListener(e,t,n(r,i))}function o(e,t,r=!1,i){document.addEventListener(e,t,n(r,i))}r.d(t,{DD:()=>o,jT:()=>n,sp:()=>i})},5607:(e,t,r)=>{"use strict";r.d(t,{W:()=>n});const n=(0,r(9566).bz)()},9566:(e,t,r)=>{"use strict";r.d(t,{LA:()=>s,bz:()=>a});var n=r(6154);const i="xxxxxxxx-xxxx-4xxx-yxxx-xxxxxxxxxxxx";function o(e,t){return e?15&e[t]:16*Math.random()|0}function a(){const e=n.gm?.crypto||n.gm?.msCrypto;let t,r=0;return e&&e.getRandomValues&&(t=e.getRandomValues(new Uint8Array(30))),i.split("").map((e=>"x"===e?o(t,r++).toString(16):"y"===e?(3&o()|8).toString(16):e)).join("")}function s(e){const t=n.gm?.crypto||n.gm?.msCrypto;let r,i=0;t&&t.getRandomValues&&(r=t.getRandomValues(new Uint8Array(e)));const a=[];for(var s=0;s<e;s++)a.push(o(r,i++).toString(16));return a.join("")}},2614:(e,t,r)=>{"use strict";r.d(t,{BB:()=>a,H3:()=>n,g:()=>u,iL:()=>c,tS:()=>s,uh:()=>i,wk:()=>o});const n="NRBA",i="SESSION",o=144e5,a=18e5,s={STARTED:"session-started",PAUSE:"session-pause",RESET:"session-reset",RESUME:"session-resume",UPDATE:"session-update"},c={SAME_TAB:"same-tab",CROSS_TAB:"cross-tab"},u={OFF:0,FULL:1,ERROR:2}},1863:(e,t,r)=>{"use strict";function n(){return Math.floor(performance.now())}r.d(t,{t:()=>n})},944:(e,t,r)=>{"use strict";function n(e,t){"function"==typeof console.debug&&console.debug("New Relic Warning: https://github.com/newrelic/newrelic-browser-agent/blob/main/docs/warning-codes.md#".concat(e),t)}r.d(t,{R:()=>n})},5284:(e,t,r)=>{"use strict";r.d(t,{t:()=>c,B:()=>s});var n=r(7836),i=r(6154);const o="newrelic";const a=new Set,s={};function c(e,t){const r=n.ee.get(t);s[t]??={},e&&"object"==typeof e&&(a.has(t)||(r.emit("rumresp",[e]),s[t]=e,a.add(t),function(e={}){try{i.gm.dispatchEvent(new CustomEvent(o,{detail:e}))}catch(e){}}({loaded:!0})))}},8990:(e,t,r)=>{"use strict";r.d(t,{I:()=>i});var n=Object.prototype.hasOwnProperty;function i(e,t,r){if(n.call(e,t))return e[t];var i=r();if(Object.defineProperty&&Object.keys)try{return Object.defineProperty(e,t,{value:i,writable:!0,enumerable:!1}),i}catch(e){}return e[t]=i,i}},6389:(e,t,r)=>{"use strict";function n(e,t=500,r={}){const n=r?.leading||!1;let i;return(...r)=>{n&&void 0===i&&(e.apply(this,r),i=setTimeout((()=>{i=clearTimeout(i)}),t)),n||(clearTimeout(i),i=setTimeout((()=>{e.apply(this,r)}),t))}}function i(e){let t=!1;return(...r)=>{t||(t=!0,e.apply(this,r))}}r.d(t,{J:()=>i,s:()=>n})},5289:(e,t,r)=>{"use strict";r.d(t,{GG:()=>o,sB:()=>a});var n=r(3878);function i(){return"undefined"==typeof document||"complete"===document.readyState}function o(e,t){if(i())return e();(0,n.sp)("load",e,t)}function a(e){if(i())return e();(0,n.DD)("DOMContentLoaded",e)}},384:(e,t,r)=>{"use strict";r.d(t,{NT:()=>o,US:()=>d,Zm:()=>a,bQ:()=>c,dV:()=>s,nY:()=>u,pV:()=>l});var n=r(6154),i=r(1863);const o={beacon:"bam.nr-data.net",errorBeacon:"bam.nr-data.net"};function a(){return n.gm.NREUM||(n.gm.NREUM={}),void 0===n.gm.newrelic&&(n.gm.newrelic=n.gm.NREUM),n.gm.NREUM}function s(){let e=a();return e.o||(e.o={ST:n.gm.setTimeout,SI:n.gm.setImmediate,CT:n.gm.clearTimeout,XHR:n.gm.XMLHttpRequest,REQ:n.gm.Request,EV:n.gm.Event,PR:n.gm.Promise,MO:n.gm.MutationObserver,FETCH:n.gm.fetch,WS:n.gm.WebSocket}),e}function c(e,t){let r=a();r.initializedAgents??={},t.initializedAt={ms:(0,i.t)(),date:new Date},r.initializedAgents[e]=t}function u(e){let t=a();return t.initializedAgents?.[e]}function d(e,t){a()[e]=t}function l(){return function(){let e=a();const t=e.info||{};e.info={beacon:o.beacon,errorBeacon:o.errorBeacon,...t}}(),function(){let e=a();const t=e.init||{};e.init={...t}}(),s(),function(){let e=a();const t=e.loader_config||{};e.loader_config={...t}}(),a()}},2843:(e,t,r)=>{"use strict";r.d(t,{u:()=>i});var n=r(3878);function i(e,t=!1,r,i){(0,n.DD)("visibilitychange",(function(){if(t)return void("hidden"===document.visibilityState&&e());e(document.visibilityState)}),r,i)}},3434:(e,t,r)=>{"use strict";r.d(t,{YM:()=>c});var n=r(7836),i=r(5607);const o="nr@original:".concat(i.W);var a=Object.prototype.hasOwnProperty,s=!1;function c(e,t){return e||(e=n.ee),r.inPlace=function(e,t,n,i,o){n||(n="");const a="-"===n.charAt(0);for(let s=0;s<t.length;s++){const c=t[s],u=e[c];d(u)||(e[c]=r(u,a?c+n:n,i,c,o))}},r.flag=o,r;function r(t,r,n,s,c){return d(t)?t:(r||(r=""),nrWrapper[o]=t,function(e,t,r){if(Object.defineProperty&&Object.keys)try{return Object.keys(e).forEach((function(r){Object.defineProperty(t,r,{get:function(){return e[r]},set:function(t){return e[r]=t,t}})})),t}catch(e){u([e],r)}for(var n in e)a.call(e,n)&&(t[n]=e[n])}(t,nrWrapper,e),nrWrapper);function nrWrapper(){var o,a,d,l;try{a=this,o=[...arguments],d="function"==typeof n?n(o,a):n||{}}catch(t){u([t,"",[o,a,s],d],e)}i(r+"start",[o,a,s],d,c);try{return l=t.apply(a,o)}catch(e){throw i(r+"err",[o,a,e],d,c),e}finally{i(r+"end",[o,a,l],d,c)}}}function i(r,n,i,o){if(!s||t){var a=s;s=!0;try{e.emit(r,n,i,t,o)}catch(t){u([t,r,n,i],e)}s=a}}}function u(e,t){t||(t=n.ee);try{t.emit("internal-error",e)}catch(e){}}function d(e){return!(e&&"function"==typeof e&&e.apply&&!e[o])}},993:(e,t,r)=>{"use strict";r.d(t,{ET:()=>o,p_:()=>i});var n=r(860);const i={ERROR:"ERROR",WARN:"WARN",INFO:"INFO",DEBUG:"DEBUG",TRACE:"TRACE"},o="log";n.K7.logging},3969:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,XG:()=>s,rs:()=>i,xV:()=>a,z_:()=>o});const n=r(860).K7.metrics,i="sm",o="cm",a="storeSupportabilityMetrics",s="storeEventMetrics"},6630:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewEvent},782:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewTiming},6344:(e,t,r)=>{"use strict";r.d(t,{G4:()=>i});var n=r(2614);r(860).K7.sessionReplay;const i={RECORD:"recordReplay",PAUSE:"pauseReplay",REPLAY_RUNNING:"replayRunning",ERROR_DURING_REPLAY:"errorDuringReplay"};n.g.ERROR,n.g.FULL,n.g.OFF},4234:(e,t,r)=>{"use strict";r.d(t,{W:()=>o});var n=r(7836),i=r(1687);class o{constructor(e,t){this.agentIdentifier=e,this.ee=n.ee.get(e),this.featureName=t,this.blocked=!1}deregisterDrain(){(0,i.x3)(this.agentIdentifier,this.featureName)}}},7603:(e,t,r)=>{"use strict";r.d(t,{j:()=>P});var n=r(860),i=r(2555),o=r(3371),a=r(9908),s=r(7836),c=r(1687),u=r(5289),d=r(6154),l=r(944),f=r(3969),g=r(384),p=r(6344);const h=["setErrorHandler","finished","addToTrace","addRelease","addPageAction","setCurrentRouteName","setPageViewName","setCustomAttribute","interaction","noticeError","setUserId","setApplicationVersion","start",p.G4.RECORD,p.G4.PAUSE,"log","wrapLogger"],v=["setErrorHandler","finished","addToTrace","addRelease"];var m=r(1863),b=r(2614),y=r(993);var w=r(2646),A=r(3434);function R(e,t,r,n){if("object"!=typeof t||!t||"string"!=typeof r||!r||"function"!=typeof t[r])return(0,l.R)(29);const i=function(e){return(e||s.ee).get("logger")}(e),o=(0,A.YM)(i),a=new w.y(s.P);return a.level=n.level,a.customAttributes=n.customAttributes,o.inPlace(t,[r],"wrap-logger-",a),i}function E(){const e=(0,g.pV)();h.forEach((t=>{e[t]=(...r)=>function(t,...r){let n=[];return Object.values(e.initializedAgents).forEach((e=>{e&&e.api?e.exposed&&e.api[t]&&n.push(e.api[t](...r)):(0,l.R)(38,t)})),n.length>1?n:n[0]}(t,...r)}))}const x={};function _(e,t,g=!1){t||(0,c.Ak)(e,"api");const h={};var w=s.ee.get(e),A=w.get("tracer");x[e]=b.g.OFF,w.on(p.G4.REPLAY_RUNNING,(t=>{x[e]=t}));var E="api-",_=E+"ixn-";function N(t,r,n,o){const a=(0,i.Vp)(e);return null===r?delete a.jsAttributes[t]:(0,i.x1)(e,{...a,jsAttributes:{...a.jsAttributes,[t]:r}}),j(E,n,!0,o||null===r?"session":void 0)(t,r)}function T(){}h.log=function(e,{customAttributes:t={},level:r=y.p_.INFO}={}){(0,a.p)(f.xV,["API/log/called"],void 0,n.K7.metrics,w),function(e,t,r={},i=y.p_.INFO){(0,a.p)(f.xV,["API/logging/".concat(i.toLowerCase(),"/called")],void 0,n.K7.metrics,e),(0,a.p)(y.ET,[(0,m.t)(),t,r,i],void 0,n.K7.logging,e)}(w,e,t,r)},h.wrapLogger=(e,t,{customAttributes:r={},level:i=y.p_.INFO}={})=>{(0,a.p)(f.xV,["API/wrapLogger/called"],void 0,n.K7.metrics,w),R(w,e,t,{customAttributes:r,level:i})},v.forEach((e=>{h[e]=j(E,e,!0,"api")})),h.addPageAction=j(E,"addPageAction",!0,n.K7.genericEvents),h.setPageViewName=function(t,r){if("string"==typeof t)return"/"!==t.charAt(0)&&(t="/"+t),(0,o.f)(e).customTransaction=(r||"http://custom.transaction")+t,j(E,"setPageViewName",!0)()},h.setCustomAttribute=function(e,t,r=!1){if("string"==typeof e){if(["string","number","boolean"].includes(typeof t)||null===t)return N(e,t,"setCustomAttribute",r);(0,l.R)(40,typeof t)}else(0,l.R)(39,typeof e)},h.setUserId=function(e){if("string"==typeof e||null===e)return N("enduser.id",e,"setUserId",!0);(0,l.R)(41,typeof e)},h.setApplicationVersion=function(e){if("string"==typeof e||null===e)return N("application.version",e,"setApplicationVersion",!1);(0,l.R)(42,typeof e)},h.start=()=>{try{(0,a.p)(f.xV,["API/start/called"],void 0,n.K7.metrics,w),w.emit("manual-start-all")}catch(e){(0,l.R)(23,e)}},h[p.G4.RECORD]=function(){(0,a.p)(f.xV,["API/recordReplay/called"],void 0,n.K7.metrics,w),(0,a.p)(p.G4.RECORD,[],void 0,n.K7.sessionReplay,w)},h[p.G4.PAUSE]=function(){(0,a.p)(f.xV,["API/pauseReplay/called"],void 0,n.K7.metrics,w),(0,a.p)(p.G4.PAUSE,[],void 0,n.K7.sessionReplay,w)},h.interaction=function(e){return(new T).get("object"==typeof e?e:{})};const S=T.prototype={createTracer:function(e,t){var r={},i=this,o="function"==typeof t;return(0,a.p)(f.xV,["API/createTracer/called"],void 0,n.K7.metrics,w),g||(0,a.p)(_+"tracer",[(0,m.t)(),e,r],i,n.K7.spa,w),function(){if(A.emit((o?"":"no-")+"fn-start",[(0,m.t)(),i,o],r),o)try{return t.apply(this,arguments)}catch(e){const t="string"==typeof e?new Error(e):e;throw A.emit("fn-err",[arguments,this,t],r),t}finally{A.emit("fn-end",[(0,m.t)()],r)}}}};function j(e,t,r,i){return function(){return(0,a.p)(f.xV,["API/"+t+"/called"],void 0,n.K7.metrics,w),i&&(0,a.p)(e+t,[(0,m.t)(),...arguments],r?null:this,i,w),r?void 0:this}}function k(){r.e(296).then(r.bind(r,8778)).then((({setAPI:t})=>{t(e),(0,c.Ze)(e,"api")})).catch((e=>{(0,l.R)(27,e),w.abort()}))}return["actionText","setName","setAttribute","save","ignore","onEnd","getContext","end","get"].forEach((e=>{S[e]=j(_,e,void 0,g?n.K7.softNav:n.K7.spa)})),h.setCurrentRouteName=g?j(_,"routeName",void 0,n.K7.softNav):j(E,"routeName",!0,n.K7.spa),h.noticeError=function(t,r){"string"==typeof t&&(t=new Error(t)),(0,a.p)(f.xV,["API/noticeError/called"],void 0,n.K7.metrics,w),(0,a.p)("err",[t,(0,m.t)(),!1,r,!!x[e]],void 0,n.K7.jserrors,w)},d.RI?(0,u.GG)((()=>k()),!0):k(),h}var N=r(9417),T=r(8122);const S={accountID:void 0,trustKey:void 0,agentID:void 0,licenseKey:void 0,applicationID:void 0,xpid:void 0},j={};var k=r(5284);const I=e=>{const t=e.startsWith("http");e+="/",r.p=t?e:"https://"+e};let O=!1;function P(e,t={},r,n){let{init:a,info:c,loader_config:u,runtime:l={},exposed:f=!0}=t;l.loaderType=r;const p=(0,g.pV)();c||(a=p.init,c=p.info,u=p.loader_config),(0,N.xN)(e.agentIdentifier,a||{}),function(e,t){if(!e)throw new Error("All loader-config objects require an agent identifier!");j[e]=(0,T.a)(t,S);const r=(0,g.nY)(e);r&&(r.loader_config=j[e])}(e.agentIdentifier,u||{}),c.jsAttributes??={},d.bv&&(c.jsAttributes.isWorker=!0),(0,i.x1)(e.agentIdentifier,c);const h=(0,N.D0)(e.agentIdentifier),v=[c.beacon,c.errorBeacon];O||(h.proxy.assets&&(I(h.proxy.assets),v.push(h.proxy.assets)),h.proxy.beacon&&v.push(h.proxy.beacon),E(),(0,g.US)("activatedFeatures",k.B),e.runSoftNavOverSpa&&=!0===h.soft_navigations.enabled&&h.feature_flags.includes("soft_nav")),l.denyList=[...h.ajax.deny_list||[],...h.ajax.block_internal?v:[]],l.ptid=e.agentIdentifier,(0,o.V)(e.agentIdentifier,l),e.ee=s.ee.get(e.agentIdentifier),void 0===e.api&&(e.api=_(e.agentIdentifier,n,e.runSoftNavOverSpa)),void 0===e.exposed&&(e.exposed=f),O=!0}},8374:(e,t,r)=>{r.nc=(()=>{try{return document?.currentScript?.nonce}catch(e){}return""})()},860:(e,t,r)=>{"use strict";r.d(t,{$J:()=>o,K7:()=>n,P3:()=>i});const n={ajax:"ajax",genericEvents:"generic_events",jserrors:"jserrors",logging:"logging",metrics:"metrics",pageAction:"page_action",pageViewEvent:"page_view_event",pageViewTiming:"page_view_timing",sessionReplay:"session_replay",sessionTrace:"session_trace",softNav:"soft_navigations",spa:"spa"},i={[n.pageViewEvent]:1,[n.pageViewTiming]:2,[n.metrics]:3,[n.jserrors]:4,[n.spa]:5,[n.ajax]:6,[n.sessionTrace]:7,[n.softNav]:8,[n.sessionReplay]:9,[n.logging]:10,[n.genericEvents]:11},o={[n.pageViewTiming]:"events",[n.ajax]:"events",[n.spa]:"events",[n.softNav]:"events",[n.metrics]:"jserrors",[n.jserrors]:"jserrors",[n.sessionTrace]:"browser/blobs",[n.sessionReplay]:"browser/blobs",[n.logging]:"browser/logs",[n.genericEvents]:"ins"}}},n={};function i(e){var t=n[e];if(void 0!==t)return t.exports;var o=n[e]={exports:{}};return r[e](o,o.exports,i),o.exports}i.m=r,i.d=(e,t)=>{for(var r in t)i.o(t,r)&&!i.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})},i.f={},i.e=e=>Promise.all(Object.keys(i.f).reduce(((t,r)=>(i.f[r](e,t),t)),[])),i.u=e=>"nr-rum-1.274.0.min.js",i.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),e={},t="NRBA-1.274.0.PROD:",i.l=(r,n,o,a)=>{if(e[r])e[r].push(n);else{var s,c;if(void 0!==o)for(var u=document.getElementsByTagName("script"),d=0;d<u.length;d++){var l=u[d];if(l.getAttribute("src")==r||l.getAttribute("data-webpack")==t+o){s=l;break}}if(!s){c=!0;var f={296:"sha512-gkYkZDAwQ9PwaDXs2YM+rNIdRej1Ac1mupWobRJ8eahQcXz6/sunGZCKklrzi5kWxhOGRZr2tn0rEKuLTXzfAA=="};(s=document.createElement("script")).charset="utf-8",s.timeout=120,i.nc&&s.setAttribute("nonce",i.nc),s.setAttribute("data-webpack",t+o),s.src=r,0!==s.src.indexOf(window.location.origin+"/")&&(s.crossOrigin="anonymous"),f[a]&&(s.integrity=f[a])}e[r]=[n];var g=(t,n)=>{s.onerror=s.onload=null,clearTimeout(p);var i=e[r];if(delete e[r],s.parentNode&&s.parentNode.removeChild(s),i&&i.forEach((e=>e(n))),t)return t(n)},p=setTimeout(g.bind(null,void 0,{type:"timeout",target:s}),12e4);s.onerror=g.bind(null,s.onerror),s.onload=g.bind(null,s.onload),c&&document.head.appendChild(s)}},i.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})},i.p="https://js-agent.newrelic.com/",(()=>{var e={840:0,374:0};i.f.j=(t,r)=>{var n=i.o(e,t)?e[t]:void 0;if(0!==n)if(n)r.push(n[2]);else{var o=new Promise(((r,i)=>n=e[t]=[r,i]));r.push(n[2]=o);var a=i.p+i.u(t),s=new Error;i.l(a,(r=>{if(i.o(e,t)&&(0!==(n=e[t])&&(e[t]=void 0),n)){var o=r&&("load"===r.type?"missing":r.type),a=r&&r.target&&r.target.src;s.message="Loading chunk "+t+" failed.\n("+o+": "+a+")",s.name="ChunkLoadError",s.type=o,s.request=a,n[1](s)}}),"chunk-"+t,t)}};var t=(t,r)=>{var n,o,[a,s,c]=r,u=0;if(a.some((t=>0!==e[t]))){for(n in s)i.o(s,n)&&(i.m[n]=s[n]);if(c)c(i)}for(t&&t(r);u<a.length;u++)o=a[u],i.o(e,o)&&e[o]&&e[o][0](),e[o]=0},r=self["webpackChunk:NRBA-1.274.0.PROD"]=self["webpackChunk:NRBA-1.274.0.PROD"]||[];r.forEach(t.bind(null,0)),r.push=t.bind(null,r.push.bind(r))})(),(()=>{"use strict";i(8374);var e=i(944),t=i(6344),r=i(9566);class n{agentIdentifier;constructor(e=(0,r.LA)(16)){this.agentIdentifier=e}#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}addPageAction(e,t){return this.#e("addPageAction",e,t)}setPageViewName(e,t){return this.#e("setPageViewName",e,t)}setCustomAttribute(e,t,r){return this.#e("setCustomAttribute",e,t,r)}noticeError(e,t){return this.#e("noticeError",e,t)}setUserId(e){return this.#e("setUserId",e)}setApplicationVersion(e){return this.#e("setApplicationVersion",e)}setErrorHandler(e){return this.#e("setErrorHandler",e)}addRelease(e,t){return this.#e("addRelease",e,t)}log(e,t){return this.#e("log",e,t)}}class o extends n{#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}start(){return this.#e("start")}finished(e){return this.#e("finished",e)}recordReplay(){return this.#e(t.G4.RECORD)}pauseReplay(){return this.#e(t.G4.PAUSE)}addToTrace(e){return this.#e("addToTrace",e)}setCurrentRouteName(e){return this.#e("setCurrentRouteName",e)}interaction(){return this.#e("interaction")}wrapLogger(e,t,r){return this.#e("wrapLogger",e,t,r)}}var a=i(860),s=i(9417);const c=Object.values(a.K7);function u(e){const t={};return c.forEach((r=>{t[r]=function(e,t){return!0===(0,s.gD)(t,"".concat(e,".enabled"))}(r,e)})),t}var d=i(7603);var l=i(1687),f=i(4234),g=i(5289),p=i(6154),h=i(384);const v=e=>p.RI&&!0===(0,s.gD)(e,"privacy.cookies_enabled");function m(e){return!!(0,h.dV)().o.MO&&v(e)&&!0===(0,s.gD)(e,"session_trace.enabled")}var b=i(6389);class y extends f.W{constructor(e,t,r=!0){super(e.agentIdentifier,t),this.auto=r,this.abortHandler=void 0,this.featAggregate=void 0,this.onAggregateImported=void 0,!1===e.init[this.featureName].autoStart&&(this.auto=!1),this.auto?(0,l.Ak)(e.agentIdentifier,t):this.ee.on("manual-start-all",(0,b.J)((()=>{(0,l.Ak)(e.agentIdentifier,this.featureName),this.auto=!0,this.importAggregator(e)})))}importAggregator(t,r={}){if(this.featAggregate||!this.auto)return;let n;this.onAggregateImported=new Promise((e=>{n=e}));const o=async()=>{let o;try{if(v(this.agentIdentifier)){const{setupAgentSession:e}=await i.e(296).then(i.bind(i,3861));o=e(t)}}catch(t){(0,e.R)(20,t),this.ee.emit("internal-error",[t]),this.featureName===a.K7.sessionReplay&&this.abortHandler?.()}try{if(t.sharedAggregator)await t.sharedAggregator;else{t.sharedAggregator=i.e(296).then(i.bind(i,9337));const{EventAggregator:e}=await t.sharedAggregator;t.sharedAggregator=new e}if(!this.#t(this.featureName,o))return(0,l.Ze)(this.agentIdentifier,this.featureName),void n(!1);const{lazyFeatureLoader:e}=await i.e(296).then(i.bind(i,6103)),{Aggregate:a}=await e(this.featureName,"aggregate");this.featAggregate=new a(t,r),n(!0)}catch(t){(0,e.R)(34,t),this.abortHandler?.(),(0,l.Ze)(this.agentIdentifier,this.featureName,!0),n(!1),this.ee&&this.ee.abort()}};p.RI?(0,g.GG)((()=>o()),!0):o()}#t(e,t){switch(e){case a.K7.sessionReplay:return m(this.agentIdentifier)&&!!t;case a.K7.sessionTrace:return!!t;default:return!0}}}var w=i(6630);class A extends y{static featureName=w.T;constructor(e,t=!0){super(e,w.T,t),this.importAggregator(e)}}var R=i(9908),E=i(2843),x=i(3878),_=i(782),N=i(1863);class T extends y{static featureName=_.T;constructor(e,t=!0){super(e,_.T,t),p.RI&&((0,E.u)((()=>(0,R.p)("docHidden",[(0,N.t)()],void 0,_.T,this.ee)),!0),(0,x.sp)("pagehide",(()=>(0,R.p)("winPagehide",[(0,N.t)()],void 0,_.T,this.ee))),this.importAggregator(e))}}var S=i(3969);class j extends y{static featureName=S.TZ;constructor(e,t=!0){super(e,S.TZ,t),this.importAggregator(e)}}new class extends o{constructor(t,r){super(r),p.gm?(this.features={},(0,h.bQ)(this.agentIdentifier,this),this.desiredFeatures=new Set(t.features||[]),this.desiredFeatures.add(A),this.runSoftNavOverSpa=[...this.desiredFeatures].some((e=>e.featureName===a.K7.softNav)),(0,d.j)(this,t,t.loaderType||"agent"),this.run()):(0,e.R)(21)}get config(){return{info:this.info,init:this.init,loader_config:this.loader_config,runtime:this.runtime}}run(){try{const t=u(this.agentIdentifier),r=[...this.desiredFeatures];r.sort(((e,t)=>a.P3[e.featureName]-a.P3[t.featureName])),r.forEach((r=>{if(!t[r.featureName]&&r.featureName!==a.K7.pageViewEvent)return;if(this.runSoftNavOverSpa&&r.featureName===a.K7.spa)return;if(!this.runSoftNavOverSpa&&r.featureName===a.K7.softNav)return;const n=function(e){switch(e){case a.K7.ajax:return[a.K7.jserrors];case a.K7.sessionTrace:return[a.K7.ajax,a.K7.pageViewEvent];case a.K7.sessionReplay:return[a.K7.sessionTrace];case a.K7.pageViewTiming:return[a.K7.pageViewEvent];default:return[]}}(r.featureName).filter((e=>!(e in this.features)));n.length>0&&(0,e.R)(36,{targetFeature:r.featureName,missingDependencies:n}),this.features[r.featureName]=new r(this)}))}catch(t){(0,e.R)(22,t);for(const e in this.features)this.features[e].abortHandler?.();const r=(0,h.Zm)();delete r.initializedAgents[this.agentIdentifier]?.api,delete r.initializedAgents[this.agentIdentifier]?.features,delete this.sharedAggregator;return r.ee.get(this.agentIdentifier).abort(),!1}}}({features:[A,T,j],loaderType:"lite"})})()})();</script> <noscript><style>form.antibot * :not(.antibot-message) { display: none !important; }</style> </noscript><script async src="https://www.googletagmanager.com/gtag/js?id=G-HEQ0YF2VYL"></script> <script>window.dataLayer = window.dataLayer || [];function gtag(){dataLayer.push(arguments)};gtag("js", new Date());gtag("set", "developer_id.dMDhkMT", true);gtag('set', {'cookie_flags': 'SameSite=None;Secure', 'cookie_domain': 'www.nist.gov'});gtag("config", "G-HEQ0YF2VYL", {"groups":"default","page_placeholder":"PLACEHOLDER_page_location","link_attribution":true,"allow_ad_personalization_signals":false});gtag("config", "UA-33523145-1", {"groups":"default","anonymize_ip":true,"page_placeholder":"PLACEHOLDER_page_path","link_attribution":true,"allow_ad_personalization_signals":false,"custom_map":{"dimension2":"node_title","dimension3":"node_id","dimension7":"content_type"}});gtag("config", "G-CSLL4ZEK4L", {"groups":"default","page_placeholder":"PLACEHOLDER_page_location","link_attribution":true,"allow_ad_personalization_signals":false});gtag("event", "custom", {"node_title":"Health","node_id":"1079336","content_type":"Topic Landing Page"});</script> <meta name="description" content="NIST provides measurement assurance for biomedical stakeholders through the development of measurement tools for medical devices, clinical diagnostics, imaging tools and the characterization of biotherapeutics." /> <link rel="canonical" href="https://www.nist.gov/health" /> <link rel="shortlink" href="https://www.nist.gov/node/1079336" /> <meta name="citation_title" content="Health | NIST" /> <meta property="og:site_name" content="NIST" /> <meta property="og:type" content="Article" /> <meta property="og:url" content="https://www.nist.gov/health" /> <meta property="og:title" content="Health" /> <meta property="og:description" content="NIST provides measurement assurance for biomedical stakeholders through the development of measurement tools for medical devices, clinical diagnostics, imaging tools and the characterization of biotherapeutics." /> <meta property="og:image" content="https://www.nist.gov/sites/default/files/styles/social/public/images/2018/10/18/healthy_human_t_cell_blog_image.jpg?itok=_THfIz71" /> <meta property="og:image:width" content="1884" /> <meta property="og:image:height" content="1884" /> <meta property="og:image:alt" content="black background. Bright blue t-cell" /> <meta property="article:published_time" content="2016-06-30T13:50-04:00" /> <meta property="article:modified_time" content="2024-09-18T09:18-04:00" /> <meta name="dcterms.title" content="Health" /> <meta name="dcterms.description" content="NIST provides measurement assurance for biomedical stakeholders through the development of measurement tools for medical devices, clinical diagnostics, imaging tools and the characterization of biotherapeutics." /> <meta name="dcterms.date" content="2016-06-30T13:50-04:00" /> <meta name="dcterms.type" content="text" /> <meta name="dcterms.format" content="text/html" /> <meta name="dcterms.identifier" content="https://www.nist.gov/health" /> <meta name="dcterms.source" content="NIST" /> <meta name="dcterms.created" content="2016-06-30T13:50-04:00" /> <meta name="dcterms.modified" content="2024-09-18T09:18-04:00" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:description" content="NIST provides measurement assurance for biomedical stakeholders through the development of measurement tools for medical devices, clinical diagnostics, imaging tools and the characterization of biotherapeutics." /> <meta name="twitter:site" content="NIST" /> <meta name="twitter:title" content="Health" /> <meta name="google-site-verification" content="QMu0ODkER3rN5hLcMLqNVf7e3bkjYsNLTuhqfH48jCA" /> <meta name="Generator" content="Drupal 10 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <meta name="nist_search_modified" class="elastic" content="2024-09-18T09:18:00-04:00" /> <meta name="nist_search_bundle" class="elastic" content="topic_landing_page" /> <link rel="icon" href="/themes/custom/nist_www/favicon.ico" type="image/vnd.microsoft.icon" /> <title>Health | NIST</title> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_wuR8ZwMFh0__FFo3R4zfCcvSs-_yPHYXP8MHmoyxi0Q.css?delta=0&language=en&theme=nist_www&include=eJx1TwGOwyAM-xBXnoRCySC3lDAC6-33R3udWk06CaHYjmzHw3x3TcYr1p-z-1bj_5FolmyiSGR0kIFfjWa1n4TJpM3daHBB1swCwbU6bChHG-FPVmpIS6nyRPtJbBV2riVccCQLe6hukWADKfhhzJTvRl_acBkNFfd9G1k88HX-OqxsQghY39Ct63rdvuBtBX_aFmBD7QV4OqApUCFWKEnfyslMPZfumTRhME_CVe3-T6N156MfPjqwS0gxtTN3obnKdv4vXRCeuQ" /> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_fa1651ZoYZuqCbaIzCHaJC0W6fhWSS6nO014ZFCGwPo.css?delta=1&language=en&theme=nist_www&include=eJx1TwGOwyAM-xBXnoRCySC3lDAC6-33R3udWk06CaHYjmzHw3x3TcYr1p-z-1bj_5FolmyiSGR0kIFfjWa1n4TJpM3daHBB1swCwbU6bChHG-FPVmpIS6nyRPtJbBV2riVccCQLe6hukWADKfhhzJTvRl_acBkNFfd9G1k88HX-OqxsQghY39Ct63rdvuBtBX_aFmBD7QV4OqApUCFWKEnfyslMPZfumTRhME_CVe3-T6N156MfPjqwS0gxtTN3obnKdv4vXRCeuQ" /> <link rel="stylesheet" media="print" href="/sites/default/files/css/css_9Coyc_d7BWI3xLJk5PwpQTcYxaLUNGsq-07t6YSu-vo.css?delta=2&language=en&theme=nist_www&include=eJx1TwGOwyAM-xBXnoRCySC3lDAC6-33R3udWk06CaHYjmzHw3x3TcYr1p-z-1bj_5FolmyiSGR0kIFfjWa1n4TJpM3daHBB1swCwbU6bChHG-FPVmpIS6nyRPtJbBV2riVccCQLe6hukWADKfhhzJTvRl_acBkNFfd9G1k88HX-OqxsQghY39Ct63rdvuBtBX_aFmBD7QV4OqApUCFWKEnfyslMPZfumTRhME_CVe3-T6N156MfPjqwS0gxtTN3obnKdv4vXRCeuQ" /> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_Kz2bG7r0MVPRglAGQYamzQ0UEfAz0mtCbLJIj9V8n6A.css?delta=3&language=en&theme=nist_www&include=eJx1TwGOwyAM-xBXnoRCySC3lDAC6-33R3udWk06CaHYjmzHw3x3TcYr1p-z-1bj_5FolmyiSGR0kIFfjWa1n4TJpM3daHBB1swCwbU6bChHG-FPVmpIS6nyRPtJbBV2riVccCQLe6hukWADKfhhzJTvRl_acBkNFfd9G1k88HX-OqxsQghY39Ct63rdvuBtBX_aFmBD7QV4OqApUCFWKEnfyslMPZfumTRhME_CVe3-T6N156MfPjqwS0gxtTN3obnKdv4vXRCeuQ" /> <script src="/sites/default/files/js/js_JtHi3E9mRUm2eZxqQyZvyq93aaxzrwZcMhpD2hb_Uvk.js?scope=header&delta=0&language=en&theme=nist_www&include=eJx1TwGOwyAM-xBXnoRCySC3lDAC6-33R3udWk06CaHYjmzHw3x3TcYr1p-z-1bj_5FolmyiSGR0kIFfjWa1n4TJpM3daHBB1swCwbU6bChHG-FPVmpIS6nyRPtJbBV2riVccCQLe6hukWADKfhhzJTvRl_acBkNFfd9G1k88HX-OqxsQghY39Ct63rdvuBtBX_aFmBD7QV4OqApUCFWKEnfyslMPZfumTRhME_CVe3-T6N156MfPjqwS0gxtTN3obnKdv4vXRCeuQ"></script> </head> <body class="node-1079336"> <a href="#main-content" class="visually-hidden focusable" data-elastic-exclude> Skip to main content </a> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <!-- nist-index-ignore-start --> <section data-elastic-exclude class="usa-banner" aria-label="Official government website"> <div class="usa-accordion"> <header class="usa-banner__header"> <div class="usa-banner__inner"> <div class="grid-col-auto"> <img class="usa-banner__header-flag" src="/libraries/nist-component-library/dist/img/us_flag_small.png" alt="U.S. flag"> </div> <div class="grid-col-fill tablet:grid-col-auto"> <p class="usa-banner__header-text">An official website of the United States government</p> <p class="usa-banner__header-action" aria-hidden="true">Here’s how you know</p> </div> <button class="usa-accordion__button usa-banner__button" aria-expanded="false" aria-controls="gov-banner-default"> <span class="usa-banner__button-text">Here’s how you know</span> </button> </div> </header> <div class="usa-banner__content usa-accordion__content" id="gov-banner-default"> <div class="grid-row grid-gap-lg"> <div class="usa-banner__guidance tablet:grid-col-6"> <img class="usa-banner__icon usa-media-block__img" src="/libraries/nist-component-library/dist/img/icon-dot-gov.svg" role="img" alt="" aria-hidden="true"> <div class="usa-media-block__body"> <p> <strong>Official websites use .gov</strong> <br/> A <strong>.gov</strong> website belongs to an official government organization in the United States. </p> </div> </div> <div class="usa-banner__guidance tablet:grid-col-6"> <img class="usa-banner__icon usa-media-block__img" src="/libraries/nist-component-library/dist/img/icon-https.svg" role="img" alt="" aria-hidden="true"> <div class="usa-media-block__body"> <p> <strong>Secure .gov websites use HTTPS</strong> <br/> A <strong>lock</strong> ( <span class="icon-lock"> <svg xmlns="http://www.w3.org/2000/svg" width="52" height="64" viewbox="0 0 52 64" class="usa-banner__lock-image" role="img" aria-labelledby="banner-lock-title banner-lock-description" focusable="false"> <title id="banner-lock-title">Lock</title> <desc id="banner-lock-description">A locked padlock</desc><path fill="#000000" fill-rule="evenodd" d="M26 0c10.493 0 19 8.507 19 19v9h3a4 4 0 0 1 4 4v28a4 4 0 0 1-4 4H4a4 4 0 0 1-4-4V32a4 4 0 0 1 4-4h3v-9C7 8.507 15.507 0 26 0zm0 8c-5.979 0-10.843 4.77-10.996 10.712L15 19v9h22v-9c0-6.075-4.925-11-11-11z"/></svg> </span> ) or <strong>https://</strong> means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites. </p> </div> </div> </div> </div> </div> </section> <!-- nist-index-ignore-end --> <div data-elastic-exclude> <!-- nist-index-ignore-start --> <div class="nist-print-header" style="display:none;"> <p class="nist-print-header__url">https://www.nist.gov/health</p> <img class="nist-print-header__logo" width="289" height="38" src="/libraries/nist-component-library/dist/img/logo/nist_logo_sidestack.svg" alt="National Institute of Standards and Technology" /> </div> <div class="usa-overlay"></div> <header class="usa-header nist-header--www nist-header--minimal" role="banner"> <div class="usa-navbar"> <div class="usa-logo flex-fill"> <a href="/" title="National Institute of Standards and Technology" aria-label="Home"> <img src="/libraries/nist-component-library/dist/img/logo/logo.svg" alt="National Institute of Standards and Technology" width="300px" height="80px" /> </a> </div> <div class="usa-header__right grid-row flex-auto"> <div class="grid-col-fill nist-header__search-group"> <form class="usa-search usa-search--small" accept-charset="UTF-8" action="/search" id="search_form" method="get"> <div role="search"> <label class="usa-sr-only" for="search-form">Search NIST</label> <input class="usa-input" id="search-form" type="search" name="s" placeholder="Search NIST" required="" maxlength="128"> <button class="usa-button" type="submit"><img src="/libraries/nist-component-library/dist/img/usa-icons-bg/search--white.svg" class="usa-search__submit-icon" alt="Search"></button> </div> </form> </div> <div class="grid-col-auto padding-left-1"> <button class="usa-menu-btn">Menu</button> </div> </div> </div> <nav aria-label="Primary navigation" class="usa-nav"> <div class="usa-nav__inner"> <button class="usa-nav__close">Close</button> <ul class="usa-nav__primary usa-accordion"> <li class="usa-nav__primary-item"> <button class="usa-accordion__button usa-nav__link usa-current" aria-expanded="false" aria-controls="primary_menu-1"><span>Topics</span></button> <div id="primary_menu-1" class="usa-nav__submenu usa-megamenu"> <div class="grid-row"> <div class="tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/topics" class="usa-nav__link">All Topics</a> </li> <li class="usa-nav__submenu-item"> <a href="/advanced-communications" class="usa-nav__link">Advanced communications</a> </li> <li class="usa-nav__submenu-item"> <a href="/artificial-intelligence" class="usa-nav__link">Artificial intelligence</a> </li> <li class="usa-nav__submenu-item"> <a href="/bioscience" class="usa-nav__link">Bioscience</a> </li> <li class="usa-nav__submenu-item"> <a href="/buildings-construction" class="usa-nav__link">Buildings and construction</a> </li> <li class="usa-nav__submenu-item"> <a href="/chemistry" class="usa-nav__link">Chemistry</a> </li> <li class="usa-nav__submenu-item"> <a href="/climate" class="usa-nav__link">Climate</a> </li> <li class="usa-nav__submenu-item"> <a href="/cybersecurity" class="usa-nav__link">Cybersecurity</a> </li> <li class="usa-nav__submenu-item"> <a href="/electronics" class="usa-nav__link">Electronics</a> </li> <li class="usa-nav__submenu-item"> <a href="/energy" class="usa-nav__link">Energy</a> </li> </ul></div><div class="column-break tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/environment" class="usa-nav__link">Environment</a> </li> <li class="usa-nav__submenu-item"> <a href="/fire" class="usa-nav__link">Fire</a> </li> <li class="usa-nav__submenu-item"> <a href="/forensic-science" class="usa-nav__link">Forensic science</a> </li> <li class="usa-nav__submenu-item"> <a href="/health" class="usa-nav__link usa-current">Health</a> </li> <li class="usa-nav__submenu-item"> <a href="/information-technology" class="usa-nav__link">Information technology</a> </li> <li class="usa-nav__submenu-item"> <a href="/infrastructure" class="usa-nav__link">Infrastructure</a> </li> <li class="usa-nav__submenu-item"> <a href="/manufacturing" class="usa-nav__link">Manufacturing</a> </li> <li class="usa-nav__submenu-item"> <a href="/materials" class="usa-nav__link">Materials</a> </li> <li class="usa-nav__submenu-item"> <a href="/mathematics-statistics" class="usa-nav__link">Mathematics and statistics</a> </li> </ul></div><div class="column-break tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/metrology" class="usa-nav__link">Metrology</a> </li> <li class="usa-nav__submenu-item"> <a href="/nanotechnology" class="usa-nav__link">Nanotechnology</a> </li> <li class="usa-nav__submenu-item"> <a href="/neutron-research" class="usa-nav__link">Neutron research</a> </li> <li class="usa-nav__submenu-item"> <a href="/performance-excellence" class="usa-nav__link">Performance excellence</a> </li> <li class="usa-nav__submenu-item"> <a href="/physics" class="usa-nav__link">Physics</a> </li> <li class="usa-nav__submenu-item"> <a href="/public-safety" class="usa-nav__link">Public safety</a> </li> <li class="usa-nav__submenu-item"> <a href="/quantum-information-science" class="usa-nav__link">Quantum information science</a> </li> <li class="usa-nav__submenu-item"> <a href="/resilience" class="usa-nav__link">Resilience</a> </li> <li class="usa-nav__submenu-item"> <a href="/standards" class="usa-nav__link">Standards</a> </li> <li class="usa-nav__submenu-item"> <a href="/transportation" class="usa-nav__link">Transportation</a> </li> </ul> </div> </div> </div> </li> <li class="usa-nav__primary-item"> <a class="usa-nav__link" href="/publications">Publications</a> </li> <li class="usa-nav__primary-item"> <button class="usa-accordion__button usa-nav__link" aria-expanded="false" aria-controls="primary_menu-3"><span>Labs & Major Programs</span></button> <div id="primary_menu-3" class="usa-nav__submenu usa-megamenu"> <div class="grid-row"> <div class="tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/adlp" class="usa-nav__link">Assoc Director of Laboratory Programs</a> </li> <li class="usa-nav__submenu-item"> <a href="/laboratories" class="usa-nav__link">Laboratories</a> <ul class="usa-nav__submenu-list"> <li> <a href="/ctl" class="usa-nav__link">Communications Technology Laboratory</a> </li> <li> <a href="/el" class="usa-nav__link">Engineering Laboratory</a> </li> <li> <a href="/itl" class="usa-nav__link">Information Technology Laboratory</a> </li> <li> <a href="/mml" class="usa-nav__link">Material Measurement Laboratory</a> </li> <li> <a href="/pml" class="usa-nav__link">Physical Measurement Laboratory</a> </li> </ul> </li> </ul></div><div class="column-break tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/user-facilities" class="usa-nav__link">User Facilities</a> <ul class="usa-nav__submenu-list"> <li> <a href="/ncnr" class="usa-nav__link">NIST Center for Neutron Research</a> </li> <li> <a href="/cnst" class="usa-nav__link">CNST NanoFab</a> </li> </ul> </li> <li class="usa-nav__submenu-item"> <a href="/labs-major-programs/research-test-beds" class="usa-nav__link">Research Test Beds</a> </li> <li class="usa-nav__submenu-item"> <a href="/laboratories/projects-programs" class="usa-nav__link">Research Projects</a> </li> <li class="usa-nav__submenu-item"> <a href="/laboratories/tools-instruments" class="usa-nav__link">Tools & Instruments</a> </li> </ul></div><div class="column-break tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/major-programs" class="usa-nav__link">Major Programs</a> <ul class="usa-nav__submenu-list"> <li> <a href="/baldrige" class="usa-nav__link">Baldrige Performance Excellence Program</a> </li> <li> <a href="/chips" class="usa-nav__link">CHIPS for America Initiative</a> </li> <li> <a href="/mep" class="usa-nav__link">Manufacturing Extension Partnership (MEP)</a> </li> <li> <a href="/oam" class="usa-nav__link">Office of Advanced Manufacturing</a> </li> <li> <a href="/spo" class="usa-nav__link">Special Programs Office</a> </li> <li> <a href="/tpo" class="usa-nav__link">Technology Partnerships Office</a> </li> </ul> </li> </ul> </div> </div> </div> </li> <li class="usa-nav__primary-item"> <button class="usa-accordion__button usa-nav__link" aria-expanded="false" aria-controls="primary_menu-4"><span>Services & Resources</span></button> <div id="primary_menu-4" class="usa-nav__submenu usa-megamenu"> <div class="grid-row"> <div class="tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/services-resources/standards-and-measurements" class="usa-nav__link">Standards and Measurements</a> <ul class="usa-nav__submenu-list"> <li> <a href="/calibrations" class="usa-nav__link">Calibration Services</a> </li> <li> <a href="/nvlap" class="usa-nav__link">Laboratory Accreditation (NVLAP)</a> </li> <li> <a href="/nist-quality-system" class="usa-nav__link">Quality System</a> </li> <li> <a href="/srm" class="usa-nav__link">Standard Reference Materials (SRMs)</a> </li> <li> <a href="/sri" class="usa-nav__link">Standard Reference Instruments (SRIs)</a> </li> <li> <a href="/standardsgov" class="usa-nav__link">Standards.gov</a> </li> <li> <a href="/pml/time-and-frequency-division/time-services" class="usa-nav__link">Time Services</a> </li> <li> <a href="/pml/owm" class="usa-nav__link">Office of Weights and Measures</a> </li> </ul> </li> </ul></div><div class="column-break tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/services-resources/software" class="usa-nav__link">Software</a> </li> <li class="usa-nav__submenu-item"> <a href="/data" class="usa-nav__link">Data</a> <ul class="usa-nav__submenu-list"> <li> <a href="https://webbook.nist.gov/chemistry/" class="usa-nav__link">Chemistry WebBook</a> </li> <li> <a href="https://nvd.nist.gov/" class="usa-nav__link">National Vulnerability Database</a> </li> <li> <a href="/pml/productsservices/physical-reference-data" class="usa-nav__link">Physical Reference Data</a> </li> <li> <a href="/srd" class="usa-nav__link">Standard Reference Data (SRD)</a> </li> </ul> </li> <li class="usa-nav__submenu-item"> <a href="https://www.nist.gov/shop" class="usa-nav__link">Storefront</a> </li> <li class="usa-nav__submenu-item"> <a href="/tpo" class="usa-nav__link">License & Patents</a> </li> </ul></div><div class="column-break tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="https://csrc.nist.gov/" class="usa-nav__link">Computer Security Resource Center (CSRC)</a> </li> <li class="usa-nav__submenu-item"> <a href="/nist-research-library" class="usa-nav__link">NIST Research Library</a> </li> </ul> </div> </div> </div> </li> <li class="usa-nav__primary-item"> <button class="usa-accordion__button usa-nav__link" aria-expanded="false" aria-controls="primary_menu-5"><span>News & Events</span></button> <div id="primary_menu-5" class="usa-nav__submenu usa-megamenu"> <div class="grid-row"> <div class="tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/news-events/news" class="usa-nav__link">News</a> </li> <li class="usa-nav__submenu-item"> <a href="/news-events/events" class="usa-nav__link">Events</a> </li> <li class="usa-nav__submenu-item"> <a href="/blogs" class="usa-nav__link">Blogs</a> </li> <li class="usa-nav__submenu-item"> <a href="/feature-stories" class="usa-nav__link">Feature Stories</a> </li> <li class="usa-nav__submenu-item"> <a href="/awards" class="usa-nav__link">Awards</a> </li> </ul></div><div class="column-break tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/video-gallery" class="usa-nav__link">Video Gallery</a> </li> <li class="usa-nav__submenu-item"> <a href="/image-gallery" class="usa-nav__link">Image Gallery</a> </li> <li class="usa-nav__submenu-item"> <a href="/pao/media-contacts" class="usa-nav__link">Media Contacts</a> </li> </ul> </div> </div> </div> </li> <li class="usa-nav__primary-item"> <button class="usa-accordion__button usa-nav__link" aria-expanded="false" aria-controls="primary_menu-6"><span>About NIST</span></button> <div id="primary_menu-6" class="usa-nav__submenu usa-megamenu"> <div class="grid-row"> <div class="tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/about-nist" class="usa-nav__link">About Us</a> <ul class="usa-nav__submenu-list"> <li> <a href="/director/leadership" class="usa-nav__link">Leadership</a> </li> <li> <a href="/director/nist-organization-structure" class="usa-nav__link">Organization Structure</a> </li> <li> <a href="/about-nist/budget-planning" class="usa-nav__link">Budget & Planning</a> </li> </ul> </li> <li class="usa-nav__submenu-item"> <a href="/about-nist/contact-us" class="usa-nav__link">Contact Us</a> </li> <li class="usa-nav__submenu-item"> <a href="/about-nist/visit" class="usa-nav__link">Visit</a> </li> <li class="usa-nav__submenu-item"> <a href="/careers" class="usa-nav__link">Careers</a> <ul class="usa-nav__submenu-list"> <li> <a href="/iaao/academic-affairs-office" class="usa-nav__link">Student programs</a> </li> </ul> </li> </ul></div><div class="column-break tablet:grid-col-fill"><ul class="usa-nav__submenu-list"> <li class="usa-nav__submenu-item"> <a href="/about-nist/work-nist" class="usa-nav__link">Work with NIST</a> </li> <li class="usa-nav__submenu-item"> <a href="/history" class="usa-nav__link">History</a> <ul class="usa-nav__submenu-list"> <li> <a href="http://nistdigitalarchives.contentdm.oclc.org/" class="usa-nav__link">NIST Digital Archives</a> </li> <li> <a href="/nist-museum" class="usa-nav__link">NIST Museum</a> </li> <li> <a href="/nist-and-nobel" class="usa-nav__link">NIST and the Nobel</a> </li> </ul> </li> <li class="usa-nav__submenu-item"> <a href="/education" class="usa-nav__link">Educational Resources</a> </li> </ul> </div> </div> </div> </li> </ul> </div> </nav> </header> <!-- nist-index-ignore-end --> </div> <div class="grid-container"> <div data-drupal-messages-fallback class="hidden"></div> </div> <div id="block-nist-www-content" class="nist-block" > <section class="nist-page__content usa-section clearfix" > <a id="main-content" tabindex="-1"></a> <div> <div class="nist-section-header nist-section-header--menu nist-section-header--topic nist-section-header--hero"> <div class="nist-section-header__hero-img"> <div class="nist-block nist-block--no-margin" > <div class="entity-reference"> <img loading="lazy" src="/sites/default/files/styles/topic_hero_1200_x_200/public/images/2021/03/08/Health_1200x248.jpg?itok=Hxb1L5kY" width="1200" height="200" alt="Black background. Up close bright blue orb" typeof="foaf:Image" /> </div> </div> </div> <div class="nist-section-header__main grid-container"> <div class="grid-row"> <div class="nist-section-header__title"> <h1 class="nist-page__title">Health</h1> </div> </div> </div> </div> </div> <section class="nist-page__content usa-section clearfix" > <a id="main-content" tabindex="-1"></a> <div class="grid-container margin-top-4"> <div class="grid-row grid-gap-6"> <aside class="nist-page__region nist-page__region--sidebar-first tablet-lg:grid-col-4 desktop-lg:grid-col-3"> <div> <!-- nist-index-ignore-start --> <div data-elastic-exclude="" class="nist-block" > <nav> <ul class="usa-sidenav usa-accordion "> <li class="usa-sidenav__item"> <a href="/feature-stories/finding-forever-chemicals-wherever-theyre-hiding" data-drupal-link-system-path="">Finding PFAS Wherever They’re Hiding</a> </li> <li class="usa-sidenav__item"> <a href="/health/future-medicine-your-poop" data-drupal-link-system-path="">Turning Fecal Matter into Medicine</a> </li> <li class="usa-sidenav__item"> <a href="/physics/what-are-imaging-phantoms" data-drupal-link-system-path="">What Are Imaging Phantoms?</a> </li> <li class="usa-sidenav__item usa-sidenav__item--parent"> <a href="/how-do-you-measure-it" data-drupal-link-system-path="">How Do You Measure It?</a> <button class="usa-accordion__button" aria-expanded="false" aria-controls="health-topic-area-4"><span class="usa-sr-only">Expand or Collapse</span></button> <ul id="health-topic-area-4" class="usa-sidenav__sublist usa-accordion"> <li class="usa-sidenav__item"> <a href="/how-do-you-measure-it/how-do-you-know-your-foods-nutrition-facts-label-accurate" data-drupal-link-system-path="">How Do You Know Your Food’s Nutrition Facts Label Is Accurate?</a> </li> <li class="usa-sidenav__item"> <a href="/how-do-you-measure-it/how-do-you-measure-cholesterol-blood-tests" data-drupal-link-system-path="">How Do You Measure Cholesterol in Blood Tests?</a> </li> </ul> </li> </ul> </nav> </div> <!-- nist-index-ignore-end --> <div class="nist-block nist-social__wrapper--block" > <h2 class="nist-block__title" >Sign Up to Get NIST News</h2> <div><a href="https://public.govdelivery.com/accounts/USNIST/subscriber/new?topic_id=USNIST_5" class="nist-social nist-social--envelope" title="GovDelivery" ><span>GovDelivery</span></a></div> </div> <!-- nist-index-ignore-start --> <div class="views-element-container nist-block nist-block--topic" data-elastic-exclude="" > <div><div class="js-view-dom-id-6b012f49fe560c88cdcdc38f47fe0768fb8acbce826ea1f607419849c08a8209"> <div class="link-list"> <h2 class="nist-block__title">Health Topics</h2> <ul> <li><div class="views-field views-field-field-shared-section"><div class="field-content"><a href="/pharmaceuticals" hreflang="en">Pharmaceuticals</a></div></div></li> <li><div class="views-field views-field-field-shared-section"><div class="field-content"><a href="/cell-and-gene-therapy" hreflang="en">Cell and gene therapy</a></div></div></li> <li><div class="views-field views-field-field-shared-section"><div class="field-content"><a href="/clinical-diagnostics" hreflang="en">Clinical diagnostics</a></div></div></li> <li><div class="views-field views-field-field-shared-section"><div class="field-content"><a href="/dentistry" hreflang="en">Dentistry</a></div></div></li> <li><div class="views-field views-field-field-shared-section"><div class="field-content"><a href="/food-nutrition" hreflang="en">Food & nutrition</a></div></div></li> <li><div class="views-field views-field-field-shared-section"><div class="field-content"><a href="/human-microbiome" hreflang="en">Human microbiome</a></div></div></li> <li><div class="views-field views-field-field-shared-section"><div class="field-content"><a href="/medical-imaging" hreflang="en">Medical imaging</a></div></div></li> <li><div class="views-field views-field-field-shared-section"><div class="field-content"><a href="/precision-medicine" hreflang="en">Precision medicine</a></div></div></li> <li><div class="views-field views-field-field-shared-section"><div class="field-content"><a href="/regenerative-medicine" hreflang="en">Regenerative medicine</a></div></div></li> </ul> </div> </div> </div> </div> <!-- nist-index-ignore-end --> </div> </aside> <div class="nist-page__region nist-page__region--content tablet-lg:grid-col-8 desktop-lg:grid-col-9" > <div class="text-with-summary margin-bottom-5"> <p>NIST provides measurement assurance for biomedical stakeholders through the development of measurement tools for medical devices, clinical diagnostics, imaging tools and the characterization of complex biotherapeutics.</p> </div> <div class="nist-block" > <div class="nist-content-row nist-content-row--width-legible paragraph paragraph--type--text paragraph--view-mode--default"> <div class="nist-block text-long"><h2 class="nist-block__title">Key Accomplishments</h2><ul><li><strong>Face coverings:</strong> In an effort to improve the fabric masks that people wear to slow the spread of COVID-19, <a href="/feature-stories/masks-under-microscope" data-entity-type="node" data-entity-uuid="40e44538-1db5-48c1-9ba3-ba3817c1d6f6" data-entity-substitution="canonical" title="Masks Under the Microscope">NIST scientists have measured</a> how well various fabrics filter out aerosols that might contain the virus. This research contributed to standards for fabric face masks that will give people information on how well their masks work.</li><li><strong>Biopharmaceuticals: </strong>The <a href="/news-events/news/2016/07/extraordinary-standard-new-nist-protein-could-spur-biopharmaceutical" data-entity-type="node" data-entity-uuid="f208228f-a2bc-4692-8b6e-183b133ceac3" data-entity-substitution="canonical" title="An Extraordinary Standard: New NIST Protein Could Spur Biopharmaceutical Innovation">NIST Monoclonal Antibody reference material</a> is an intensively analyzed protein of over 20,000 atoms that researchers and manufacturers use when developing vaccines and treatments for cancer and other diseases. Also called the NISTmAb, this material promotes innovation in the biopharmaceutical industry and helps ensure the quality and safety of our drug supply.</li><li><strong>Nutrition labeling:</strong> To help ensure the accuracy of nutrition labels, NIST manufactures over 30 <a href="/programs-projects/measurements-and-standards-support-nutrition-labeling" data-entity-type="node" data-entity-uuid="7663e40c-c210-4ff8-8b7f-15c506924517" data-entity-substitution="canonical" title="Measurements and Standards to Support Nutrition Labeling">food-based reference materials</a>, including infant formula, baking chocolate, spinach and food oils. Labs use these reference materials to calibrate their instruments for measuring the carbohydrates, proteins, calories and other values listed on nutrition labels.</li><li><strong>MRI calibration:</strong> The <a href="/physics/what-are-imaging-phantoms" data-entity-type="node" data-entity-uuid="fa7fd4b5-1a08-4d69-9f10-ce8ea6d7874f" data-entity-substitution="canonical" title="What Are Imaging Phantoms?">NIST phantom</a> helps ensure that magnetic resonance imaging (MRI) machines produce accurate results. Also called the “phannie,” this plastic sphere is about the size of a person’s head and contains contrast-enhancing agents and other materials that aid in calibrating MRI instruments.</li></ul></div> </div> <div class="margin-y-4"> <h2 class="nist-block__title"> <div class="string">Feature Stories and Explainers</div> </h2> <div class="grid-row grid-gap-2"> <div class="nist-card tablet:grid-col-4 "> <div class="nist-card__inner"> <div class="nist-card__image"> <a href="/feature-stories/finding-forever-chemicals-wherever-theyre-hiding"> <div class="entity-reference"> <a href="/feature-stories/finding-forever-chemicals-wherever-theyre-hiding" hreflang="en"><img loading="lazy" src="/sites/default/files/styles/400_x_250_focal_point/public/images/2024/02/29/DSC_3874.jpg?itok=oMRWvZ69" width="400" height="250" alt="Alix Rodowa wears safety glasses and gloves in the lab as she reaches for a container of clear liquid on top of a piece of scientific equipment. " typeof="foaf:Image" /> </a> </div> </a> </div> <div class="nist-card__title padding-y-5"> <h3><span>Finding PFAS Wherever They’re Hiding</span> </h3> </div> <div class="nist-card__links"> <div class="nist-card__button"> <a href="/feature-stories/finding-forever-chemicals-wherever-theyre-hiding" class="usa-button ">Read more</a> </div> </div> </div> </div> <div class="nist-card tablet:grid-col-4 "> <div class="nist-card__inner"> <div class="nist-card__image"> <a href="/health/future-medicine-your-poop"> <div class="entity-reference"> <a href="/health/future-medicine-your-poop" hreflang="en"><img loading="lazy" src="/sites/default/files/styles/400_x_250_focal_point/public/images/2024/04/18/shutterstock_1184076262_VectorMine.png?itok=fFc0IzsK" width="400" height="250" alt="Illustration shows blender with brown material alongside vials of brown liquid and pills, and a petri dish holding poop. " typeof="foaf:Image" /> </a> </div> </a> </div> <div class="nist-card__title padding-y-5"> <h3><span property="schema:name">The Future of Medicine Is in Your Poop</span> </h3> </div> <div class="nist-card__links"> <div class="nist-card__button"> <a href="/health/future-medicine-your-poop" class="usa-button ">Read more</a> </div> </div> </div> </div> <div class="nist-card tablet:grid-col-4 "> <div class="nist-card__inner"> <div class="nist-card__image"> <a href="/physics/what-are-imaging-phantoms"> <div class="entity-reference"> <a href="/physics/what-are-imaging-phantoms" hreflang="en"><img loading="lazy" src="/sites/default/files/styles/400_x_250_focal_point/public/images/ctl/rf-technology/10eeel009_phannie_lr.jpg?itok=fLjveIOF" width="400" height="250" alt="phannie" typeof="foaf:Image" /> </a> </div> </a> </div> <div class="nist-card__title padding-y-5"> <h3><span property="schema:name">What Are Imaging Phantoms?</span> </h3> </div> <div class="nist-card__links"> <div class="nist-card__button"> <a href="/physics/what-are-imaging-phantoms" class="usa-button ">Read more</a> </div> </div> </div> </div> </div> </div> <div class="margin-y-8"> <a href="/publications/search?ta%5B0%5D=248651" class="nist-topic-big-button" role="button" aria-label="Check out NIST publications about health"> View health publications <span class="nist-icon nist-icon--before nist-icon--chevron-right-blue" aria-hidden="true"></span> </a> </div> <div class="margin-y-4"> <h2 class="nist-block__title">News</h2> <div class="margin-bottom-5"> <div class="entity-reference"> <div class="nist-card nist-card--horizontal nist-card--horizontal-full"> <div class="nist-card__inner"> <div class="nist-card__image"> <a href="/blogs/taking-measure/how-measurement-science-can-help-protect-us-viruses"> <div class="entity-reference"> <img loading="lazy" src="/sites/default/files/styles/600w_x_360h/public/images/2023/10/26/jerilyn_izac_measuring_sample_in_lab_101623.jpg.webp?itok=DwHXVTyP" width="600" height="360" alt="Jerilyn Izac sits at a lab bench with her hands inside a plastic shield, using a device to draw liquid from a plastic container into a tube. " typeof="foaf:Image" /> </div> </a> </div> <div class="nist-card__title"> <h3><span>How Measurement Science Can Help Protect Us From Viruses</span> </h3> </div> <div class="nist-card__content"> <div class="text-with-summary"> Imagine if for the next dangerous virus, we could quickly and easily test everyone’s levels of defenses — known as antibodies. </div> </div> <div class="nist-card__links"> <div class="nist-card__button"> <a href="/blogs/taking-measure/how-measurement-science-can-help-protect-us-viruses" class="usa-button ">Read more</a> </div> </div> </div> </div> </div> </div> <div class="paragraph paragraph--type--dynamic-news-list-topic paragraph--view-mode--default"> <div class="views-element-container"><div class="js-view-dom-id-9f8557c8be41dbc8c38a018750f44a305b3275817b6e0264ffd0806d7689a119"> <div class="grid-row grid-gap-2"> <div class="nist-card tablet:grid-col-4 nist-card--topic "> <div class="nist-card__inner"> <div class="nist-card__image"> <a href="/news-events/news/2024/10/nist-scientists-use-dna-origami-chip-detect-biomolecules"> <div class="entity-reference"> <img loading="lazy" src="/sites/default/files/styles/400_x_250_focal_point/public/images/2024/10/17/thumb%20%283%29.png?h=1e66e246&itok=RsKrr6BX" width="400" height="250" alt="DNA hinge thumbnail" typeof="foaf:Image" /> </div> </a> </div> <div class="nist-card__title padding-y-5"> <h3><span property="schema:name">NIST Scientists Use DNA Origami on a Chip to Detect Biomolecules</span> </h3> </div> <div class="nist-card__links"> <div class="nist-card__button"> <a href="/news-events/news/2024/10/nist-scientists-use-dna-origami-chip-detect-biomolecules" class="usa-button ">Read more</a> </div> </div> </div> </div> <div class="nist-card tablet:grid-col-4 nist-card--topic "> <div class="nist-card__inner"> <div class="nist-card__image"> <a href="/news-events/news/2024/10/nist-awards-15-million-support-development-regenerative-medicine-standards"> <div class="entity-reference"> <img loading="lazy" src="/sites/default/files/styles/400_x_250_focal_point/public/images/2024/10/07/shutterstock_1924512557.jpg?h=4462e40b&itok=pd8sbhJc" width="400" height="250" alt="A male researcher in a high-tech medical lab holds up a vial of blue liquid while a female researcher next to him leans in to look at it." typeof="foaf:Image" /> </div> </a> </div> <div class="nist-card__title padding-y-5"> <h3><span property="schema:name">NIST Awards Up to $1.5 Million to Support Development of Regenerative Medicine Standards Curricula</span> </h3> </div> <div class="nist-card__links"> <div class="nist-card__button"> <a href="/news-events/news/2024/10/nist-awards-15-million-support-development-regenerative-medicine-standards" class="usa-button ">Read more</a> </div> </div> </div> </div> <div class="nist-card tablet:grid-col-4 nist-card--topic "> <div class="nist-card__inner"> <div class="nist-card__image"> <a href="/news-events/news/2024/08/spotlight-cassie-stoffer-helps-run-calibration-and-measurement-services"> <div class="entity-reference"> <img loading="lazy" src="/sites/default/files/styles/400_x_250_focal_point/public/images/2024/09/03/StofferNMR%20%281%29.jpg?itok=uRgughgJ" width="400" height="250" alt="Cassie Stoffer smiles while wearing safety glasses and standing next to a large metal tank with many pipes and wires attached to it. " typeof="foaf:Image" /> </div> </a> </div> <div class="nist-card__title padding-y-5"> <h3><span property="schema:name">Spotlight: Cassie Stoffer Helps Run Calibration and Measurement Services Related to Magnetic Resonance</span> </h3> </div> <div class="nist-card__links"> <div class="nist-card__button"> <a href="/news-events/news/2024/08/spotlight-cassie-stoffer-helps-run-calibration-and-measurement-services" class="usa-button ">Read more</a> </div> </div> </div> </div> </div> <footer> <div class="link-list"><a href="/news-events/news-updates/topic/248651">View All News and Updates</a></div> </footer> </div> </div> </div> </div> <div class="margin-y-8"> <a href="/news-events/events/search?k=&topic-op=or&topic-area-fieldset%5B%5D=248651" class="nist-topic-big-button" role="button" aria-label="Check out NIST events about health"> View health events <span class="nist-icon nist-icon--before nist-icon--chevron-right-blue" aria-hidden="true"></span> </a> </div> </div> </div> </div> </div> <div class="grid-container"> </div> </section> </section> </div> <div data-elastic-exclude> <!-- nist-index-ignore-start --> <footer class="nist-footer padding-bottom-4"> <div class="grid-container nist-footer__info"> <div class="grid-row"> <div class="tablet:grid-col-6"> <div class="nist-footer__logo"> <a href="/" title="National Institute of Standards and Technology" rel="home"> <img class="nist-footer__logo-img" src="/libraries/nist-component-library/dist/img/logo/NIST-Logo-Brand-White.svg" alt="National Institute of Standards and Technology logo" width="300px" height="42px" /> </a> </div> <div class="nist-footer__contact"> <h3 class="nist-footer__contact-heading">HEADQUARTERS</h3> <address> 100 Bureau Drive<br> Gaithersburg, MD 20899<br> <a href="tel:301-975-2000">301-975-2000</a> </address> <p> <a href="mailto:do-webmaster@nist.gov">Webmaster</a> | <a href="https://www.nist.gov/about-nist/contact-us">Contact Us</a> | <a href="https://www.nist.gov/visit">Our Other Offices</a> </p> </div> </div> <div class="tablet:grid-col-6"> <div class="nist-footer__social-links"> <a class="nist-social nist-social--x-white" href=" https://x.com/NIST"> <span>X.com</span> </a> <a class="nist-social nist-social--facebook-white" href=" https://www.facebook.com/NIST"> <span>Facebook</span> </a> <a class="nist-social nist-social--linkedin-white" href=" https://www.linkedin.com/company/nist"> <span>LinkedIn</span> </a> <a class="nist-social nist-social--instagram-white" href=" https://www.instagram.com/nist/"> <span>Instagram</span> </a> <a class="nist-social nist-social--youtube-white" href=" https://www.youtube.com/NIST"> <span>YouTube</span> </a> <a class="nist-social nist-social--giphy-white" href=" https://giphy.com/nist"> <span>Giphy</span> </a> <a class="nist-social nist-social--rss-white" href=" https://www.nist.gov/news-events/nist-rss-feeds"> <span>RSS Feed</span> </a> <a class="nist-social nist-social--envelope-white" href=" https://public.govdelivery.com/accounts/USNIST/subscriber/new"> <span>Mailing List</span> </a> </div> <div class="nist-footer__feedback"> How are we doing? <a class="usa-button" rel="nofollow" href="/form/nist-gov-feedback?destination=/health" title="Provide feedback">Feedback</a> </div> </div> </div> </div> <div class="grid-container"> <div class="nist-footer__nav" role="navigation"> <ul> <li class="nist-footer__menu-item"> <a href="https://www.nist.gov/privacy-policy">Site Privacy</a> </li> <li class="nist-footer__menu-item"> <a href="https://www.nist.gov/oism/accessibility">Accessibility</a> </li> <li class="nist-footer__menu-item"> <a href="https://www.nist.gov/privacy">Privacy Program</a> </li> <li class="nist-footer__menu-item"> <a href="https://www.nist.gov/oism/copyrights">Copyrights</a> </li> <li class="nist-footer__menu-item"> <a href="https://www.commerce.gov/vulnerability-disclosure-policy">Vulnerability Disclosure</a> </li> <li class="nist-footer__menu-item"> <a href="https://www.nist.gov/no-fear-act-policy">No Fear Act Policy</a> </li> <li class="nist-footer__menu-item"> <a href="https://www.nist.gov/office-director/freedom-information-act">FOIA</a> </li> <li class="nist-footer__menu-item"> <a href="https://www.nist.gov/environmental-policy-statement">Environmental Policy</a> </li> <li class="nist-footer__menu-item"> <a href="https://www.nist.gov/summary-report-scientific-integrity">Scientific Integrity</a> </li> <li class="nist-footer__menu-item"> <a href="https://www.nist.gov/nist-information-quality-standards">Information Quality Standards</a> </li> <li class="nist-footer__menu-item"> <a href="https://www.commerce.gov/">Commerce.gov</a> </li> <li class="nist-footer__menu-item"> <a href="http://www.science.gov/">Science.gov</a> </li> <li class="nist-footer__menu-item"> <a href="http://www.usa.gov/">USA.gov</a> </li> <li class="nist-footer__menu-item"> <a href="https://vote.gov/">Vote.gov</a> </li> </ul> </div> </div> </footer> <!-- nist-index-ignore-end --> </div> </div> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"","currentPath":"node\/1079336","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"back_to_top":{"back_to_top_button_trigger":100,"back_to_top_speed":1200,"back_to_top_prevent_on_mobile":false,"back_to_top_prevent_in_admin":true,"back_to_top_button_type":"image","back_to_top_button_text":"Back to top"},"google_analytics":{"account":"G-HEQ0YF2VYL","trackOutbound":true,"trackMailto":true,"trackTel":true,"trackDownload":true,"trackDownloadExtensions":"7z|aac|arc|arj|asf|asx|avi|bin|bsh|c|csv|doc(x|m)?|dot(x|m)?|dw(fx|g|gd)|dxf|eps|epub|exe|f(90)|flv|gif|gz|gzip|hqx|jar|jpe?g|js|m1v|mp(2|3|4|e?g)|mobi|mov(ie)?|msi|msp|pdf|phps|pl|png|ppt(x|m)?|pot(x|m)?|pps(x|m)?|ppam|sld(x|m)?|thmx|qtm?|ra(m|r)?|rfa|rtf|rvt|sch|sea|sit|swf|tar|tgz|tif|txt|txz|wav|wma|wmv|wpd|wrl|xls(x|m|b)?|xlt(x|m)|xlam|xml|xsd|z|zip"},"nist_search":{"clickTracking":"search-report-click","isDebug":false,"clickTrackEnabled":true,"message":"NIST Search in debug mode. Check the browsers network inspector for Click Track reporting results..."},"data":{"extlink":{"extTarget":false,"extTargetNoOverride":false,"extNofollow":false,"extNoreferrer":false,"extFollowNoOverride":false,"extClass":"ext","extLabel":"(link is external)","extImgClass":false,"extSubdomains":true,"extExclude":"\\.gov\\\/|\\.mil\\\/|\\manufacturingusa\\.com\\\/","extInclude":"","extCssExclude":".ck-editor, .nist-social, .nist-video-thumbnail__lightbox-trigger, a.nist-icon--mail-blue","extCssExplicit":"","extAlert":true,"extAlertText":"Thank you for visiting NIST. We hope your visit was informative. We have provided a link to this site because it has information that may be of interest to our users. NIST does not necessarily endorse the views expressed or the facts presented on this site. Further, NIST does not endorse any commercial products that may be advertised or available on this site. Click OK to be directed to your link.","mailtoClass":"0","mailtoLabel":"(link sends email)","extUseFontAwesome":false,"extIconPlacement":"after","extFaLinkClasses":"fa fa-external-link","extFaMailtoClasses":"fa fa-envelope-o","whitelistedDomains":[]}},"user":{"uid":0,"permissionsHash":"799e86e1b846dec23e8558802ab352c65189779447aba2515e9cc22afa524258"}}</script> <script src="/sites/default/files/js/js_PHU9IaMjouCKyPeRMxGVOgc3bD_uuzlYV49YBhns0xg.js?scope=footer&delta=0&language=en&theme=nist_www&include=eJx1TwGOwyAM-xBXnoRCySC3lDAC6-33R3udWk06CaHYjmzHw3x3TcYr1p-z-1bj_5FolmyiSGR0kIFfjWa1n4TJpM3daHBB1swCwbU6bChHG-FPVmpIS6nyRPtJbBV2riVccCQLe6hukWADKfhhzJTvRl_acBkNFfd9G1k88HX-OqxsQghY39Ct63rdvuBtBX_aFmBD7QV4OqApUCFWKEnfyslMPZfumTRhME_CVe3-T6N156MfPjqwS0gxtTN3obnKdv4vXRCeuQ"></script> <script src="https://siteimproveanalytics.com/js/siteanalyze_6017546.js" async></script> <script src="/sites/default/files/js/js_WnMCIHWCdin8GNNpQ3oTaVkN58d1iRwcWUPqlGouIM4.js?scope=footer&delta=2&language=en&theme=nist_www&include=eJx1TwGOwyAM-xBXnoRCySC3lDAC6-33R3udWk06CaHYjmzHw3x3TcYr1p-z-1bj_5FolmyiSGR0kIFfjWa1n4TJpM3daHBB1swCwbU6bChHG-FPVmpIS6nyRPtJbBV2riVccCQLe6hukWADKfhhzJTvRl_acBkNFfd9G1k88HX-OqxsQghY39Ct63rdvuBtBX_aFmBD7QV4OqApUCFWKEnfyslMPZfumTRhME_CVe3-T6N156MfPjqwS0gxtTN3obnKdv4vXRCeuQ"></script> <script type="text/javascript">window.NREUM||(NREUM={});NREUM.info={"beacon":"bam.nr-data.net","licenseKey":"37b7ccb661","applicationID":"1089704227","transactionName":"YFxUN0sADEdYVkBaClkWdwBNCA1aFkVVVABoWlcAUQQ=","queueTime":3,"applicationTime":35,"atts":"TBtXQQMaH0k=","errorBeacon":"bam.nr-data.net","agent":""}</script></body> </html>