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window.loswp.work = {"work":{"id":14224558,"created_at":"2015-07-20T13:02:28.492-07:00","from_world_paper_id":139862316,"updated_at":"2025-01-31T16:02:50.416-08:00","_data":{"ai_abstract":"Tissue engineering offers potential advancements in regenerative medicine, particularly in the field of urology. The interdisciplinary approach combines engineering, biology, and medicine to develop biological substitutes that can improve therapeutic outcomes for patients. Various methods, including cell-based therapies and biomaterials, are being explored, yet challenges related to implementation, such as regulatory compliance and ethical considerations, continue to hinder progress.","ai_title_tag":"Tissue Engineering in Regenerative Medicine","publication_date":"2011,,","publication_name":"Advanced Drug Delivery Reviews"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"From tissue engineering to regenerative medicine—the potential and the pitfalls","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [33204303]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loginModal = {}; window.loginModal.appleClientId = 'edu.academia.applesignon'; window.userInChina = "false";</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{"location":"swp-splash-paper-cover","attachmentId":44440811,"attachmentType":"pdf"}"><img alt="First page of “From tissue engineering to regenerative medicine—the potential and the pitfalls”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/44440811/mini_magick20190214-438-1ritosa.png?1550181565" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/images/single_work_splash/adobe_icon.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">From tissue engineering to regenerative medicine—the potential and the pitfalls</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="33204303" href="https://uni-tuebingen.academia.edu/KatjaSchenkelayland"><img alt="Profile image of Katja Schenke-layland" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Katja Schenke-layland</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2011, Advanced Drug Delivery Reviews</p><div class="ds-work-card--work-metadata"><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">visibility</span><p class="ds2-5-body-sm" id="work-metadata-view-count">…</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">description</span><p class="ds2-5-body-sm">4 pages</p></div><div class="ds-work-card--work-metadata__stat"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">link</span><p class="ds2-5-body-sm">1 file</p></div></div><script>(async () => { const workId = 14224558; const worksViewsPath = "/v0/works/views?subdomain_param=api&work_ids%5B%5D=14224558"; const getWorkViews = async (workId) => { const response = await fetch(worksViewsPath); if (!response.ok) { throw new Error('Failed to load work views'); } const data = await response.json(); return data.views[workId]; }; // Get the view count for the work - we send this immediately rather than waiting for // the DOM to load, so it can be available as soon as possible (but without holding up // the backend or other resource requests, because it's a bit expensive and not critical). const viewCount = await getWorkViews(workId); const updateViewCount = (viewCount) => { try { const viewCountNumber = parseInt(viewCount, 10); if (viewCountNumber === 0) { // Remove the whole views element if there are zero views. document.getElementById('work-metadata-view-count')?.parentNode?.remove(); return; } const commaizedViewCount = viewCountNumber.toLocaleString(); const viewCountBody = document.getElementById('work-metadata-view-count'); if (!viewCountBody) { throw new Error('Failed to find work views element'); } viewCountBody.textContent = `${commaizedViewCount} views`; } catch (error) { // Remove the whole views element if there was some issue parsing. document.getElementById('work-metadata-view-count')?.parentNode?.remove(); throw new Error(`Failed to parse view count: ${viewCount}`, error); } }; // If the DOM is still loading, wait for it to be ready before updating the view count. if (document.readyState === "loading") { document.addEventListener('DOMContentLoaded', () => { updateViewCount(viewCount); }); // Otherwise, just update it immediately. } else { updateViewCount(viewCount); } })();</script></div><p class="ds-work-card--detail ds2-5-body-md">AI-generated Abstract</p><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">Tissue engineering offers potential advancements in regenerative medicine, particularly in the field of urology. The interdisciplinary approach combines engineering, biology, and medicine to develop biological substitutes that can improve therapeutic outcomes for patients. Various methods, including cell-based therapies and biomaterials, are being explored, yet challenges related to implementation, such as regulatory compliance and ethical considerations, continue to hinder progress.</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":44440811,"attachmentType":"pdf","workUrl":"https://www.academia.edu/14224558/From_tissue_engineering_to_regenerative_medicine_the_potential_and_the_pitfalls"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":44440811,"attachmentType":"pdf","workUrl":"https://www.academia.edu/14224558/From_tissue_engineering_to_regenerative_medicine_the_potential_and_the_pitfalls"}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div><div class="ds-signup-banner-trigger-container"><div class="ds-signup-banner-trigger ds-signup-banner-trigger-control"></div></div><div class="ds-signup-banner ds-signup-banner-control"><div id="ds-signup-banner-close-button"><button class="ds2-5-button ds2-5-button--secondary ds2-5-button--inverse"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">close</span></button></div><div class="ds-signup-banner-ctas"><img src="//a.academia-assets.com/images/academia-logo-capital-white.svg" /><h4 class="ds2-5-heading-serif-sm">Sign up for access to the world's latest research</h4><button class="ds2-5-button ds2-5-button--inverse ds2-5-button--full-width js-swp-download-button" data-signup-modal="{"location":"signup-banner"}">Sign up for free<span class="material-symbols-outlined" style="font-size: 20px" translate="no">arrow_forward</span></button></div><div class="ds-signup-banner-divider"></div><div class="ds-signup-banner-reasons"><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Get notified about relevant papers</span></div><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Save papers to use in your research</span></div><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Join the discussion with peers</span></div><div class="ds-signup-banner-reasons-item"><span class="material-symbols-outlined" style="font-size: 24px" translate="no">check</span><span>Track your impact</span></div></div></div><script>(() => { // Set up signup banner show/hide behavior: // 1. 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This field of science has many things to offer in reconstructive urology where native organ is non-functional, and no substitute is available. Despite the initial promising results, it has not become a reality in the true sense. There are numerous obstacles that are slowing down the process of regenerative medicine. The progress shown in stem cell biotechnology and material science provides new vistas to translate experimental methods clinical reality. Tissue engineering encompasses a multidisciplinary approach with the main aim of development of biological substitutes designed to restore and maintain normal function in diseased or injured organs. This review is done to ascertain its current status and the progress that has been made in regenerative medicine in the reconstruction of various Genito-urinary organs.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Tissue Engineering in Urology- Progress and Prospects - A Review Article","attachmentId":68240251,"attachmentType":"pdf","work_url":"https://www.academia.edu/50143101/Tissue_Engineering_in_Urology_Progress_and_Prospects_A_Review_Article","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/50143101/Tissue_Engineering_in_Urology_Progress_and_Prospects_A_Review_Article"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="117052365" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/117052365/State_of_the_Art_of_Clinical_Applications_of_Tissue_Engineering_in_2021">State of the Art of Clinical Applications of Tissue Engineering in 2021</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58181796" href="https://independent.academia.edu/JanVranckx">Jan Vranckx</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Tissue Engineering Part B: Reviews, 2021</p><p class="ds-related-work--abstract ds2-5-body-sm">Tissue engineering (TE) was introduced almost 30 years ago as a potential technique for regenerating human tissues. However, despite promising laboratory findings, the complexity of the human body, scientific hurdles, and lack of persistent long-term funding still hamper its translation toward clinical applications. In this report, we compile an inventory of clinically applied TE medical products relevant to surgery. A review of the literature, including articles published within the period from 1991 to 2020, was performed according to the PRISMA protocol, using databanks PubMed, Cochrane Library, Web of Science, and Clinicaltrials.gov. We identified 1039 full-length articles as eligible; owing to the scarcity of clinical, randomized, controlled trials and case studies, we extended our search toward a broad surgical spectrum. Forty articles involved clinical TE studies. Among these, seven were related to TE protocols for cartilage applied in the reconstruction of nose, ear, and trachea. Nine articles reported TE protocols for articular cartilage, nine for urological purposes, seven described TE strategies for cardiovascular aims, and eight for dermal applications. However, only two clinical studies reported on three-dimensional (3D) and functional long-lasting TE constructs. The concept of generating 3D TE constructs and organs based on autologous molecules and cells is intriguing and promising. The first translational tissue-engineered products and techniques have been clinically implemented. However, despite the 30 years of research and development in this field, TE is still in its clinical infancy. Multiple experimental, ethical, budgetary, and regulatory difficulties hinder its rapid translation. Nevertheless, the first clinical applications show great promise and indicate that the translation toward clinical medical implementation has finally started.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"State of the Art of Clinical Applications of Tissue Engineering in 2021","attachmentId":113014334,"attachmentType":"pdf","work_url":"https://www.academia.edu/117052365/State_of_the_Art_of_Clinical_Applications_of_Tissue_Engineering_in_2021","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/117052365/State_of_the_Art_of_Clinical_Applications_of_Tissue_Engineering_in_2021"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="125143301" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/125143301/Regenerative_Medicine_and_Tissue_Engineering_Advancements_and_Challenges_in_Cell_Based_Therapies">Regenerative Medicine and Tissue Engineering: Advancements and Challenges in Cell-Based Therapies</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="139181401" href="https://independent.academia.edu/El%C3%A7inT%C3%B6ren">Elçin Tören</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2023</p><p class="ds-related-work--abstract ds2-5-body-sm">Regenerative Medicine and Tissue Engineering are interdisciplinary fields that combine cell biology, material science, and bioengineering to develop therapies for tissue repair and regeneration. This field has made significant advances in recent years, particularly in the use of stem cells and biomaterials. Advancements in cell-based therapies have involved the use of cells to repair or replace damaged tissues and organs. Tissue engineering involves using scaffolds and growth factors to promote tissue regeneration. However, a major challenge in this field is the formation of adhesions, which can cause complications, such as intestinal obstruction and chronic pain. Adhesion barriers are used to prevent adhesion of tissues and organs during recovery, thereby reducing the risk of complications. Anti-adhesion materials, such as polysaccharides, proteins, and synthetic polymers, are used to create a physical barrier between tissues and prevent adhesion. These materials can be used alone or in combination, but their effectiveness varies.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Regenerative Medicine and Tissue Engineering: Advancements and Challenges in Cell-Based Therapies","attachmentId":119238455,"attachmentType":"pdf","work_url":"https://www.academia.edu/125143301/Regenerative_Medicine_and_Tissue_Engineering_Advancements_and_Challenges_in_Cell_Based_Therapies","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/125143301/Regenerative_Medicine_and_Tissue_Engineering_Advancements_and_Challenges_in_Cell_Based_Therapies"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="68583690" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/68583690/Advances_in_Regenerative_Medicine_and_Tissue_Engineering_Innovation_and_Transformation_of_Medicine">Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="38366464" href="https://uct.academia.edu/KevinDzobo">Kevin Dzobo</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Stem cells international, 2018</p><p class="ds-related-work--abstract ds2-5-body-sm">Humans and animals lose tissues and organs due to congenital defects, trauma, and diseases. The human body has a low regenerative potential as opposed to the urodele amphibians commonly referred to as salamanders. Globally, millions of people would benefit immensely if tissues and organs can be replaced on demand. Traditionally, transplantation of intact tissues and organs has been the bedrock to replace damaged and diseased parts of the body. The sole reliance on transplantation has created a waiting list of people requiring donated tissues and organs, and generally, supply cannot meet the demand. The total cost to society in terms of caring for patients with failing organs and debilitating diseases is enormous. Scientists and clinicians, motivated by the need to develop safe and reliable sources of tissues and organs, have been improving therapies and technologies that can regenerate tissues and in some cases create new tissues altogether. Tissue engineering and/or regenerative me...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine","attachmentId":79011211,"attachmentType":"pdf","work_url":"https://www.academia.edu/68583690/Advances_in_Regenerative_Medicine_and_Tissue_Engineering_Innovation_and_Transformation_of_Medicine","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/68583690/Advances_in_Regenerative_Medicine_and_Tissue_Engineering_Innovation_and_Transformation_of_Medicine"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="20444403" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/20444403/Tissue_Engineering_Alternative_Option_in_Managing_Large_and_Massive_Tissue_Deficits">Tissue Engineering: Alternative Option in Managing Large and Massive Tissue Deficits</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="15526246" href="https://shirazu.academia.edu/AhmadOryan">Ahmad Oryan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Trop Med Surg, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Tissue Engineering: Alternative Option in Managing Large and Massive Tissue Deficits","attachmentId":41376495,"attachmentType":"pdf","work_url":"https://www.academia.edu/20444403/Tissue_Engineering_Alternative_Option_in_Managing_Large_and_Massive_Tissue_Deficits","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/20444403/Tissue_Engineering_Alternative_Option_in_Managing_Large_and_Massive_Tissue_Deficits"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="103219862" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/103219862/Tissue_engineering_and_surgery_from_translational_studies_to_human_trials">Tissue engineering and surgery: from translational studies to human trials</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58181796" href="https://independent.academia.edu/JanVranckx">Jan Vranckx</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Innovative Surgical Sciences, 2017</p><p class="ds-related-work--abstract ds2-5-body-sm">Tissue engineering was introduced as an innovative and promising field in the mid-1980s. The capacity of cells to migrate and proliferate in growth-inducing medium induced great expectancies on generating custom-shaped bioconstructs for tissue regeneration. Tissue engineering represents a unique multidisciplinary translational forum where the principles of biomaterial engineering, the molecular biology of cells and genes, and the clinical sciences of reconstruction would interact intensively through the combined efforts of scientists, engineers, and clinicians. The anticipated possibilities of cell engineering, matrix development, and growth factor therapies are extensive and would largely expand our clinical reconstructive armamentarium. Application of proangiogenic proteins may stimulate wound repair, restore avascular wound beds, or reverse hypoxia in flaps. Autologous cells procured from biopsies may generate an ‘autologous’ dermal and epidermal laminated cover on extensive burn...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Tissue engineering and surgery: from translational studies to human trials","attachmentId":103284171,"attachmentType":"pdf","work_url":"https://www.academia.edu/103219862/Tissue_engineering_and_surgery_from_translational_studies_to_human_trials","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/103219862/Tissue_engineering_and_surgery_from_translational_studies_to_human_trials"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="123581105" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/123581105/Tissue_Engineering_Current_Status_and_amp_Futuristic_Scope">Tissue Engineering; Current Status &amp; Futuristic Scope</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="172202773" href="https://independent.academia.edu/PDhot">Paramjit Dhot</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of medicine and life, 2019</p><p class="ds-related-work--abstract ds2-5-body-sm">Almost 30 years have passed since the term 'tissue engineering' was created to represent a new concept that focuses on the regeneration of neotissues from cells with the support of biomaterials and growth factors. This interdisciplinary engineering has attracted much attention as a new therapeutic means that may overcome the drawbacks involved in the current artificial organs and organ transplantation that have also been aiming at replacing lost or severely damaged tissues or organs. However, the tissues regenerated by tissue engineering and widely applied to patients are still minimal, including skin, bone, cartilage, capillary, and periodontal tissues. What are the reasons for such slow advances in clinical applications of tissue engineering? This article gives a brief overview of the current state of tissue engineering, covering the fundamentals and applications. The fundamentals of tissue engineering involve cell sources, scaffolds for cell expansion and differentiation, as well as carriers for growth factors. Animal and human trials are a major part of the applications. Based on these results, some critical problems to be resolved for the advances of tissue engineering are addressed from the engineering point of view, emphasizing the close collaboration between medical doctors and biomaterials scientists.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Tissue Engineering; Current Status \u0026amp; Futuristic Scope","attachmentId":117979997,"attachmentType":"pdf","work_url":"https://www.academia.edu/123581105/Tissue_Engineering_Current_Status_and_amp_Futuristic_Scope","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/123581105/Tissue_Engineering_Current_Status_and_amp_Futuristic_Scope"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="97138061" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/97138061/Tissue_Engineering_From_Basic_Sciences_to_Clinical_Perspectives">Tissue Engineering: From Basic Sciences to Clinical Perspectives</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="15180952" href="https://independent.academia.edu/PornanongAramwit">Pornanong Aramwit</a></div><p class="ds-related-work--metadata ds2-5-body-xs">BioMed research international, 2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Tissue Engineering: From Basic Sciences to Clinical Perspectives","attachmentId":98843027,"attachmentType":"pdf","work_url":"https://www.academia.edu/97138061/Tissue_Engineering_From_Basic_Sciences_to_Clinical_Perspectives","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/97138061/Tissue_Engineering_From_Basic_Sciences_to_Clinical_Perspectives"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="124061799" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/124061799/Translational_Research_Methods_Tissue_Engineering_of_the_Kidney_and_Urinary_Tract">Translational Research Methods: Tissue Engineering of the Kidney and Urinary Tract</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="37089582" href="https://independent.academia.edu/AnthonyAtala">Anthony Atala</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Pediatric Nephrology, 2014</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Translational Research Methods: Tissue Engineering of the Kidney and Urinary Tract","attachmentId":118356594,"attachmentType":"pdf","work_url":"https://www.academia.edu/124061799/Translational_Research_Methods_Tissue_Engineering_of_the_Kidney_and_Urinary_Tract","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/124061799/Translational_Research_Methods_Tissue_Engineering_of_the_Kidney_and_Urinary_Tract"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="19385206" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/19385206/Tissue_engineering_in_urology_Where_are_we_going">Tissue engineering in urology: Where are we going?</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="39648603" href="https://independent.academia.edu/AdamMetwalli">Adam Metwalli</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Current Urology Reports, 2003</p><p class="ds-related-work--abstract ds2-5-body-sm">Tissue engineering in urology is a broad term used to describe the development of alternative tissue sources for diseased or dysfunctional native urologic tissue. This article reviews the recently published techniques involving synthetic and natural biodegradable matrices alone, known as &amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;unseeded&amp;amp;amp;amp;amp;amp;amp;amp;amp;quot; scaffolds, and the latest data on &amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;seeded&amp;amp;amp;amp;amp;amp;amp;amp;amp;quot; scaffolds, which are impregnated with cultured cells from urologic organs. Recent discoveries in reporter gene labeling of urologic tissue are discussed as a new method to identify and track the fates of these transplanted cells in vivo. This article also investigates how these bioengineering techniques are applied to synthetic and natural scaffolds, such as polyglycolic acid and porcine small intestine submucosa, to increase bladder capacity, repair urethral strictures, and replace corporal plaques in Peyronie&amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s disease. Furthermore, recently published reports that these materials have been seeded with chondrocytes to create corporal rods for penile prostheses and stents for ureteral and urethral stricture disease are discussed. With these latest developments as a foundation, the future directions of tissue engineering in urology are presented.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Tissue engineering in urology: Where are we going?","attachmentId":42094342,"attachmentType":"pdf","work_url":"https://www.academia.edu/19385206/Tissue_engineering_in_urology_Where_are_we_going","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/19385206/Tissue_engineering_in_urology_Where_are_we_going"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":44440811,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":44440811,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_44440811" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. 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