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Biomolecular Prospecting, Informative Gaps, and the Cancer Clinic: A Qualitative Fieldwork and an Epistemological, Historical and Ethical Analysis of Informed Consent for Clinical Trials for Monoclonal Antibodies and Biobank Research" class="work-thumbnail" src="https://attachments.academia-assets.com/87869288/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/81543333/Biomolecular_Prospecting_Informative_Gaps_and_the_Cancer_Clinic_A_Qualitative_Fieldwork_and_an_Epistemological_Historical_and_Ethical_Analysis_of_Informed_Consent_for_Clinical_Trials_for_Monoclonal_Antibodies_and_Biobank_Research">Biomolecular Prospecting, Informative Gaps, and the Cancer Clinic: A Qualitative Fieldwork and an Epistemological, Historical and Ethical Analysis of Informed Consent for Clinical Trials for Monoclonal Antibodies and Biobank Research</a></div><div class="wp-workCard_item"><span>Frontiers in Genetics</span><span>, 2022</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">What happens to patients with cancer engaged in biomedical research when intellectual property re...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">What happens to patients with cancer engaged in biomedical research when intellectual property regimes and ethical regimes intersect? This qualitative historical study addresses this question by situating the experiences, hopes, and reasons of patients to enter clinical trials within the historical trajectory of informed consent and monoclonal antibodies, the biotechnology underpinning many targeted drugs used in oncological clinical trials and biobank research. Based on fieldwork we undertook in a German university hospital where we interviewed patients and the medical personnel, a historical review, and an ethical analysis we inquire into the effects that financial, legal, and technological changes connected to the relevant pharmaceutical research and commerce have on cancer patients engaged in clinical trials and biobank research. We find that the controversial aspects of monoclonal antibodies, especially those related to the commercial interests at stake, enter the informed consent process mainly in the form of informative gaps. We highlight how a qualitative analysis of the clinic, especially when it is situated against the backdrop of the history of related technological advancements and patent regime, it can serve the purpose of giving voice to subjects who are silenced by regimes of an ethical, epistemic, and commercial kind while pointing to informed consent as an unhelpful device for addressing risks arising from the commercial purposes of biomedical products and infrastructure.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c123a463cd24afdfa5f6459a08cdcb4c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":87869288,"asset_id":81543333,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/87869288/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="81543333"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="81543333"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 81543333; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=81543333]").text(description); $(".js-view-count[data-work-id=81543333]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 81543333; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='81543333']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 81543333, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c123a463cd24afdfa5f6459a08cdcb4c" } } $('.js-work-strip[data-work-id=81543333]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":81543333,"title":"Biomolecular Prospecting, Informative Gaps, and the Cancer Clinic: A Qualitative Fieldwork and an Epistemological, Historical and Ethical Analysis of Informed Consent for Clinical Trials for Monoclonal Antibodies and Biobank Research","translated_title":"","metadata":{"doi":"10.3389/fgene.2022.872211","abstract":"What happens to patients with cancer engaged in biomedical research when intellectual property regimes and ethical regimes intersect? 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href="https://www.academia.edu/81542531/Targeted_drugs_and_Psycho_oncological_intervention_for_breast_cancer_patients"><img alt="Research paper thumbnail of Targeted drugs and Psycho-oncological intervention for breast cancer patients" class="work-thumbnail" src="https://attachments.academia-assets.com/87550401/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/81542531/Targeted_drugs_and_Psycho_oncological_intervention_for_breast_cancer_patients">Targeted drugs and Psycho-oncological intervention for breast cancer patients</a></div><div class="wp-workCard_item"><span>Journal of Negative Results in BioMedicine</span><span>, 2016</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="270c5ae61a7d204ca3ed97d7956ee6d4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":87550401,"asset_id":81542531,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/87550401/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="81542531"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="81542531"><i class="fa fa-spinner 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Psycho-oncology is a complementary approach that considers social and psychological aspects of patients as part of the treatments for cancer patients. The aim of this mini-review is to weigh clinical benefits for breast cancer patients of both treatments and possibily enhance benefits by modulating the use of both interventions. We have compared and evaluated on the one hand the use of anti Vascular Endothelial Growth Factor and, on the other hand, psycho-oncological interventions in metastatic and non-metastatic breast cancer patients. Both treatments did not increase survival of metastatic breast cancer patients, while in a selected study psychooncological interventions extended lifespan of non-metastatic breast cancer patients and ameliorate psychological and social factors of metastatic breast cancer patients. Because the two approaches address completely different aspects of cancer patients, if the comparison is limited to the extension of survival, the value of these two treatments cannot be assessed and compared. It is likely that by comparing patients reported outcomes, possibly by using standardized Quality of Life questionnaires, both patients and health care providers can weigh the benefits of the two treatments. 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Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":257641,"name":"Method Development and Validation of New Drugs","url":"https://www.academia.edu/Documents/in/Method_Development_and_Validation_of_New_Drugs"},{"id":555655,"name":"Bevacizumab","url":"https://www.academia.edu/Documents/in/Bevacizumab"},{"id":1173343,"name":"Precision Medicine","url":"https://www.academia.edu/Documents/in/Precision_Medicine"},{"id":1212103,"name":"Antineoplastic Agents","url":"https://www.academia.edu/Documents/in/Antineoplastic_Agents"},{"id":2847999,"name":"Breast Neoplasms","url":"https://www.academia.edu/Documents/in/Breast_Neoplasms"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="55850941"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/55850941/Political_Epistemology_of_Pandemic_Management"><img alt="Research paper thumbnail of Political Epistemology of Pandemic Management" class="work-thumbnail" src="https://attachments.academia-assets.com/71524581/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/55850941/Political_Epistemology_of_Pandemic_Management">Political Epistemology of Pandemic Management</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unive.academia.edu/GiuliaGandolfi">Giulia Gandolfi</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Today, claims about the contiguity of health management and societal organization bring biopoliti...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Today, claims about the contiguity of health management and societal organization bring biopolitical concerns to the forefront. This essay offers historical-political insights on the covid-19 pandemic, which are particularly urgent, as both the temporal and the cultural-political dimensions have been insufficiently considered in current debates. After introducing our specific political-epistemological approach, we delve into the entanglements of medical expertise, economic interests, surveillance politics, and diplomatic relations in the past in order to shed light on the present. Additionally, we address the limitations of Italian theory's biopolitica, namely its idle radicalization of critical views on medical politics inspired by French épistémologie historique. We conclude with a call to scientists' responsibility in consideration of the societal embedment of their activity. Yet, the task of an emancipated science is not only in their hands but depends on our collective capacity to organically connect their work to the renewal of the body politics at large.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8d9ba6d1aa19ef004d7b7e7d5bf1c281" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":71524581,"asset_id":55850941,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/71524581/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="55850941"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="55850941"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 55850941; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=55850941]").text(description); $(".js-view-count[data-work-id=55850941]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 55850941; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='55850941']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 55850941, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8d9ba6d1aa19ef004d7b7e7d5bf1c281" } } $('.js-work-strip[data-work-id=55850941]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":55850941,"title":"Political Epistemology of Pandemic Management","translated_title":"","metadata":{"abstract":"Today, claims about the contiguity of health management and societal organization bring biopolitical concerns to the forefront. This essay offers historical-political insights on the covid-19 pandemic, which are particularly urgent, as both the temporal and the cultural-political dimensions have been insufficiently considered in current debates. After introducing our specific political-epistemological approach, we delve into the entanglements of medical expertise, economic interests, surveillance politics, and diplomatic relations in the past in order to shed light on the present. Additionally, we address the limitations of Italian theory's biopolitica, namely its idle radicalization of critical views on medical politics inspired by French épistémologie historique. We conclude with a call to scientists' responsibility in consideration of the societal embedment of their activity. Yet, the task of an emancipated science is not only in their hands but depends on our collective capacity to organically connect their work to the renewal of the body politics at large.","ai_title_tag":"Epistemology of Political Pandemic Management and Responsibility","publication_date":{"day":null,"month":null,"year":2021,"errors":{}}},"translated_abstract":"Today, claims about the contiguity of health management and societal organization bring biopolitical concerns to the forefront. This essay offers historical-political insights on the covid-19 pandemic, which are particularly urgent, as both the temporal and the cultural-political dimensions have been insufficiently considered in current debates. After introducing our specific political-epistemological approach, we delve into the entanglements of medical expertise, economic interests, surveillance politics, and diplomatic relations in the past in order to shed light on the present. Additionally, we address the limitations of Italian theory's biopolitica, namely its idle radicalization of critical views on medical politics inspired by French épistémologie historique. We conclude with a call to scientists' responsibility in consideration of the societal embedment of their activity. Yet, the task of an emancipated science is not only in their hands but depends on our collective capacity to organically connect their work to the renewal of the body politics at large.","internal_url":"https://www.academia.edu/55850941/Political_Epistemology_of_Pandemic_Management","translated_internal_url":"","created_at":"2021-10-06T00:42:19.607-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":18545515,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":36953941,"work_id":55850941,"tagging_user_id":18545515,"tagged_user_id":33984,"co_author_invite_id":null,"email":"c***1@gmail.com","affiliation":"Université Toulouse II Jean Jaurès","display_order":1,"name":"Charles Wolfe","title":"Political Epistemology of Pandemic Management"},{"id":36953942,"work_id":55850941,"tagging_user_id":18545515,"tagged_user_id":1034863,"co_author_invite_id":null,"email":"g***a@gmail.com","affiliation":"Università di Verona","display_order":2,"name":"Gerardo Ienna","title":"Political Epistemology of Pandemic Management"},{"id":36953943,"work_id":55850941,"tagging_user_id":18545515,"tagged_user_id":1231121,"co_author_invite_id":null,"email":"f***o@gmail.com","affiliation":"Università degli Studi di Scienze Gastronomiche di Pollenzo","display_order":3,"name":"Flavio D'Abramo","title":"Political Epistemology of Pandemic Management"},{"id":36953944,"work_id":55850941,"tagging_user_id":18545515,"tagged_user_id":null,"co_author_invite_id":7315293,"email":"f***o@mpiwg-berlin.mpg.de","display_order":4,"name":"Flavio D'Abramo","title":"Political Epistemology of Pandemic Management"}],"downloadable_attachments":[{"id":71524581,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/71524581/thumbnails/1.jpg","file_name":"Political_Epistemology_of_Pandemic_Manag.pdf","download_url":"https://www.academia.edu/attachments/71524581/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Political_Epistemology_of_Pandemic_Manag.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/71524581/Political_Epistemology_of_Pandemic_Manag-libre.pdf?1633507584=\u0026response-content-disposition=attachment%3B+filename%3DPolitical_Epistemology_of_Pandemic_Manag.pdf\u0026Expires=1732833149\u0026Signature=MwrxzBbGNRPZaKD6Xgu0bUhgp8M~szX8lY~d4tC7bOtOpovT2nYtzTR7dFzuqyS0Nr0~xOSNBYgKxBWyPagJN2mNlNhKEB0jXSvTLIRXIIaz6EaeAi7Wh2TIaVEQxeT4I9MvJaQ6E1xx1aGB6IiilGMMtD19EFDT8cGk3m9dnWtmMJKqyuDeI6R6Dh~-Wc~zDL7UOSBz9MsE3mI0M1uO5ChIcymmc7TErK4pVrA3rY2hTg8OUmx3u3lDgT1TaCvjI2gRnmaWMW0JHsfe126KrbY5-rM8P7vGRLhnDm7~VyON~AsDx9wrAmfUJOJ8B1~IXsePwHT7f6MhMddqxefhqg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Political_Epistemology_of_Pandemic_Management","translated_slug":"","page_count":17,"language":"en","content_type":"Work","owner":{"id":18545515,"first_name":"Giulia","middle_initials":null,"last_name":"Gandolfi","page_name":"GiuliaGandolfi","domain_name":"unive","created_at":"2014-10-11T10:05:52.377-07:00","display_name":"Giulia Gandolfi","url":"https://unive.academia.edu/GiuliaGandolfi"},"attachments":[{"id":71524581,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/71524581/thumbnails/1.jpg","file_name":"Political_Epistemology_of_Pandemic_Manag.pdf","download_url":"https://www.academia.edu/attachments/71524581/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Political_Epistemology_of_Pandemic_Manag.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/71524581/Political_Epistemology_of_Pandemic_Manag-libre.pdf?1633507584=\u0026response-content-disposition=attachment%3B+filename%3DPolitical_Epistemology_of_Pandemic_Manag.pdf\u0026Expires=1732833149\u0026Signature=MwrxzBbGNRPZaKD6Xgu0bUhgp8M~szX8lY~d4tC7bOtOpovT2nYtzTR7dFzuqyS0Nr0~xOSNBYgKxBWyPagJN2mNlNhKEB0jXSvTLIRXIIaz6EaeAi7Wh2TIaVEQxeT4I9MvJaQ6E1xx1aGB6IiilGMMtD19EFDT8cGk3m9dnWtmMJKqyuDeI6R6Dh~-Wc~zDL7UOSBz9MsE3mI0M1uO5ChIcymmc7TErK4pVrA3rY2hTg8OUmx3u3lDgT1TaCvjI2gRnmaWMW0JHsfe126KrbY5-rM8P7vGRLhnDm7~VyON~AsDx9wrAmfUJOJ8B1~IXsePwHT7f6MhMddqxefhqg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":803,"name":"Philosophy","url":"https://www.academia.edu/Documents/in/Philosophy"},{"id":8424,"name":"Georges Canguilhem","url":"https://www.academia.edu/Documents/in/Georges_Canguilhem"},{"id":9535,"name":"Giorgio Agamben","url":"https://www.academia.edu/Documents/in/Giorgio_Agamben"},{"id":11927,"name":"Michel Foucault","url":"https://www.academia.edu/Documents/in/Michel_Foucault"},{"id":16323,"name":"Biopolitics","url":"https://www.academia.edu/Documents/in/Biopolitics"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="50276823"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/50276823/Antibiotic_resistance_planetary_health_and_the_mimetic_trap_A_historical_account_of_present_day_sanitary_environmental_and_social_crises"><img alt="Research paper thumbnail of Antibiotic resistance, planetary health and the mimetic trap: A historical account of present-day sanitary, environmental and social crises" class="work-thumbnail" src="https://attachments.academia-assets.com/68829519/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/50276823/Antibiotic_resistance_planetary_health_and_the_mimetic_trap_A_historical_account_of_present_day_sanitary_environmental_and_social_crises">Antibiotic resistance, planetary health and the mimetic trap: A historical account of present-day sanitary, environmental and social crises</a></div><div class="wp-workCard_item"><span>Postcolonial Studies</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The industrialisation of food production over the past century has triggered a series of sanitary...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The industrialisation of food production over the past century has triggered a series of sanitary crises related to antibiotic resistance. In this article, I contend that to understand the radical transformation of animal farming and its effects on public health, we need to inquire into the historical development of the knowledge on microbes, especially with regard to the agricultural industry’s mobilisation and repression of microbial metabolism to scale up food production. Moreover, I conceive of the so-called Great Acceleration of the Anthropocene as a postcolonial mimetic trap through which actors who didn’t play an active role in the contemporary ecological collapse are subsumed into an indistinct “we”. To disentangle this alleged collective subject created from accounts of planetary health, I focus on the scientific, social, and institutional histories of antibiotic production and antibiotic use that materialised in the epidemiological issue of antibiotic resistance. Furthermore, I highlight how the history of antibiotic use and resistance is intertwined with the ecological, social, and geopolitical dynamics created by intense industrial production and international rivalries during the Cold War. This article calls for the re-evaluation and creation of counter-narratives of the planetary impact of industry on microbes, local communities, patients, medical personnel, and the global poor.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="81fc811ae8301cfa5679bfdef5b6491e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":68829519,"asset_id":50276823,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/68829519/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="50276823"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="50276823"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 50276823; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=50276823]").text(description); $(".js-view-count[data-work-id=50276823]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 50276823; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='50276823']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 50276823, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "81fc811ae8301cfa5679bfdef5b6491e" } } $('.js-work-strip[data-work-id=50276823]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":50276823,"title":"Antibiotic resistance, planetary health and the mimetic trap: A historical account of present-day sanitary, environmental and social crises","translated_title":"","metadata":{"doi":"10.1080/13688790.2021.1963093","abstract":"The industrialisation of food production over the past century has triggered a series of sanitary crises related to antibiotic resistance. 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Furthermore, I highlight how the history of antibiotic use and resistance is intertwined with the ecological, social, and geopolitical dynamics created by intense industrial production and international rivalries during the Cold War. This article calls for the re-evaluation and creation of counter-narratives of the planetary impact of industry on microbes, local communities, patients, medical personnel, and the global poor.","publication_date":{"day":null,"month":null,"year":2021,"errors":{}},"publication_name":"Postcolonial Studies"},"translated_abstract":"The industrialisation of food production over the past century has triggered a series of sanitary crises related to antibiotic resistance. In this article, I contend that to understand the radical transformation of animal farming and its effects on public health, we need to inquire into the historical development of the knowledge on microbes, especially with regard to the agricultural industry’s mobilisation and repression of microbial metabolism to scale up food production. Moreover, I conceive of the so-called Great Acceleration of the Anthropocene as a postcolonial mimetic trap through which actors who didn’t play an active role in the contemporary ecological collapse are subsumed into an indistinct “we”. To disentangle this alleged collective subject created from accounts of planetary health, I focus on the scientific, social, and institutional histories of antibiotic production and antibiotic use that materialised in the epidemiological issue of antibiotic resistance. Furthermore, I highlight how the history of antibiotic use and resistance is intertwined with the ecological, social, and geopolitical dynamics created by intense industrial production and international rivalries during the Cold War. This article calls for the re-evaluation and creation of counter-narratives of the planetary impact of industry on microbes, local communities, patients, medical personnel, and the global poor.","internal_url":"https://www.academia.edu/50276823/Antibiotic_resistance_planetary_health_and_the_mimetic_trap_A_historical_account_of_present_day_sanitary_environmental_and_social_crises","translated_internal_url":"","created_at":"2021-07-26T10:33:44.588-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"draft","co_author_tags":[],"downloadable_attachments":[{"id":68829519,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/68829519/thumbnails/1.jpg","file_name":"Open_Access_Link.pdf","download_url":"https://www.academia.edu/attachments/68829519/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Antibiotic_resistance_planetary_health_a.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/68829519/Open_Access_Link-libre.pdf?1629531912=\u0026response-content-disposition=attachment%3B+filename%3DAntibiotic_resistance_planetary_health_a.pdf\u0026Expires=1732799329\u0026Signature=JrAEnczXYf-o6XYSZzwszCoufH060hQ5zQJrY1u9yumm5r2BesDPe3zo4bn8TugylFHkrYq7f91uykULnZf4ZBlW-fBP7-HXfRgYTydZ3Z-EmvxNWBeIkTgxdQR6yl0j~Sf0qFXdQR4OU52KzvFd~E8KfXaoAC40FKrBFGW4~h2Xqk3wkEcv68p3koY9KwIj0NFU2svn3BkAdANCIskX3pTNPSKRSBdECEjqvMy7HIFjOTSOEqLkjorhurL-Fb6Ze21nU1DaKL6BPRBvAGYo-pzvLFEeTck-lN1j4Mhxaxu-MhmWxFM99tAfFbMJtfOJD-n31~59TISCWVhZnpYylQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Antibiotic_resistance_planetary_health_and_the_mimetic_trap_A_historical_account_of_present_day_sanitary_environmental_and_social_crises","translated_slug":"","page_count":1,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[{"id":68829519,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/68829519/thumbnails/1.jpg","file_name":"Open_Access_Link.pdf","download_url":"https://www.academia.edu/attachments/68829519/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Antibiotic_resistance_planetary_health_a.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/68829519/Open_Access_Link-libre.pdf?1629531912=\u0026response-content-disposition=attachment%3B+filename%3DAntibiotic_resistance_planetary_health_a.pdf\u0026Expires=1732799329\u0026Signature=JrAEnczXYf-o6XYSZzwszCoufH060hQ5zQJrY1u9yumm5r2BesDPe3zo4bn8TugylFHkrYq7f91uykULnZf4ZBlW-fBP7-HXfRgYTydZ3Z-EmvxNWBeIkTgxdQR6yl0j~Sf0qFXdQR4OU52KzvFd~E8KfXaoAC40FKrBFGW4~h2Xqk3wkEcv68p3koY9KwIj0NFU2svn3BkAdANCIskX3pTNPSKRSBdECEjqvMy7HIFjOTSOEqLkjorhurL-Fb6Ze21nU1DaKL6BPRBvAGYo-pzvLFEeTck-lN1j4Mhxaxu-MhmWxFM99tAfFbMJtfOJD-n31~59TISCWVhZnpYylQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":5214,"name":"Cold War","url":"https://www.academia.edu/Documents/in/Cold_War"},{"id":7403,"name":"Environmental Health","url":"https://www.academia.edu/Documents/in/Environmental_Health"},{"id":18590,"name":"Environmental Justice","url":"https://www.academia.edu/Documents/in/Environmental_Justice"},{"id":35620,"name":"Antibiotic Resistance","url":"https://www.academia.edu/Documents/in/Antibiotic_Resistance"},{"id":60740,"name":"Zoonosis","url":"https://www.academia.edu/Documents/in/Zoonosis"},{"id":149474,"name":"Anthropocene","url":"https://www.academia.edu/Documents/in/Anthropocene"},{"id":521881,"name":"World Health Organization","url":"https://www.academia.edu/Documents/in/World_Health_Organization"},{"id":2528113,"name":"History of Antibiotics","url":"https://www.academia.edu/Documents/in/History_of_Antibiotics"}],"urls":[{"id":10731048,"url":"https://www.tandfonline.com/doi/full/10.1080/13688790.2021.1963093"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="49025352"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/49025352/The_past_and_present_of_pandemic_management_health_diplomacy_international_epidemiological_surveillance_and_COVID_19"><img alt="Research paper thumbnail of The past and present of pandemic management: health diplomacy, international epidemiological surveillance, and COVID‑19" class="work-thumbnail" src="https://attachments.academia-assets.com/67410154/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/49025352/The_past_and_present_of_pandemic_management_health_diplomacy_international_epidemiological_surveillance_and_COVID_19">The past and present of pandemic management: health diplomacy, international epidemiological surveillance, and COVID‑19</a></div><div class="wp-workCard_item"><span>History and Philosophy of the Life Sciences</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The establishment of international sanitary institutions, which took place in the context of riva...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The establishment of international sanitary institutions, which took place in the context of rivalry among the great European powers and their colonial expan-sion in Asia, allowed for the development of administrative systems of international epidemiological surveillance as a response to the cholera epidemics at the end of the nineteenth century. In this note, I reflect on how a historical analysis of the inception of international epidemiological surveillance and pandemic management helps us to understand what is happening in the COVID-19 pandemic today.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="12c2c9adbbc017d5f0433cdced5cbc47" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":67410154,"asset_id":49025352,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/67410154/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="49025352"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="49025352"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 49025352; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=49025352]").text(description); $(".js-view-count[data-work-id=49025352]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 49025352; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='49025352']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 49025352, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "12c2c9adbbc017d5f0433cdced5cbc47" } } $('.js-work-strip[data-work-id=49025352]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":49025352,"title":"The past and present of pandemic management: health diplomacy, international epidemiological surveillance, and COVID‑19","translated_title":"","metadata":{"doi":"10.1007/s40656-021-00416-4","abstract":"The establishment of international sanitary institutions, which took place in the context of rivalry among the great European powers and their colonial expan-sion in Asia, allowed for the development of administrative systems of international epidemiological surveillance as a response to the cholera epidemics at the end of the nineteenth century. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="43652254"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/43652254/A_Historical_and_Political_Epistemology_of_Microbes"><img alt="Research paper thumbnail of A Historical and Political Epistemology of Microbes" class="work-thumbnail" src="https://attachments.academia-assets.com/63977964/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/43652254/A_Historical_and_Political_Epistemology_of_Microbes">A Historical and Political Epistemology of Microbes</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/SybilleNeumeyer">Sybille Neumeyer</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a></span></div><div class="wp-workCard_item"><span>Centaurus</span><span>, 2020</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">This article traces the historical co-evolution of microbiology, bacteriology, and virology, fram...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">This article traces the historical co-evolution of microbiology, bacteriology, and virology, framed within industrial and agricultural contexts, as well as their role in colonial and national history between the end of the 19th century and the first decades of the 20th century. The epistemology of germ theory, coupled with the economic interests of European colonies, has shaped the understanding of human-microbial relationships in a reductionist way. We explore a brief history of the medical and biological sciences, focusing on microbes and the difficulty of implementing germ theory outside of biology laboratories. Furthermore, we highlight the work of Lynn Margulis, who conceptualized microbes within their ecological contexts. Such research shows the active role microbes play in handling life-sustaining biological and biochemical processes. We outline how the industrial and technological advancements of the last two centuries not only impacted almost all human societies, but also changed the world on microbial, biological, and geological levels. The narration of these histories is a complex task, and depends on how national, international, and intergovernmental institutions (such as the World Health Organization) conceive of the selective environmental pressures exerted by industry and biotechnological companies.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c4cc213175fec2020eab1f2bbe57c7d7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":63977964,"asset_id":43652254,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/63977964/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="43652254"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="43652254"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 43652254; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=43652254]").text(description); $(".js-view-count[data-work-id=43652254]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 43652254; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='43652254']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 43652254, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c4cc213175fec2020eab1f2bbe57c7d7" } } $('.js-work-strip[data-work-id=43652254]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":43652254,"title":"A Historical and Political Epistemology of Microbes","translated_title":"","metadata":{"doi":"10.1111/1600-0498.12300","volume":"62","abstract":"This article traces the historical co-evolution of microbiology, bacteriology, and virology, framed within industrial and agricultural contexts, as well as their role in colonial and national history between the end of the 19th century and the first decades of the 20th century. 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We explore a brief history of the medical and biological sciences, focusing on microbes and the difficulty of implementing germ theory outside of biology laboratories. Furthermore, we highlight the work of Lynn Margulis, who conceptualized microbes within their ecological contexts. Such research shows the active role microbes play in handling life-sustaining biological and biochemical processes. We outline how the industrial and technological advancements of the last two centuries not only impacted almost all human societies, but also changed the world on microbial, biological, and geological levels. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="39769580"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/39769580/Anthropocene_in_the_cell"><img alt="Research paper thumbnail of Anthropocene in the cell" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/39769580/Anthropocene_in_the_cell">Anthropocene in the cell</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://ucla.academia.edu/HannahLandecker">Hannah Landecker</a></span></div><div class="wp-workCard_item"><span>Technosphere Magazine, Dossier # Substances</span><span>, 2019</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">What does it take for the life sciences to reflect on themselves and their conceptual models in t...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">What does it take for the life sciences to reflect on themselves and their conceptual models in the era of the technosphere? In this conversation, sociologist Hannah Landecker and historian of science Flavio D’Abramo discuss the drastic shifts in our understandings of body-environment dynamics made visible by recent insights within the fields of epidemiology and epigenetics. They point to the necessity of reflecting on the limits of the organism itself, given the ways in which the social, ecological, and multi-species environments are intertwined with the biological one.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="39769580"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="39769580"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 39769580; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=39769580]").text(description); $(".js-view-count[data-work-id=39769580]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 39769580; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='39769580']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 39769580, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=39769580]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":39769580,"title":"Anthropocene in the cell","translated_title":"","metadata":{"abstract":"What does it take for the life sciences to reflect on themselves and their conceptual models in the era of the technosphere? 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They point to the necessity of reflecting on the limits of the organism itself, given the ways in which the social, ecological, and multi-species environments are intertwined with the biological one.","internal_url":"https://www.academia.edu/39769580/Anthropocene_in_the_cell","translated_internal_url":"","created_at":"2019-07-07T14:01:47.802-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":32794138,"work_id":39769580,"tagging_user_id":1231121,"tagged_user_id":31304507,"co_author_invite_id":null,"email":"l***r@soc.ucla.edu","affiliation":"University of California, Los Angeles","display_order":0,"name":"Hannah Landecker","title":"Anthropocene in the cell"}],"downloadable_attachments":[],"slug":"Anthropocene_in_the_cell","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[],"research_interests":[{"id":823,"name":"Philosophy of Biology","url":"https://www.academia.edu/Documents/in/Philosophy_of_Biology"},{"id":1083,"name":"Developmental Biology","url":"https://www.academia.edu/Documents/in/Developmental_Biology"},{"id":1085,"name":"Epidemiology","url":"https://www.academia.edu/Documents/in/Epidemiology"},{"id":1512,"name":"Climate Change","url":"https://www.academia.edu/Documents/in/Climate_Change"},{"id":3407,"name":"Environmental Studies","url":"https://www.academia.edu/Documents/in/Environmental_Studies"},{"id":7076,"name":"Taxonomy","url":"https://www.academia.edu/Documents/in/Taxonomy"},{"id":9846,"name":"Ecology","url":"https://www.academia.edu/Documents/in/Ecology"},{"id":13075,"name":"History of Biology","url":"https://www.academia.edu/Documents/in/History_of_Biology"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"},{"id":22404,"name":"Epigenetics","url":"https://www.academia.edu/Documents/in/Epigenetics"},{"id":26898,"name":"Ecological Developmental Biology","url":"https://www.academia.edu/Documents/in/Ecological_Developmental_Biology"},{"id":35620,"name":"Antibiotic Resistance","url":"https://www.academia.edu/Documents/in/Antibiotic_Resistance"},{"id":39738,"name":"Anthropocene studies","url":"https://www.academia.edu/Documents/in/Anthropocene_studies"},{"id":53944,"name":"Gut Microbiome","url":"https://www.academia.edu/Documents/in/Gut_Microbiome"},{"id":53948,"name":"Human Microbiome","url":"https://www.academia.edu/Documents/in/Human_Microbiome"},{"id":149474,"name":"Anthropocene","url":"https://www.academia.edu/Documents/in/Anthropocene"},{"id":781620,"name":"Culture and the Anthropocene","url":"https://www.academia.edu/Documents/in/Culture_and_the_Anthropocene"}],"urls":[{"id":8826671,"url":"https://technosphere-magazine.hkw.de/p/Anthropocene-in-the-Cell-fQjoLLgrE7jbXzLYr1TLNn"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="36805309"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/36805309/The_bench_is_closer_to_the_bedside_than_we_think_Uncovering_the_ethical_ties_between_preclinical_researchers_in_translational_neuroscience_and_patients_in_clinical_trials"><img alt="Research paper thumbnail of The bench is closer to the bedside than we think: Uncovering the ethical ties between preclinical researchers in translational neuroscience and patients in clinical trials" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/36805309/The_bench_is_closer_to_the_bedside_than_we_think_Uncovering_the_ethical_ties_between_preclinical_researchers_in_translational_neuroscience_and_patients_in_clinical_trials">The bench is closer to the bedside than we think: Uncovering the ethical ties between preclinical researchers in translational neuroscience and patients in clinical trials</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Millions of people worldwide currently suffer from serious neurological diseases and injuries for...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Millions of people worldwide currently suffer from serious neurological diseases and injuries for which there are few, and often no, effective treatments. The paucity of effective interventions is, no doubt, due in large part to the complexity of the disorders, as well as our currently limited understanding of their pathophysiology. The bleak picture for patients, however, is also attributable to avoidable impediments stemming from quality concerns in preclinical research that often escape detection by research regulation efforts. In our essay, we connect the dots between these concerns about the quality of preclinical research and their potential ethical impact on the patients who volunteer for early trials of interventions informed by it. We do so in hopes that a greater appreciation among preclinical researchers of these serious ethical consequences can lead to a greater commitment within the research community to adopt widely available tools and measures that can help to improve the quality of research.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="36805309"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="36805309"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 36805309; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=36805309]").text(description); $(".js-view-count[data-work-id=36805309]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 36805309; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='36805309']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 36805309, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=36805309]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":36805309,"title":"The bench is closer to the bedside than we think: Uncovering the ethical ties between preclinical researchers in translational neuroscience and patients in clinical trials","translated_title":"","metadata":{"abstract":"Millions of people worldwide currently suffer from serious neurological diseases and injuries for which there are few, and often no, effective treatments. The paucity of effective interventions is, no doubt, due in large part to the complexity of the disorders, as well as our currently limited understanding of their pathophysiology. The bleak picture for patients, however, is also attributable to avoidable impediments stemming from quality concerns in preclinical research that often escape detection by research regulation efforts. In our essay, we connect the dots between these concerns about the quality of preclinical research and their potential ethical impact on the patients who volunteer for early trials of interventions informed by it. We do so in hopes that a greater appreciation among preclinical researchers of these serious ethical consequences can lead to a greater commitment within the research community to adopt widely available tools and measures that can help to improve the quality of research."},"translated_abstract":"Millions of people worldwide currently suffer from serious neurological diseases and injuries for which there are few, and often no, effective treatments. The paucity of effective interventions is, no doubt, due in large part to the complexity of the disorders, as well as our currently limited understanding of their pathophysiology. The bleak picture for patients, however, is also attributable to avoidable impediments stemming from quality concerns in preclinical research that often escape detection by research regulation efforts. In our essay, we connect the dots between these concerns about the quality of preclinical research and their potential ethical impact on the patients who volunteer for early trials of interventions informed by it. We do so in hopes that a greater appreciation among preclinical researchers of these serious ethical consequences can lead to a greater commitment within the research community to adopt widely available tools and measures that can help to improve the quality of research.","internal_url":"https://www.academia.edu/36805309/The_bench_is_closer_to_the_bedside_than_we_think_Uncovering_the_ethical_ties_between_preclinical_researchers_in_translational_neuroscience_and_patients_in_clinical_trials","translated_internal_url":"","created_at":"2018-06-08T03:03:10.703-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_bench_is_closer_to_the_bedside_than_we_think_Uncovering_the_ethical_ties_between_preclinical_researchers_in_translational_neuroscience_and_patients_in_clinical_trials","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[],"research_interests":[{"id":9435,"name":"Medical Ethics","url":"https://www.academia.edu/Documents/in/Medical_Ethics"},{"id":608787,"name":"Ethics in Scientific Publication","url":"https://www.academia.edu/Documents/in/Ethics_in_Scientific_Publication"}],"urls":[{"id":8516907,"url":"http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2006343\u0026utm_source=feedburner\u0026utm_medium=feed\u0026utm_campaign=Feed:+plosbiology/NewArticles+(PLOS+Biology+-+New+Articles)"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33940317"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33940317/Health_wealth_and_behavioural_change_an_exploration_of_role_responsibilities_in_the_wake_of_epigenetics"><img alt="Research paper thumbnail of Health, wealth and behavioural change: an exploration of role responsibilities in the wake of epigenetics" class="work-thumbnail" src="https://attachments.academia-assets.com/53972427/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33940317/Health_wealth_and_behavioural_change_an_exploration_of_role_responsibilities_in_the_wake_of_epigenetics">Health, wealth and behavioural change: an exploration of role responsibilities in the wake of epigenetics</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/DanyaFVears">Danya F. Vears</a></span></div><div class="wp-workCard_item"><span>Journal of Community Genetics</span><span>, 2017</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The field of epigenetics is leading to new conceptualizations of the role of environmental factor...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The field of epigenetics is leading to new conceptualizations of the role of environmental factors in health and genetic disease. Although more evidence is required, epigenetic mechanisms are being implicated in the link between low socioeconomic status and poor health status. Epigenetic phenomena work in a number of ways: they can be established early in development, transmitted from previous generations and/or responsive to environmental factors. Knowledge about these types of epigenetic traits might therefore allow us to move away from a genetic deterministic perspective, and provide individuals with the opportunity to change their health status. Although this could be equated with patient empowerment, it could also lead to stigmatization and discrimination where individuals are deemed responsible for their health, even if they are not in social situations where they are able to enact change that would alter their health status. In this paper, we will explore the responsibilities of different actors in the healthcare sphere in relation to epigenetics across four different contexts: (1) genetic research, (2) clinical practice, (3) prenatal care and (4) the workplace. Within this exploration of role responsibilities, we will also discuss the potential constraints that might prevent the patient, mother-to-be, research participant or employee, from enacting any necessary steps in order to increase their health status in response to epigenetic information.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="04698566bdf57d993925248cd1477537" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53972427,"asset_id":33940317,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53972427/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33940317"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33940317"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33940317; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33940317]").text(description); $(".js-view-count[data-work-id=33940317]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33940317; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33940317']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 33940317, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "04698566bdf57d993925248cd1477537" } } $('.js-work-strip[data-work-id=33940317]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33940317,"title":"Health, wealth and behavioural change: an exploration of role responsibilities in the wake of epigenetics","translated_title":"","metadata":{"doi":"10.1007/s12687-017-0315-7","abstract":"The field of epigenetics is leading to new conceptualizations of the role of environmental factors in health and genetic disease. 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In this paper, we will explore the responsibilities of different actors in the healthcare sphere in relation to epigenetics across four different contexts: (1) genetic research, (2) clinical practice, (3) prenatal care and (4) the workplace. Within this exploration of role responsibilities, we will also discuss the potential constraints that might prevent the patient, mother-to-be, research participant or employee, from enacting any necessary steps in order to increase their health status in response to epigenetic information.","page_numbers":"1-15","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"Journal of Community Genetics"},"translated_abstract":"The field of epigenetics is leading to new conceptualizations of the role of environmental factors in health and genetic disease. Although more evidence is required, epigenetic mechanisms are being implicated in the link between low socioeconomic status and poor health status. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="23943968"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/23943968/Targeted_drugs_and_Psycho_oncological_intervention_for_breast_cancer_patients"><img alt="Research paper thumbnail of Targeted drugs and Psycho-oncological intervention for breast cancer patients" class="work-thumbnail" src="https://attachments.academia-assets.com/44328973/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/23943968/Targeted_drugs_and_Psycho_oncological_intervention_for_breast_cancer_patients">Targeted drugs and Psycho-oncological intervention for breast cancer patients</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/CeciliaGuastadisegni">Cecilia Guastadisegni</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/UteGoerling">Ute Goerling</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Personalized medicine is a new field based on molecular biology and genomics in which targeted tu...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Personalized medicine is a new field based on molecular biology and genomics in which targeted tumor therapies are administered to patients. Psycho-oncology is a complementary approach that considers social and psychological aspects of patients as part of the treatments for cancer patients.<br /><br />The aim of this mini-review is to weigh clinical benefits for breast cancer patients of both treatments and possibily enhance benefits by modulating the use of both interventions. We have compared and evaluated on the one hand the use of anti Vascular Endothelial Growth Factor and, on the other hand, psycho-oncological interventions in metastatic and non-metastatic breast cancer patients.<br /><br />Both treatments did not increase survival of metastatic breast cancer patients, while in a selected study psycho-oncological interventions extended lifespan of non-metastatic breast cancer patients and ameliorate psychological and social factors of metastatic breast cancer patients. Because the two approaches address completely different aspects of cancer patients, if the comparison is limited to the extension of survival, the value of these two treatments cannot be assessed and compared.<br /><br />It is likely that by comparing patients reported outcomes, possibly by using standardized Quality of Life questionnaires, both patients and health care providers can weigh the benefits of the two treatments. It is therefore important to evaluate the use of cancer patients’ quality of life measures as a mean to improve their experiences about life and treatment, and possibly to extend their survival.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c381eb22b0837e05f4686bb9b4ff405e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44328973,"asset_id":23943968,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44328973/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="23943968"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="23943968"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 23943968; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=23943968]").text(description); $(".js-view-count[data-work-id=23943968]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 23943968; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='23943968']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 23943968, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c381eb22b0837e05f4686bb9b4ff405e" } } $('.js-work-strip[data-work-id=23943968]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":23943968,"title":"Targeted drugs and Psycho-oncological intervention for breast cancer patients","translated_title":"","metadata":{"abstract":"Personalized medicine is a new field based on molecular biology and genomics in which targeted tumor therapies are administered to patients. Psycho-oncology is a complementary approach that considers social and psychological aspects of patients as part of the treatments for cancer patients.\n\nThe aim of this mini-review is to weigh clinical benefits for breast cancer patients of both treatments and possibily enhance benefits by modulating the use of both interventions. We have compared and evaluated on the one hand the use of anti Vascular Endothelial Growth Factor and, on the other hand, psycho-oncological interventions in metastatic and non-metastatic breast cancer patients.\n\nBoth treatments did not increase survival of metastatic breast cancer patients, while in a selected study psycho-oncological interventions extended lifespan of non-metastatic breast cancer patients and ameliorate psychological and social factors of metastatic breast cancer patients. Because the two approaches address completely different aspects of cancer patients, if the comparison is limited to the extension of survival, the value of these two treatments cannot be assessed and compared.\n\nIt is likely that by comparing patients reported outcomes, possibly by using standardized Quality of Life questionnaires, both patients and health care providers can weigh the benefits of the two treatments. It is therefore important to evaluate the use of cancer patients’ quality of life measures as a mean to improve their experiences about life and treatment, and possibly to extend their survival."},"translated_abstract":"Personalized medicine is a new field based on molecular biology and genomics in which targeted tumor therapies are administered to patients. 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Because the two approaches address completely different aspects of cancer patients, if the comparison is limited to the extension of survival, the value of these two treatments cannot be assessed and compared.\n\nIt is likely that by comparing patients reported outcomes, possibly by using standardized Quality of Life questionnaires, both patients and health care providers can weigh the benefits of the two treatments. 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class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/22552525/Samples_and_data_accessibility_in_research_biobanks_an_explorative_survey"><img alt="Research paper thumbnail of Samples and data accessibility in research biobanks: an explorative survey" class="work-thumbnail" src="https://attachments.academia-assets.com/43165905/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/22552525/Samples_and_data_accessibility_in_research_biobanks_an_explorative_survey">Samples and data accessibility in research biobanks: an explorative survey</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Biobanks, which contain human biological samples and/or data, provide a crucial contribution to t...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Biobanks, which contain human biological samples and/or data, provide a crucial contribution to the progress of biomedical research. However, the effective and efficient use of biobank resources depends on their accessibility. In fact, making bio-resources promptly accessible to everybody may increase the benefits for society. Furthermore, optimizing their use and ensuring their quality will promote scientific creativity and, in general, contribute to the progress of bio-medical research. Although this has become a rather common belief, several laboratories are still secretive and continue to withhold samples and data. In this study, we conducted a questionnaire-<br />based survey in order to investigate sample and data accessibility in research biobanks operating all over the world. The survey involved a total of 46 biobanks. Most of them gave permission to access their samples (95.7%) and data (85.4%), but free and<br />unconditioned accessibility seemed not to be common practice. The analysis of the guidelines regarding the accessibility to resources of the biobanks that responded to the survey highlights three issues: (i) the request for applicants to explain what they would like to do with the resources requested; (ii) the role of funding, public or private, in the establishment of fruitful collaborations between biobanks and research labs; (iii)<br />the request of co-authorship in order to give access to their data. These results suggest that economic and academic aspects are involved in determining the extent of sample and data sharing stored in biobanks. As a second step of this study, we investigated<br />the reasons behind the high diversity of requirements to access biobank resources. The analysis of informative answers suggested that the different modalities of resource accessibility seem to be largely influenced by both social context and legislation of the countries where the biobanks operate.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8d68b4c962e74cf4b9e93c520c2ab9bb" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":43165905,"asset_id":22552525,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/43165905/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="22552525"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="22552525"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22552525; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22552525]").text(description); $(".js-view-count[data-work-id=22552525]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 22552525; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='22552525']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 22552525, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8d68b4c962e74cf4b9e93c520c2ab9bb" } } $('.js-work-strip[data-work-id=22552525]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":22552525,"title":"Samples and data accessibility in research biobanks: an explorative survey","translated_title":"","metadata":{"abstract":"Biobanks, which contain human biological samples and/or data, provide a crucial contribution to the progress of biomedical research. 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resources? The case of research biobanks" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/20489646/Sharing_standards_before_sharing_resources_The_case_of_research_biobanks">Sharing standards before sharing resources? The case of research biobanks</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In biobank research, one of the main obstacles for full applicability of Open Access to biomedica...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In biobank research, one of the main obstacles for full applicability of Open Access to biomedical resources is the researchers’ reluctance to make immediately and freely available these materials before having adequately exploited their potential. To analyse this issue from a wider perspective, we need to consider the role of research biobanks as main repositories in which human biological samples are stored, with or without accompanying them with genetic or clinical data (Haga and Beskow 2008). If withholding of biobanks’ resources drastically reduces their full value, their wide sharing is not simple to put into practice. The first and most complex barrier hindering Open Access is the lack of common standards, guidelines and legal frameworks due to socio-cultural differences of countries where biobanks operate (see Capocasa et al 2015 <a href="https://peerj.com/preprints/1212/" rel="nofollow">https://peerj.com/preprints/1212/</a>). Developing harmonised standards is a challenge that primarily needs to foster international norms for donors’ p...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="20489646"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="20489646"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 20489646; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20489646]").text(description); $(".js-view-count[data-work-id=20489646]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20489646; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='20489646']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 20489646, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=20489646]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":20489646,"title":"Sharing standards before sharing resources? 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Developing harmonised standards is a challenge that primarily needs to foster international norms for donors’ p..."},"translated_abstract":"In biobank research, one of the main obstacles for full applicability of Open Access to biomedical resources is the researchers’ reluctance to make immediately and freely available these materials before having adequately exploited their potential. To analyse this issue from a wider perspective, we need to consider the role of research biobanks as main repositories in which human biological samples are stored, with or without accompanying them with genetic or clinical data (Haga and Beskow 2008). If withholding of biobanks’ resources drastically reduces their full value, their wide sharing is not simple to put into practice. The first and most complex barrier hindering Open Access is the lack of common standards, guidelines and legal frameworks due to socio-cultural differences of countries where biobanks operate (see Capocasa et al 2015 https://peerj.com/preprints/1212/). 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window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=20489645]").text(description); $(".js-view-count[data-work-id=20489645]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 20489645; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='20489645']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 20489645, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="15749984"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/15749984/Research_participants_perceptions_and_views_on_consent_for_biobank_research_a_review_of_empirical_data_and_ethical_analysis"><img alt="Research paper thumbnail of Research participants’ perceptions and views on consent for biobank research: a review of empirical data and ethical analysis" class="work-thumbnail" src="https://attachments.academia-assets.com/38811191/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/15749984/Research_participants_perceptions_and_views_on_consent_for_biobank_research_a_review_of_empirical_data_and_ethical_analysis">Research participants’ perceptions and views on consent for biobank research: a review of empirical data and ethical analysis</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background Appropriate information and consent has been one of the most intensely discussed topic...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background<br />Appropriate information and consent has been one of the most intensely discussed topics within the context of biobank research. In parallel to the normative debate, many socio-empirical studies have been conducted to gather experiences, preferences and views of patients, healthy research participants and further stakeholders. However, there is scarcity of literature which connects the normative debate about justifications for different consent models with findings gained in empirical research. In this paper we discuss findings of a limited review of socio-empirical research on patients’ and healthy research participants’ experiences and views regarding consent to biobank research in light of ethical principles for appropriate information and consent.<br /><br />Methods<br />Review question: Which empirical data are available on research participants’ perceptions and views regarding information and elicitation of consent for biobank research? Search of articles published till March 1st 2014 in Pubmed. Review of abstracts and potentially relevant full text articles by two authors independently. As categories for content analysis we defined (i) understanding or recall of information, (ii) preferences regarding information or consent, and (iii) research participants’ concerns.<br /><br />Results<br />The search in Pubmed yielded 337 abstracts of which 10 articles were included in this study. Approaches to information and consent varied considerably across the selected studies. The majority of research participants opted for some version of limited consent when being informed about such possibility. Among the factors influencing the type of preferred consent were information about sponsoring of biobank research by pharmaceutical industry and participants’ trade-off between privacy and perceived utility. Studies investigating research participants’ understanding and recall regarding the consent procedure indicated considerable lack of both aspects. Research participants’ perceptions of benefits and harms differ across those studies.<br /><br />Conclusion<br />The knowledge, perceptions and views of research participants who have undergone a consent procedure within the context of biobank research raise several questions on the issue of how to inform and elicit consent in an ethically acceptable way. In our empirical-ethical analysis we develop suggestions on how the practice of eliciting consent in the biobank context should be improved.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="350792280a305ca64675868ec331e851" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":38811191,"asset_id":15749984,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/38811191/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15749984"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15749984"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15749984; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15749984]").text(description); $(".js-view-count[data-work-id=15749984]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15749984; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15749984']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 15749984, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "350792280a305ca64675868ec331e851" } } $('.js-work-strip[data-work-id=15749984]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15749984,"title":"Research participants’ perceptions and views on consent for biobank research: a review of empirical data and ethical analysis","translated_title":"","metadata":{"abstract":"Background\nAppropriate information and consent has been one of the most intensely discussed topics within the context of biobank research. In parallel to the normative debate, many socio-empirical studies have been conducted to gather experiences, preferences and views of patients, healthy research participants and further stakeholders. However, there is scarcity of literature which connects the normative debate about justifications for different consent models with findings gained in empirical research. In this paper we discuss findings of a limited review of socio-empirical research on patients’ and healthy research participants’ experiences and views regarding consent to biobank research in light of ethical principles for appropriate information and consent.\n\nMethods\nReview question: Which empirical data are available on research participants’ perceptions and views regarding information and elicitation of consent for biobank research? Search of articles published till March 1st 2014 in Pubmed. Review of abstracts and potentially relevant full text articles by two authors independently. As categories for content analysis we defined (i) understanding or recall of information, (ii) preferences regarding information or consent, and (iii) research participants’ concerns.\n\nResults\nThe search in Pubmed yielded 337 abstracts of which 10 articles were included in this study. Approaches to information and consent varied considerably across the selected studies. The majority of research participants opted for some version of limited consent when being informed about such possibility. Among the factors influencing the type of preferred consent were information about sponsoring of biobank research by pharmaceutical industry and participants’ trade-off between privacy and perceived utility. Studies investigating research participants’ understanding and recall regarding the consent procedure indicated considerable lack of both aspects. Research participants’ perceptions of benefits and harms differ across those studies.\n\nConclusion\nThe knowledge, perceptions and views of research participants who have undergone a consent procedure within the context of biobank research raise several questions on the issue of how to inform and elicit consent in an ethically acceptable way. In our empirical-ethical analysis we develop suggestions on how the practice of eliciting consent in the biobank context should be improved.\n"},"translated_abstract":"Background\nAppropriate information and consent has been one of the most intensely discussed topics within the context of biobank research. In parallel to the normative debate, many socio-empirical studies have been conducted to gather experiences, preferences and views of patients, healthy research participants and further stakeholders. However, there is scarcity of literature which connects the normative debate about justifications for different consent models with findings gained in empirical research. In this paper we discuss findings of a limited review of socio-empirical research on patients’ and healthy research participants’ experiences and views regarding consent to biobank research in light of ethical principles for appropriate information and consent.\n\nMethods\nReview question: Which empirical data are available on research participants’ perceptions and views regarding information and elicitation of consent for biobank research? Search of articles published till March 1st 2014 in Pubmed. Review of abstracts and potentially relevant full text articles by two authors independently. As categories for content analysis we defined (i) understanding or recall of information, (ii) preferences regarding information or consent, and (iii) research participants’ concerns.\n\nResults\nThe search in Pubmed yielded 337 abstracts of which 10 articles were included in this study. Approaches to information and consent varied considerably across the selected studies. The majority of research participants opted for some version of limited consent when being informed about such possibility. Among the factors influencing the type of preferred consent were information about sponsoring of biobank research by pharmaceutical industry and participants’ trade-off between privacy and perceived utility. Studies investigating research participants’ understanding and recall regarding the consent procedure indicated considerable lack of both aspects. Research participants’ perceptions of benefits and harms differ across those studies.\n\nConclusion\nThe knowledge, perceptions and views of research participants who have undergone a consent procedure within the context of biobank research raise several questions on the issue of how to inform and elicit consent in an ethically acceptable way. 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Tra autonomia del paziente e medicina difensiva" class="work-thumbnail" src="https://attachments.academia-assets.com/37740189/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/12602852/Il_consenso_informato_in_ambito_terapeutico_Tra_autonomia_del_paziente_e_medicina_difensiva">Il consenso informato in ambito terapeutico. Tra autonomia del paziente e medicina difensiva</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">1. Breve storia del consenso informato Prime spinte verso il consenso informato La dichiarazione...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">1. Breve storia del consenso informato<br />Prime spinte verso il consenso informato <br />La dichiarazione di Helsinki<br />La convenzione di Oviedo<br />Il consenso informato nella regolamentazione italiana <br />Per riassumere <br /><br />2. Breve introduzione all’evoluzione bioetica del consenso informato<br />La medicina paternalistica e il principio di beneficità <br />Il principio di autodeterminazione, lo shared decision making, e l’empowerment del paziente<br />La trasparenza nel rapporto medico/paziente<br />Per riassumere <br /><br />3. Dal consenso informato alla decisione autonoma e informata<br />Il consenso informato tra efficacia terapeutica ed equità <br />Equità, giustizia sociale e medicina difensiva <br />Per riassumere <br /><br />Conclusioni <br /><br />Riferimenti Bibliografici</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="61534c7bcca97148459db4d144f883da" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37740189,"asset_id":12602852,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37740189/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="12602852"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="12602852"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12602852; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12602852]").text(description); $(".js-view-count[data-work-id=12602852]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12602852; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='12602852']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 12602852, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "61534c7bcca97148459db4d144f883da" } } $('.js-work-strip[data-work-id=12602852]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":12602852,"title":"Il consenso informato in ambito terapeutico. Tra autonomia del paziente e medicina difensiva","translated_title":"","metadata":{"abstract":"1. Breve storia del consenso informato\nPrime spinte verso il consenso informato \nLa dichiarazione di Helsinki\nLa convenzione di Oviedo\nIl consenso informato nella regolamentazione italiana \nPer riassumere \n\n2. Breve introduzione all’evoluzione bioetica del consenso informato\nLa medicina paternalistica e il principio di beneficità \nIl principio di autodeterminazione, lo shared decision making, e l’empowerment del paziente\nLa trasparenza nel rapporto medico/paziente\nPer riassumere \n\n3. Dal consenso informato alla decisione autonoma e informata\nIl consenso informato tra efficacia terapeutica ed equità \nEquità, giustizia sociale e medicina difensiva \nPer riassumere \n\nConclusioni \n\nRiferimenti Bibliografici "},"translated_abstract":"1. Breve storia del consenso informato\nPrime spinte verso il consenso informato \nLa dichiarazione di Helsinki\nLa convenzione di Oviedo\nIl consenso informato nella regolamentazione italiana \nPer riassumere \n\n2. Breve introduzione all’evoluzione bioetica del consenso informato\nLa medicina paternalistica e il principio di beneficità \nIl principio di autodeterminazione, lo shared decision making, e l’empowerment del paziente\nLa trasparenza nel rapporto medico/paziente\nPer riassumere \n\n3. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="10701225"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/10701225/Biobank_research_informed_consent_and_society_Towards_a_new_alliance"><img alt="Research paper thumbnail of Biobank research, informed consent and society. Towards a new alliance?" class="work-thumbnail" src="https://attachments.academia-assets.com/37290670/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/10701225/Biobank_research_informed_consent_and_society_Towards_a_new_alliance">Biobank research, informed consent and society. Towards a new alliance?</a></div><div class="wp-workCard_item"><span>Journal of Epidemiology and Community Health</span><span>, Feb 10, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">With the rise of -omics disciplines and biobank research, personal data and biosamples crossing n...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">With the rise of -omics disciplines and biobank research, personal data and biosamples crossing national borders pose new ethical questions. In this article, informed consent, as originally conceived, is shown as not being sufficient to address aims of research and interests of patients any more. Therefore the author has, after having scrutinised issues in biobanking, sketched a model of dynamic consent and a manner of scrutinising ethical issues through empirical data.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="993f626b7fc824c8c15ac13d6937f8a9" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37290670,"asset_id":10701225,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37290670/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="10701225"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="10701225"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 10701225; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=10701225]").text(description); $(".js-view-count[data-work-id=10701225]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 10701225; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='10701225']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 10701225, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "993f626b7fc824c8c15ac13d6937f8a9" } } $('.js-work-strip[data-work-id=10701225]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":10701225,"title":"Biobank research, informed consent and society. Towards a new alliance?","translated_title":"","metadata":{"abstract":"With the rise of -omics disciplines and biobank research, personal data and biosamples crossing national borders pose new ethical questions. In this article, informed consent, as originally conceived, is shown as not being sufficient to address aims of research and interests of patients any more. Therefore the author has, after having scrutinised issues in biobanking, sketched a model of dynamic consent and a manner of scrutinising ethical issues through empirical data.","publication_date":{"day":10,"month":2,"year":2015,"errors":{}},"publication_name":"Journal of Epidemiology and Community Health"},"translated_abstract":"With the rise of -omics disciplines and biobank research, personal data and biosamples crossing national borders pose new ethical questions. In this article, informed consent, as originally conceived, is shown as not being sufficient to address aims of research and interests of patients any more. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="1762036"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/1762036/Traslation_of_cancer_molecular_biomarkers_ethical_and_epistemological_issues"><img alt="Research paper thumbnail of Traslation of cancer molecular biomarkers ethical and epistemological issues" class="work-thumbnail" src="https://attachments.academia-assets.com/31941320/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/1762036/Traslation_of_cancer_molecular_biomarkers_ethical_and_epistemological_issues">Traslation of cancer molecular biomarkers ethical and epistemological issues</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The phenomenon of high cancer mortality has been the key factor in driving drug approval processe...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The phenomenon of high cancer mortality has been the key factor in driving drug approval processes and health-care policies. In this paper, we discuss the inconsistencies of the genetic model of cancer as applied in the case of colorectal cancer (CRC). The result of relying on a genetic model of CRC is the approval of cancer drugs based on the inhibition of the epidermal growth factor receptor. The poor clinical performance of these drugs has prompted the use of a molecular biomarker to find the respondent patients. Due to the complexity of the cancer cell biological pathways, even the use of a molecular biomarker has not improved the clinical response of treated patients. Within the clinical uncertainty derived from the limited predictive value of a cancer molecular biomarker, we analyse the patient-doctor relationship. Beyond the challenge of communicating the medical uncertainty, many influences coming from the health-care system make the medical decisions biased. We analyse the ethical justification in using drugs that, at best, extend the patients’ survival for a few weeks, then we proceed to highlight the excessive cost of these drugs that create a problem for the allocation of resources for the whole society. We hold that a sensitive evaluation before the use of costly drugs for metastatic cancers must enter into the physician-patient relationship balancing the ethical concerns of the oncologist community and the need for the development of preventive policies.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5e725e376c6caea151e631c86d8c559a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":31941320,"asset_id":1762036,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/31941320/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="1762036"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="1762036"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 1762036; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=1762036]").text(description); $(".js-view-count[data-work-id=1762036]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 1762036; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='1762036']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 1762036, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "5e725e376c6caea151e631c86d8c559a" } } $('.js-work-strip[data-work-id=1762036]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":1762036,"title":"Traslation of cancer molecular biomarkers ethical and epistemological issues","translated_title":"","metadata":{"abstract":"The phenomenon of high cancer mortality has been the key factor in driving drug approval processes and health-care policies. In this paper, we discuss the inconsistencies of the genetic model of cancer as applied in the case of colorectal cancer (CRC). The result of relying on a genetic model of CRC is the approval of cancer drugs based on the inhibition of the epidermal growth factor receptor. The poor clinical performance of these drugs has prompted the use of a molecular biomarker to find the respondent patients. Due to the complexity of the cancer cell biological pathways, even the use of a molecular biomarker has not improved the clinical response of treated patients. Within the clinical uncertainty derived from the limited predictive value of a cancer molecular biomarker, we analyse the patient-doctor relationship. Beyond the challenge of communicating the medical uncertainty, many influences coming from the health-care system make the medical decisions biased. We analyse the ethical justification in using drugs that, at best, extend the patients’ survival for a few weeks, then we proceed to highlight the excessive cost of these drugs that create a problem for the allocation of resources for the whole society. We hold that a sensitive evaluation before the use of costly drugs for metastatic cancers must enter into the physician-patient relationship balancing the ethical concerns of the oncologist community and the need for the development of preventive policies.","more_info":"pubblished on \"Human medical research\" 2011, Schildmann J., Sandow V., Rauprich O., Volmann J. (eds) Springer"},"translated_abstract":"The phenomenon of high cancer mortality has been the key factor in driving drug approval processes and health-care policies. In this paper, we discuss the inconsistencies of the genetic model of cancer as applied in the case of colorectal cancer (CRC). The result of relying on a genetic model of CRC is the approval of cancer drugs based on the inhibition of the epidermal growth factor receptor. The poor clinical performance of these drugs has prompted the use of a molecular biomarker to find the respondent patients. Due to the complexity of the cancer cell biological pathways, even the use of a molecular biomarker has not improved the clinical response of treated patients. Within the clinical uncertainty derived from the limited predictive value of a cancer molecular biomarker, we analyse the patient-doctor relationship. Beyond the challenge of communicating the medical uncertainty, many influences coming from the health-care system make the medical decisions biased. We analyse the ethical justification in using drugs that, at best, extend the patients’ survival for a few weeks, then we proceed to highlight the excessive cost of these drugs that create a problem for the allocation of resources for the whole society. We hold that a sensitive evaluation before the use of costly drugs for metastatic cancers must enter into the physician-patient relationship balancing the ethical concerns of the oncologist community and the need for the development of preventive policies.","internal_url":"https://www.academia.edu/1762036/Traslation_of_cancer_molecular_biomarkers_ethical_and_epistemological_issues","translated_internal_url":"","created_at":"2012-07-03T07:15:08.677-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":13342164,"work_id":1762036,"tagging_user_id":1231121,"tagged_user_id":46419085,"co_author_invite_id":3125305,"email":"c***i@iss.it","display_order":0,"name":"Cecilia Guastadisegni","title":"Traslation of cancer molecular biomarkers ethical and epistemological issues"}],"downloadable_attachments":[{"id":31941320,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/31941320/thumbnails/1.jpg","file_name":"HMR_14_DAbramo.pdf","download_url":"https://www.academia.edu/attachments/31941320/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Traslation_of_cancer_molecular_biomarker.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/31941320/HMR_14_DAbramo-libre.pdf?1391473124=\u0026response-content-disposition=attachment%3B+filename%3DTraslation_of_cancer_molecular_biomarker.pdf\u0026Expires=1732799330\u0026Signature=TF0DvBQF2l1QXZ5EOz8VjBcntzHJ8cKe0FkLhKK86T4I3HoSX5-QeLg50yfWaRj4aK7XSv5poAxpj2lsU2Bvlv5ASHum19AGeHdJX1WazwxXjdK0-KM3I915Kw2JamGMuMBmHnKzWYmh0a62NNDjK~aEW~XRIyNCtrDDzImA2cO5PkTfV~SeGexny0odffVmbMbdekvyTtA~biaDdRi6Li6VGSspNZW9cTN3ek0mzlnB4PP7yBvgDIblNVyQLpfNSV4NNY2BZcNGM6DrIUmZz7GUjaRotTVcxI283nDTr0V~fNCuz6TYXFxBbGkFMTWd6CKCJQkWN8mtufiq74oFdA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Traslation_of_cancer_molecular_biomarkers_ethical_and_epistemological_issues","translated_slug":"","page_count":22,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[{"id":31941320,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/31941320/thumbnails/1.jpg","file_name":"HMR_14_DAbramo.pdf","download_url":"https://www.academia.edu/attachments/31941320/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Traslation_of_cancer_molecular_biomarker.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/31941320/HMR_14_DAbramo-libre.pdf?1391473124=\u0026response-content-disposition=attachment%3B+filename%3DTraslation_of_cancer_molecular_biomarker.pdf\u0026Expires=1732799330\u0026Signature=TF0DvBQF2l1QXZ5EOz8VjBcntzHJ8cKe0FkLhKK86T4I3HoSX5-QeLg50yfWaRj4aK7XSv5poAxpj2lsU2Bvlv5ASHum19AGeHdJX1WazwxXjdK0-KM3I915Kw2JamGMuMBmHnKzWYmh0a62NNDjK~aEW~XRIyNCtrDDzImA2cO5PkTfV~SeGexny0odffVmbMbdekvyTtA~biaDdRi6Li6VGSspNZW9cTN3ek0mzlnB4PP7yBvgDIblNVyQLpfNSV4NNY2BZcNGM6DrIUmZz7GUjaRotTVcxI283nDTr0V~fNCuz6TYXFxBbGkFMTWd6CKCJQkWN8mtufiq74oFdA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":906,"name":"Applied Ethics","url":"https://www.academia.edu/Documents/in/Applied_Ethics"},{"id":4252,"name":"Computer Networks","url":"https://www.academia.edu/Documents/in/Computer_Networks"},{"id":9435,"name":"Medical Ethics","url":"https://www.academia.edu/Documents/in/Medical_Ethics"},{"id":27360,"name":"Databases","url":"https://www.academia.edu/Documents/in/Databases"},{"id":53293,"name":"Software","url":"https://www.academia.edu/Documents/in/Software"},{"id":1744493,"name":"Science and Technology Studies","url":"https://www.academia.edu/Documents/in/Science_and_Technology_Studies"}],"urls":[{"id":300424,"url":"http://www.springerlink.com/content/v6v7k2320082n338/"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="1765472"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/1765472/La_diversit%C3%A0_biologica_Analisi_epistemologica_della_relazione_tra_genetica_ed_epigenetica"><img alt="Research paper thumbnail of La diversità biologica. Analisi epistemologica della relazione tra genetica ed epigenetica." class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/1765472/La_diversit%C3%A0_biologica_Analisi_epistemologica_della_relazione_tra_genetica_ed_epigenetica">La diversità biologica. Analisi epistemologica della relazione tra genetica ed epigenetica.</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The first part of the thesis is a critical analysis of the proceedings of the conferences&amp;quo...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The first part of the thesis is a critical analysis of the proceedings of the conferences&amp;quot; Towards a Theoretical Biology&amp;quot; founded by the Rockefeller Foundation and leaded by Conrad H. Waddington. The second part is an epistemological and sociological analysis ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="1765472"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="1765472"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 1765472; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=1765472]").text(description); $(".js-view-count[data-work-id=1765472]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 1765472; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='1765472']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 1765472, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=1765472]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":1765472,"title":"La diversità biologica. 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If Johannsen’s genotype concept is a reprise of Woltereck’s Norm of Reaction, is also true that the former excluded the important role of environmental factors considered by the latter. Then, I describe some operational concepts taken from Woltereck’s Norm of Reaction and that through the work of Krafka and Hersch were transferred to Conrad Waddington in the contemporary biological debate. In the light of the role that epigenetics confers to the interaction between environmental factors and organisms’ development, the importance of the genetic code is questioned.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f1c6b525417bb48dd8812f740142774a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":36897035,"asset_id":11324606,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/36897035/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="11324606"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="11324606"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 11324606; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=11324606]").text(description); $(".js-view-count[data-work-id=11324606]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 11324606; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='11324606']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 11324606, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f1c6b525417bb48dd8812f740142774a" } } $('.js-work-strip[data-work-id=11324606]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":11324606,"title":"Some historical and epistemological remarks on genetics and epigenetics","translated_title":"","metadata":{"abstract":"In the article some remarks are made on the birth and development of genetics and epigenetics, and in respect of their relationship with environmental factors. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="184544" id="papers"><div class="js-work-strip profile--work_container" data-work-id="81543333"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/81543333/Biomolecular_Prospecting_Informative_Gaps_and_the_Cancer_Clinic_A_Qualitative_Fieldwork_and_an_Epistemological_Historical_and_Ethical_Analysis_of_Informed_Consent_for_Clinical_Trials_for_Monoclonal_Antibodies_and_Biobank_Research"><img alt="Research paper thumbnail of Biomolecular Prospecting, Informative Gaps, and the Cancer Clinic: A Qualitative Fieldwork and an Epistemological, Historical and Ethical Analysis of Informed Consent for Clinical Trials for Monoclonal Antibodies and Biobank Research" class="work-thumbnail" src="https://attachments.academia-assets.com/87869288/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/81543333/Biomolecular_Prospecting_Informative_Gaps_and_the_Cancer_Clinic_A_Qualitative_Fieldwork_and_an_Epistemological_Historical_and_Ethical_Analysis_of_Informed_Consent_for_Clinical_Trials_for_Monoclonal_Antibodies_and_Biobank_Research">Biomolecular Prospecting, Informative Gaps, and the Cancer Clinic: A Qualitative Fieldwork and an Epistemological, Historical and Ethical Analysis of Informed Consent for Clinical Trials for Monoclonal Antibodies and Biobank Research</a></div><div class="wp-workCard_item"><span>Frontiers in Genetics</span><span>, 2022</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">What happens to patients with cancer engaged in biomedical research when intellectual property re...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">What happens to patients with cancer engaged in biomedical research when intellectual property regimes and ethical regimes intersect? This qualitative historical study addresses this question by situating the experiences, hopes, and reasons of patients to enter clinical trials within the historical trajectory of informed consent and monoclonal antibodies, the biotechnology underpinning many targeted drugs used in oncological clinical trials and biobank research. Based on fieldwork we undertook in a German university hospital where we interviewed patients and the medical personnel, a historical review, and an ethical analysis we inquire into the effects that financial, legal, and technological changes connected to the relevant pharmaceutical research and commerce have on cancer patients engaged in clinical trials and biobank research. We find that the controversial aspects of monoclonal antibodies, especially those related to the commercial interests at stake, enter the informed consent process mainly in the form of informative gaps. We highlight how a qualitative analysis of the clinic, especially when it is situated against the backdrop of the history of related technological advancements and patent regime, it can serve the purpose of giving voice to subjects who are silenced by regimes of an ethical, epistemic, and commercial kind while pointing to informed consent as an unhelpful device for addressing risks arising from the commercial purposes of biomedical products and infrastructure.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c123a463cd24afdfa5f6459a08cdcb4c" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":87869288,"asset_id":81543333,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/87869288/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="81543333"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="81543333"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 81543333; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=81543333]").text(description); $(".js-view-count[data-work-id=81543333]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 81543333; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='81543333']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 81543333, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c123a463cd24afdfa5f6459a08cdcb4c" } } $('.js-work-strip[data-work-id=81543333]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":81543333,"title":"Biomolecular Prospecting, Informative Gaps, and the Cancer Clinic: A Qualitative Fieldwork and an Epistemological, Historical and Ethical Analysis of Informed Consent for Clinical Trials for Monoclonal Antibodies and Biobank Research","translated_title":"","metadata":{"doi":"10.3389/fgene.2022.872211","abstract":"What happens to patients with cancer engaged in biomedical research when intellectual property regimes and ethical regimes intersect? 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We highlight how a qualitative analysis of the clinic, especially when it is situated against the backdrop of the history of related technological advancements and patent regime, it can serve the purpose of giving voice to subjects who are silenced by regimes of an ethical, epistemic, and commercial kind while pointing to informed consent as an unhelpful device for addressing risks arising from the commercial purposes of biomedical products and infrastructure.","publication_date":{"day":null,"month":null,"year":2022,"errors":{}},"publication_name":"Frontiers in Genetics"},"translated_abstract":"What happens to patients with cancer engaged in biomedical research when intellectual property regimes and ethical regimes intersect? This qualitative historical study addresses this question by situating the experiences, hopes, and reasons of patients to enter clinical trials within the historical trajectory of informed consent and monoclonal antibodies, the biotechnology underpinning many targeted drugs used in oncological clinical trials and biobank research. Based on fieldwork we undertook in a German university hospital where we interviewed patients and the medical personnel, a historical review, and an ethical analysis we inquire into the effects that financial, legal, and technological changes connected to the relevant pharmaceutical research and commerce have on cancer patients engaged in clinical trials and biobank research. We find that the controversial aspects of monoclonal antibodies, especially those related to the commercial interests at stake, enter the informed consent process mainly in the form of informative gaps. We highlight how a qualitative analysis of the clinic, especially when it is situated against the backdrop of the history of related technological advancements and patent regime, it can serve the purpose of giving voice to subjects who are silenced by regimes of an ethical, epistemic, and commercial kind while pointing to informed consent as an unhelpful device for addressing risks arising from the commercial purposes of biomedical products and 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href="https://www.academia.edu/81542531/Targeted_drugs_and_Psycho_oncological_intervention_for_breast_cancer_patients"><img alt="Research paper thumbnail of Targeted drugs and Psycho-oncological intervention for breast cancer patients" class="work-thumbnail" src="https://attachments.academia-assets.com/87550401/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/81542531/Targeted_drugs_and_Psycho_oncological_intervention_for_breast_cancer_patients">Targeted drugs and Psycho-oncological intervention for breast cancer patients</a></div><div class="wp-workCard_item"><span>Journal of Negative Results in BioMedicine</span><span>, 2016</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="270c5ae61a7d204ca3ed97d7956ee6d4" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":87550401,"asset_id":81542531,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/87550401/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="81542531"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="81542531"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 81542531; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=81542531]").text(description); $(".js-view-count[data-work-id=81542531]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 81542531; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='81542531']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 81542531, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "270c5ae61a7d204ca3ed97d7956ee6d4" } } $('.js-work-strip[data-work-id=81542531]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":81542531,"title":"Targeted drugs and Psycho-oncological intervention for breast cancer patients","translated_title":"","metadata":{"publisher":"Springer Nature","grobid_abstract":"Personalized medicine is a new field based on molecular biology and genomics in which targeted tumor therapies are administered to patients. Psycho-oncology is a complementary approach that considers social and psychological aspects of patients as part of the treatments for cancer patients. The aim of this mini-review is to weigh clinical benefits for breast cancer patients of both treatments and possibily enhance benefits by modulating the use of both interventions. We have compared and evaluated on the one hand the use of anti Vascular Endothelial Growth Factor and, on the other hand, psycho-oncological interventions in metastatic and non-metastatic breast cancer patients. Both treatments did not increase survival of metastatic breast cancer patients, while in a selected study psychooncological interventions extended lifespan of non-metastatic breast cancer patients and ameliorate psychological and social factors of metastatic breast cancer patients. Because the two approaches address completely different aspects of cancer patients, if the comparison is limited to the extension of survival, the value of these two treatments cannot be assessed and compared. It is likely that by comparing patients reported outcomes, possibly by using standardized Quality of Life questionnaires, both patients and health care providers can weigh the benefits of the two treatments. 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data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/55850941/Political_Epistemology_of_Pandemic_Management"><img alt="Research paper thumbnail of Political Epistemology of Pandemic Management" class="work-thumbnail" src="https://attachments.academia-assets.com/71524581/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/55850941/Political_Epistemology_of_Pandemic_Management">Political Epistemology of Pandemic Management</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unive.academia.edu/GiuliaGandolfi">Giulia Gandolfi</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Today, claims about the contiguity of health management and societal organization bring biopoliti...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Today, claims about the contiguity of health management and societal organization bring biopolitical concerns to the forefront. This essay offers historical-political insights on the covid-19 pandemic, which are particularly urgent, as both the temporal and the cultural-political dimensions have been insufficiently considered in current debates. After introducing our specific political-epistemological approach, we delve into the entanglements of medical expertise, economic interests, surveillance politics, and diplomatic relations in the past in order to shed light on the present. Additionally, we address the limitations of Italian theory's biopolitica, namely its idle radicalization of critical views on medical politics inspired by French épistémologie historique. We conclude with a call to scientists' responsibility in consideration of the societal embedment of their activity. Yet, the task of an emancipated science is not only in their hands but depends on our collective capacity to organically connect their work to the renewal of the body politics at large.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8d9ba6d1aa19ef004d7b7e7d5bf1c281" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":71524581,"asset_id":55850941,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/71524581/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="55850941"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="55850941"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 55850941; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=55850941]").text(description); $(".js-view-count[data-work-id=55850941]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 55850941; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='55850941']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 55850941, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8d9ba6d1aa19ef004d7b7e7d5bf1c281" } } $('.js-work-strip[data-work-id=55850941]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":55850941,"title":"Political Epistemology of Pandemic Management","translated_title":"","metadata":{"abstract":"Today, claims about the contiguity of health management and societal organization bring biopolitical concerns to the forefront. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="50276823"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/50276823/Antibiotic_resistance_planetary_health_and_the_mimetic_trap_A_historical_account_of_present_day_sanitary_environmental_and_social_crises"><img alt="Research paper thumbnail of Antibiotic resistance, planetary health and the mimetic trap: A historical account of present-day sanitary, environmental and social crises" class="work-thumbnail" src="https://attachments.academia-assets.com/68829519/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/50276823/Antibiotic_resistance_planetary_health_and_the_mimetic_trap_A_historical_account_of_present_day_sanitary_environmental_and_social_crises">Antibiotic resistance, planetary health and the mimetic trap: A historical account of present-day sanitary, environmental and social crises</a></div><div class="wp-workCard_item"><span>Postcolonial Studies</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The industrialisation of food production over the past century has triggered a series of sanitary...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The industrialisation of food production over the past century has triggered a series of sanitary crises related to antibiotic resistance. In this article, I contend that to understand the radical transformation of animal farming and its effects on public health, we need to inquire into the historical development of the knowledge on microbes, especially with regard to the agricultural industry’s mobilisation and repression of microbial metabolism to scale up food production. Moreover, I conceive of the so-called Great Acceleration of the Anthropocene as a postcolonial mimetic trap through which actors who didn’t play an active role in the contemporary ecological collapse are subsumed into an indistinct “we”. To disentangle this alleged collective subject created from accounts of planetary health, I focus on the scientific, social, and institutional histories of antibiotic production and antibiotic use that materialised in the epidemiological issue of antibiotic resistance. Furthermore, I highlight how the history of antibiotic use and resistance is intertwined with the ecological, social, and geopolitical dynamics created by intense industrial production and international rivalries during the Cold War. This article calls for the re-evaluation and creation of counter-narratives of the planetary impact of industry on microbes, local communities, patients, medical personnel, and the global poor.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="81fc811ae8301cfa5679bfdef5b6491e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":68829519,"asset_id":50276823,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/68829519/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="50276823"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="50276823"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 50276823; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=50276823]").text(description); $(".js-view-count[data-work-id=50276823]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 50276823; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='50276823']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 50276823, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "81fc811ae8301cfa5679bfdef5b6491e" } } $('.js-work-strip[data-work-id=50276823]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":50276823,"title":"Antibiotic resistance, planetary health and the mimetic trap: A historical account of present-day sanitary, environmental and social crises","translated_title":"","metadata":{"doi":"10.1080/13688790.2021.1963093","abstract":"The industrialisation of food production over the past century has triggered a series of sanitary crises related to antibiotic resistance. In this article, I contend that to understand the radical transformation of animal farming and its effects on public health, we need to inquire into the historical development of the knowledge on microbes, especially with regard to the agricultural industry’s mobilisation and repression of microbial metabolism to scale up food production. Moreover, I conceive of the so-called Great Acceleration of the Anthropocene as a postcolonial mimetic trap through which actors who didn’t play an active role in the contemporary ecological collapse are subsumed into an indistinct “we”. To disentangle this alleged collective subject created from accounts of planetary health, I focus on the scientific, social, and institutional histories of antibiotic production and antibiotic use that materialised in the epidemiological issue of antibiotic resistance. Furthermore, I highlight how the history of antibiotic use and resistance is intertwined with the ecological, social, and geopolitical dynamics created by intense industrial production and international rivalries during the Cold War. This article calls for the re-evaluation and creation of counter-narratives of the planetary impact of industry on microbes, local communities, patients, medical personnel, and the global poor.","publication_date":{"day":null,"month":null,"year":2021,"errors":{}},"publication_name":"Postcolonial Studies"},"translated_abstract":"The industrialisation of food production over the past century has triggered a series of sanitary crises related to antibiotic resistance. 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Furthermore, I highlight how the history of antibiotic use and resistance is intertwined with the ecological, social, and geopolitical dynamics created by intense industrial production and international rivalries during the Cold War. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="49025352"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/49025352/The_past_and_present_of_pandemic_management_health_diplomacy_international_epidemiological_surveillance_and_COVID_19"><img alt="Research paper thumbnail of The past and present of pandemic management: health diplomacy, international epidemiological surveillance, and COVID‑19" class="work-thumbnail" src="https://attachments.academia-assets.com/67410154/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/49025352/The_past_and_present_of_pandemic_management_health_diplomacy_international_epidemiological_surveillance_and_COVID_19">The past and present of pandemic management: health diplomacy, international epidemiological surveillance, and COVID‑19</a></div><div class="wp-workCard_item"><span>History and Philosophy of the Life Sciences</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The establishment of international sanitary institutions, which took place in the context of riva...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The establishment of international sanitary institutions, which took place in the context of rivalry among the great European powers and their colonial expan-sion in Asia, allowed for the development of administrative systems of international epidemiological surveillance as a response to the cholera epidemics at the end of the nineteenth century. In this note, I reflect on how a historical analysis of the inception of international epidemiological surveillance and pandemic management helps us to understand what is happening in the COVID-19 pandemic today.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="12c2c9adbbc017d5f0433cdced5cbc47" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":67410154,"asset_id":49025352,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/67410154/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="49025352"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="49025352"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 49025352; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=49025352]").text(description); $(".js-view-count[data-work-id=49025352]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 49025352; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='49025352']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 49025352, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "12c2c9adbbc017d5f0433cdced5cbc47" } } $('.js-work-strip[data-work-id=49025352]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":49025352,"title":"The past and present of pandemic management: health diplomacy, international epidemiological surveillance, and COVID‑19","translated_title":"","metadata":{"doi":"10.1007/s40656-021-00416-4","abstract":"The establishment of international sanitary institutions, which took place in the context of rivalry among the great European powers and their colonial expan-sion in Asia, allowed for the development of administrative systems of international epidemiological surveillance as a response to the cholera epidemics at the end of the nineteenth century. In this note, I reflect on how a historical analysis of the inception of international epidemiological surveillance and pandemic management helps us to understand what is happening in the COVID-19 pandemic today.","publication_date":{"day":null,"month":null,"year":2021,"errors":{}},"publication_name":"History and Philosophy of the Life Sciences"},"translated_abstract":"The establishment of international sanitary institutions, which took place in the context of rivalry among the great European powers and their colonial expan-sion in Asia, allowed for the development of administrative systems of international epidemiological surveillance as a response to the cholera epidemics at the end of the nineteenth century. In this note, I reflect on how a historical analysis of the inception of international epidemiological surveillance and pandemic management helps us to understand what is happening in the COVID-19 pandemic today.","internal_url":"https://www.academia.edu/49025352/The_past_and_present_of_pandemic_management_health_diplomacy_international_epidemiological_surveillance_and_COVID_19","translated_internal_url":"","created_at":"2021-05-23T13:11:06.588-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":67410154,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/67410154/thumbnails/1.jpg","file_name":"s40656-021-00416-4.pdf","download_url":"https://www.academia.edu/attachments/67410154/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"The_past_and_present_of_pandemic_managem.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/67410154/s40656-021-00416-4-libre.pdf?1621802106=\u0026response-content-disposition=attachment%3B+filename%3DThe_past_and_present_of_pandemic_managem.pdf\u0026Expires=1732799329\u0026Signature=IxcByzNn8a2jktuRT2JuC1ZDXdrNDE3eUXg-1hBBcC5cWPPJM63mHGPyoVcDSemxOopElnMWcvv7Q0YcAnwRA9I-wun0eqyIHNa43qa-AOHFu0EVEfwdJocye~fxVX8h~i8UlY7ZLvjQAPIOabmq7RuRHk0nn0yWW2686~3RJL42VzgGtWkSwOSPnA1eEvNu9UcFJYeHpbHD9eiZkS-GVbLK-sAb4ZMrSOdGSI1xNDff7UFO4Xh7jl2vZWfgHQaKWQWUDZ2q0XYyZ6eHjJXcAUgs6MGSvVRtu87~qLj9wV1OWpugivtu5BxVcsrCINO36KweyfKhToHfPiDJl79mmw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"The_past_and_present_of_pandemic_management_health_diplomacy_international_epidemiological_surveillance_and_COVID_19","translated_slug":"","page_count":6,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[{"id":67410154,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/67410154/thumbnails/1.jpg","file_name":"s40656-021-00416-4.pdf","download_url":"https://www.academia.edu/attachments/67410154/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"The_past_and_present_of_pandemic_managem.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/67410154/s40656-021-00416-4-libre.pdf?1621802106=\u0026response-content-disposition=attachment%3B+filename%3DThe_past_and_present_of_pandemic_managem.pdf\u0026Expires=1732799329\u0026Signature=IxcByzNn8a2jktuRT2JuC1ZDXdrNDE3eUXg-1hBBcC5cWPPJM63mHGPyoVcDSemxOopElnMWcvv7Q0YcAnwRA9I-wun0eqyIHNa43qa-AOHFu0EVEfwdJocye~fxVX8h~i8UlY7ZLvjQAPIOabmq7RuRHk0nn0yWW2686~3RJL42VzgGtWkSwOSPnA1eEvNu9UcFJYeHpbHD9eiZkS-GVbLK-sAb4ZMrSOdGSI1xNDff7UFO4Xh7jl2vZWfgHQaKWQWUDZ2q0XYyZ6eHjJXcAUgs6MGSvVRtu87~qLj9wV1OWpugivtu5BxVcsrCINO36KweyfKhToHfPiDJl79mmw__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":2273,"name":"History of Medicine","url":"https://www.academia.edu/Documents/in/History_of_Medicine"},{"id":3723,"name":"History of Science","url":"https://www.academia.edu/Documents/in/History_of_Science"},{"id":6556,"name":"Colonialism","url":"https://www.academia.edu/Documents/in/Colonialism"},{"id":16302,"name":"History Of Disease","url":"https://www.academia.edu/Documents/in/History_Of_Disease"},{"id":28969,"name":"History and philosophy of science (History)","url":"https://www.academia.edu/Documents/in/History_and_philosophy_of_science_History_"},{"id":33351,"name":"History of Epidemiology","url":"https://www.academia.edu/Documents/in/History_of_Epidemiology"},{"id":108521,"name":"Global Health Diplomacy","url":"https://www.academia.edu/Documents/in/Global_Health_Diplomacy"},{"id":666038,"name":"History of Colonialism","url":"https://www.academia.edu/Documents/in/History_of_Colonialism"}],"urls":[{"id":10217574,"url":"https://link.springer.com/content/pdf/10.1007/s40656-021-00416-4.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="43652254"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/43652254/A_Historical_and_Political_Epistemology_of_Microbes"><img alt="Research paper thumbnail of A Historical and Political Epistemology of Microbes" class="work-thumbnail" src="https://attachments.academia-assets.com/63977964/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/43652254/A_Historical_and_Political_Epistemology_of_Microbes">A Historical and Political Epistemology of Microbes</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/SybilleNeumeyer">Sybille Neumeyer</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a></span></div><div class="wp-workCard_item"><span>Centaurus</span><span>, 2020</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">This article traces the historical co-evolution of microbiology, bacteriology, and virology, fram...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">This article traces the historical co-evolution of microbiology, bacteriology, and virology, framed within industrial and agricultural contexts, as well as their role in colonial and national history between the end of the 19th century and the first decades of the 20th century. The epistemology of germ theory, coupled with the economic interests of European colonies, has shaped the understanding of human-microbial relationships in a reductionist way. We explore a brief history of the medical and biological sciences, focusing on microbes and the difficulty of implementing germ theory outside of biology laboratories. Furthermore, we highlight the work of Lynn Margulis, who conceptualized microbes within their ecological contexts. Such research shows the active role microbes play in handling life-sustaining biological and biochemical processes. We outline how the industrial and technological advancements of the last two centuries not only impacted almost all human societies, but also changed the world on microbial, biological, and geological levels. The narration of these histories is a complex task, and depends on how national, international, and intergovernmental institutions (such as the World Health Organization) conceive of the selective environmental pressures exerted by industry and biotechnological companies.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c4cc213175fec2020eab1f2bbe57c7d7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":63977964,"asset_id":43652254,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/63977964/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="43652254"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="43652254"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 43652254; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=43652254]").text(description); $(".js-view-count[data-work-id=43652254]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 43652254; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='43652254']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 43652254, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c4cc213175fec2020eab1f2bbe57c7d7" } } $('.js-work-strip[data-work-id=43652254]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":43652254,"title":"A Historical and Political Epistemology of Microbes","translated_title":"","metadata":{"doi":"10.1111/1600-0498.12300","volume":"62","abstract":"This article traces the historical co-evolution of microbiology, bacteriology, and virology, framed within industrial and agricultural contexts, as well as their role in colonial and national history between the end of the 19th century and the first decades of the 20th century. The epistemology of germ theory, coupled with the economic interests of European colonies, has shaped the understanding of human-microbial relationships in a reductionist way. We explore a brief history of the medical and biological sciences, focusing on microbes and the difficulty of implementing germ theory outside of biology laboratories. Furthermore, we highlight the work of Lynn Margulis, who conceptualized microbes within their ecological contexts. Such research shows the active role microbes play in handling life-sustaining biological and biochemical processes. We outline how the industrial and technological advancements of the last two centuries not only impacted almost all human societies, but also changed the world on microbial, biological, and geological levels. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="39769580"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/39769580/Anthropocene_in_the_cell"><img alt="Research paper thumbnail of Anthropocene in the cell" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/39769580/Anthropocene_in_the_cell">Anthropocene in the cell</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://ucla.academia.edu/HannahLandecker">Hannah Landecker</a></span></div><div class="wp-workCard_item"><span>Technosphere Magazine, Dossier # Substances</span><span>, 2019</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">What does it take for the life sciences to reflect on themselves and their conceptual models in t...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">What does it take for the life sciences to reflect on themselves and their conceptual models in the era of the technosphere? In this conversation, sociologist Hannah Landecker and historian of science Flavio D’Abramo discuss the drastic shifts in our understandings of body-environment dynamics made visible by recent insights within the fields of epidemiology and epigenetics. They point to the necessity of reflecting on the limits of the organism itself, given the ways in which the social, ecological, and multi-species environments are intertwined with the biological one.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="39769580"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="39769580"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 39769580; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=39769580]").text(description); $(".js-view-count[data-work-id=39769580]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 39769580; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='39769580']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 39769580, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=39769580]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":39769580,"title":"Anthropocene in the cell","translated_title":"","metadata":{"abstract":"What does it take for the life sciences to reflect on themselves and their conceptual models in the era of the technosphere? In this conversation, sociologist Hannah Landecker and historian of science Flavio D’Abramo discuss the drastic shifts in our understandings of body-environment dynamics made visible by recent insights within the fields of epidemiology and epigenetics. They point to the necessity of reflecting on the limits of the organism itself, given the ways in which the social, ecological, and multi-species environments are intertwined with the biological one.","publication_date":{"day":null,"month":null,"year":2019,"errors":{}},"publication_name":"Technosphere Magazine, Dossier # Substances"},"translated_abstract":"What does it take for the life sciences to reflect on themselves and their conceptual models in the era of the technosphere? In this conversation, sociologist Hannah Landecker and historian of science Flavio D’Abramo discuss the drastic shifts in our understandings of body-environment dynamics made visible by recent insights within the fields of epidemiology and epigenetics. They point to the necessity of reflecting on the limits of the organism itself, given the ways in which the social, ecological, and multi-species environments are intertwined with the biological one.","internal_url":"https://www.academia.edu/39769580/Anthropocene_in_the_cell","translated_internal_url":"","created_at":"2019-07-07T14:01:47.802-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":32794138,"work_id":39769580,"tagging_user_id":1231121,"tagged_user_id":31304507,"co_author_invite_id":null,"email":"l***r@soc.ucla.edu","affiliation":"University of California, Los Angeles","display_order":0,"name":"Hannah Landecker","title":"Anthropocene in the cell"}],"downloadable_attachments":[],"slug":"Anthropocene_in_the_cell","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[],"research_interests":[{"id":823,"name":"Philosophy of Biology","url":"https://www.academia.edu/Documents/in/Philosophy_of_Biology"},{"id":1083,"name":"Developmental Biology","url":"https://www.academia.edu/Documents/in/Developmental_Biology"},{"id":1085,"name":"Epidemiology","url":"https://www.academia.edu/Documents/in/Epidemiology"},{"id":1512,"name":"Climate Change","url":"https://www.academia.edu/Documents/in/Climate_Change"},{"id":3407,"name":"Environmental Studies","url":"https://www.academia.edu/Documents/in/Environmental_Studies"},{"id":7076,"name":"Taxonomy","url":"https://www.academia.edu/Documents/in/Taxonomy"},{"id":9846,"name":"Ecology","url":"https://www.academia.edu/Documents/in/Ecology"},{"id":13075,"name":"History of Biology","url":"https://www.academia.edu/Documents/in/History_of_Biology"},{"id":16288,"name":"Public Health","url":"https://www.academia.edu/Documents/in/Public_Health"},{"id":22404,"name":"Epigenetics","url":"https://www.academia.edu/Documents/in/Epigenetics"},{"id":26898,"name":"Ecological Developmental Biology","url":"https://www.academia.edu/Documents/in/Ecological_Developmental_Biology"},{"id":35620,"name":"Antibiotic Resistance","url":"https://www.academia.edu/Documents/in/Antibiotic_Resistance"},{"id":39738,"name":"Anthropocene studies","url":"https://www.academia.edu/Documents/in/Anthropocene_studies"},{"id":53944,"name":"Gut Microbiome","url":"https://www.academia.edu/Documents/in/Gut_Microbiome"},{"id":53948,"name":"Human Microbiome","url":"https://www.academia.edu/Documents/in/Human_Microbiome"},{"id":149474,"name":"Anthropocene","url":"https://www.academia.edu/Documents/in/Anthropocene"},{"id":781620,"name":"Culture and the Anthropocene","url":"https://www.academia.edu/Documents/in/Culture_and_the_Anthropocene"}],"urls":[{"id":8826671,"url":"https://technosphere-magazine.hkw.de/p/Anthropocene-in-the-Cell-fQjoLLgrE7jbXzLYr1TLNn"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="36805309"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/36805309/The_bench_is_closer_to_the_bedside_than_we_think_Uncovering_the_ethical_ties_between_preclinical_researchers_in_translational_neuroscience_and_patients_in_clinical_trials"><img alt="Research paper thumbnail of The bench is closer to the bedside than we think: Uncovering the ethical ties between preclinical researchers in translational neuroscience and patients in clinical trials" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/36805309/The_bench_is_closer_to_the_bedside_than_we_think_Uncovering_the_ethical_ties_between_preclinical_researchers_in_translational_neuroscience_and_patients_in_clinical_trials">The bench is closer to the bedside than we think: Uncovering the ethical ties between preclinical researchers in translational neuroscience and patients in clinical trials</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Millions of people worldwide currently suffer from serious neurological diseases and injuries for...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Millions of people worldwide currently suffer from serious neurological diseases and injuries for which there are few, and often no, effective treatments. The paucity of effective interventions is, no doubt, due in large part to the complexity of the disorders, as well as our currently limited understanding of their pathophysiology. The bleak picture for patients, however, is also attributable to avoidable impediments stemming from quality concerns in preclinical research that often escape detection by research regulation efforts. In our essay, we connect the dots between these concerns about the quality of preclinical research and their potential ethical impact on the patients who volunteer for early trials of interventions informed by it. We do so in hopes that a greater appreciation among preclinical researchers of these serious ethical consequences can lead to a greater commitment within the research community to adopt widely available tools and measures that can help to improve the quality of research.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="36805309"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="36805309"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 36805309; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=36805309]").text(description); $(".js-view-count[data-work-id=36805309]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 36805309; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='36805309']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 36805309, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=36805309]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":36805309,"title":"The bench is closer to the bedside than we think: Uncovering the ethical ties between preclinical researchers in translational neuroscience and patients in clinical trials","translated_title":"","metadata":{"abstract":"Millions of people worldwide currently suffer from serious neurological diseases and injuries for which there are few, and often no, effective treatments. The paucity of effective interventions is, no doubt, due in large part to the complexity of the disorders, as well as our currently limited understanding of their pathophysiology. The bleak picture for patients, however, is also attributable to avoidable impediments stemming from quality concerns in preclinical research that often escape detection by research regulation efforts. In our essay, we connect the dots between these concerns about the quality of preclinical research and their potential ethical impact on the patients who volunteer for early trials of interventions informed by it. We do so in hopes that a greater appreciation among preclinical researchers of these serious ethical consequences can lead to a greater commitment within the research community to adopt widely available tools and measures that can help to improve the quality of research."},"translated_abstract":"Millions of people worldwide currently suffer from serious neurological diseases and injuries for which there are few, and often no, effective treatments. The paucity of effective interventions is, no doubt, due in large part to the complexity of the disorders, as well as our currently limited understanding of their pathophysiology. The bleak picture for patients, however, is also attributable to avoidable impediments stemming from quality concerns in preclinical research that often escape detection by research regulation efforts. In our essay, we connect the dots between these concerns about the quality of preclinical research and their potential ethical impact on the patients who volunteer for early trials of interventions informed by it. We do so in hopes that a greater appreciation among preclinical researchers of these serious ethical consequences can lead to a greater commitment within the research community to adopt widely available tools and measures that can help to improve the quality of research.","internal_url":"https://www.academia.edu/36805309/The_bench_is_closer_to_the_bedside_than_we_think_Uncovering_the_ethical_ties_between_preclinical_researchers_in_translational_neuroscience_and_patients_in_clinical_trials","translated_internal_url":"","created_at":"2018-06-08T03:03:10.703-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_bench_is_closer_to_the_bedside_than_we_think_Uncovering_the_ethical_ties_between_preclinical_researchers_in_translational_neuroscience_and_patients_in_clinical_trials","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[],"research_interests":[{"id":9435,"name":"Medical Ethics","url":"https://www.academia.edu/Documents/in/Medical_Ethics"},{"id":608787,"name":"Ethics in Scientific Publication","url":"https://www.academia.edu/Documents/in/Ethics_in_Scientific_Publication"}],"urls":[{"id":8516907,"url":"http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2006343\u0026utm_source=feedburner\u0026utm_medium=feed\u0026utm_campaign=Feed:+plosbiology/NewArticles+(PLOS+Biology+-+New+Articles)"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="33940317"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/33940317/Health_wealth_and_behavioural_change_an_exploration_of_role_responsibilities_in_the_wake_of_epigenetics"><img alt="Research paper thumbnail of Health, wealth and behavioural change: an exploration of role responsibilities in the wake of epigenetics" class="work-thumbnail" src="https://attachments.academia-assets.com/53972427/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/33940317/Health_wealth_and_behavioural_change_an_exploration_of_role_responsibilities_in_the_wake_of_epigenetics">Health, wealth and behavioural change: an exploration of role responsibilities in the wake of epigenetics</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/DanyaFVears">Danya F. Vears</a></span></div><div class="wp-workCard_item"><span>Journal of Community Genetics</span><span>, 2017</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The field of epigenetics is leading to new conceptualizations of the role of environmental factor...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The field of epigenetics is leading to new conceptualizations of the role of environmental factors in health and genetic disease. Although more evidence is required, epigenetic mechanisms are being implicated in the link between low socioeconomic status and poor health status. Epigenetic phenomena work in a number of ways: they can be established early in development, transmitted from previous generations and/or responsive to environmental factors. Knowledge about these types of epigenetic traits might therefore allow us to move away from a genetic deterministic perspective, and provide individuals with the opportunity to change their health status. Although this could be equated with patient empowerment, it could also lead to stigmatization and discrimination where individuals are deemed responsible for their health, even if they are not in social situations where they are able to enact change that would alter their health status. In this paper, we will explore the responsibilities of different actors in the healthcare sphere in relation to epigenetics across four different contexts: (1) genetic research, (2) clinical practice, (3) prenatal care and (4) the workplace. Within this exploration of role responsibilities, we will also discuss the potential constraints that might prevent the patient, mother-to-be, research participant or employee, from enacting any necessary steps in order to increase their health status in response to epigenetic information.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="04698566bdf57d993925248cd1477537" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":53972427,"asset_id":33940317,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/53972427/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="33940317"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="33940317"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33940317; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33940317]").text(description); $(".js-view-count[data-work-id=33940317]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33940317; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='33940317']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 33940317, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "04698566bdf57d993925248cd1477537" } } $('.js-work-strip[data-work-id=33940317]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":33940317,"title":"Health, wealth and behavioural change: an exploration of role responsibilities in the wake of epigenetics","translated_title":"","metadata":{"doi":"10.1007/s12687-017-0315-7","abstract":"The field of epigenetics is leading to new conceptualizations of the role of environmental factors in health and genetic disease. 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In this paper, we will explore the responsibilities of different actors in the healthcare sphere in relation to epigenetics across four different contexts: (1) genetic research, (2) clinical practice, (3) prenatal care and (4) the workplace. Within this exploration of role responsibilities, we will also discuss the potential constraints that might prevent the patient, mother-to-be, research participant or employee, from enacting any necessary steps in order to increase their health status in response to epigenetic information.","page_numbers":"1-15","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"Journal of Community Genetics"},"translated_abstract":"The field of epigenetics is leading to new conceptualizations of the role of environmental factors in health and genetic disease. Although more evidence is required, epigenetic mechanisms are being implicated in the link between low socioeconomic status and poor health status. Epigenetic phenomena work in a number of ways: they can be established early in development, transmitted from previous generations and/or responsive to environmental factors. Knowledge about these types of epigenetic traits might therefore allow us to move away from a genetic deterministic perspective, and provide individuals with the opportunity to change their health status. Although this could be equated with patient empowerment, it could also lead to stigmatization and discrimination where individuals are deemed responsible for their health, even if they are not in social situations where they are able to enact change that would alter their health status. In this paper, we will explore the responsibilities of different actors in the healthcare sphere in relation to epigenetics across four different contexts: (1) genetic research, (2) clinical practice, (3) prenatal care and (4) the workplace. Within this exploration of role responsibilities, we will also discuss the potential constraints that might prevent the patient, mother-to-be, research participant or employee, from enacting any necessary steps in order to increase their health status in response to epigenetic information.","internal_url":"https://www.academia.edu/33940317/Health_wealth_and_behavioural_change_an_exploration_of_role_responsibilities_in_the_wake_of_epigenetics","translated_internal_url":"","created_at":"2017-07-19T07:21:48.217-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":29766953,"work_id":33940317,"tagging_user_id":1231121,"tagged_user_id":66579001,"co_author_invite_id":6437366,"email":"d***s@kuleuven.be","display_order":0,"name":"Danya F. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="23943968"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/23943968/Targeted_drugs_and_Psycho_oncological_intervention_for_breast_cancer_patients"><img alt="Research paper thumbnail of Targeted drugs and Psycho-oncological intervention for breast cancer patients" class="work-thumbnail" src="https://attachments.academia-assets.com/44328973/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/23943968/Targeted_drugs_and_Psycho_oncological_intervention_for_breast_cancer_patients">Targeted drugs and Psycho-oncological intervention for breast cancer patients</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/CeciliaGuastadisegni">Cecilia Guastadisegni</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://independent.academia.edu/UteGoerling">Ute Goerling</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Personalized medicine is a new field based on molecular biology and genomics in which targeted tu...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Personalized medicine is a new field based on molecular biology and genomics in which targeted tumor therapies are administered to patients. Psycho-oncology is a complementary approach that considers social and psychological aspects of patients as part of the treatments for cancer patients.<br /><br />The aim of this mini-review is to weigh clinical benefits for breast cancer patients of both treatments and possibily enhance benefits by modulating the use of both interventions. We have compared and evaluated on the one hand the use of anti Vascular Endothelial Growth Factor and, on the other hand, psycho-oncological interventions in metastatic and non-metastatic breast cancer patients.<br /><br />Both treatments did not increase survival of metastatic breast cancer patients, while in a selected study psycho-oncological interventions extended lifespan of non-metastatic breast cancer patients and ameliorate psychological and social factors of metastatic breast cancer patients. Because the two approaches address completely different aspects of cancer patients, if the comparison is limited to the extension of survival, the value of these two treatments cannot be assessed and compared.<br /><br />It is likely that by comparing patients reported outcomes, possibly by using standardized Quality of Life questionnaires, both patients and health care providers can weigh the benefits of the two treatments. It is therefore important to evaluate the use of cancer patients’ quality of life measures as a mean to improve their experiences about life and treatment, and possibly to extend their survival.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="c381eb22b0837e05f4686bb9b4ff405e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":44328973,"asset_id":23943968,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/44328973/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="23943968"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="23943968"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 23943968; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=23943968]").text(description); $(".js-view-count[data-work-id=23943968]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 23943968; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='23943968']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 23943968, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "c381eb22b0837e05f4686bb9b4ff405e" } } $('.js-work-strip[data-work-id=23943968]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":23943968,"title":"Targeted drugs and Psycho-oncological intervention for breast cancer patients","translated_title":"","metadata":{"abstract":"Personalized medicine is a new field based on molecular biology and genomics in which targeted tumor therapies are administered to patients. 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class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/22552525/Samples_and_data_accessibility_in_research_biobanks_an_explorative_survey"><img alt="Research paper thumbnail of Samples and data accessibility in research biobanks: an explorative survey" class="work-thumbnail" src="https://attachments.academia-assets.com/43165905/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/22552525/Samples_and_data_accessibility_in_research_biobanks_an_explorative_survey">Samples and data accessibility in research biobanks: an explorative survey</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Biobanks, which contain human biological samples and/or data, provide a crucial contribution to t...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Biobanks, which contain human biological samples and/or data, provide a crucial contribution to the progress of biomedical research. However, the effective and efficient use of biobank resources depends on their accessibility. In fact, making bio-resources promptly accessible to everybody may increase the benefits for society. Furthermore, optimizing their use and ensuring their quality will promote scientific creativity and, in general, contribute to the progress of bio-medical research. Although this has become a rather common belief, several laboratories are still secretive and continue to withhold samples and data. In this study, we conducted a questionnaire-<br />based survey in order to investigate sample and data accessibility in research biobanks operating all over the world. The survey involved a total of 46 biobanks. Most of them gave permission to access their samples (95.7%) and data (85.4%), but free and<br />unconditioned accessibility seemed not to be common practice. The analysis of the guidelines regarding the accessibility to resources of the biobanks that responded to the survey highlights three issues: (i) the request for applicants to explain what they would like to do with the resources requested; (ii) the role of funding, public or private, in the establishment of fruitful collaborations between biobanks and research labs; (iii)<br />the request of co-authorship in order to give access to their data. These results suggest that economic and academic aspects are involved in determining the extent of sample and data sharing stored in biobanks. As a second step of this study, we investigated<br />the reasons behind the high diversity of requirements to access biobank resources. The analysis of informative answers suggested that the different modalities of resource accessibility seem to be largely influenced by both social context and legislation of the countries where the biobanks operate.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8d68b4c962e74cf4b9e93c520c2ab9bb" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":43165905,"asset_id":22552525,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/43165905/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="22552525"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="22552525"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22552525; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22552525]").text(description); $(".js-view-count[data-work-id=22552525]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 22552525; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='22552525']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 22552525, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8d68b4c962e74cf4b9e93c520c2ab9bb" } } $('.js-work-strip[data-work-id=22552525]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":22552525,"title":"Samples and data accessibility in research biobanks: an explorative survey","translated_title":"","metadata":{"abstract":"Biobanks, which contain human biological samples and/or data, provide a crucial contribution to the progress of biomedical research. However, the effective and efficient use of biobank resources depends on their accessibility. In fact, making bio-resources promptly accessible to everybody may increase the benefits for society. Furthermore, optimizing their use and ensuring their quality will promote scientific creativity and, in general, contribute to the progress of bio-medical research. Although this has become a rather common belief, several laboratories are still secretive and continue to withhold samples and data. In this study, we conducted a questionnaire-\nbased survey in order to investigate sample and data accessibility in research biobanks operating all over the world. The survey involved a total of 46 biobanks. Most of them gave permission to access their samples (95.7%) and data (85.4%), but free and\nunconditioned accessibility seemed not to be common practice. The analysis of the guidelines regarding the accessibility to resources of the biobanks that responded to the survey highlights three issues: (i) the request for applicants to explain what they would like to do with the resources requested; (ii) the role of funding, public or private, in the establishment of fruitful collaborations between biobanks and research labs; (iii)\nthe request of co-authorship in order to give access to their data. These results suggest that economic and academic aspects are involved in determining the extent of sample and data sharing stored in biobanks. As a second step of this study, we investigated\nthe reasons behind the high diversity of requirements to access biobank resources. The analysis of informative answers suggested that the different modalities of resource accessibility seem to be largely influenced by both social context and legislation of the countries where the biobanks operate."},"translated_abstract":"Biobanks, which contain human biological samples and/or data, provide a crucial contribution to the progress of biomedical research. However, the effective and efficient use of biobank resources depends on their accessibility. In fact, making bio-resources promptly accessible to everybody may increase the benefits for society. Furthermore, optimizing their use and ensuring their quality will promote scientific creativity and, in general, contribute to the progress of bio-medical research. Although this has become a rather common belief, several laboratories are still secretive and continue to withhold samples and data. In this study, we conducted a questionnaire-\nbased survey in order to investigate sample and data accessibility in research biobanks operating all over the world. The survey involved a total of 46 biobanks. Most of them gave permission to access their samples (95.7%) and data (85.4%), but free and\nunconditioned accessibility seemed not to be common practice. The analysis of the guidelines regarding the accessibility to resources of the biobanks that responded to the survey highlights three issues: (i) the request for applicants to explain what they would like to do with the resources requested; (ii) the role of funding, public or private, in the establishment of fruitful collaborations between biobanks and research labs; (iii)\nthe request of co-authorship in order to give access to their data. These results suggest that economic and academic aspects are involved in determining the extent of sample and data sharing stored in biobanks. 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resources? The case of research biobanks" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/20489646/Sharing_standards_before_sharing_resources_The_case_of_research_biobanks">Sharing standards before sharing resources? The case of research biobanks</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In biobank research, one of the main obstacles for full applicability of Open Access to biomedica...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In biobank research, one of the main obstacles for full applicability of Open Access to biomedical resources is the researchers’ reluctance to make immediately and freely available these materials before having adequately exploited their potential. To analyse this issue from a wider perspective, we need to consider the role of research biobanks as main repositories in which human biological samples are stored, with or without accompanying them with genetic or clinical data (Haga and Beskow 2008). If withholding of biobanks’ resources drastically reduces their full value, their wide sharing is not simple to put into practice. The first and most complex barrier hindering Open Access is the lack of common standards, guidelines and legal frameworks due to socio-cultural differences of countries where biobanks operate (see Capocasa et al 2015 <a href="https://peerj.com/preprints/1212/" rel="nofollow">https://peerj.com/preprints/1212/</a>). 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="15749984"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/15749984/Research_participants_perceptions_and_views_on_consent_for_biobank_research_a_review_of_empirical_data_and_ethical_analysis"><img alt="Research paper thumbnail of Research participants’ perceptions and views on consent for biobank research: a review of empirical data and ethical analysis" class="work-thumbnail" src="https://attachments.academia-assets.com/38811191/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/15749984/Research_participants_perceptions_and_views_on_consent_for_biobank_research_a_review_of_empirical_data_and_ethical_analysis">Research participants’ perceptions and views on consent for biobank research: a review of empirical data and ethical analysis</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background Appropriate information and consent has been one of the most intensely discussed topic...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background<br />Appropriate information and consent has been one of the most intensely discussed topics within the context of biobank research. In parallel to the normative debate, many socio-empirical studies have been conducted to gather experiences, preferences and views of patients, healthy research participants and further stakeholders. However, there is scarcity of literature which connects the normative debate about justifications for different consent models with findings gained in empirical research. In this paper we discuss findings of a limited review of socio-empirical research on patients’ and healthy research participants’ experiences and views regarding consent to biobank research in light of ethical principles for appropriate information and consent.<br /><br />Methods<br />Review question: Which empirical data are available on research participants’ perceptions and views regarding information and elicitation of consent for biobank research? Search of articles published till March 1st 2014 in Pubmed. Review of abstracts and potentially relevant full text articles by two authors independently. As categories for content analysis we defined (i) understanding or recall of information, (ii) preferences regarding information or consent, and (iii) research participants’ concerns.<br /><br />Results<br />The search in Pubmed yielded 337 abstracts of which 10 articles were included in this study. Approaches to information and consent varied considerably across the selected studies. The majority of research participants opted for some version of limited consent when being informed about such possibility. Among the factors influencing the type of preferred consent were information about sponsoring of biobank research by pharmaceutical industry and participants’ trade-off between privacy and perceived utility. Studies investigating research participants’ understanding and recall regarding the consent procedure indicated considerable lack of both aspects. Research participants’ perceptions of benefits and harms differ across those studies.<br /><br />Conclusion<br />The knowledge, perceptions and views of research participants who have undergone a consent procedure within the context of biobank research raise several questions on the issue of how to inform and elicit consent in an ethically acceptable way. In our empirical-ethical analysis we develop suggestions on how the practice of eliciting consent in the biobank context should be improved.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="350792280a305ca64675868ec331e851" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":38811191,"asset_id":15749984,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/38811191/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="15749984"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="15749984"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 15749984; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=15749984]").text(description); $(".js-view-count[data-work-id=15749984]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 15749984; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='15749984']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 15749984, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "350792280a305ca64675868ec331e851" } } $('.js-work-strip[data-work-id=15749984]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":15749984,"title":"Research participants’ perceptions and views on consent for biobank research: a review of empirical data and ethical analysis","translated_title":"","metadata":{"abstract":"Background\nAppropriate information and consent has been one of the most intensely discussed topics within the context of biobank research. In parallel to the normative debate, many socio-empirical studies have been conducted to gather experiences, preferences and views of patients, healthy research participants and further stakeholders. However, there is scarcity of literature which connects the normative debate about justifications for different consent models with findings gained in empirical research. In this paper we discuss findings of a limited review of socio-empirical research on patients’ and healthy research participants’ experiences and views regarding consent to biobank research in light of ethical principles for appropriate information and consent.\n\nMethods\nReview question: Which empirical data are available on research participants’ perceptions and views regarding information and elicitation of consent for biobank research? Search of articles published till March 1st 2014 in Pubmed. Review of abstracts and potentially relevant full text articles by two authors independently. As categories for content analysis we defined (i) understanding or recall of information, (ii) preferences regarding information or consent, and (iii) research participants’ concerns.\n\nResults\nThe search in Pubmed yielded 337 abstracts of which 10 articles were included in this study. Approaches to information and consent varied considerably across the selected studies. The majority of research participants opted for some version of limited consent when being informed about such possibility. Among the factors influencing the type of preferred consent were information about sponsoring of biobank research by pharmaceutical industry and participants’ trade-off between privacy and perceived utility. Studies investigating research participants’ understanding and recall regarding the consent procedure indicated considerable lack of both aspects. Research participants’ perceptions of benefits and harms differ across those studies.\n\nConclusion\nThe knowledge, perceptions and views of research participants who have undergone a consent procedure within the context of biobank research raise several questions on the issue of how to inform and elicit consent in an ethically acceptable way. In our empirical-ethical analysis we develop suggestions on how the practice of eliciting consent in the biobank context should be improved.\n"},"translated_abstract":"Background\nAppropriate information and consent has been one of the most intensely discussed topics within the context of biobank research. In parallel to the normative debate, many socio-empirical studies have been conducted to gather experiences, preferences and views of patients, healthy research participants and further stakeholders. However, there is scarcity of literature which connects the normative debate about justifications for different consent models with findings gained in empirical research. In this paper we discuss findings of a limited review of socio-empirical research on patients’ and healthy research participants’ experiences and views regarding consent to biobank research in light of ethical principles for appropriate information and consent.\n\nMethods\nReview question: Which empirical data are available on research participants’ perceptions and views regarding information and elicitation of consent for biobank research? Search of articles published till March 1st 2014 in Pubmed. Review of abstracts and potentially relevant full text articles by two authors independently. As categories for content analysis we defined (i) understanding or recall of information, (ii) preferences regarding information or consent, and (iii) research participants’ concerns.\n\nResults\nThe search in Pubmed yielded 337 abstracts of which 10 articles were included in this study. Approaches to information and consent varied considerably across the selected studies. The majority of research participants opted for some version of limited consent when being informed about such possibility. Among the factors influencing the type of preferred consent were information about sponsoring of biobank research by pharmaceutical industry and participants’ trade-off between privacy and perceived utility. Studies investigating research participants’ understanding and recall regarding the consent procedure indicated considerable lack of both aspects. Research participants’ perceptions of benefits and harms differ across those studies.\n\nConclusion\nThe knowledge, perceptions and views of research participants who have undergone a consent procedure within the context of biobank research raise several questions on the issue of how to inform and elicit consent in an ethically acceptable way. In our empirical-ethical analysis we develop suggestions on how the practice of eliciting consent in the biobank context should be improved.\n","internal_url":"https://www.academia.edu/15749984/Research_participants_perceptions_and_views_on_consent_for_biobank_research_a_review_of_empirical_data_and_ethical_analysis","translated_internal_url":"","created_at":"2015-09-16T00:35:34.752-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":5995822,"work_id":15749984,"tagging_user_id":1231121,"tagged_user_id":null,"co_author_invite_id":1321924,"email":"j***n@rub.de","display_order":0,"name":"Jan Schildmann","title":"Research participants’ perceptions and views on consent for biobank research: a review of empirical data and ethical analysis"}],"downloadable_attachments":[{"id":38811191,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/38811191/thumbnails/1.jpg","file_name":"12910_2015_Article_53.pdf","download_url":"https://www.academia.edu/attachments/38811191/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Research_participants_perceptions_and_vi.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/38811191/12910_2015_Article_53-libre.pdf?1442609126=\u0026response-content-disposition=attachment%3B+filename%3DResearch_participants_perceptions_and_vi.pdf\u0026Expires=1732799329\u0026Signature=JZBRFuxQ5GO3Aj3UTIRGpibvDcQVhR9wbiBEVOkezo7~CZTrpRWGLzjLxgZ2UlFGgb17Z97fRMflkF1JRhkaSK-0ZHJnQngx3JJEqPop97mfUAxWNRvAT793ZCC04qBoGHul7fYSE4VWiRGPXBRCk6KiC1-qXlD7SiWZs-KVKXBxyOfbY8ld1TJKSqUqt-OwehF9baGPGtFONvDgA4qa-36DzIKSWhH0DW7hKrZg2d-bne6Oy1ZzoByySpLH4~UtQIkPzCYRYG6tR8ONtllut96MaHDWqsQYfF5c046kvgqGZCbkly8Omh2oVVOydJNoPKaT7gHtalAXyOZyKeKzuQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Research_participants_perceptions_and_views_on_consent_for_biobank_research_a_review_of_empirical_data_and_ethical_analysis","translated_slug":"","page_count":11,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[{"id":38811191,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/38811191/thumbnails/1.jpg","file_name":"12910_2015_Article_53.pdf","download_url":"https://www.academia.edu/attachments/38811191/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Research_participants_perceptions_and_vi.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/38811191/12910_2015_Article_53-libre.pdf?1442609126=\u0026response-content-disposition=attachment%3B+filename%3DResearch_participants_perceptions_and_vi.pdf\u0026Expires=1732799329\u0026Signature=JZBRFuxQ5GO3Aj3UTIRGpibvDcQVhR9wbiBEVOkezo7~CZTrpRWGLzjLxgZ2UlFGgb17Z97fRMflkF1JRhkaSK-0ZHJnQngx3JJEqPop97mfUAxWNRvAT793ZCC04qBoGHul7fYSE4VWiRGPXBRCk6KiC1-qXlD7SiWZs-KVKXBxyOfbY8ld1TJKSqUqt-OwehF9baGPGtFONvDgA4qa-36DzIKSWhH0DW7hKrZg2d-bne6Oy1ZzoByySpLH4~UtQIkPzCYRYG6tR8ONtllut96MaHDWqsQYfF5c046kvgqGZCbkly8Omh2oVVOydJNoPKaT7gHtalAXyOZyKeKzuQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":2504,"name":"Research Ethics","url":"https://www.academia.edu/Documents/in/Research_Ethics"},{"id":8562,"name":"Informed Consent","url":"https://www.academia.edu/Documents/in/Informed_Consent"},{"id":101544,"name":"Biobanking","url":"https://www.academia.edu/Documents/in/Biobanking"},{"id":102044,"name":"Biobanking and Society","url":"https://www.academia.edu/Documents/in/Biobanking_and_Society"},{"id":1372737,"name":"Genomics Research","url":"https://www.academia.edu/Documents/in/Genomics_Research"}],"urls":[{"id":5416591,"url":"http://www.ncbi.nlm.nih.gov/pubmed/?term=10.1186/s12910-015-0053-5"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="12602852"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/12602852/Il_consenso_informato_in_ambito_terapeutico_Tra_autonomia_del_paziente_e_medicina_difensiva"><img alt="Research paper thumbnail of Il consenso informato in ambito terapeutico. Tra autonomia del paziente e medicina difensiva" class="work-thumbnail" src="https://attachments.academia-assets.com/37740189/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/12602852/Il_consenso_informato_in_ambito_terapeutico_Tra_autonomia_del_paziente_e_medicina_difensiva">Il consenso informato in ambito terapeutico. Tra autonomia del paziente e medicina difensiva</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">1. Breve storia del consenso informato Prime spinte verso il consenso informato La dichiarazione...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">1. Breve storia del consenso informato<br />Prime spinte verso il consenso informato <br />La dichiarazione di Helsinki<br />La convenzione di Oviedo<br />Il consenso informato nella regolamentazione italiana <br />Per riassumere <br /><br />2. Breve introduzione all’evoluzione bioetica del consenso informato<br />La medicina paternalistica e il principio di beneficità <br />Il principio di autodeterminazione, lo shared decision making, e l’empowerment del paziente<br />La trasparenza nel rapporto medico/paziente<br />Per riassumere <br /><br />3. Dal consenso informato alla decisione autonoma e informata<br />Il consenso informato tra efficacia terapeutica ed equità <br />Equità, giustizia sociale e medicina difensiva <br />Per riassumere <br /><br />Conclusioni <br /><br />Riferimenti Bibliografici</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="61534c7bcca97148459db4d144f883da" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37740189,"asset_id":12602852,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37740189/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="12602852"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="12602852"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 12602852; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=12602852]").text(description); $(".js-view-count[data-work-id=12602852]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 12602852; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='12602852']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 12602852, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "61534c7bcca97148459db4d144f883da" } } $('.js-work-strip[data-work-id=12602852]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":12602852,"title":"Il consenso informato in ambito terapeutico. Tra autonomia del paziente e medicina difensiva","translated_title":"","metadata":{"abstract":"1. Breve storia del consenso informato\nPrime spinte verso il consenso informato \nLa dichiarazione di Helsinki\nLa convenzione di Oviedo\nIl consenso informato nella regolamentazione italiana \nPer riassumere \n\n2. Breve introduzione all’evoluzione bioetica del consenso informato\nLa medicina paternalistica e il principio di beneficità \nIl principio di autodeterminazione, lo shared decision making, e l’empowerment del paziente\nLa trasparenza nel rapporto medico/paziente\nPer riassumere \n\n3. Dal consenso informato alla decisione autonoma e informata\nIl consenso informato tra efficacia terapeutica ed equità \nEquità, giustizia sociale e medicina difensiva \nPer riassumere \n\nConclusioni \n\nRiferimenti Bibliografici "},"translated_abstract":"1. Breve storia del consenso informato\nPrime spinte verso il consenso informato \nLa dichiarazione di Helsinki\nLa convenzione di Oviedo\nIl consenso informato nella regolamentazione italiana \nPer riassumere \n\n2. Breve introduzione all’evoluzione bioetica del consenso informato\nLa medicina paternalistica e il principio di beneficità \nIl principio di autodeterminazione, lo shared decision making, e l’empowerment del paziente\nLa trasparenza nel rapporto medico/paziente\nPer riassumere \n\n3. Dal consenso informato alla decisione autonoma e informata\nIl consenso informato tra efficacia terapeutica ed equità \nEquità, giustizia sociale e medicina difensiva \nPer riassumere \n\nConclusioni \n\nRiferimenti Bibliografici ","internal_url":"https://www.academia.edu/12602852/Il_consenso_informato_in_ambito_terapeutico_Tra_autonomia_del_paziente_e_medicina_difensiva","translated_internal_url":"","created_at":"2015-05-26T04:21:45.039-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":37740189,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37740189/thumbnails/1.jpg","file_name":"Il_Consenso_informato.pdf","download_url":"https://www.academia.edu/attachments/37740189/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Il_consenso_informato_in_ambito_terapeut.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37740189/Il_Consenso_informato-libre.pdf?1432639336=\u0026response-content-disposition=attachment%3B+filename%3DIl_consenso_informato_in_ambito_terapeut.pdf\u0026Expires=1732799329\u0026Signature=M6sIo31jPEYsvtcabRng-u7OOcrATHu6wu7UO0wdzR0OdnNoJE8i7Z-KcgsHIc6H9YnXX2HYos7SDxRhlAhQxREc-ymE9PKRhcflPk0cE6uIsP-eJJNVY-xQBBODv0j18fOKDsgnWIvgk6B~a3KHeChw5P1RIT0pBBqy8SuNO1QrSYdGIE-sn8vSfEEcUgRnw-optvxcE4K3Ccn1Qp1NqwD05yVpXeHkLJ5NihrrxFw5xXUOLvUBKE5RGri48iKeWKMWxDqzopNjFh6SlwbirPMzlq64J1tRU04tVZ932B37luLxUR9BtBB48FZ4fDMRTrkKxL006WA1jgQbWmQe2Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Il_consenso_informato_in_ambito_terapeutico_Tra_autonomia_del_paziente_e_medicina_difensiva","translated_slug":"","page_count":32,"language":"it","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[{"id":37740189,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37740189/thumbnails/1.jpg","file_name":"Il_Consenso_informato.pdf","download_url":"https://www.academia.edu/attachments/37740189/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Il_consenso_informato_in_ambito_terapeut.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37740189/Il_Consenso_informato-libre.pdf?1432639336=\u0026response-content-disposition=attachment%3B+filename%3DIl_consenso_informato_in_ambito_terapeut.pdf\u0026Expires=1732799329\u0026Signature=M6sIo31jPEYsvtcabRng-u7OOcrATHu6wu7UO0wdzR0OdnNoJE8i7Z-KcgsHIc6H9YnXX2HYos7SDxRhlAhQxREc-ymE9PKRhcflPk0cE6uIsP-eJJNVY-xQBBODv0j18fOKDsgnWIvgk6B~a3KHeChw5P1RIT0pBBqy8SuNO1QrSYdGIE-sn8vSfEEcUgRnw-optvxcE4K3Ccn1Qp1NqwD05yVpXeHkLJ5NihrrxFw5xXUOLvUBKE5RGri48iKeWKMWxDqzopNjFh6SlwbirPMzlq64J1tRU04tVZ932B37luLxUR9BtBB48FZ4fDMRTrkKxL006WA1jgQbWmQe2Q__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":8470,"name":"Empowerment","url":"https://www.academia.edu/Documents/in/Empowerment"},{"id":8562,"name":"Informed Consent","url":"https://www.academia.edu/Documents/in/Informed_Consent"},{"id":9795,"name":"Personal and Moral Autonomy","url":"https://www.academia.edu/Documents/in/Personal_and_Moral_Autonomy"},{"id":11758,"name":"Health insurance","url":"https://www.academia.edu/Documents/in/Health_insurance"},{"id":59537,"name":"Transparency","url":"https://www.academia.edu/Documents/in/Transparency"},{"id":138182,"name":"Patient Empowerment","url":"https://www.academia.edu/Documents/in/Patient_Empowerment"},{"id":192647,"name":"Health Equality","url":"https://www.academia.edu/Documents/in/Health_Equality"},{"id":340689,"name":"Defensive Medicine","url":"https://www.academia.edu/Documents/in/Defensive_Medicine"},{"id":340691,"name":"Defensive Medicien \u0026 Litigation","url":"https://www.academia.edu/Documents/in/Defensive_Medicien_and_Litigation"},{"id":607831,"name":"Trasparenza","url":"https://www.academia.edu/Documents/in/Trasparenza"},{"id":817963,"name":"Principio Di Autodeterminazione","url":"https://www.academia.edu/Documents/in/Principio_Di_Autodeterminazione"},{"id":990734,"name":"Health Care Evaluation of Effectiveness","url":"https://www.academia.edu/Documents/in/Health_Care_Evaluation_of_Effectiveness"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="10701225"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/10701225/Biobank_research_informed_consent_and_society_Towards_a_new_alliance"><img alt="Research paper thumbnail of Biobank research, informed consent and society. Towards a new alliance?" class="work-thumbnail" src="https://attachments.academia-assets.com/37290670/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/10701225/Biobank_research_informed_consent_and_society_Towards_a_new_alliance">Biobank research, informed consent and society. Towards a new alliance?</a></div><div class="wp-workCard_item"><span>Journal of Epidemiology and Community Health</span><span>, Feb 10, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">With the rise of -omics disciplines and biobank research, personal data and biosamples crossing n...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">With the rise of -omics disciplines and biobank research, personal data and biosamples crossing national borders pose new ethical questions. In this article, informed consent, as originally conceived, is shown as not being sufficient to address aims of research and interests of patients any more. Therefore the author has, after having scrutinised issues in biobanking, sketched a model of dynamic consent and a manner of scrutinising ethical issues through empirical data.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="993f626b7fc824c8c15ac13d6937f8a9" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":37290670,"asset_id":10701225,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/37290670/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="10701225"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="10701225"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 10701225; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=10701225]").text(description); $(".js-view-count[data-work-id=10701225]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 10701225; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='10701225']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 10701225, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "993f626b7fc824c8c15ac13d6937f8a9" } } $('.js-work-strip[data-work-id=10701225]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":10701225,"title":"Biobank research, informed consent and society. Towards a new alliance?","translated_title":"","metadata":{"abstract":"With the rise of -omics disciplines and biobank research, personal data and biosamples crossing national borders pose new ethical questions. In this article, informed consent, as originally conceived, is shown as not being sufficient to address aims of research and interests of patients any more. Therefore the author has, after having scrutinised issues in biobanking, sketched a model of dynamic consent and a manner of scrutinising ethical issues through empirical data.","publication_date":{"day":10,"month":2,"year":2015,"errors":{}},"publication_name":"Journal of Epidemiology and Community Health"},"translated_abstract":"With the rise of -omics disciplines and biobank research, personal data and biosamples crossing national borders pose new ethical questions. In this article, informed consent, as originally conceived, is shown as not being sufficient to address aims of research and interests of patients any more. Therefore the author has, after having scrutinised issues in biobanking, sketched a model of dynamic consent and a manner of scrutinising ethical issues through empirical data.","internal_url":"https://www.academia.edu/10701225/Biobank_research_informed_consent_and_society_Towards_a_new_alliance","translated_internal_url":"","created_at":"2015-02-11T04:04:40.012-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":37290670,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37290670/thumbnails/1.jpg","file_name":"jech-2014-205215.full.pdf","download_url":"https://www.academia.edu/attachments/37290670/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Biobank_research_informed_consent_and_so.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37290670/jech-2014-205215.full-libre.pdf?1428930463=\u0026response-content-disposition=attachment%3B+filename%3DBiobank_research_informed_consent_and_so.pdf\u0026Expires=1732799329\u0026Signature=aILN6w6AcyQEVJiobiN4uzKGGKB53lQ4BTDbredVsvSLLnMr5UBHnrOStEV0A56aLNsIaTLaEc3i1850l-LkBrw8-CvXjL5Gh18yg7kB0cLsrImPN8-sHiQYjWS3vQxv9adE8dDrUaK5cZNc7q9wcZYx8ifijbNMOnaUWsLNb4DsK32-s4BlN8MWl9YcInTEy1KQEXWeZtei68GkyfJB2s7ZIOD5J6F6dCfJmAC5R~urRBB48hsIi3J5a-TU~6D3nbXjoMJbQ8IhDF5ABsY9vXIYBDyfs~mTtwGv7SZZLGkQ9hdj8mwa9~z1ZBnmkqdeb9z0-L9vRBslwlYw9lhPmQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Biobank_research_informed_consent_and_society_Towards_a_new_alliance","translated_slug":"","page_count":4,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[{"id":37290670,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/37290670/thumbnails/1.jpg","file_name":"jech-2014-205215.full.pdf","download_url":"https://www.academia.edu/attachments/37290670/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Biobank_research_informed_consent_and_so.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/37290670/jech-2014-205215.full-libre.pdf?1428930463=\u0026response-content-disposition=attachment%3B+filename%3DBiobank_research_informed_consent_and_so.pdf\u0026Expires=1732799330\u0026Signature=RLM3tFqHrUOuvUI5XjslnX9FIDAkVYrNLMVXNEva6jKT8noDvlUj8pJJ1hYvH65QxeE6LTdTf7dk4jx790QAJCbvKenM-z5KzaSVwANOoPtqrPXbt6vlzgrGCMQTqBSMdORkTV0HP5Sd72E7EvE3~bo7JG0LjI~~XtpjRK~8xv2HbY1xwTqcI-2BGL2f1TQZYnNmcgqonKFFHOP1AIjIoKqloUo~bdkkKKQQvS2CiwJCOrtl4FraCSwK2fM6Sg56UW5sv-TBbmEaKkLmKk2TF6z3B2NptY33oMd61Oa6EgjROEuQprPnQRDxy1RrQCwSjlOnM9qF3bJ4NK4rzdN~4g__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1414,"name":"Bioethics","url":"https://www.academia.edu/Documents/in/Bioethics"},{"id":2504,"name":"Research Ethics","url":"https://www.academia.edu/Documents/in/Research_Ethics"},{"id":3216,"name":"Genomics","url":"https://www.academia.edu/Documents/in/Genomics"},{"id":6439,"name":"Public Understanding Of Science","url":"https://www.academia.edu/Documents/in/Public_Understanding_Of_Science"},{"id":8562,"name":"Informed Consent","url":"https://www.academia.edu/Documents/in/Informed_Consent"},{"id":9200,"name":"Science, Technology and Society","url":"https://www.academia.edu/Documents/in/Science_Technology_and_Society"},{"id":111394,"name":"Biobanks","url":"https://www.academia.edu/Documents/in/Biobanks"},{"id":156875,"name":"Empirical Ethics","url":"https://www.academia.edu/Documents/in/Empirical_Ethics"}],"urls":[{"id":4588029,"url":"http://jech.bmj.com/content/early/2015/02/10/jech-2014-205215.short?g=w_jech_ahead_tab"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="1762036"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/1762036/Traslation_of_cancer_molecular_biomarkers_ethical_and_epistemological_issues"><img alt="Research paper thumbnail of Traslation of cancer molecular biomarkers ethical and epistemological issues" class="work-thumbnail" src="https://attachments.academia-assets.com/31941320/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/1762036/Traslation_of_cancer_molecular_biomarkers_ethical_and_epistemological_issues">Traslation of cancer molecular biomarkers ethical and epistemological issues</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The phenomenon of high cancer mortality has been the key factor in driving drug approval processe...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The phenomenon of high cancer mortality has been the key factor in driving drug approval processes and health-care policies. In this paper, we discuss the inconsistencies of the genetic model of cancer as applied in the case of colorectal cancer (CRC). The result of relying on a genetic model of CRC is the approval of cancer drugs based on the inhibition of the epidermal growth factor receptor. The poor clinical performance of these drugs has prompted the use of a molecular biomarker to find the respondent patients. Due to the complexity of the cancer cell biological pathways, even the use of a molecular biomarker has not improved the clinical response of treated patients. Within the clinical uncertainty derived from the limited predictive value of a cancer molecular biomarker, we analyse the patient-doctor relationship. Beyond the challenge of communicating the medical uncertainty, many influences coming from the health-care system make the medical decisions biased. We analyse the ethical justification in using drugs that, at best, extend the patients’ survival for a few weeks, then we proceed to highlight the excessive cost of these drugs that create a problem for the allocation of resources for the whole society. We hold that a sensitive evaluation before the use of costly drugs for metastatic cancers must enter into the physician-patient relationship balancing the ethical concerns of the oncologist community and the need for the development of preventive policies.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5e725e376c6caea151e631c86d8c559a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":31941320,"asset_id":1762036,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/31941320/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="1762036"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="1762036"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 1762036; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=1762036]").text(description); $(".js-view-count[data-work-id=1762036]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 1762036; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='1762036']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 1762036, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "5e725e376c6caea151e631c86d8c559a" } } $('.js-work-strip[data-work-id=1762036]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":1762036,"title":"Traslation of cancer molecular biomarkers ethical and epistemological issues","translated_title":"","metadata":{"abstract":"The phenomenon of high cancer mortality has been the key factor in driving drug approval processes and health-care policies. 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Analisi epistemologica della relazione tra genetica ed epigenetica." class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/1765472/La_diversit%C3%A0_biologica_Analisi_epistemologica_della_relazione_tra_genetica_ed_epigenetica">La diversità biologica. Analisi epistemologica della relazione tra genetica ed epigenetica.</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The first part of the thesis is a critical analysis of the proceedings of the conferences&amp;quo...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The first part of the thesis is a critical analysis of the proceedings of the conferences&amp;quot; Towards a Theoretical Biology&amp;quot; founded by the Rockefeller Foundation and leaded by Conrad H. Waddington. The second part is an epistemological and sociological analysis ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="1765472"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="1765472"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 1765472; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=1765472]").text(description); $(".js-view-count[data-work-id=1765472]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 1765472; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='1765472']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 1765472, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=1765472]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":1765472,"title":"La diversità biologica. 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The second part is an epistemological and sociological analysis ...","internal_url":"https://www.academia.edu/1765472/La_diversit%C3%A0_biologica_Analisi_epistemologica_della_relazione_tra_genetica_ed_epigenetica","translated_internal_url":"","created_at":"2012-07-04T20:10:38.477-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"La_diversità_biologica_Analisi_epistemologica_della_relazione_tra_genetica_ed_epigenetica","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[],"research_interests":[{"id":823,"name":"Philosophy of Biology","url":"https://www.academia.edu/Documents/in/Philosophy_of_Biology"}],"urls":[{"id":301501,"url":"http://padis.uniroma1.it/handle/10805/1548"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="11324606"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/11324606/Some_historical_and_epistemological_remarks_on_genetics_and_epigenetics"><img alt="Research paper thumbnail of Some historical and epistemological remarks on genetics and epigenetics" class="work-thumbnail" src="https://attachments.academia-assets.com/36897035/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/11324606/Some_historical_and_epistemological_remarks_on_genetics_and_epigenetics">Some historical and epistemological remarks on genetics and epigenetics</a></div><div class="wp-workCard_item"><span>Mateus DOC VI - CODIGO - proceedings </span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In the article some remarks are made on the birth and development of genetics and epigenetics, an...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In the article some remarks are made on the birth and development of genetics and epigenetics, and in respect of their relationship with environmental factors. If Johannsen’s genotype concept is a reprise of Woltereck’s Norm of Reaction, is also true that the former excluded the important role of environmental factors considered by the latter. Then, I describe some operational concepts taken from Woltereck’s Norm of Reaction and that through the work of Krafka and Hersch were transferred to Conrad Waddington in the contemporary biological debate. In the light of the role that epigenetics confers to the interaction between environmental factors and organisms’ development, the importance of the genetic code is questioned.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="f1c6b525417bb48dd8812f740142774a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":36897035,"asset_id":11324606,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/36897035/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="11324606"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="11324606"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 11324606; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=11324606]").text(description); $(".js-view-count[data-work-id=11324606]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 11324606; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='11324606']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 11324606, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "f1c6b525417bb48dd8812f740142774a" } } $('.js-work-strip[data-work-id=11324606]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":11324606,"title":"Some historical and epistemological remarks on genetics and epigenetics","translated_title":"","metadata":{"abstract":"In the article some remarks are made on the birth and development of genetics and epigenetics, and in respect of their relationship with environmental factors. If Johannsen’s genotype concept is a reprise of Woltereck’s Norm of Reaction, is also true that the former excluded the important role of environmental factors considered by the latter. Then, I describe some operational concepts taken from Woltereck’s Norm of Reaction and that through the work of Krafka and Hersch were transferred to Conrad Waddington in the contemporary biological debate. In the light of the role that epigenetics confers to the interaction between environmental factors and organisms’ development, the importance of the genetic code is questioned.","publication_name":"Mateus DOC VI - CODIGO - proceedings "},"translated_abstract":"In the article some remarks are made on the birth and development of genetics and epigenetics, and in respect of their relationship with environmental factors. If Johannsen’s genotype concept is a reprise of Woltereck’s Norm of Reaction, is also true that the former excluded the important role of environmental factors considered by the latter. Then, I describe some operational concepts taken from Woltereck’s Norm of Reaction and that through the work of Krafka and Hersch were transferred to Conrad Waddington in the contemporary biological debate. 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Sulla scia della divisione del mondo nei blocchi delineati durante la guerra fredda, l’epigenetica venne osteggiata dalle più importanti istituzioni scientifiche occidentali di inizio Novecento e dimenticata fino alla fine degli anni sessanta. Uno dei motivi di questo ostracismo da parte degli ambienti accademici risiedeva nel carattere di forte interdisciplinarità della sua genesi – prerogativa propria della scienza sovietica – mentre nell’assetto scientifico del blocco occidentale la specializzazione disciplinare e il conseguente ruolo degli esperti nelle istituzioni democratiche iniziava a prendere piede. Dopo aver percorso le tappe storiche dello sviluppo dell’epigenetica, vengono analizzati casi di studio in cui questa disciplina interagisce con la zoologia, la botanica e la sfera della salute pubblica per le generazioni presenti e future, nonché le linee di ricerca più recenti che aprono al ripensamento dei cardini culturali e scientifici delle nostre stesse società.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="37319932"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="37319932"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 37319932; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=37319932]").text(description); $(".js-view-count[data-work-id=37319932]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 37319932; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='37319932']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 37319932, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=37319932]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":37319932,"title":"L'epigenetica","translated_title":"","metadata":{"abstract":"ll volume introduce il lettore all’epigenetica, lo studio biologico della continuità tra organismi e ambienti, attraverso la sua storia e le sue attuali applicazioni nella salute pubblica e nella ricerca scientifica. Sulla scia della divisione del mondo nei blocchi delineati durante la guerra fredda, l’epigenetica venne osteggiata dalle più importanti istituzioni scientifiche occidentali di inizio Novecento e dimenticata fino alla fine degli anni sessanta. Uno dei motivi di questo ostracismo da parte degli ambienti accademici risiedeva nel carattere di forte interdisciplinarità della sua genesi – prerogativa propria della scienza sovietica – mentre nell’assetto scientifico del blocco occidentale la specializzazione disciplinare e il conseguente ruolo degli esperti nelle istituzioni democratiche iniziava a prendere piede. Dopo aver percorso le tappe storiche dello sviluppo dell’epigenetica, vengono analizzati casi di studio in cui questa disciplina interagisce con la zoologia, la botanica e la sfera della salute pubblica per le generazioni presenti e future, nonché le linee di ricerca più recenti che aprono al ripensamento dei cardini culturali e scientifici delle nostre stesse società."},"translated_abstract":"ll volume introduce il lettore all’epigenetica, lo studio biologico della continuità tra organismi e ambienti, attraverso la sua storia e le sue attuali applicazioni nella salute pubblica e nella ricerca scientifica. Sulla scia della divisione del mondo nei blocchi delineati durante la guerra fredda, l’epigenetica venne osteggiata dalle più importanti istituzioni scientifiche occidentali di inizio Novecento e dimenticata fino alla fine degli anni sessanta. Uno dei motivi di questo ostracismo da parte degli ambienti accademici risiedeva nel carattere di forte interdisciplinarità della sua genesi – prerogativa propria della scienza sovietica – mentre nell’assetto scientifico del blocco occidentale la specializzazione disciplinare e il conseguente ruolo degli esperti nelle istituzioni democratiche iniziava a prendere piede. Dopo aver percorso le tappe storiche dello sviluppo dell’epigenetica, vengono analizzati casi di studio in cui questa disciplina interagisce con la zoologia, la botanica e la sfera della salute pubblica per le generazioni presenti e future, nonché le linee di ricerca più recenti che aprono al ripensamento dei cardini culturali e scientifici delle nostre stesse società.","internal_url":"https://www.academia.edu/37319932/Lepigenetica","translated_internal_url":"","created_at":"2018-08-30T23:35:31.793-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"book","co_author_tags":[],"downloadable_attachments":[],"slug":"Lepigenetica","translated_slug":"","page_count":null,"language":"it","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[],"research_interests":[{"id":1414,"name":"Bioethics","url":"https://www.academia.edu/Documents/in/Bioethics"},{"id":2273,"name":"History of Medicine","url":"https://www.academia.edu/Documents/in/History_of_Medicine"},{"id":2513,"name":"Molecular Biology","url":"https://www.academia.edu/Documents/in/Molecular_Biology"},{"id":3407,"name":"Environmental Studies","url":"https://www.academia.edu/Documents/in/Environmental_Studies"},{"id":3723,"name":"History of Science","url":"https://www.academia.edu/Documents/in/History_of_Science"},{"id":4440,"name":"Philosophy of Medicine","url":"https://www.academia.edu/Documents/in/Philosophy_of_Medicine"},{"id":9435,"name":"Medical Ethics","url":"https://www.academia.edu/Documents/in/Medical_Ethics"},{"id":13075,"name":"History of Biology","url":"https://www.academia.edu/Documents/in/History_of_Biology"},{"id":16323,"name":"Biopolitics","url":"https://www.academia.edu/Documents/in/Biopolitics"},{"id":21500,"name":"Social Studies Of Science","url":"https://www.academia.edu/Documents/in/Social_Studies_Of_Science"},{"id":22404,"name":"Epigenetics","url":"https://www.academia.edu/Documents/in/Epigenetics"},{"id":28969,"name":"History and philosophy of science (History)","url":"https://www.academia.edu/Documents/in/History_and_philosophy_of_science_History_"},{"id":57139,"name":"History of genetics","url":"https://www.academia.edu/Documents/in/History_of_genetics"},{"id":110388,"name":"Biopower and Biopolitics","url":"https://www.academia.edu/Documents/in/Biopower_and_Biopolitics"},{"id":170124,"name":"Evolutionism","url":"https://www.academia.edu/Documents/in/Evolutionism"},{"id":235417,"name":"Political Epistemology","url":"https://www.academia.edu/Documents/in/Political_Epistemology"},{"id":1266728,"name":"History and Philosophy of Science","url":"https://www.academia.edu/Documents/in/History_and_Philosophy_of_Science-21"},{"id":1744493,"name":"Science and Technology Studies","url":"https://www.academia.edu/Documents/in/Science_and_Technology_Studies"}],"urls":[{"id":8575859,"url":"http://ediesseonline.it/catalogo/fondamenti/l-epigenetica"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="36805264"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/36805264/The_dialectical_legacy_of_epigenetics"><img alt="Research paper thumbnail of The dialectical legacy of epigenetics" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/36805264/The_dialectical_legacy_of_epigenetics">The dialectical legacy of epigenetics</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In this article I recognise three major historical phases of epigenetics, the first initiated by ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In this article I recognise three major historical phases of epigenetics, the first initiated by Child, Needham and Waddington during the first half of last century, focused on a dialectical analysis of biological processes between the organisms and their environments. The second phase started with the Bellagio conferences organised by Waddington where general principles derived from quantum physics were used to establishing a global order underpinned by scientific, objective facts beyond ethical and moral judgments. In the third phase, started with the failure of the Human Genome Project, there isn’t any consensus on the operative and philosophical notion of nature – i.e. the environmental context. Then, I highlight the necessity to reunify knowledge and moral within epigenetics.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="36805264"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="36805264"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 36805264; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=36805264]").text(description); $(".js-view-count[data-work-id=36805264]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 36805264; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='36805264']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 36805264, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=36805264]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":36805264,"title":"The dialectical legacy of epigenetics","translated_title":"","metadata":{"doi":"10.1075/cvs.13.12dab","abstract":"In this article I recognise three major historical phases of epigenetics, the first initiated by Child, Needham and Waddington during the first half of last century, focused on a dialectical analysis of biological processes between the organisms and their environments. 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Then, I highlight the necessity to reunify knowledge and moral within epigenetics.","internal_url":"https://www.academia.edu/36805264/The_dialectical_legacy_of_epigenetics","translated_internal_url":"","created_at":"2018-06-08T02:55:16.479-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"book","co_author_tags":[],"downloadable_attachments":[],"slug":"The_dialectical_legacy_of_epigenetics","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[],"research_interests":[{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics"},{"id":821,"name":"Philosophy of Science","url":"https://www.academia.edu/Documents/in/Philosophy_of_Science"},{"id":2513,"name":"Molecular Biology","url":"https://www.academia.edu/Documents/in/Molecular_Biology"},{"id":3723,"name":"History of Science","url":"https://www.academia.edu/Documents/in/History_of_Science"},{"id":3939,"name":"History and Philosophy of Biology","url":"https://www.academia.edu/Documents/in/History_and_Philosophy_of_Biology"},{"id":13075,"name":"History of Biology","url":"https://www.academia.edu/Documents/in/History_of_Biology"},{"id":22404,"name":"Epigenetics","url":"https://www.academia.edu/Documents/in/Epigenetics"},{"id":57139,"name":"History of genetics","url":"https://www.academia.edu/Documents/in/History_of_genetics"},{"id":60791,"name":"Research Policy","url":"https://www.academia.edu/Documents/in/Research_Policy"},{"id":136957,"name":"Science and Society","url":"https://www.academia.edu/Documents/in/Science_and_Society"},{"id":235417,"name":"Political Epistemology","url":"https://www.academia.edu/Documents/in/Political_Epistemology"},{"id":364937,"name":"Social Values","url":"https://www.academia.edu/Documents/in/Social_Values"},{"id":1323885,"name":"Epistemic Values","url":"https://www.academia.edu/Documents/in/Epistemic_Values"},{"id":1744493,"name":"Science and Technology Studies","url":"https://www.academia.edu/Documents/in/Science_and_Technology_Studies"}],"urls":[{"id":8516904,"url":"https://benjamins.com/catalog/cvs.13.12dab"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="35025320"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/35025320/Il_consenso_informato_in_ambito_terapeutico_Tra_autonomia_del_paziente_e_medicina_difensiva"><img alt="Research paper thumbnail of Il consenso informato in ambito terapeutico. Tra autonomia del paziente e medicina difensiva" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/35025320/Il_consenso_informato_in_ambito_terapeutico_Tra_autonomia_del_paziente_e_medicina_difensiva">Il consenso informato in ambito terapeutico. Tra autonomia del paziente e medicina difensiva</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Il volume presenta il consenso informato alla luce del dibattitto filosofico e antropologico e ne...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Il volume presenta il consenso informato alla luce del dibattitto filosofico e antropologico e nel suo sviluppo storico e legale. Pensato inizialmente per proteggere i soggetti di ricerca dagli abusi dei medici, il consenso informato si è poi trasformato in dispositivo ideologico–liberale per contrastare il paternalismo medico e promuovere il diritto individuale all’autodeterminazione dei pazienti. L’opera mette in evidenza gli aspetti più deboli di un dispositivo etico–giuridico oramai centenario, ad esempio il suo uso in medicina difensiva, per stimolare riflessioni utili a ricontestualizzarlo con appropriatezza nell’ambito della cura dei pazienti e nello scenario più ampio dei diritti sociali.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="35025320"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="35025320"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 35025320; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=35025320]").text(description); $(".js-view-count[data-work-id=35025320]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 35025320; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='35025320']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 35025320, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=35025320]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":35025320,"title":"Il consenso informato in ambito terapeutico. 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Colmare il gap fra STS, storia e filosofia della scienza" class="work-thumbnail" src="https://attachments.academia-assets.com/61462391/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/41232150/Call_for_Paper_Epistemologia_politica_delle_controversie_scientifiche_expertise_e_post_verit%C3%A0_Colmare_il_gap_fra_STS_storia_e_filosofia_della_scienza">Call for Paper: Epistemologia politica delle controversie scientifiche, expertise e post-verità. Colmare il gap fra STS, storia e filosofia della scienza</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://univr.academia.edu/GerardoIenna">Gerardo Ienna</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">L'aperto dibattito a proposito della post-verità, l'ascesa di varie forme di populismo, il consen...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">L'aperto dibattito a proposito della post-verità, l'ascesa di varie forme di populismo, il consenso che viene riconosciuto a coloro che propongono alternative facts sono alcuni dei sintomi che hanno portato ad una crisi delle figure sociali e politiche degli esperti e delle istituzioni scientifiche. Se da un lato alcuni, come S. Fuller, hanno letto l'avvento della post-verità come l'istaurarsi di una democrazia epistemologica altri, come H. Collins, hanno denunciato responsabilità politiche e intellettuali degli STS per aver minato un rapporto tra scienza e società basato su fiducia e affidabilità. Epistemologia, sociologia e storia della scienza si misurano con questo fenomeno in modo interdisciplinare tentando di comprendere la crisi dell'expertise. L'epistemologia storica fornisce un framework per analizzare concetti e controversie tecnoscientifiche nei loro contesti storicamente e socialmente determinati. La social epistemology mobilita concetti come epistemic (dis)trust, epistemic (in)justice o epistemic ignorance per capire come reputazione e consenso epistemico si formano tramite processi di attribuzione di "fiducia" o "sfiducia" che generano forme di "giustizia" o "ingiustizia" epistemica". Tali approcci possono esser sintetizzati sotto la comune etichetta di Political Epistemology nel momento in cui vengono diretti a mettere in luce gli effetti politico-ideologici del sapere tecnoscientifico. L'integrazione di questi framework con quelli forniti dagli STS può avere un effetto chiarificatore nell'analisi della crisi dell'expertise. Proponiamo dunque di aprire un'arena per discutere delle possibili intersezioni fra STS, storia e filosofia della scienza. In particolar modo è nostro interesse misurare la political epistemology con la sociologia delle controversie tecnoscientifiche e con i suoi principi metodologici di "imparzialità" e "simmetria". Fra le strategie discorsive maggiormente utilizzare vi sono quelle basate sulla costruzione di opposizioni retoriche come: 1) la tensione riduzionista a polarizzare i dibattiti in cui la scienza viene opposta all'anti-scienza, oppure 2) la falsa rappresentazione a livello pubblico di ambiti o fatti scientifici come problematici, conflittuali o controversi. Queste strategie hanno sostenuto, tramite la comunicazione scientifica, la fortuna dei populismi al fine di creare egemonia culturale e relativo consenso epistemico. Dall'altro lato, un superamento di tali strategie comunicative è stato sviluppato, ad esempio, dalle comunità locali impegnate in conflitti ambientali per il diritto alla salute attraverso alleanze con esperti e attraverso la co-produzione di pratiche scientifiche politicamente informate. In questo panel vogliamo analizzare le retoriche usate nella comunicazione scientifica per sviluppare una riflessione strategica e politica sul rapporto tra scienza, tecnologia e società. Invitiamo dunque riflessioni che analizzino: 1) Le controversie relative alla formazione e trasformazione di concetti scientifici da un punto di vista storico-ad es. tramite l'epistemologia storica; 2) il rapporto tra valori sociali e valori epistemici relativamente ai processi di costruzione della (s)fiducia e (in)giustizia epistemica-ad es. tramite political epistemology e social epistemology; 3) questioni metodologiche relative agli STS e la loro collocazione politica e sociale con un focus relativo ai conflitti sociali, relative controversie tecnoscientifiche e possibili strategie risolutive.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8ef8bd1621723f2884a5ddcae8f8414d" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":61462391,"asset_id":41232150,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/61462391/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="41232150"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="41232150"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 41232150; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=41232150]").text(description); $(".js-view-count[data-work-id=41232150]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 41232150; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='41232150']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 41232150, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8ef8bd1621723f2884a5ddcae8f8414d" } } $('.js-work-strip[data-work-id=41232150]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":41232150,"title":"Call for Paper: Epistemologia politica delle controversie scientifiche, expertise e post-verità. Colmare il gap fra STS, storia e filosofia della scienza","translated_title":"","metadata":{"abstract":"L'aperto dibattito a proposito della post-verità, l'ascesa di varie forme di populismo, il consenso che viene riconosciuto a coloro che propongono alternative facts sono alcuni dei sintomi che hanno portato ad una crisi delle figure sociali e politiche degli esperti e delle istituzioni scientifiche. Se da un lato alcuni, come S. Fuller, hanno letto l'avvento della post-verità come l'istaurarsi di una democrazia epistemologica altri, come H. Collins, hanno denunciato responsabilità politiche e intellettuali degli STS per aver minato un rapporto tra scienza e società basato su fiducia e affidabilità. Epistemologia, sociologia e storia della scienza si misurano con questo fenomeno in modo interdisciplinare tentando di comprendere la crisi dell'expertise. L'epistemologia storica fornisce un framework per analizzare concetti e controversie tecnoscientifiche nei loro contesti storicamente e socialmente determinati. La social epistemology mobilita concetti come epistemic (dis)trust, epistemic (in)justice o epistemic ignorance per capire come reputazione e consenso epistemico si formano tramite processi di attribuzione di \"fiducia\" o \"sfiducia\" che generano forme di \"giustizia\" o \"ingiustizia\" epistemica\". Tali approcci possono esser sintetizzati sotto la comune etichetta di Political Epistemology nel momento in cui vengono diretti a mettere in luce gli effetti politico-ideologici del sapere tecnoscientifico. L'integrazione di questi framework con quelli forniti dagli STS può avere un effetto chiarificatore nell'analisi della crisi dell'expertise. Proponiamo dunque di aprire un'arena per discutere delle possibili intersezioni fra STS, storia e filosofia della scienza. In particolar modo è nostro interesse misurare la political epistemology con la sociologia delle controversie tecnoscientifiche e con i suoi principi metodologici di \"imparzialità\" e \"simmetria\". Fra le strategie discorsive maggiormente utilizzare vi sono quelle basate sulla costruzione di opposizioni retoriche come: 1) la tensione riduzionista a polarizzare i dibattiti in cui la scienza viene opposta all'anti-scienza, oppure 2) la falsa rappresentazione a livello pubblico di ambiti o fatti scientifici come problematici, conflittuali o controversi. Queste strategie hanno sostenuto, tramite la comunicazione scientifica, la fortuna dei populismi al fine di creare egemonia culturale e relativo consenso epistemico. Dall'altro lato, un superamento di tali strategie comunicative è stato sviluppato, ad esempio, dalle comunità locali impegnate in conflitti ambientali per il diritto alla salute attraverso alleanze con esperti e attraverso la co-produzione di pratiche scientifiche politicamente informate. In questo panel vogliamo analizzare le retoriche usate nella comunicazione scientifica per sviluppare una riflessione strategica e politica sul rapporto tra scienza, tecnologia e società. Invitiamo dunque riflessioni che analizzino: 1) Le controversie relative alla formazione e trasformazione di concetti scientifici da un punto di vista storico-ad es. tramite l'epistemologia storica; 2) il rapporto tra valori sociali e valori epistemici relativamente ai processi di costruzione della (s)fiducia e (in)giustizia epistemica-ad es. tramite political epistemology e social epistemology; 3) questioni metodologiche relative agli STS e la loro collocazione politica e sociale con un focus relativo ai conflitti sociali, relative controversie tecnoscientifiche e possibili strategie risolutive."},"translated_abstract":"L'aperto dibattito a proposito della post-verità, l'ascesa di varie forme di populismo, il consenso che viene riconosciuto a coloro che propongono alternative facts sono alcuni dei sintomi che hanno portato ad una crisi delle figure sociali e politiche degli esperti e delle istituzioni scientifiche. Se da un lato alcuni, come S. Fuller, hanno letto l'avvento della post-verità come l'istaurarsi di una democrazia epistemologica altri, come H. Collins, hanno denunciato responsabilità politiche e intellettuali degli STS per aver minato un rapporto tra scienza e società basato su fiducia e affidabilità. Epistemologia, sociologia e storia della scienza si misurano con questo fenomeno in modo interdisciplinare tentando di comprendere la crisi dell'expertise. L'epistemologia storica fornisce un framework per analizzare concetti e controversie tecnoscientifiche nei loro contesti storicamente e socialmente determinati. La social epistemology mobilita concetti come epistemic (dis)trust, epistemic (in)justice o epistemic ignorance per capire come reputazione e consenso epistemico si formano tramite processi di attribuzione di \"fiducia\" o \"sfiducia\" che generano forme di \"giustizia\" o \"ingiustizia\" epistemica\". Tali approcci possono esser sintetizzati sotto la comune etichetta di Political Epistemology nel momento in cui vengono diretti a mettere in luce gli effetti politico-ideologici del sapere tecnoscientifico. L'integrazione di questi framework con quelli forniti dagli STS può avere un effetto chiarificatore nell'analisi della crisi dell'expertise. Proponiamo dunque di aprire un'arena per discutere delle possibili intersezioni fra STS, storia e filosofia della scienza. In particolar modo è nostro interesse misurare la political epistemology con la sociologia delle controversie tecnoscientifiche e con i suoi principi metodologici di \"imparzialità\" e \"simmetria\". Fra le strategie discorsive maggiormente utilizzare vi sono quelle basate sulla costruzione di opposizioni retoriche come: 1) la tensione riduzionista a polarizzare i dibattiti in cui la scienza viene opposta all'anti-scienza, oppure 2) la falsa rappresentazione a livello pubblico di ambiti o fatti scientifici come problematici, conflittuali o controversi. Queste strategie hanno sostenuto, tramite la comunicazione scientifica, la fortuna dei populismi al fine di creare egemonia culturale e relativo consenso epistemico. Dall'altro lato, un superamento di tali strategie comunicative è stato sviluppato, ad esempio, dalle comunità locali impegnate in conflitti ambientali per il diritto alla salute attraverso alleanze con esperti e attraverso la co-produzione di pratiche scientifiche politicamente informate. In questo panel vogliamo analizzare le retoriche usate nella comunicazione scientifica per sviluppare una riflessione strategica e politica sul rapporto tra scienza, tecnologia e società. Invitiamo dunque riflessioni che analizzino: 1) Le controversie relative alla formazione e trasformazione di concetti scientifici da un punto di vista storico-ad es. tramite l'epistemologia storica; 2) il rapporto tra valori sociali e valori epistemici relativamente ai processi di costruzione della (s)fiducia e (in)giustizia epistemica-ad es. tramite political epistemology e social epistemology; 3) questioni metodologiche relative agli STS e la loro collocazione politica e sociale con un focus relativo ai conflitti sociali, relative controversie tecnoscientifiche e possibili strategie risolutive.","internal_url":"https://www.academia.edu/41232150/Call_for_Paper_Epistemologia_politica_delle_controversie_scientifiche_expertise_e_post_verit%C3%A0_Colmare_il_gap_fra_STS_storia_e_filosofia_della_scienza","translated_internal_url":"","created_at":"2019-12-09T02:17:54.466-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1034863,"coauthors_can_edit":true,"document_type":"other","co_author_tags":[{"id":33376627,"work_id":41232150,"tagging_user_id":1034863,"tagged_user_id":1231121,"co_author_invite_id":null,"email":"f***o@gmail.com","affiliation":"Università degli Studi di Scienze Gastronomiche di Pollenzo","display_order":1,"name":"Flavio D'Abramo","title":"Call for Paper: Epistemologia politica delle controversie scientifiche, expertise e post-verità. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="10862177" id="news"><div class="js-work-strip profile--work_container" data-work-id="44831804"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/44831804/Video_Diplomacy_in_the_Time_of_Cholera_https_www_mpiwg_berlin_mpg_de_video_diplomacy_time_cholera"><img alt="Research paper thumbnail of Video: Diplomacy in the Time of Cholera https://www.mpiwg-berlin.mpg.de/video/diplomacy-time-cholera" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/44831804/Video_Diplomacy_in_the_Time_of_Cholera_https_www_mpiwg_berlin_mpg_de_video_diplomacy_time_cholera">Video: Diplomacy in the Time of Cholera https://www.mpiwg-berlin.mpg.de/video/diplomacy-time-cholera</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://uni-erlangen.academia.edu/MariaRentetzi">Maria Rentetzi</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a></span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The year 2020 has witnessed the most devastating pandemic in the past 100 years. At the time of w...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The year 2020 has witnessed the most devastating pandemic in the past 100 years. At the time of writing more than 70 million people globally have been infected; the death toll is over one and a half million. The social, political, and economic impact of the pandemic has been tremendous, and its longer-term consequences are yet uncertain. Local governments and health international organizations dealt with and continue to deal with this unprecedented situation in various ways. Despite national differences in responses, the pandemic exposed in critical ways the intermingling of scientific and diplomatic matters. Moreover, it resulted in widespread criticism of the World Health Organization’s (WHO) handling of the crisis.<br /><br />The history of science provides a unique perspective to investigate the roots of this inseparable connection between science and diplomacy in international responses to the pandemic. In this video, produced by scholars at the Max Planck Institute for History of Science (MPIWG) and with the support of an ERC Consolidator Grant (grant agreement No770548, HRP-IAEA) at the FAU Erlangen-Nuremberg, we unfold how diplomacy has become vital for global health, and how the WHO became a key player in health diplomacy.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="44831804"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="44831804"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 44831804; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=44831804]").text(description); $(".js-view-count[data-work-id=44831804]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 44831804; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='44831804']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 44831804, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=44831804]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":44831804,"title":"Video: Diplomacy in the Time of Cholera\r\nhttps://www.mpiwg-berlin.mpg.de/video/diplomacy-time-cholera","translated_title":"","metadata":{"abstract":"The year 2020 has witnessed the most devastating pandemic in the past 100 years. At the time of writing more than 70 million people globally have been infected; the death toll is over one and a half million. The social, political, and economic impact of the pandemic has been tremendous, and its longer-term consequences are yet uncertain. Local governments and health international organizations dealt with and continue to deal with this unprecedented situation in various ways. Despite national differences in responses, the pandemic exposed in critical ways the intermingling of scientific and diplomatic matters. Moreover, it resulted in widespread criticism of the World Health Organization’s (WHO) handling of the crisis.\n\nThe history of science provides a unique perspective to investigate the roots of this inseparable connection between science and diplomacy in international responses to the pandemic. In this video, produced by scholars at the Max Planck Institute for History of Science (MPIWG) and with the support of an ERC Consolidator Grant (grant agreement No770548, HRP-IAEA) at the FAU Erlangen-Nuremberg, we unfold how diplomacy has become vital for global health, and how the WHO became a key player in health diplomacy.","publication_date":{"day":null,"month":null,"year":2020,"errors":{}}},"translated_abstract":"The year 2020 has witnessed the most devastating pandemic in the past 100 years. At the time of writing more than 70 million people globally have been infected; the death toll is over one and a half million. The social, political, and economic impact of the pandemic has been tremendous, and its longer-term consequences are yet uncertain. Local governments and health international organizations dealt with and continue to deal with this unprecedented situation in various ways. Despite national differences in responses, the pandemic exposed in critical ways the intermingling of scientific and diplomatic matters. Moreover, it resulted in widespread criticism of the World Health Organization’s (WHO) handling of the crisis.\n\nThe history of science provides a unique perspective to investigate the roots of this inseparable connection between science and diplomacy in international responses to the pandemic. In this video, produced by scholars at the Max Planck Institute for History of Science (MPIWG) and with the support of an ERC Consolidator Grant (grant agreement No770548, HRP-IAEA) at the FAU Erlangen-Nuremberg, we unfold how diplomacy has become vital for global health, and how the WHO became a key player in health diplomacy.","internal_url":"https://www.academia.edu/44831804/Video_Diplomacy_in_the_Time_of_Cholera_https_www_mpiwg_berlin_mpg_de_video_diplomacy_time_cholera","translated_internal_url":"","created_at":"2021-01-04T06:35:35.774-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":5743119,"coauthors_can_edit":true,"document_type":"other","co_author_tags":[{"id":36123378,"work_id":44831804,"tagging_user_id":5743119,"tagged_user_id":1231121,"co_author_invite_id":null,"email":"f***o@gmail.com","affiliation":"Università degli Studi di Scienze Gastronomiche di Pollenzo","display_order":0,"name":"Flavio D'Abramo","title":"Video: Diplomacy in the Time of Cholera\r\nhttps://www.mpiwg-berlin.mpg.de/video/diplomacy-time-cholera"},{"id":36123379,"work_id":44831804,"tagging_user_id":5743119,"tagged_user_id":1106609,"co_author_invite_id":null,"email":"r***i@mpiwg-berlin.mpg.de","affiliation":"Max Planck Institute for the History of Science","display_order":4194304,"name":"Roberto Lalli","title":"Video: Diplomacy in the Time of Cholera\r\nhttps://www.mpiwg-berlin.mpg.de/video/diplomacy-time-cholera"}],"downloadable_attachments":[],"slug":"Video_Diplomacy_in_the_Time_of_Cholera_https_www_mpiwg_berlin_mpg_de_video_diplomacy_time_cholera","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":5743119,"first_name":"Maria","middle_initials":null,"last_name":"Rentetzi","page_name":"MariaRentetzi","domain_name":"uni-erlangen","created_at":"2013-09-24T22:43:19.334-07:00","display_name":"Maria Rentetzi","url":"https://uni-erlangen.academia.edu/MariaRentetzi"},"attachments":[],"research_interests":[{"id":128,"name":"History","url":"https://www.academia.edu/Documents/in/History"},{"id":696,"name":"Gender Studies","url":"https://www.academia.edu/Documents/in/Gender_Studies"},{"id":3723,"name":"History of Science","url":"https://www.academia.edu/Documents/in/History_of_Science"},{"id":71125,"name":"Political Science and Diplomacy","url":"https://www.academia.edu/Documents/in/Political_Science_and_Diplomacy"},{"id":475012,"name":"Science Diplomacy","url":"https://www.academia.edu/Documents/in/Science_Diplomacy"},{"id":521881,"name":"World Health Organization","url":"https://www.academia.edu/Documents/in/World_Health_Organization"},{"id":1744493,"name":"Science and Technology Studies","url":"https://www.academia.edu/Documents/in/Science_and_Technology_Studies"}],"urls":[{"id":9181783,"url":"https://www.mpiwg-berlin.mpg.de/video/diplomacy-time-cholera"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="11288546" id="papersandbookchapters"><div class="js-work-strip profile--work_container" data-work-id="82007099"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/82007099/Expertise_ed_epistemologia_politica_Introduzione"><img alt="Research paper thumbnail of Expertise ed epistemologia politica - Introduzione" class="work-thumbnail" src="https://attachments.academia-assets.com/87852117/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/82007099/Expertise_ed_epistemologia_politica_Introduzione">Expertise ed epistemologia politica - Introduzione</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a> and <a class="" data-click-track="profile-work-strip-authors" href="https://univr.academia.edu/GerardoIenna">Gerardo Ienna</a></span></div><div class="wp-workCard_item"><span>Expertise ed epistemologia politica</span><span>, 2022</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Questo volume si pone l’obiettivo di rimettere al centro dell’attenzione una riflessione di cara...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Questo volume si pone l’obiettivo di rimettere al centro dell’attenzione una <br />riflessione di carattere politico sullo statuto dell’expertise nella società contemporanea. L’attuale dibattito all’interno degli studi sociali sulla scienza sembra essersi consolidato attorno a delle polarità oppositive apparentemente insormontabili: da un lato il post-modernismo relativista, risultato di un’estremizzazione del costruttivismo sociale; dall’altro il veritismo ingenuo, come adozione irriflessa delle posizioni (neo)positiviste. <br />In questo contesto, la figura sociale dell’esperto si trova al centro del dibattito epistemologico e politico. Cosa significa essere esperti di qualcosa? Qual è la loro funzione sociale? Come avviene il processo di attribuzione della fiducia e della sfiducia epistemologiche? Quali forme di neutralità e nonneutralità dovremmo adottare nel valutare il prodotto di una riflessione esperta? Quali metodi e prospettive abbiamo per studiare l’expertise? Per i curatori del volume è necessario aprire una tavola di discussione interdisciplinare su questi argomenti, lanciando in Italia un dibatto che all’estero è invece già largamente prolifico.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b1dea901de3f1e51bdd7aa632102affa" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":87852117,"asset_id":82007099,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/87852117/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="82007099"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="82007099"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 82007099; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=82007099]").text(description); $(".js-view-count[data-work-id=82007099]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 82007099; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='82007099']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 82007099, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b1dea901de3f1e51bdd7aa632102affa" } } $('.js-work-strip[data-work-id=82007099]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":82007099,"title":"Expertise ed epistemologia politica - Introduzione","translated_title":"","metadata":{"abstract":"Questo volume si pone l’obiettivo di rimettere al centro dell’attenzione una\r\nriflessione di carattere politico sullo statuto dell’expertise nella società contemporanea. L’attuale dibattito all’interno degli studi sociali sulla scienza sembra essersi consolidato attorno a delle polarità oppositive apparentemente insormontabili: da un lato il post-modernismo relativista, risultato di un’estremizzazione del costruttivismo sociale; dall’altro il veritismo ingenuo, come adozione irriflessa delle posizioni (neo)positiviste.\r\nIn questo contesto, la figura sociale dell’esperto si trova al centro del dibattito epistemologico e politico. Cosa significa essere esperti di qualcosa? Qual è la loro funzione sociale? Come avviene il processo di attribuzione della fiducia e della sfiducia epistemologiche? Quali forme di neutralità e nonneutralità dovremmo adottare nel valutare il prodotto di una riflessione esperta? Quali metodi e prospettive abbiamo per studiare l’expertise? Per i curatori del volume è necessario aprire una tavola di discussione interdisciplinare su questi argomenti, lanciando in Italia un dibatto che all’estero è invece già largamente prolifico.","publication_date":{"day":null,"month":null,"year":2022,"errors":{}},"publication_name":"Expertise ed epistemologia politica"},"translated_abstract":"Questo volume si pone l’obiettivo di rimettere al centro dell’attenzione una\r\nriflessione di carattere politico sullo statuto dell’expertise nella società contemporanea. L’attuale dibattito all’interno degli studi sociali sulla scienza sembra essersi consolidato attorno a delle polarità oppositive apparentemente insormontabili: da un lato il post-modernismo relativista, risultato di un’estremizzazione del costruttivismo sociale; dall’altro il veritismo ingenuo, come adozione irriflessa delle posizioni (neo)positiviste.\r\nIn questo contesto, la figura sociale dell’esperto si trova al centro del dibattito epistemologico e politico. Cosa significa essere esperti di qualcosa? Qual è la loro funzione sociale? Come avviene il processo di attribuzione della fiducia e della sfiducia epistemologiche? Quali forme di neutralità e nonneutralità dovremmo adottare nel valutare il prodotto di una riflessione esperta? Quali metodi e prospettive abbiamo per studiare l’expertise? Per i curatori del volume è necessario aprire una tavola di discussione interdisciplinare su questi argomenti, lanciando in Italia un dibatto che all’estero è invece già largamente prolifico.","internal_url":"https://www.academia.edu/82007099/Expertise_ed_epistemologia_politica_Introduzione","translated_internal_url":"","created_at":"2022-06-21T13:25:05.574-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":1231121,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[{"id":38425886,"work_id":82007099,"tagging_user_id":1231121,"tagged_user_id":1034863,"co_author_invite_id":null,"email":"g***a@gmail.com","affiliation":"Università di Verona","display_order":1,"name":"Gerardo Ienna","title":"Expertise ed epistemologia politica - Introduzione"},{"id":38425887,"work_id":82007099,"tagging_user_id":1231121,"tagged_user_id":875169,"co_author_invite_id":null,"email":"m***t@yahoo.it","affiliation":"Università di Verona","display_order":2,"name":"Massimiliano Badino","title":"Expertise ed epistemologia politica - Introduzione"}],"downloadable_attachments":[{"id":87852117,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/87852117/thumbnails/1.jpg","file_name":"Introduzione_00.pdf","download_url":"https://www.academia.edu/attachments/87852117/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Expertise_ed_epistemologia_politica_Intr.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/87852117/Introduzione_00-libre.pdf?1655844803=\u0026response-content-disposition=attachment%3B+filename%3DExpertise_ed_epistemologia_politica_Intr.pdf\u0026Expires=1732809784\u0026Signature=TwknZHsgUgdaTqVSc4Fu8V9M0Suiu77Nm~JLh-A~n95q95PR6V1a8yh8DNrRu-I7xFkLUuMRxjc03s5niMN94n4M7UpcsMZbFcsEMz~XNvSYqw69-bFNxQZEIyYHi7cJs5aMAFD6HxvyeClxfHbvaaoTrZsOqK8icn0FIftBV5nY3TePdMS4ZXPKS2u1aLD8wn~lLPKsHLLFjd9ze3ykNw0BQ1KAcv9a0AFXgq~GbISOSp1JjApHJrru477ZQlQSRT7fv5Oy~d6RIXrXjb22VlUzznkzrekdZCH7P13XV9lrQxla6hTueEi5bRigv-ZvrVCCK30yt3zLEsM3U53FpQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Expertise_ed_epistemologia_politica_Introduzione","translated_slug":"","page_count":33,"language":"it","content_type":"Work","owner":{"id":1231121,"first_name":"Flavio","middle_initials":null,"last_name":"D'Abramo","page_name":"FlavioDAbramo","domain_name":"unisg-it","created_at":"2012-02-21T19:21:32.062-08:00","display_name":"Flavio D'Abramo","url":"https://unisg-it.academia.edu/FlavioDAbramo"},"attachments":[{"id":87852117,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/87852117/thumbnails/1.jpg","file_name":"Introduzione_00.pdf","download_url":"https://www.academia.edu/attachments/87852117/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Expertise_ed_epistemologia_politica_Intr.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/87852117/Introduzione_00-libre.pdf?1655844803=\u0026response-content-disposition=attachment%3B+filename%3DExpertise_ed_epistemologia_politica_Intr.pdf\u0026Expires=1732809784\u0026Signature=TwknZHsgUgdaTqVSc4Fu8V9M0Suiu77Nm~JLh-A~n95q95PR6V1a8yh8DNrRu-I7xFkLUuMRxjc03s5niMN94n4M7UpcsMZbFcsEMz~XNvSYqw69-bFNxQZEIyYHi7cJs5aMAFD6HxvyeClxfHbvaaoTrZsOqK8icn0FIftBV5nY3TePdMS4ZXPKS2u1aLD8wn~lLPKsHLLFjd9ze3ykNw0BQ1KAcv9a0AFXgq~GbISOSp1JjApHJrru477ZQlQSRT7fv5Oy~d6RIXrXjb22VlUzznkzrekdZCH7P13XV9lrQxla6hTueEi5bRigv-ZvrVCCK30yt3zLEsM3U53FpQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":815,"name":"Epistemology","url":"https://www.academia.edu/Documents/in/Epistemology"},{"id":3723,"name":"History of Science","url":"https://www.academia.edu/Documents/in/History_of_Science"},{"id":16091,"name":"Sociology of Science","url":"https://www.academia.edu/Documents/in/Sociology_of_Science"},{"id":235417,"name":"Political Epistemology","url":"https://www.academia.edu/Documents/in/Political_Epistemology"},{"id":1744493,"name":"Science and Technology Studies","url":"https://www.academia.edu/Documents/in/Science_and_Technology_Studies"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="49024837"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/49024837/Political_Epistemology_of_Pandemic_Management"><img alt="Research paper thumbnail of Political Epistemology of Pandemic Management" class="work-thumbnail" src="https://attachments.academia-assets.com/67409725/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/49024837/Political_Epistemology_of_Pandemic_Management">Political Epistemology of Pandemic Management</a></div><div class="wp-workCard_item wp-workCard--coauthors"><span>by </span><span><a class="" data-click-track="profile-work-strip-authors" href="https://univ-tlse2.academia.edu/CharlesWolfe">Charles Wolfe</a>, <a class="" data-click-track="profile-work-strip-authors" href="https://unisg-it.academia.edu/FlavioDAbramo">Flavio D'Abramo</a>, and <a class="" data-click-track="profile-work-strip-authors" href="https://univr.academia.edu/GerardoIenna">Gerardo Ienna</a></span></div><div class="wp-workCard_item"><span>MeFiSto</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Today, claims about the contiguity of health management and societal organization bring biopoliti...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Today, claims about the contiguity of health management and societal organization bring biopolitical concerns to the forefront. This essay offers historical-political insights on the covid-19 pandemic, which are particularly urgent, as both the temporal and the cultural-political dimensions have been insufficiently considered in current debates. After introducing our specific political-epistemological approach, we delve into the entanglements of medical expertise, economic interests, surveillance politics, and diplomatic relations in the past in order to shed light on the present. Additionally, we address the limitations of Italian theory's biopolitica, namely its idle radicalization of critical views on medical politics inspired by French épistémologie historique. We conclude with a call to scientists' responsibility in consideration of the societal embedment of their activity. Yet, the task of an emancipated science is not only in their hands but depends on our collective capacity to organically connect their work to the renewal of the body politics at large.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="efa9b29af4f3a2bd684f9791c56797d7" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":67409725,"asset_id":49024837,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/67409725/download_file?st=MTczMjgyOTU0OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="49024837"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="49024837"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 49024837; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=49024837]").text(description); $(".js-view-count[data-work-id=49024837]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 49024837; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='49024837']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 49024837, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "efa9b29af4f3a2bd684f9791c56797d7" } } $('.js-work-strip[data-work-id=49024837]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":49024837,"title":"Political Epistemology of Pandemic Management","translated_title":"","metadata":{"abstract":"Today, claims about the contiguity of health management and societal organization bring biopolitical concerns to the forefront. 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