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<!DOCTYPE html> <html lang="en" class="no-js"> <head> <meta charset="UTF-8"> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <meta name="applicable-device" content="pc,mobile"> <meta name="viewport" content="width=device-width, initial-scale=1"> <meta name="robots" content="max-image-preview:large"> <meta name="access" content="Yes"> <meta name="360-site-verification" content="1268d79b5e96aecf3ff2a7dac04ad990" /> <title>Transmission of SARS-Cov-2 and other enveloped viruses to the environment through protective gear: a brief review | Euro-Mediterranean Journal for Environmental Integration</title> <meta name="twitter:site" content="@SpringerLink"/> <meta name="twitter:card" content="summary_large_image"/> <meta name="twitter:image:alt" content="Content cover image"/> <meta name="twitter:title" content="Transmission of SARS-Cov-2 and other enveloped viruses to the environment through protective gear: a brief review"/> <meta name="twitter:description" content="Euro-Mediterranean Journal for Environmental Integration - Over the past two decades, several deadly viral epidemics have emerged, which have placed humanity in danger. Previous investigations have..."/> <meta name="twitter:image" content="https://static-content.springer.com/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig1_HTML.png"/> <meta name="journal_id" content="41207"/> <meta name="dc.title" content="Transmission of SARS-Cov-2 and other enveloped viruses to the environment through protective gear: a brief review"/> <meta name="dc.source" content="Euro-Mediterranean Journal for Environmental Integration 2021 6:2"/> <meta name="dc.format" content="text/html"/> <meta name="dc.publisher" content="Springer"/> <meta name="dc.date" content="2021-04-07"/> <meta name="dc.type" content="OriginalPaper"/> <meta name="dc.language" content="En"/> <meta name="dc.copyright" content="2021 The Author(s)"/> <meta name="dc.rights" content="2021 The Author(s)"/> <meta name="dc.rightsAgent" content="journalpermissions@springernature.com"/> <meta name="dc.description" content="Over the past two decades, several deadly viral epidemics have emerged, which have placed humanity in danger. Previous investigations have suggested that viral diseases can spread through contaminants or contaminated surfaces. The transmission of viruses via polluted surfaces relies upon their capacity to maintain their infectivity while they are in the environment. Here, a range of materials that are widely used to manufacture personal protective equipment (PPE) are summarized, as these offer effective disinfection solutions and are the environmental variables that influence virus survival. Infection modes and prevention as well as disinfection and PPE disposal strategies are discussed. A coronavirus-like enveloped virus can live in the environment after being discharged from a host organism until it infects another healthy individual. Transmission of enveloped viruses such as SARS-CoV-2 can occur even without direct contact, although detailed knowledge of airborne routes and other indirect transmission paths is still lacking. Ground transmission of viruses is also possible via wastewater discharges. While enveloped viruses can contaminate potable water and wastewater through human excretions such as feces and droplets, careless PPE disposal can also lead to their transmission into our environment. This paper also highlights the possibility that viruses can be transmitted into the environment from PPE kits used by healthcare and emergency service personnel. A simulation-based approach was developed to understand the transport mechanism for coronavirus and similar enveloped viruses in the environment through porous media, and preliminary results from this model are presented here. Those results indicate that viruses can move through porous soil and eventually contaminate groundwater. This paper therefore underlines the importance of proper PPE disposal by healthcare workers in the Mediterranean region and around the world."/> <meta name="prism.issn" content="2365-7448"/> <meta name="prism.publicationName" content="Euro-Mediterranean Journal for Environmental Integration"/> <meta name="prism.publicationDate" content="2021-04-07"/> <meta name="prism.volume" content="6"/> <meta name="prism.number" content="2"/> <meta name="prism.section" content="OriginalPaper"/> <meta name="prism.startingPage" content="1"/> <meta name="prism.endingPage" content="13"/> <meta name="prism.copyright" content="2021 The Author(s)"/> <meta name="prism.rightsAgent" content="journalpermissions@springernature.com"/> <meta name="prism.url" content="https://link.springer.com/article/10.1007/s41207-021-00251-w"/> <meta name="prism.doi" content="doi:10.1007/s41207-021-00251-w"/> <meta name="citation_pdf_url" content="https://link.springer.com/content/pdf/10.1007/s41207-021-00251-w.pdf"/> <meta name="citation_fulltext_html_url" content="https://link.springer.com/article/10.1007/s41207-021-00251-w"/> <meta name="citation_journal_title" content="Euro-Mediterranean Journal for Environmental Integration"/> <meta name="citation_journal_abbrev" content="Euro-Mediterr J Environ Integr"/> <meta name="citation_publisher" content="Springer International Publishing"/> <meta name="citation_issn" content="2365-7448"/> <meta name="citation_title" content="Transmission of SARS-Cov-2 and other enveloped viruses to the environment through protective gear: a brief review"/> <meta name="citation_volume" content="6"/> <meta name="citation_issue" content="2"/> <meta name="citation_publication_date" content="2021/09"/> <meta name="citation_online_date" content="2021/04/07"/> <meta name="citation_firstpage" content="1"/> <meta name="citation_lastpage" content="13"/> <meta name="citation_article_type" content="Original Paper"/> <meta name="citation_fulltext_world_readable" content=""/> <meta name="citation_language" content="en"/> <meta name="dc.identifier" content="doi:10.1007/s41207-021-00251-w"/> <meta name="DOI" content="10.1007/s41207-021-00251-w"/> <meta name="size" content="139496"/> <meta name="citation_doi" content="10.1007/s41207-021-00251-w"/> <meta name="citation_springer_api_url" content="http://api.springer.com/xmldata/jats?q=doi:10.1007/s41207-021-00251-w&api_key="/> <meta name="description" content="Over the past two decades, several deadly viral epidemics have emerged, which have placed humanity in danger. Previous investigations have suggested that v"/> <meta name="dc.creator" content="Petrosino, Francesco"/> <meta name="dc.creator" content="Mukherjee, Debolina"/> <meta name="dc.creator" content="Coppola, Gerardo"/> <meta name="dc.creator" content="Gaudio, Maria Teresa"/> <meta name="dc.creator" content="Curcio, Stefano"/> <meta name="dc.creator" content="Calabro, Vincenza"/> <meta name="dc.creator" content="Marra, Francesco"/> <meta name="dc.creator" content="Bhattacharya, Prosun"/> <meta name="dc.creator" content="Pal, Umapada"/> <meta name="dc.creator" content="Khélifi, Nabil"/> <meta name="dc.creator" content="Chakraborty, Sudip"/> <meta name="dc.subject" content="Environmental Science and Engineering"/> <meta name="dc.subject" content="Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution"/> <meta name="dc.subject" content="Environmental Management"/> <meta name="dc.subject" content="Atmospheric Protection/Air Quality Control/Air Pollution"/> <meta name="dc.subject" content="Waste Management/Waste Technology"/> <meta name="dc.subject" content="Environmental Chemistry"/> <meta name="citation_reference" content="citation_journal_title=Earth Syst Environ; citation_title=Spatiotemporal assessment of COVID-19 spread over Oman using GIS techniques; citation_author=KM Al-Kindi, A Alkharusi, D Alshukaili; citation_volume=4; citation_publication_date=2020; citation_pages=797-811; citation_doi=10.1007/s41748-020-00194-2; citation_id=CR1"/> <meta name="citation_reference" content="Andersen BM (2019) Chap. 84: Personal protective equipment (PPE). 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Previous investigations have suggested that viral diseases can spread through contaminants or contaminated surfaces. The transmission of viruses via polluted surfaces relies upon their capacity to maintain their infectivity while they are in the environment. Here, a range of materials that are widely used to manufacture personal protective equipment (PPE) are summarized, as these offer effective disinfection solutions and are the environmental variables that influence virus survival. Infection modes and prevention as well as disinfection and PPE disposal strategies are discussed. A coronavirus-like enveloped virus can live in the environment after being discharged from a host organism until it infects another healthy individual. Transmission of enveloped viruses such as SARS-CoV-2 can occur even without direct contact, although detailed knowledge of airborne routes and other indirect transmission paths is still lacking. Ground transmission of viruses is also possible via wastewater discharges. While enveloped viruses can contaminate potable water and wastewater through human excretions such as feces and droplets, careless PPE disposal can also lead to their transmission into our environment. This paper also highlights the possibility that viruses can be transmitted into the environment from PPE kits used by healthcare and emergency service personnel. A simulation-based approach was developed to understand the transport mechanism for coronavirus and similar enveloped viruses in the environment through porous media, and preliminary results from this model are presented here. Those results indicate that viruses can move through porous soil and eventually contaminate groundwater. This paper therefore underlines the importance of proper PPE disposal by healthcare workers in the Mediterranean region and around the world."/> <meta property="og:image" content="https://static-content.springer.com/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig1_HTML.png"/> <meta name="format-detection" content="telephone=no"> <link rel="apple-touch-icon" sizes="180x180" href=/oscar-static/img/favicons/darwin/apple-touch-icon-92e819bf8a.png> <link rel="icon" type="image/png" sizes="192x192" href=/oscar-static/img/favicons/darwin/android-chrome-192x192-6f081ca7e5.png> <link rel="icon" type="image/png" sizes="32x32" href=/oscar-static/img/favicons/darwin/favicon-32x32-1435da3e82.png> <link rel="icon" type="image/png" sizes="16x16" href=/oscar-static/img/favicons/darwin/favicon-16x16-ed57f42bd2.png> <link rel="shortcut icon" data-test="shortcut-icon" href=/oscar-static/img/favicons/darwin/favicon-c6d59aafac.ico> <meta name="theme-color" content="#e6e6e6">   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Previous investigations have suggested that viral diseases can spread through contaminants or contaminated surfaces. The transmission of viruses via polluted surfaces relies upon their capacity to maintain their infectivity while they are in the environment. Here, a range of materials that are widely used to manufacture personal protective equipment (PPE) are summarized, as these offer effective disinfection solutions and are the environmental variables that influence virus survival. Infection modes and prevention as well as disinfection and PPE disposal strategies are discussed. A coronavirus-like enveloped virus can live in the environment after being discharged from a host organism until it infects another healthy individual. Transmission of enveloped viruses such as SARS-CoV-2 can occur even without direct contact, although detailed knowledge of airborne routes and other indirect transmission paths is still lacking. Ground transmission of viruses is also possible via wastewater discharges. While enveloped viruses can contaminate potable water and wastewater through human excretions such as feces and droplets, careless PPE disposal can also lead to their transmission into our environment. This paper also highlights the possibility that viruses can be transmitted into the environment from PPE kits used by healthcare and emergency service personnel. A simulation-based approach was developed to understand the transport mechanism for coronavirus and similar enveloped viruses in the environment through porous media, and preliminary results from this model are presented here. Those results indicate that viruses can move through porous soil and eventually contaminate groundwater. 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</div> </div> <div class="c-article-header"> <header> <ul class="c-article-author-list c-article-author-list--short" data-test="authors-list" data-component-authors-activator="authors-list"><li class="c-article-author-list__item"><a data-test="author-name" data-track="click" data-track-action="open author" data-track-label="link" href="#auth-Francesco-Petrosino-Aff1-Aff2" data-author-popup="auth-Francesco-Petrosino-Aff1-Aff2" data-author-search="Petrosino, Francesco">Francesco Petrosino</a><sup class="u-js-hide"><a href="#Aff1">1</a>,<a href="#Aff2">2</a></sup>, </li><li class="c-article-author-list__item"><a data-test="author-name" data-track="click" data-track-action="open author" data-track-label="link" href="#auth-Debolina-Mukherjee-Aff1" data-author-popup="auth-Debolina-Mukherjee-Aff1" data-author-search="Mukherjee, Debolina">Debolina Mukherjee</a><sup class="u-js-hide"><a href="#Aff1">1</a></sup>, </li><li class="c-article-author-list__item 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data-author-popup="auth-Stefano-Curcio-Aff1" data-author-search="Curcio, Stefano">Stefano Curcio</a><sup class="u-js-hide"><a href="#Aff1">1</a></sup>, </li><li class="c-article-author-list__item c-article-author-list__item--hide-small-screen"><a data-test="author-name" data-track="click" data-track-action="open author" data-track-label="link" href="#auth-Vincenza-Calabro-Aff1" data-author-popup="auth-Vincenza-Calabro-Aff1" data-author-search="Calabro, Vincenza">Vincenza Calabro</a><sup class="u-js-hide"><a href="#Aff1">1</a></sup>, </li><li class="c-article-author-list__item c-article-author-list__item--hide-small-screen"><a data-test="author-name" data-track="click" data-track-action="open author" data-track-label="link" href="#auth-Francesco-Marra-Aff2" data-author-popup="auth-Francesco-Marra-Aff2" data-author-search="Marra, Francesco">Francesco Marra</a><sup class="u-js-hide"><a href="#Aff2">2</a></sup>, </li><li class="c-article-author-list__item 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data-author-search="Khélifi, Nabil">Nabil Khélifi</a><sup class="u-js-hide"><a href="#Aff5">5</a></sup> & </li><li class="c-article-author-list__show-more" aria-label="Show all 11 authors for this article" title="Show all 11 authors for this article">…</li><li class="c-article-author-list__item"><a data-test="author-name" data-track="click" data-track-action="open author" data-track-label="link" href="#auth-Sudip-Chakraborty-Aff1" data-author-popup="auth-Sudip-Chakraborty-Aff1" data-author-search="Chakraborty, Sudip" data-corresp-id="c1">Sudip Chakraborty<svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-mail-medium"></use></svg></a><span class="u-js-hide"> <a class="js-orcid" href="http://orcid.org/0000-0002-1752-4682"><span class="u-visually-hidden">ORCID: </span>orcid.org/0000-0002-1752-4682</a></span><sup class="u-js-hide"><a href="#Aff1">1</a></sup> </li></ul><button aria-expanded="false" class="c-article-author-list__button"><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-down-medium"></use></svg><span>Show authors</span></button> <div data-test="article-metrics"> <ul class="app-article-metrics-bar u-list-reset"> <li class="app-article-metrics-bar__item"> <p class="app-article-metrics-bar__count"><svg class="u-icon app-article-metrics-bar__icon" width="24" height="24" aria-hidden="true" focusable="false"> <use xlink:href="#icon-eds-i-accesses-medium"></use> </svg>3791 <span class="app-article-metrics-bar__label">Accesses</span></p> </li> <li class="app-article-metrics-bar__item"> <p class="app-article-metrics-bar__count"><svg class="u-icon app-article-metrics-bar__icon" width="24" height="24" aria-hidden="true" focusable="false"> <use xlink:href="#icon-eds-i-citations-medium"></use> </svg>7 <span class="app-article-metrics-bar__label">Citations</span></p> </li> <li class="app-article-metrics-bar__item"> <p class="app-article-metrics-bar__count"><svg class="u-icon app-article-metrics-bar__icon" width="24" height="24" aria-hidden="true" focusable="false"> <use xlink:href="#icon-eds-i-altmetric-medium"></use> </svg>1 <span class="app-article-metrics-bar__label">Altmetric</span></p> </li> <li class="app-article-metrics-bar__item app-article-metrics-bar__item--metrics"> <p class="app-article-metrics-bar__details"><a href="/article/10.1007/s41207-021-00251-w/metrics" data-track="click" data-track-action="view metrics" data-track-label="link" rel="nofollow">Explore all metrics <svg class="u-icon app-article-metrics-bar__arrow-icon" width="24" height="24" aria-hidden="true" focusable="false"> <use xlink:href="#icon-eds-i-arrow-right-medium"></use> </svg></a></p> </li> </ul> </div> <div class="u-mt-32"> </div> </header> </div> <div data-article-body="true" data-track-component="article body" class="c-article-body"> <section aria-labelledby="Abs1" data-title="Abstract" lang="en"><div class="c-article-section" id="Abs1-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Abs1">Abstract</h2><div class="c-article-section__content" id="Abs1-content"><p>Over the past two decades, several deadly viral epidemics have emerged, which have placed humanity in danger. Previous investigations have suggested that viral diseases can spread through contaminants or contaminated surfaces. The transmission of viruses via polluted surfaces relies upon their capacity to maintain their infectivity while they are in the environment. Here, a range of materials that are widely used to manufacture personal protective equipment (PPE) are summarized, as these offer effective disinfection solutions and are the environmental variables that influence virus survival. Infection modes and prevention as well as disinfection and PPE disposal strategies are discussed. A coronavirus-like enveloped virus can live in the environment after being discharged from a host organism until it infects another healthy individual. Transmission of enveloped viruses such as SARS-CoV-2 can occur even without direct contact, although detailed knowledge of airborne routes and other indirect transmission paths is still lacking. Ground transmission of viruses is also possible via wastewater discharges. While enveloped viruses can contaminate potable water and wastewater through human excretions such as feces and droplets, careless PPE disposal can also lead to their transmission into our environment. This paper also highlights the possibility that viruses can be transmitted into the environment from PPE kits used by healthcare and emergency service personnel. A simulation-based approach was developed to understand the transport mechanism for coronavirus and similar enveloped viruses in the environment through porous media, and preliminary results from this model are presented here. Those results indicate that viruses can move through porous soil and eventually contaminate groundwater. This paper therefore underlines the importance of proper PPE disposal by healthcare workers in the Mediterranean region and around the world.</p></div></div></section> <div data-test="cobranding-download"> </div> <section aria-labelledby="inline-recommendations" data-title="Inline Recommendations" class="c-article-recommendations" data-track-component="inline-recommendations"> <h3 class="c-article-recommendations-title" id="inline-recommendations">Similar content being viewed by others</h3> <div class="c-article-recommendations-list"> <div class="c-article-recommendations-list__item"> <article class="c-article-recommendations-card" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-article-recommendations-card__img"><img src="https://media.springernature.com/w215h120/springer-static/image/art%3A10.1038%2Fs41598-022-20952-8/MediaObjects/41598_2022_20952_Fig1_HTML.png" loading="lazy" alt=""></div> <div class="c-article-recommendations-card__main"> <h3 class="c-article-recommendations-card__heading" itemprop="name headline"> <a class="c-article-recommendations-card__link" itemprop="url" href="https://link.springer.com/10.1038/s41598-022-20952-8?fromPaywallRec=false" data-track="select_recommendations_1" data-track-context="inline recommendations" data-track-action="click recommendations inline - 1" data-track-label="10.1038/s41598-022-20952-8">Evaluation of the relative potential for contact and doffing transmission of SARS-CoV-2 by a range of personal protective equipment materials </a> </h3> <div class="c-article-meta-recommendations" data-test="recommendation-info"> <span class="c-article-meta-recommendations__item-type">Article</span> <span class="c-article-meta-recommendations__access-type">Open access</span> <span class="c-article-meta-recommendations__date">05 October 2022</span> </div> </div> </article> </div> <div class="c-article-recommendations-list__item"> <article class="c-article-recommendations-card" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-article-recommendations-card__img"><img src="https://media.springernature.com/w215h120/springer-static/image/art%3Aplaceholder%2Fimages/placeholder-figure-springernature.png" loading="lazy" alt=""></div> <div class="c-article-recommendations-card__main"> <h3 class="c-article-recommendations-card__heading" itemprop="name headline"> <a class="c-article-recommendations-card__link" itemprop="url" href="https://link.springer.com/10.1007/s13337-020-00603-0?fromPaywallRec=false" data-track="select_recommendations_2" data-track-context="inline recommendations" data-track-action="click recommendations inline - 2" data-track-label="10.1007/s13337-020-00603-0">Inanimate surfaces as potential source of 2019-nCoV spread and their disinfection with biocidal agents </a> </h3> <div class="c-article-meta-recommendations" data-test="recommendation-info"> <span class="c-article-meta-recommendations__item-type">Article</span> <span class="c-article-meta-recommendations__date">05 June 2020</span> </div> </div> </article> </div> <div class="c-article-recommendations-list__item"> <article class="c-article-recommendations-card" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-article-recommendations-card__img"><img src="https://media.springernature.com/w215h120/springer-static/image/art%3A10.1007%2Fs10311-022-01462-5/MediaObjects/10311_2022_1462_Fig1_HTML.png" loading="lazy" alt=""></div> <div class="c-article-recommendations-card__main"> <h3 class="c-article-recommendations-card__heading" itemprop="name headline"> <a class="c-article-recommendations-card__link" itemprop="url" href="https://link.springer.com/10.1007/s10311-022-01462-5?fromPaywallRec=false" data-track="select_recommendations_3" data-track-context="inline recommendations" data-track-action="click recommendations inline - 3" data-track-label="10.1007/s10311-022-01462-5">Impact of waste of COVID-19 protective equipment on the environment, animals and human health: a review </a> </h3> <div class="c-article-meta-recommendations" data-test="recommendation-info"> <span class="c-article-meta-recommendations__item-type">Article</span> <span class="c-article-meta-recommendations__date">01 July 2022</span> </div> </div> </article> </div> </div> </section> <script> window.dataLayer = window.dataLayer || []; window.dataLayer.push({ recommendations: { recommender: 'semantic', model: 'specter', policy_id: 'NA', timestamp: 1732664922, embedded_user: 'null' } }); </script> <div class="app-card-service" data-test="article-checklist-banner"> <div> <a class="app-card-service__link" data-track="click_presubmission_checklist" data-track-context="article page top of reading companion" data-track-category="pre-submission-checklist" data-track-action="clicked article page checklist banner test 2 old version" data-track-label="link" href="https://beta.springernature.com/pre-submission?journalId=41207" data-test="article-checklist-banner-link"> <span class="app-card-service__link-text">Use our pre-submission checklist</span> <svg class="app-card-service__link-icon" aria-hidden="true" focusable="false"><use xlink:href="#icon-eds-i-arrow-right-small"></use></svg> </a> <p class="app-card-service__description">Avoid common mistakes on your manuscript.</p> </div> <div class="app-card-service__icon-container"> <svg class="app-card-service__icon" aria-hidden="true" focusable="false"> <use xlink:href="#icon-eds-i-clipboard-check-medium"></use> </svg> </div> </div> <div class="main-content"> <section data-title="Introduction"><div class="c-article-section" id="Sec1-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Sec1">Introduction</h2><div class="c-article-section__content" id="Sec1-content"><p>During a viral epidemic, personal protective equipment (PPE) plays a major role in protecting doctors, nurses, and other healthcare or emergency medical personnel from viral infections (Islam <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Islam A (2020) Use of PPE in response of coronavirus (COVID-19): a smart solution to global economic challenges? 
 https://doi.org/10.13140/RG.2.2.30872.34568
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR17" id="ref-link-section-d38942026e596">2020</a>). PPE is protective gear that has been fabricated from nonporous impermeable materials such as plastics to maintain a strategic distance between the PPE wearer and substances potentially contaminated with infectious viruses. This is the lowest level of equipment for preventing infections that can be used by any healthcare worker. However, the efficiency of a PPE kit depends on how carefully it is used (Phan et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2018" title="Phan LT, Maita D, Mortiz DC, Weber R, Fritzen-Pedicini C, Bleasdale SC, Jones RM (2018) Personal protective equipment doffing practices of healthcare workers. Am J Infect Control 46(6):S74" href="/article/10.1007/s41207-021-00251-w#ref-CR28" id="ref-link-section-d38942026e599">2018</a>). It is especially important to utilize PPE when a viable immunization or antiviral/antimicrobial vaccine is not yet available. Wearing PPE helps healthcare professionals and members of other specialist organizations to feel safe and to work successfully during pandemics (Andersen <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2019" title="Andersen BM (2019) Chap. 84: Personal protective equipment (PPE). In: Prevention and control of infections in hospitals. Springer International, Cham, pp 1061–1064. 
 https://doi.org/10.1007/978-3-319-99921-0
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR2" id="ref-link-section-d38942026e602">2019</a>).</p><p>To be transported into the environment, pathogens must be able to stay viable outside the host. How long a pathogen remains viable in the environment depends on the effects of numerous biotic and abiotic stresses on the pathogen (Wolff et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2005" title="Wolff MH, Sattar SA, Adegbunrin O, Tetro J (2005) Environmental survival and microbicide inactivation of coronaviruses. In: Schmidt A, Wolff MH, Weber O (eds) Coronaviruses with special emphasis on first insights concerning SARS. Birkhäuser, Basel, pp 201–212. 
 https://doi.org/10.1007/3-7643-7339-3_10
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR45" id="ref-link-section-d38942026e608">2005</a>). Viral infections such as COVID-19 spread from an infected person to a healthy person mainly through direct contact or aerosol generation, which indicates that environmental factors play a significant role in the spread of viral diseases. Environmental factors such as air humidity, ambient temperature, and polluted surfaces are critical influences on virus survival and subsequent transmission (Prussin et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2018" title="Prussin AJ 2nd, Schwake DO, Lin K, Gallagher DL, Buttling L, Marr LC (2018) Survival of the enveloped virus Phi6 in droplets as a function of relative humidity, absolute humidity, and temperature. Appl Environ Microbiol 84:e00551-e618" href="/article/10.1007/s41207-021-00251-w#ref-CR31" id="ref-link-section-d38942026e611">2018</a>). Healthcare workers must change their protective equipment after a certain period of time, and such equipment must be decontaminated using recommended standard procedures before being reused (Islam <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Islam A (2020) Use of PPE in response of coronavirus (COVID-19): a smart solution to global economic challenges? 
 https://doi.org/10.13140/RG.2.2.30872.34568
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR17" id="ref-link-section-d38942026e614">2020</a>; Phan et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2018" title="Phan LT, Maita D, Mortiz DC, Weber R, Fritzen-Pedicini C, Bleasdale SC, Jones RM (2018) Personal protective equipment doffing practices of healthcare workers. Am J Infect Control 46(6):S74" href="/article/10.1007/s41207-021-00251-w#ref-CR28" id="ref-link-section-d38942026e617">2018</a>; CDC <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020a" title="CDC (2020a) Operational considerations for personal protective equipment in the context of global supply shortages for coronavirus disease 2019 (COVID-19) pandemic: non-US healthcare settings. 
 https://www.cdc.gov/coronavirus/2019-ncov/hcp/non-us-settings/emergency-considerations-ppe.html
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR15" id="ref-link-section-d38942026e620">2020a</a>). Personal protective equipment should be worn in the manner specified in the guidelines of the World Health Organization (WHO) and decontaminated after use so that enveloped virus (SARS-CoV-2) on the outer surface is not transmitted to healthy individuals (Islam <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Islam A (2020) Use of PPE in response of coronavirus (COVID-19): a smart solution to global economic challenges? 
 https://doi.org/10.13140/RG.2.2.30872.34568
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR17" id="ref-link-section-d38942026e624">2020</a>). Hand sanitization is essential before and after using PPE, and a suitable protocol for wearing and removing it should be followed; not following such a protocol could lead to a high probability of virus transmission via PPE (Feng et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Feng S, Shen C, Xia N, Song W, Fan M, Cowling BJ (2020) Rational use of face masks in the COVID-19 pandemic. Lancet Respir Med 8:434–436. 
 https://doi.org/10.1016/S2213-2600(20)30134-X9
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR14" id="ref-link-section-d38942026e627">2020</a>; CDC <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020b" title="CDC (2020b) Social distancing. Keep your distance to slow the spread. Centers for Disease Control and Prevention, Atlanta. 
 http://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/social-distancing.html
 
 . Accessed 3 May 2020" href="/article/10.1007/s41207-021-00251-w#ref-CR8" id="ref-link-section-d38942026e630">2020b</a>). Due to the threat posed by infectious waste in hospitals and other emergency healthcare clinics, access to medical waste should not be granted without the permission of medical professionals. According to the WHO protocol, all PPE must be transferred safely to a sterilization facility for decontamination.</p><p>Hazardous healthcare waste normally comprises about 10% of the waste from healthcare facilities worldwide (World Health Organization <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2014" title="World Health Organization (2014) Safe management of wastes from health-care activities, 2nd edn. World Health Organization, Geneva, ISBN: 978-92-4-154856-4" href="/article/10.1007/s41207-021-00251-w#ref-CR46" id="ref-link-section-d38942026e636">2014</a>); however, during a pandemic, this proportion increases drastically. Also, while used PPE kits are not normally considered highly infectious waste (in contrast to waste contaminated with blood or other body fluids and laboratory cultures and stocks), they are considered highly infectious during pandemics. Therefore the collection, handling, transport, treatment, and disposal of PPE kits during a pandemic need special attention.</p><p>A national policy on healthcare waste disposal should allow for regional differences and variations in local capacity and socioeconomic conditions. International guidelines in this regard are available in the documents produced by the WHO, the United Nations Environment Programme—Secretariat of the Basel Convention, and several nongovernmental organizations (NGOs) (e.g., WHO <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2005" title="World Health Organization (WHO) (2005) Preparation of national medical waste management plans in Sub-Saharan countries, guidance manual. World Health Organization (WHO), Geneva" href="/article/10.1007/s41207-021-00251-w#ref-CR01" id="ref-link-section-d38942026e642">2005</a>). Among the international treaties, the Stockholm Convention is a notable global treaty to protect human health and the environment from persistent organic pollutants (POPs). The Stockholm Convention states that “priority consideration” should be given to alternative processes with a similar usefulness but that avoid the formation and release of organic pollutants. The best available technique (BAT) or best environmental practice (BEP) guidelines describe alternative technologies such as steam sterilization, advanced steam sterilization, microwave treatment, dry-heat sterilization, alkaline hydrolysis, and biological treatment (UNEP <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2006" title="UNEP (2006) Water and wastewater reuse: an environmentally sound approach for sustainable urban water management" href="/article/10.1007/s41207-021-00251-w#ref-CR03" id="ref-link-section-d38942026e645">2006</a>) for the disinfection of healthcare wastes in general (World Health Organization <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2014" title="World Health Organization (2014) Safe management of wastes from health-care activities, 2nd edn. World Health Organization, Geneva, ISBN: 978-92-4-154856-4" href="/article/10.1007/s41207-021-00251-w#ref-CR46" id="ref-link-section-d38942026e648">2014</a>). It should be noted that the treaties, policies, and guidelines (national and international) framed by different countries and international bodies are general protocols for the management of healthcare wastes; they are not specific to PPE. Until now, only 24% of the countries around the world have adopted dedicated healthcare legislation on waste management. However, very recently (after the COVID-19 pandemic started in 2019), the Institute of Global Environmental Strategies (IGES) and the WHO jointly published a fine report entitled<i> Waste Management During the COVID-19 Pandemic: From Response to Recovery</i> under the United Nations Environment Programme (<a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="United Nations Environment Programme (2020) Waste management during the COVID-19 pandemic, from response to recovery. United Nations Environment Programme, Nairobi, ISBN: 978-92-807-3794-3" href="/article/10.1007/s41207-021-00251-w#ref-CR41" id="ref-link-section-d38942026e654">2020</a>), in which they provide clear instructions for health workers on the proper use of PPE (collection, transfer station, informal sector, etc.). The report also focuses on the management of healthcare waste during the COVID-19 pandemic, covering healthcare waste generated by hospitals, medical centers, and emergency medical facilities as well as municipal solid waste (MSW).</p><p>Although there are no specific and well-planned strategies for PPE disposal and reutilization at the national or international level, the severity and devastating nature of COVID-19 have prompted governments and governmental statutory bodies in several countries to formulate contingency plans. For example, the CPCB (Central Pollution Control Board) of India states that used PPE (such as face shields, goggles, hazmat suits, plastic coveralls, masks, head covers, and shoe covers) from COVID-19 isolation wards at healthcare facilities should be segregated and sent to common facilities for disposal as per biomedical waste management rules (BMWM rules). However, used PPE (such as masks and gloves) from households, commercial establishments, and institutions must be stored separately for a minimum of 72 h, cut and shredded, and then disposed along with solid waste (Times of India <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Times of India (2020) Disposal of PPE kits, other biomedical waste challenge durin Covid-19 pandemic: Government. 
 https://timesofindia.indiatimes.com/india/disposal-of-ppe-kits-other-biomedical-waste-challenge-during-covid-19-pandemic-government/articleshow/78216731.cms
 
 . Accessed 15 Dec 2020" href="/article/10.1007/s41207-021-00251-w#ref-CR40" id="ref-link-section-d38942026e661">2020</a>). Similarly, the European Centre for Disease Prevention and Control (ECDC) has provided guidelines for the selection, handling, and disposal of PPE kits (ECDC <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="ECDC (2020) Guidance for wearing and removing personal protective
equipment in healthcare settings for the care of patients
with suspected or confirmed COVID-19. Technical report. 
 https://www.ecdc.europa.eu/sites/default/files/documents/COVID-19-guidance-wearing-and-removing-personal-protective-equipment-healthcare-settings-updated.pdf
 
 . Accessed 15 Dec 2020" href="/article/10.1007/s41207-021-00251-w#ref-CR12" id="ref-link-section-d38942026e664">2020</a>). The US Food and Drug Administration (FDA) provides clear guidelines on the selection, utilization, and reutilization of PPE (FDA <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="FDA (2020) Questions about personal protective equipment (PPE). 
 https://www.fda.gov/medical-devices/personal-protective-equipment-infection-control/questions-about-personal-protective-equipment-ppe
 
 . Accessed 15 Dec 2020" href="/article/10.1007/s41207-021-00251-w#ref-CR13" id="ref-link-section-d38942026e667">2020</a>), and the Army Public Health Center (APHC) has published lucid guidelines on the disposal of PPE kits for workers caring for COVID-19 and non-COVID-19 patients that follow the FDA guidelines (APHC <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="APHC (2020) Personal protective equipment disposal. 
 https://phc.amedd.army.mil/topics/campaigns/covid19/Pages/ppe-disposal-aspx.aspx
 
 . Accessed 15 Dec 2020" href="/article/10.1007/s41207-021-00251-w#ref-CR30" id="ref-link-section-d38942026e670">2020</a>).</p><p>Many countries do not have the proper facilities to treat contaminated PPE kits, so they are dumped on landfills. This was one of the motivations for the present paper, which reviews various aspects of PPE usage and enveloped virus transmission and reports a modeling study of the diffusion of the coronavirus through a porous medium (soil here) via the leaching of contaminated water.</p></div></div></section><section data-title="PPE and enveloped virus transmission"><div class="c-article-section" id="Sec2-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Sec2">PPE and enveloped virus transmission</h2><div class="c-article-section__content" id="Sec2-content"><p>Personal protective equipment should include eye and face protection, hand protection (disposable gloves), respiratory protection (an N95 mask or equivalent), skin and body protection, head protection, and reusable leather boots (Mahmood et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Mahmood S, Crimbly F, Khan S et al (2020) Strategies for rational use of personal protective equipment (PPE) among healthcare providers during the COVID-19 crisis. Cureus 12(5):e8248. 
 https://doi.org/10.7759/cureus.8248
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR25" id="ref-link-section-d38942026e684">2020</a>). In Table <a data-track="click" data-track-label="link" data-track-action="table anchor" href="/article/10.1007/s41207-021-00251-w#Tab1">1</a>, we list materials that are commonly utilized to manufacture PPE components. If any of these PPE components comes into contact with an infected patient, the entire PPE kit should be discarded in a scientific way, as instructed by the local regulatory authority. Therefore, every component of a single-use PPE kit is selected with contamination and safety control in mind. Gloves are the most commonly discarded PPE component utilized by healthcare professionals around the world, as they are strictly for single use. They should be changed after direct contact with an infected patient, otherwise the gloves could help the disease to spread (Loveday et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2014" title="Loveday HP, Wilson JA, Pratt RJ, Golsorkhi M, Tingle A, Bak A, Browne J, Prieto J, Wilcox M (2014) Epic3: national evidence-based guidelines for preventing healthcare associated infections in NHS hospitals in England. J Hosp Infect 86(Suppl. 1):1–70. 
 https://doi.org/10.1016/S0195-6701(13)60012-2
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR24" id="ref-link-section-d38942026e690">2014</a>). Other components of a PPE kit can be reused after appropriate decontamination. PPE sterilization has become an economic and useful step due to the increased demand for such components during the COVID-19 epidemic. The general sterilization procedure involves autoclaving the components at 121 °C for 15 min (Wilson and Nayak <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2013" title="Wilson AJ, Nayak S (2013) Disinfection, sterilization and disposables. Anaesth Intensive Care Med 14:423–427" href="/article/10.1007/s41207-021-00251-w#ref-CR43" id="ref-link-section-d38942026e693">2013</a>). PPE components such as skin protectors (gowns), shoes, and face protectors (masks) can easily be decontaminated using a neutral detergent or disinfectant such as 0.5% chlorine solution (Rutala and Weber <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2016" title="Rutala WA, Weber DJ (2016) Disinfection, sterilization and antisepsis: an overview. Am J Infect Control 44:e1–6. 
 https://doi.org/10.1016/j.ajic.2015.10.038
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR35" id="ref-link-section-d38942026e696">2016</a>). However, there are some disadvantages of reusing PPE; for instance, heat-resistant viruses may remain active after thermal sterilization (Riley et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2017" title="Riley K, Fergusson M, Shen J (2017) Sustainable fabric choice for regularly laundered healthcare uniforms. J Text Inst 108:440–444. 
 https://doi.org/10.1080/00405000.2016.1171025
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR32" id="ref-link-section-d38942026e700">2017</a>).</p><div class="c-article-table" data-test="inline-table" data-container-section="table" id="table-1"><figure><figcaption class="c-article-table__figcaption"><b id="Tab1" data-test="table-caption">Table 1 Materials used in different PPE components</b></figcaption><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="table-link" data-track="click" data-track-action="view table" data-track-label="button" rel="nofollow" href="/article/10.1007/s41207-021-00251-w/tables/1" aria-label="Full size table 1"><span>Full size table</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div></div></div></section><section data-title="Disposal of PPE kits"><div class="c-article-section" id="Sec3-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Sec3">Disposal of PPE kits</h2><div class="c-article-section__content" id="Sec3-content"><p>Personal protective equipment must be free from any kind of contaminant, as any kind of infectious substance on the PPE could be transmitted to and harm a healthy individual (Mahmood et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Mahmood S, Crimbly F, Khan S et al (2020) Strategies for rational use of personal protective equipment (PPE) among healthcare providers during the COVID-19 crisis. Cureus 12(5):e8248. 
 https://doi.org/10.7759/cureus.8248
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR25" id="ref-link-section-d38942026e841">2020</a>; IRIS <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="IRIS (2020) Rational use of personal protective equipment (PPE) for coronavirus disease (COVID-19): interim guidance, 19 March 2020. 
 http://apps.who.int/iris/handle/10665/331498
 
 . Accessed 3 May 2020" href="/article/10.1007/s41207-021-00251-w#ref-CR16" id="ref-link-section-d38942026e844">2020</a>). All the components of single-use PPE should be treated appropriately, whereas reusable PPE should be sterilized before reutilization according to an appropriate decontamination procedure (Islam <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Islam A (2020) Use of PPE in response of coronavirus (COVID-19): a smart solution to global economic challenges? 
 https://doi.org/10.13140/RG.2.2.30872.34568
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR17" id="ref-link-section-d38942026e847">2020</a>; Phan et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2018" title="Phan LT, Maita D, Mortiz DC, Weber R, Fritzen-Pedicini C, Bleasdale SC, Jones RM (2018) Personal protective equipment doffing practices of healthcare workers. Am J Infect Control 46(6):S74" href="/article/10.1007/s41207-021-00251-w#ref-CR28" id="ref-link-section-d38942026e850">2018</a>; CDC <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020a" title="CDC (2020a) Operational considerations for personal protective equipment in the context of global supply shortages for coronavirus disease 2019 (COVID-19) pandemic: non-US healthcare settings. 
 https://www.cdc.gov/coronavirus/2019-ncov/hcp/non-us-settings/emergency-considerations-ppe.html
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR15" id="ref-link-section-d38942026e853">2020a</a>). However, it is important to consider whether the decontamination process will cause the PPE to lose its protective ability. When properly disposing of single-use PPE, it should be safely stored by the hospital or laboratory in a separate supervised area. PPE components such as masks and eye and skin protectors can be reused after any of the following decontamination processes:</p><ul class="u-list-style-bullet"> <li> <p>Protective masks such as N95 can be sterilized by applying 7.5% hydrogen peroxide solution or 0.2% peracetic acid solution for 8–45 min at 20 °C. However, this disinfection process can reduce the efficacy of masks by blocking the pores in their internal layers. In such cases, the respirator must be replaced (Chakraborty et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Chakraborty S, Mondal R, Singh RK, Majumdar M, Kaba M (2020) COVID-19 pandemic: pharmacological uses of plants to boost immune system. Res J Med Health Sci 1(1). 
 https://royalliteglobal.com/health-sciences/article/view/386
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR9" id="ref-link-section-d38942026e863">2020</a>).</p> </li> <li> <p>The clothes can be dipped in 70% ethyl alcohol solution or 100 ppm chlorine solution for more than 1 min (Lamptey <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Lamptey E (2020) Psychological impacts of COVID-19 on health professionals: a cross-sectional survey of 1000 nurses across ECOWAS countries. Res J Med Health Sci 1(1). 
 https://royalliteglobal.com/health-sciences/article/view/290
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR21" id="ref-link-section-d38942026e872">2020</a>). Clothes should be checked for holes before sterilization; if any hole is found, the clothing must be discarded according to the hospital guidelines.</p> </li> <li> <p>Continuous washing using detergent is the method most commonly used to decontaminate leather boots. After detergent treatment, the boots should be dried quickly in sterilized warm air to reduce cross-contamination (Mahmood et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Mahmood S, Crimbly F, Khan S et al (2020) Strategies for rational use of personal protective equipment (PPE) among healthcare providers during the COVID-19 crisis. Cureus 12(5):e8248. 
 https://doi.org/10.7759/cureus.8248
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR25" id="ref-link-section-d38942026e881">2020</a>).</p> </li> <li> <p>Goggles can be reutilized after wiping them with a disinfectant such as 60–90% ethanol or 2–4% aqueous chlorhexidine. Alcohol-based rubbing is the most basic and effective sterilization process for eye protectors; it is even more effective than detergent solutions. However, as a precautionary measure, the healthcare worker should sanitize their hands before wiping the goggles (Boyce and Pittet <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2002" title="Boyce JM, Pittet D (2002) Guideline for hand hygiene in health-care settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Am J Infect Control 30(8):S1–S46" href="/article/10.1007/s41207-021-00251-w#ref-CR3" id="ref-link-section-d38942026e890">2002</a>).</p> </li> </ul><p>Vapor-phase hydrogen peroxide (VPHP) treatment, thermal disinfection (heat) treatment, ultraviolet germicidal irradiation (UVGI), ethylene oxide (EtO), and bleaching (sodium hypochlorite) treatment are generally used to systematically disinfect PPE. Among these, UVGI and EtO treatment effectively decontaminate PPE components without affecting their protective performance or physical appearance. On the other hand, a single cycle of VPHP treatment does not have a significant effect on respirator performance or appearance. While bleaching (0.1% sodium hypochlorite) treatment does not affect the appearance or performance of the treated respirator, the residual odor of bleach following the treatment is a potential health risk. In fact, even the presence of a low concentration of this chemical led researchers to discourage the use of bleach for decontamination. The effectiveness of common decontamination techniques has been nicely reviewed by Kharbat et al. (<a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Kharbat A, Mizer A, Zumwalt M (2020) Decontamination methods of personal protective equipment for repeated utilization in medical/surgical settings. Southwest Respir Crit Care Chron 8(34):27–39. 
 https://doi.org/10.12746/swrccc.v8i34.677
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR18" id="ref-link-section-d38942026e898">2020</a>).</p></div></div></section><section data-title="Factors affecting virus survival rates"><div class="c-article-section" id="Sec4-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Sec4">Factors affecting virus survival rates</h2><div class="c-article-section__content" id="Sec4-content"><p>There are several factors that affect the ability of enveloped virus (SARS-CoV-2) to retain its infectivity for a certain period of time on a surface. Environmental factors influence this ability in different ways, with each having some favorable and unfavorable effects. Physical factors include the ambient humidity, temperature, and sunlight (Kim et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2018" title="Kim Y, Krishna VD, Torremorell M, Goyal SM, Cheeran MC-J (2018) Stability of porcine epidemic diarrhea virus on fomite materials at different temperatures. Vet Sci 5:21" href="/article/10.1007/s41207-021-00251-w#ref-CR19" id="ref-link-section-d38942026e909">2018</a>; Casanova et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2010a" title="Casanova LM, Jeon S, Rutala WA, Weber DJ, Sobsey MD (2010a) Effects of air temperature and relative humidity on coronavirus survival on surfaces. Appl Environ Microbiol 76:2712–2717" href="/article/10.1007/s41207-021-00251-w#ref-CR5" id="ref-link-section-d38942026e912">2010a</a>, <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference b" title="Casanova L, Rutala WA, Weber DJ, Sobsey MD (2010b) Coronavirus survival on healthcare personal protective equipment. Infect Control Hosp Epidemiol 31:560–561" href="/article/10.1007/s41207-021-00251-w#ref-CR6" id="ref-link-section-d38942026e915">b</a>; Lin and Marr <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Lin K, Marr LC (2020) Humidity-dependent decay of viruses, but not bacteria, in aerosols and droplets follows disinfection kinetics. Environ Sci Technol 54:1024–1032" href="/article/10.1007/s41207-021-00251-w#ref-CR23" id="ref-link-section-d38942026e918">2020</a>). There are also some chemical and biological factors (Ye et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2018" title="Ye Y, Chang PH, Hartert J, Wigginton KR (2018) Reactivity of enveloped virus genome, proteins, and lipids with free chlorine and UV254. Environ Sci Technol 52:7698–7708" href="/article/10.1007/s41207-021-00251-w#ref-CR47" id="ref-link-section-d38942026e921">2018</a>) that affect the viability of a virus on a surface (Fig. <a data-track="click" data-track-label="link" data-track-action="figure anchor" href="/article/10.1007/s41207-021-00251-w#Fig1">1</a>). While some environmental factors aid virus transmission, a few suppress the spread of enveloped virus (SARS-CoV-2) to healthy individuals.</p><div class="c-article-section__figure js-c-reading-companion-figures-item" data-test="figure" data-container-section="figure" id="figure-1" data-title="Fig. 1"><figure><figcaption><b id="Fig1" class="c-article-section__figure-caption" data-test="figure-caption-text">Fig. 1</b></figcaption><div class="c-article-section__figure-content"><div class="c-article-section__figure-item"><a class="c-article-section__figure-link" data-test="img-link" data-track="click" data-track-label="image" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/1" rel="nofollow"><picture><img aria-describedby="Fig1" src="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig1_HTML.png" alt="figure 1" loading="lazy" width="685" height="396"></picture></a></div><div class="c-article-section__figure-description" data-test="bottom-caption" id="figure-1-desc"><p>Factors that affect virus survival in the environment</p></div></div><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="article-link" data-track="click" data-track-label="button" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/1" data-track-dest="link:Figure1 Full size image" aria-label="Full size image figure 1" rel="nofollow"><span>Full size image</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div></div></div></section><section data-title="Virus transmission modes"><div class="c-article-section" id="Sec5-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Sec5">Virus transmission modes</h2><div class="c-article-section__content" id="Sec5-content"><p>Infectious viruses can be spontaneously transmitted from one person to another in several ways. In the particular case of SARS-CoV-2, infected people who are asymptomatic are more likely to spread the infection (Robel et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Robel Y, Medhin S, Abigiya W, Sewit T, Hanna N, Bethelhem F, Mirgisa K, Abebaw F (2020) COVID-19: initial synthesis of the epidemiology, pathogenesis, diagnosis, treatment, and public health control approaches. Ethiop J Health Dev 34(2):129–140" href="/article/10.1007/s41207-021-00251-w#ref-CR33" id="ref-link-section-d38942026e953">2020</a>). Enveloped virus (SARS-CoV-2) can be transmitted between people in relatively close contact, but it can also remain viable on a surface after being discharged from the host organism. If a healthy individual stays in the same room as an infected person, it is possible that she/he can be infected through air movement. However, not all viruses present airborne transmission (e.g., HCV and HIV do not), and the potential for airborne contamination with SARS-CoV-2 and enveloped viruses is yet to be confirmed (Andersen <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2019" title="Andersen BM (2019) Chap. 84: Personal protective equipment (PPE). In: Prevention and control of infections in hospitals. Springer International, Cham, pp 1061–1064. 
 https://doi.org/10.1007/978-3-319-99921-0
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR2" id="ref-link-section-d38942026e956">2019</a>; Wolff et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2005" title="Wolff MH, Sattar SA, Adegbunrin O, Tetro J (2005) Environmental survival and microbicide inactivation of coronaviruses. In: Schmidt A, Wolff MH, Weber O (eds) Coronaviruses with special emphasis on first insights concerning SARS. Birkhäuser, Basel, pp 201–212. 
 https://doi.org/10.1007/3-7643-7339-3_10
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR45" id="ref-link-section-d38942026e959">2005</a>). Examples of enveloped viruses include ebola, avian flu virus, Zika, MERS, and the recently discovered SARS-CoV-2 coronavirus. Recent studies have revealed that enveloped viruses have a lipid bilayer on their cell walls and they can mutate over time. These structural properties help enveloped viruses to remain stable when they are under stress (Krista and Alexandria <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Krista RW, Alexandria BB (2020) Environmental engineers and scientists have important roles to play in stemming outbreaks and pandemics caused by enveloped viruses. Environ Sci Technol 54(7):3736–3739. 
 https://doi.org/10.1021/acs.est.0c01476
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR20" id="ref-link-section-d38942026e962">2020</a>). Coronaviruses can be transmitted through the air, via droplets, by direct contact with an infected person, and through fecal matter (Cai et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Cai J, Sun W, Huang J, Gamber M, Wu J, He G (2020) Indirect virus transmission in cluster of COVID-19 cases, Wenzhou, China. Emerging Infect Dis 26:1343–1345. 
 https://doi.org/10.3201/eid2606.200412
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR4" id="ref-link-section-d38942026e965">2020</a>; van Doremalen et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="van Doremalen N, Bushmaker T, Morris DH et al (2020) Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med 382(16):1564–1567. 
 https://doi.org/10.1056/NEJMc2004973
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR42" id="ref-link-section-d38942026e969">2020</a>).</p><p>Transmission through an aerosol is the most common way of spreading enveloped viruses. An aerosol is a suspension of small water droplets generated by sneezing and talking (Nicas et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2005" title="Nicas M, Nazaroff WW, Hubbard A (2005) Toward understanding the risk of secondary airborne infection: emission of respirable pathogens. J Occup Environ Hyg 2:143–154" href="/article/10.1007/s41207-021-00251-w#ref-CR26" id="ref-link-section-d38942026e975">2005</a>; Cook <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Cook TM (2020) Personal protective equipment during the coronavirus disease (COVID) 2019 pandemic—a narrative review. Anaesthesia 75:920–927. 
 https://doi.org/10.1111/anae.15071
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR11" id="ref-link-section-d38942026e978">2020</a>; Chan et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2004" title="Chan KH, Poon LLLM, Cheng VCC, Guan Y, Hung IFN, Kong J, Yam LYC, Seto WH, Yuen KY, Peiris JSM (2004) Detection of SARS coronavirus in patients with suspected SARS. Emerging Infect Dis 10(2):294–299" href="/article/10.1007/s41207-021-00251-w#ref-CR10" id="ref-link-section-d38942026e981">2004</a>; Yu et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2004" title="Yu ITS, Li Y, Wong TW, Tam W, Chan AT, Lee JHW, Leung DYC, Ho T (2004) Evidence of airborne transmission of the severe acute respiratory syndrome virus. N Engl J Med 350:1731–1739" href="/article/10.1007/s41207-021-00251-w#ref-CR48" id="ref-link-section-d38942026e984">2004</a>). Such water droplets have an average diameter of less than 5 µm. Infected droplets can travel a small distance (less than 2 m) through the air. After entering the air, gravity causes enveloped virus (SARS-CoV-2) to settle and land on a surface (van Doremalen et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="van Doremalen N, Bushmaker T, Morris DH et al (2020) Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med 382(16):1564–1567. 
 https://doi.org/10.1056/NEJMc2004973
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR42" id="ref-link-section-d38942026e987">2020</a>). However, smaller droplets can travel further than bigger ones. Whereas bigger droplets take less time to settle under the influence of gravity, smaller droplets tend to remain in the air for a longer period of time. Air movement greatly affects the settling time of enveloped virus (SARS-CoV-2). Air turbulence is directly proportional to the time taken for enveloped virus (SARS-CoV-2) to settle down (Nicas et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2005" title="Nicas M, Nazaroff WW, Hubbard A (2005) Toward understanding the risk of secondary airborne infection: emission of respirable pathogens. J Occup Environ Hyg 2:143–154" href="/article/10.1007/s41207-021-00251-w#ref-CR26" id="ref-link-section-d38942026e991">2005</a>). If the droplet diameter is less than 10 µm, enveloped virus (SARS-CoV-2) reaches the lungs directly through the respiratory tract. To prevent disease transmission through aerosols, social distancing should be maintained, and gloves, an N95 face mask, eye protection, and a flower-sleeve gown should be worn by healthcare workers (Cook <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Cook TM (2020) Personal protective equipment during the coronavirus disease (COVID) 2019 pandemic—a narrative review. Anaesthesia 75:920–927. 
 https://doi.org/10.1111/anae.15071
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR11" id="ref-link-section-d38942026e994">2020</a>). Viral transmission can happen through direct contact with an infected patient’s body liquids or through contact with fomites (tainted inanimate items and surfaces, e.g., the floor, utensils, and bedclothes that have recently been contaminated with body liquids) (Stowell et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2012" title="Stowell JD, Forlin-Passoni D, Din E et al (2012) Cytomegalovirus survival on common environmental surfaces: opportunities for viral transmission. J Infect Dis 205(2):211–214. 
 https://doi.org/10.1093/infdis/jir722
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR38" id="ref-link-section-d38942026e997">2012</a>). Disease can be transmitted through broken skin and wounds (e.g., needlestick injuries). Previous studies have demonstrated that most of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) viruses remain viable in adults after 60 min of aerosolization (Islam <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Islam A (2020) Use of PPE in response of coronavirus (COVID-19): a smart solution to global economic challenges? 
 https://doi.org/10.13140/RG.2.2.30872.34568
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR17" id="ref-link-section-d38942026e1000">2020</a>; Oran and Topol <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Oran DP, Topol EJ (2020) Prevalence of asymptomatic SARS-CoV-2 infection. Ann Int Med 173:362–367. 
 https://doi.org/10.7326/M20-3012
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR27" id="ref-link-section-d38942026e1003">2020</a>). Enveloped virus (SARS-CoV-2) can be transmitted through stool, mucus, and serum but is usually less stable in the urine. Contaminated stools represent a danger to human health, but they can be washed away with water. Fecal transmission of enveloped virus (SARS-CoV-2) is possible because enveloped virus (SARS-CoV-2) can survive in the human gastrointestinal (GI) tract before entering the environment in human stools (Oran and Topol <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Oran DP, Topol EJ (2020) Prevalence of asymptomatic SARS-CoV-2 infection. Ann Int Med 173:362–367. 
 https://doi.org/10.7326/M20-3012
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR27" id="ref-link-section-d38942026e1006">2020</a>). Virus transmission can also occur indirectly via inanimate substances such as polluted surfaces, clothes, and materials. Enveloped viruses have the ability to resist abiotic and biotic environmental stress and survive on open surfaces, infecting healthy individuals through the nose, mouth, and eyes. The survival time of viruses on porous surfaces is shorter than that on nonporous surfaces (more than 72 h) (Phan et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2019" title="Phan LT, Maita D, Mortiz DC, Weber R, Fritzen-Pedicini C, Bleasdale SC, Jones RM, CDC Prevention Epicenter Program (2019) Personal protective equipment doffing practices of healthcare workers. J Occup Environ Hyg 16(8):575–581. 
 https://doi.org/10.1080/15459624.2019.1628350
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR29" id="ref-link-section-d38942026e1010">2019</a>).</p></div></div></section><section data-title="Preventive measures and PPE disposal"><div class="c-article-section" id="Sec6-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Sec6">Preventive measures and PPE disposal</h2><div class="c-article-section__content" id="Sec6-content"><p>The PPE sterilization procedures discussed above should be followed to maintain a hygienic environment and prevent virus transmission. Hydrogen peroxide has been used in conjunction with steam to disinfect porous materials such as masks. It is a reliable disinfectant that is widely used worldwide because it does not block the pores of masks and does not damage their inner layers. Ethyl alcohol is another effective sanitizing agent and virucide. 70% ethyl alcohol is used to disinfect PPE clothing and eye protectors, as it kills or destroys more than 90% of microorganisms, including viruses and bacteria. So, after washing them with ethyl alcohol, PPE components are completely free of contamination. Disinfection methods are currently particularly important due to shortages of PPE (Mahmood et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Mahmood S, Crimbly F, Khan S et al (2020) Strategies for rational use of personal protective equipment (PPE) among healthcare providers during the COVID-19 crisis. Cureus 12(5):e8248. 
 https://doi.org/10.7759/cureus.8248
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR25" id="ref-link-section-d38942026e1022">2020</a>). The best way to overcome this shortage is to regularly decontaminate the PPE that is available so that it can be reused. Disinfecting PPE kits instead of discarding them after a single use is also financially prudent, as these kits are expensive to produce and therefore purchase. As per hospital guidelines, other infectious clinical waste should be discarded in a separate place.</p><p>PPE kits that are in very poor condition should be disposed of in a separate container. Kit components such as damaged gowns, defective masks, and blood-stained materials are considered to be in poor condition and should not be reused. Some of the basic precautionary steps that should be implemented to deal with defective PPE (Krista and Alexandria <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Krista RW, Alexandria BB (2020) Environmental engineers and scientists have important roles to play in stemming outbreaks and pandemics caused by enveloped viruses. Environ Sci Technol 54(7):3736–3739. 
 https://doi.org/10.1021/acs.est.0c01476
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR20" id="ref-link-section-d38942026e1028">2020</a>) are summarized in Table <a data-track="click" data-track-label="link" data-track-action="table anchor" href="/article/10.1007/s41207-021-00251-w#Tab2">2</a>.</p><div class="c-article-table" data-test="inline-table" data-container-section="table" id="table-2"><figure><figcaption class="c-article-table__figcaption"><b id="Tab2" data-test="table-caption">Table 2 Some precautionary steps that should be followed during the disposal of PPE kits (Robel et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Robel Y, Medhin S, Abigiya W, Sewit T, Hanna N, Bethelhem F, Mirgisa K, Abebaw F (2020) COVID-19: initial synthesis of the epidemiology, pathogenesis, diagnosis, treatment, and public health control approaches. Ethiop J Health Dev 34(2):129–140" href="/article/10.1007/s41207-021-00251-w#ref-CR33" id="ref-link-section-d38942026e1044">2020</a>)</b></figcaption><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="table-link" data-track="click" data-track-action="view table" data-track-label="button" rel="nofollow" href="/article/10.1007/s41207-021-00251-w/tables/2" aria-label="Full size table 2"><span>Full size table</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div><p>People involved in the disposal process should also wear PPE kit correctly. All the appropriate precautionary steps must be taken by healthcare organizations and their workers to avoid the dangerous consequences of exposure to viral diseases. Only medical professionals should be allowed to have direct contact with patients. According to medical experts, while these practices do not guarantee complete prevention of viral infections, they can prevent early transmission of enveloped virus (SARS-CoV-2). Regardless of the current situation, the emergency procedures recommended by the Centers for Disease Control and Prevention (CDC) should be followed (Phan et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2019" title="Phan LT, Maita D, Mortiz DC, Weber R, Fritzen-Pedicini C, Bleasdale SC, Jones RM, CDC Prevention Epicenter Program (2019) Personal protective equipment doffing practices of healthcare workers. J Occup Environ Hyg 16(8):575–581. 
 https://doi.org/10.1080/15459624.2019.1628350
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR29" id="ref-link-section-d38942026e1110">2019</a>; Rohrer et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Rohrer M, Flahault A, Stoffel M (2020) Peaks of fine particulate matter may modulate the spreading and virulence of COVID-19. Earth Syst Environ 4:789–796. 
 https://doi.org/10.1007/s41748-020-00184-4
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR34" id="ref-link-section-d38942026e1113">2020</a>; Lessler et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2009" title="Lessler J, Reich NG, Brookmeyer R, Perl TM, Nelson KE, Cummings DA (2009) Incubation periods of acute respiratory viral infections: a systematic review. Lancet Infect Dis 9(5):291–300. 
 https://doi.org/10.1016/S1473-3099(09)70069-6
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR22" id="ref-link-section-d38942026e1116">2009</a>). The current epidemic (COVID-19) is thought to be transmitted through direct contact and airborne routes, and has been spreading from individual to individual for the last 12 months. The SARS-CoV-2 virus is considered to be more dangerous than other SARS viruses because it can remain at an asymptomatic stage in a healthy person. At this stage, the person does not show any symptoms of the disease but they can still transmit enveloped virus (SARS-CoV-2). Therefore, all the precautionary measures discussed earlier should be followed during this viral epidemic.</p><p>If disinfection is not performed properly, viruses attached to the PPE surface can become contagious and infect healthy people. On the PPE surface, enveloped virus (SARS-CoV-2) is subject to many environmental stresses but retains its infectivity (Chan et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2004" title="Chan KH, Poon LLLM, Cheng VCC, Guan Y, Hung IFN, Kong J, Yam LYC, Seto WH, Yuen KY, Peiris JSM (2004) Detection of SARS coronavirus in patients with suspected SARS. Emerging Infect Dis 10(2):294–299" href="/article/10.1007/s41207-021-00251-w#ref-CR10" id="ref-link-section-d38942026e1122">2004</a>). The humidity of the air is a major influence on virus survival. If the relative humidity is 50%, enveloped virus (SARS-CoV-2) can survive well and replicate freely. As the relative humidity increases, the enveloped virus survival rate decreases. Enveloped viruses have lipid bilayers in their cell walls, and this unique property helps them to survive at low humidity levels. The environmental temperature also affects virus survival on the PPE surface. High temperatures are harmful to enveloped virus (SARS-CoV-2), while low temperatures can help enveloped virus (SARS-CoV-2) to remain viable for longer (1–2 days). Sunlight is the main source of heat (elevated temperature) in the environment. The UV radiation in sunlight kills some viruses, but enveloped viruses can survive exposure to UV radiation and daylight due to their lipid bilayers. However, enveloped virus (SARS-CoV-2) survives best in darkness rather than daylight (Sagripanti and Lytle <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Sagripanti J-L, Lytle CD (2020) Estimated inactivation of coronaviruses by solar radiation with special reference to COVID-19. Photochem Photobiol 96:731–737. 
 https://doi.org/10.1111/php.13293
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR36" id="ref-link-section-d38942026e1125">2020</a>; Casanova et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2010c" title="Casanova LM, Jeon S, Rutala WA, Weber DJ, Sobsey MD (2010c) Effects of air temperature and relative humidity on coronavirus survival on surfaces. Appl Environ Microbiol 76(9):2712–2717. 
 https://doi.org/10.1128/AEM.02291-09
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR7" id="ref-link-section-d38942026e1128">2010c</a>).</p></div></div></section><section data-title="Factors affecting virus transmission"><div class="c-article-section" id="Sec7-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Sec7">Factors affecting virus transmission</h2><div class="c-article-section__content" id="Sec7-content"><p>Several factors are responsible for not only the transmission of viruses but also their deactivation. Figure <a data-track="click" data-track-label="link" data-track-action="figure anchor" href="/article/10.1007/s41207-021-00251-w#Fig2">2</a> shows the relationship between virus inactivation and humidity (%). At constant temperature, enveloped virus (SARS-CoV-2) survival rate increases when the relative humidity is less than 50% or more than 90%. Increasing the relative humidity from 60% to 80% causes enveloped virus (SARS-CoV-2) survival rate to gradually decrease (Prussin et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2018" title="Prussin AJ 2nd, Schwake DO, Lin K, Gallagher DL, Buttling L, Marr LC (2018) Survival of the enveloped virus Phi6 in droplets as a function of relative humidity, absolute humidity, and temperature. Appl Environ Microbiol 84:e00551-e618" href="/article/10.1007/s41207-021-00251-w#ref-CR31" id="ref-link-section-d38942026e1142">2018</a>). As the humidity increases, enveloped virus (SARS-CoV-2) remains stable in respiratory droplets for longer, so the rate of infection does not decrease considerably. As the relative humidity increases from 60% to 70%, the rate of viral infection via aerosols and droplets gradually increases (Stowell et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2012" title="Stowell JD, Forlin-Passoni D, Din E et al (2012) Cytomegalovirus survival on common environmental surfaces: opportunities for viral transmission. J Infect Dis 205(2):211–214. 
 https://doi.org/10.1093/infdis/jir722
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR38" id="ref-link-section-d38942026e1145">2012</a>). As can be seen in Fig. <a data-track="click" data-track-label="link" data-track-action="figure anchor" href="/article/10.1007/s41207-021-00251-w#Fig2">2</a>b, for a specific relative humidity, the rate of virus inactivation gradually decreases with increasing temperature. The viral load and the infectivity of enveloped virus (SARS-CoV-2) are higher at low temperatures, such as between 15 and 20 °C, than at higher temperatures. Virus infectivity decreases with temperature, as increasing the temperature has a negative effect on virus survivability (Wolde <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Wolde M (2020) Hematology, immunology and clinical chemistry profiles of COVID-19 patients: systematic review. Ethiop J Health Dev 34(3):226–231" href="/article/10.1007/s41207-021-00251-w#ref-CR44" id="ref-link-section-d38942026e1151">2020</a>).</p><div class="c-article-section__figure js-c-reading-companion-figures-item" data-test="figure" data-container-section="figure" id="figure-2" data-title="Fig. 2"><figure><figcaption><b id="Fig2" class="c-article-section__figure-caption" data-test="figure-caption-text">Fig. 2</b></figcaption><div class="c-article-section__figure-content"><div class="c-article-section__figure-item"><a class="c-article-section__figure-link" data-test="img-link" data-track="click" data-track-label="image" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/2" rel="nofollow"><picture><source type="image/webp" srcset="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig2_HTML.png?as=webp"><img aria-describedby="Fig2" src="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig2_HTML.png" alt="figure 2" loading="lazy" width="685" height="286"></picture></a></div><div class="c-article-section__figure-description" data-test="bottom-caption" id="figure-2-desc"><p>Effects of<b> a</b> ambient humidity and <b>b</b> temperature on virus survival rate (Suman et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Suman R, Javaid M, Haleem A, Vaishya R, Bahl S, Nandan D (2020) Sustainability of coronavirus on different surfaces. J Clin Exp Hepatol 10:386–390. 
 https://doi.org/10.1016/j.jceh.2020.04.020
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR39" id="ref-link-section-d38942026e1171">2020</a>)</p></div></div><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="article-link" data-track="click" data-track-label="button" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/2" data-track-dest="link:Figure2 Full size image" aria-label="Full size image figure 2" rel="nofollow"><span>Full size image</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div><p>In closed environments, pH has only a minimal effect on enveloped virus (SARS-CoV-2). Generally, enveloped viruses prefer low-pH environments. An alkaline environment is harmful to enveloped virus (SARS-CoV-2) (Phan et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2019" title="Phan LT, Maita D, Mortiz DC, Weber R, Fritzen-Pedicini C, Bleasdale SC, Jones RM, CDC Prevention Epicenter Program (2019) Personal protective equipment doffing practices of healthcare workers. J Occup Environ Hyg 16(8):575–581. 
 https://doi.org/10.1080/15459624.2019.1628350
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR29" id="ref-link-section-d38942026e1185">2019</a>). The human stomach and gastrointestinal (GI) tract are acidic, which helps enveloped virus (SARS-CoV-2) to replicate in these organs. After replicating in large quantities, enveloped virus (SARS-CoV-2) passes out of the body through the feces and contaminates the environment. Contaminated surfaces play a role in disease transmission. Enveloped virus (SARS-CoV-2) can live on contaminated surfaces, and they can be transferred from those surfaces onto hands or other protective clothing, spreading infection. If the adsorption rate of the surface is high, enveloped virus (SARS-CoV-2) will remain viable there for a longer period of time (a week or, in some cases, even a month) (Lessler et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2009" title="Lessler J, Reich NG, Brookmeyer R, Perl TM, Nelson KE, Cummings DA (2009) Incubation periods of acute respiratory viral infections: a systematic review. Lancet Infect Dis 9(5):291–300. 
 https://doi.org/10.1016/S1473-3099(09)70069-6
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR22" id="ref-link-section-d38942026e1188">2009</a>). Thus, the adsorption capacity of the surface is directly proportional to enveloped virus (SARS-CoV-2) survival rate. The existence of a microbial population negatively affects enveloped virus (SARS-CoV-2) survival rate. If viruses and microbial populations are present on the same surface they compete for nutrients, so enveloped virus (SARS-CoV-2) replication rate becomes very low (Stowell et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2012" title="Stowell JD, Forlin-Passoni D, Din E et al (2012) Cytomegalovirus survival on common environmental surfaces: opportunities for viral transmission. J Infect Dis 205(2):211–214. 
 https://doi.org/10.1093/infdis/jir722
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR38" id="ref-link-section-d38942026e1191">2012</a>). Other factors that promote viral inactivation include the presence of disinfectants, chlorine, a high pH, particular surface properties, and air circulation. Data on the effects of these factors on virus viability are extremely helpful when planning and implementing appropriate steps for controlling and preventing viral diseases. In fact, if at all possible, controlling these environmental factors is an excellent alternative approach to controlling viral infections.</p><p>As different surfaces exert different environmental stresses, viruses are not equally as viable on all surfaces. As shown in Fig. <a data-track="click" data-track-label="link" data-track-action="figure anchor" href="/article/10.1007/s41207-021-00251-w#Fig3">3</a>, coronavirus can survive on a variety of environmental surfaces for periods ranging from several minutes to several days. The survival rate of enveloped virus (SARS-CoV-2) is highest in culture media: it can be transferred from culture media after 4–5 days. Most cultures are maintained at low temperatures, and the presence of abundant nutrients helps enveloped virus (SARS-CoV-2) to replicate and survive. Autoclave water is free from microbial populations, and enveloped virus (SARS-CoV-2) survival time in autoclave water is shorter than that in culture media due to the scarcity of nutrients in the water. Enveloped viruses can remain viable in feces for up to 4 days and can be washed off with water. However, enveloped virus (SARS-CoV-2) is less stable in the urine and has a survival time of less than 6 h (Suman et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Suman R, Javaid M, Haleem A, Vaishya R, Bahl S, Nandan D (2020) Sustainability of coronavirus on different surfaces. J Clin Exp Hepatol 10:386–390. 
 https://doi.org/10.1016/j.jceh.2020.04.020
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR39" id="ref-link-section-d38942026e1200">2020</a>; Sagripanti and Lytle <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Sagripanti J-L, Lytle CD (2020) Estimated inactivation of coronaviruses by solar radiation with special reference to COVID-19. Photochem Photobiol 96:731–737. 
 https://doi.org/10.1111/php.13293
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR36" id="ref-link-section-d38942026e1203">2020</a>; Casanova et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2010c" title="Casanova LM, Jeon S, Rutala WA, Weber DJ, Sobsey MD (2010c) Effects of air temperature and relative humidity on coronavirus survival on surfaces. Appl Environ Microbiol 76(9):2712–2717. 
 https://doi.org/10.1128/AEM.02291-09
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR7" id="ref-link-section-d38942026e1206">2010c</a>; Selcuk et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2021" title="Selcuk M, Gormus S, Guven M (2021) Impact of weather parameters and population density on the COVID-19 transmission: evidence from 81 provinces of Turkey. Earth Syst Environ 5:87–100. 
 https://doi.org/10.1007/s41748-020-00197-z
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR37" id="ref-link-section-d38942026e1209">2021</a>; Al-Kindi et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Al-Kindi KM, Alkharusi A, Alshukaili D et al (2020) Spatiotemporal assessment of COVID-19 spread over Oman using GIS techniques. Earth Syst Environ 4:797–811. 
 https://doi.org/10.1007/s41748-020-00194-2
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR1" id="ref-link-section-d38942026e1213">2020</a>). Enveloped virus (SARS-CoV-2) can also be transmitted through nonporous materials such as glass, plastic, and steel, as well as through porous materials such as cloth. Air humidity, sunlight, and the rate of surface absorption affect the survival time of enveloped virus (SARS-CoV-2) in porous and nonporous substances, as discussed below.</p><div class="c-article-section__figure js-c-reading-companion-figures-item" data-test="figure" data-container-section="figure" id="figure-3" data-title="Fig. 3"><figure><figcaption><b id="Fig3" class="c-article-section__figure-caption" data-test="figure-caption-text">Fig. 3</b></figcaption><div class="c-article-section__figure-content"><div class="c-article-section__figure-item"><a class="c-article-section__figure-link" data-test="img-link" data-track="click" data-track-label="image" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/3" rel="nofollow"><picture><source type="image/webp" srcset="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig3_HTML.png?as=webp"><img aria-describedby="Fig3" src="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig3_HTML.png" alt="figure 3" loading="lazy" width="685" height="326"></picture></a></div><div class="c-article-section__figure-description" data-test="bottom-caption" id="figure-3-desc"><p>SARS-CoV-2 survival times on different environmental surfaces (Suman et al. <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Suman R, Javaid M, Haleem A, Vaishya R, Bahl S, Nandan D (2020) Sustainability of coronavirus on different surfaces. J Clin Exp Hepatol 10:386–390. 
 https://doi.org/10.1016/j.jceh.2020.04.020
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR39" id="ref-link-section-d38942026e1226">2020</a>)</p></div></div><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="article-link" data-track="click" data-track-label="button" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/3" data-track-dest="link:Figure3 Full size image" aria-label="Full size image figure 3" rel="nofollow"><span>Full size image</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div></div></div></section><section data-title="Methods"><div class="c-article-section" id="Sec02-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Sec02">Methods</h2><div class="c-article-section__content" id="Sec02-content"><p>The SARS coronavirus pathogen does not always stay in the respiratory system once it is established in the human body. For example, some important ways that enveloped virus (SARS-CoV-2) can infect wastewater and groundwater are via patient feces, open-air landfills, and contaminated materials that are left in the environment during rainfall; these contamination routes are crucial to understanding COVID-19 diffusion (Islam <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Islam A (2020) Use of PPE in response of coronavirus (COVID-19): a smart solution to global economic challenges? 
 https://doi.org/10.13140/RG.2.2.30872.34568
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR17" id="ref-link-section-d38942026e1245">2020</a>).</p><p>To predict the likelihood of SARS-CoV-2 dispersion into soil through virus-contaminated water, a model of virus diffusion through a layered soil sample was implemented. In this model, water is ponded by a ring on the soil surface. Enveloped virus (SARS-CoV-2) is present in the water puddle, and is transported by the water through the dry soil (Fig. <a data-track="click" data-track-label="link" data-track-action="figure anchor" href="/article/10.1007/s41207-021-00251-w#Fig4">4</a>). The soil is represented by three layers. The top layer is slightly less permeable than those below. The water moves from the bottom of the ring into the soil. The water level in the ring is known, as is the initial distribution of pressure heads in the soil. There is no flow through the vertical walls or the air–soil interface. The porosities (given as volume fractions) of the three layers were considered to be 0.285, 0.348, and 0.403, respectively, starting from the bottom. The soil was considered to be virus-free initially. Enveloped virus (SARS-CoV-2) moves with the water from the pond into the soil at a constant concentration. The model assumes that the vertical axis through the center of the puddle is a line of 2D symmetry. Solutes can freely leave the soil column with the fluid flow through the other boundaries. This problem was modeled and the solute transport was tracked for 20 days.</p><div class="c-article-section__figure js-c-reading-companion-figures-item" data-test="figure" data-container-section="figure" id="figure-4" data-title="Fig. 4"><figure><figcaption><b id="Fig4" class="c-article-section__figure-caption" data-test="figure-caption-text">Fig. 4</b></figcaption><div class="c-article-section__figure-content"><div class="c-article-section__figure-item"><a class="c-article-section__figure-link" data-test="img-link" data-track="click" data-track-label="image" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/4" rel="nofollow"><picture><img aria-describedby="Fig4" src="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig4_HTML.png" alt="figure 4" loading="lazy" width="685" height="845"></picture></a></div><div class="c-article-section__figure-description" data-test="bottom-caption" id="figure-4-desc"><p>Geometry of the puddle ring and the permeable soil layers that were utilized to model virus diffusion through a layered soil sample</p></div></div><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="article-link" data-track="click" data-track-label="button" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/4" data-track-dest="link:Figure4 Full size image" aria-label="Full size image figure 4" rel="nofollow"><span>Full size image</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div></div></div></section><section data-title="Results and discussion: transport through porous media and mathematical modeling development"><div class="c-article-section" id="Sec8-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Sec8">Results and discussion: transport through porous media and mathematical modeling development</h2><div class="c-article-section__content" id="Sec8-content"><p>The Richards equation governs the saturated–unsaturated flow of water in soil. The soil pores are connected to the atmosphere, so it can be assumed that pressure changes in the air do not affect the flow, meaning that the Richards equation is applicable (Oran and Topol <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Oran DP, Topol EJ (2020) Prevalence of asymptomatic SARS-CoV-2 infection. Ann Int Med 173:362–367. 
 https://doi.org/10.7326/M20-3012
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR27" id="ref-link-section-d38942026e1279">2020</a>). In terms of the pressure head, the Richards equation reads</p><div id="Equ1" class="c-article-equation"><div class="c-article-equation__content"><span class="mathjax-tex">$$\left(C+\mathrm{Se}S\right)\frac{\partial {H}_{\mathrm{p}}}{\partial t}+\nabla \cdot \left(-K\nabla \left({H}_{\mathrm{p}}+D\right)\right)=0,$$</span></div><div class="c-article-equation__number"> (1) </div></div><p>where <i>C</i> denotes the specific moisture capacity (m<sup>−1</sup>); Se is the effective saturation of the soil (dimensionless); <i>S</i> is a storage coefficient (m<sup>−1</sup>), which is expressed in terms of<i> θ</i><sub>s</sub> and<i> θ</i><sub>r</sub>: the volume fractions of fluid at saturation and after drainage, respectively; <i>H</i><sub>p</sub> is the pressure head (m), which is proportional to the dependent variable <i>p</i> (Pa); <i>t</i> is the elapsed time; <i>K</i> is the hydraulic conductivity (m/s); and <i>D</i> (m) is the vertical diffusion depth typically, represent in the <i>z</i>-direction and "r" is water paddle radius.</p><p>The most general form of the governing equation for virus transport, which considers the convection and diffusion of a sorbing species in variably saturated soil, can be written as follows:</p><div id="Equ2" class="c-article-equation"><div class="c-article-equation__content"><span class="mathjax-tex">$$\frac{\partial }{\partial t}\left(\theta c\right)+\frac{\partial }{\partial t}\left({\rho }_{\mathrm{b}}{c}_{\mathrm{p}}\right)+{\varvec{u}}\cdot \nabla c+\nabla \cdot (-\theta {D}_{L}\nabla c)=0,$$</span></div><div class="c-article-equation__number"> (2) </div></div><p>where <i>c</i> is enveloped virus (SARS-CoV-2) concentration (PFU/mL); <i>t</i> is the elapsed time; and <i>c</i><sub>p</sub> is the mass of contaminant adsorbed per dry unit weight of solid (mg/kg). In addition, <i>ρ</i><sub>b</sub> is the bulk density (kg/m<sup>3</sup>) and <i>θ</i> is the volume fraction (porosity) of fluid. Thus, the term <i>ρ</i><sub>b</sub><i>c</i><sub>p</sub> is the mass of contaminant attached to the soil. It is worth noting that reaction rate terms were omitted from this preliminary model.</p><p>All of the physical and transport proprieties of soil were fixed in accordance with their literature values (Oran and Topol <a data-track="click" data-track-action="reference anchor" data-track-label="link" data-test="citation-ref" aria-label="Reference 2020" title="Oran DP, Topol EJ (2020) Prevalence of asymptomatic SARS-CoV-2 infection. Ann Int Med 173:362–367. 
 https://doi.org/10.7326/M20-3012
 
 " href="/article/10.1007/s41207-021-00251-w#ref-CR27" id="ref-link-section-d38942026e1576">2020</a>). Enveloped virus (SARS-CoV-2) concentration in the water puddle was considered to be 1 PFU/mL, and the diffusion coefficient of the liquid phase was 3.74 × 10<sup>−3</sup> m<sup>2</sup>/day. Other physical and transport properties are not reported here for the sake of brevity. Different upper soil layer porosities were also analyzed.</p><p>The finite element (FEM) method was used when performing the modeling, which was implemented in COMSOL Multiphysics 5.5. The three soil layers were discretized into a total of 7098 mapped mesh elements with an average element quality of about 0.9993, leading to 35,999 degrees of freedom. The mesh used provided adequate spatial resolution for the system under study. The solution was independent of the grid size, even with further refinements. On an i7-10750 hexa-core processor computer (16 GB DDR4 RAM) running under Windows 10, a typical parametric sweep simulation was completed in about 36 min.</p><p>To aid understanding of the model simulation, Fig. <a data-track="click" data-track-label="link" data-track-action="figure anchor" href="/article/10.1007/s41207-021-00251-w#Fig5">5</a> presents the diffusion of the polluted water into the 3D model constructed through 3D revolution of the corresponding vertically sliced soil.</p><div class="c-article-section__figure js-c-reading-companion-figures-item" data-test="figure" data-container-section="figure" id="figure-5" data-title="Fig. 5"><figure><figcaption><b id="Fig5" class="c-article-section__figure-caption" data-test="figure-caption-text">Fig. 5</b></figcaption><div class="c-article-section__figure-content"><div class="c-article-section__figure-item"><a class="c-article-section__figure-link" data-test="img-link" data-track="click" data-track-label="image" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/5" rel="nofollow"><picture><source type="image/webp" srcset="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig5_HTML.png?as=webp"><img aria-describedby="Fig5" src="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig5_HTML.png" alt="figure 5" loading="lazy" width="685" height="447"></picture></a></div><div class="c-article-section__figure-description" data-test="bottom-caption" id="figure-5-desc"><p>3D model of polluted water transport through porous media</p></div></div><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="article-link" data-track="click" data-track-label="button" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/5" data-track-dest="link:Figure5 Full size image" aria-label="Full size image figure 5" rel="nofollow"><span>Full size image</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div><p>Plots showing the time evolution of the distribution of enveloped virus (SARS-CoV-2) considered in 3 soil sections at 0, 2, 5, 10, 15, and 20 days are reported in Fig. <a data-track="click" data-track-label="link" data-track-action="figure anchor" href="/article/10.1007/s41207-021-00251-w#Fig6">6</a>. In the plots, enveloped virus (SARS-CoV-2) concentrations (in PFU/mL) are normalized to enveloped virus (SARS-CoV-2) concentration in the water pond. Progressive contamination of an increasing proportion of the soil in the second section was observed over the course of 60 h. It is worth mentioning that, in its present form, the model does not consider the decay in virus activity (which could be expressed, for instance, in terms of a decay rate) over time. However, that can easily be included in the model when more detailed information on SARS-COV-2 activity becomes available.</p><div class="c-article-section__figure js-c-reading-companion-figures-item" data-test="figure" data-container-section="figure" id="figure-6" data-title="Fig. 6"><figure><figcaption><b id="Fig6" class="c-article-section__figure-caption" data-test="figure-caption-text">Fig. 6</b></figcaption><div class="c-article-section__figure-content"><div class="c-article-section__figure-item"><a class="c-article-section__figure-link" data-test="img-link" data-track="click" data-track-label="image" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/6" rel="nofollow"><picture><source type="image/webp" srcset="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig6_HTML.png?as=webp"><img aria-describedby="Fig6" src="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig6_HTML.png" alt="figure 6" loading="lazy" width="685" height="382"></picture></a></div><div class="c-article-section__figure-description" data-test="bottom-caption" id="figure-6-desc"><p>Distribution and streamlines of coronavirus at different times in the three soil sections</p></div></div><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="article-link" data-track="click" data-track-label="button" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/6" data-track-dest="link:Figure6 Full size image" aria-label="Full size image figure 6" rel="nofollow"><span>Full size image</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div><p>The evolution of the coronavirus contamination of the soil and the evolution of enveloped virus (SARS-CoV-2) transport streamlines were examined. The third layer (section) only became contaminated after a long period. Additionally, the influence of the upper layer porosity was investigated by performing a parametric sweep analysis using a coefficient ranging from 10% to 190% of the original porosity. The temporal variation in enveloped virus (SARS-CoV-2) concentration at a probe point in the middle layer was derived for various upper layer porosities. The position of this probe point (depth = − 1 m, <i>r</i> = 0.4 m) is shown in Fig. <a data-track="click" data-track-label="link" data-track-action="figure anchor" href="/article/10.1007/s41207-021-00251-w#Fig7">7</a>, and plots of the parametric concentration at that point over time for different upper layer porosities are reported in Fig. <a data-track="click" data-track-label="link" data-track-action="figure anchor" href="/article/10.1007/s41207-021-00251-w#Fig8">8</a>.</p><div class="c-article-section__figure js-c-reading-companion-figures-item" data-test="figure" data-container-section="figure" id="figure-7" data-title="Fig. 7"><figure><figcaption><b id="Fig7" class="c-article-section__figure-caption" data-test="figure-caption-text">Fig. 7</b></figcaption><div class="c-article-section__figure-content"><div class="c-article-section__figure-item"><a class="c-article-section__figure-link" data-test="img-link" data-track="click" data-track-label="image" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/7" rel="nofollow"><picture><source type="image/webp" srcset="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig7_HTML.png?as=webp"><img aria-describedby="Fig7" src="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig7_HTML.png" alt="figure 7" loading="lazy" width="685" height="608"></picture></a></div><div class="c-article-section__figure-description" data-test="bottom-caption" id="figure-7-desc"><p>Position of the probe point in the middle layer</p></div></div><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="article-link" data-track="click" data-track-label="button" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/7" data-track-dest="link:Figure7 Full size image" aria-label="Full size image figure 7" rel="nofollow"><span>Full size image</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div><div class="c-article-section__figure js-c-reading-companion-figures-item" data-test="figure" data-container-section="figure" id="figure-8" data-title="Fig. 8"><figure><figcaption><b id="Fig8" class="c-article-section__figure-caption" data-test="figure-caption-text">Fig. 8</b></figcaption><div class="c-article-section__figure-content"><div class="c-article-section__figure-item"><a class="c-article-section__figure-link" data-test="img-link" data-track="click" data-track-label="image" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/8" rel="nofollow"><picture><source type="image/webp" srcset="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig8_HTML.png?as=webp"><img aria-describedby="Fig8" src="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig8_HTML.png" alt="figure 8" loading="lazy" width="685" height="359"></picture></a></div><div class="c-article-section__figure-description" data-test="bottom-caption" id="figure-8-desc"><p>Temporal evolution of enveloped virus (SARS-CoV-2) concentration at the probe point as a function of the upper layer porosity coefficient</p></div></div><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="article-link" data-track="click" data-track-label="button" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/8" data-track-dest="link:Figure8 Full size image" aria-label="Full size image figure 8" rel="nofollow"><span>Full size image</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div><p>The parametric graphs show that contamination is retarded as the upper layer porosity is increased. This suggests that the flow is mostly influenced by the frictional resistance within the pores and that the pressure gradient is the major driving force. The contamination of the middle layer at a depth of 1 m after 8 days was analyzed. The average concentration in the middle layer at <i>r</i> < 3 m was also investigated, and is reported in Fig. <a data-track="click" data-track-label="link" data-track-action="figure anchor" href="/article/10.1007/s41207-021-00251-w#Fig9">9</a>.</p><div class="c-article-section__figure js-c-reading-companion-figures-item" data-test="figure" data-container-section="figure" id="figure-9" data-title="Fig. 9"><figure><figcaption><b id="Fig9" class="c-article-section__figure-caption" data-test="figure-caption-text">Fig. 9</b></figcaption><div class="c-article-section__figure-content"><div class="c-article-section__figure-item"><a class="c-article-section__figure-link" data-test="img-link" data-track="click" data-track-label="image" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/9" rel="nofollow"><picture><source type="image/webp" srcset="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig9_HTML.png?as=webp"><img aria-describedby="Fig9" src="//media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs41207-021-00251-w/MediaObjects/41207_2021_251_Fig9_HTML.png" alt="figure 9" loading="lazy" width="685" height="372"></picture></a></div><div class="c-article-section__figure-description" data-test="bottom-caption" id="figure-9-desc"><p>Temporal evolution of the average virus concentration in the middle layer at <i>r</i> < 3 m as a function of the upper layer porosity coefficient</p></div></div><div class="u-text-right u-hide-print"><a class="c-article__pill-button" data-test="article-link" data-track="click" data-track-label="button" data-track-action="view figure" href="/article/10.1007/s41207-021-00251-w/figures/9" data-track-dest="link:Figure9 Full size image" aria-label="Full size image figure 9" rel="nofollow"><span>Full size image</span><svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-chevron-right-small"></use></svg></a></div></figure></div><p>In a limited area of the selected soil section, the contamination was seen to be limited to a maximum of 0.1 PFU/mL after 20 days of contaminated water drainage.</p><p>It should be noted that the results presented for this model are from a preliminary investigation. More detailed information on the decay rate of enveloped virus (SARS-CoV-2), detailed diffusion data, and other physical quantities will be updated and included in the model as soon as more information on the SARS-CoV-2 virus is available in the literature. Also, we considered that enveloped virus (SARS-CoV-2)-contaminated water in our model was tap water or fresh water, not wastewater. Wastewater contains residual wastes that could affect the diffusion of enveloped virus (SARS-CoV-2) into the soil. To account for the effects of waterwater components on virus diffusion through the soil in our model, we require more detailed information on the physical and/or chemical interaction mechanisms between enveloped virus (SARS-CoV-2) and other water contaminants to be published in the literature.</p></div></div></section><section data-title="Conclusions"><div class="c-article-section" id="Sec9-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Sec9">Conclusions</h2><div class="c-article-section__content" id="Sec9-content"><p>In this brief review and investigation, we have highlighted the risks of uncontrolled personal protective equipment disposal and the mechanism of virus transmission from contaminated surfaces to humans and groundwater. Considering the risk factors involved, PPE should not be reused without proper disinfection. PPE should be worn and removed according to the recommendations of the CDC and WHO, as this should reduce the risk of cross-contamination. PPE should be changed and disinfected at regular intervals (after about 8 h of continuous utilization). Due to the shortage of PPE caused by the current COVID-19 pandemic, there is a strong drive around the world to reuse PPE. However, if the reused PPE is not properly disinfected, enveloped viruses such as SARS-CoV-2 can spread across its surface. All medical wastes, including defective PPE components, should be discarded in designated appropriate containers and disposed of in landfills. It is also known that viruses can diffuse through porous soil, eventually contaminating groundwater. Proper treatment of enveloped viruses is absolutely necessary to reduce virus transmission and contamination of groundwater sources, even in arid areas. The agencies responsible for the proper disposal of used PPE must ensure that this waste material does not pollute the environment. Enveloped virus (SARS-CoV-2) transport model presented in this paper can easily be applied to other enveloped viruses if relevant chemical and physical transport properties are known. We have presented only the main results of our model and simulations here. More analytical research is necessary to determine all of the causes of infections from enveloped viruses and their transmission pathways, as this should enable the creation of adequate guidelines and safety protocols that will prevent their spread and effectively control infections.</p></div></div></section> </div> <div id="MagazineFulltextArticleBodySuffix"><section aria-labelledby="Bib1" data-title="References"><div class="c-article-section" id="Bib1-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Bib1">References</h2><div class="c-article-section__content" id="Bib1-content"><div data-container-section="references"><ul class="c-article-references" data-track-component="outbound reference" data-track-context="references section"><li class="c-article-references__item js-c-reading-companion-references-item"><p class="c-article-references__text" id="ref-CR1">Al-Kindi KM, Alkharusi A, Alshukaili D et al (2020) Spatiotemporal assessment of COVID-19 spread over Oman using GIS techniques. 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UP acknowledges CONACyT, Mexico, for financial support through research grant # A1-S-26720.</p></div></div></section><section data-title="Funding"><div class="c-article-section" id="Fun-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="Fun">Funding</h2><div class="c-article-section__content" id="Fun-content"><p>Open access funding provided by Università della Calabria within the CRUI-CARE Agreement.. </p></div></div></section><section aria-labelledby="author-information" data-title="Author information"><div class="c-article-section" id="author-information-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="author-information">Author information</h2><div class="c-article-section__content" id="author-information-content"><h3 class="c-article__sub-heading" id="affiliations">Authors and Affiliations</h3><ol class="c-article-author-affiliation__list"><li id="Aff1"><p class="c-article-author-affiliation__address">Laboratory of Transport Phenomena and Biotechnology, Department of D.I.M.E.S, University of Calabria, Via- P. Bucci, Cubo-42a, 87036, Rende, CS, Italy</p><p class="c-article-author-affiliation__authors-list">Francesco Petrosino, Debolina Mukherjee, Gerardo Coppola, Maria Teresa Gaudio, Stefano Curcio, Vincenza Calabro & Sudip Chakraborty</p></li><li id="Aff2"><p class="c-article-author-affiliation__address">Department of Industrial Engineering, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, SA, Italy</p><p class="c-article-author-affiliation__authors-list">Francesco Petrosino & Francesco Marra</p></li><li id="Aff3"><p class="c-article-author-affiliation__address">Department of Sustainable Development, Environmental Science and Engineering, KTH Royal Institute of Technology, Teknikringen 10B, 10044, Stockholm, Sweden</p><p class="c-article-author-affiliation__authors-list">Prosun Bhattacharya</p></li><li id="Aff4"><p class="c-article-author-affiliation__address">Instituto de Física, Benemérita Universidad Autónoma de Puebla, Apdo. 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