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data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Sadržaj</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">sakrij</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Početak</div> </a> </li> <li id="toc-Funkcija" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Funkcija"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Funkcija</span> </div> </a> <ul id="toc-Funkcija-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Ciljne_ćelija" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Ciljne_ćelija"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Ciljne ćelija</span> </div> </a> <ul id="toc-Ciljne_ćelija-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Klinički_značaj" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Klinički_značaj"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Klinički značaj</span> </div> </a> <ul id="toc-Klinički_značaj-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Nomenklatura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Nomenklatura"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Nomenklatura</span> </div> </a> <ul id="toc-Nomenklatura-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Povezano" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Povezano"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Povezano</span> </div> </a> <ul id="toc-Povezano-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reference" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Reference"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Reference</span> </div> </a> <ul id="toc-Reference-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Literatura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Literatura"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Literatura</span> </div> </a> <ul id="toc-Literatura-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Spoljašnje_veze" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Spoljašnje_veze"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>Spoljašnje veze</span> </div> </a> <ul id="toc-Spoljašnje_veze-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Sadržaj" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Prikaži/sakrij sadržaj" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Prikaži/sakrij sadržaj</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading" lang="sh-Latn" dir="ltr"><span class="mw-page-title-main">Interleukin 8</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Prijedi na druge jezične varijante članka. Dostupno je na 22 jezika" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-22" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">22 jezika</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A5%D9%86%D8%AA%D8%B1%D9%84%D9%88%D9%83%D9%8A%D9%86_8" title="إنترلوكين 8 — Arapski" lang="ar" hreflang="ar" data-title="إنترلوكين 8" data-language-autonym="العربية" data-language-local-name="Arapski" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Interleukin_8" title="Interleukin 8 — Bosanski" lang="bs" hreflang="bs" data-title="Interleukin 8" data-language-autonym="Bosanski" data-language-local-name="Bosanski" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Interleukin_8" title="Interleukin 8 — Češki" lang="cs" hreflang="cs" data-title="Interleukin 8" data-language-autonym="Čeština" data-language-local-name="Češki" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/CXCL8" title="CXCL8 — Velški" lang="cy" hreflang="cy" data-title="CXCL8" data-language-autonym="Cymraeg" data-language-local-name="Velški" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Interleukin-8" title="Interleukin-8 — Nemački" lang="de" hreflang="de" data-title="Interleukin-8" data-language-autonym="Deutsch" data-language-local-name="Nemački" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Interleukin_8" title="Interleukin 8 — Engleski" lang="en" hreflang="en" data-title="Interleukin 8" data-language-autonym="English" data-language-local-name="Engleski" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Interleucina-8" title="Interleucina-8 — Španski" lang="es" hreflang="es" data-title="Interleucina-8" data-language-autonym="Español" data-language-local-name="Španski" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A7%DB%8C%D9%86%D8%AA%D8%B1%D9%84%D9%88%DA%A9%DB%8C%D9%86_%DB%B8" title="اینترلوکین ۸ — Persijski" lang="fa" hreflang="fa" data-title="اینترلوکین ۸" data-language-autonym="فارسی" data-language-local-name="Persijski" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Interleukine_8" title="Interleukine 8 — Francuski" lang="fr" hreflang="fr" data-title="Interleukine 8" data-language-autonym="Français" data-language-local-name="Francuski" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Interleucina_8" title="Interleucina 8 — Galski" lang="gl" hreflang="gl" data-title="Interleucina 8" data-language-autonym="Galego" data-language-local-name="Galski" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Interleukin-8" title="Interleukin-8 — Indonezijski" lang="id" hreflang="id" data-title="Interleukin-8" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonezijski" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Interleuchina_8" title="Interleuchina 8 — Italijanski" lang="it" hreflang="it" data-title="Interleuchina 8" data-language-autonym="Italiano" data-language-local-name="Italijanski" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%A4%E3%83%B3%E3%82%BF%E3%83%BC%E3%83%AD%E3%82%A4%E3%82%AD%E3%83%B3-8" title="インターロイキン-8 — Japanski" lang="ja" hreflang="ja" data-title="インターロイキン-8" data-language-autonym="日本語" data-language-local-name="Japanski" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/IL-8" title="IL-8 — Holandski" lang="nl" hreflang="nl" data-title="IL-8" data-language-autonym="Nederlands" data-language-local-name="Holandski" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Interleukina_8" title="Interleukina 8 — Poljski" lang="pl" hreflang="pl" data-title="Interleukina 8" data-language-autonym="Polski" data-language-local-name="Poljski" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Interleucina_8" title="Interleucina 8 — Portugalski" lang="pt" hreflang="pt" data-title="Interleucina 8" data-language-autonym="Português" data-language-local-name="Portugalski" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D0%B9%D0%BA%D0%B8%D0%BD_8" title="Интерлейкин 8 — Ruski" lang="ru" hreflang="ru" data-title="Интерлейкин 8" data-language-autonym="Русский" data-language-local-name="Ruski" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Interleuk%C3%ADn_8" title="Interleukín 8 — Slovački" lang="sk" hreflang="sk" data-title="Interleukín 8" data-language-autonym="Slovenčina" data-language-local-name="Slovački" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_8" title="Интерлеукин 8 — Srpski" lang="sr" hreflang="sr" data-title="Интерлеукин 8" data-language-autonym="Српски / srpski" data-language-local-name="Srpski" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%86%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D0%B9%D0%BA%D1%96%D0%BD-8" title="Інтерлейкін-8 — Ukrajinski" lang="uk" hreflang="uk" data-title="Інтерлейкін-8" data-language-autonym="Українська" data-language-local-name="Ukrajinski" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Interleukin_8" title="Interleukin 8 — Vijetnamski" lang="vi" hreflang="vi" data-title="Interleukin 8" data-language-autonym="Tiếng Việt" data-language-local-name="Vijetnamski" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E7%99%BD%E7%BB%86%E8%83%9E%E4%BB%8B%E7%B4%A0-8" title="白细胞介素-8 — Kineski" lang="zh" hreflang="zh" data-title="白细胞介素-8" data-language-autonym="中文" data-language-local-name="Kineski" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q421859#sitelinks-wikipedia" title="Uredi međujezične poveznice" class="wbc-editpage">Uredi veze</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Imenski prostori"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" lang="sh-Latn" dir="ltr"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Interleukin_8" title="Vidi stranicu sadržaja [c]" accesskey="c"><span>Stranica</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Razgovor:Interleukin_8" rel="discussion" title="Razgovarajte o sadržini ove stranice [t]" accesskey="t"><span>Razgovor</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown " lang="sh-Latn" dir="ltr"> <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Promijeni jezičnu varijantu" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Latinica</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants" lang="sh-Latn" dir="ltr"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-varlang-0" class="selected ca-variants-sh-Latn mw-list-item"><a href="/w/index.php?title=Interleukin_8&variant=sh-latn" lang="sh-Latn" hreflang="sh-Latn"><span>Latinica</span></a></li><li id="ca-varlang-1" class="ca-variants-sh-Cyrl mw-list-item"><a href="/w/index.php?title=Interleukin_8&variant=sh-cyrl" lang="sh-Cyrl" hreflang="sh-Cyrl"><span>Ћирилица</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Teme"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" lang="sh-Latn" dir="ltr"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Interleukin_8"><span>Prikaži</span></a></li><li id="ca-ve-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Interleukin_8&veaction=edit" title="Uredite ovu stranicu [v]" accesskey="v"><span>Uredi</span></a></li><li id="ca-edit" class="collapsible vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Interleukin_8&action=edit" title="Uredite izvorni kod ove stranice [e]" accesskey="e"><span>Uredi kod</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Interleukin_8&action=history" title="Pogledajte prethodne verzije ove stranice [h]" accesskey="h"><span>Historija</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Pomagala"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Alatke" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Alatke</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Alati</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">sakrij</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="Više mogućnosti" lang="sh-Latn" dir="ltr"> <div class="vector-menu-heading"> Radnje </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Interleukin_8"><span>Prikaži</span></a></li><li id="ca-more-ve-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Interleukin_8&veaction=edit" title="Uredite ovu stranicu [v]" accesskey="v"><span>Uredi</span></a></li><li id="ca-more-edit" class="collapsible vector-more-collapsible-item mw-list-item"><a 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</div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" lang="sh-Latn" dir="ltr"> <div class="vector-menu-heading"> Na drugim projektima </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q421859" title="Pogledajte povezanu stavku u skladištu podataka [g]" accesskey="g"><span>Stavka na Wikipodacima</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Pomagala"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Izgled"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Izgled</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">sakrij</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Izvor: Wikipedija</div> </div> <div id="contentSub" lang="sh-Latn" dir="ltr"><div id="mw-content-subtitle" lang="sh-Latn" dir="ltr"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="sh-Latn" dir="ltr"><table align="right" border="0" style="background:#fff; width:280px;"> <tbody><tr> <td align="right"><span class="plainlinks"><a class="external text" href="https://sh.wikipedia.org/w/index.php?title=%C5%A0ablon:PBB/3576&action=edit">edit</a></span> </td></tr></tbody></table><table class="infobox" cellspacing="5" style="width: 22em; text-align: left; font-size: 88%; line-height: 1.5em;"><tbody><tr class=""><th colspan="4" style="text-align:center; text-align:center; font-size:125%; font-weight:bold;">Interleukin 8</th></tr><tr class=""><td colspan="4" class="" style="text-align:center;"><span class="mw-image-border" typeof="mw:File"><a href="/wiki/Datoteka:IL8_Solution_Structure.rsh.png" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/IL8_Solution_Structure.rsh.png/250px-IL8_Solution_Structure.rsh.png" decoding="async" width="250" height="208" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/IL8_Solution_Structure.rsh.png/375px-IL8_Solution_Structure.rsh.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f6/IL8_Solution_Structure.rsh.png/500px-IL8_Solution_Structure.rsh.png 2x" data-file-width="900" data-file-height="750" /></a></span><br /><span style=""><a href="/wiki/Protein_Data_Bank" class="mw-redirect" title="Protein Data Bank">PDB</a> prikaz baziran na <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IL8">1IL8</a></span>.</span></td></tr><tr class=""><th colspan="4" style="text-align:center; background-color: #ddd">Dostupne strukture</th></tr><tr class=""><td colspan="4" class="" style="text-align:center; background-color: #eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1icw">1icw</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ikl">1ikl</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ikm">1ikm</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1il8">1il8</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ilp">1ilp</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ilq">1ilq</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1qe6">1qe6</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2il8">2il8</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3il8">3il8</a></span></td></tr><tr class=""><th colspan="4" style="text-align:center; background-color: #ddd">Identifikatori</th></tr><tr class=""><th style="background-color: #c3fdb8"><a href="/wiki/Organizacija_za_ljudski_genom" title="Organizacija za ljudski genom">Simboli</a></th><td colspan="3" class="" style="background-color: #eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=6025">IL8</a>; 3-10C; AMCF-I; CXCL8; GCP-1; GCP1; K60; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; SCYB8; TSG-1; b-ENAP</span></td></tr><tr class=""><th style="background-color: #c3fdb8">Vanjski ID</th><td colspan="3" class="" style="background-color: #eee"><span class="plainlinks"><a href="/wiki/Mendelovsko_nasle%C4%91ivanje_kod_%C4%8Doveka" class="mw-redirect" title="Mendelovsko nasleđivanje kod čoveka">OMIM</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=146930">146930 </a></span> <span class="plainlinks"><a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=47937">47937 </a></span> <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=3576">IL8 Gene</a></span></td></tr><tr class=""><td colspan="4" class="" style="text-align:center; background-color: #eee"><table class="collapsible collapsed" style="border: none; padding: 0; margin: 0; width: 100%; text-align: left"> <tbody><tr style="background-color: #ddd; text-align: center"> <th colspan="2"><a href="/wiki/Ontologija_gena" title="Ontologija gena">Ontologija gena</a></th> </tr> <tr> <th style="background-color: #c3fdb8">Molekulska funkcija</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005153">vezivanje za interleukin-8 receptor</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005515">vezivanje za proteine</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0008009">aktivnost hemokina</a></span><br /></td> </tr> <tr> <th style="background-color: #c3fdb8">Ćelijska komponenta</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005576">ekstracelularni region</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005615">ekstracelularni prostor</a></span><br /></td> </tr> <tr> <th style="background-color: #c3fdb8">Biološki proces</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0001525">angiogeneza</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0006928">ćelijska pokretljivost</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0006935">hemotaksa</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0006954">inflamatorni respons</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0006955">imunski respons</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007050">arest ćelijskog ciklusa</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007186">G-protein spregnuti receptor proteinski signalni put</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007242">interćelijska signalizaciona kaskada</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007267">interćelijska signalizacija</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0008285">negativna regulacija ćelijske proliferecije</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0019722">kalcijum-posredovana signalizacija</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0030155">regulacija ćelijske adhezije</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0030593">hemotaksa neutrofila</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0042119">aktivacija neutrofila</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0045091">regulacija replikacije retrovirusnog genoma</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0050930">indukcija pozitivne hemotakse</a></span><br /></td> </tr> </tbody></table></td></tr><tr class=""><th colspan="4" style="text-align:center; background-color: #ddd">Pregled RNK izražavanja</th></tr><tr class=""><td colspan="4" class="" style="text-align:center; background-color: #eee"><span typeof="mw:File"><a href="/wiki/Datoteka:PBB_GE_IL8_211506_s_at.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/a/ae/PBB_GE_IL8_211506_s_at.png/250px-PBB_GE_IL8_211506_s_at.png" decoding="async" width="250" height="132" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/a/ae/PBB_GE_IL8_211506_s_at.png 1.5x" data-file-width="255" data-file-height="135" /></a></span></td></tr><tr class=""><td colspan="4" class="" style="text-align:center; background-color: #eee"><span typeof="mw:File"><a href="/wiki/Datoteka:PBB_GE_IL8_202859_x_at.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/PBB_GE_IL8_202859_x_at.png/250px-PBB_GE_IL8_202859_x_at.png" decoding="async" width="250" height="132" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/d/dd/PBB_GE_IL8_202859_x_at.png 1.5x" data-file-width="255" data-file-height="135" /></a></span></td></tr><tr class=""><td colspan="4" class="" style="text-align:center; background-color: #eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.gnf.org/gene/3576/Dodatni">podaci</a></span></td></tr><tr class=""><th colspan="4" style="text-align:center; background-color: #ddd">Ortolozi</th></tr><tr class="" style=""><th style="background-color: #c3fdb8">Vrsta</th><td class="" style=""><b>Čovek</b></td><td class="" style=""><b>Miš</b></td><td class="" style=""></td></tr><tr class="" style=""><th style="background-color: #c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td class="" style=""><span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=3576&rn=1">3576</a></span></td><td class="" style="">n/a</td><td class="" style=""></td></tr><tr class="" style=""><th style="background-color: #c3fdb8"><a href="/wiki/Ensembl" title="Ensembl">Ensembl</a></th><td class="" style=""><span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000169429;db=core">ENSG00000169429</a></span></td><td class="" style="">n/a</td><td class="" style=""></td></tr><tr class="" style=""><th style="background-color: #c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td class="" style=""><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/P10145">P10145</a></span></td><td class="" style="">n/a</td><td class="" style=""></td></tr><tr class="" style=""><th style="background-color: #c3fdb8">Ref. Sekv. (iRNK)</th><td class="" style=""><span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_000584">NM_000584</a></span></td><td class="" style="">n/a</td><td class="" style=""></td></tr><tr class="" style=""><th style="background-color: #c3fdb8">Ref. Sekv. (protein)</th><td class="" style=""><span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_000575">NP_000575</a></span></td><td class="" style="">n/a</td><td class="" style=""></td></tr><tr class="" style=""><th style="background-color: #c3fdb8">Lokacija (UCSC)</th><td class="" style=""><span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg18&position=chr4:74825139-74828295">Chr 4:<br />74.83 - 74.83 Mb</a></span></td><td class="" style="">n/a</td><td class="" style=""></td></tr><tr class="" style=""><th style="background-color: #c3fdb8"><a href="/wiki/PubMed" title="PubMed">PubMed</a> pretraga</th><td class="" style=""><span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=3576">[1]</a></span></td><td class="" style="">n/a</td><td class="" style=""></td></tr> </tbody></table> <p><b>Interleukin 8</b> (<b>IL-8</b>) je <a href="/wiki/Citokini" class="mw-redirect" title="Citokini">citokin</a> koga proizvode <a href="/wiki/Makrofag" title="Makrofag">makrofage</a> i ćelije drugih tipova kao što su <a href="/wiki/Epitelsko_tkivo" title="Epitelsko tkivo">epitelijalne ćelije</a>. NJega isto tako sintetizuju <a href="/wiki/Endotel" title="Endotel">endotelijalne ćelije</a>, koje skladište IL-8 u njihovim skladišnim mehurima, <a href="/w/index.php?title=Weibel-Palade_tela&action=edit&redlink=1" class="new" title="Weibel-Palade tela (stranica ne postoji)">Weibel-Palade tela</a>.<sup id="cite_ref-pmid9802987_1-0" class="reference"><a href="#cite_note-pmid9802987-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid9802986_2-0" class="reference"><a href="#cite_note-pmid9802986-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Kod ljudi, interleukin 8 je <a href="/wiki/Protein" title="Protein">protein</a> kodiran <i>IL8</i> <a href="/wiki/Gen" title="Gen">genom</a>.<sup id="cite_ref-pmid1967588_3-0" class="reference"><a href="#cite_note-pmid1967588-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> On se izlučuje kroz lanac biohemijskih reakcija. IL-8 je važan posrednik imunih reakcija u odgovoru urođenog imunskog sistema.<sup id="cite_ref-KubyImmunology6th_4-0" class="reference"><a href="#cite_note-KubyImmunology6th-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>Postoji više receptora na površini membrana koji mogu da vežu IL-8. Najčešće studirani tipovi su <a href="/wiki/G_protein_spregnuti_receptori" title="G protein spregnuti receptori">G protein spregnuti</a> <a href="/wiki/Serpentin" title="Serpentin">serpentin</a> receptori <a href="/w/index.php?title=Interleukin_8_receptor,_alfa&action=edit&redlink=1" class="new" title="Interleukin 8 receptor, alfa (stranica ne postoji)">CXCR1</a> i <a href="/w/index.php?title=Interleukin_8_receptor,_beta&action=edit&redlink=1" class="new" title="Interleukin 8 receptor, beta (stranica ne postoji)">CXCR2</a>. Izražavanje i IL-8 afinitet je različit za ova dva receptora (CXCR1 > CXCR2). <a href="/w/index.php?title=Toll-sli%C4%8Dni_receptor&action=edit&redlink=1" class="new" title="Toll-slični receptor (stranica ne postoji)">Toll-slični receptori</a> su receptori urođenog imunskog sistema. Ti receptori prepoznaju antigen obrasce (poput <a href="/wiki/LPS" class="mw-disambig" title="LPS">LPS</a> kod <a href="/wiki/Gram-negativne_bakterije" class="mw-redirect" title="Gram-negativne bakterije">gram negativnih</a> bakterija). </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Funkcija">Funkcija</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interleukin_8&veaction=edit&section=1" title="Uredi odjeljak Funkcija" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Interleukin_8&action=edit&section=1" title="Uredi kôd odjeljka Funkcija"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Protein" title="Protein">Protein</a> kodiran ovim genom je član <a href="/w/index.php?title=CXC&action=edit&redlink=1" class="new" title="CXC (stranica ne postoji)">CXC</a> <a href="/wiki/Hemokin" title="Hemokin">hemokin</a> familije. Ovaj hemokin je jedan od glavnih posrednika inflamatornog procesa. Ovaj hemokin se izlučuje iz nekoliko ćelijskih tipova. On funkcioniše kao hemoatraktant, i one takođe potentan <a href="/wiki/Angiogeneza" title="Angiogeneza">angiogenetski</a> faktor. IL-8 ima oblika: <a href="/wiki/Monomer" title="Monomer">monomer</a> i <a href="/wiki/Homodimer" class="mw-redirect" title="Homodimer">homodimer</a>. Za oba oblika je nađeno da su potentni <a href="/w/index.php?title=CXCR1&action=edit&redlink=1" class="new" title="CXCR1 (stranica ne postoji)">CXCR1</a> i <a href="/w/index.php?title=CXCR2&action=edit&redlink=1" class="new" title="CXCR2 (stranica ne postoji)">CXCR2</a> pobuđivači. Dokazano je da je homodimer potentniji, međutim, <a href="/wiki/Leucin" title="Leucin">Leu25</a> <a href="/wiki/Metilacija" title="Metilacija">metilacija</a> može da blokira aktivnost dimera. Za IL-8 se veruje da igra ulogu u patogenezi <a href="/w/index.php?title=Bronhiolitis&action=edit&redlink=1" class="new" title="Bronhiolitis (stranica ne postoji)">bronhiolitisa</a>, rasprostranjenog oboljenja respiratornog trakta uzrokovanog viralnom infekcijom. Ovaj gen i drugih deset članova <a href="/w/index.php?title=CXC&action=edit&redlink=1" class="new" title="CXC (stranica ne postoji)">CXC</a> hemokin genske familije formiraju hemokinski genski klaster na <a href="/wiki/Hromozom_4" class="mw-redirect" title="Hromozom 4">hromozomu 4</a>.<sup id="cite_ref-pmid1967588_3-1" class="reference"><a href="#cite_note-pmid1967588-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>IL-8 primarna funkcija je indukcija <a href="/wiki/Hemotaksa" title="Hemotaksa">hemotakse</a> u njegovim ciljnim ćelijama (npr. <a href="/wiki/Neutrofil" title="Neutrofil">neutrofilnim</a> <a href="/wiki/Granulocit" class="mw-redirect" title="Granulocit">granulocitima</a>). On učestvuje u neutrofilskoj seriji ćelijsko-fizioloških odgovora neophodnih za migraciju i u njihovoj ciljnoj funkciji, <a href="/wiki/Fagocitoza" title="Fagocitoza">fagocitozi</a>. On takođe ima udela u povećanju intracelularnog <a href="/wiki/Kalcijum" class="mw-redirect" title="Kalcijum">Ca<sup>2+</sup></a>, <a href="/w/index.php?title=Eksocitoza&action=edit&redlink=1" class="new" title="Eksocitoza (stranica ne postoji)">eksocitozi</a> (npr. oslobađanju <a href="/wiki/Histamin" title="Histamin">histamina</a>), <a href="/w/index.php?title=Respiratorno_%C5%A1irenje&action=edit&redlink=1" class="new" title="Respiratorno širenje (stranica ne postoji)">respiratornom širenju</a>. IL-8 može biti izlučen iz bilo koje ćelija sa <a href="/w/index.php?title=Toll-sli%C4%8Dni_receptor&action=edit&redlink=1" class="new" title="Toll-slični receptor (stranica ne postoji)">Toll-sličnim receptorima</a> u okviru urođenog imunog odgovora. Primarna funkcija IL-8 citokina je da regrutuje <a href="/wiki/Neutrofil" title="Neutrofil">neutrofile</a> da fagocitoziraju antigen koji je pobudio antigenski obrazac toll-sličnog receptora. </p> <div class="mw-heading mw-heading2"><h2 id="Ciljne_ćelija"><span id="Ciljne_.C4.87elija"></span>Ciljne ćelija</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interleukin_8&veaction=edit&section=2" title="Uredi odjeljak Ciljne ćelija" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Interleukin_8&action=edit&section=2" title="Uredi kôd odjeljka Ciljne ćelija"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Dok su neutrofilni granulociti primarna meta za IL-8, postoji relativno širok krug ćelija (<a href="/wiki/Endotel" title="Endotel">endotelne ćelije</a>, <a href="/wiki/Makrofag" title="Makrofag">makrofage</a>, <a href="/wiki/Mastocit" title="Mastocit">mast ćelije</a>, <a href="/w/index.php?title=Keratinocit&action=edit&redlink=1" class="new" title="Keratinocit (stranica ne postoji)">keratinociti</a>) koje reaguju na ovaj hemokin. IL-8 <a href="/w/index.php?title=Hemoatraktantska_aktivnost&action=edit&redlink=1" class="new" title="Hemoatraktantska aktivnost (stranica ne postoji)">hemoatraktantska aktivnost</a> u sličnim koncentracijama kao kod kičmenjaka je pokazana i kod <i><a href="/w/index.php?title=Tetrahymena&action=edit&redlink=1" class="new" title="Tetrahymena (stranica ne postoji)">Tetrahymena pyriformis</a></i>, što ukazuje na <a href="/wiki/Filogenetika" class="mw-redirect" title="Filogenetika">filogenetički</a> visoko konzerviranu strukturu i funkciju ovoj hemokina.<sup id="cite_ref-pmid9702410_7-0" class="reference"><a href="#cite_note-pmid9702410-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Klinički_značaj"><span id="Klini.C4.8Dki_zna.C4.8Daj"></span>Klinički značaj</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interleukin_8&veaction=edit&section=3" title="Uredi odjeljak Klinički značaj" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Interleukin_8&action=edit&section=3" title="Uredi kôd odjeljka Klinički značaj"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Interleukin-8 je često asociran sa inflamacijom. Na primer, bilo je objavljeno da proinflamatorni medijator <a href="/w/index.php?title=Gingivitis&action=edit&redlink=1" class="new" title="Gingivitis (stranica ne postoji)">gingivitisa</a><sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> i <a href="/wiki/Psorijaza" title="Psorijaza">psorijaze</a>.<sup id="cite_ref-Psoriasis_9-0" class="reference"><a href="#cite_note-Psoriasis-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup>. Činjenica da je interleukin 8 sekrecija povećana sa oksidant stresom, i obrnuto, interleukin 8 uzrokujući regrutovanje inflamatornih ćelija inducira dalje povećanje oksidantskog stresa, čini ovaj citokin ključnim parametrom u lokalizovanoj inflamaciji.<sup id="cite_ref-pmid10477716_10-0" class="reference"><a href="#cite_note-pmid10477716-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p><p>Ako trudnica ima visok nivo interleukina 8, ona ima povišen rizik induciranja <a href="/wiki/Shizofrenija" title="Shizofrenija">shizofrenije</a> u potomstvu.<sup id="cite_ref-pmid15121655_11-0" class="reference"><a href="#cite_note-pmid15121655-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Za visoke nivoe interleukina 8 je pokazano da umanjuju šanse za uspeh tretmana sa <a href="/wiki/Antipsihotici" class="mw-redirect" title="Antipsihotici">antipsihotičkim</a> medikacijama za shizofreniju.<sup id="cite_ref-pmid15291683_12-0" class="reference"><a href="#cite_note-pmid15291683-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Nomenklatura">Nomenklatura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interleukin_8&veaction=edit&section=4" title="Uredi odjeljak Nomenklatura" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Interleukin_8&action=edit&section=4" title="Uredi kôd odjeljka Nomenklatura"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>IL-8 je preimenovan u CXCL8 od strane <a href="/w/index.php?title=Subkomitet_za_hemokinsku_nomenklaturu&action=edit&redlink=1" class="new" title="Subkomitet za hemokinsku nomenklaturu (stranica ne postoji)">Subkomiteta za hemokinsku nomenklaturu</a> koje je deo <a href="/w/index.php?title=Internacionalna_unija_imunolo%C5%A1kih_udru%C5%BEenja&action=edit&redlink=1" class="new" title="Internacionalna unija imunoloških udruženja (stranica ne postoji)">Internacionalne unije imunoloških udruženja</a>,<sup id="cite_ref-pmid12433287_13-0" class="reference"><a href="#cite_note-pmid12433287-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> mada njegovo odobreni <a href="/wiki/Organizacija_za_ljudski_genom" title="Organizacija za ljudski genom">HUGO</a> simbol <a href="/wiki/Gen" title="Gen">gena</a> ostaje <i>IL8</i>. </p> <div class="mw-heading mw-heading2"><h2 id="Povezano">Povezano</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interleukin_8&veaction=edit&section=5" title="Uredi odjeljak Povezano" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Interleukin_8&action=edit&section=5" title="Uredi kôd odjeljka Povezano"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/w/index.php?title=IL8RA&action=edit&redlink=1" class="new" title="IL8RA (stranica ne postoji)">Interleukin 8 receptor, alfa</a></li> <li><a href="/w/index.php?title=IL8RB&action=edit&redlink=1" class="new" title="IL8RB (stranica ne postoji)">Interleukin 8 receptor, beta</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Reference">Reference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interleukin_8&veaction=edit&section=6" title="Uredi odjeljak Reference" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Interleukin_8&action=edit&section=6" title="Uredi kôd odjeljka Reference"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r41556849">.mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width reflist-columns-2"> <ol class="references"> <li id="cite_note-pmid9802987-1"><span class="mw-cite-backlink"><a href="#cite_ref-pmid9802987_1-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Wolff B, Burns AR, Middleton J, Rot A (November 1998). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2212526/">„Endothelial cell "memory" of inflammatory stimulation: human venular endothelial cells store interleukin 8 in Weibel-Palade bodies”</a>. <i>J. Exp. Med.</i> <b>188</b> (9): 1757–62. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1084%2Fjem.188.9.1757">10.1084/jem.188.9.1757</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2212526">2212526</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/9802987">9802987</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Endothelial+cell+%22memory%22+of+inflammatory+stimulation%3A+human+venular+endothelial+cells+store+interleukin+8+in+Weibel-Palade+bodies&rft.jtitle=J.+Exp.+Med.&rft.aulast=Wolff+B%2C+Burns+AR%2C+Middleton+J%2C+Rot+A&rft.au=Wolff+B%2C+Burns+AR%2C+Middleton+J%2C+Rot+A&rft.date=November+1998&rft.volume=188&rft.issue=9&rft.pages=1757%E2%80%9362&rft_id=info:doi/10.1084%2Fjem.188.9.1757&rft_id=info:pmc/2212526&rft_id=info:pmid/9802987&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2212526%2F&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid9802986-2"><span class="mw-cite-backlink"><a href="#cite_ref-pmid9802986_2-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Utgaard JO, Jahnsen FL, Bakka A, Brandtzaeg P, Haraldsen G (November 1998). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2212514/">„Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells”</a>. <i>J. Exp. Med.</i> <b>188</b> (9): 1751–6. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1084%2Fjem.188.9.1751">10.1084/jem.188.9.1751</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2212514">2212514</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/9802986">9802986</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Rapid+secretion+of+prestored+interleukin+8+from+Weibel-Palade+bodies+of+microvascular+endothelial+cells&rft.jtitle=J.+Exp.+Med.&rft.aulast=Utgaard+JO%2C+Jahnsen+FL%2C+Bakka+A%2C+Brandtzaeg+P%2C+Haraldsen+G&rft.au=Utgaard+JO%2C+Jahnsen+FL%2C+Bakka+A%2C+Brandtzaeg+P%2C+Haraldsen+G&rft.date=November+1998&rft.volume=188&rft.issue=9&rft.pages=1751%E2%80%936&rft_id=info:doi/10.1084%2Fjem.188.9.1751&rft_id=info:pmc/2212514&rft_id=info:pmid/9802986&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2212514%2F&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid1967588-3"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-pmid1967588_3-0">3,0</a></sup> <sup><a href="#cite_ref-pmid1967588_3-1">3,1</a></sup></span> <span class="reference-text"><span class="citation Journal">Modi WS, Dean M, Seuanez HN, Mukaida N, Matsushima K, O'Brien SJ (January 1990). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_human-genetics_1990-01_84_2/page/185">„Monocyte-derived neutrophil chemotactic factor (MDNCF/IL-8) resides in a gene cluster along with several other members of the platelet factor 4 gene superfamily”</a>. <i>Hum. Genet.</i> <b>84</b> (2): 185–7. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1007%2FBF00208938">10.1007/BF00208938</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/1967588">1967588</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Monocyte-derived+neutrophil+chemotactic+factor+%28MDNCF%2FIL-8%29+resides+in+a+gene+cluster+along+with+several+other+members+of+the+platelet+factor+4+gene+superfamily&rft.jtitle=Hum.+Genet.&rft.aulast=Modi+WS%2C+Dean+M%2C+Seuanez+HN%2C+Mukaida+N%2C+Matsushima+K%2C+O%27Brien+SJ&rft.au=Modi+WS%2C+Dean+M%2C+Seuanez+HN%2C+Mukaida+N%2C+Matsushima+K%2C+O%27Brien+SJ&rft.date=January+1990&rft.volume=84&rft.issue=2&rft.pages=185%E2%80%937&rft_id=info:doi/10.1007%2FBF00208938&rft_id=info:pmid/1967588&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_human-genetics_1990-01_84_2%2Fpage%2F185&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-KubyImmunology6th-4"><span class="mw-cite-backlink"><a href="#cite_ref-KubyImmunology6th_4-0">↑</a></span> <span class="reference-text"><span class="citation book">Thomas J. Kindt, Richard A. Goldsby, Barbara Anne Osborne, Janis Kuby (2006). <a rel="nofollow" class="external text" href="http://bcs.whfreeman.com/immunology6e/default.asp?s=&n=&i=&v=&o=&ns=0&uid=0&rau=0"><i>Kuby Immunology</i></a> (6 izd.). New York: W H Freeman and company. <a href="/wiki/International_Standard_Book_Number" class="mw-redirect" title="International Standard Book Number">ISBN</a> <a href="/wiki/Posebno:Tra%C5%BEi_ISBN/1-4292-0211-4" title="Posebno:Traži ISBN/1-4292-0211-4">1-4292-0211-4</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Kuby+Immunology&rft.aulast=Thomas+J.+Kindt%2C+Richard+A.+Goldsby%2C+Barbara+Anne+Osborne%2C+Janis+Kuby&rft.au=Thomas+J.+Kindt%2C+Richard+A.+Goldsby%2C+Barbara+Anne+Osborne%2C+Janis+Kuby&rft.date=2006&rft.edition=6&rft.place=New+York&rft.pub=W+H+Freeman+and+company&rft.isbn=1-4292-0211-4&rft_id=http%3A%2F%2Fbcs.whfreeman.com%2Fimmunology6e%2Fdefault.asp%3Fs%3D%26n%3D%26i%3D%26v%3D%26o%3D%26ns%3D0%26uid%3D0%26rau%3D0&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text"><span class="citation book">Mire-Sluis, Anthony R.; Thorpe, Robin, ur. (1998). <a rel="nofollow" class="external text" href="http://www.sciencedirect.com/science/book/9780124983403"><i>Cytokines (Handbook of Immunopharmacology)</i></a>. Boston: Academic Press. <a href="/wiki/International_Standard_Book_Number" class="mw-redirect" title="International Standard Book Number">ISBN</a> <a href="/wiki/Posebno:Tra%C5%BEi_ISBN/0-12-498340-5" title="Posebno:Traži ISBN/0-12-498340-5">0-12-498340-5</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Cytokines+%28Handbook+of+Immunopharmacology%29&rft.date=1998&rft.place=Boston&rft.pub=Academic+Press&rft.isbn=0-12-498340-5&rft_id=http%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbook%2F9780124983403&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><a href="#cite_ref-6">↑</a></span> <span class="reference-text"><span class="citation web"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3576">„Entrez Gene: IL8 interleukin 8”</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.btitle=Entrez+Gene%3A+IL8+interleukin+8&rft.atitle=&rft_id=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3FDb%3Dgene%26Cmd%3DShowDetailView%26TermToSearch%3D3576&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid9702410-7"><span class="mw-cite-backlink"><a href="#cite_ref-pmid9702410_7-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Köhidai L, Csaba G (July 1998). „Chemotaxis and chemotactic selection induced with cytokines (IL-8, RANTES and TNF-alpha) in the unicellular Tetrahymena pyriformis”. <i>Cytokine</i> <b>10</b> (7): 481–6. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1006%2Fcyto.1997.0328">10.1006/cyto.1997.0328</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/9702410">9702410</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Chemotaxis+and+chemotactic+selection+induced+with+cytokines+%28IL-8%2C+RANTES+and+TNF-alpha%29+in+the+unicellular+Tetrahymena+pyriformis&rft.jtitle=Cytokine&rft.aulast=K%C3%B6hidai+L%2C+Csaba+G&rft.au=K%C3%B6hidai+L%2C+Csaba+G&rft.date=July+1998&rft.volume=10&rft.issue=7&rft.pages=481%E2%80%936&rft_id=info:doi/10.1006%2Fcyto.1997.0328&rft_id=info:pmid/9702410&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><a href="#cite_ref-8">↑</a></span> <span class="reference-text">Haake, SK, Huang, GTJ: Molecular Biology of the host-Microbe Interaction in Periodontal Diseases (Selected Topics). In Newman, Takei, Carranza, editors: <i>Clinical Periodontology</i>, 9th Edition. Philadelphia: W.B.Saunders Co. 2002. page 162.</span> </li> <li id="cite_note-Psoriasis-9"><span class="mw-cite-backlink"><a href="#cite_ref-Psoriasis_9-0">↑</a></span> <span class="reference-text"><span class="citation web"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20070823235422/http://www.ucsf.edu/dpsl/psoriasis.html">„Psoriasis”</a>. Arhivirano iz <a rel="nofollow" class="external text" href="http://www.ucsf.edu/dpsl/psoriasis.html">originala</a> na datum 2007-08-23<span class="reference-accessdate">. Pristupljeno 2014-05-23</span>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.btitle=Psoriasis&rft.atitle=&rft_id=https%3A%2F%2Fweb.archive.org%2Fweb%2F20070823235422%2Fhttp%3A%2F%2Fwww.ucsf.edu%2Fdpsl%2Fpsoriasis.html&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid10477716-10"><span class="mw-cite-backlink"><a href="#cite_ref-pmid10477716_10-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Vlahopoulos S, Boldogh I, Casola A, Brasier AR (September 1999). „Nuclear factor-kappaB-dependent induction of interleukin-8 gene expression by tumor necrosis factor alpha: evidence for an antioxidant sensitive activating pathway distinct from nuclear translocation”. <i>Blood</i> <b>94</b> (6): 1878–89. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/10477716">10477716</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Nuclear+factor-kappaB-dependent+induction+of+interleukin-8+gene+expression+by+tumor+necrosis+factor+alpha%3A+evidence+for+an+antioxidant+sensitive+activating+pathway+distinct+from+nuclear+translocation&rft.jtitle=Blood&rft.aulast=Vlahopoulos+S%2C+Boldogh+I%2C+Casola+A%2C+Brasier+AR&rft.au=Vlahopoulos+S%2C+Boldogh+I%2C+Casola+A%2C+Brasier+AR&rft.date=September+1999&rft.volume=94&rft.issue=6&rft.pages=1878%E2%80%9389&rft_id=info:pmid/10477716&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid15121655-11"><span class="mw-cite-backlink"><a href="#cite_ref-pmid15121655_11-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Brown AS, Hooton J, Schaefer CA, Zhang H, Petkova E, Babulas V, Perrin M, Gorman JM, Susser ES (May 2004). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_american-journal-of-psychiatry_2004-05_161_5/page/889">„Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring”</a>. <i>Am J Psychiatry</i> <b>161</b> (5): 889–95. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1176%2Fappi.ajp.161.5.889">10.1176/appi.ajp.161.5.889</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15121655">15121655</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Elevated+maternal+interleukin-8+levels+and+risk+of+schizophrenia+in+adult+offspring&rft.jtitle=Am+J+Psychiatry&rft.aulast=Brown+AS%2C+Hooton+J%2C+Schaefer+CA%2C+Zhang+H%2C+Petkova+E%2C+Babulas+V%2C+Perrin+M%2C+Gorman+JM%2C+Susser+ES&rft.au=Brown+AS%2C+Hooton+J%2C+Schaefer+CA%2C+Zhang+H%2C+Petkova+E%2C+Babulas+V%2C+Perrin+M%2C+Gorman+JM%2C+Susser+ES&rft.date=May+2004&rft.volume=161&rft.issue=5&rft.pages=889%E2%80%9395&rft_id=info:doi/10.1176%2Fappi.ajp.161.5.889&rft_id=info:pmid/15121655&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_american-journal-of-psychiatry_2004-05_161_5%2Fpage%2F889&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid15291683-12"><span class="mw-cite-backlink"><a href="#cite_ref-pmid15291683_12-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Zhang XY, Zhou DF, Cao LY, Zhang PY, Wu GY, Shen YC (July 2004). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20130527192623/http://www.jclinpsychiatry.com/abstracts/abstracts.asp?abstract=200407/070407.htm">„Changes in serum interleukin-2, -6, and -8 levels before and during treatment with risperidone and haloperidol: relationship to outcome in schizophrenia”</a>. <i>J Clin Psychiatry</i> <b>65</b> (7): 940–7. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15291683">15291683</a>. Arhivirano iz <a rel="nofollow" class="external text" href="http://www.jclinpsychiatry.com/abstracts/abstracts.asp?abstract=200407/070407.htm">originala</a> na datum 2013-05-27<span class="reference-accessdate">. Pristupljeno 2014-05-23</span>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Changes+in+serum+interleukin-2%2C+-6%2C+and+-8+levels+before+and+during+treatment+with+risperidone+and+haloperidol%3A+relationship+to+outcome+in+schizophrenia&rft.jtitle=J+Clin+Psychiatry&rft.aulast=Zhang+XY%2C+Zhou+DF%2C+Cao+LY%2C+Zhang+PY%2C+Wu+GY%2C+Shen+YC&rft.au=Zhang+XY%2C+Zhou+DF%2C+Cao+LY%2C+Zhang+PY%2C+Wu+GY%2C+Shen+YC&rft.date=July+2004&rft.volume=65&rft.issue=7&rft.pages=940%E2%80%937&rft_id=info:pmid/15291683&rft_id=https%3A%2F%2Fweb.archive.org%2Fweb%2F20130527192623%2Fhttp%3A%2F%2Fwww.jclinpsychiatry.com%2Fabstracts%2Fabstracts.asp%3Fabstract%3D200407%2F070407.htm&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-pmid12433287-13"><span class="mw-cite-backlink"><a href="#cite_ref-pmid12433287_13-0">↑</a></span> <span class="reference-text"><span class="citation Journal">Bacon K, Baggiolini M, Broxmeyer H, Horuk R, Lindley I, Mantovani A, Maysushima K, Murphy P, Nomiyama H, Oppenheim J, Rot A, Schall T, Tsang M, Thorpe R, Van Damme J, Wadhwa M, Yoshie O, Zlotnik A, Zoon K (October 2002). „Chemokine/chemokine receptor nomenclature”. <i>J. Interferon Cytokine Res.</i> <b>22</b> (10): 1067–8. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1089%2F107999002760624305">10.1089/107999002760624305</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/12433287">12433287</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Chemokine%2Fchemokine+receptor+nomenclature&rft.jtitle=J.+Interferon+Cytokine+Res.&rft.aulast=Bacon+K%2C+Baggiolini+M%2C+Broxmeyer+H%2C+Horuk+R%2C+Lindley+I%2C+Mantovani+A%2C+Maysushima+K%2C+Murphy+P%2C+Nomiyama+H%2C+Oppenheim+J%2C+Rot+A%2C+Schall+T%2C+Tsang+M%2C+Thorpe+R%2C+Van+Damme+J%2C+Wadhwa+M%2C+Yoshie+O%2C+Zlotnik+A%2C+Zoon+K&rft.au=Bacon+K%2C+Baggiolini+M%2C+Broxmeyer+H%2C+Horuk+R%2C+Lindley+I%2C+Mantovani+A%2C+Maysushima+K%2C+Murphy+P%2C+Nomiyama+H%2C+Oppenheim+J%2C+Rot+A%2C+Schall+T%2C+Tsang+M%2C+Thorpe+R%2C+Van+Damme+J%2C+Wadhwa+M%2C+Yoshie+O%2C+Zlotnik+A%2C+Zoon+K&rft.date=October+2002&rft.volume=22&rft.issue=10&rft.pages=1067%E2%80%938&rft_id=info:doi/10.1089%2F107999002760624305&rft_id=info:pmid/12433287&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Literatura">Literatura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interleukin_8&veaction=edit&section=7" title="Uredi odjeljak Literatura" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Interleukin_8&action=edit&section=7" title="Uredi kôd odjeljka Literatura"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r41379810">.mw-parser-output .refbegin{font-size:90%;margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}</style><div class="refbegin refbegin-columns references-column-count references-column-count-2" style="column-count: 2;"> <ul><li><span class="citation Journal">Baggiolini M, Clark-Lewis I (1992). „Interleukin-8, a chemotactic and inflammatory cytokine”. <i>FEBS Lett.</i> <b>307</b> (1): 97–101. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2F0014-5793%2892%2980909-Z">10.1016/0014-5793(92)80909-Z</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/1639201">1639201</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Interleukin-8%2C+a+chemotactic+and+inflammatory+cytokine&rft.jtitle=FEBS+Lett.&rft.aulast=Baggiolini+M%2C+Clark-Lewis+I&rft.au=Baggiolini+M%2C+Clark-Lewis+I&rft.date=1992&rft.volume=307&rft.issue=1&rft.pages=97%E2%80%93101&rft_id=info:doi/10.1016%2F0014-5793%2892%2980909-Z&rft_id=info:pmid/1639201&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></li> <li><span class="citation Journal">Wahl SM, Greenwell-Wild T, Hale-Donze H, <i>et al.</i> (2000). „Permissive factors for HIV-1 infection of macrophages”. <i>J. 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title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Modulation+of+HIV-1+transcription+by+cytokines+and+chemokines&rft.jtitle=Mini+reviews+in+medicinal+chemistry&rft.aulast=Copeland+KF&rft.au=Copeland+KF&rft.date=2006&rft.volume=5&rft.issue=12&rft.pages=1093%E2%80%93101&rft_id=info:doi/10.2174%2F138955705774933383&rft_id=info:pmid/16375755&rfr_id=info:sid/en.wikipedia.org:Interleukin_8"><span style="display: none;"> </span></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="Spoljašnje_veze"><span id="Spolja.C5.A1nje_veze"></span>Spoljašnje veze</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interleukin_8&veaction=edit&section=8" title="Uredi odjeljak Spoljašnje veze" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Interleukin_8&action=edit&section=8" title="Uredi kôd odjeljka Spoljašnje veze"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Medical_Subject_Headings" class="mw-redirect" title="Medical Subject Headings">MeSH</a> <i><a rel="nofollow" class="external text" href="//www.nlm.nih.gov/cgi/mesh/2009/MB_cgi?mode=&term=Interleukin-8">Interleukin-8</a></i></li></ul> <ul><li><span typeof="mw:File"><a href="https://commons.wikimedia.org/wiki/Cytokines" title="Cytokines"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/12px-Commons-logo.svg.png" decoding="async" width="12" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/18px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/24px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span> <a href="https://commons.wikimedia.org/wiki/Main_page" class="extiw" title="commons:Main page">Wikimedia Commons</a> ima još multimedijalnih datoteka vezanih za: <b><i><a href="https://commons.wikimedia.org/wiki/Category:Cytokines" class="extiw" title="commons:Category:Cytokines">Interleukin 8</a></i></b></li></ul> <div style="clear:both;"></div> <div class="navbox-styles nomobile"><style data-mw-deduplicate="TemplateStyles:r41348688">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output .navbox+.navbox-styles+.navbox{margin-top:-1px}.mw-parser-output .navbox-inner,.mw-parser-output .navbox-subgroup{width:100%}.mw-parser-output .navbox-group,.mw-parser-output .navbox-title,.mw-parser-output .navbox-abovebelow{padding:0.25em 1em;line-height:1.5em;text-align:center}.mw-parser-output .navbox-group{white-space:nowrap;text-align:right}.mw-parser-output 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class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><table style="background:transparent; border:1px solid #f0f0f0; margin-top:0.5em;"> <tbody><tr><td><table style="width:200px; float:left; border-collapse:collapse; margin:3px; background-color:#f8f8f8;"><tbody><tr><td style="height:200px; border:1px solid #CCCCCC; padding:0px;"><figure class="mw-halign-center mw-image-border" typeof="mw:File"><a href="/wiki/Datoteka:PDB_1icw_EBI.jpg" class="mw-file-description" title="1icw: Interleukin 8, mutant sa Glu 38 zamenjenim sa Cys i Cys 50 zamenjenim sa Ala"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_1icw_EBI.jpg/180px-PDB_1icw_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_1icw_EBI.jpg/270px-PDB_1icw_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4f/PDB_1icw_EBI.jpg/360px-PDB_1icw_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a><figcaption><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1icw">1icw</a></span></b>: Interleukin 8, mutant sa <a href="/wiki/Glu" class="mw-redirect" title="Glu">Glu</a> 38 zamenjenim sa <a href="/wiki/Cys" class="mw-redirect" title="Cys">Cys</a> i <a href="/wiki/Cys" class="mw-redirect" title="Cys">Cys</a> 50 zamenjenim sa <a href="/wiki/Ala" class="mw-redirect" title="Ala">Ala</a> </figcaption></figure></td></tr><tr style="border-right:1px solid #F0F0F0; border-bottom:1px solid #f0f0f0; border-left:1px solid #f0f0f0; vertical-align:top;"><td style="display:block; font-size:1em; height:6.2em; padding:0px;"><div class="gallerytext" style="height:6.1em; width:187px; line-height:1.3em; padding:2px 6px 1px 6px; overflow-y:auto; margin:0px; border:none; border-width:0px;"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1icw">1icw</a></span></b>: Interleukin 8, mutant sa <a href="/wiki/Glu" class="mw-redirect" title="Glu">Glu</a> 38 zamenjenim sa <a href="/wiki/Cys" class="mw-redirect" title="Cys">Cys</a> i <a href="/wiki/Cys" class="mw-redirect" title="Cys">Cys</a> 50 zamenjenim sa <a href="/wiki/Ala" class="mw-redirect" title="Ala">Ala</a>  </div></td></tr></tbody></table><table style="width:200px; float:left; border-collapse:collapse; margin:3px; background-color:#f8f8f8;"><tbody><tr><td style="height:200px; border:1px solid #CCCCCC; padding:0px;"><figure class="mw-halign-center mw-image-border" typeof="mw:File"><a href="/wiki/Datoteka:PDB_1ikl_EBI.jpg" class="mw-file-description" title="1ikl: NMR studija monomernog ljudskog interleukina 8 (minimizovana srednja struktura)"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/PDB_1ikl_EBI.jpg/180px-PDB_1ikl_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/PDB_1ikl_EBI.jpg/270px-PDB_1ikl_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/PDB_1ikl_EBI.jpg/360px-PDB_1ikl_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a><figcaption><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ikl">1ikl</a></span></b>: <a href="/wiki/NMR" class="mw-redirect" title="NMR">NMR</a> studija monomernog ljudskog interleukina 8 (minimizovana srednja struktura) </figcaption></figure></td></tr><tr style="border-right:1px solid #F0F0F0; border-bottom:1px solid #f0f0f0; border-left:1px solid #f0f0f0; vertical-align:top;"><td style="display:block; font-size:1em; height:6.2em; padding:0px;"><div class="gallerytext" style="height:6.1em; width:187px; line-height:1.3em; padding:2px 6px 1px 6px; overflow-y:auto; margin:0px; border:none; border-width:0px;"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ikl">1ikl</a></span></b>: <a href="/wiki/NMR" class="mw-redirect" title="NMR">NMR</a> studija monomernog ljudskog interleukina 8 (minimizovana srednja struktura)  </div></td></tr></tbody></table><table style="width:200px; float:left; border-collapse:collapse; margin:3px; background-color:#f8f8f8;"><tbody><tr><td style="height:200px; border:1px solid #CCCCCC; padding:0px;"><figure class="mw-halign-center mw-image-border" typeof="mw:File"><a href="/wiki/Datoteka:PDB_1ikm_EBI.jpg" class="mw-file-description" title="1ikm: NMR studija monomernog ljudskog interleukina 8 (30 struktura)"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/00/PDB_1ikm_EBI.jpg/180px-PDB_1ikm_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/00/PDB_1ikm_EBI.jpg/270px-PDB_1ikm_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/00/PDB_1ikm_EBI.jpg/360px-PDB_1ikm_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a><figcaption><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ikm">1ikm</a></span></b>: <a href="/wiki/NMR" class="mw-redirect" title="NMR">NMR</a> studija monomernog ljudskog interleukina 8 (30 struktura) </figcaption></figure></td></tr><tr style="border-right:1px solid #F0F0F0; border-bottom:1px solid #f0f0f0; border-left:1px solid #f0f0f0; vertical-align:top;"><td style="display:block; font-size:1em; height:6.2em; padding:0px;"><div class="gallerytext" style="height:6.1em; width:187px; line-height:1.3em; padding:2px 6px 1px 6px; overflow-y:auto; margin:0px; border:none; border-width:0px;"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ikm">1ikm</a></span></b>: <a href="/wiki/NMR" class="mw-redirect" title="NMR">NMR</a> studija monomernog ljudskog interleukina 8 (30 struktura)  </div></td></tr></tbody></table><table style="width:200px; float:left; border-collapse:collapse; margin:3px; background-color:#f8f8f8;"><tbody><tr><td style="height:200px; border:1px solid #CCCCCC; padding:0px;"><figure class="mw-halign-center mw-image-border" typeof="mw:File"><a href="/wiki/Datoteka:PDB_1il8_EBI.jpg" class="mw-file-description" title="1il8: Tri dimenzionalna struktura interleukina 8 u rastvoru"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/27/PDB_1il8_EBI.jpg/180px-PDB_1il8_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/27/PDB_1il8_EBI.jpg/270px-PDB_1il8_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/27/PDB_1il8_EBI.jpg/360px-PDB_1il8_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a><figcaption><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1il8">1il8</a></span></b>: Tri dimenzionalna struktura interleukina 8 u rastvoru </figcaption></figure></td></tr><tr style="border-right:1px solid #F0F0F0; border-bottom:1px solid #f0f0f0; border-left:1px solid #f0f0f0; vertical-align:top;"><td style="display:block; font-size:1em; height:6.2em; padding:0px;"><div class="gallerytext" style="height:6.1em; width:187px; line-height:1.3em; padding:2px 6px 1px 6px; overflow-y:auto; margin:0px; border:none; border-width:0px;"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1il8">1il8</a></span></b>: Tri dimenzionalna struktura interleukina 8 u rastvoru  </div></td></tr></tbody></table><table style="width:200px; float:left; border-collapse:collapse; margin:3px; background-color:#f8f8f8;"><tbody><tr><td style="height:200px; border:1px solid #CCCCCC; padding:0px;"><figure class="mw-halign-center mw-image-border" typeof="mw:File"><a href="/wiki/Datoteka:PDB_1ilp_EBI.jpg" class="mw-file-description" title="1ilp: CXCR-1 N-terminalni peptid vezan za interleukin 8"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2b/PDB_1ilp_EBI.jpg/180px-PDB_1ilp_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2b/PDB_1ilp_EBI.jpg/270px-PDB_1ilp_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2b/PDB_1ilp_EBI.jpg/360px-PDB_1ilp_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a><figcaption><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ilp">1ilp</a></span></b>: <a href="/w/index.php?title=CXCR-1&action=edit&redlink=1" class="new" title="CXCR-1 (stranica ne postoji)">CXCR-1</a> N-terminalni peptid vezan za interleukin 8 </figcaption></figure></td></tr><tr style="border-right:1px solid #F0F0F0; border-bottom:1px solid #f0f0f0; border-left:1px solid #f0f0f0; vertical-align:top;"><td style="display:block; font-size:1em; height:6.2em; padding:0px;"><div class="gallerytext" style="height:6.1em; width:187px; line-height:1.3em; padding:2px 6px 1px 6px; overflow-y:auto; margin:0px; border:none; border-width:0px;"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ilp">1ilp</a></span></b>: <a href="/w/index.php?title=CXCR-1&action=edit&redlink=1" class="new" title="CXCR-1 (stranica ne postoji)">CXCR-1</a> N-terminalni peptid vezan za interleukin 8  </div></td></tr></tbody></table><table style="width:200px; float:left; border-collapse:collapse; margin:3px; background-color:#f8f8f8;"><tbody><tr><td style="height:200px; border:1px solid #CCCCCC; padding:0px;"><figure class="mw-halign-center mw-image-border" typeof="mw:File"><a href="/wiki/Datoteka:PDB_1ilq_EBI.jpg" class="mw-file-description" title="1ilq: CXCR-1 N-terminalni peptid vezan za interleukin 8 (minimizovana sredina)"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b5/PDB_1ilq_EBI.jpg/180px-PDB_1ilq_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b5/PDB_1ilq_EBI.jpg/270px-PDB_1ilq_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b5/PDB_1ilq_EBI.jpg/360px-PDB_1ilq_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a><figcaption><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ilq">1ilq</a></span></b>: <a href="/w/index.php?title=CXCR-1&action=edit&redlink=1" class="new" title="CXCR-1 (stranica ne postoji)">CXCR-1</a> N-terminalni peptid vezan za interleukin 8 (minimizovana sredina) </figcaption></figure></td></tr><tr style="border-right:1px solid #F0F0F0; border-bottom:1px solid #f0f0f0; border-left:1px solid #f0f0f0; vertical-align:top;"><td style="display:block; font-size:1em; height:6.2em; padding:0px;"><div class="gallerytext" style="height:6.1em; width:187px; line-height:1.3em; padding:2px 6px 1px 6px; overflow-y:auto; margin:0px; border:none; border-width:0px;"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ilq">1ilq</a></span></b>: <a href="/w/index.php?title=CXCR-1&action=edit&redlink=1" class="new" title="CXCR-1 (stranica ne postoji)">CXCR-1</a> N-terminalni peptid vezan za interleukin 8 (minimizovana sredina)  </div></td></tr></tbody></table><table style="width:200px; float:left; border-collapse:collapse; margin:3px; background-color:#f8f8f8;"><tbody><tr><td style="height:200px; border:1px solid #CCCCCC; padding:0px;"><figure class="mw-halign-center mw-image-border" typeof="mw:File"><a href="/wiki/Datoteka:PDB_1qe6_EBI.jpg" class="mw-file-description" title="1qe6: Interleukin 8 sa dodatim disulfidom između ostataka 5 i 33 (L5C/H33C)"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/7a/PDB_1qe6_EBI.jpg/180px-PDB_1qe6_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/7a/PDB_1qe6_EBI.jpg/270px-PDB_1qe6_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/7a/PDB_1qe6_EBI.jpg/360px-PDB_1qe6_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a><figcaption><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1qe6">1qe6</a></span></b>: Interleukin 8 sa dodatim disulfidom između ostataka 5 i 33 (L5C/H33C) </figcaption></figure></td></tr><tr style="border-right:1px solid #F0F0F0; border-bottom:1px solid #f0f0f0; border-left:1px solid #f0f0f0; vertical-align:top;"><td style="display:block; font-size:1em; height:6.2em; padding:0px;"><div class="gallerytext" style="height:6.1em; width:187px; line-height:1.3em; padding:2px 6px 1px 6px; overflow-y:auto; margin:0px; border:none; border-width:0px;"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1qe6">1qe6</a></span></b>: Interleukin 8 sa dodatim disulfidom između ostataka 5 i 33 (L5C/H33C)  </div></td></tr></tbody></table><table style="width:200px; float:left; border-collapse:collapse; margin:3px; background-color:#f8f8f8;"><tbody><tr><td style="height:200px; border:1px solid #CCCCCC; padding:0px;"><figure class="mw-halign-center mw-image-border" typeof="mw:File"><a href="/wiki/Datoteka:PDB_2il8_EBI.jpg" class="mw-file-description" title="2il8: Tri dimenzionalna struktura interleukina 8 u rastvoru"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e9/PDB_2il8_EBI.jpg/180px-PDB_2il8_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e9/PDB_2il8_EBI.jpg/270px-PDB_2il8_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e9/PDB_2il8_EBI.jpg/360px-PDB_2il8_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a><figcaption><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2il8">2il8</a></span></b>: Tri dimenzionalna struktura interleukina 8 u rastvoru </figcaption></figure></td></tr><tr style="border-right:1px solid #F0F0F0; border-bottom:1px solid #f0f0f0; border-left:1px solid #f0f0f0; vertical-align:top;"><td style="display:block; font-size:1em; height:6.2em; padding:0px;"><div class="gallerytext" style="height:6.1em; width:187px; line-height:1.3em; padding:2px 6px 1px 6px; overflow-y:auto; margin:0px; border:none; border-width:0px;"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2il8">2il8</a></span></b>: Tri dimenzionalna struktura interleukina 8 u rastvoru  </div></td></tr></tbody></table><table style="width:200px; float:left; border-collapse:collapse; margin:3px; background-color:#f8f8f8;"><tbody><tr><td style="height:200px; border:1px solid #CCCCCC; padding:0px;"><figure class="mw-halign-center mw-image-border" typeof="mw:File"><a href="/wiki/Datoteka:PDB_3il8_EBI.jpg" class="mw-file-description" title="3il8: Kristalna struktura interleukina 8: simbioza NMR i kristalografije"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6d/PDB_3il8_EBI.jpg/180px-PDB_3il8_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/6d/PDB_3il8_EBI.jpg/270px-PDB_3il8_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/6d/PDB_3il8_EBI.jpg/360px-PDB_3il8_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a><figcaption><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3il8">3il8</a></span></b>: Kristalna struktura interleukina 8: simbioza <a href="/wiki/NMR" class="mw-redirect" title="NMR">NMR</a> i <a href="/wiki/Kristalografija" title="Kristalografija">kristalografije</a> </figcaption></figure></td></tr><tr style="border-right:1px solid #F0F0F0; border-bottom:1px solid #f0f0f0; border-left:1px solid #f0f0f0; vertical-align:top;"><td style="display:block; font-size:1em; height:6.2em; padding:0px;"><div class="gallerytext" style="height:6.1em; width:187px; line-height:1.3em; padding:2px 6px 1px 6px; overflow-y:auto; margin:0px; border:none; border-width:0px;"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3il8">3il8</a></span></b>: Kristalna struktura interleukina 8: simbioza <a href="/wiki/NMR" class="mw-redirect" title="NMR">NMR</a> i <a href="/wiki/Kristalografija" title="Kristalografija">kristalografije</a>  </div></td></tr></tbody></table></td></tr></tbody></table></div></td></tr></tbody></table></div> <div class="navbox-styles nomobile"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41348688"></div><div role="navigation" class="navbox" aria-labelledby="Interleukini" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41556979"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41556873"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-prikaži"><a href="/wiki/%C5%A0ablon:Interleukini-lat" title="Šablon:Interleukini-lat"><abbr title="Pogledajte šablon" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">p</abbr></a></li><li class="nv-razgovor"><a href="/w/index.php?title=Razgovor_o_%C5%A1ablonu:Interleukini-lat&action=edit&redlink=1" class="new" title="Razgovor o šablonu:Interleukini-lat (stranica ne postoji)"><abbr title="Razgovarajte o šablonu" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">r</abbr></a></li><li class="nv-uredi"><a class="external text" href="https://sh.wikipedia.org/w/index.php?title=%C5%A0ablon:Interleukini-lat&action=edit"><abbr title="Uredite šablon" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">u</abbr></a></li></ul></div><div id="Interleukini" style="font-size:114%;margin:0 4em"><a href="/wiki/Interleukini" class="mw-redirect" title="Interleukini">Interleukini</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_1" title="Interleukin 1">IL-1</a> •  <a href="/wiki/Interleukin_2" title="Interleukin 2">IL-2</a> •  <a href="/wiki/Interleukin_3" title="Interleukin 3">IL-3</a> •  <a href="/wiki/Interleukin_4" title="Interleukin 4">IL-4</a> •  <a href="/wiki/Interleukin_5" title="Interleukin 5">IL-5</a> •  <a href="/wiki/Interleukin_6" title="Interleukin 6">IL-6</a> •  <a href="/wiki/Interleukin_7" title="Interleukin 7">IL-7</a> •  <a class="mw-selflink selflink">IL-8</a> •  <a href="/wiki/Interleukin_9" title="Interleukin 9">IL-9</a> •  <a href="/wiki/Interleukin_10" title="Interleukin 10">IL-10</a> •  <a href="/wiki/Interleukin_11" title="Interleukin 11">IL-11</a> •  <a href="/wiki/Interleukin_12" title="Interleukin 12">IL-12</a> (<a href="/wiki/Interleukin_12B" title="Interleukin 12B">B</a>) •  <a href="/wiki/Interleukin_13" title="Interleukin 13">IL-13</a> •  <a href="/wiki/Interleukin_14" title="Interleukin 14">IL-14</a> •  <a href="/wiki/Interleukin_15" title="Interleukin 15">IL-15</a> •  <a href="/wiki/Interleukin_16" title="Interleukin 16">IL-16</a> •  <a href="/wiki/Interleukin_17" title="Interleukin 17">IL-17</a> (<a href="/wiki/Interleukin_17A" title="Interleukin 17A">A</a>) •  <a href="/wiki/Interleukin_18" title="Interleukin 18">IL-18</a> •  <a href="/wiki/Interleukin_19" title="Interleukin 19">IL-19</a> •  <a href="/wiki/Interleukin_20" title="Interleukin 20">IL-20</a> •  <a href="/wiki/Interleukin_21" title="Interleukin 21">IL-21</a> •  <a href="/wiki/Interleukin_22" title="Interleukin 22">IL-22</a> •  <a href="/wiki/Interleukin_23" title="Interleukin 23">IL-23</a> •  <a href="/wiki/Interleukin_24" title="Interleukin 24">IL-24</a> •  <a href="/wiki/Interleukin_25" title="Interleukin 25">IL-25</a> •  <a href="/wiki/Interleukin_26" title="Interleukin 26">IL-26</a> •  <a href="/wiki/Interleukin_27" title="Interleukin 27">IL-27</a> •  <a href="/wiki/Interleukin_28" title="Interleukin 28">IL-28</a> •  <a href="/wiki/Interleukin_29" title="Interleukin 29">IL-29</a> •  <a href="/wiki/Interleukin_30" title="Interleukin 30">IL-30</a> •  <a href="/wiki/Interleukin_31" title="Interleukin 31">IL-31</a> •  <a href="/wiki/Interleukin_32" title="Interleukin 32">IL-32</a> •  <a href="/wiki/Interleukin_33" title="Interleukin 33">IL-33</a> •  <a href="/wiki/Interleukin_34" title="Interleukin 34">IL-34</a> •  <a href="/wiki/Interleukin_35" title="Interleukin 35">IL-35</a></div></td></tr></tbody></table></div> <div class="navbox-styles nomobile"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41348688"></div><div role="navigation" class="navbox" aria-labelledby="Ćelijska_komunikacija:_Citokini" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41556979"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r41556873"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-prikaži"><a href="/wiki/%C5%A0ablon:Citokini-lat" title="Šablon:Citokini-lat"><abbr title="Pogledajte šablon" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">p</abbr></a></li><li class="nv-razgovor"><a href="/wiki/Razgovor_o_%C5%A1ablonu:Citokini-lat" title="Razgovor o šablonu:Citokini-lat"><abbr title="Razgovarajte o šablonu" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">r</abbr></a></li><li class="nv-uredi"><a class="external text" href="https://sh.wikipedia.org/w/index.php?title=%C5%A0ablon:Citokini-lat&action=edit"><abbr title="Uredite šablon" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">u</abbr></a></li></ul></div><div id="Ćelijska_komunikacija:_Citokini" style="font-size:114%;margin:0 4em"><a href="/wiki/%C4%86elijska_komunikacija" title="Ćelijska komunikacija">Ćelijska komunikacija</a>: <a href="/wiki/Citokini" class="mw-redirect" title="Citokini">Citokini</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Po familiji</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interleukin" title="Interleukin">Interleukin</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/IL-1" class="mw-disambig" title="IL-1">IL-1</a> superfamilija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_1" title="Interleukin 1">1</a> (<a href="/wiki/Antagonist_interleukin-1_receptora" title="Antagonist interleukin-1 receptora">1Ra</a>) •  <a href="/wiki/Interleukin_18" title="Interleukin 18">18</a> •  <a href="/wiki/Interleukin_33" title="Interleukin 33">33</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">poput <a href="/wiki/IL-6" class="mw-disambig" title="IL-6">IL-6</a>/<a href="/wiki/Glikoprotein_130" title="Glikoprotein 130">gp130</a> koristeći</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_6" title="Interleukin 6">6</a>  •  <a href="/wiki/Interleukin_11" title="Interleukin 11">11</a> •  <a href="/wiki/Interleukin_27" title="Interleukin 27">27</a> •  <a href="/wiki/Interleukin_30" title="Interleukin 30">30</a> •  <a href="/wiki/Interleukin_31" title="Interleukin 31">31</a> (+ne IL <a href="/wiki/Onkostatin_M" title="Onkostatin M">Onkostatin M</a>, <a href="/wiki/Inhibitorni_faktor_leukemije" title="Inhibitorni faktor leukemije">Inhibitorni faktor leukemije</a>, <a href="/wiki/Cilijarni_neurotrofni_faktor" title="Cilijarni neurotrofni faktor">Cilijarni neurotrofni faktor</a>, <a href="/wiki/Kardiotrofin_1" title="Kardiotrofin 1">Kardiotrofin 1</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/IL-10" class="mw-disambig" title="IL-10">IL-10</a> familija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_10" title="Interleukin 10">10</a> •  <a href="/wiki/Interleukin_19" title="Interleukin 19">19</a> •  <a href="/wiki/Interleukin_20" title="Interleukin 20">20</a> •  <a href="/wiki/Interleukin_22" title="Interleukin 22">22</a> •  <a href="/wiki/Interleukin_24" title="Interleukin 24">24</a> •  <a href="/wiki/Interleukin_26" title="Interleukin 26">26</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_III" title="Interferon tip III">Interferon tip III</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_28" title="Interleukin 28">28</a> •  <a href="/wiki/Interleukin_29" title="Interleukin 29">29</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Zajedni%C4%8Dki_gama_lanac" class="mw-redirect" title="Zajednički gama lanac">Zajednički γ-lanac</a> familija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_2" title="Interleukin 2">2</a>/<a href="/wiki/Interleukin_15" title="Interleukin 15">15</a> •  <a href="/wiki/Interleukin_3" title="Interleukin 3">3</a> •  <a href="/wiki/Interleukin_4" title="Interleukin 4">4</a> •  <a href="/wiki/Interleukin_7" title="Interleukin 7">7</a> •  <a href="/wiki/Interleukin_9" title="Interleukin 9">9</a> •  <a href="/wiki/Interleukin_13" title="Interleukin 13">13</a> •  <a href="/wiki/Interleukin_21" title="Interleukin 21">21</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/IL-12" class="mw-disambig" title="IL-12">IL-12</a> familija</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_12" title="Interleukin 12">12</a> (<a href="/wiki/Interleukin_12B" title="Interleukin 12B">B</a>) •  <a href="/wiki/Interleukin_23" title="Interleukin 23">23</a> •  <a href="/wiki/Interleukin_27" title="Interleukin 27">27</a> •  <a href="/wiki/Interleukin_35" title="Interleukin 35">35</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">Drugi</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_5" title="Interleukin 5">5</a> •  <a class="mw-selflink selflink">8</a> •  <a href="/wiki/Interleukin_14" title="Interleukin 14">14</a> •  <a href="/wiki/Interleukin_16" title="Interleukin 16">16</a> •  <a href="/wiki/Interleukin_17" title="Interleukin 17">17</a>/<a href="/wiki/Interleukin_25" title="Interleukin 25">25</a> (<a href="/wiki/Interleukin_17A" title="Interleukin 17A">A</a>) •  <a href="/wiki/Interleukin_32" title="Interleukin 32">32</a>  •  <a href="/wiki/Interleukin_34" title="Interleukin 34">34</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Hemokini" class="mw-redirect" title="Hemokini">Hemokini</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">CCL</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CCL1" title="CCL1">1</a> •  <a href="/wiki/CCL2" title="CCL2">2</a> •  <a href="/wiki/Makrofagni_inflamatorni_protein" title="Makrofagni inflamatorni protein">3</a> •  <a href="/wiki/CCL4" title="CCL4">4</a> •  <a href="/wiki/CCL5" title="CCL5">5</a> •  <a href="/wiki/CCL6" title="CCL6">6</a> •  <a href="/wiki/CCL7" title="CCL7">7</a> •  <a href="/wiki/CCL8" title="CCL8">8</a> •  <a href="/wiki/CCL9" title="CCL9">9</a> •  <a href="/wiki/CCL9" title="CCL9">10</a> •  <a href="/wiki/CCL11" title="CCL11">11</a> •  <a href="/wiki/CCL12" title="CCL12">12</a> •  <a href="/wiki/CCL13" title="CCL13">13</a> •  <a href="/wiki/CCL14" title="CCL14">14</a> •  <a href="/wiki/CCL15" title="CCL15">15</a> •  <a href="/wiki/CCL16" title="CCL16">16</a> •  <a href="/wiki/CCL17" title="CCL17">17</a> •  <a href="/wiki/CCL18" title="CCL18">18</a> •  <a href="/wiki/CCL19" title="CCL19">19</a> •  <a href="/wiki/CCL20" title="CCL20">20</a> •  <a href="/wiki/CCL21" title="CCL21">21</a> •  <a href="/wiki/CCL22" title="CCL22">22</a> •  <a href="/wiki/CCL23" title="CCL23">23</a> •  <a href="/wiki/CCL24" title="CCL24">24</a> •  <a href="/wiki/CCL25" title="CCL25">25</a> •  <a href="/wiki/CCL26" title="CCL26">26</a> •  <a href="/wiki/CCL27" title="CCL27">27</a> •  <a href="/wiki/CCL28" title="CCL28">28</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">CXCL</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CXCL1" title="CXCL1">1</a> •  <a href="/wiki/CXCL2" title="CXCL2">2</a> •  <a href="/wiki/CXCL3" title="CXCL3">3</a> •  <a href="/wiki/Trombocit_faktor_4" title="Trombocit faktor 4">4</a> •  <a href="/wiki/CXCL5" title="CXCL5">5</a> •  <a href="/wiki/CXCL6" title="CXCL6">6</a> •  <a href="/wiki/CXCL7" title="CXCL7">7</a> •  <a class="mw-selflink selflink">8</a> •  <a href="/wiki/CXCL9" title="CXCL9">9</a> •  <a href="/wiki/CXCL10" title="CXCL10">10</a> •  <a href="/wiki/CXCL11" title="CXCL11">11</a> •  <a href="/wiki/CXCL12" title="CXCL12">12</a> •  <a href="/wiki/CXCL13" title="CXCL13">13</a> •  <a href="/wiki/CXCL14" title="CXCL14">14</a> •  <a href="/wiki/CXCL15" title="CXCL15">15</a> •  <a href="/wiki/CXCL16" title="CXCL16">16</a> •  <a href="/wiki/CXCL17" title="CXCL17">17</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">CX3CL</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CX3CL1" title="CX3CL1">1</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">XCL</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/XCL1" title="XCL1">1</a> •  <a href="/wiki/XCL2" title="XCL2">2</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Faktori_nekroze_tumora" title="Faktori nekroze tumora">TNF</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">Glavni</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">TNF-alfa</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;">TNF (<a href="/wiki/Ligand_(biohemija)" title="Ligand (biohemija)">ligand</a>) superfamilija</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/4-1BB_ligand" title="4-1BB ligand">4-1BB ligand</a> •  <a href="/wiki/Faktor_aktivacije_B-%C4%87elija" title="Faktor aktivacije B-ćelija">Faktor aktivacije B-ćelija</a> •  <a href="/wiki/Fas_ligand" title="Fas ligand">FAS ligand</a> •  <a href="/wiki/Limfotoksin" title="Limfotoksin">Limfotoksin</a> •  <a href="/wiki/OX40L" title="OX40L">OX40L</a> •  <a href="/wiki/RANKL" title="RANKL">RANKL</a> •  <a href="/wiki/TRAIL" title="TRAIL">TRAIL</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Klaster_diferencijacije" title="Klaster diferencijacije">Klaster diferencijacije</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CD70" title="CD70">CD70</a> •  <a href="/wiki/CD153" title="CD153">CD153</a> •  <a href="/wiki/CD154" title="CD154">CD154</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon" title="Interferon">Interferon</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_I" title="Interferon tip I">I</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em">alfa ( <a href="/wiki/Pegilirani_interferon_alfa-2a" title="Pegilirani interferon alfa-2a">Pegilirani 2a</a>, <a href="/wiki/Pegilirani_interferon_alfa-2b" title="Pegilirani interferon alfa-2b">Pegilirani 2b</a>), beta (<a href="/wiki/Interferon_beta-1a" title="Interferon beta-1a">1a</a>, <a href="/wiki/Interferon_beta-1b" title="Interferon beta-1b">1b</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_II" title="Interferon tip II">II</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interferon-gama" title="Interferon-gama">Gama</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;background-color: AntiqueWhite"><div style="padding:0em 0.75em;"><a href="/wiki/Interferon_tip_III" title="Interferon tip III">III</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interleukin_28" title="Interleukin 28">IL-28</a> •  <a href="/wiki/Interleukin_29" title="Interleukin 29">IL-29</a></div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Drugi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Monokin" title="Monokin">Monokin</a> •  <a href="/wiki/Limfokin" title="Limfokin">Limfokin</a> (<a href="/wiki/Limfotoksin" title="Limfotoksin">Limfotoksin</a>, <a href="/wiki/Faktor_transfera" title="Faktor transfera">Faktor transfera</a>) •  <a href="/wiki/Faktor_rasta" title="Faktor rasta">Faktor rasta</a> •  <a href="/wiki/Hematopoeza" title="Hematopoeza">Hematopoeza</a> (<a href="/wiki/Faktor_stem_%C4%87elija" title="Faktor stem ćelija">Faktor stem ćelija</a>, <a href="/wiki/Faktor_stimulacije_kolonije" title="Faktor stimulacije kolonije">Faktor stimulacije kolonije</a>) •  <a href="/wiki/GPI_(gen)" title="GPI (gen)">Faktor autokrinog motiliteta</a> •  <a href="/wiki/Osteopontin" title="Osteopontin">Osteopontin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Po funkciji</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><i><a href="/wiki/Proinflamatorni_citokin" title="Proinflamatorni citokin">proinflamatorni citokin</a></i> (<a href="/wiki/Interleukin_1" title="Interleukin 1">IL-1</a>, <a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">TNF-alfa</a>) •  <a href="/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije"><i>T<sub>h</sub>1</i></a> (<a href="/wiki/Interferon-gama" title="Interferon-gama">INF-gama</a> i <a href="/wiki/Faktor_nekroze_tumora-beta" class="mw-redirect" title="Faktor nekroze tumora-beta">TNF-beta</a>) •  <a href="/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije"><i>T<sub>h</sub>2</i></a> (<a href="/wiki/Interleukin_4" title="Interleukin 4">IL-4</a>, <a href="/wiki/Interleukin_5" title="Interleukin 5">IL-5</a>, <a href="/wiki/Interleukin_6" title="Interleukin 6">IL-6</a>, <a href="/wiki/Interleukin_10" title="Interleukin 10">IL-10</a>, <a href="/wiki/Interleukin_13" title="Interleukin 13">IL-13</a>) •  <a href="/wiki/T_pomo%C4%87ne_17_%C4%87elije" title="T pomoćne 17 ćelije"><i>T<sub>h</sub>17</i></a> (<a href="/wiki/Interleukin_17" title="Interleukin 17">IL-17</a>,<a href="/wiki/Interleukin_22" title="Interleukin 22">IL-22</a>)</div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite"><div><i><a href="/wiki/%C5%A0ablon:Biohemija_metanavs-lat" title="Šablon:Biohemija metanavs-lat">B</a> <a href="/wiki/%C5%A0ablon:Prenos_signala-lat" title="Šablon:Prenos signala-lat">trdu</a>: <a href="/w/index.php?title=%C5%A0ablon:Intercelularni_signalni_peptidi_i_proteini-lat&action=edit&redlink=1" class="new" title="Šablon:Intercelularni signalni peptidi i proteini-lat (stranica ne postoji)">peptidi</a> (<a href="/wiki/%C5%A0ablon:Neuropeptidi-lat" title="Šablon:Neuropeptidi-lat">nrpl</a>/<a href="/wiki/%C5%A0ablon:Faktori_rasta-lat" title="Šablon:Faktori rasta-lat">grfl</a>/<a href="/wiki/%C5%A0ablon:Citokini-lat" title="Šablon:Citokini-lat">cytl</a>/<a href="/wiki/%C5%A0ablon:Hormoni-lat" title="Šablon:Hormoni-lat">horl</a>), <a href="/w/index.php?title=%C5%A0ablon:Receptori_%C4%87elijske_povr%C5%A1ine-lat&action=edit&redlink=1" class="new" title="Šablon:Receptori ćelijske površine-lat (stranica ne postoji)">receptori</a> (<a href="/w/index.php?title=%C5%A0ablon:Ligand-kontrolisani_jonski_kanali-lat&action=edit&redlink=1" class="new" title="Šablon:Ligand-kontrolisani jonski kanali-lat (stranica ne postoji)">lgic</a>, <a href="/w/index.php?title=%C5%A0ablon:Enzim-vezani_receptori-lat&action=edit&redlink=1" class="new" title="Šablon:Enzim-vezani receptori-lat (stranica ne postoji)">enzr</a>, <a href="/wiki/%C5%A0ablon:G_protein_spregnuti_receptori-lat" title="Šablon:G protein spregnuti receptori-lat">gprc</a>, <a href="/wiki/%C5%A0ablon:Imunoglobulinska_superfamilija_imunskih_receptora-lat" title="Šablon:Imunoglobulinska superfamilija imunskih receptora-lat">igsr</a>, <a href="/w/index.php?title=%C5%A0ablon:Integrini-lat&action=edit&redlink=1" class="new" title="Šablon:Integrini-lat (stranica ne postoji)">intg</a>, <a href="/wiki/%C5%A0ablon:Neuropeptidni_receptori-lat" title="Šablon:Neuropeptidni receptori-lat">nrpr</a>/<a href="/wiki/%C5%A0ablon:Receptori_faktora_rasta-lat" title="Šablon:Receptori faktora rasta-lat">grfr</a>/<a href="/wiki/%C5%A0ablon:Citokinski_receptori-lat" class="mw-redirect" title="Šablon:Citokinski receptori-lat">cytr</a>), <a href="/w/index.php?title=%C5%A0ablon:Intracelularni_signalni_peptidi_i_proteini-lat&action=edit&redlink=1" class="new" title="Šablon:Intracelularni signalni peptidi i proteini-lat (stranica ne postoji)">itra</a> (<a href="/w/index.php?title=%C5%A0ablon:Adapterski_proteini-lat&action=edit&redlink=1" class="new" title="Šablon:Adapterski proteini-lat (stranica ne postoji)">adap</a>, <a href="/wiki/%C5%A0ablon:Regulatori_GTP-vezuju%C4%87ih_proteina-lat" title="Šablon:Regulatori GTP-vezujućih proteina-lat">gbpr</a>, <a href="/w/index.php?title=%C5%A0ablon:Aktivacija_MAP_kinaze-lat&action=edit&redlink=1" class="new" title="Šablon:Aktivacija MAP kinaze-lat (stranica ne postoji)">mapk</a>), <a href="/w/index.php?title=%C5%A0ablon:Kalcjiumska_signalizacija-lat&action=edit&redlink=1" class="new" title="Šablon:Kalcjiumska signalizacija-lat (stranica ne postoji)">calc</a>, <a href="/wiki/%C5%A0ablon:Lipidna_signalizacija-lat" title="Šablon:Lipidna signalizacija-lat">lipd</a>, signalni putevi (<a href="/w/index.php?title=%C5%A0ablon:Hedgehog_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Hedgehog signalni put-lat (stranica ne postoji)">hedp</a>, <a href="/w/index.php?title=%C5%A0ablon:Wnt_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Wnt signalni put-lat (stranica ne postoji)">wntp</a>, <a href="/w/index.php?title=%C5%A0ablon:TGF_beta_signalizacija-lat&action=edit&redlink=1" class="new" title="Šablon:TGF beta signalizacija-lat (stranica ne postoji)">tgfp</a>+<a href="/wiki/%C5%A0ablon:MAPK_ERK_signalni_put-lat" title="Šablon:MAPK ERK signalni put-lat">mapp</a>, <a href="/w/index.php?title=%C5%A0ablon:Notch_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Notch signalni put-lat (stranica ne postoji)">notp</a>, <a href="/w/index.php?title=%C5%A0ablon:JAK-STAT_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:JAK-STAT signalni put-lat (stranica ne postoji)">jakp</a>, <a href="/wiki/%C5%A0ablon:Apoptozni_signalni_put-lat" title="Šablon:Apoptozni signalni put-lat">fsap</a>, <a href="/w/index.php?title=%C5%A0ablon:Hippo_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:Hippo signalni put-lat (stranica ne postoji)">hipp</a>, <a href="/w/index.php?title=%C5%A0ablon:TLR_signalni_put-lat&action=edit&redlink=1" class="new" title="Šablon:TLR signalni put-lat (stranica ne postoji)">tlrp</a>)</i></div></td></tr></tbody></table></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="" lang="sh-Latn" dir="ltr">Izvor: <a dir="ltr" href="https://sh.wikipedia.org/w/index.php?title=Interleukin_8&oldid=42171011">https://sh.wikipedia.org/w/index.php?title=Interleukin_8&oldid=42171011</a></div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Posebno:Kategorije" title="Posebno:Kategorije">Kategorije</a>: <ul><li><a href="/wiki/Kategorija:Ljudski_proteini" title="Kategorija:Ljudski proteini">Ljudski proteini</a></li><li><a href="/wiki/Kategorija:Interleukini" title="Kategorija:Interleukini">Interleukini</a></li><li><a href="/wiki/Kategorija:Imunologija" 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