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NHR families | IUPHAR/BPS Guide to PHARMACOLOGY

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CONTENT START ==================== --> <div class="grid_12"> <!-- ==================== GRID 16 START ==================== --> <!-- --> <!-- ==================== GRID 16 START ==================== --> <div class="grid_16 alpha"> <a name="top"></a> <h4>Nuclear hormone receptors</h4> <div class="contentboxfullhelp"> <div class="textright"> <p> View a list of <a href="NHRListForward">nuclear hormone receptors</a> </p> <div style="text-align:right;"> <button class="button_gtoimmupdb_off" onClick='window.location.href="http://www.guidetoimmunopharmacology.org/GRAC/ReceptorFamiliesForward?type=NHR&CGTP=false"; return false;'>GtoImmuPdb View OFF</button> <button onClick="expandTree('family_tree');return false;">Expand all nodes</button> <button onClick="collapseTree('family_tree'); return false;">Collapse all nodes</button> </div> <ul class="mktree" id ="family_tree"><li class="liOpen" ID="node695"><span class="tree_root_node">Nuclear hormone receptors</span><span class="cgtp"> C</span> <a href="FamilyDisplayForward?familyId=695&familyType=NHR"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li class="liOpen" ID="node84"><a id="link84" href="FamilyDisplayForward?familyId=84">1A. Thyroid hormone receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node85"><a id="link85" href="FamilyDisplayForward?familyId=85">1B. Retinoic acid receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node86"><a id="link86" href="FamilyDisplayForward?familyId=86">1C. Peroxisome proliferator-activated receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node87"><a id="link87" href="FamilyDisplayForward?familyId=87">1D. Rev-Erb receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node88"><a id="link88" href="FamilyDisplayForward?familyId=88">1F. Retinoic acid-related orphans</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node89"><a id="link89" href="FamilyDisplayForward?familyId=89">1H. Liver X receptor-like receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node90"><a id="link90" href="FamilyDisplayForward?familyId=90">1I. Vitamin D receptor-like receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node91"><a id="link91" href="FamilyDisplayForward?familyId=91">2A. Hepatocyte nuclear factor-4 receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node92"><a id="link92" href="FamilyDisplayForward?familyId=92">2B. Retinoid X receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node93"><a id="link93" href="FamilyDisplayForward?familyId=93">2C. Testicular receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node94"><a id="link94" href="FamilyDisplayForward?familyId=94">2E. Tailless-like receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node95"><a id="link95" href="FamilyDisplayForward?familyId=95">2F. COUP-TF-like receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node97"><a id="link97" href="FamilyDisplayForward?familyId=97">3B. Estrogen-related receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node99"><a id="link99" href="FamilyDisplayForward?familyId=99">4A. Nerve growth factor IB-like receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node100"><a id="link100" href="FamilyDisplayForward?familyId=100">5A. Fushi tarazu F1-like receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node101"><a id="link101" href="FamilyDisplayForward?familyId=101">6A. Germ cell nuclear factor receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node102"><a id="link102" href="FamilyDisplayForward?familyId=102">0B. DAX-like receptors</a><span class="cgtp"> C</span></li><li class="liOpen" ID="node107">Steroid hormone receptors<span class="cgtp"> C</span> <a href="FamilyDisplayForward?familyId=107&familyType=NHR"><img style="vertical-align:top;" src="images/overview.png"/></a><ul style="margin-bottom:0px;"><li ID="node96"><a id="link96" href="FamilyDisplayForward?familyId=96">3A. Estrogen receptors</a><span class="cgtp"> C</span></li><li ID="node98"><a id="link98" href="FamilyDisplayForward?familyId=98">3C. 3-Ketosteroid receptors</a><span class="cgtp"> C</span></li></ul></li></ul></li></ul> <p style="font-size:95%;margin-top:30px;"> <span style="font-style:italic;">For information on the nomenclature of these receptors please see reference:</span><br/> Nuclear Receptors Nomenclature Committee (1999). A unified nomenclature system for the nuclear receptor superfamily. <i>Cell</i> <b>97</b>, 161-163. [PMID:<a href='javascript:newWindow("http://www.ncbi.nlm.nih.gov/pubmed/10219237?dopt=AbstractPlus")'>10219237</a>] </p> <p style="font-size:90%;text-align:center;margin-top:30px;"> <img src="images/NHR_graphic.png" alt="image of a NHR complex bound to DNA" width="526px" height="412px" /> <br/>Image generated from the 3D structure PDB entry <a href='javascript:newWindow("http://www.pdb.org/pdb/explore/explore.do?structureId=3E00")'>3E00</a>. </p> </div> </div> </div> <!-- ==================== GRID 16 END ========================================--> </div> <!-- ==================== CONTENT END ============================================ --> <!-- ====== Script to make help pop-up work ====== --> <script> // Popup Window var scrollTop = ''; var newHeight = '100'; /* $(window).bind('scroll', function() { scrollTop = $( window ).scrollTop(); newHeight = scrollTop + 100; }); */ $('.popup-trigger').click(function(e) { e.stopPropagation(); if(jQuery(window).width() < 767) { $(this).after( $(this).nextAll('.popup:first') ); 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