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Target search tools | IUPHAR/BPS Guide to PHARMACOLOGY

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============================================================ --> <div class="container_16"> <!-- ==================== BREADCRUMBS START - NEEDS TO BE UPDATED MANUALLY ==================== --> <div class="breadcrumbscont"> <ul class="crumbtext"> <li><a href="/index.jsp">Home</a></li> <li>Target search</li> </ul> </div> <!-- ==================== BREADCRUMBS END ======================================== --> <!-- ==================== CONTENT START ==================== --> <div class="grid_12"> <!-- ==================== GRID 16 START ==================== --> <div class="grid_16 alpha"> <a name="top"></a> <h4>Receptor and other target search tools</h4> <div class="contentboxfullhelp"> <div class="textright"> <p style="text-align: right;font-size:105%;margin:10px;font-weight:bold;"><a href="chemSearch.jsp">Ligand search tools and chemical structure editor</a> <a href="chemSearch.jsp"><img src="images_dev27082012/go.jpg"></a>&nbsp;&nbsp;<a href="pharmacologySearch.jsp">Pharmacology search tool</a> <a href="pharmacologySearch.jsp"><img src="images_dev27082012/go.jpg"></a></p> <form method="get" action="DatabaseSearchForward"> <fieldset> <h3>Target text search</h3> <a style="color:white;" href="JavaScript:callRef('helpPagePopup.jsp#recTextSearch', 800, 400)" title="Click here for help"><img class="logo" style="vertical-align:baseline;" src="images/help_blue_small.png" alt="Click here for help"/></a> <table cellpadding="10"> <tr> <td colspan="2"> Enter text to search: <input type="text" id="target_text" size="52" maxlength="300" name="searchString"/> <script> // $("#target_text").autocomplete({delay: 300, minLength: 2, source: "autocompleteTargets.jsp"}); // $("#target_text").autocomplete({delay: 300, minLength: 2, source: "autocompleteTargets.jsp", $("#target_text").catcomplete({delay: 300, minLength: 2, source: "autocompleteTargets.jsp", focus: function( event, ui ) { // do nothing on mouse over return false; }, select: function( event, ui ) { self.location.href = ui.item.value; return false; } }); </script> </td> </tr> <tr cellpadding="20"> <td align="left" valign="top"> Select fields to search:<br/><br/> <select name="searchCategories" multiple="true"> <option value="allRec" selected="selected">All</option> <optgroup label="Targets"> <option value="receptorName">Name</option> <option value="overview">Concise family overview</option> <option value="intro">Detailed family introduction</option> <option value="receptorComment">Comments</option> </optgroup> <optgroup label="Interactions"> <option value="interactionComment">Comments</option> </optgroup> <optgroup label="Immunopharmacology"> <option value="immComment">Immunopharmacology Comments</option> </optgroup> <optgroup label="Immuno Processes"> <option value="immProcess">Process Category</option> <option value="immProcessComment">Process Association Comments</option> <option value="immGoTerm">Gene Ontology (GO) Term</option> <option value="immGoID">Gene Ontology (GO) ID</option> </optgroup> <optgroup label="Immuno Celltypes"> <option value="immCelltype">Celltype Category</option> <option value="immCelltypeComment">Celltype Association Comments</option> <option value="immCoTerm">Cell Ontology (CO) Term</option> <option value="immCoId">Cell Ontology (CO) ID</option> <option value="immCoDef">Cell Ontology (CO) Term Definition</option> </optgroup> <optgroup label="Immuno Disease"> <option value="immDisease">Disease</option> <option value="immDiseaseComment">Disease Association Comment</option> </optgroup> <optgroup label="Associated protein"> <option value="assocProt">Name</option> <option value="assocProtComment">Comments</option> </optgroup> <optgroup label="Physiological function"> <option value="physFunDesc">Description</option> <option value="physFunTissue">Tissue</option> <option value="physFunComment">Comments</option> </optgroup> <optgroup label="Tissue distribution"> <option value="distribTissue">Tissue</option> <option value="distribTech">Technique</option> <option value="distribComment">Comments</option> </optgroup> <optgroup label="Functional assay"> <option value="fAssayDesc">Description</option> <option value="fAssayTissue">Tissue</option> <option value="fAssayResponse">Response</option> <option value="fAssayComment">Comments</option> </optgroup> <optgroup label="Consequences of altering gene expression"> <option value="altExpDesc">Description</option> <option value="altExpTissue">Tissue</option> <option value="altExpTech">Technique</option> <option value="altExpComment">Comments</option> </optgroup> <optgroup label="Biological Variants"> <option value="varEffect">Description/effect</option> <option value="varComment">Comments</option> </optgroup> <optgroup label="Mutations/pathophysiology"> <option value="pathoDisease">Disease</option> <option value="pathoRole">Role</option> <option value="pathoDrugs">Drugs</option> <option value="pathoSE">Side effect</option> <option value="pathoUse">Use</option> <option value="pathoComment">Comments</option> </optgroup> <optgroup label="Gene expression and pathophysiology"> <option value="expChange">Description</option> <option value="expPatho">Pathophysiology</option> <option value="expTissue">Tissue</option> <option value="expTech">Technique</option> <option value="expComment">Comments</option> </optgroup> <optgroup label="Xenobiotics influencing gene expression"> <option value="xenoExpChange">Description</option> <option value="xenoExpTissue">Tissue</option> <option value="xenoExpTech">Technique</option> <option value="xenoExpComment">Comments</option> </optgroup> <optgroup label="3D structure"> <option value="pdbDesc">Description</option> </optgroup> <optgroup label="Ion channel selectivity"> <option value="selectivityComment">Comments</option> </optgroup> <optgroup label="Ion channel voltage dependence"> <option value="voltageComment">Comments</option> </optgroup> <optgroup label="Ion channel/transporter functional characteristics"> <option value="functionalChars">Functional characteristics</option> </optgroup> <optgroup label="GPCR transduction"> <option value="transductionComment">Comments</option> </optgroup> <optgroup label="NHR target gene"> <option value="targetGeneName">Name</option> <option value="targetGeneComment">Comments</option> </optgroup> <optgroup label="NHR DNA binding"> <option value="dnaBindSeq">HRE sequence</option> <option value="dnaBindComment">Comments</option> </optgroup> <optgroup label="NHR co-binding partner"> <option value="partnerName">Name</option> <option value="partnerEffect">Effect</option> <option value="partnerComment">Comments</option> </optgroup> <optgroup label="NHR co-regulator"> <option value="coregName">Name</option> <option value="coregComment">Comments</option> </optgroup> <optgroup label="Enzyme reaction"> <option value="ec">EC number</option> </optgroup> </select> </td> <td align="right" valign="top"> Limit by species: <select name="species"> <option value="none">All</option> <option value="Hs">Human</option> <option value="Mm">Mouse</option> <option value="Rn">Rat</option> </select> <br><br> Limit by target type: <select name="type"> <option value="all">All</option> <option value="GPCR">GPCRs</option> <option value="IC">Ion Channels</option> <option value="NHR">NHRs</option> <option value="ENZ">Enzymes</option> <option value="CATR">Catalytic Receptors</option> <option value="TRANS">Transporters</option> <option value="OTHER">Other proteins</option> <option value="IMMUNO">Immuno</option> </select> <br><br> <input type="hidden" name="order" value="rank"/> <input type="hidden" name="resType" value="target"/> <input type="submit" name="submit" value="Search the database"/><br/> </td> </tr> </table> </fieldset> </form> <form method="get" action="DatabaseSearchForward"> <fieldset> <h3>Wildcard name search</h3> <p> Use a wildcard search to match part of a target name by adding a <b>&#37; (percent sign)</b> as the wildcard character. </p> <input style="margin-left:10px;" type="text" size="50" maxlength="300" name="searchWildcard"/> <input type="hidden" name="order" value="rank"/> <input type="hidden" name="resType" value="target"/> <input type="submit" name="submitWildcard" value="Do wildcard search"/> <p><i>Example: <b>PIK3C<u>%</u></b> would match <b>PIK3C<u>2A</u></b>, <b>PIK3C<u>2B</u></b> etc.</i></p> </fieldset> </form> <form method="post" action="DatabaseSearchForward"> <a name="idSearch"></a> <fieldset> <h3>Search by database identifier</h3> <a style="color:white;" href="JavaScript:callRef('helpPagePopup.jsp#recIdSearch', 800, 400)" title="Click here for help"><img class="logo" style="vertical-align:baseline;" src="images/help_blue_small.png" alt="Click here for help"/></a> <table cellpadding="10"> <tr> <td align="left"> <label for="idList">Enter identifiers to search: </label> <textarea rows="10" name="searchAcc" id="idList" style="vertical-align: top;"/></textarea> </td> <td style="text-align: center; vertical-align: top;"> Select source: <select name="accTypes"> <option value="chembl">ChEMBL</option> <option value="ensembl">Ensembl</option> <option value="entrezGene">Entrez Gene</option> <option value="hgncId">HGNC Gene Id</option> <option value="hgncName">HGNC Gene Symbol</option> <option value="iuphar">IUPHAR/BPS GtoPdb Target Id</option> <option value="mgiId">MGI Gene Id</option> <option value="mgiName">MGI Gene Symbol</option> <option value="nursa">NURSA Id</option> <option value="omim">OMIM</option> <option value="orphanet">Orphanet</option> <option value="pdb">PDB code</option> <option value="refSeqN">RefSeq Nucleotide</option> <option value="refSeqP">RefSeq Protein</option> <option value="rgdId">RGD Gene Id</option> <option value="rgdName">RGD Gene Symbol</option> <option value="uniProt" selected="selected">UniProt</option> <option value="none">Unknown</option> </select> <br/> <br/> <input type="hidden" name="order" value="rank"/> <input type="submit" name="submitAcc" value="Search the database"/><br/> </td> </tr> <tr> <td style="text-align: left; padding:0px 10px;" colspan="2"> <div id="file_upload" style="margin-bottom: 10px;"> <label for="file">Or upload a file: </label> <input type="file" onchange="fileUploaded(event);" id="file"></input> </div> <small><a href="#idSearch" onclick="clearIds();">Clear</a></small> </td> </tr> </table> </fieldset> </form> <form method="get" action="DatabaseSearchForward"> <fieldset> <h3>Search for data by literature reference</h3> <a style="color:white;" href="JavaScript:callRef('helpPagePopup.jsp#recRefSearch', 800, 400)" title="Click here for help"><img class="logo" style="vertical-align:baseline;" src="images/help_blue_small.png" alt="Click here for help"/></a> <table cellpadding="10"> <tr> <td align="left" colspan="2"> Enter title keyword, author name or PubMed Id: <input type="text" size="36" maxlength="100" name="searchRef"/> </td> </tr> <tr> <td align="left"> Select field to search: <select name="refField"> <option value="refTitle">Title</option> <option value="refAuthor">Author</option> <option value="refPMID">PubMed Id</option> </select> </td> <td align="right"> <input type="hidden" name="order" value="rank"/> <input type="submit" name="submitRef" value="Search the database"/><br/> </td> </tr> </table> </fieldset> </form> <div style="padding:15px;"> <fieldset> <h3>Search for targets by sequence</h3> <a style="color:white;" href="JavaScript:callRef('helpPagePopup.jsp#blastSearch', 800, 400)" title="Click here for help"><img class="logo" style="vertical-align:baseline;" src="images/help_blue_small.png" alt="Click here for help"/></a> <p>Use our <a href="/blast">BLAST tool</a> to search for targets by sequence <a href="/blast"><img src="images_dev27082012/go.jpg"></a></p> </fieldset> </div> </div> </div> </div> <!-- ==================== GRID 16 END ==================== --> </div> <!-- ==================== CONTENT END ============================================ --> 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