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encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p> <h2 class="orangetitle">SAFFROX (ספרוקס) לשיפור מצב הרוח</h2> <p>אנו חיים בעולם מלחיץ, שלעיתים לא קל לרבים מאתנו: עומס העבודה, יוקר המחיה, מחירי הדיור והידרדרות המצב הכלכלי משפיעים על האופן שבו אנו מרגישים ומובילים לירידה במצב הרוח של ישראלים רבים. סקר של המרכז ללימודים אקדמיים ומכון פסגות מצא, שהידרדרות במצב הכלכלי מביאה ישראלים רבים למצב דכדוך. גם המגמות הטכנולוגיות, החיבור המתמיד לרשתות החברתיות והניכור שאנו חווים ביומיום הופכים את העידן שבו אנו חיים לקשה במיוחד מבחינה רגשית. זהו כנראה ההסבר לעובדה שבשנים האחרונות חלה עלייה דרמטית בכמות הישראלים, ברובם צעירים, הסובלים מחרדה ודכדוך ברמות שונות. מדו"ח של הלשכה המרכזית לסטטיסטיקה שפורסם בשנת 2016, עולה כי בקרב היהודים, 34% מבני 20 ומעלה חשו מדוכאים לעתים קרובות או מדי פעם ו-9% חשו דכדוך לעתים קרובות. במגזר הערבי תחושת הדכדוך מגיעה ל-49%. שיעור הדכדוך לרוב גבוה יותר בקרב נשים: 40% מהן חשו מדוכאות לעתים קרובות או מדי פעם, לעומת 27% מהגברים . קיימת הערכה לפיה, כ- 35% מהישראלים נוטלים תרופות לשיפור מצב הרוח (הארץ 19/11/2013 נגה ניר נאמן, הילה אלרואי). במציאות שבה יותר משליש מהאוכלוסייה בישראל נוטלים תרופות לשיפור מצב הרוח, היה זה אך מתבקש למצוא פתרון טבעי לבעיה.</p> <p>ספרוקס SAFFROX הינו תוסף תזונה המבוסס על תמצית ייחודית של תבליני זעפרן וכורכום, ובנוסף נגזרת ייחודית של חומצה פולית, מגנוקס (מגנזיום) וויטמיני B. הזעפרן מכיל את החומרים הפעילים קרוסין, וספראנאל. למרכיבים אלה מיוחסת תרומה לאיזון רמות המעבירים העצביים במוח שמשפיעים על מצב הרוח – דופמין, נוראפינפרין וסרוטונין. במחקרים שבחנו את פעילות הזעפרן בהשוואה לתרופות נוגדות דכדוך נמצא שהשפעתו דומה לשלהן, עם פחות תופעות לוואי וללא חשש מהתמכרות.</p> <p> </p> <h2 class="orangetitle">SAFFROX (ספרוקס) – המהפכה כבר כאן</h2> <p>הזעפרן נחשב ברפואה העתיקה כתבלין בעל השפעה מרגיעה ומשפרת מצב רוח. בשנים האחרונות, ניתן לזה ביסוס מדעי בעשרות מחקרים. פרסומים במרכזים רפואיים במקומות שונים בעולם הצביעו על יעילות התבלין בטיפול בדכדוך בקבוצות ניסוי. בתחילה נוסו תכשירי זעפרן אל מול פלסבו (תרופת דמה). בהמשך הושוותה השפעתם לזו של תרופות נוגדות דכדוך נפוצות, כגון פרוזאק. תוצאות המחקרים הראו כי לזעפרן יעילות דומה לזו של תרופות, וסימנו את הכיוון למהפכה הבאה בטיפול בדכדוך. בשלב הבא נקבע המינון, ונמצא שיעילות התבלין עולה כאשר מוסיפים לנוסחה רכיבים של כורכום שגם לגביו נמצא שמגביר את האפקטיביות של התרופות נוגדות הדכדוך…<br /> תמצית הזעפרן הייחודית AFFRON המצויה ב-SAFFROX – הינה מיצוי המיוצר בחברת תרופות, המבטיח כמות קבועה ומדויקת של החומרים הפעילים שבזעפרן.<br /> השימוש בזעפרן נחקר קלינית ונמצא בטוח, אינו פוגע בזיכרון, איכות השינה, ריכוז או במערכת הלב וכלי הדם. הוא אינו גורם להתמכרות ונטול תופעות לוואי. הזעפרן נמצא מתאים לשימוש בדכדוך, דכדוך לאחר לידה (כתכשיר טבעי, מותר בהנקה), חרדה, אי שקט, רוגז ותופעות פסיכוסומטיות כמו גם למצויים בתהליכי גמילה מסמים או אלכוהול.</p> <h2 class="orangetitle">ספרוקס (SAFFROX) מכיל רכיבים טבעיים מועילים נוספים</h2> <p>הדכדוך לא חולף? ייתכן שהתשובה היא חסר בוויטמין B9<br /> החומצה הפולית (שנקראת גם ויטמין B9) חיונית ליצירת המתווכים העצביים סרוטונין, נוראדרנאלין ודופאמין. לכן, מחסור בחומצה פולית עלול להוביל לירידה במצב הרוח. מניסויים מתברר כי עד 60% מהאוכלוסייה בארה"ב אינם מסוגלים להפיק תועלת מהחומצה הפולית המתקבלת מהמזון עקב תת-פעילות של אנזים מסוים, שהופך את החומצה הפולית לזמינה למערכת העצבים. השילוב של חומצה פולית בצורתה המחוזרת (L-Methylfolate) ביחד עם הזעפרן מאפשר להתגבר על בעיה זו ולהביא לשיפור במצב הרוח. מחקרים מראים שתוספת הנוסחה הייחודית עשויה לסייע אפילו לאנשים הסובלים מדכדוך עמיד לתרופות.<br /> בנוסף לרכיבים אלה, ספרוקס מכיל את ה"MAGNOX" – רכיב המגנזיום הפטנטי שמטרתו לשפר את היכולת האנרגטית וכן גם ויטמיני B6 ו – B12, שנחשבים בעלי השפעה מרגיעה במצבי סטרס.</p> <h2 class="orangetitle">הקשר בין זעפרן – לשיפור התפקוד המיני בנשים וגברים</h2> <p><strong>מעל מחצית מהמשתמשים בתרופות נגד דכדוך מדווחים על תופעות לוואי שליליות, שהנפוצות בהן הן אובדן הדחף המיני, אי הגעה לאורגזמה והעדר זיקפה.</strong><br /> בעוד שהגברים מושפעים לעיתים קרובות יותר, נשים מדווחות על תופעות לוואי חמורות יותר. מחקר שבדק את השכיחות של הפגיעה בתפקוד המיני עם שימוש בנוגדי דכדוך ממשפחת SSRI ו -Effexor מצא כי עד 73% (!!!) מהחולים סובלים מתסמינים מיניים אלה, היכולים להימשך זמן רב לאחר הפסקת הטיפול בתרופה.<br /> מצב זה הניע את המדענים לקרוא לרופאים "לשקול את ההשפעה של טיפול תרופתי על התפקוד המיני של המטופלים". למרבה הצער, לאחר שאנשים מדוכאים ואפילו אובדניים נאבקים במשך שנים עם תרופות נוגדות דכדוך שונות, כאשר הם משיגים סוף סוף הקלה יציבה עם מינון מסוים של תרופה, רופאים אינם ששים לשנות את המינון שלהם "רק" כדי למנוע את הסימפטומים המיניים. במקום זאת, רופאים רושמים תרופות נוספות שמטרתן "לקזז" את חוסר התפקוד המיני שנגרם על ידי תרופות נוגדות דכדוך. אבל לתרופות נוספות אלו תגובות שליליות משלהן.</p> <p>מחקרים שבחנו את השפעת תמצית זעפרן על התפקוד המיני, מצאו שהיא מהווה פתרון טבעי, יעיל ובטוח לנטרול ההשפעות השליליות של נוגדי דכדוך על התפקוד המיני. המטופלים (נשים וגברים כאחד) דיווחו על שיפור דרמטי בתפקוד ובתשוקה המינית.</p> <p>במחקר אקראי, כפול סמיות, גויסו 36 <strong>גברים</strong> נשואים עם הפרעת דכדוך משמעותית שתסמיניה טופלו בהצלחה באמצעות פרוזאק – אך היו להם תלונות על ירידה בתפקוד המיני. חלקם קיבלו, בנוסף למינון הרגיל של התרופה שלהם זעפרן, וחלקם קיבלו פלצבו. התפקוד המיני הוערך באמצעות מדד סטנדרטי. לאחר ארבעה שבועות בלבד, הגברים בקבוצת הפרוזאק-פלוס-זעפרן חוו שיפור משמעותי יותר בתפקוד הזיקפה ובשביעות הרצון מאשר בקבוצת הפרוזאק-פלצבו. צוות המחקר קבע כי תמצית זעפרן הוא "טיפול נסבל ויעיל" עבור הפרעות בתפקוד המיני הגברי הנגרמות על ידי Prozac.</p> <p>לאחר מכן, מדענים יצאו לקבוע אם זעפרן יכול לעזור באופן דומה (כלומר לנטרל את ההשפעות השליליות בתפקוד המיני) שחוו <strong>נשים</strong> שטופלו בתרופות נוגדות דכדוך. ב -2013 גייסו מדגם של 38 נשים, שלכולן היה דכדוך ושטופלו בפרוזאק – אך סבלו מסוגים שונים של תפקוד מיני לקוי שנגרם על ידי תרופה נוגדת דכדוך זו. במחקר כפול סמיות, חולקו הנשים באופן אקראי לשתי קבוצות שהאחת קיבלה תוספת תמצית זעפרן והשאר קיבלו פלצבו. כל המשתתפות המשיכו לקחת את המינון הרגיל של Prozac, והערכות נעשו באמצעות מדד התפקוד המיני הנשי לאחר ארבעה שבועות – למרות שעדיין נטלו את אותה תרופה נוגדת דכדוך אשר גרמה לתסמינים המיניים הלא רצויים מלכתחילה – נשים בקבוצת הזעפרן חוו שיפור משמעותי בתפקוד המיני הכולל (FSFI), עוררות, סיכה וכאב.</p> <p>נראה כי זעפרן מהווה טיפול נלווה יעיל לניטרול תופעות לוואי מיניות שנגרמות על ידי נטילת תרופות נוגדות דכדוך.</p> <h2 class="orangetitle">תמצית זעפרן והפחתת דכדוך אחרי לידה</h2> <p>לידה של תינוק חדש מביאה הרבה שמחה והתרגשות למשפחה, אבל כרוכה גם בהרבה מאמץ ושינויים באורח החיים, חוסר שינה, לחץ ודאגה לרך הנולד, כל אלו עלולות לגרום לדכדוך.<br /> דכדוך לאחר לידה הוא הפרעה במצב הרוח שעלולה לפגוע בנשים, ולעתים גם בגברים, לאחר לידת תינוק. לפי הערכות במחקרים שונים, בין 5% ל-25% מהנשים סובלות מתסמיני דכדוך במהלך ההיריון או בשנה שלאחר הלידה, ובאופן מפתיע, כך גם בין 1.2% ל-25.5% מהגברים (רובם אבות טריים) [8]. תסמיני הדכדוך מופיעים בעיקר בחודשים הראשונים שלאחר הלידה, ועלולים להימשך חודשים ספורים ואף שנה.[9] לרוב, הדכדוך מתחיל כארבעה שבועות לאחר הלידה ונמשך עד כשישה חודשים לאחר הלידה.[10] תסמיני הדכדוך שלאחר הלידה יכולים להופיע בכל זמן לאורך השנה שלאחר הלידה[11] ועשויים לכלול את התסמינים הבאים (או את חלקם):</p> <ul> <li>עצב</li> <li>ייאוש</li> <li>הערכה עצמית נמוכה</li> <li>תחושת אשמה</li> <li>תחושת חוסר אונים</li> <li>הפרעות שינה, שבאות לידי ביטוי גם כשהתינוק ישן</li> <li>הפרעות אכילה, בעיקר חוסר תיאבון וירידה במשקל</li> <li>חוסר יכולת למצוא נחמה</li> <li>תשישות</li> <li>תחושת ריקנות</li> <li>הסתגרות חברתית</li> <li>אנרגיה נמוכה או אפסית</li> <li>תחושת תסכול</li> <li>קושי לטפל בתינוק</li> <li>ליקויים בדיבור ובכתיבה</li> <li>הפגנת כעס כלפי אחרים</li> <li>חרדה מוגברת או התקפי פאניקה</li> <li>חוסר חשק מיני</li> </ul> <p>אֵם הסובלת מדכדוך אחרי לידה יכולה גם:</p> <ul> <li>להתקשות לדאוג לעצמה או לתינוק.</li> <li>לפחוד להישאר עם התינוק לבד.</li> <li>להפגין רגשות שליליים כלפי התינוק או אף לחשוב על פגיעה בו</li> <li>לסבול או להפגין מדאגנות יתר מופרזות בנוגע לתינוק, או עניין מועט בו.</li> </ul> <h2 class="bluetitle">זעפרן ודכדוך אחרי לידה</h2> <p>בחודש מרץ 2017 פורסמו תוצאות של ניסוי קליני, בו נערכה השוואה בין הבטיחות והיעילות של זעפרן לבין פלוקסטין (פרוזאק), לטיפול בדכדוך לאחר לידה בדרגת חומרה קלה עד בינונית. מתוצאות המחקר נראה כי הזעפרן היווה אלטרנטיבה בטוחה לשיפור תסמיני דכדוך לאחר הלידה, אם כי המחברים מציינים כי מספר הנבדקים שהשתתפו במחקר היה מצומצם, ונדרש מחקר נוסף בנושא [12].</p> <h2 class="orangetitle">תמצית הזעפרן לשיפור איכות השינה</h2> <p>שינה עמוקה ואיכותית היא חיונית לתפקוד תקין ומיטבי לאורך כל היום, ובעידן המודרני התובעני זוהי מטרה נכספת. נראה כי בזכות תכונותיו המיוחדות, הזעפרן מסייע להרגעת הגוף ולשינה עמוקה.<br /> אחד המרכיבים הפעילים העיקריים של זעפרן crocin,, הראה במחקר קליני השפעה חיובית על שיפור השינה. מחקרים נוספים הראו כי מטבוליט של חומר זה תורם לשיפור איכות השינה ומפחית עייפות פיזית.</p> <p>, SAFFROX (ספרוקס) מכיל בנוסף לזעפרן גם מגנזיום (MAGNOX ) וויטמין B6 . בעוד המגנזיום מסייע להרפיית השרירים, ויטמין B6 נחשב מרגיע טבעי.<br /> בסך הכול, שילוב כל המרכיבים עשוי לסייע במצבים של בעיות שינה.</p> <h2 class="orangetitle">הקשר בין זעפרן לתסמונת קדם וסתית:</h2> <p><span style="font-family: Arial, sans-serif;">תסמונת קדם וסתית (</span><span dir="LTR">PMS</span><span style="font-family: Arial, sans-serif;">), הינה אחת מהבעיות הרפואיות הנפוצות ביותר בקרב נשים בגיל הפריון עם שכיחות של 20%-40%. 3-8% מכלל הנשים יסבלו מתסמינים קשים יותר של </span><span dir="LTR">PMS</span><span style="font-family: Arial, sans-serif;"> והן מוגדרות כסובלות מ- </span><span dir="LTR">Premenstrual dysphoric disorder</span><span style="font-family: Arial, sans-serif;">. התסמונת הקדם וסתית מאופיינת בשינויים קיצוניים במצב הרוח והתנהגות של הנשים. </span><span style="font-family: Arial, sans-serif;">מדובר בשינויים גופניים ונפשיים לפני הווסת, והם משתנים מאישה לאישה וממחזור למחזור. עוצמת השינויים יכולה להיות קלה מאוד או אפילו לא מורגשת, אך היא גם עלולה לפגוע באופן משמעותי באיכות החיים. </span><br /> <span style="font-family: Arial, sans-serif;">התסמינים הנפוצים ביותר כוללים: </span><br /> 1.<span style="font: 7pt 'Times New Roman';"> </span><span style="font-family: Arial, sans-serif;">מלאות וגודש בשדיים.</span><br /> 2.<span style="font: 7pt 'Times New Roman';"> </span><span style="font-family: Arial, sans-serif;">עייפות והפרעות שינה.</span><br /> 3.<span style="font: 7pt 'Times New Roman';"> </span><span style="font-family: Arial, sans-serif;">כאבי בטן, עצירות או שילשול.</span><br /> 4.<span style="font: 7pt 'Times New Roman';"> </span><span style="font-family: Arial, sans-serif;">בחילות.</span><br /> 5.<span style="font: 7pt 'Times New Roman';"> </span><span style="font-family: Arial, sans-serif;">כאבי ראש.</span><br /> 6.<span style="font: 7pt 'Times New Roman';"> </span><span style="font-family: Arial, sans-serif;">שינויים בתאבון.</span><br /> 7.<span style="font: 7pt 'Times New Roman';"> </span><span style="font-family: Arial, sans-serif;">הרגשת כבדות ומלאות.</span><br /> 8.<span style="font: 7pt 'Times New Roman';"> </span><span style="font-family: Arial, sans-serif;">בצקות ועליה במשקל ולעיתים עצירת שתן.</span><br /> 9.<span style="font: 7pt 'Times New Roman';"> </span><span style="font-family: Arial, sans-serif;">כאבי שרירים ומפרקים.</span><br /> 10.<span style="font: 7pt 'Times New Roman';"> </span><span style="font-family: Arial, sans-serif;">מתח נפשי, דכאון, עצבנות, שינויים קיצוניים במצב הרוח, קשיי ריכוז, הופעת אקנה וולגאריס, עור שמנוני ושינויים בשיער.</span><br /> <b><span style="font-family: Arial, sans-serif;">מיצוי זעפרן לטיפול בתסמיני התסמונת הקדם וסתית (</span></b><b><span dir="LTR">PMS</span></b><b><span style="font-family: Arial, sans-serif;">).<span dir="RTL" style="font-size: 11pt; line-height: 115%; font-family: Arial, sans-serif;">המחקר הראה את יעילות הזעפרן בטפול בתסמיני התסמונת הקדם וסתית ובנוסף הפגין מיעוט תופעות לואי. דבר שעשוי להפוך את הטיפול עם זעפרן לאלטרנטיבה בטיפול בתסמיני התסמונת הקדם וסתית. </span></span></b></p> <p>References:</p> <ol> <li>G. Kell et al. Complementary Therapies in Medicine 33 (2017) 58–64</li> <li>Shahin Akhondzadeh et al. BMC Complementary and Alternative Medicine 2004, 4:12</li> <li>N. Shahmansourietal et al. , ournalofAffectiveDisorders (20013).</li> <li>A. Akhondzadeh Basti et al. , Progress in Neuro-Psychopharmacology & Biological Psychiatry 31 (2007) 439–442</li> <li>A.A. Noorbala et al. , Journal of Ethnopharmacology 97 (2005) 281–284</li> </ol> <p>ספרות:</p> <ol> <li style="text-align: right;">(1) <a title="Saffon clinical trials" href="https://www.ncbi.nlm.nih.gov/pubmed/24299602" target="_blank" rel="noopener noreferrer">Saffron (Crocus sativus L.) and major depressive disorder: a meta-analysis of randomized clinical trials.</a> Hausenblas HA, Saha D, Dubyak PJ, Anton SD.J Integr Med. 2013 Nov;11(6):377-83. doi: 10.3736/jintegrmed2013056<a href="https://www.ncbi.nlm.nih.gov/pubmed/25384672" target="_blank" rel="noopener noreferrer">.</a></li> <li style="text-align: right;"><a href="https://www.ncbi.nlm.nih.gov/pubmed/25384672" target="_blank" rel="noopener noreferrer">(2) Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action</a>.</li> <li style="text-align: right;">Lopresti AL, Drummond PD. Hum Psychopharmacol. 2014 Nov;29(6):517-27. doi: 10.1002/hup.2434. Epub 2014 Sep 22. Review.</li> <li style="text-align: right;">(3) <a href="https://www.ncbi.nlm.nih.gov/pubmed/26165367" target="_blank" rel="noopener noreferrer">A systematic review of randomized controlled trials examining the effectiveness of saffron (Crocus sativus L.) on psychological and behavioral outcomes. Hausenblas HA, Heekin K, Mutchie HL, Anton S</a>.</li> <li style="text-align: right;">J Integr Med. 2015 Jul;13(4):231-40. doi: 10.1016/S2095-4964(15)60176-5. Review.</li> <li style="text-align: right;">(4) <a href="https://www.ncbi.nlm.nih.gov/pubmed/24848002" target="_blank" rel="noopener noreferrer">Clinical Applications of Saffron (Crocus sativus) and its Constituents: A Review. Moshiri M, Vahabzadeh M, Hosseinzadeh H</a>.</li> <li style="text-align: right;">Drug Res (Stuttg). 2015 Jun;65(6):287-95. doi: 10.1055/s-0034-1375681. Epub 2014 May 21. Review.</li> <li>Paulson JF. “Focusing on depression in expectant and new fathers: prenatal and postpartum depression not limited to mothers”. <a href="http://www.psychiatrictimes.com/major-depressive-disorder/focusing-depression-expectant-and-new-fathers" target="_blank" rel="nofollow noopener">Psychiatry Times. 2010; 27(2)</a>.</li> <li><a href="http://www.cmha.ca/mental_health/postpartum-depression/" target="_blank" rel="nofollow noopener">Canadian Mental Health Association.</a> “Postpartum Depression”. Retrieved June 13th, 2010</li> <li>Miller LJ (2002). <a href="http://jamanetwork.com/journals/jama/article-abstract/194624" target="_blank" rel="nofollow noopener">"Postpartum Depression"</a> Journal of American Medical Association (JAMA) 2011; 287: 762-765. Retrieved 2011-12-15</li> <li>Miller LJ1, LaRusso EMPsychiatr Clin North Am. 2011 Mar;34(1):53-65. doi: 10.1016/j.psc.2010.11.010. Epub 2010 Dec 16 Preventing postpartum depression.</li> <li>Forman D. Nielson, P. Videbech, M. Hedegaard, J. Dalby Slavig, & N.J. Secher. "Postnatal depression: identification of women at risk". <a href="https://www.ncbi.nlm.nih.gov/pubmed/11028570" target="_blank" rel="nofollow noopener">British Journal of Obstetrics and Gynaecology (BJOG) 2000; 107 : 1210–1217</a>.</li> <li>Kashani L. et al. Comparison of Saffron versus Fluoxetine in treatment of mild to moderate postpartum depression: A double-blind, randomized clinical trial. <a href="https://www.ncbi.nlm.nih.gov/pubmed/27595298" target="_blank" rel="nofollow noopener">Pharmacopsychiatry. 2017; 50: 64-68</a>.</li> <li>Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial</li> </ol> </div> </div> </div> </div> </div> </section> <div class="elementor-element elementor-element-fa37486 e-flex e-con-boxed e-con e-parent" data-id="fa37486" data-element_type="container" id="usage_instr"> <div class="e-con-inner"> <div class="elementor-element elementor-element-9f3b2d4 elementor-widget elementor-widget-heading" data-id="9f3b2d4" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">הוראות שימוש</h2> </div> </div> <div class="elementor-element elementor-element-7d59202 e-flex e-con-boxed e-con e-child" data-id="7d59202" data-element_type="container"> <div class="e-con-inner"> <div class="elementor-element elementor-element-cc50458 e-con-full e-flex e-con e-child" data-id="cc50458" data-element_type="container"> <div class="elementor-element elementor-element-b4ff857 elementor-view-default elementor-position-top elementor-mobile-position-top elementor-widget elementor-widget-icon-box" data-id="b4ff857" data-element_type="widget" data-widget_type="icon-box.default"> <div class="elementor-widget-container"> <div class="elementor-icon-box-wrapper"> <div class="elementor-icon-box-icon"> <span class="elementor-icon elementor-animation-"> <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="512" height="512" x="0" y="0" viewBox="0 0 511.32 511.32" style="enable-background:new 0 0 512 512" xml:space="preserve" class=""><g><path d="m245.965 225.46 36.713-36.713c20.276-20.276 53.15-20.276 73.426 0 20.276 20.276 20.276 53.15 0 73.426-20.276 20.276-53.15 20.276-73.426 0l-36.713-36.713zM179.997 225.46l-36.713-36.713c-20.276-20.276-53.15-20.276-73.426 0-20.276 20.276-20.276 53.15 0 73.426 20.276 20.276 53.15 20.276 73.426 0l36.713-36.713zM179.997 225.46l33.182-33.182M212.981 258.444l33.182-33.182" 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opacity="1" class=""></path></g></svg> </span> </div> <div class="elementor-icon-box-content"> <div class="elementor-icon-box-title"> <span > מגדר </span> </div> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-67044c9 e-con-full e-flex e-con e-child" data-id="67044c9" data-element_type="container"> <div class="elementor-element elementor-element-c85b488 elementor-view-default elementor-position-top elementor-mobile-position-top elementor-widget elementor-widget-icon-box" data-id="c85b488" data-element_type="widget" data-widget_type="icon-box.default"> <div class="elementor-widget-container"> <div class="elementor-icon-box-wrapper"> <div class="elementor-icon-box-icon"> <span class="elementor-icon elementor-animation-"> <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="512" height="512" x="0" y="0" viewBox="0 0 504.615 504.615" style="enable-background:new 0 0 512 512" xml:space="preserve" class=""><g><path fill-rule="evenodd" d="M118.514 210.848a8.393 8.393 0 0 0 8.393-8.393v-67.148a8.393 8.393 0 1 0-16.786 0v67.148a8.391 8.391 0 0 0 8.393 8.393z" clip-rule="evenodd" fill="#ff7800" opacity="1" data-original="#000000" class=""></path><path d="M168.874 210.848a25.072 25.072 0 0 0 18.633-41.967c9.144-10.06 8.651-25.563-1.113-35.022-9.765-9.459-25.275-9.459-35.04 0s-10.258 24.962-1.113 35.022a25.071 25.071 0 0 0 18.633 41.967zm0-16.786a8.393 8.393 0 0 1-8.393-8.393 8.393 8.393 0 0 1 8.393-8.393 8.393 8.393 0 0 1 8.393 8.393 8.392 8.392 0 0 1-8.393 8.393zm0-50.361a8.393 8.393 0 0 1 8.393 8.393 8.393 8.393 0 0 1-8.393 8.393 8.393 8.393 0 1 1 0-16.786zM252.809 227.635h-8.393c-13.907 0-25.18 11.274-25.18 25.18 0 13.907 11.274 25.18 25.18 25.18h8.393v25.18a8.393 8.393 0 1 0 16.786 0v-58.754c.001-9.27-7.515-16.786-16.786-16.786zm-16.787 25.181a8.393 8.393 0 0 1 8.393-8.393h8.393v16.787h-8.393a8.395 8.395 0 0 1-8.393-8.394z" fill="#ff7800" opacity="1" data-original="#000000" class=""></path><path d="M429.407 277.601c26.758-95.765-14.442-197.528-100.286-247.704S134.391-6.241 64.079 64.066s-84.355 179.193-34.183 265.04 151.932 127.052 247.699 100.299c19.373 50.27 70.468 80.91 123.938 74.322s95.599-48.715 102.19-102.184c6.59-53.469-24.047-104.565-74.316-123.942zM219.235 420.684c-86.685.191-163.816-54.976-191.645-137.073s-.145-172.795 68.788-225.355 163.724-55.25 235.526-6.682 104.585 137.551 81.455 221.093a116.214 116.214 0 0 0-16.695-2.577c23.354-81.085-11.112-167.698-83.792-210.568S147.715 28.389 88.048 88.055 16.645 240.199 59.515 312.879s129.483 107.146 210.568 83.792a116.462 116.462 0 0 0 2.577 16.703 201.594 201.594 0 0 1-53.425 7.31zm117.508-139.582v-36.679c0-9.271-7.516-16.787-16.787-16.787h-8.393c-13.907 0-25.18 11.274-25.18 25.18 0 13.907 11.274 25.18 25.18 25.18h8.393v12.817a117.39 117.39 0 0 0-49.958 88.333c-73.983 23.633-154.53-6.423-194.946-72.744S44.848 154.716 99.766 99.798s140.282-65.129 206.603-24.713 96.378 120.963 72.744 194.946a116.578 116.578 0 0 0-42.37 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0-11.869-.003z" fill="#ff7800" opacity="1" data-original="#000000" class=""></path></g></g></svg> </span> </div> <div class="elementor-icon-box-content"> <div class="elementor-icon-box-title"> <span > טווח גילאים </span> </div> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-529410a e-con-full e-flex e-con e-child" data-id="529410a" data-element_type="container"> <div class="elementor-element elementor-element-9cc1160 elementor-view-default elementor-position-top elementor-mobile-position-top elementor-widget elementor-widget-icon-box" data-id="9cc1160" data-element_type="widget" data-widget_type="icon-box.default"> <div class="elementor-widget-container"> <div class="elementor-icon-box-wrapper"> <div class="elementor-icon-box-icon"> <span class="elementor-icon elementor-animation-"> <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="512" height="512" x="0" y="0" viewBox="0 0 60 60" style="enable-background:new 0 0 512 512" xml:space="preserve" class=""><g><g fill="#000" fill-rule="nonzero"><path d="M56.777 41.223c-.005 0-.013-.007-.018-.012-.454-.45-.947-.86-1.472-1.224l1.79-1.79a9.715 9.715 0 0 0-5.466-16.5C49.428 8.647 37.788-.679 24.575.038 11.363.755.8 11.287.043 24.496c-.756 13.21 8.534 24.88 21.578 27.101a9.729 9.729 0 0 0 16.516 5.55l1.854-1.854c.364.523.772 1.013 1.22 1.466.005.005.007.013.012.018s.013.007.018.012a10.994 10.994 0 0 0 15.548-15.548c-.005-.005-.007-.013-.012-.018zm-14.8 13.388a8.989 8.989 0 0 1 12.634-12.636zM57.94 31.32c0 2.052-.82 4.019-2.277 5.463l-2.181 2.181a10.938 10.938 0 0 0-11.547 1.617l-5.973-5.973 8.765-8.761a7.742 7.742 0 0 1 10.938 0 7.658 7.658 0 0 1 2.275 5.473zM24.362 43.374c-.155.155-.293.32-.436.483a17.659 17.659 0 0 1-6.035-1.812l.475-.822a1 1 0 1 0-1.732-1l-.465.8a18.29 18.29 0 0 1-5.193-5.2l.8-.463a1 1 0 1 0-1-1.732l-.818.473A17.817 17.817 0 0 1 8.048 27H9a1 1 0 0 0 0-2h-.949c.133-2.476.78-4.898 1.9-7.11l.825.476a1 1 0 1 0 1-1.732l-.828-.478a18.115 18.115 0 0 1 5.207-5.207l.478.828a1 1 0 1 0 1.732-1l-.476-.825A17.853 17.853 0 0 1 25 8.051V9a1 1 0 0 0 2 0v-.952c2.476.135 4.897.785 7.107 1.91l-.473.819a1 1 0 1 0 1.732 1l.463-.8a18.294 18.294 0 0 1 5.2 5.194l-.8.465a1 1 0 1 0 1 1.732l.821-.474a17.679 17.679 0 0 1 1.813 6.049c-.184.159-.369.317-.544.492zM2 26C1.989 13.6 11.433 3.235 23.78 2.097 36.13.959 47.31 9.422 49.565 21.616a9.732 9.732 0 0 0-3.864 1.065 19.651 19.651 0 0 0-2.3-6.454.978.978 0 0 0-.079-.227.992.992 0 0 0-.142-.161A20.3 20.3 0 0 0 36.2 8.851a.676.676 0 0 0-.458-.26 19.718 19.718 0 0 0-19.642.055.9.9 0 0 0-.1.033 1.027 1.027 0 0 0-.1.087A20.13 20.13 0 0 0 8.766 15.9a.919.919 0 0 0-.087.1.884.884 0 0 0-.033.1 19.717 19.717 0 0 0-.056 19.634.958.958 0 0 0 .089.266c.054.089.122.169.2.237a20.316 20.316 0 0 0 6.963 6.942 1 1 0 0 0 .161.142c.087.048.18.084.278.105a19.656 19.656 0 0 0 6.37 2.274 9.736 9.736 0 0 0-1.095 3.852C10.238 47.398 2.037 37.521 2 26zm34.723 29.733a7.74 7.74 0 0 1-10.947-10.945l8.771-8.767L40.524 42a10.944 10.944 0 0 0-1.556 11.491zM49 58c-2.04 0-4.02-.696-5.611-1.975l12.636-12.636A8.989 8.989 0 0 1 49 58z" fill="#ff7800" opacity="1" data-original="#000000"></path><path d="M45.293 27.293a1 1 0 1 0 1.414 1.414c2.317-2.316 4.5-1.028 4.745-.871a1 1 0 0 0 1.1-1.668 5.745 5.745 0 0 0-7.259 1.125zM26 12a1 1 0 0 0-1 1v12.412l-8.486 4.714a1 1 0 1 0 .972 1.748l9-5A1 1 0 0 0 27 26V13a1 1 0 0 0-1-1z" fill="#ff7800" opacity="1" data-original="#000000"></path></g></g></svg> </span> </div> <div class="elementor-icon-box-content"> <div class="elementor-icon-box-title"> <span > מועד נטילה </span> </div> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-92da856 e-con-full e-flex e-con e-child" data-id="92da856" data-element_type="container"> <div class="elementor-element elementor-element-c719d22 elementor-view-default elementor-position-top elementor-mobile-position-top elementor-widget elementor-widget-icon-box" data-id="c719d22" data-element_type="widget" data-widget_type="icon-box.default"> <div class="elementor-widget-container"> <div class="elementor-icon-box-wrapper"> <div class="elementor-icon-box-icon"> <span class="elementor-icon elementor-animation-"> <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="512" height="512" x="0" y="0" viewBox="0 0 512 512" style="enable-background:new 0 0 512 512" xml:space="preserve" class=""><g><path d="M125.696 125.994c-5.52 0-10 4.48-10 10s4.48 10 10 10 10-4.48 10-10-4.48-10-10-10zM215.691 312.984h-29.998v-29.998c0-5.522-4.478-10-10-10s-9.999 4.478-9.999 10v29.998h-29.998c-5.522 0-10 4.478-10 9.999s4.478 10 10 10h29.998v29.998c0 5.522 4.478 10 9.999 10s10-4.478 10-10v-29.998h29.998c5.522 0 10-4.478 10-10s-4.477-9.999-10-9.999z" fill="#ff7800" opacity="1" data-original="#000000" class=""></path><path d="M485.578 321.984c-22.105-38.286-70.981-51.389-109.274-29.279l-40.618 23.45v-86.836c0-10.735-3.55-21.388-9.999-29.998L275.69 132.66v-28.386c11.638-4.128 19.999-15.242 19.999-28.279V29.998C295.687 13.457 282.23 0 265.689 0H85.698C69.157 0 55.699 13.457 55.699 29.998v45.998c0 13.035 8.361 24.151 19.999 28.279v28.386l-50.001 66.665c-6.446 8.606-9.996 19.258-9.996 29.993v193.66c0 27.569 22.429 49.997 49.997 49.997H226.4c22.421 37.583 70.767 50.161 108.664 28.279L456.3 431.258c37.955-21.918 51.494-70.779 29.278-109.274zM75.698 29.998c0-5.514 4.486-10 9.999-10h179.991c5.514 0 10 4.486 10 10v45.998c0 5.514-4.486 9.999-10 9.999H85.698c-5.514 0-9.999-4.486-9.999-9.999V29.998zM41.701 211.319l51.996-69.326a9.999 9.999 0 0 0 2-6v-29.998h159.992v19.999h-89.995c-5.522 0-10 4.478-10 10s4.478 10 10 10h94.995l48.993 65.322c3.202 4.275 5.191 9.39 5.792 14.674H35.913c.6-5.285 2.589-10.4 5.788-14.671zm23.998 241.658c-16.541 0-29.998-13.457-29.998-29.998V412.88h181.675c-3.171 12.965-3.15 26.813.481 40.098H65.699zm159.52-59.997H35.7V245.987h279.986V327.7l-60.619 35.002c-12.639 7.301-22.855 17.694-29.848 30.278zm99.847 90.955c-28.697 16.571-65.367 6.771-81.949-21.946-16.661-28.994-6.564-65.498 21.952-81.969l54.277-31.338 59.997 103.915-54.277 31.338zM446.3 413.939l-49.637 28.659-59.998-103.917 49.638-28.656c28.716-16.578 65.373-6.761 81.955 21.957 16.655 28.862 6.527 65.508-21.958 81.957z" fill="#ff7800" opacity="1" data-original="#000000" class=""></path></g></svg> </span> </div> <div class="elementor-icon-box-content"> <div class="elementor-icon-box-title"> <span > מינון </span> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-0906b75 product-notes e-flex e-con-boxed e-con e-parent" data-id="0906b75" data-element_type="container"> <div class="e-con-inner"> <div class="elementor-element elementor-element-197b685 e-flex e-con-boxed e-con e-child" data-id="197b685" data-element_type="container"> <div class="e-con-inner"> <div class="elementor-element elementor-element-ccd297e elementor-widget elementor-widget-text-editor" data-id="ccd297e" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <ul><li>למען הסר ספק, המידע אינו מיועד להנחות את הציבור או לשמש לגביו כהמלצה או הוראה או עצה לשימוש או שינוי או הורדה של תרופה כלשהיא. ואין בו תחליף לייעוץ רפואי פרטני או אחר. הכתוב באתר אינו מהווה המלצה רפואית מוסמכת. <span lang="HE">מוצרי נווה פארמה הינם תוספי תזונה ואינם מאושרים לשימוש במצבים רפואיים, ייחוס סגולות ריפוי לתוסף תזונה אסור על פי הוראות החוק במדינת ישראל</span><span dir="LTR">.</span></li><li>המוצר אינו מהווה תחליף לטיפול רפואי או תרופתי.</li><li>נשים בהריון, נשים מניקות, אנשים הנוטלים תרופות מרשם וילדים – יש להיוועץ ברופא.</li></ul> </div> </div> </div> </div> </div> </div> </div> <footer data-elementor-type="footer" data-elementor-id="1170" class="elementor elementor-1170 elementor-location-footer" data-elementor-post-type="elementor_library"> <div class="elementor-element elementor-element-cb1ad6f e-flex e-con-boxed e-con e-parent" data-id="cb1ad6f" 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