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T-2 toxin induces cardiac fibrosis by causing metabolic disorders and up-regulating Sirt3/FoxO3α/MnSOD signaling pathway-mediated oxidative stress. <em class='incite-journal-name' onclick='ShowInCiteJournal(169368);'>J Environ Sci (China)</em> 2025;<b>150</b>:532-544. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39306426' target='_blank'>39306426</a> DOI: <a href='https://dx.doi.org/10.1016/j.jes.2024.03.001' target='_blank'>10.1016/j.jes.2024.03.001</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jes.2024.03.001','39306426', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(1);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(1);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(1);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jes.2024.03.001' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169368);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 11/16/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 02/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 03/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/25/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv1" value="10.1016/j.jes.2024.03.001" /> <div style="display: none" id="articleAbstract1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">T-2 toxin, an omnipresent environmental contaminant, poses a serious risk to the health of humans and animals due to its pronounced cardiotoxicity. This study aimed to elucidate the molecular mechanism of cardiac tissue damage by T-2 toxin. Twenty-four male Sprague-Dawley rats were orally administered T-2 toxin through gavage for 12 weeks at the dose of 0, 10, and 100 nanograms per gram body weight per day (ng/(g·day)), respectively. Morphological, pathological, and ultrastructural alterations in cardiac tissue were meticulously examined. Non-targeted metabolomics analysis was employed to analyze alterations in cardiac metabolites. The expression of the Sirt3/FoxO3α/MnSOD signaling pathway and the level of oxidative stress markers were detected. The results showed that exposure to T-2 toxin elicited myocardial tissue disorders, interstitial hemorrhage, capillary dilation, and fibrotic damage. Mitochondria were markedly impaired, including swelling, fusion, matrix degradation, and membrane damage. Metabonomics analysis unveiled that T-2 toxin could cause alterations in cardiac metabolic profiles as well as in the Sirt3/FoxO3α/MnSOD signaling pathway. T-2 toxin could inhibit the expressions of the signaling pathway and elevate the level of oxidative stress. In conclusion, the T-2 toxin probably induces cardiac fibrotic impairment by affecting amino acid and choline metabolism as well as up-regulating oxidative stress mediated by the Sirt3/FoxO3α/MnSOD signaling pathway. This study is expected to provide targets for preventing and treating T-2 toxin-induced cardiac fibrotic injury. </div> <a href="javascript:ShowArticleAbstract(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cardiac+fibrosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cardiac fibrosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Environmental+contaminant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Environmental contaminant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Metabolic+disorder%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Metabolic disorder</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxidative+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxidative stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sirt3%2fFoxO3%ce%b1%2fMnSOD+signaling+pathway%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sirt3/FoxO3α/MnSOD signaling pathway</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22T-2+toxin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">T-2 toxin</a></li></ul> <a href="javascript:ShowArticleKeywords(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22T-2+Toxin%2ftoxicity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">T-2 Toxin/toxicity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxidative+Stress%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxidative Stress/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Forkhead+Box+Protein+O3%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Forkhead Box Protein O3/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Superoxide+Dismutase%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Superoxide Dismutase/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fibrosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fibrosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Metabolic+Diseases%2fchemically+induced%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Metabolic Diseases/chemically induced</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Up-Regulation%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Up-Regulation/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sirtuin+3%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sirtuin 3/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myocardium%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myocardium/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myocardium%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myocardium/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(1);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow2"> <td style="min-width: 40px; text-align: center;"> 2 </td> <td> <div id="citation2" class="article-citation"> <b>Liang X</b>, Wang Z, Wang S, Ruan F, Zhang Y, Shao D, Liu X, Chen F, Shi X. Magnetic mesoporous silica nanoparticles loaded with peptides for the targeted repair of cavernous nerve injury underlying erectile dysfunction. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>314</b>:122811. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39265373' target='_blank'>39265373</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122811' target='_blank'>10.1016/j.biomaterials.2024.122811</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122811','39265373', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(2);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(2);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(2);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122811' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/14/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv2" value="10.1016/j.biomaterials.2024.122811" /> <div style="display: none" id="articleAbstract2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Erectile dysfunction (ED) is a common male sexual disorder characterized by repeated or persistent difficulty in achieving or maintaining an erection. It can arise from various factors, with cavernous nerve injury (CNI) from radical prostatectomy being a predominant cause of iatrogenic ED, posing significant clinical concerns. The complexity of cavernous tissue damage in CNI-induced ED (CNIED) often results in poor efficacy and resistance to conventional vascular ED treatments. To address CNI-induced ED, this study developed a system of magnetic mesoporous silica nanoparticles (MSNs) loaded with peptides for targeted treatment. Core-shell Fe3O4-coated MSNs were used as drug carriers and loaded with RADA16-I/RAD-RGI peptides (PD) to create a neurotrophic microenvironment to treat peripheral nerve defects. Furthermore, the neuro-targeting peptide HLNILSTLWKYR (PT) was grafted onto MSNs. The in vivo therapeutic effect was evaluated using a rat bilateral cavernous nerve injury (BCNI) model. The results showed that the neuro-targeted Fe3O4@SiO2-PT-PD nanoparticles significantly promoted regeneration of the cavernous nerve and restored erectile function. This promising strategy offers significant clinical potential for treating CNI-induced ED. Nanomedicine technology has the potential to not only improve treatment outcomes but also reduce side effects in healthy cells, paving the way for more accurate targeted repair of cavernous nerve damage. </div> <a href="javascript:ShowArticleAbstract(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cavernous+nerve+injury%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cavernous nerve injury</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Erectile+dysfunction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Erectile dysfunction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnetic+mesoporous+nanoparticles%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnetic mesoporous nanoparticles</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nerve+regeneration%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nerve regeneration</a></li></ul> <a href="javascript:ShowArticleKeywords(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Erectile+Dysfunction%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Erectile Dysfunction/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Erectile+Dysfunction%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Erectile Dysfunction/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Silicon+Dioxide%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Silicon Dioxide/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Peptides%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Peptides/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Peptides%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Peptides/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Penis%2finnervation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Penis/innervation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Porosity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Porosity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nerve+Regeneration%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nerve Regeneration/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnetite+Nanoparticles%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnetite Nanoparticles/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nanoparticles%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nanoparticles/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Peripheral+Nerve+Injuries%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Peripheral Nerve Injuries/therapy</a></li></ul> <a href="javascript:ShowArticleMeSH(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(2);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow3"> <td style="min-width: 40px; text-align: center;"> 3 </td> <td> <div id="citation3" class="article-citation"> <b>Wei X</b>, Wang L, Xing Z, Chen P, He X, Tuo X, Su H, Zhou G, Liu H, Fan Y. Glutamine synthetase accelerates re-endothelialization of vascular grafts by mitigating endothelial cell dysfunction in a rat model. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>314</b>:122877. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39378796' target='_blank'>39378796</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122877' target='_blank'>10.1016/j.biomaterials.2024.122877</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122877','39378796', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(3);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(3);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(3);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122877' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/10/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv3" value="10.1016/j.biomaterials.2024.122877" /> <div style="display: none" id="articleAbstract3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Endothelial cell (EC) dysfunction within the aorta has long been recognized as a prominent contributor to the progression of atherosclerosis and the subsequent failure of vascular graft transplantation. However, the direct relationship between EC dysfunction and vascular remodeling remains to be investigated. In this study, we sought to address this knowledge gap by employing a strategy involving the release of glutamine synthetase (GS), which effectively activated endothelial metabolism and mitigates EC dysfunction. To achieve this, we developed GS-loaded small-diameter vascular grafts (GSVG) through the electrospinning technique, utilizing dual-component solutions consisting of photo-crosslinkable hyaluronic acid and polycaprolactone. Through an in vitro model of oxidized low-density lipoprotein-induced injury in human umbilical vein endothelial cells (HUVECs), we provided compelling evidence that the GSVG promoted the restoration of motility, angiogenic sprouting, and proliferation in dysfunctional HUVECs by enhancing cellular metabolism. Furthermore, the sequencing results indicated that these effects were mediated by miR-122-5p-related signaling pathways. Remarkably, the GSVG also exhibited regulatory capabilities in shifting vascular smooth muscle cells towards a contractile phenotype, mitigating inflammatory responses and thereby preventing vascular calcification. Finally, our data demonstrated that GS incorporation significantly enhanced re-endothelialization of vascular grafts in a ferric chloride-injured rat model. Collectively, our results offer insights into the promotion of re-endothelialization in vascular grafts by restoring dysfunctional ECs through the augmentation of cellular metabolism. </div> <a href="javascript:ShowArticleAbstract(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Atherosclerosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Atherosclerosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cellular+metabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cellular metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endothelial+cell+dysfunction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endothelial cell dysfunction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glutamine+synthetase%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glutamine synthetase</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Small-vascular+graft%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Small-vascular graft</a></li></ul> <a href="javascript:ShowArticleKeywords(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Human+Umbilical+Vein+Endothelial+Cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Human Umbilical Vein Endothelial Cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glutamate-Ammonia+Ligase%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glutamate-Ammonia Ligase/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Blood+Vessel+Prosthesis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Blood Vessel Prosthesis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Proliferation%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Proliferation/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endothelial+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endothelial Cells/metabolism</a></li></ul> <a href="javascript:ShowArticleMeSH(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(3);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow4"> <td style="min-width: 40px; text-align: center;"> 4 </td> <td> <div id="citation4" class="article-citation"> <b>Yin L</b>, Wen Y, Liang Z, Guan Z, Yu X, Xu J, Wang S, Liu W. Lung function and blood gas of <span class="highlight-field">rats</span> after different protocols of hypobaric exposure. <em class='incite-journal-name' onclick='ShowInCiteJournal(167990);'>Med Gas Res</em> 2025;<b>15</b>:180-187. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39436190' target='_blank'>39436190</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515060' target='_blank'>PMC11515060</a> DOI: <a href='https://dx.doi.org/10.4103/mgr.medgasres-d-24-00039' target='_blank'>10.4103/mgr.medgasres-d-24-00039</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.4103/mgr.medgasres-d-24-00039','39436190', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(4);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(4);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(4);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.4103/mgr.medgasres-d-24-00039' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(167990);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/23/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv4" value="10.4103/mgr.medgasres-d-24-00039" /> <div style="display: none" id="articleAbstract4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">High-altitude pulmonary edema (HAPE) is a common disease observed in climbers, skiers and soldiers who ascend to high altitudes without previous acclimatization. Thus, a reliable and reproducible animal model that can mimic the mechanisms of pathophysiologic response in humans is crucial for successful investigations. Our results showed that exposure to 4500 m for 2 days had little influence on lung function or blood gas, and exposure to 6000 m for 2 or 3 days could change lung function and blood gas, but most parameters returned to nearly normal levels within 48 hours. This study indicates that exposure to 6000 m for 3 days may induce evident lung edema and significantly alter lung function and blood gas, which may mimic HAPE in clinical practice. Thus, this animal model of HAPE may be used in future studies on HAPE. </div> <a href="javascript:ShowArticleAbstract(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22animal+model%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">animal model</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22arterial+oxygen+pressure%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">arterial oxygen pressure</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22blood+gas%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">blood gas</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22frequency+of+breathing%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">frequency of breathing</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22hemoglobin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">hemoglobin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22high-altitude+pulmonary+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">high-altitude pulmonary edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22lung+function%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">lung function</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22oxygen+saturation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">oxygen saturation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22rat%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">rat</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22tidal+volume%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">tidal volume</a></li></ul> <a href="javascript:ShowArticleKeywords(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lung%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lung</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Blood+Gas+Analysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Blood Gas Analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Altitude+Sickness%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Altitude Sickness/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Altitude+Sickness%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Altitude Sickness/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Altitude%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Altitude</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypertension%2c+Pulmonary%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypertension, Pulmonary/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Respiratory+Function+Tests%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Respiratory Function Tests</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pulmonary+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pulmonary Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pulmonary+Edema%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pulmonary Edema/blood</a></li></ul> <a href="javascript:ShowArticleMeSH(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(4);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow5"> <td style="min-width: 40px; text-align: center;"> 5 </td> <td> <div id="citation5" class="article-citation"> <b>Chen W</b>, Zhang Y, Miao G, Ying Y, Ren Z, Sun X, Cai J, Shen H, Lu H. The augment effects of magnesium hydride on the lipid lowering effect of atorvastatin: an in vivo and in vitro investigation. <em class='incite-journal-name' onclick='ShowInCiteJournal(167990);'>Med Gas Res</em> 2025;<b>15</b>:148-155. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39436189' target='_blank'>39436189</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515074' target='_blank'>PMC11515074</a> DOI: <a href='https://dx.doi.org/10.4103/mgr.medgasres-d-23-00047' target='_blank'>10.4103/mgr.medgasres-d-23-00047</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.4103/mgr.medgasres-d-23-00047','39436189', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(5);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(5);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(5);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.4103/mgr.medgasres-d-23-00047' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(167990);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 11/22/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 12/18/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 02/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/23/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv5" value="10.4103/mgr.medgasres-d-23-00047" /> <div style="display: none" id="articleAbstract5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">There is strong evidence connecting increased serum lipid levels to cardiovascular disorders, including atherosclerosis. Statins is prescribed as the primary medication to decrease lipid levels. Recent research has demonstrated that hydrogen possesses anti-inflammatory and antioxidant properties by modulating the expression of peroxisome proliferator-activated receptor gamma coactivator-1α, ultimately leading to the preservation of lipid homeostasis. Magnesium hydride (MgH2) is a prolonged stable hydrogen storage medium, which can be utilized to investigate its synergistic lipid-lowering effect with statins and its detailed molecular mechanism, both in vivo and in vitro. To ascertain the safety and efficacy of MgH2, we executed a comprehensive research of its influence on both physiological and pathological metrics. We noted a substantial diminution in lipid levels when MgH2 was integrated with atorvastatin, as attested by oil red staining. Furthermore, we scrutinized the regulatory effect of MgH2 on cytochrome P450 3A, which is a metabolic enzyme of statins, and discovered that it could be reduced by the MgH2. Concluding from our results, we propose that MgH2 inhibits the expression of cytochrome P450 3A in the liver and exerts an auxiliary lipid-lowering effect by increasing the blood concentration of statins. By augmenting our comprehension of MgH2's role in ameliorating lipid metabolism, we aspire to develop more promising therapies in the future. </div> <a href="javascript:ShowArticleAbstract(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22atorvastatin%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">atorvastatin</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22blood+lipids%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">blood lipids</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cholesterol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cholesterol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cyp3a%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cyp3a</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22high-fat+diet%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">high-fat diet</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22hydrogen%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">hydrogen</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22magnesium+hydride%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">magnesium hydride</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22triglycerides%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">triglycerides</a></li></ul> <a href="javascript:ShowArticleKeywords(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Atorvastatin%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Atorvastatin/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogen%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogen/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogen%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogen/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lipids%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lipids/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnesium+Compounds%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnesium Compounds/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnesium+Compounds%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnesium Compounds/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lipid+Metabolism%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lipid Metabolism/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Liver%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Liver/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Drug+Synergism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Drug Synergism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypolipidemic+Agents%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypolipidemic Agents/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypolipidemic+Agents%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypolipidemic Agents/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypolipidemic+Agents%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypolipidemic Agents/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li></ul> <a href="javascript:ShowArticleMeSH(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(5);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow6"> <td style="min-width: 40px; text-align: center;"> 6 </td> <td> <div id="citation6" class="article-citation"> <b>Letko Khait N</b>, Zuccaro S, Abdo D, Cui H, Siu R, Ho E, Morshead CM, Shoichet MS. Redesigned chondroitinase ABC degrades inhibitory chondroitin sulfate proteoglycans in vitro and in vivo in the stroke-injured rat brain. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>314</b>:122818. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39260032' target='_blank'>39260032</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122818' target='_blank'>10.1016/j.biomaterials.2024.122818</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122818','39260032', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(6);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(6);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(6);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122818' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/13/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv6" value="10.1016/j.biomaterials.2024.122818" /> <div style="display: none" id="articleAbstract6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Injuries to the central nervous system, such as stroke and traumatic spinal cord injury, result in an aggregate scar that both limits tissue degeneration and inhibits tissue regeneration. The aggregate scar includes chondroitin sulfate proteoglycans (CSPGs), which impede cell migration and axonal outgrowth. Chondroitinase ABC (ChASE) is a potent yet fragile enzyme that degrades CSPGs, and thus may enable tissue regeneration. ChASE37, with 37-point mutations to the native enzyme, has been shown to be more stable than ChASE, but its efficacy has never been tested. To answer this question, we investigated the efficacy of ChASE37 first in vitro using human cell-based assays and then in vivo in a rodent model of stroke. We demonstrated ChASE37 degradation of CSPGs in vitro and the consequent cell adhesion and axonal sprouting now possible using human induced pluripotent stem cell (hiPSC)-derived neurons. To enable prolonged release of ChASE37 to injured tissue, we expressed it as a fusion protein with a Src homology 3 (SH3) domain and modified an injectable, carboxymethylcellulose (CMC) hydrogel with SH3-binding peptides (CMC-bp) using inverse electron-demand Diels-Alder chemistry. We injected this affinity release CMC-bp/SH3-ChASE37 hydrogel epicortically to endothelin-1 stroke-injured rats and confirmed bioactivity via degradation of CSPGs and axonal sprouting in and around the lesion. With CSPG degradation shown both in vitro by greater cell interaction and in vivo with local delivery from a sustained release formulation, we lay the foundation to test the potential of ChASE37 and its delivery by local affinity release for tissue regeneration after stroke. </div> <a href="javascript:ShowArticleAbstract(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aggregate+scar%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aggregate scar</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chondroitinase+ABC%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chondroitinase ABC</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Human+induced+pluripotent+stem+cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Human induced pluripotent stem cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogel%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogel</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stroke%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stroke</a></li></ul> <a href="javascript:ShowArticleKeywords(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chondroitin+ABC+Lyase%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chondroitin ABC Lyase/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chondroitin+Sulfate+Proteoglycans%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chondroitin Sulfate Proteoglycans/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stroke%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stroke/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stroke%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stroke/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Induced+Pluripotent+Stem+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Induced Pluripotent Stem Cells/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Induced+Pluripotent+Stem+Cells%2fcytology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Induced Pluripotent Stem Cells/cytology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/drug effects</a></li></ul> <a href="javascript:ShowArticleMeSH(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(6);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow7"> <td style="min-width: 40px; text-align: center;"> 7 </td> <td> <div id="citation7" class="article-citation"> <b>Liu L</b>, Ding M, Zheng M, Xu G, Gao L, Yang W, Wei Z, Shang J, Wang L, Wang H, Gao F. Transformable peptide blocks NF-κB/IκBα pathway through targeted coating IκBα against rheumatoid arthritis. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>314</b>:122839. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39288618' target='_blank'>39288618</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122839' target='_blank'>10.1016/j.biomaterials.2024.122839</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122839','39288618', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(7);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(7);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(7);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122839' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/28/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/19/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv7" value="10.1016/j.biomaterials.2024.122839" /> <div style="display: none" id="articleAbstract7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Rheumatoid arthritis (RA) is an autoimmune disease characterized by destructive effects. Although current therapies utilizing antibodies against inflammatory cytokines have shown some success, the inhibition of a single inflammatory molecule may not suffice to impede the progression of RA due to the intricate pathogenesis involving multiple molecules. In this study, we have developed an intelligent transformable peptide, namely BP-FFVLK-DSGLDSM (BFD). BFD has the ability to self-assemble into spherical nanoparticles in water or in the blood circulation to facilitate their delivery and distribution. When endocytosed into immune cells, BFD can identify and attach to phosphorylation sites on IκBα and in situ transform into a nanofibrous network coating NF-κB/IκBα complexes, blocking the phosphorylation and degradation of IκBα. As a result, BFD enables decreasing expression of proinflammatory mediators. In the present study, we demonstrate that BFD exhibits notable efficacy in alleviating arthritis-related manifestations, such as joints and tissues swelling, as well as bone and cartilage destruction on the collagen-induced arthritis (CIA) rat model. The investigation of intracellular biodistribution, phosphorylation of IκBα, and cytokine detection in culture medium supernatant, joint tissue, and serum exhibits strong associations with therapeutic outcomes. The utilization of transformable peptide presents a novel approach for the management of inflammatory diseases. </div> <a href="javascript:ShowArticleAbstract(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NF-%ce%baB%2fI%ce%baB%ce%b1+pathway%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NF-κB/IκBα pathway</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Phosphorylation+of+I%ce%baB%ce%b1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Phosphorylation of IκBα</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rheumatoid+arthritis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rheumatoid arthritis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transformable+peptide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transformable peptide</a></li></ul> <a href="javascript:ShowArticleKeywords(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NF-kappa+B%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NF-kappa B/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Arthritis%2c+Rheumatoid%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Arthritis, Rheumatoid/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Arthritis%2c+Rheumatoid%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Arthritis, Rheumatoid/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NF-KappaB+Inhibitor+alpha%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NF-KappaB Inhibitor alpha/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Peptides%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Peptides/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Phosphorylation%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Phosphorylation/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Arthritis%2c+Experimental%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Arthritis, Experimental/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Arthritis%2c+Experimental%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Arthritis, Experimental/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Arthritis%2c+Experimental%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Arthritis, Experimental/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytokines%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytokines/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RAW+264.7+Cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RAW 264.7 Cells</a></li></ul> <a href="javascript:ShowArticleMeSH(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(7);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow8"> <td style="min-width: 40px; text-align: center;"> 8 </td> <td> <div id="citation8" class="article-citation"> <b>Zhao F</b>, Jia Z, Zhang L, Liu G, Li J, Zhao J, Xie Y, Chen L, Jiang H, He W, Wang A, Peng J, Zheng Y. A MnO<sub>2</sub> nanosheets doping double crosslinked hydrogel for cartilage defect repair through alleviating inflammation and guiding chondrogenic differentiation. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>314</b>:122875. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39454507' target='_blank'>39454507</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122875' target='_blank'>10.1016/j.biomaterials.2024.122875</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122875','39454507', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(8);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(8);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(8);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122875' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/28/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv8" value="10.1016/j.biomaterials.2024.122875" /> <div style="display: none" id="articleAbstract8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The inflammatory microenvironment and inferior chondrogenesis are major symptoms after cartilage defect. Although various modifications strategies associated with hydrogels exhibit remarkable capacity of pro-cartilage regeneration, the adverse effect by prolonging inflammation is still formidable to hamper potential biomedical applications of different hydrogel implants. Herein, inspired by the repair microenvironment of articular cartilage defects, an injectable, immunomodulatory, and chondrogenic L-MNS-CMDA hydrogel is prepared through grafting vinyl and catechol groups to chitosan macromolecules using amide reaction, then further loading MnO2 nanosheets (MNS). The double crosslinking of photopolymerization and catechol oxidative polymerization endows L-MNS-CMDA hydrogel with preferable mechanical property, affording a suitable mechanical support for cartilage defect repair. Additionally, the robust tissue adhesion capability stemming from catechol groups guarantees the long-term retention of the hydrogel in the defect site. Meanwhile, L-MNS-CMDA hydrogel decomposes exogenous and intracellular H2O2 into O2 and H2O, to effectively alleviate cellular oxidative stress caused by long-term hypoxia. Under the synergies of catechol groups and MNS, L-MNS-CMDA hydrogel not only inhibits macrophages polarizing into M1 phenotype, but encourages them turn into M2 phenotype, thereby, reconstructing an immunization friendly microenvironment to ultimately enhance cartilage regeneration. Predictably, the hydrogel markedly induces rat bone marrow mesenchymal stem cells differentiating into chondrocytes by expressing abundant glycosaminoglycan and type II collagen. A cartilage defect model of rat knee joint indicates that L-MNS-CMDA hydrogel visually regulate the early inflammatory response of post-implantation, and facilitate cartilage regeneration and recovery of joint function after 12 weeks of post-implantation. All in all, this multifunctional L-MNS-CMDA hydrogel exhibits superior immunomodulatory and chondrogenic properties, holding immense clinical potential in the treatment of cartilage defects. </div> <a href="javascript:ShowArticleAbstract(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cartilage+defect%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cartilage defect</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chondrogenic+property%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chondrogenic property</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Immunomodulatory%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Immunomodulatory</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammatory+microenvironment%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammatory microenvironment</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22MnO(2)+nanosheets%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MnO(2) nanosheets</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tissue+adhesion%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tissue adhesion</a></li></ul> <a href="javascript:ShowArticleKeywords(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chondrogenesis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chondrogenesis/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Differentiation%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Differentiation/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogels%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogels/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxides%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxides/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Manganese+Compounds%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Manganese Compounds/chemistry</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chondrocytes%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chondrocytes/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chondrocytes%2fcytology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chondrocytes/cytology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cross-Linking+Reagents%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cross-Linking Reagents/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Regeneration%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Regeneration/drug effects</a></li></ul> <a href="javascript:ShowArticleMeSH(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(8);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow9"> <td style="min-width: 40px; text-align: center;"> 9 </td> <td> <div id="citation9" class="article-citation"> <b>Mu L</b>, Dong R, Li C, Chen J, Huang Y, Li T, Guo B. ROS responsive conductive microspheres loaded with salvianolic acid B as adipose derived stem cell carriers for acute myocardial infarction treatment. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>314</b>:122849. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39357150' target='_blank'>39357150</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122849' target='_blank'>10.1016/j.biomaterials.2024.122849</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122849','39357150', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(9);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(9);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(9);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122849' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv9" value="10.1016/j.biomaterials.2024.122849" /> <div style="display: none" id="articleAbstract9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Stem cell therapy is currently the most promising strategy for the treatment of myocardial infarction. However, the development of injectable cell carriers that can scavenge reactive oxygen species (ROS) in the infarct zone to improve transplanted cell survival remains a challenge. Here, we developed a ROS responsive conductive microsphere based on chitosan (CS) and dextran (DEX) with 4-formylphenylboronic acid (4-FPBA) as a cross-linking agent and the addition of graphite oxide (GO) and the anti-inflammatory agent salvianolic acid B (SalB), as a cell delivery carrier for myocardial infarction. These microspheres were crosslinked by dual dynamic networks of Schiff base and phenylborate bonds. The relationship between CS concentration and microsphere particle size, as well as the biocompatibility, ROS responsiveness, anti-inflammatory properties, and effects on myogenic differentiation of H9C2 cells were fully investigated. The microspheres exhibit good biocompatibility, proliferation promoting, differentiation promoting, antioxidant, and anti-inflammatory properties. When applied to mice myocardial infarction models, the ROS responsive conductive microspheres loaded with SalB and adipose derived stem cells (ADSC) exhibited excellent in vivo repair ability. In addition, they reduced myocardial fibrosis and promoted ventricular wall regeneration by promoting the expression of Connexin 43 (Cx43) and CD31, ultimately reshaping the infarcted myocardium, suggesting their great potential as cell delivery carriers for myocardial infarction treatment. </div> <a href="javascript:ShowArticleAbstract(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+carrier%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell carrier</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Conductivity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Conductivity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microspheres%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microspheres</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myocardial+infarction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myocardial infarction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ROS+responsiveness%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ROS responsiveness</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stem+cell+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stem cell therapy</a></li></ul> <a href="javascript:ShowArticleKeywords(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myocardial+Infarction%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myocardial Infarction/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microspheres%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microspheres</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Benzofurans%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Benzofurans/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Benzofurans%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Benzofurans/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reactive+Oxygen+Species%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reactive Oxygen Species/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adipose+Tissue%2fcytology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adipose Tissue/cytology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stem+Cells%2fcytology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stem Cells/cytology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stem+Cells%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stem Cells/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stem+Cell+Transplantation%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stem Cell Transplantation/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Line%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Line</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chitosan%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chitosan/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Differentiation%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Differentiation/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Electric+Conductivity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Electric Conductivity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depsides%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depsides</a></li></ul> <a href="javascript:ShowArticleMeSH(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(9);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow10"> <td style="min-width: 40px; text-align: center;"> 10 </td> <td> <div id="citation10" class="article-citation"> <b>Bi S</b>, He C, Zhou Y, Liu R, Chen C, Zhao X, Zhang L, Cen Y, Gu J, Yan B. Versatile conductive hydrogel orchestrating neuro-immune microenvironment for rapid diabetic wound healing through peripheral nerve regeneration. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>314</b>:122841. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39293307' target='_blank'>39293307</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122841' target='_blank'>10.1016/j.biomaterials.2024.122841</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122841','39293307', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(10);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(10);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(10);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122841' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/20/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv10" value="10.1016/j.biomaterials.2024.122841" /> <div style="display: none" id="articleAbstract10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Diabetic wound (DW), notorious for prolonged healing processes due to the unregulated immune response, neuropathy, and persistent infection, poses a significant challenge to clinical management. Current strategies for treating DW primarily focus on alleviating the inflammatory milieu or promoting angiogenesis, while limited attention has been given to modulating the neuro-immune microenvironment. Thus, we present an electrically conductive hydrogel dressing and identify its neurogenesis influence in a nerve injury animal model initially by encouraging the proliferation and migration of Schwann cells. Further, endowed with the synergizing effect of near-infrared responsive release of curcumin and nature-inspired artificial heterogeneous melanin nanoparticles, it can harmonize the immune microenvironment by restoring the macrophage phenotype and scavenging excessive reactive oxygen species. This in-situ formed hydrogel also exhibits mild photothermal therapy antibacterial efficacy. In the infected DW model, this hydrogel effectively supports nerve regeneration and mitigates the immune microenvironment, thereby expediting the healing progress. The versatile hydrogel exhibits significant therapeutic potential for application in DW healing through fine-tuning the neuro-immune microenvironment. </div> <a href="javascript:ShowArticleAbstract(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Curcumin+release%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Curcumin release</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diabetic+wounds%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diabetic wounds</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogel+dressing%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogel dressing</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nerve+repair%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nerve repair</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuro-immune+microenvironmental+modulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuro-immune microenvironmental modulation</a></li></ul> <a href="javascript:ShowArticleKeywords(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogels%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogels/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Wound+Healing%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Wound Healing/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nerve+Regeneration%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nerve Regeneration/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diabetes+Mellitus%2c+Experimental%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diabetes Mellitus, Experimental/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Curcumin%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Curcumin/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Curcumin%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Curcumin/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Curcumin%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Curcumin/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Schwann+Cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Schwann Cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Electric+Conductivity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Electric Conductivity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cellular+Microenvironment%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cellular Microenvironment/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Proliferation%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Proliferation/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-Bacterial+Agents%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-Bacterial Agents/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-Bacterial+Agents%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-Bacterial Agents/therapeutic use</a></li></ul> <a href="javascript:ShowArticleMeSH(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(10);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow11"> <td style="min-width: 40px; text-align: center;"> 11 </td> <td> <div id="citation11" class="article-citation"> <b>Ben Amara H</b>, Martinez DC, Iskhakova K, Emanuelsson L, Norlindh B, Johansson Loo A, Wieland DCF, Zeller-Plumhoff B, Willumeit-Römer R, Plocinski T, Swieszkowski W, Shah FA, Palmquist A, Omar O, Thomsen P. Multifaceted bone response to immunomodulatory magnesium implants: Osteopromotion at the interface and adipogenesis in the bone marrow. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>314</b>:122779. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39305536' target='_blank'>39305536</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122779' target='_blank'>10.1016/j.biomaterials.2024.122779</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122779','39305536', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(11);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(11);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(11);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122779' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/10/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv11" value="10.1016/j.biomaterials.2024.122779" /> <div style="display: none" id="articleAbstract11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Orthopedic implants made of biodegradable magnesium (Mg) provide an alternative to nondegradable implants for fracture repair. Widely reported to be pro-osteogenic, Mg implants are also believed to be anti-inflammatory and anti-osteoclastic, but this is difficult to reconcile with the early clinical inflammation observed around these implants. Here, by surveying implant healing in a rat bone model, we determined the cellular responses and structural assembly of bone correlated with the surface changes of Mg implants inherent in degradation. We show that, compared to titanium, both high-purity (99.998 %) and clinical-grade, rare earth-alloyed (MgYREZr) Mg implants create an initial, transient proinflammatory environment that facilitates inducible nitric oxide synthase-mediated macrophage polarization, osteoclastogenesis, and neoangiogenesis programs. While this immunomodulation subsequently reinforces reparative osteogenesis at the surface of both Mg implants, the faster degradation of high-purity Mg implants, but not MgYREZr implants, elicits a compositional alteration in the interfacial bone and a previously unknown proadipogenic response with persistent low-grade inflammation in the surrounding bone marrow. Beyond the need for rigorous tailoring of Mg implants, these data highlight the need to closely monitor osseointegration not only at the immediate implant surface but also in the peri-implant bone and adjacent bone marrow. </div> <a href="javascript:ShowArticleAbstract(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adipose+tissue%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adipose tissue</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biodegradable+implants%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biodegradable implants</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bone-implant+interface%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bone-implant interface</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Inflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Inflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnesium%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnesium</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osseointegration%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osseointegration</a></li></ul> <a href="javascript:ShowArticleKeywords(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnesium%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnesium/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnesium%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnesium/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adipogenesis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adipogenesis/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osteogenesis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osteogenesis/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bone+Marrow%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bone Marrow/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bone-Implant+Interface%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bone-Implant Interface</a></li></ul> <a href="javascript:ShowArticleMeSH(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(11);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow12"> <td style="min-width: 40px; text-align: center;"> 12 </td> <td> <div id="citation12" class="article-citation"> <b>Bezold MG</b>, Dollinger BR, DeJulius CR, Keech MC, Hanna AR, Kittel AR, Yu F, Gupta MK, D'Arcy R, Brunger JM, Duvall CL. Shear-thinning hydrogel for allograft cell transplantation and externally controlled transgene expression. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>314</b>:122812. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39288619' target='_blank'>39288619</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122812' target='_blank'>10.1016/j.biomaterials.2024.122812</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122812','39288619', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(12);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(12);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(12);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122812' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/20/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/19/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv12" value="10.1016/j.biomaterials.2024.122812" /> <div style="display: none" id="articleAbstract12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">This work establishes the design of a fully synthetic, shear-thinning hydrogel platform that is injectable and can isolate engineered, allogeneic cell therapies from the host. We utilized RAFT to generate a library of linear random copolymers of N,N-dimethylacrylamide (DMA) and 2-vinyl-4,4-dimethyl azlactone (VDMA) with variable mol% VDMA and degree of polymerization. Poly(DMA-co-VDMA) copolymers were subsequently modified with either adamantane (Ad) or β-cyclodextrin (Cd) through amine-reactive VDMA to prepare hydrogel precursor macromers containing complementary guest-host pairing pendant groups that, when mixed, form shear-thinning hydrogels. Rheometric evaluation of the hydrogel library enabled identification of lead macromer structures comprising 15 mol% pendants (Ad or Cd) and a degree of polymerization of 1000; mixing of these Ad and Cd functionalized precursors yielded hydrogels possessing storage modulus above 1000 Pa, tan(δ) values below 1 and high yield strain, which are target characteristics of robust but injectable shear-thinning gels. This modular system proved amenable to nanoparticle integration with surface-modified nanoparticles displaying Ad. The addition of the Ad-functionalized nanoparticles simultaneously improved mechanical properties of the hydrogels and enabled extended hydrogel retention of a model small molecule in vivo. In studies benchmarking against alginate, a material traditionally used for cell encapsulation, the lead hydrogel showed significantly less fibrous encapsulation in a subcutaneous implant site. Finally, this platform was utilized to encapsulate and extend in vivo longevity of inducible transgene-engineered mesenchymal stem cells in an allogeneic transplant model. The hydrogels remained intact and blocked infiltration by host cells, consequently extending the longevity of grafted cell function relative to a benchmark, shear-thinning hyaluronic acid-based gel. In sum, the new synthetic, shear-thinning hydrogel system presented here shows potential for further development as an injectable platform for delivery and in situ drug modulation of allograft and engineered cell therapies. </div> <a href="javascript:ShowArticleAbstract(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Allograft+transplantation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Allograft transplantation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+encapsulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell encapsulation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Guest-host+chemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Guest-host chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Immune+response%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Immune response</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nanoparticles%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nanoparticles</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Shear-thinning+hydrogel%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Shear-thinning hydrogel</a></li></ul> <a href="javascript:ShowArticleKeywords(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hydrogels%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hydrogels/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transgenes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transgenes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Allografts%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Allografts</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mesenchymal+Stem+Cells%2fcytology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mesenchymal Stem Cells/cytology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mesenchymal+Stem+Cells%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mesenchymal Stem Cells/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mesenchymal+Stem+Cells%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mesenchymal Stem Cells/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22beta-Cyclodextrins%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">beta-Cyclodextrins/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transplantation%2c+Homologous%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transplantation, Homologous</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mesenchymal+Stem+Cell+Transplantation%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mesenchymal Stem Cell Transplantation/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rheology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rheology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li></ul> <a href="javascript:ShowArticleMeSH(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(12);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow13"> <td style="min-width: 40px; text-align: center;"> 13 </td> <td> <div id="citation13" class="article-citation"> <b>Ishido M</b>, Higashi K, Mori H, Ueno M, Kurokawa K. DNA methylation profiles of transgenerational rat hyperactivity primed by silver nanoparticles: Comparison with valproate model <span class="highlight-field">rats</span> of autism. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115293. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39419183' target='_blank'>39419183</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115293' target='_blank'>10.1016/j.bbr.2024.115293</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115293','39419183', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(13);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(13);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(13);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115293' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/14/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/19/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv13" value="10.1016/j.bbr.2024.115293" /> <div style="display: none" id="articleAbstract13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">There is an increasing body of evidence suggesting that a single exposure to certain chemicals can have transgenerational effects, with the underlying mechanism believed to be epigenetic. However, it remains largely unknown whether psychiatric conditions like ADHD or autism, induced by environmental chemicals, can be inherited across generations. Pregnant rats were purchased from a commercial breeder. On the 7th day of gestation (E7), they were divided into two groups: one group was orally exposed to silver nanoparticles (AgNP; 4 mg/kg), while the control group received vehicle alone. The subsequent generation (F1) underwent spontaneous motor activity (SMA) measurements at 8-11 weeks of age. For breeding at 26 weeks of age, rats with higher SMA were selected from hyperactive litters, while untreated rats were randomly selected. This process was continued for four generations in both groups. The AgNP-primed rats at 4th generation displayed significantly higher SMA, 1.8 times greater than that of untreated rats. Intraperitoneal injection of valproic acid (150 mg/kg), an epigenetic modifier to 5-day-old rats causes adult hyperactivity (1.4-fold), suggesting that epigenetic modification contributes to rat hyperactivity. Global DNA methylation profiles in the mesencephalon were positively correlated in both groups of hyperactive rats. Furthermore, there were 7-8 common genes showing both hypermethylation and hypomethylation, which are involved in neuronal development, neuronal function, transcriptional activity, DNA binding activity, cell differentiation, ubiquitination processes, or histone modification, including Pax 6 and Mecp 2. Thus, it is most likely that rats retain hyperactivity through mesencephalic DNA methylation status across transgeneration. </div> <a href="javascript:ShowArticleAbstract(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ADHD%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ADHD</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Epigenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Epigenetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rat+hyperactivity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rat hyperactivity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Silver+nanoparticle%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Silver nanoparticle</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transgeneration%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transgeneration</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Valproic+acid%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Valproic acid</a></li></ul> <a href="javascript:ShowArticleKeywords(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Valproic+Acid%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Valproic Acid/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Metal+Nanoparticles%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Metal Nanoparticles</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA+Methylation%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA Methylation/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Silver%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Silver/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Autistic+Disorder%2fchemically+induced%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Autistic Disorder/chemically induced</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Autistic+Disorder%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Autistic Disorder/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pregnancy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pregnancy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prenatal+Exposure+Delayed+Effects%2fchemically+induced%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prenatal Exposure Delayed Effects/chemically induced</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Epigenesis%2c+Genetic%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Epigenesis, Genetic/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hyperkinesis%2fchemically+induced%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hyperkinesis/chemically induced</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Motor+Activity%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Motor Activity/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li></ul> <a href="javascript:ShowArticleMeSH(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(13);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow14"> <td style="min-width: 40px; text-align: center;"> 14 </td> <td> <div id="citation14" class="article-citation"> <b>Laux DA</b>, Azuma MC, Cain ME. Effects of repeated voluntary oral consumption of synthetic delta-9-tetrahydrocannabinol on locomotor activity and cannabinoid receptor 1 expression. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115315. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39461370' target='_blank'>39461370</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11570332' target='_blank'>PMC11570332</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115315' target='_blank'>10.1016/j.bbr.2024.115315</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115315','39461370', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(14);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(14);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(14);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(14);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115315' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/29/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv14" value="10.1016/j.bbr.2024.115315" /> <div style="display: none" id="articleAbstract14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">As cannabis legalization expands, preclinical studies continue to investigate the impact of repeated exposure to delta-9-tetrahydrocannabinol (THC), the primary psychoactive compound in the plant. With the increasing popularity of cannabis infused foods, the rise of THC in medicinal applications have also expanded. The present study addresses a critical gap in existing literature by investigating the behavioral and neurobiological effects of low-dose edible THC in a preclinical rodent model. Adult male rats were administered synthetic-THC (Dronabinol) (0.0625 mg/kg, 0.125 mg/kg, and 0.25 mg/kg) or vehicle (sesame oil) through edible cookies, 90 min prior to eight locomotor sessions. Locomotor activity significantly increased in both 0.0625 mg/kg and 0.25 mg/kg THC groups, indicating a dose-dependent relationship. Repeated 0.25 mg/kg THC administration dose-dependently reduced cannabinoid receptor 1 expression in the hippocampus. The observed neurobiological change from low dose oral THC advances our understanding of repeated cannabis use. These findings also emphasize the importance of refining rodent models for translational relevance. </div> <a href="javascript:ShowArticleAbstract(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cannabinoid+receptor+1+(CB1)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cannabinoid receptor 1 (CB1)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Delta-9-Tetrahyrocannabinol+(THC)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Delta-9-Tetrahyrocannabinol (THC)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dronabinol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dronabinol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Edibles%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Edibles</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Locomotor+activity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Locomotor activity</a></li></ul> <a href="javascript:ShowArticleKeywords(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dronabinol%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dronabinol/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dronabinol%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dronabinol/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Receptor%2c+Cannabinoid%2c+CB1%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Receptor, Cannabinoid, CB1/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Receptor%2c+Cannabinoid%2c+CB1%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Receptor, Cannabinoid, CB1/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dose-Response+Relationship%2c+Drug%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dose-Response Relationship, Drug</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Locomotion%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Locomotion/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Administration%2c+Oral%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Administration, Oral</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Motor+Activity%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Motor Activity/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cannabinoid+Receptor+Agonists%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cannabinoid Receptor Agonists/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cannabinoid+Receptor+Agonists%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cannabinoid Receptor Agonists/administration & dosage</a></li></ul> <a href="javascript:ShowArticleMeSH(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIGMS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">P20 GM113109 NIGMS NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(14);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow15"> <td style="min-width: 40px; text-align: center;"> 15 </td> <td> <div id="citation15" class="article-citation"> <b>Zilli GAL</b>, Sant'Ana BH, Bastiani CDS, Izolan LDR, Pulcinelli RR, Marques D, Leal MB, Gomez R. Differential effects of chronic and intermittent administration of taurine on alcohol binge drinking in male <span class="highlight-field">rats</span>. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115316. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39461369' target='_blank'>39461369</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115316' target='_blank'>10.1016/j.bbr.2024.115316</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115316','39461369', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(15);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(15);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(15);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115316' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/29/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv15" value="10.1016/j.bbr.2024.115316" /> <div style="display: none" id="articleAbstract15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Episodic consumption of high doses of alcohol in a short period (binge drinking - BD) among adolescents is known to be harmful to their brain development. Chronic use of taurine increases voluntary alcohol consumption and shows an anxiolytic-like effect in rats. In this study, we evaluated the differential effects of chronic and intermittent taurine administration on alcohol consumption and behavioral changes in adolescent and young adult rats subjected to the BD model. Male Wistar rats (35 days old) were divided into 4 groups for daily intraperitoneal administration of saline (SAL); taurine, 100 mg/kg (TAU); taurine on BD days and saline on intervals (TAU/SAL); and saline on BD days and taurine on intervals (SAL/TAU). They were exposed to 4 cycles of BD, with free access to alcoholic solution (20 % w/v), for 2 h, 3 days per week. At the end of the 3rd cycle, anxiety-like behaviors were assessed using the light-dark task. After euthanasia, plasma and prefrontal cortex samples were collected to measure corticosterone and BDNF levels, respectively. Chronic taurine treatment did not alter alcohol consumption in rats, whereas intermittent administration increased alcohol intake after 4 BD exposures (TAU/SAL: +19.4 % and SAL/TAU: +21.6 %). No anxiolytic-like effects were found by taurine administration, nor were there changes in serum corticosterone or BDNF levels in the frontal cortex of young adult rats. Intermittent taurine, but not chronic treatment, increased alcohol intake among rats after the second week of exposure. The translation of these results to humans is concerning since the combination of alcohol and drinks containing taurine is common among adolescent and young adult individuals. </div> <a href="javascript:ShowArticleAbstract(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adolescents%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adolescents</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Amino+acid%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Amino acid</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22BDNF%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">BDNF</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Corticosterone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Corticosterone</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ethanol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ethanol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Frontal+cortex%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Frontal cortex</a></li></ul> <a href="javascript:ShowArticleKeywords(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Taurine%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Taurine/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Taurine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Taurine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Binge+Drinking%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Binge Drinking/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Wistar%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Wistar</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Corticosterone%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Corticosterone/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prefrontal+Cortex%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prefrontal Cortex/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prefrontal+Cortex%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prefrontal Cortex/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ethanol%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ethanol/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ethanol%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ethanol/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain-Derived+Neurotrophic+Factor%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain-Derived Neurotrophic Factor/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain-Derived+Neurotrophic+Factor%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain-Derived Neurotrophic Factor/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alcohol+Drinking%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alcohol Drinking</a></li></ul> <a href="javascript:ShowArticleMeSH(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(15);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow16"> <td style="min-width: 40px; text-align: center;"> 16 </td> <td> <div id="citation16" class="article-citation"> <b>Cam Y</b>, Kocum CG, Houska TK, Konrad ER, Schweizer TA, Will MJ. Palatable feeding effects on expression and reinstatement of morphine conditioned place preference in male and female <span class="highlight-field">rats</span>. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115320. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39489431' target='_blank'>39489431</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115320' target='_blank'>10.1016/j.bbr.2024.115320</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115320','39489431', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(16);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(16);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(16);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115320' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/06/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/31/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv16" value="10.1016/j.bbr.2024.115320" /> <div style="display: none" id="articleAbstract16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">While many environmental factors are known to play a factor in the recovery and risk of relapse for individuals with opioid use disorder (OUD), the role of diet has been relatively unexplored. Individuals with OUD demonstrate unhealthy diet choices with an exaggerated craving for palatable "junk food," yet this relationship has not been well characterized. The present study begins to examine this relationship by first determining the influence of palatable food access on the expression of conditioned rewarding properties of acute morphine exposure in male and female rats. Following the establishment of morphine conditioned place preference (CPP) in all rats, morphine CPP expression was assessed following intra-accumbens (Acb) administration of the µ-opioid receptor agonist D-Ala2,NMe-Phe4,Glyol5-enkephalin (DAMGO) + 20 min access to no diet (ND) or high-fat (HF), in counter-balanced order. Next, all rats received 12 sessions of extinction training before CPP expression was first assessed following no treatment, then again following counter-balanced ND and HF treatments. The results showed that both male and female rats expressed similar levels of morphine CPP. Subsequent examination of morphine CPP expression revealed that HF treatment significantly reduced morphine CPP expression in males, but not females, compared to ND treatment. Neither HF or ND treatment produced morphine CPP reinstatement in either males or females following extinction. In summary, the impact of palatable feeding on the expression of conditioned drug seeking may be sex-specific and more sensitive prior to extinction. </div> <a href="javascript:ShowArticleAbstract(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DAMGO%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DAMGO</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hedonic+feeding%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hedonic feeding</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Morphine+conditioned+place+preference%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Morphine conditioned place preference</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nucleus+accumbens%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nucleus accumbens</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Opioid%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Opioid</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reinstatement%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reinstatement</a></li></ul> <a href="javascript:ShowArticleKeywords(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Morphine%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Morphine/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Morphine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Morphine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extinction%2c+Psychological%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extinction, Psychological/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extinction%2c+Psychological%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extinction, Psychological/physiology</a></li><li><a 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href="javascript:ShowArticleMeSH(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(16);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow17"> <td style="min-width: 40px; text-align: center;"> 17 </td> <td> <div id="citation17" class="article-citation"> <b>Lloret-Torres ME</b>, Barreto-Estrada JL. LF-DBS of the ventral striatum shortens persistence for morphine place preference and modulates BDNF expression in the hippocampus. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115300. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39490421' target='_blank'>39490421</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574767' target='_blank'>PMC11574767</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115300' target='_blank'>10.1016/j.bbr.2024.115300</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115300','39490421', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(17);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(17);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(17);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(17);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115300' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv17" value="10.1016/j.bbr.2024.115300" /> <div style="display: none" id="articleAbstract17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Deep brain stimulation (DBS) of the ventral capsule/ventral striatum (VC/VS) represents a promising therapy for treatment-refractory patients with substance-use disorders. We previously found that low-frequency (LF) DBS aimed to the VC/VS during extinction training strengthens the extinction memory for morphine seeking under a partial extinction protocol. </div><div class="abstract-label">OBJECTIVES/HYPOTHESIS</div><div class="abstract-content">In this study, animals were tested in a full extinction protocol to determine whether LF-DBS applied during extinction facilitates extinction while preventing drug reinstatement, and study the molecular mechanisms underlying the effects of LF-DBS, METHODS/RESULTS: We used a full extinction CPP paradigm combined with LF-DBS to assess behavior. Western blots for the pro-extinction molecule, brain-derived neurotrophic factor (BDNF) were then performed in corticomesolimbic regions of the brain. Lastly, to determine whether changes in BDNF expression elicited by LF-DBS were specific to the VS/NAc afferents from the hippocampus, amygdala, and medial prefrontal cortex, we performed BDNF-like immunohistochemistry, combined with the retrograde tracer cholera toxin B (CtB). </div><div class="abstract-label">RESULTS</div><div class="abstract-content">We showed a significant reduction in the number of days required to fully extinguish morphine CPP in animals exposed to LF-DBS during extinction training accompanied by a significant increase in BDNF expression in the hippocampus. However, LF-DBS applied during extinction did not prevent drug reinstatement. Lastly, no changes in BDNF/CtB double-labeled cells were found in VS/NAc projecting cells after one-day exposure to LF-DBS. </div><div class="abstract-label">CONCLUSION(S)</div><div class="abstract-content">These data suggest that LF-DBS can facilitate extinction of morphine CPP by decreasing drug seeking through potential synaptic plasticity changes in the hippocampus to strengthen extinction memories. </div> <a href="javascript:ShowArticleAbstract(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22BDNF%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">BDNF</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extinction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extinction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Low+frequency-DBS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Low frequency-DBS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Morphine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Morphine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22VS%2fNAc%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">VS/NAc</a></li></ul> <a href="javascript:ShowArticleKeywords(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain-Derived+Neurotrophic+Factor%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain-Derived Neurotrophic Factor/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Morphine%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Morphine/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Morphine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Morphine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extinction%2c+Psychological%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extinction, Psychological/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extinction%2c+Psychological%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extinction, Psychological/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ventral+Striatum%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ventral Striatum/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ventral+Striatum%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ventral Striatum/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Deep+Brain+Stimulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Deep Brain Stimulation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Drug-Seeking+Behavior%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Drug-Seeking Behavior/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Drug-Seeking+Behavior%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Drug-Seeking Behavior/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Narcotics%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Narcotics/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Narcotics%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Narcotics/administration & dosage</a></li></ul> <a href="javascript:ShowArticleMeSH(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIGMS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">P30 GM149367 NIGMS NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIGMS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R25 GM061838 NIGMS NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIDA+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SC2 DA047809 NIDA NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIMHD+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">U54 MD007600 NIMHD NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(17);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow18"> <td style="min-width: 40px; text-align: center;"> 18 </td> <td> <div id="citation18" class="article-citation"> <b>Aguilar BL</b>, Toib J, Malkova L, Forcelli PA. An unescapable looming threat paradigm for assessing anxiety-like responses in <span class="highlight-field">rats</span>. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115296. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39426528' target='_blank'>39426528</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115296' target='_blank'>10.1016/j.bbr.2024.115296</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115296','39426528', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(18);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(18);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(18);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(18);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115296' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/21/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv18" value="10.1016/j.bbr.2024.115296" /> <div style="display: none" id="articleAbstract18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Rapidly approaching visual stimuli (i.e. looming objects) are known to evoke unconditioned defense responses across species. In rodents, this threat reactivity repertoire includes freezing and fleeing behavior. Although components of the circuitry underlying unconditioned response to a looming threat have been elucidated, both a temporal characterization and drug effects on the freezing response have not yet been reported. Here, we describe a modified version of a looming threat task in which no escape route is available. In this task, we observed unconditioned freezing prior to, during, and after exposure to a looming threat stimulus. In Long Evans (LE) and Sprague-Dawley (SD) rats, we report looming stimulus-specific freezing response. We further explored the specificity and pharmacosensitivity of this response in male and female LE rats. Administration of a GABA-A receptor negative allosteric modulator (FG-7142) did not re-establish freezing in habituated animals; however, administration of a GABA-A receptor positive allosteric modulator (diazepam) in naïve LEs significantly reduced freezing during the post-looming period in a sex-dependent manner. Presentation of an unescapable looming stimulus results in freezing that extends beyond the acute threat exposure. Because freezing responses outlast the initial threat, and display only modest sensitivity to conventional anxiolytic therapy, this may represent a platform for screening agents in treatment-refractory anxiety. </div> <a href="javascript:ShowArticleAbstract(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Benzodiazepine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Benzodiazepine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Beta+carboline%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Beta carboline</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ethology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ethology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Predator%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Predator</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Unconditioned+fear%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Unconditioned fear</a></li></ul> <a href="javascript:ShowArticleKeywords(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Long-Evans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Long-Evans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diazepam%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diazepam/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fear%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fear/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fear%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fear/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anti-Anxiety+Agents%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anti-Anxiety Agents/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Freezing+Reaction%2c+Cataleptic%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Freezing Reaction, Cataleptic/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Freezing+Reaction%2c+Cataleptic%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Freezing Reaction, Cataleptic/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Photic+Stimulation%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Photic Stimulation/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbolines%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbolines</a></li></ul> <a href="javascript:ShowArticleMeSH(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">T32 NS041218 NINDS NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(18);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow19"> <td style="min-width: 40px; text-align: center;"> 19 </td> <td> <div id="citation19" class="article-citation"> <b>Mayberry HK</b>, Rinker JA, Chandler LJ. Effect of chronic alcohol exposure and single-prolonged stress on conditioned fear behavior. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115294. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39419182' target='_blank'>39419182</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115294' target='_blank'>10.1016/j.bbr.2024.115294</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115294','39419182', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(19);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(19);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(19);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115294' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/14/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/19/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv19" value="10.1016/j.bbr.2024.115294" /> <div style="display: none" id="articleAbstract19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The present study investigated the impact of chronic intermittent ethanol (CIE) exposure and single-prolonged stress (SPS) on the acquisition of fear memories in both male and female Wistar rats. Adult rats were first subjected to CIE by vapor inhalation followed by SPS. Following a subsequent 8-day incubation period, the rats underwent a Pavlovian fear conditioning procedure (tone-shock pairings) followed by cued-tone extinction training, and then testing of extinction recall memory and fear renewal memory. In control animals that had not been exposed to either CIE or SPS, female rats exhibited significantly lower levels of freezing compared to male rats during tone-shock pairings. This lower level of freezing in female rats during conditioning was associated with an increased speed of movement compared to males. Also compared to males, female rats exhibited lower levels of fear extinction, recall, and renewal. Exposure to CIE, SPS, or CIE+SPS had no effect on freezing during the cued-conditioning, extinction, or extinction recall phases of the testing procedure in either sex. In fear renewal, CIE exposure decreased freezing in male but not female rats, while SPS increased freezing in female but not male rats. CIE exposure significantly reduced freezing during the fear renewal phase. Taken together, these results provide further evidence that male and female rats adopt different avoidance strategies for threat responding. These results also revealed that prior exposure to CIE, SPS, or CIE+SPS had minimal effects on threat responding using conditioned freezing as an indicator of fear responsivity. </div> <a href="javascript:ShowArticleAbstract(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chronic+alcohol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chronic alcohol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extinction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extinction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fear+conditioning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fear conditioning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Freezing%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Freezing</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sex-differences%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sex-differences</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Single-prolonged+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Single-prolonged stress</a></li></ul> <a href="javascript:ShowArticleKeywords(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fear%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fear/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fear%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fear/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Wistar%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Wistar</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ethanol%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ethanol/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ethanol%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ethanol/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extinction%2c+Psychological%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extinction, Psychological/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extinction%2c+Psychological%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extinction, Psychological/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%2c+Psychological%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress, Psychological/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Conditioning%2c+Classical%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Conditioning, Classical/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Conditioning%2c+Classical%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Conditioning, Classical/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cues%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cues</a></li><li><a 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target="_blank">Central Nervous System Depressants/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sex+Characteristics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sex Characteristics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Freezing+Reaction%2c+Cataleptic%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Freezing Reaction, Cataleptic/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Freezing+Reaction%2c+Cataleptic%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Freezing Reaction, Cataleptic/physiology</a></li></ul> <a href="javascript:ShowArticleMeSH(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(19);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow20"> <td style="min-width: 40px; text-align: center;"> 20 </td> <td> <div id="citation20" class="article-citation"> <b>Kang Y</b>, Sheng L, Li J. HINT1 promotes neuronal apoptosis and triggers schizophrenia-like behavior in <span class="highlight-field">rats</span>. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115297. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39426527' target='_blank'>39426527</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115297' target='_blank'>10.1016/j.bbr.2024.115297</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115297','39426527', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(20);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(20);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(20);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115297' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/21/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv20" value="10.1016/j.bbr.2024.115297" /> <div style="display: none" id="articleAbstract20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">This study aims to investigate the mechanism by which Histidine triad nucleotide-binding protein 1 (HINT1) promotes hippocampal neuronal apoptosis, triggering schizophrenia (SZ)-like behavior in rats. By establishing a rat SZ-like model, we assessed learning, memory, emotional response, and cognitive function through the Morris Water Maze, auditory startle response, and open field tests. HINT1 expression in the hippocampus was analyzed via RT-PCR and Western blot. We also created a HINT1 overexpression model in hippocampal neuronal cells to analyze its effects on cell proliferation and apoptosis. This analysis was conducted using the CCK-8 assay and flow cytometry, along with the quantification of apoptosis-related proteins and neurotrophic factors. Our findings indicated that the SZ-like model rats exhibited diminished learning and memory abilities, altered emotional reactions, and impaired cognitive functions, alongside a notable increase in HINT1 mRNA and protein levels. HINT1 overexpression was observed to inhibit hippocampal neuronal cell proliferation and promote apoptosis, with an increase in the expression of pro-apoptotic proteins and a decrease in neurotrophic factors. These results suggest HINT1's role in the onset and development of SZ-like behavior through its upregulation and induction of apoptosis in hippocampal neuronal cells, underlining its potential as a therapeutic target. </div> <a href="javascript:ShowArticleAbstract(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HINT1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HINT1</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuronal+apoptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuronal apoptosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuronal+cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuronal cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Schizophrenia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Schizophrenia</a></li></ul> <a href="javascript:ShowArticleKeywords(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apoptosis%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apoptosis/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Schizophrenia%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Schizophrenia/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Schizophrenia%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Schizophrenia/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hippocampus%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hippocampus/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nerve+Tissue+Proteins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nerve Tissue Proteins/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurons%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurons/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurons%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurons/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Behavior%2c+Animal%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Behavior, Animal/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Proliferation%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Proliferation/physiology</a></li></ul> <a href="javascript:ShowArticleMeSH(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(20);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow21"> <td style="min-width: 40px; text-align: center;"> 21 </td> <td> <div id="citation21" class="article-citation"> <b>McElroy DL</b>, Howland JG. Sex differences in exploratory behavior of <span class="highlight-field">rats</span> successfully performing the object-in-place recognition memory test. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115303. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39442566' target='_blank'>39442566</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115303' target='_blank'>10.1016/j.bbr.2024.115303</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115303','39442566', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(21);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(21);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(21);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115303' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/20/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/25/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv21" value="10.1016/j.bbr.2024.115303" /> <div style="display: none" id="articleAbstract21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Male and female rodents display unique search strategies when exploring new and familiar environments. Sex differences are well-documented in the literature and may be observed in tasks that rely on spontaneous exploration (e.g., recognition memory tests). Therefore, we assessed patterns of male and female rat behavior in the object-in-place (OiP) test, a common recognition memory paradigm involving object-location associations. Twelve male and 12 female adult Long Evans rats were tested four times in the 1-h OiP test and exploratory behaviors were compared during habituation, sample, and test phases. Results revealed that females moved faster and farther than males, showed increased immobility frequency and reduced immobility duration, reduced outer zone mobility duration, and increased inner zone entrances, compared to males during habituations. During sample phases, female rats moved faster than males, displayed reduced immobility frequency in the inner zone, and demonstrated consistent distance travelled across repeated sessions; conversely, male rats moved less in later sessions and exhibited increased mobility frequency in the outer zone. Analyses comparing test phase behavior revealed females continued to move faster than males; however, no other sex differences were observed. These findings are consistent with previous literature highlighting unique sex differences in explorative behaviors during recognition testing. Sex differences in locomotion and mobility state behaviors may be more indicative of individual motivation and search strategy between the sexes and less indicative of recognition memory. </div> <a href="javascript:ShowArticleAbstract(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22exploration%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">exploration</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22locomotor+activity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">locomotor activity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22object+interaction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">object interaction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22rodent%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">rodent</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22search+strategy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">search strategy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22short+term+memory%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">short term memory</a></li></ul> <a href="javascript:ShowArticleKeywords(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Exploratory+Behavior%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Exploratory Behavior/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Recognition%2c+Psychology%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Recognition, Psychology/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Long-Evans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Long-Evans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sex+Characteristics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sex Characteristics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Behavior%2c+Animal%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Behavior, Animal/physiology</a></li></ul> <a href="javascript:ShowArticleMeSH(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(21);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow22"> <td style="min-width: 40px; text-align: center;"> 22 </td> <td> <div id="citation22" class="article-citation"> <b>Almeida-Souza TH</b>, Silva RS, Franco HS, Santos LM, Melo JEC, Oliveira E Silva AMD, Menezes ECD, Santos JRD, Teixeira-Silva F, Goes TC, Marchioro M. Involvement of the serotonergic, GABAergic and glutamatergic systems of the rostral anterior cingulate cortex in the trait and state anxiety of adult male Wistar <span class="highlight-field">rats</span>. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115298. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39433219' target='_blank'>39433219</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115298' target='_blank'>10.1016/j.bbr.2024.115298</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115298','39433219', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(22);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(22);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(22);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115298' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/23/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv22" value="10.1016/j.bbr.2024.115298" /> <div style="display: none" id="articleAbstract22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Despite significant advancements to understand of the neural circuitry involved in anxiety, the neurobiology of trait anxiety remains unclear. The rostral anterior cingulate cortex (rACC) and various pathways have been implicated in its regulation, making it a key to trait anxiety. The present study aimed to investigate the role of these neurotransmitter systems in the rACC in trait anxiety. Since trait anxiety is known to modulate state anxiety, we further investigated this relationship. Specifically, in Experiment I, we used animals with high trait anxiety; in Experiment II, we used animals with low trait anxiety; and in Experiment III, we used animals with medium trait anxiety. Before each behavioral assessment, drugs that either increased or decreased serotonergic (Fluoxetine or WAY-100635), GABAergic (Muscimol or Bicuculline), and glutamatergic (NMDA or Ketamine) neurotransmission in the rACC were administered, along with their respective controls. Additionally, in Experiment IV, all animals from the previous experiments were subjected to the Elevated Plus Maze (EPM) and Hole board (HB) test and evaluated without taking into account their trait anxiety levels. The results of the present study showed that, in Exp I, the modulation of the serotonergic, GABAergic and glutamatergic systems in the rACC decreased trait anxiety in highly anxious rats, while by submitting the animals to HB, the administration of fluoxetine increased state anxiety. In Exp II, the modulation of all systems increased trait anxiety in rats with low trait anxiety, whereas, in HB, state anxiety levels were increased with the administration of NMDA. In Exp III, only the modulation of the glutamatergic system, with NMDA, increased both trait and state anxiety levels. However, none of the evaluated neurotransmitter systems altered the state anxiety modeled in the EPM. Overall, the results of the present study provide new insights into the role of the neurotransmitter systems in the rACC in the regulation of trait anxiety and state anxiety. </div> <a href="javascript:ShowArticleAbstract(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anterior+cingulate+cortex%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anterior cingulate cortex</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Free-exploratory+paradigm%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Free-exploratory paradigm</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurotransmitters%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurotransmitters</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Trait+anxiety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Trait anxiety</a></li></ul> <a href="javascript:ShowArticleKeywords(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gyrus+Cinguli%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gyrus Cinguli/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gyrus+Cinguli%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gyrus Cinguli/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Wistar%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Wistar</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glutamic+Acid%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glutamic Acid/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fluoxetine%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fluoxetine/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22gamma-Aminobutyric+Acid%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">gamma-Aminobutyric Acid/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Serotonin%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Serotonin/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/administration & dosage</a></li></ul> <a href="javascript:ShowArticleMeSH(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(22);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow23"> <td style="min-width: 40px; text-align: center;"> 23 </td> <td> <div id="citation23" class="article-citation"> <b>Zhang Y</b>, Gui L, Yin Y, Tong X, Xia G, Wang Y, Yi J, Tian C, Liu X, Yang H. Network pharmacology integrated with pharmacological evaluation for investigating the mechanism of resveratrol in perimenopausal depression. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115304. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39447964' target='_blank'>39447964</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115304' target='_blank'>10.1016/j.bbr.2024.115304</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115304','39447964', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(23);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(23);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(23);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115304' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/26/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv23" value="10.1016/j.bbr.2024.115304" /> <div style="display: none" id="articleAbstract23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Perimenopause constitutes a pivotal transitional phase characterized by hormonal variability and heightens vulnerability to depressive episodes. This study seeks to elucidate the mechanism of resveratrol (RES) in perimenopausal depression through integrated network pharmacology, molecular docking analysis, and experimental validation. Screening yielded 83 RES-related disease targets, with IL10, CCL2, and SERPINE1 identified as core genes overexpressed in perimenopausal depression. GO analysis and KEGG pathway enrichment analysis predicted that the target genes could regulate the PI3K-Akt, FoxO, HIF-1, and IL-17 signaling pathways. Molecular docking indicated SERPINE1 as a promising RES target. Consistently, in vitro experiments showed that RES significantly attenuated the inflammatory response and apoptosis of lipopolysaccharide-stimulated CTX-TNA2 cells. RES also reduced the expression of NLRP3, caspase-1, SERPINE1 proteins and acetylation, while increasing the expression of BDNF, TrkB, SIRT1, and decreasing MAO-A proteins. In vivo experiments demonstrated that RES also significantly improved the depression behaviors, increased the levels of 5-HT1A and SIRT1, and decreased levels of MAO-A of depression rats. This study unveils RES's potential targets and mechanism in perimenopausal depression, laying groundwork for future research. </div> <a href="javascript:ShowArticleAbstract(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Key+target%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Key target</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Molecular+docking%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Molecular docking</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Network+pharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Network pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Perimenopausal+depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Perimenopausal depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Resveratrol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Resveratrol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+pathway%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal pathway</a></li></ul> <a href="javascript:ShowArticleKeywords(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Resveratrol%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Resveratrol/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Resveratrol%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Resveratrol/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Perimenopause%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Perimenopause/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Network+Pharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Network Pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Molecular+Docking+Simulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Molecular Docking Simulation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antidepressive+Agents%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antidepressive Agents/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sirtuin+1%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sirtuin 1/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sirtuin+1%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sirtuin 1/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apoptosis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apoptosis/drug effects</a></li></ul> <a href="javascript:ShowArticleMeSH(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(23);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow24"> <td style="min-width: 40px; text-align: center;"> 24 </td> <td> <div id="citation24" class="article-citation"> <b>Corbett CM</b>, Bozarth SL, West EA. Effects of sex and estrous cycle on action-outcome contingencies. <em class='incite-journal-name' onclick='ShowInCiteJournal(3378);'>Behav Brain Res</em> 2025;<b>477</b>:115317. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39490537' target='_blank'>39490537</a> DOI: <a href='https://dx.doi.org/10.1016/j.bbr.2024.115317' target='_blank'>10.1016/j.bbr.2024.115317</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.bbr.2024.115317','39490537', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(24);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(24);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(24);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(24);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.bbr.2024.115317' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3378);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/24/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv24" value="10.1016/j.bbr.2024.115317" /> <div style="display: none" id="articleAbstract24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Goal-directed and habitual-like behaviors are both necessary to efficiently and effectively navigate the environment. A dysregulation between these behaviors can lead to an overreliance on habitual-like behaviors and may contribute to symptoms experienced in some neuropsychiatric disorders such as substance use disorder. One behavioral task used to evaluate goal-directed and habitual-like behavior is an action-outcome task, contingency degradation, where an action (i.e., lever press) is degraded by decoupling the receipt of a reward from the action. However, little is known about how male and female rats and females across the estrous cycle respond during contingency degradation training and extinction testing. Here, we investigated how the variable of sex and estrous cycle influences contingency degradation training and extinction testing and the correlation between baseline anxiety-like behaviors and performance on contingency degradation extinction testing in adult male and female Long-Evans rats. We found that both males and females learned the contingency degradation task. However, during extinction testing, males respond more to the contingent lever than the non-contingent lever while females do not differ in their responses on the non-contingent and contingent levers. Lower baseline anxiety-like behavior predicted better performance on the contingency degradation test in males, but not females. Next, when we examined performance during extinction testing in females based on their estrous cycle stage on test day, we found that females in the proestrus and estrus stages of the estrous cycle do not differ in their responses on the non-contingent and contingent levers, while females in the metestrus and diestrus stages of the estrous cycle respond more on the contingent lever than the non-contingent lever on the extinction test day, similar to male rats. Our findings indicate that the estrous cycle influences how female rats respond during contingency degradation extinction testing that is dependent on their estrous cycle stage. </div> <a href="javascript:ShowArticleAbstract(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Action-outcome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Action-outcome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Contingency+degradation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Contingency degradation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Estrous+cycle%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Estrous cycle</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sex%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sex</a></li></ul> <a href="javascript:ShowArticleKeywords(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Estrous+Cycle%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Estrous Cycle/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Long-Evans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Long-Evans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extinction%2c+Psychological%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extinction, Psychological/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Conditioning%2c+Operant%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Conditioning, Operant/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reward%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reward</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sex+Characteristics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sex Characteristics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Behavior%2c+Animal%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Behavior, Animal/physiology</a></li></ul> <a href="javascript:ShowArticleMeSH(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIDA+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R00 DA042934 NIDA NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(24);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow25"> <td style="min-width: 40px; text-align: center;"> 25 </td> <td> <div id="citation25" class="article-citation"> <b>Jin J</b>, Wang D, Qian H, Ruan C, Yang Y, Li D, Wang G, Zhu X, Hu Y, Lei P. Precision pore structure optimization of additive manufacturing porous tantalum scaffolds for bone regeneration: A proof-of-concept study. <em class='incite-journal-name' onclick='ShowInCiteJournal(3556);'>Biomaterials</em> 2025;<b>313</b>:122756. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39182327' target='_blank'>39182327</a> DOI: <a href='https://dx.doi.org/10.1016/j.biomaterials.2024.122756' target='_blank'>10.1016/j.biomaterials.2024.122756</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.biomaterials.2024.122756','39182327', 'Rats')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(25);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(25);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(25);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.biomaterials.2024.122756' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3556);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/27/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv25" value="10.1016/j.biomaterials.2024.122756" /> <div style="display: none" id="articleAbstract25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Currently, the treatment of bone defects in arthroplasty is a challenge in clinical practice. Nonetheless, commercially available orthopaedic scaffolds have shown limited therapeutic effects for large bone defects, especially for massiveand irregular defects. Additively manufactured porous tantalum, in particular, has emerged as a promising material for such scaffolds and is widely used in orthopaedics for its exceptional biocompatibility, osteoinduction, and mechanical properties. Porous tantalum has also exhibited unique advantages in personalised rapid manufacturing, which allows for the creation of customised scaffolds with complex geometric shapes for clinical applications at a low cost and high efficiency. However, studies on the effect of the pore structure of additively manufactured porous tantalum on bone regeneration have been rare. In this study, our group designed and fabricated a batch of precision porous tantalum scaffolds via laser powder bed fusion (LPBF) with pore sizes of 250 μm (Ta 250), 450 μm (Ta 450), 650 μm (Ta 650), and 850 μm (Ta 850). We then performed a series of in vitro experiments and observed that all four groups showed good biocompatibility. In particular, Ta 450 demonstrated the best osteogenic performance. Afterwards, our team used a rat bone defect model to determine the in vivo osteogenic effects. Based on micro-computed tomography and histology, we identified that Ta 450 exhibited the best bone ingrowth performance. Subsequently, sheep femur and hip defect models were used to further confirm the osteogenic effects of Ta 450 scaffolds. Finally, we verified the aforementioned in vitro and in vivo results via clinical application (seven patients waiting for revision total hip arthroplasty) of the Ta 450 scaffold. The clinical results confirmed that Ta 450 had satisfactory clinical outcomes up to the 12-month follow-up. In summary, our findings indicate that 450 μm is the suitable pore size for porous tantalum scaffolds. This study may provide a new therapeutic strategy for the treatment of massive, irreparable, and protracted bone defects in arthroplasty. </div> <a href="javascript:ShowArticleAbstract(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bone+defect%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bone defect</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Clinical+translation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Clinical translation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osteogenesis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osteogenesis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pore+size%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pore size</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Porous+tantalum%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Porous tantalum</a></li></ul> <a href="javascript:ShowArticleKeywords(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tantalum%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tantalum/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bone+Regeneration%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bone Regeneration/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Porosity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Porosity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tissue+Scaffolds%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tissue Scaffolds/chemistry</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osteogenesis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osteogenesis/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Proof+of+Concept+Study%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Proof of Concept Study</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Biocompatible+Materials%2fchemistry%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Biocompatible Materials/chemistry</a></li><li><a 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class="search-pager-container"> <div class="dxpLite_MetropolisBlue" id="RootHolder_SearchResultPager" style="margin-top: 20px; margin-bottom: 20px;"> <b class="dxp-lead dxp-button dxp-bi dxp-disabledButton"><img class="dxWeb_pPrevDisabled_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Prev" /></b><b class="dxp-summary" style="margin-left:0px;">Page 1 of 4000 </b><b class="dxp-num dxp-current page-number" style="margin-left:0px;">1</b><a class="dxp-num page-number" href="/Search?page=2&sort=pdate&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" style="margin-left:0px;">2</a><a class="dxp-num page-number" href="/Search?page=3&sort=pdate&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" style="margin-left:0px;">3</a><a class="dxp-num page-number" 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onclick="ASPx.PGNav(event);" href="/Search?page=2&sort=pdate&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" style="margin-left:0px;"><img class="dxWeb_pNext_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Next" /></a> </div><b class="dx-clear"></b><script id="dxss_1642908154" type="text/javascript">  </script> </div> </div> <div class="cl"></div> </div> </div> </div> <table class="dxlpLoadingPanel_MetropolisBlue dxlpControl_MetropolisBlue" id="RootHolder_LeftLoadingPanel" style="position:absolute;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="text-align:Center;vertical-align:Top;"><span id="RootHolder_LeftLoadingPanel_TL">Loading…</span></td> </tr> </table><div id="RootHolder_LeftLoadingPanel_LD" class="dxlpLoadingDiv_MetropolisBlue dxlpControl_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1950550554" type="text/javascript">  </script> <div id="RootHolder_articleCitationPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:450px;width:600px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam"></span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content">    </div> </div> </div> </div><div id="RootHolder_articleCitationPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_articleCitationPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleCitationPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleCitationPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1115091042" type="text/javascript">  </script> <div id="RootHolder_chartPopupControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:1000px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_chartPopupControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam"></span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_chartPopupControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_chartPopupControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_chartPopupControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_chartPopupControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_420552910" type="text/javascript">  </script> <div id="RootHolder_pcImportArticlesControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:50px;width:50px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcImportArticlesControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Import Articles</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="RootHolder_pcImportArticlesControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcImportArticlesControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcImportArticlesControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcImportArticlesControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_365297802" type="text/javascript">  </script> <div id="RootHolder_pcEditArticleControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcEditArticleControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Edit My Journal Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_pcEditArticleControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcEditArticleControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcEditArticleControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcEditArticleControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_298765222" type="text/javascript">  </script> <div id="RootHolder_userIndexComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:400px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Article Influence Index</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle2">Article Influence Index</span></b> </p> <p> Total Citations in Crossref ÷ Total Articles = <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle3">Article Influence Index</span><sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="RootHolder_userIndexComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_userIndexComputePopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_userIndexComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1286575841" type="text/javascript">  </script> <div id="RootHolder_articleExportPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:280px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow" style="font-size:11pt;"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_articleExportPopup_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Export Articles to File</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="dxtcLite_MetropolisBlue dxtcSys dxtc-init dxtc-top dxtc-pc" id="RootHolder_articleExportPopup_ExportFilePageControl" style="width:100%;"> <ul class="dxtc-strip dxtc-row dxtc-stripContainer"> <li class="dxtc-leftIndent"> </li><li class="dxtc-tab dxtc-lead" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-activeTab dxtc-lead"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-spacer"> </li><li class="dxtc-tab dxtc-last"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-activeTab dxtc-last" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-rightIndent"> </li> </ul><div class="dxtc-content"> <div> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_SearchTermText1">Rats (1284487 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:5px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_1662381219" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailEndIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_616434442" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_1167331127" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_54524200" type="text/javascript">  </script><script id="dxss_1678130197" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" style="font-weight:bold;">JCR Year:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" type="hidden" value="2023" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" value="2023" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2023</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2022</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2021</td> </tr> </table> </div></td> </tr> </table><script id="dxss_830317689" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_167955898" type="text/javascript">  </script><script id="dxss_2013408041" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1062639383" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_104403608" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1973673553" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_6" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLTSys dxflItemSys dxflCheckBoxWithTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" style="font-weight:bold;">Record Content:</label></td> </tr><tr> <td class="dxflNestedControlCell_MetropolisBlue"> <table> <tr> <td style="vertical-align: middle; padding: 5px;"> <table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields" style="color:#BD4100;"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$cbSelectAllFields" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label>Select All Fields</label></td> </tr> </table><script id="dxss_1176833720" type="text/javascript">  </script> </td> </tr> <tr> <td style="padding: 5px;"> <table class="dxeCheckBoxList_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields" style="width:100%;border-collapse:separate;"> <tr> <td class="dxe"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields" /><table style="width:100%;"> <tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB0" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Author(s)</label></td> </tr> </table><script id="dxss_771536870" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB1" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Title</label></td> </tr> </table><script id="dxss_1086331335" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB2" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Keywords</label></td> </tr> </table><script id="dxss_1308541020" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB3" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">MESH Headings</label></td> </tr> </table><script id="dxss_896786043" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB4" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Journal Title</label></td> </tr> </table><script id="dxss_450242410" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB5" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Year</label></td> </tr> </table><script id="dxss_765036875" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB6" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Type</label></td> </tr> </table><script id="dxss_1629835480" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB7" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Language</label></td> </tr> </table><script id="dxss_1218080503" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB8" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Published Date</label></td> </tr> </table><script id="dxss_1428514578" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB9" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author</label></td> </tr> </table><script id="dxss_1113720113" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB10" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author’s Affiliations</label></td> </tr> </table><script id="dxss_310841941" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB11" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author</label></td> </tr> </table><script id="dxss_1301541094" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB12" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author’s Affiliations</label></td> </tr> </table><script id="dxss_675718561" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB13" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Email</label></td> </tr> </table><script id="dxss_2006865700" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB14" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">All Authors's Affiliations</label></td> </tr> </table><script id="dxss_1204905793" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB15" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Grant</label></td> </tr> </table><script id="dxss_407477242" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB16" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">ISSN</label></td> </tr> </table><script id="dxss_218345291" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB17" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Publisher</label></td> </tr> </table><script id="dxss_1394037744" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB18" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexing / Abstracting</label></td> </tr> </table><script id="dxss_319681069" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB19" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Factor</label></td> </tr> </table><script id="dxss_1292701966" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB20" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">JCR Quartile</label></td> </tr> </table><script id="dxss_1844280938" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB21" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Index Per Article</label></td> </tr> </table><script id="dxss_838303323" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB22" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Category</label></td> </tr> </table><script id="dxss_1464125856" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB23" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Times Cited in RCA</label></td> </tr> </table><script id="dxss_148257179" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB24" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Peer-Reviewed Journal</label></td> </tr> </table><script id="dxss_950217086" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB25" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Open Access</label></td> </tr> </table><script id="dxss_1732367175" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB26" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">DOI</label></td> </tr> </table><script id="dxss_1936777588" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB27" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">PMID</label></td> </tr> </table><script id="dxss_745806673" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB28" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Citation</label></td> </tr> </table><script id="dxss_1835441810" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB29" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexed in RCA</label></td> </tr> </table><script id="dxss_847142451" type="text/javascript">  </script></td><td></td><td></td> </tr> </table></td> </tr> </table><script id="dxss_1169734383" type="text/javascript">  </script> </td> </tr> </table> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_7" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportedDetailFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_1198171345" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_1960175520" type="text/javascript">  </script> </div> </div><div style="display:none;"> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_SearchTermText2">Rats (1284487 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:10px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_814491935" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportEndSIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_1331245653" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:10px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_2046065225" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_1926633208" type="text/javascript">  </script><script id="dxss_228619664" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:20px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" type="hidden" value="1" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" value="Excel" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1509722775" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_960798088" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_835950349" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportedFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_308093146" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_424125632" type="text/javascript">  </script> </div> </div> </div> </div><b class="dx-clear"></b><table id="RootHolder_articleExportPopup_ExportFilePageControl_LP" class="dxtcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_TL">Loading…</span></td> </tr> </table><script id="dxss_2124675053" type="text/javascript">  </script> </div> </div><div class="dxpc-footer"> <div class="popup-footer-button-container"> <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles_I" class="dxb-hb" value="Export" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnExportArticles" /><span class="dx-vam">Export</span> </div> </div><script id="dxss_77486387" type="text/javascript">  </script>    <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnCancel" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnCancel_I" class="dxb-hb" value="Cancel" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnCancel" /><span class="dx-vam">Cancel</span> </div> </div><script id="dxss_2118985763" type="text/javascript">  </script> </div> </div> </div> </div><div id="RootHolder_articleExportPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_articleExportPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="font-size:11pt;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="font-size:11pt;padding-left:0px;"><span id="RootHolder_articleExportPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_578446409" type="text/javascript">  </script> </div> <div class="bottom-part cl"> © 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA </div> <div class="scroll"> <a href="#top" target="_self"> <img src="/Contents/Images/backtop3.png" /> </a> </div> <div id="categorySelectorPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Select the Category</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="categorySelectorPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="categorySelectorPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="categorySelectorPopup_TL">Loading…</span></td> </tr> </table><div id="categorySelectorPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_166253781" type="text/javascript">  </script> <div id="pcLoginPopUp_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:700px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="pcLoginPopUp_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="pcLoginPopUp_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="pcLoginPopUp_TL">Loading…</span></td> </tr> </table><div id="pcLoginPopUp_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_430910140" type="text/javascript">  </script> <div id="aiComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:300px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Impact Index Per Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for Impact Index Per Article</b> </p> <p> Times Cited ÷ Number of Years = Impact Index Per Article<sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="aiComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="aiComputePopup_TL">Loading…</span></td> </tr> </table><div id="aiComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_698179129" type="text/javascript">  </script> <script type="text/javascript"> //<![CDATA[ var callBackFrameUrl='/WebResource.axd?d=beToSAE3vdsL1QUQUxjWdX-3aFLejnBliGvqSCZYULGFdxZmRlcJcqs71AKVNTQEXljNmd0slFkUZ_AFaCke4Q2&t=638628207619783110'; WebForm_InitCallback();//]]> </script> </form> </body> </html>