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KEGG COMPOUND: C00051
<!doctype html> <html><head> <title>KEGG COMPOUND: C00051</title> <link type="text/css" rel="stylesheet" href="/css/gn2.css?1732774964"> <link type="text/css" rel="stylesheet" href="/css/bget.css?1732774964"> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link type="text/css" rel="stylesheet" href="/css/bgetm.css?1732774964" media="only screen and (max-width: 768px)"> <style>.kcfd{display:none;}</style> <script> <!-- var getElementsByClassName = document.getElementsByClassName ? function (cl){ return document.getElementsByClassName(cl); } : function (cl){ var elms = []; var objs = document.getElementsByTagName('*'); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(obj.className == cl){ elms.push(obj); } } return elms; }; function toggleField(clk,cl,show,hide){ var objs = getElementsByClassName(cl); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(!obj.style.display||obj.style.display == 'none'){ obj.style.display = 'block'; clk.innerHTML = ' « '+hide; 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form.setAttribute(key,params[key]); } else{ var obj = document.createElement('input'); obj.setAttribute('type','hidden'); obj.setAttribute('name',key); obj.setAttribute('value',params[key]); form.appendChild(obj); } } form.submit(); } window.onload=function(){window.focus();init();}; //---> </script> </head> <body> <div> <table border=0 cellpadding=0 cellspacing=0><tr><td> <table border=0 cellpadding=0 cellspacing=0 width="650"><tr><td width=70><a href="/kegg/kegg2.html"><img align="middle" alt="KEGG" border=0 src="/Fig/bget/kegg2.gif"></a></td><td> </td><td><a name="compound:C00051"></a><font class="title2">COMPOUND: C00051</font></td><td class="tar vbot"><button class="btn" onclick="javascript:void(window.open('/kegg/document/help_bget_compound.html','KEGG_Help','toolbar=no,location=no,directories=no,width=720,height=640,resizable=yes,scrollbars=yes'));return false;">Help</button></td></tr></table><form method="post" action="/entry/" enctype="application/x-www-form-urlencoded" id="form1" name="form1"></form><table class="w1" width="650"> <tr> <td class="fr2 w1"> <table width="650" class="w2"> <tr><th class="th20 deft tal vmid"><span class="nowrap">Entry</span></th> <td class="td20 defd"><table class="w1" width="100%"><tr><td class="tal pd0"><code><span class="nowrap">C00051 Compound <br> </span></code></td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Name</span></th> <td class="td21 defd"><div class="cel"><div class="cel">Glutathione;<br> 5-L-Glutamyl-L-cysteinylglycine;<br> N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine;<br> gamma-L-Glutamyl-L-cysteinyl-glycine;<br> GSH;<br> Reduced glutathione<br> </div></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Formula</span></th> <td class="td20 defd"><div class="cel">C10H17N3O6S<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Exact mass</span></th> <td class="td21 defd"><div class="cel">307.0838<br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Mol weight</span></th> <td class="td20 defd"><div class="cel">307.33<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Structure</span></th> <td class="td21 defd"><a href="/Fig/compound/C00051.gif"><img name="img0" src="/Fig/compound/C00051.gif" style="max-width:600px" border=0></a><br> <button class="btn" onclick="location.href='/entry/-f+m+C00051';return false;">Mol file</button><button class="btn" onclick="location.href='/entry/-f+k+C00051';return false;">KCF file</button><button class="btn" onclick="location.href='https://www.genome.jp/tools-bin/strsearch_view?ENTRY=C00051&PROGRAM=simcomp&DATABASE=compound';return false;">DB search</button></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Remark</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">Same as: </span></td><td><a href="/entry/D00014">D00014</a></td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Reaction</span></th> <td class="td21 defd"><div class="cel"><a href="/entry/R00094">R00094</a> <a href="/entry/R00115">R00115</a> <a href="/entry/R00120">R00120</a> <a href="/entry/R00274">R00274</a> <a href="/entry/R00494">R00494</a> <a href="/entry/R00497">R00497</a> <a href="/entry/R00499">R00499</a> <a href="/entry/R00527">R00527</a> <br> <a href="/entry/R00547">R00547</a> <a href="/entry/R00900">R00900</a> <a href="/entry/R01108">R01108</a> <a href="/entry/R01109">R01109</a> <a href="/entry/R01110">R01110</a> <a href="/entry/R01111">R01111</a> <a href="/entry/R01113">R01113</a> <a href="/entry/R01262">R01262</a> <br> <a href="/entry/R01292">R01292</a> <a href="/entry/R01736">R01736</a> <a href="/entry/R01875">R01875</a> <a href="/entry/R01917">R01917</a> <a href="/entry/R01918">R01918</a> <a href="/entry/R02530">R02530</a> <a href="/entry/R02824">R02824</a> <a href="/entry/R03059">R03059</a> <br> <a href="/entry/R03082">R03082</a> <a href="/entry/R03167">R03167</a> <a href="/entry/R03522">R03522</a> <a href="/entry/R03822">R03822</a> <a href="/entry/R03915">R03915</a> <a href="/entry/R03956">R03956</a> <a href="/entry/R03984">R03984</a> <a href="/entry/R04039">R04039</a> <br> <a href="/entry/R04090">R04090</a> <a href="/entry/R04860">R04860</a> <a href="/entry/R05267">R05267</a> <a href="/entry/R05269">R05269</a> <a href="/entry/R05402">R05402</a> <a href="/entry/R05403">R05403</a> <a href="/entry/R05714">R05714</a> <a href="/entry/R05717">R05717</a> <br> <a href="/entry/R05748">R05748</a> <a href="/entry/R06982">R06982</a> <a href="/entry/R07002">R07002</a> <a href="/entry/R07003">R07003</a> <a href="/entry/R07004">R07004</a> <a href="/entry/R07023">R07023</a> <a href="/entry/R07024">R07024</a> <a href="/entry/R07025">R07025</a> <br> <a href="/entry/R07026">R07026</a> <a href="/entry/R07034">R07034</a> <a href="/entry/R07035">R07035</a> <a href="/entry/R07069">R07069</a> <a href="/entry/R07070">R07070</a> <a href="/entry/R07083">R07083</a> <a href="/entry/R07084">R07084</a> <a href="/entry/R07091">R07091</a> <br> <a href="/entry/R07092">R07092</a> <a href="/entry/R07093">R07093</a> <a href="/entry/R07094">R07094</a> <a href="/entry/R07100">R07100</a> <a href="/entry/R07113">R07113</a> <a href="/entry/R07116">R07116</a> <a href="/entry/R07124">R07124</a> <a href="/entry/R08280">R08280</a> <br> <a href="/entry/R08350">R08350</a> <a href="/entry/R08351">R08351</a> <a href="/entry/R08352">R08352</a> <a href="/entry/R08353">R08353</a> <a href="/entry/R08354">R08354</a> <a href="/entry/R08355">R08355</a> <a href="/entry/R08511">R08511</a> <a href="/entry/R08512">R08512</a> <br> <a href="/entry/R08678">R08678</a> <a href="/entry/R09338">R09338</a> <a href="/entry/R09367">R09367</a> <a href="/entry/R09368">R09368</a> <a href="/entry/R09409">R09409</a> <a href="/entry/R11411">R11411</a> <a href="/entry/R11650">R11650</a> <a href="/entry/R11652">R11652</a> <br> <style>.r1{display:none;}</style><div class="r1"><a href="/entry/R11659">R11659</a> <a href="/entry/R11734">R11734</a> <a href="/entry/R11736">R11736</a> <a href="/entry/R11737">R11737</a> <a href="/entry/R11739">R11739</a> <a href="/entry/R11861">R11861</a> <a href="/entry/R11905">R11905</a> <a href="/entry/R11929">R11929</a> <br> <a href="/entry/R11947">R11947</a> <a href="/entry/R12578">R12578</a> <a href="/entry/R12917">R12917</a> <a href="/entry/R12918">R12918</a> <a href="/entry/R12919">R12919</a> <a href="/entry/R12946">R12946</a> <a href="/entry/R13043">R13043</a><br> </div><a href="javascript:void(0)" onclick="javascript:toggleField(this,"r1","show all","hide")"> » show all</a><br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Pathway</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map00270+C00051">map00270</a> </span></td><td>Cysteine and methionine metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map00480+C00051">map00480</a> </span></td><td>Glutathione metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01100+C00051">map01100</a> </span></td><td>Metabolic pathways</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01240+C00051">map01240</a> </span></td><td>Biosynthesis of cofactors</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map02010+C00051">map02010</a> </span></td><td>ABC transporters</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04216+C00051">map04216</a> </span></td><td>Ferroptosis</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04918+C00051">map04918</a> </span></td><td>Thyroid hormone synthesis</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04976+C00051">map04976</a> </span></td><td>Bile secretion</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05208+C00051">map05208</a> </span></td><td>Chemical carcinogenesis - reactive oxygen species</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05415+C00051">map05415</a> </span></td><td>Diabetic cardiomyopathy</td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Module</span></th> <td class="td21 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/module/M00118+C00051">M00118</a> </span></td><td>Glutathione biosynthesis, glutamate => glutathione</td></tr></table></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Network</span></th> <td class="td20 defd"><div class="cel"><a href="/network/nt06026+C00051">nt06026</a> Glutathione biosynthesis<br><a href="/network/nt06525+C00051">nt06525</a> Ferroptosis</div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Enzyme</span></th> <td class="td21 defd"><div class="cel"><a href="/entry/1.5.4.1">1.5.4.1</a> <a href="/entry/1.8.1.7">1.8.1.7</a> <a href="/entry/1.8.1.9">1.8.1.9</a> <a href="/entry/1.8.1.10">1.8.1.10</a> <br> <a href="/entry/1.8.3.3">1.8.3.3</a> <a href="/entry/1.8.4.1">1.8.4.1</a> <a href="/entry/1.8.4.2">1.8.4.2</a> <a href="/entry/1.8.4.3">1.8.4.3</a> <br> <a href="/entry/1.8.4.4">1.8.4.4</a> <a href="/entry/1.8.4.7">1.8.4.7</a> <a href="/entry/1.8.4.9">1.8.4.9</a> <a href="/entry/1.8.5.1">1.8.5.1</a> <br> <a href="/entry/1.8.5.7">1.8.5.7</a> <a href="/entry/1.8.5.8">1.8.5.8</a> <a href="/entry/1.11.1.9">1.11.1.9</a> <a href="/entry/1.11.1.12">1.11.1.12</a> <br> <a href="/entry/1.11.1.27">1.11.1.27</a> <a href="/entry/1.13.11.18">1.13.11.18</a> <a href="/entry/1.14.14.43">1.14.14.43</a> <a href="/entry/1.14.14.45">1.14.14.45</a> <br> <a href="/entry/1.20.4.2">1.20.4.2</a> <a href="/entry/1.21.4.5">1.21.4.5</a> <a href="/entry/2.1.1.137">2.1.1.137</a> <a href="/entry/2.3.2.2">2.3.2.2</a> <br> <a href="/entry/2.3.2.15">2.3.2.15</a> <a href="/entry/2.5.1.18">2.5.1.18</a> 2.5.1.- <a href="/entry/2.8.1.3">2.8.1.3</a> <br> <a href="/entry/2.8.4.6">2.8.4.6</a> <a href="/entry/3.1.2.6">3.1.2.6</a> <a href="/entry/3.1.2.7">3.1.2.7</a> <a href="/entry/3.1.2.12">3.1.2.12</a> <br> <a href="/entry/3.1.2.13">3.1.2.13</a> <a href="/entry/3.4.19.13">3.4.19.13</a> <a href="/entry/3.5.1.78">3.5.1.78</a> 3.5.1.- <br> <a href="/entry/4.3.2.7">4.3.2.7</a> <a href="/entry/4.4.1.5">4.4.1.5</a> <a href="/entry/4.4.1.20">4.4.1.20</a> <a href="/entry/4.4.1.22">4.4.1.22</a> <br> <style>.e1{display:none;}</style><div class="e1"><a href="/entry/4.4.1.34">4.4.1.34</a> <a href="/entry/6.3.1.8">6.3.1.8</a> <a href="/entry/6.3.1.9">6.3.1.9</a> <a href="/entry/6.3.2.3">6.3.2.3</a><br> </div><a href="javascript:void(0)" onclick="javascript:toggleField(this,"e1","show all","hide")"> » show all</a><br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Brite</span></th> <td class="td20 defd"><div class="cel"><span class="nowrap">Compounds with biological roles [BR:<a href="/brite/br08001+C00051">br08001</a>]<br> Vitamins and cofactors<br> Cofactors<br> Coenzymes<br> C00051 Glutathione<br> Anatomical Therapeutic Chemical (ATC) classification [BR:<a href="/brite/br08303+D00014">br08303</a>]<br> V VARIOUS<br> V03 ALL OTHER THERAPEUTIC PRODUCTS<br> V03A ALL OTHER THERAPEUTIC PRODUCTS<br> V03AB Antidotes<br> V03AB32 Glutathione<br> D00014 Glutathione (JP18) <JP><br> Therapeutic category of drugs in Japan [BR:<a href="/brite/br08301+D00014">br08301</a>]<br> 3 Agents affecting metabolism<br> 39 Other agents affecting metabolism<br> 392 Antidotes<br> 3922 Glutathiones<br> D00014 Glutathione (JP18)<br> Animal drugs in Japan [BR:<a href="/brite/br08331+C00051">br08331</a>]<br> 96 Agents affecting metabolism<br> 967 Agents for liver disease and antidotes<br> 9676 Other amino acid and preparations<br> C00051 Glutathione<br> Drugs listed in the Japanese Pharmacopoeia [BR:<a href="/brite/br08311+D00014">br08311</a>]<br> Chemicals<br> D00014 Glutathione<br> </span></div><button class="btn" onclick="location.href='/kegg-bin/search_brite?option=-a&search_string=C00051';return false;">BRITE hierarchy</button></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Other DBs</span></th> <td class="td21 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">CAS: </span></td><td>70-18-8</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">PubChem: </span></td><td><a href="https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=3353">3353</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">ChEBI: </span></td><td><a href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16856">16856</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">KNApSAcK: </span></td><td><a href="http://kanaya.naist.jp/knapsack_jsp/information.jsp?sname=C_ID&word=C00001518">C00001518</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">PDB-CCD: </span></td><td><a href="https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/GSH">GSH</a>[<a href="https://pdbj.org/mine/summary/GSH">PDBj</a>] <a href="https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/VDW">VDW</a>[<a href="https://pdbj.org/mine/summary/VDW">PDBj</a>] </td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">NIKKAJI: </span></td><td><a href="https://jglobal.jst.go.jp/en/redirect?Nikkaji_No=J10.686K">J10.686K</a></td></tr></table></td></tr> <tr><th class="th20 deft tal vmid"><span class="nowrap">LinkDB</span></th> <td class="td20 defd"><button class="btn" onclick="location.href='https://www.genome.jp/dbget-bin/get_linkdb?compound+C00051';return false;">All DBs</button></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">KCF data</span></th> <td class="td21 defd"><button class="btn" id="kcfb1">Show</button><div class="kcfd" id="kcfd1"><br>ATOM 20<br> 1 O6a O 24.0100 -16.3100<br> 2 C6a C 25.2000 -15.6100<br> 3 C1c C 26.4600 -16.3100<br> 4 C1b C 27.6500 -15.6100<br> 5 C1b C 28.8400 -16.3100<br> 6 C5a C 30.1000 -15.6100<br> 7 N1b N 31.2900 -16.3100<br> 8 C1c C 32.4800 -15.6100<br> 9 C5a C 33.7400 -16.3100<br> 10 N1b N 34.9300 -15.6100<br> 11 C1b C 36.1200 -16.3100<br> 12 C6a C 37.3800 -15.6100<br> 13 O6a O 38.5700 -16.3100<br> 14 O6a O 25.2000 -14.2100<br> 15 N1a N 26.4600 -17.7100<br> 16 O5a O 30.1000 -14.2100<br> 17 C1b C 32.4800 -14.2100<br> 18 S1a S 33.6700 -13.5100<br> 19 O5a O 33.7400 -17.7100<br> 20 O6a O 37.3800 -14.2100<br> BOND 19<br> 1 1 2 1<br> 2 2 3 1<br> 3 3 4 1<br> 4 4 5 1<br> 5 5 6 1<br> 6 6 7 1<br> 7 7 8 1<br> 8 8 9 1<br> 9 9 10 1<br> 10 10 11 1<br> 11 11 12 1<br> 12 12 13 1<br> 13 2 14 2<br> 14 3 15 1 #Down<br> 15 6 16 2<br> 16 8 17 1 #Up<br> 17 17 18 1<br> 18 9 19 2<br> 19 12 20 2<br> </div></td></tr> </table></td></tr></table> <br><span style="font-size:12px"><a href="/entry/cpd_ja:C00051">» Japanese version</a></span><br><br></td></tr></table> <a href="/dbget/">DBGET</a> integrated database retrieval system</div> </body> </html>