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class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><style data-mw-deduplicate="TemplateStyles:r1238436933">.mw-parser-output .ombox{margin:4px 0;border-collapse:collapse;border:1px solid #a2a9b1;background-color:var(--background-color-neutral-subtle,#f8f9fa);box-sizing:border-box;color:var(--color-base,#202122)}.mw-parser-output .ombox.mbox-small{font-size:88%;line-height:1.25em}.mw-parser-output .ombox-speedy{border:2px solid #b32424;background-color:#fee7e6}.mw-parser-output .ombox-delete{border:2px solid #b32424}.mw-parser-output .ombox-content{border:1px solid #f28500}.mw-parser-output .ombox-style{border:1px solid #fc3}.mw-parser-output .ombox-move{border:1px solid #9932cc}.mw-parser-output .ombox-protection{border:2px solid #a2a9b1}.mw-parser-output .ombox .mbox-text{border:none;padding:0.25em 0.9em;width:100%}.mw-parser-output .ombox .mbox-image{border:none;padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .ombox .mbox-imageright{border:none;padding:2px 0.9em 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solid;margin-top:5px;padding-top:5px}.mw-parser-output .afc-submission-pending{background-color:#f3eba3}.mw-parser-output .afc-submission-declined,.mw-parser-output .afc-submission-rejected{background-color:#fee}.mw-parser-output .afc-submission-reviewing{background-color:#b1dae8}.mw-parser-output .afc-submission-declined-comment{background-color:var(--background-color-neutral-subtle,#f8f9fa);border:1px solid #999;margin:0.5em;padding:1em}@media screen{html.skin-theme-clientpref-night .mw-parser-output .afc-submission-pending{background-color:#381C03}html.skin-theme-clientpref-night .mw-parser-output .afc-submission-declined,html.skin-theme-clientpref-night .mw-parser-output .afc-submission-rejected{background-color:#300}html.skin-theme-clientpref-night .mw-parser-output .afc-submission-reviewing{background-color:#0d1a27}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .afc-submission-pending{background-color:#381C03}html.skin-theme-clientpref-os .mw-parser-output .afc-submission-declined,html.skin-theme-clientpref-os .mw-parser-output .afc-submission-rejected{background-color:#300}html.skin-theme-clientpref-os .mw-parser-output .afc-submission-reviewing{background-color:#0d1a27}}</style><table class="plainlinks ombox ombox-notice afc-submission-declined" role="presentation"><tbody><tr><td class="mbox-empty-cell"></td><td class="mbox-text"><span class="afc-submission-header">Submission declined on 24 July 2024 by <span class="plainlinks"><a class="external text" href="https://en.wikipedia.org/wiki/User:Mgp28">Mgp28</a></span> (<a href="/wiki/User_talk:Mgp28" title="User talk:Mgp28">talk</a>).</span><div class="afc-submission-declined-comment">The proposed article does not have sufficient content to require an article of its own, but it could be merged into the existing article at <a href="/wiki/Hibernation_factor" title="Hibernation factor">Hibernation factor</a>. Since anyone can edit Wikipedia, you are welcome to add that information yourself. Thank you.</div><div><ul><li>If you would like to continue working on the submission, click on the "Edit" tab at the top of the window.</li><li>If you have not resolved the issues listed above, your draft will be declined again and potentially deleted.</li><li>If you need extra help, please <span class="plainlinks"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Wikipedia:WikiProject_Articles_for_creation/Help_desk/New_question&withJS=MediaWiki:AFCHD-wizard.js&page=Draft:Balon_(protein)"><b>ask us a question</b></a></span> at the AfC Help Desk or get <b><a href="/wiki/Wikipedia:IRC_help_disclaimer" title="Wikipedia:IRC help disclaimer">live help</a></b> from experienced editors.</li><li>Please do not remove reviewer comments or this notice until the submission is accepted.</li></ul></div> <hr /> <style data-mw-deduplicate="TemplateStyles:r1214851843">.mw-parser-output .hidden-begin{box-sizing:border-box;width:100%;padding:5px;border:none;font-size:95%}.mw-parser-output .hidden-title{font-weight:bold;line-height:1.6;text-align:left}.mw-parser-output .hidden-content{text-align:left}@media all and (max-width:500px){.mw-parser-output .hidden-begin{width:auto!important;clear:none!important;float:none!important}}</style><div class="hidden-begin mw-collapsible mw-collapsed" style=""><div class="hidden-title skin-nightmode-reset-color" style="text-align:center;">Where to get help</div><div class="hidden-content mw-collapsible-content" style=""> <ul><li>If you need help <b>editing or submitting your draft</b>, please <span class="plainlinks"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Wikipedia:WikiProject_Articles_for_creation/Help_desk/New_question&withJS=MediaWiki:AFCHD-wizard.js&page=Draft:Balon_(protein)"><b>ask us a question</b></a></span> at the AfC Help Desk or get <b><a href="/wiki/Wikipedia:IRC_help_disclaimer" title="Wikipedia:IRC help disclaimer">live help</a></b> from experienced editors. These venues are only for help with editing and the submission process, not to get reviews.</li> <li>If you need <b>feedback on your draft</b>, or if the review is taking a lot of time, you can try asking for help on the <a href="/wiki/Help:Talk_pages" title="Help:Talk pages">talk page</a> of a <a href="/wiki/Wikipedia:WikiProject#Finding_a_project" title="Wikipedia:WikiProject">relevant WikiProject</a>. Some WikiProjects are more active than others so a speedy reply is not guaranteed.</li></ul> </div></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1214851843"><div class="hidden-begin mw-collapsible mw-collapsed" style=""><div class="hidden-title skin-nightmode-reset-color" style="text-align:center;">How to improve a draft</div><div class="hidden-content mw-collapsible-content" style=""> <style data-mw-deduplicate="TemplateStyles:r1184024115">.mw-parser-output .div-col{margin-top:0.3em;column-width:30em}.mw-parser-output .div-col-small{font-size:90%}.mw-parser-output .div-col-rules{column-rule:1px solid #aaa}.mw-parser-output .div-col dl,.mw-parser-output .div-col ol,.mw-parser-output .div-col ul{margin-top:0}.mw-parser-output .div-col li,.mw-parser-output .div-col dd{page-break-inside:avoid;break-inside:avoid-column}</style><div class="div-col" style="column-width: 36em;"> <ul><li><a href="/wiki/Wikipedia:Contributing_to_Wikipedia" title="Wikipedia:Contributing to Wikipedia">Wikipedia:Contributing to Wikipedia</a> – a basic overview on how to edit Wikipedia.</li> <li><a href="/wiki/Help:Wikitext" title="Help:Wikitext">Help:Wikitext</a> – how to use the markup</li> <li><a href="/wiki/Help:Referencing_for_beginners" title="Help:Referencing for beginners">Help:Referencing for beginners</a> – how to include references</li> <li><a href="/wiki/Wikipedia:Article_development" title="Wikipedia:Article development">Wikipedia:Article development</a> – how to develop your article</li> <li><a href="/wiki/Wikipedia:Writing_better_articles" title="Wikipedia:Writing better articles">Wikipedia:Writing better articles</a> – how to improve your article</li> <li><a href="/wiki/Wikipedia:Verifiability" title="Wikipedia:Verifiability">Wikipedia:Verifiability</a> – make sure your article includes <a href="/wiki/Wikipedia:RS" class="mw-redirect" title="Wikipedia:RS">reliable</a> <a href="/wiki/Wikipedia:IS" class="mw-redirect" title="Wikipedia:IS">third-party sources</a></li></ul></div> <p>You can also browse <a href="/wiki/Wikipedia:Featured_articles" title="Wikipedia:Featured articles">Wikipedia:Featured articles</a> and <a href="/wiki/Wikipedia:Good_articles" title="Wikipedia:Good articles">Wikipedia:Good articles</a> to find examples of Wikipedia's best writing on topics similar to your proposed article. </p> </div></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1214851843"><div class="hidden-begin mw-collapsible mw-collapsed" style=""><div class="hidden-title skin-nightmode-reset-color" style="text-align:center;">Improving your odds of a speedy review</div><div class="hidden-content mw-collapsible-content" style=""> <p>To improve your odds of a faster review, tag your draft with relevant <a href="/wiki/Wikipedia:WikiProject" title="Wikipedia:WikiProject">WikiProject</a> tags using the button below. This will let reviewers know a new draft has been submitted in their area of interest. For instance, if you wrote about a female astronomer, you would want to add the <i>Biography</i>, <i>Astronomy</i>, and <i>Women scientists</i> tags. </p> <div style="text-align: center;"><span class="plainlinks clickbutton"><a class="external text" href="https://en.wikipedia.org/wiki/Wikipedia:WikiProject_Articles_for_creation/Add_WikiProject_tags?withJS=MediaWiki:AFC-add-project-tags.js&title=Draft:Balon_(protein)"><span class="mw-ui-button mw-ui-progressive"><b>Add tags to your draft</b></span></a></span></div></div></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1214851843"><div class="hidden-begin mw-collapsible mw-collapsed" style=""><div class="hidden-title skin-nightmode-reset-color" style="text-align:center;">Editor resources</div><div class="hidden-content mw-collapsible-content" style=""> <ul><li><i>Easy tools</i>: <a class="external text" href="https://citations.toolforge.org/process_page.php?edit=automated_tools&slow=1&page=Draft:Balon_(protein)">Citation bot</a> (<a href="/wiki/User:Citation_bot/use" title="User:Citation bot/use">help</a>) <b>|</b> <i>Advanced:</i> <a class="external text" href="https://tools.wmflabs.org/refill/result.php?page=Draft:Balon_(protein)&defaults=y">Fix bare URLs</a></li></ul> </div></div><small> Declined by <span class="plainlinks"><a class="external text" href="https://en.wikipedia.org/wiki/User:Mgp28">Mgp28</a></span> 3 months ago.</small><small> Last edited by <a href="/wiki/User:Mrfoogles" title="User:Mrfoogles">Mrfoogles</a> 6 days ago. Reviewer: <a class="external text" href="https://en.wikipedia.org/w/index.php?title=User_talk:Mrfoogles&action=edit&editintro=Template:AfC_submission/user_talk_editintro_declined&preload=Template:AfC_submission/user_talk_preload_declined&preloadtitle=Your+submission+at+%5B%5BWP%3AAfC%7CArticles+for+creation%5D%5D&section=new">Inform author</a>.</small><div style="border-top: 1px #AAA solid; margin-top:5px;"><table><tbody><tr><td><span class="plainlinks clickbutton"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Wikipedia:Articles_for_creation/Submitting&withJS=MediaWiki:AFC-submit-wizard.js&page=Draft:Balon_(protein)"><span class="mw-ui-button mw-ui-progressive">Resubmit</span></a></span></td><td>Please note that if the issues are not fixed, the draft will be declined again.</td></tr></tbody></table></div></td><td class="mbox-imageright"><figure class="mw-halign-center" typeof="mw:File"><a href="/wiki/File:AFC-Logo_Decline.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/7/7e/AFC-Logo_Decline.svg/75px-AFC-Logo_Decline.svg.png" decoding="async" width="75" height="75" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/7e/AFC-Logo_Decline.svg/113px-AFC-Logo_Decline.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/7e/AFC-Logo_Decline.svg/150px-AFC-Logo_Decline.svg.png 2x" data-file-width="48" data-file-height="48" /></a><figcaption></figcaption></figure></td></tr></tbody></table> <ul><li><span typeof="mw:File"><span><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/ba/Symbol_opinion_vote.svg/20px-Symbol_opinion_vote.svg.png" decoding="async" width="20" height="21" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/ba/Symbol_opinion_vote.svg/30px-Symbol_opinion_vote.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/ba/Symbol_opinion_vote.svg/40px-Symbol_opinion_vote.svg.png 2x" data-file-width="180" data-file-height="185" /></span></span> <span style="font-weight:bold">Comment:</span> I liked this article a lot but I cannot currently find enough sources to convince me that it meets Wikipedia's notability criteria. Given the protein is only recently discovered, I suspect it could meet the criteria in the future. In the meantime, I suggest you merge this text into <a href="/wiki/Hibernation_factor" title="Hibernation factor">Hibernation factor</a> (which you also created), then split it off once there is enough coverage in reliable sources. <a href="/wiki/User:Mgp28" title="User:Mgp28">Mgp28</a> (<a href="/wiki/User_talk:Mgp28" title="User talk:Mgp28">talk</a>) 15:37, 24 July 2024 (UTC)</li></ul> <hr /> <div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Protein used in bacterial hibernation</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238436933"><table class="plainlinks ombox ombox-notice" role="presentation"><tbody><tr><td class="mbox-image"><span typeof="mw:File"><span><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/1/1d/Information_icon4.svg/40px-Information_icon4.svg.png" decoding="async" width="40" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/1/1d/Information_icon4.svg/60px-Information_icon4.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/1/1d/Information_icon4.svg/80px-Information_icon4.svg.png 2x" data-file-width="620" data-file-height="620" /></span></span></td><td class="mbox-text">An editor has marked this as a <em>promising draft</em> and requests that, should it go unedited for six months, <a href="/wiki/Wikipedia:G13" class="mw-redirect" title="Wikipedia:G13">G13</a> deletion be postponed, either by making a <a href="/wiki/Help:Dummy_edit" title="Help:Dummy edit">dummy</a>/<a href="/wiki/Help:Minor_edit" title="Help:Minor edit">minor</a> edit to the page, or by improving and submitting it for review.<br /><span class="plainlinks"><a class="external text" href="https://en.wikipedia.org/w/index.php?title=Draft:Balon_(protein)&diff=cur">Last edited</a> by <a href="/wiki/User:Mrfoogles" title="User:Mrfoogles">Mrfoogles</a> <span class="plainlinks">(<a href="/wiki/User_talk:Mrfoogles" title="User talk:Mrfoogles">talk</a> | <a href="/wiki/Special:Contributions/Mrfoogles" title="Special:Contributions/Mrfoogles">contribs</a>)</span> 6 days ago. <i>(<a class="external text" href="https://en.wikipedia.org/w/index.php?title=Draft:Balon_(protein)&action=purge">Update</a>)</i></span></td><td class="mbox-imageright"><span typeof="mw:File"><span><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/Trash_Can_%28wish_cross%29.svg/40px-Trash_Can_%28wish_cross%29.svg.png" decoding="async" width="40" height="45" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/Trash_Can_%28wish_cross%29.svg/60px-Trash_Can_%28wish_cross%29.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/83/Trash_Can_%28wish_cross%29.svg/80px-Trash_Can_%28wish_cross%29.svg.png 2x" data-file-width="512" data-file-height="576" /></span></span></td></tr></tbody></table> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above">Balon</th></tr><tr><td colspan="2" class="infobox-image"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/File:Hibernation_factor_Msmeg1130_(Balon)_in_complex_with_Mycobacterium_smegmatis_70S_ribosome.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8e/Hibernation_factor_Msmeg1130_%28Balon%29_in_complex_with_Mycobacterium_smegmatis_70S_ribosome.png/220px-Hibernation_factor_Msmeg1130_%28Balon%29_in_complex_with_Mycobacterium_smegmatis_70S_ribosome.png" decoding="async" width="220" height="211" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8e/Hibernation_factor_Msmeg1130_%28Balon%29_in_complex_with_Mycobacterium_smegmatis_70S_ribosome.png/330px-Hibernation_factor_Msmeg1130_%28Balon%29_in_complex_with_Mycobacterium_smegmatis_70S_ribosome.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8e/Hibernation_factor_Msmeg1130_%28Balon%29_in_complex_with_Mycobacterium_smegmatis_70S_ribosome.png/440px-Hibernation_factor_Msmeg1130_%28Balon%29_in_complex_with_Mycobacterium_smegmatis_70S_ribosome.png 2x" data-file-width="1452" data-file-height="1394" /></a></span><div class="infobox-caption">A rendering of Msmeg1130 (Balon analogue) in a complex with the <a href="/wiki/Mycobacterium_smegmatis" title="Mycobacterium smegmatis">Mycobacterium smegmatis</a> ribosome. Balon in tan in the center.</div></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Symbol</th><td class="infobox-data" style="background-color: #eee">?</td></tr></tbody></table> <figure class="mw-default-size" typeof="mw:File/Thumb"><span><video id="mwe_player_0" poster="//upload.wikimedia.org/wikipedia/commons/thumb/8/85/Msmeg1130_rotating_structure.webm/220px--Msmeg1130_rotating_structure.webm.jpg" controls="" preload="none" data-mw-tmh="" class="mw-file-element" width="220" height="331" data-durationhint="5" data-mwtitle="Msmeg1130_rotating_structure.webm" data-mwprovider="wikimediacommons" resource="/wiki/File:Msmeg1130_rotating_structure.webm"><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/8/85/Msmeg1130_rotating_structure.webm/Msmeg1130_rotating_structure.webm.480p.vp9.webm" type="video/webm; codecs="vp9, opus"" data-transcodekey="480p.vp9.webm" data-width="320" data-height="480" /><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/8/85/Msmeg1130_rotating_structure.webm/Msmeg1130_rotating_structure.webm.720p.vp9.webm" type="video/webm; codecs="vp9, opus"" data-transcodekey="720p.vp9.webm" data-width="478" data-height="720" /><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/8/85/Msmeg1130_rotating_structure.webm/Msmeg1130_rotating_structure.webm.1080p.vp9.webm" type="video/webm; codecs="vp9, opus"" data-transcodekey="1080p.vp9.webm" data-width="718" data-height="1080" /><source src="//upload.wikimedia.org/wikipedia/commons/8/85/Msmeg1130_rotating_structure.webm" type="video/webm; codecs="vp9"" data-width="906" data-height="1362" /><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/8/85/Msmeg1130_rotating_structure.webm/Msmeg1130_rotating_structure.webm.144p.mjpeg.mov" type="video/quicktime" data-transcodekey="144p.mjpeg.mov" data-width="96" data-height="144" /><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/8/85/Msmeg1130_rotating_structure.webm/Msmeg1130_rotating_structure.webm.240p.vp9.webm" type="video/webm; codecs="vp9, opus"" data-transcodekey="240p.vp9.webm" data-width="160" data-height="240" /><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/8/85/Msmeg1130_rotating_structure.webm/Msmeg1130_rotating_structure.webm.360p.webm" type="video/webm; codecs="vp8, vorbis"" data-transcodekey="360p.webm" data-width="240" data-height="360" /><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/8/85/Msmeg1130_rotating_structure.webm/Msmeg1130_rotating_structure.webm.360p.vp9.webm" type="video/webm; codecs="vp9, opus"" data-transcodekey="360p.vp9.webm" data-width="240" data-height="360" /></video></span><figcaption>Msmeg1130 rotating structure</figcaption></figure> <p>Balon is a <a href="/wiki/Hibernation_factor" title="Hibernation factor">hibernation factor</a> protein found in the cold-adapted bacterium <i><a href="/wiki/Psychrobacter_urativorans" title="Psychrobacter urativorans">Psychrobacter urativorans</a>.</i><sup id="cite_ref-:1_1-0" class="reference"><a href="#cite_note-:1-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> "Balon" means "ball" in Spanish. The name was chosen to match Pelota, a possible distant homologue whose name is also a Spanish word for "ball."<sup id="cite_ref-:1_1-1" class="reference"><a href="#cite_note-:1-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Balon binds to the <a href="/wiki/Ribosome" title="Ribosome">ribosome</a> in order to halt the production of proteins, which can account for more than 50% of a cell's energy usage, when the cell enters a dormant state.<sup id="cite_ref-:0_2-0" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Unlike previously discovered hibernation factors, Balon can bind to the ribosome while protein production is in process.<sup id="cite_ref-:0_2-1" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> This is important for rapid response to stress because in some cells, protein production can take up to 20 minutes to complete.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Balon does this by rather than physically blocking the <a href="/wiki/A_site" class="mw-redirect" title="A site">A site</a> of the ribosome, as other hibernation factors do, binding near to but not across the channel, allowing it to attach to the ribosome independent of whether protein production is taking place.<sup id="cite_ref-:0_2-2" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Balon was discovered accidentally by a researcher who unintentionally left a sample of <i>P. urativorans</i> in an ice bucket for too long, <a href="/wiki/Cold_shock_response#Cold_shock_in_bacteria" title="Cold shock response">cold-shocking</a> it, through subsequent <a href="/wiki/Cryogenic_electron_microscopy" title="Cryogenic electron microscopy">cryo-EM scans</a> of the organism's ribosomes.<sup id="cite_ref-:0_2-3" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>Relatives of Balon have been found which bind to ribosome A-sites in <i><a href="/wiki/Mycobacterium_tuberculosis" title="Mycobacterium tuberculosis">Mycobacterium tuberculosis</a></i>, which causes tuberculosis, and <i><a href="/wiki/Thermus_thermophilus" title="Thermus thermophilus">Thermus thermophilus</a></i>, which lives in thermal vents<i>,</i> suggesting that it has similarly acting <a href="/wiki/Homology_(biology)" title="Homology (biology)">homologues</a> in other species.<sup id="cite_ref-:0_2-4" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Genetic relatives of Balon have been found in 20% of bacterial genomes catalogued in public databases, but were not found in <i><a href="/wiki/Escherichia_coli" title="Escherichia coli">Escherichia coli</a></i> and <i><a href="/wiki/Staphylococcus_aureus" title="Staphylococcus aureus">Staphylococcus aureus</a></i>, which are commonly used in studies of cellular dormancy.<sup id="cite_ref-:0_2-5" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Draft:Balon_(protein)&action=edit&section=1" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-:1-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-:1_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-:1_1-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFHelena-BuenoRybakEkemezieSullivan2024" class="citation journal cs1">Helena-Bueno, Karla; Rybak, Mariia Yu; Ekemezie, Chinenye L.; Sullivan, Rudi; Brown, Charlotte R.; Dingwall, Charlotte; Baslé, Arnaud; Schneider, Claudia; Connolly, James P. 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