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DRUGS","created_at":"2015-10-21T17:08:28.383-07:00","url":"https://www.academia.edu/17133058/HYPERTENSION_and_DRUGS?f_ri=145","dom_id":"work_17133058","summary":null,"downloadable_attachments":[{"id":39348690,"asset_id":17133058,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":6108536,"first_name":"magendira mani","last_name":"vinayagam","domain_name":"tvuni","page_name":"mvinayagam","display_name":"magendira mani vinayagam","profile_url":"https://tvuni.academia.edu/mvinayagam?f_ri=145","photo":"https://0.academia-photos.com/6108536/2552235/16269571/s65_magendira_mani.vinayagam.jpg"}],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_15391826" data-work_id="15391826" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/15391826/HEPATOPROTECTIVE_EFFECT_OF_MANGIFERA_INDICA_STEM_BARK_EXTRACTS_ON_PARACETAMOL_INDUCED_OXIDATIVE_STRESS_IN_ALBINO_RATS">HEPATOPROTECTIVE EFFECT OF MANGIFERA-INDICA STEM BARK EXTRACTS ON PARACETAMOL-INDUCED OXIDATIVE STRESS IN ALBINO RATS</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This study was conducted to evaluate the hepatoprotective activity of aqueous and ethanol extract of Mangifera-indica stem bark in paracetamolinduced liver injury in winstar albino rats. Aqueous and ethanolic extracts of M. indica stem... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_15391826" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This study was conducted to evaluate the hepatoprotective activity of<br />aqueous and ethanol extract of Mangifera-indica stem bark in paracetamolinduced<br />liver injury in winstar albino rats. Aqueous and ethanolic extracts of<br />M. indica stem bark at a dose of 200mg/kg were administered for 7 days to<br />rats in groups II and III respectively while vitamin C (200mg/kg) was given<br />as a standard antioxidant to group IV along with water and standard feed.<br />Groups I and V received water and standard feed for 7day. On the 8th day all<br />groups except group I received paracetamol at a dose of 2g/kg body weight<br />and all rats were sacrificed 12hrs after paracetamol administration. Serum<br />total protein (TP), albumin, aspartate transaminase (AST), alanine<br />transaminase (ALT) and alkaline phosphatase (ALP) were determined to<br />assess the effect of the extract on the paracetamol induced hepatic damage in<br />addition to hepatic antioxidant status. The ethanolic extract was found to be<br />more effective than the aqueous extract (200 mg/kg) in paracetamol induced<br />liver damage by decreasing the activity of serum enzymes AST, ALT and<br />ALP while increasing significantly (P<0.05) the levels of total proteins and<br />albumin. Glutathione (GSH), catalase (CAT) and superoxide dismutase<br />(SOD) activity were significantly increased (P<0.05) in the treated groups<br />while malondialdehyde (MDA) levels were reduced. From this studies it is<br />concluded that both aqueous and ethanol extract of M. indica stem bark<br />possesses hepatoprotective activity.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/15391826" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="71b6dab7b147d7e86950b5082fb9c4f6" rel="nofollow" data-download="{"attachment_id":38666686,"asset_id":15391826,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/38666686/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33384065" href="https://euinstitute.academia.edu/EuropeanScientificJournalESJ">European Scientific Journal ESJ</a><script data-card-contents-for-user="33384065" type="text/json">{"id":33384065,"first_name":"European Scientific Journal","last_name":"ESJ","domain_name":"euinstitute","page_name":"EuropeanScientificJournalESJ","display_name":"European Scientific Journal ESJ","profile_url":"https://euinstitute.academia.edu/EuropeanScientificJournalESJ?f_ri=145","photo":"https://0.academia-photos.com/33384065/9874609/148656532/s65_european_scientific_journal.esj.jpeg"}</script></span></span></li><li class="js-paper-rank-work_15391826 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="15391826"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 15391826, container: ".js-paper-rank-work_15391826", }); 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$(".js-view-count[data-work-id=15391826]").text(description); $(".js-view-count-work_15391826").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_15391826").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="15391826"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i></div><span class="InlineList-item-text u-textTruncate u-pl6x"><a class="InlineList-item-text" data-has-card-for-ri="145" href="https://www.academia.edu/Documents/in/Biochemistry">Biochemistry</a><script data-card-contents-for-ri="145" type="text/json">{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}</script></span></li><script>(function(){ if (false) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=15391826]'), work: {"id":15391826,"title":"HEPATOPROTECTIVE EFFECT OF MANGIFERA-INDICA STEM BARK EXTRACTS ON PARACETAMOL-INDUCED OXIDATIVE STRESS IN ALBINO RATS","created_at":"2015-09-04T06:47:23.440-07:00","url":"https://www.academia.edu/15391826/HEPATOPROTECTIVE_EFFECT_OF_MANGIFERA_INDICA_STEM_BARK_EXTRACTS_ON_PARACETAMOL_INDUCED_OXIDATIVE_STRESS_IN_ALBINO_RATS?f_ri=145","dom_id":"work_15391826","summary":"This study was conducted to evaluate the hepatoprotective activity of\naqueous and ethanol extract of Mangifera-indica stem bark in paracetamolinduced\nliver injury in winstar albino rats. Aqueous and ethanolic extracts of\nM. indica stem bark at a dose of 200mg/kg were administered for 7 days to\nrats in groups II and III respectively while vitamin C (200mg/kg) was given\nas a standard antioxidant to group IV along with water and standard feed.\nGroups I and V received water and standard feed for 7day. On the 8th day all\ngroups except group I received paracetamol at a dose of 2g/kg body weight\nand all rats were sacrificed 12hrs after paracetamol administration. Serum\ntotal protein (TP), albumin, aspartate transaminase (AST), alanine\ntransaminase (ALT) and alkaline phosphatase (ALP) were determined to\nassess the effect of the extract on the paracetamol induced hepatic damage in\naddition to hepatic antioxidant status. The ethanolic extract was found to be\nmore effective than the aqueous extract (200 mg/kg) in paracetamol induced\nliver damage by decreasing the activity of serum enzymes AST, ALT and\nALP while increasing significantly (P\u003c0.05) the levels of total proteins and\nalbumin. Glutathione (GSH), catalase (CAT) and superoxide dismutase\n(SOD) activity were significantly increased (P\u003c0.05) in the treated groups\nwhile malondialdehyde (MDA) levels were reduced. From this studies it is\nconcluded that both aqueous and ethanol extract of M. indica stem bark\npossesses hepatoprotective activity. ","downloadable_attachments":[{"id":38666686,"asset_id":15391826,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33384065,"first_name":"European Scientific Journal","last_name":"ESJ","domain_name":"euinstitute","page_name":"EuropeanScientificJournalESJ","display_name":"European Scientific Journal ESJ","profile_url":"https://euinstitute.academia.edu/EuropeanScientificJournalESJ?f_ri=145","photo":"https://0.academia-photos.com/33384065/9874609/148656532/s65_european_scientific_journal.esj.jpeg"}],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_35649637" data-work_id="35649637" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/35649637/Moringa_oleifera_A_review_of_the_medical_evidence_for_its_nutritional_and_pharmacological_properties">Moringa oleifera : A review of the medical evidence for its nutritional and pharmacological properties</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The Moringa plant provides a rich and rare combination of zeatin, quercetin, sitosterol, caffeoylquinic acid and kaempferol. In addition to its compelling water purifying powers and high nutritional value, M. oleifera is very important... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_35649637" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The Moringa plant provides a rich and rare combination of zeatin, quercetin, sitosterol, caffeoylquinic acid and kaempferol. In addition to its compelling water purifying powers and high nutritional value, M. oleifera is very important for its medicinal value. Various parts of this plant such as the leaves, roots, seed, bark, fruit, flowers and immature pods act as cardiac and circulatory stimulants, antipyretic, antitumor, anti-inflammatory, antiepileptic, diuretic, antiulcer, antispasmodic antihypertensive, cholesterol lowering, antidiabetic, antioxidant, antibacterial, hepatoprotective, and antifungal activities, and are being employed for the treatment of different ailments in the indigenous system of medicine, particularly in South Asia.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/35649637" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5e92e2b68a36a8f4e1d4132e0ce4cb53" rel="nofollow" data-download="{"attachment_id":55519179,"asset_id":35649637,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/55519179/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="26759751" href="https://bhu-in.academia.edu/MukeshKumarYadav">Mukesh Kumar Yadav</a><script data-card-contents-for-user="26759751" type="text/json">{"id":26759751,"first_name":"Mukesh Kumar","last_name":"Yadav","domain_name":"bhu-in","page_name":"MukeshKumarYadav","display_name":"Mukesh Kumar Yadav","profile_url":"https://bhu-in.academia.edu/MukeshKumarYadav?f_ri=145","photo":"https://0.academia-photos.com/26759751/18792389/18752586/s65_mukesh_kumar.yadav.jpg"}</script></span></span></li><li class="js-paper-rank-work_35649637 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="35649637"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 35649637, container: ".js-paper-rank-work_35649637", }); 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})();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_37617981" data-work_id="37617981" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/37617981/MADHUCA_LONIGFOLIA_SAPOTACEAE_A_REVIEW_OF_ITS_TRADITIONAL_USES_PHYTOCHEMISTRY_AND_PHARMACOLOGY">MADHUCA LONIGFOLIA (SAPOTACEAE): A REVIEW OF ITS TRADITIONAL USES, PHYTOCHEMISTRY AND PHARMACOLOGY</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Madhuca longifolia (Mahua) belongs to family Sapotaceae. Madhuca commonly known as the Butter nut tree is a medium to large sized deciduous tree distributed in Nepal, India and Sri Lanka. Madhuca longifolia is a large tree, about 17m high... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_37617981" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Madhuca longifolia (Mahua) belongs to family Sapotaceae. Madhuca commonly known as the Butter nut tree is a medium to large sized deciduous tree distributed in Nepal, India and Sri Lanka. Madhuca longifolia is a large tree, about 17m high with a large top. Mahua is a large, shady, deciduous tree doting much of the central Indian landscape, both wild and cultivated. Mahua seeds are of economic importance as they are good source of edible fats. Medicinal herbs are moving from fringe to mainstream use with a great number of people seeking remedies and health approaches free from side effects caused by synthetic chemicals. Madhuca longifolia is reported to contain sapogenins, triterpenoids, steroids, saponins, flavonoids and glycosides. It is used as spasmogenic, oxytocic, uterotonic, anti-bacterial, anti-implantation, anti-tumour, anti-progestational, antiestrogenic activity against menorrhagia and anti-cancer. This review contains the traditional uses of various parts of plant, Phytochemical constituent and different reported pharmacological activity.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/37617981" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8e80010f0b1fc21c1f4bf24734166639" rel="nofollow" data-download="{"attachment_id":57601029,"asset_id":37617981,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/57601029/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3318863" href="https://ssjournals.academia.edu/ScholarScienceJournals">Scholar Science Journals</a><script data-card-contents-for-user="3318863" type="text/json">{"id":3318863,"first_name":"Scholar Science","last_name":"Journals","domain_name":"ssjournals","page_name":"ScholarScienceJournals","display_name":"Scholar Science Journals","profile_url":"https://ssjournals.academia.edu/ScholarScienceJournals?f_ri=145","photo":"https://0.academia-photos.com/3318863/1108470/20363147/s65_scholar_science.journals.png"}</script></span></span></li><li class="js-paper-rank-work_37617981 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="37617981"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 37617981, container: ".js-paper-rank-work_37617981", }); 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Madhuca commonly known as the Butter nut tree is a medium to large sized deciduous tree distributed in Nepal, India and Sri Lanka. Madhuca longifolia is a large tree, about 17m high with a large top. Mahua is a large, shady, deciduous tree doting much of the central Indian landscape, both wild and cultivated. Mahua seeds are of economic importance as they are good source of edible fats. Medicinal herbs are moving from fringe to mainstream use with a great number of people seeking remedies and health approaches free from side effects caused by synthetic chemicals. Madhuca longifolia is reported to contain sapogenins, triterpenoids, steroids, saponins, flavonoids and glycosides. It is used as spasmogenic, oxytocic, uterotonic, anti-bacterial, anti-implantation, anti-tumour, anti-progestational, antiestrogenic activity against menorrhagia and anti-cancer. This review contains the traditional uses of various parts of plant, Phytochemical constituent and different reported pharmacological activity.","downloadable_attachments":[{"id":57601029,"asset_id":37617981,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3318863,"first_name":"Scholar Science","last_name":"Journals","domain_name":"ssjournals","page_name":"ScholarScienceJournals","display_name":"Scholar Science Journals","profile_url":"https://ssjournals.academia.edu/ScholarScienceJournals?f_ri=145","photo":"https://0.academia-photos.com/3318863/1108470/20363147/s65_scholar_science.journals.png"}],"research_interests":[{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology?f_ri=145","nofollow":false},{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false},{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy?f_ri=145","nofollow":false},{"id":4553,"name":"Toxicology","url":"https://www.academia.edu/Documents/in/Toxicology?f_ri=145","nofollow":false},{"id":2434017,"name":"International Journal of Biomedical Research","url":"https://www.academia.edu/Documents/in/International_Journal_of_Biomedical_Research?f_ri=145"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_36222497" data-work_id="36222497" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/36222497/Wood_preservation_using_natural_products_Preservaci%C3%B3n_de_la_madera_usando_productos_naturales">Wood preservation using natural products Preservación de la madera usando productos naturales</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">AbstrAct It is a current concern in the wood preservation field to avoid the use of toxic chemicals and develop new technologies based on low environmental impact agents and sustainable principles. Under this expectation, an intended... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_36222497" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">AbstrAct It is a current concern in the wood preservation field to avoid the use of toxic chemicals and develop new technologies based on low environmental impact agents and sustainable principles. Under this expectation, an intended state-of-the-art is introduced on the application of natural products such as traditional tar and wood oils as well as tannins and plant extracts. A particular revision to heartwood chemical components is offered. The combined methods of using natural and chemical components are reviewed, considering as outstanding the mixtures of natural organic constituents with cooper and boron salts that seem to be under encouraging experimentation. Fungicides and anti-termite applications are commented as well the leaching problem of inorganic salts. Chemical modification of wood structure through the formation of adducts and the treatment with nanomaterials are promising tools that will change the actual view and performance of wood preservation techniques. resumen Una de las prioridades actuales en el campo de la preservación de madera es evitar el uso de materiales tóxicos, desarrollando nuevas tecnologías fundamentadas en principios sustentables y empleando agentes de bajo impacto ambiental. Con esta expectativa se plantea una revisión del estado del arte sobre la aplicación de productos naturales, tales como taninos, alquitrán, aceites y extractos vegetales. Se presenta en particular una revisión sobre los componentes químicos contenidos en el duramen de maderas naturalmente resistentes. Se analizan los métodos combinados de ingredientes naturales y químicos, resaltando las mezclas de componentes naturales orgánicos con sales de cobre y boro que parecen representar una opción experimental confiable. Se comentan también las aplicaciones fungicidas y anti termitas, así como los problemas de lixiviación de sales inorgánicas. Opciones como la modificación química de la madera vía la formación de aductos y por tratamiento con nanomateriales son procesos promisorios que cambiaran eventualmente la manera de ver y aplicar la tecnología actual de preservación de maderas.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/36222497" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="43c90d8db6a836bc19b503c9dc329ff6" rel="nofollow" data-download="{"attachment_id":56125275,"asset_id":36222497,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/56125275/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="5415159" href="https://itdurango.academia.edu/RubenGonzalez">Ruben Gonzalez</a><script data-card-contents-for-user="5415159" type="text/json">{"id":5415159,"first_name":"Ruben","last_name":"Gonzalez","domain_name":"itdurango","page_name":"RubenGonzalez","display_name":"Ruben Gonzalez","profile_url":"https://itdurango.academia.edu/RubenGonzalez?f_ri=145","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_36222497 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="36222497"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 36222497, container: ".js-paper-rank-work_36222497", }); 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Under this expectation, an intended state-of-the-art is introduced on the application of natural products such as traditional tar and wood oils as well as tannins and plant extracts. A particular revision to heartwood chemical components is offered. The combined methods of using natural and chemical components are reviewed, considering as outstanding the mixtures of natural organic constituents with cooper and boron salts that seem to be under encouraging experimentation. Fungicides and anti-termite applications are commented as well the leaching problem of inorganic salts. Chemical modification of wood structure through the formation of adducts and the treatment with nanomaterials are promising tools that will change the actual view and performance of wood preservation techniques. resumen Una de las prioridades actuales en el campo de la preservación de madera es evitar el uso de materiales tóxicos, desarrollando nuevas tecnologías fundamentadas en principios sustentables y empleando agentes de bajo impacto ambiental. Con esta expectativa se plantea una revisión del estado del arte sobre la aplicación de productos naturales, tales como taninos, alquitrán, aceites y extractos vegetales. Se presenta en particular una revisión sobre los componentes químicos contenidos en el duramen de maderas naturalmente resistentes. Se analizan los métodos combinados de ingredientes naturales y químicos, resaltando las mezclas de componentes naturales orgánicos con sales de cobre y boro que parecen representar una opción experimental confiable. Se comentan también las aplicaciones fungicidas y anti termitas, así como los problemas de lixiviación de sales inorgánicas. Opciones como la modificación química de la madera vía la formación de aductos y por tratamiento con nanomateriales son procesos promisorios que cambiaran eventualmente la manera de ver y aplicar la tecnología actual de preservación de maderas.","downloadable_attachments":[{"id":56125275,"asset_id":36222497,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":5415159,"first_name":"Ruben","last_name":"Gonzalez","domain_name":"itdurango","page_name":"RubenGonzalez","display_name":"Ruben Gonzalez","profile_url":"https://itdurango.academia.edu/RubenGonzalez?f_ri=145","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":72,"name":"Chemical Engineering","url":"https://www.academia.edu/Documents/in/Chemical_Engineering?f_ri=145","nofollow":false},{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false},{"id":4553,"name":"Toxicology","url":"https://www.academia.edu/Documents/in/Toxicology?f_ri=145","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_19931496" data-work_id="19931496" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/19931496/Sodium_bicarbonate">Sodium bicarbonate</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button 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type="text/json">{"id":68,"name":"Bioengineering","url":"https://www.academia.edu/Documents/in/Bioengineering?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="140" href="https://www.academia.edu/Documents/in/Pharmacology">Pharmacology</a>, <script data-card-contents-for-ri="140" type="text/json">{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="145" href="https://www.academia.edu/Documents/in/Biochemistry">Biochemistry</a>, <script data-card-contents-for-ri="145" type="text/json">{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="159" href="https://www.academia.edu/Documents/in/Microbiology">Microbiology</a><script data-card-contents-for-ri="159" 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});</script></span><script>$(function() { $(".js-view-count-work_6394049").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="6394049"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i> <a class="InlineList-item-text u-positionRelative">45</a> </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="140" href="https://www.academia.edu/Documents/in/Pharmacology">Pharmacology</a>, <script data-card-contents-for-ri="140" type="text/json">{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="145" href="https://www.academia.edu/Documents/in/Biochemistry">Biochemistry</a>, <script data-card-contents-for-ri="145" type="text/json">{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="146" href="https://www.academia.edu/Documents/in/Bioinformatics">Bioinformatics</a>, <script data-card-contents-for-ri="146" type="text/json">{"id":146,"name":"Bioinformatics","url":"https://www.academia.edu/Documents/in/Bioinformatics?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="155" href="https://www.academia.edu/Documents/in/Evolutionary_Biology">Evolutionary Biology</a><script data-card-contents-for-ri="155" type="text/json">{"id":155,"name":"Evolutionary Biology","url":"https://www.academia.edu/Documents/in/Evolutionary_Biology?f_ri=145","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=6394049]'), work: {"id":6394049,"title":"The chess 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itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13901665/CHEMICAL_AND_MINERAL_COMPOSITIONS_OF_WATER_EXTRACTS_OF_ZOBO_Hibiscus_sabdariffa_">CHEMICAL AND MINERAL COMPOSITIONS OF WATER EXTRACTS OF ZOBO (Hibiscus sabdariffa)</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">ABSTRACT This work was carried out to investigate the chemical/mineral composition of the water extract of zobo (Hibiscus sabdariffa) drink using the modern atomic absorption spectrophotometer. Zobo drink is a popular drink in the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13901665" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">ABSTRACT<br />This work was carried out to investigate the chemical/mineral composition of the water extract of zobo (Hibiscus sabdariffa) drink using the modern atomic absorption spectrophotometer. Zobo drink is a popular drink in the Nigeria, especially in the northern part of Nigeria. The result of the analysis indicated that the drink is high in vital mineral nutrients required for the healthy growth by humans and for the proper metabolic processes to be adequately maintained. Zobo drink is high, as indicated in the result, in iron – a major component of the human haemoglobin, when compared with other leaf like the popular vegetable leaf known as awa (Piper methysticum).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13901665" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cb205b9e1084da7b7a2a35164167608c" rel="nofollow" data-download="{"attachment_id":38155504,"asset_id":13901665,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/38155504/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="9471698" href="https://independent.academia.edu/Aridedon">Okafor Osita</a><script data-card-contents-for-user="9471698" type="text/json">{"id":9471698,"first_name":"Okafor","last_name":"Osita","domain_name":"independent","page_name":"Aridedon","display_name":"Okafor Osita","profile_url":"https://independent.academia.edu/Aridedon?f_ri=145","photo":"https://0.academia-photos.com/9471698/3321629/3908672/s65_okafor.osita.jpg"}</script></span></span></li><li class="js-paper-rank-work_13901665 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13901665"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13901665, container: ".js-paper-rank-work_13901665", }); 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$(".js-view-count[data-work-id=13901665]").text(description); $(".js-view-count-work_13901665").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13901665").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13901665"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i> <a class="InlineList-item-text u-positionRelative">8</a> </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="145" href="https://www.academia.edu/Documents/in/Biochemistry">Biochemistry</a>, <script data-card-contents-for-ri="145" type="text/json">{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="523" href="https://www.academia.edu/Documents/in/Chemistry">Chemistry</a>, <script data-card-contents-for-ri="523" type="text/json">{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="2467" href="https://www.academia.edu/Documents/in/Conservation_Biology">Conservation Biology</a>, <script data-card-contents-for-ri="2467" type="text/json">{"id":2467,"name":"Conservation Biology","url":"https://www.academia.edu/Documents/in/Conservation_Biology?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="2513" href="https://www.academia.edu/Documents/in/Molecular_Biology">Molecular Biology</a><script data-card-contents-for-ri="2513" type="text/json">{"id":2513,"name":"Molecular Biology","url":"https://www.academia.edu/Documents/in/Molecular_Biology?f_ri=145","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13901665]'), work: {"id":13901665,"title":"CHEMICAL AND MINERAL COMPOSITIONS OF WATER EXTRACTS OF ZOBO (Hibiscus sabdariffa)","created_at":"2015-07-10T19:15:37.215-07:00","url":"https://www.academia.edu/13901665/CHEMICAL_AND_MINERAL_COMPOSITIONS_OF_WATER_EXTRACTS_OF_ZOBO_Hibiscus_sabdariffa_?f_ri=145","dom_id":"work_13901665","summary":"ABSTRACT\nThis work was carried out to investigate the chemical/mineral composition of the water extract of zobo (Hibiscus sabdariffa) drink using the modern atomic absorption spectrophotometer. Zobo drink is a popular drink in the Nigeria, especially in the northern part of Nigeria. The result of the analysis indicated that the drink is high in vital mineral nutrients required for the healthy growth by humans and for the proper metabolic processes to be adequately maintained. Zobo drink is high, as indicated in the result, in iron – a major component of the human haemoglobin, when compared with other leaf like the popular vegetable leaf known as awa (Piper methysticum).\n","downloadable_attachments":[{"id":38155504,"asset_id":13901665,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":9471698,"first_name":"Okafor","last_name":"Osita","domain_name":"independent","page_name":"Aridedon","display_name":"Okafor Osita","profile_url":"https://independent.academia.edu/Aridedon?f_ri=145","photo":"https://0.academia-photos.com/9471698/3321629/3908672/s65_okafor.osita.jpg"}],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false},{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry?f_ri=145","nofollow":false},{"id":2467,"name":"Conservation Biology","url":"https://www.academia.edu/Documents/in/Conservation_Biology?f_ri=145","nofollow":false},{"id":2513,"name":"Molecular Biology","url":"https://www.academia.edu/Documents/in/Molecular_Biology?f_ri=145","nofollow":false},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=145"},{"id":18491,"name":"Molecular Biochemistry","url":"https://www.academia.edu/Documents/in/Molecular_Biochemistry?f_ri=145"},{"id":34478,"name":"Food Science and Technology","url":"https://www.academia.edu/Documents/in/Food_Science_and_Technology?f_ri=145"},{"id":221692,"name":"Sciences du langage","url":"https://www.academia.edu/Documents/in/Sciences_du_langage?f_ri=145"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_30100631" data-work_id="30100631" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/30100631/IDENTIFICATION_OF_THE_CARBOHYDRATE_COMPONENTS_OF_SOUR_SOP_ANNONA_MURICATA_PULP_PEELS_docx">IDENTIFICATION OF THE CARBOHYDRATE COMPONENTS OF SOUR SOP (ANNONA MURICATA) PULP PEELS.docx</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This study evaluates the percentage content of carbohydrate components present in sour sop pulp peels. The samples were washed and dried at 60oC for eighteen hours; this was done to prevent the volatilization of some components at higher... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_30100631" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This study evaluates the percentage content of carbohydrate components present in sour sop pulp peels. The samples were washed and dried at 60oC for eighteen hours; this was done to prevent the volatilization of some components at higher temperatures. The carbohydrate components that were determined included starch, lignin, cellulose, hemicelluloses, holocellulose and reducing sugar. Standard methods were used to determine the various parameters. Results showed that starch, lignin, cellulose, hemicelluloses, holocellulose and reducing sugar had percentage concentrations of 0.25%, 14.7%, 20%, 15%, 34% and 14.3% respectively. This study shows that the peels of sour sop pulp have some industrial potentials especially in the production of paper and low cost ethanol.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/30100631" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7e39a33a4045005fb66313cc4f69c6db" rel="nofollow" data-download="{"attachment_id":50562531,"asset_id":30100631,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50562531/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="19592173" href="https://uniport.academia.edu/marcelchuks">Chuks M Maduba</a><script data-card-contents-for-user="19592173" type="text/json">{"id":19592173,"first_name":"Chuks","last_name":"Maduba","domain_name":"uniport","page_name":"marcelchuks","display_name":"Chuks M Maduba","profile_url":"https://uniport.academia.edu/marcelchuks?f_ri=145","photo":"https://0.academia-photos.com/19592173/15032378/15763173/s65_marcel.chuks.jpg"}</script></span></span></li><li class="js-paper-rank-work_30100631 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="30100631"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 30100631, container: ".js-paper-rank-work_30100631", }); 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$(".js-view-count[data-work-id=30100631]").text(description); $(".js-view-count-work_30100631").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_30100631").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="30100631"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i> <a class="InlineList-item-text u-positionRelative">2</a> </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="145" href="https://www.academia.edu/Documents/in/Biochemistry">Biochemistry</a>, <script data-card-contents-for-ri="145" type="text/json">{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="402" href="https://www.academia.edu/Documents/in/Environmental_Science">Environmental Science</a><script data-card-contents-for-ri="402" type="text/json">{"id":402,"name":"Environmental Science","url":"https://www.academia.edu/Documents/in/Environmental_Science?f_ri=145","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=30100631]'), work: {"id":30100631,"title":"IDENTIFICATION OF THE CARBOHYDRATE COMPONENTS OF SOUR SOP (ANNONA MURICATA) PULP PEELS.docx","created_at":"2016-11-26T14:22:21.106-08:00","url":"https://www.academia.edu/30100631/IDENTIFICATION_OF_THE_CARBOHYDRATE_COMPONENTS_OF_SOUR_SOP_ANNONA_MURICATA_PULP_PEELS_docx?f_ri=145","dom_id":"work_30100631","summary":"This study evaluates the percentage content of carbohydrate components present in sour sop pulp peels. The samples were washed and dried at 60oC for eighteen hours; this was done to prevent the volatilization of some components at higher temperatures. The carbohydrate components that were determined included starch, lignin, cellulose, hemicelluloses, holocellulose and reducing sugar. Standard methods were used to determine the various parameters. Results showed that starch, lignin, cellulose, hemicelluloses, holocellulose and reducing sugar had percentage concentrations of 0.25%, 14.7%, 20%, 15%, 34% and 14.3% respectively. This study shows that the peels of sour sop pulp have some industrial potentials especially in the production of paper and low cost ethanol.","downloadable_attachments":[{"id":50562531,"asset_id":30100631,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":19592173,"first_name":"Chuks","last_name":"Maduba","domain_name":"uniport","page_name":"marcelchuks","display_name":"Chuks M Maduba","profile_url":"https://uniport.academia.edu/marcelchuks?f_ri=145","photo":"https://0.academia-photos.com/19592173/15032378/15763173/s65_marcel.chuks.jpg"}],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false},{"id":402,"name":"Environmental Science","url":"https://www.academia.edu/Documents/in/Environmental_Science?f_ri=145","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_28490364 coauthored" data-work_id="28490364" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/28490364/Mobile_genetic_elements_the_agents_of_open_source_evolution">Mobile genetic elements: the agents of open source evolution</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/28490364" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8f46b36776c3e424df4ba2654556efec" rel="nofollow" data-download="{"attachment_id":48838381,"asset_id":28490364,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48838381/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="15811561" href="https://uga.academia.edu/AnneSummers">Anne Summers</a><script data-card-contents-for-user="15811561" type="text/json">{"id":15811561,"first_name":"Anne","last_name":"Summers","domain_name":"uga","page_name":"AnneSummers","display_name":"Anne Summers","profile_url":"https://uga.academia.edu/AnneSummers?f_ri=145","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-28490364">+1</span><div class="hidden js-additional-users-28490364"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/AToussaint1">A. 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CA is known to have incomplete oral bioavailability (30–50%) due to its poor solubility and enzymatic conversion to... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_75280990" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Cefuroxime axetil (CA) is an oral cephalosporin which hydrolyzes rapidly to the active parent compound cefuroxime. CA is known to have incomplete oral bioavailability (30–50%) due to its poor solubility and enzymatic conversion to cefuroxime in the gut lumen. In order to overcome these drawbacks, a lipid-based self-nanoemulsifying drug delivery system (SNEDDS) has been developed and optimized. The SNEDDS formulations were prepared using the aqueous phase titration method. The greatest self-emulsifying area was found in the 2:1 Smix ratio. As a result, different SNEDDS formulations were carefully selected from this phase diagram based on their smaller droplet size < 100 nm, polydispersity index ≤ 0.5, dispersibility (Grade A), and transmittance (%) > 85%. Thermodynamic stability tests were carried out in order to rule out any metastable/unstable SNEDDS formulations. The droplet size, polydispersity index, zeta potential, and entrapment efficiency (% EE) of optimized CA-loaded SNEDDS (C-3) were 18.50 ± 1.83 nm, 0.064 ± 0.008, −22.12 ± 1.20 mV, and 97.62 ± 1.06%, respectively. In vitro release studies revealed that the SNEDDS formulation had increased CA solubility. CA-SNEDDS-C3 increased CA cellular uptake, possibly due to increased CA solubility and the inhibition of enzymatic conversion to cefuroxime. Finally, in terms of the improvement of oral bioavailability, CA-loaded-SNEDDS could be a viable alternative to commercially available CA formulations.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/75280990" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4ee68c77c892860518b73f1d74b4e2de" rel="nofollow" data-download="{"attachment_id":83113107,"asset_id":75280990,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/83113107/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3842921" href="https://kaust.academia.edu/MariuszJaremko">Mariusz Jaremko</a><script data-card-contents-for-user="3842921" type="text/json">{"id":3842921,"first_name":"Mariusz","last_name":"Jaremko","domain_name":"kaust","page_name":"MariuszJaremko","display_name":"Mariusz Jaremko","profile_url":"https://kaust.academia.edu/MariuszJaremko?f_ri=145","photo":"https://0.academia-photos.com/3842921/1407725/1729039/s65_mariusz.antypater.jpg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-75280990">+2</span><div class="hidden js-additional-users-75280990"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/ArshadKhan624">Arshad Khan</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/YogeshYadav289">Yogesh Yadav</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-75280990'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-75280990').html(); 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CA is known to have incomplete oral bioavailability (30–50%) due to its poor solubility and enzymatic conversion to cefuroxime in the gut lumen. In order to overcome these drawbacks, a lipid-based self-nanoemulsifying drug delivery system (SNEDDS) has been developed and optimized. The SNEDDS formulations were prepared using the aqueous phase titration method. The greatest self-emulsifying area was found in the 2:1 Smix ratio. As a result, different SNEDDS formulations were carefully selected from this phase diagram based on their smaller droplet size \u003c 100 nm, polydispersity index ≤ 0.5, dispersibility (Grade A), and transmittance (%) \u003e 85%. Thermodynamic stability tests were carried out in order to rule out any metastable/unstable SNEDDS formulations. The droplet size, polydispersity index, zeta potential, and entrapment efficiency (% EE) of optimized CA-loaded SNEDDS (C-3) were 18.50 ± 1.83 nm, 0.064 ± 0.008, −22.12 ± 1.20 mV, and 97.62 ± 1.06%, respectively. In vitro release studies revealed that the SNEDDS formulation had increased CA solubility. CA-SNEDDS-C3 increased CA cellular uptake, possibly due to increased CA solubility and the inhibition of enzymatic conversion to cefuroxime. Finally, in terms of the improvement of oral bioavailability, CA-loaded-SNEDDS could be a viable alternative to commercially available CA formulations.","downloadable_attachments":[{"id":83113107,"asset_id":75280990,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3842921,"first_name":"Mariusz","last_name":"Jaremko","domain_name":"kaust","page_name":"MariuszJaremko","display_name":"Mariusz Jaremko","profile_url":"https://kaust.academia.edu/MariuszJaremko?f_ri=145","photo":"https://0.academia-photos.com/3842921/1407725/1729039/s65_mariusz.antypater.jpg"},{"id":220595783,"first_name":"Arshad","last_name":"Khan","domain_name":"independent","page_name":"ArshadKhan624","display_name":"Arshad Khan","profile_url":"https://independent.academia.edu/ArshadKhan624?f_ri=145","photo":"/images/s65_no_pic.png"},{"id":220467819,"first_name":"Yogesh","last_name":"Yadav","domain_name":"independent","page_name":"YogeshYadav289","display_name":"Yogesh 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js-work-link" href="https://www.academia.edu/71515961/A_Population_Based_Ant_Colony_Optimization_Approach_for_DNA_Sequence_Optimization">A Population-Based Ant Colony Optimization Approach for DNA Sequence Optimization</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">DNA computing is a new computing paradigm which uses bio-molecular as information storage media and biochemical tools as information processing operators. It has shows many successful and promising results for various applications. Since... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_71515961" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">DNA computing is a new computing paradigm which uses bio-molecular as information storage media and biochemical tools as information processing operators. It has shows many successful and promising results for various applications. Since DNA reactions are probabilistic reactions, it can cause the different results for the same situations, which can be regarded as errors in the computation. To overcome the drawbacks, much works have focused to design the error-minimized DNA sequences to improve the reliability of DNA computing. In this research, Population-based ACO (P-ACO) is proposed to solve the DNA sequence optimization. P-ACO approach is a meta-heuristic algorithm that uses some ants to obtain the solutions based on the pheromone in their colony. The DNA sequence design problem is modelled by four nodes, representing four DNA bases (A, T, C, and G). The results from the proposed algorithm are compared with other sequence design methods, which are Genetic Algorithm (GA), and Mult...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/71515961" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="101277564" href="https://independent.academia.edu/AlexTrikurnia">Tri Kurniawan</a><script data-card-contents-for-user="101277564" type="text/json">{"id":101277564,"first_name":"Tri","last_name":"Kurniawan","domain_name":"independent","page_name":"AlexTrikurnia","display_name":"Tri Kurniawan","profile_url":"https://independent.academia.edu/AlexTrikurnia?f_ri=145","photo":"https://0.academia-photos.com/101277564/22167064/21398746/s65_alex.trikurnia.jpg"}</script></span></span></li><li class="js-paper-rank-work_71515961 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="71515961"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 71515961, container: ".js-paper-rank-work_71515961", }); 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type="text/json">{"id":7333,"name":"Nuclear Magnetic Resonance","url":"https://www.academia.edu/Documents/in/Nuclear_Magnetic_Resonance?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="21732" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Spectroscopy">Magnetic Resonance Spectroscopy</a>, <script data-card-contents-for-ri="21732" type="text/json">{"id":21732,"name":"Magnetic Resonance Spectroscopy","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Spectroscopy?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="48057" href="https://www.academia.edu/Documents/in/DNA">DNA</a><script data-card-contents-for-ri="48057" type="text/json">{"id":48057,"name":"DNA","url":"https://www.academia.edu/Documents/in/DNA?f_ri=145","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=47072842]'), work: {"id":47072842,"title":"Monovalent cation induced structural transitions in telomeric DNAs: G-DNA folding intermediates","created_at":"2021-04-20T16:55:31.112-07:00","url":"https://www.academia.edu/47072842/Monovalent_cation_induced_structural_transitions_in_telomeric_DNAs_G_DNA_folding_intermediates?f_ri=145","dom_id":"work_47072842","summary":null,"downloadable_attachments":[{"id":66362089,"asset_id":47072842,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":65988902,"first_name":"Eric","last_name":"Henderson","domain_name":"iastate","page_name":"EricHenderson","display_name":"Eric R Henderson","profile_url":"https://iastate.academia.edu/EricHenderson?f_ri=145","photo":"https://0.academia-photos.com/65988902/18785394/42423934/s65_eric.henderson.jpg"}],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false},{"id":7333,"name":"Nuclear Magnetic Resonance","url":"https://www.academia.edu/Documents/in/Nuclear_Magnetic_Resonance?f_ri=145","nofollow":false},{"id":21732,"name":"Magnetic Resonance Spectroscopy","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Spectroscopy?f_ri=145","nofollow":false},{"id":48057,"name":"DNA","url":"https://www.academia.edu/Documents/in/DNA?f_ri=145","nofollow":false},{"id":53108,"name":"Phosphorus","url":"https://www.academia.edu/Documents/in/Phosphorus?f_ri=145"},{"id":76407,"name":"Circular Dichroism","url":"https://www.academia.edu/Documents/in/Circular_Dichroism?f_ri=145"},{"id":119259,"name":"Magnetic Resonance","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance?f_ri=145"},{"id":170274,"name":"Dictyostelium","url":"https://www.academia.edu/Documents/in/Dictyostelium?f_ri=145"},{"id":562751,"name":"Magnetic Circular Dichroism","url":"https://www.academia.edu/Documents/in/Magnetic_Circular_Dichroism?f_ri=145"},{"id":759403,"name":"Gel electrophoresis","url":"https://www.academia.edu/Documents/in/Gel_electrophoresis?f_ri=145"},{"id":809882,"name":"Base Sequence","url":"https://www.academia.edu/Documents/in/Base_Sequence?f_ri=145"},{"id":1228946,"name":"Physical Properties","url":"https://www.academia.edu/Documents/in/Physical_Properties?f_ri=145"},{"id":1256744,"name":"Organic Compound","url":"https://www.academia.edu/Documents/in/Organic_Compound?f_ri=145"},{"id":1362652,"name":"Nucleic Acid Conformation","url":"https://www.academia.edu/Documents/in/Nucleic_Acid_Conformation?f_ri=145"},{"id":1681026,"name":"Biochemistry and cell biology","url":"https://www.academia.edu/Documents/in/Biochemistry_and_cell_biology?f_ri=145"},{"id":1724844,"name":"Molecular Structure","url":"https://www.academia.edu/Documents/in/Molecular_Structure?f_ri=145"},{"id":1727314,"name":"Nucleic Acid","url":"https://www.academia.edu/Documents/in/Nucleic_Acid?f_ri=145"},{"id":2197683,"name":"Folding Intermediate","url":"https://www.academia.edu/Documents/in/Folding_Intermediate?f_ri=145"},{"id":3789880,"name":"Medical biochemistry and metabolomics","url":"https://www.academia.edu/Documents/in/Medical_biochemistry_and_metabolomics?f_ri=145"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_45091507" data-work_id="45091507" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/45091507/RESEARCH_ON_THE_CONTENT_OF_ESSENTIAL_OILS_FLAVONOIDS_PHENOLIC_AND_POLYPHENOLIC_COMPOUNDS_IN_PARSLEY_PETROSELINUM_CRISPUM_MILL">RESEARCH ON THE CONTENT OF ESSENTIAL OILS, FLAVONOIDS, PHENOLIC AND POLYPHENOLIC COMPOUNDS IN PARSLEY (PETROSELINUM CRISPUM MILL</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This paper presents researches regarding the content of essential oils, flavonoids, polyphenolic and phenolic compounds in leaf parsley from an organic culture and the methods of extraction used for determinations. The obtained results... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_45091507" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This paper presents researches regarding the content of essential oils, flavonoids, polyphenolic and phenolic compounds in leaf parsley from an organic culture and the methods of extraction used for determinations. The obtained results highlight the medicinal properties of parsley, both the alimentary and economic importance, as a vegetable aromatic plant used for human consumption worlwide.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/45091507" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8afd776e2f0acec57f76d001cc15a360" rel="nofollow" data-download="{"attachment_id":65652985,"asset_id":45091507,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/65652985/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="62735386" href="https://univ-ovidius.academia.edu/DanRazvanPopoviciu">Dan Razvan Popoviciu</a><script data-card-contents-for-user="62735386" type="text/json">{"id":62735386,"first_name":"Dan Razvan","last_name":"Popoviciu","domain_name":"univ-ovidius","page_name":"DanRazvanPopoviciu","display_name":"Dan Razvan Popoviciu","profile_url":"https://univ-ovidius.academia.edu/DanRazvanPopoviciu?f_ri=145","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_45091507 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="45091507"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 45091507, container: ".js-paper-rank-work_45091507", }); 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$(".js-view-count[data-work-id=45091507]").text(description); $(".js-view-count-work_45091507").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_45091507").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="45091507"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i> <a class="InlineList-item-text u-positionRelative">6</a> </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="145" href="https://www.academia.edu/Documents/in/Biochemistry">Biochemistry</a>, <script data-card-contents-for-ri="145" type="text/json">{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1042" href="https://www.academia.edu/Documents/in/Horticulture">Horticulture</a>, <script data-card-contents-for-ri="1042" type="text/json">{"id":1042,"name":"Horticulture","url":"https://www.academia.edu/Documents/in/Horticulture?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="10221" href="https://www.academia.edu/Documents/in/Food_and_Nutrition">Food and Nutrition</a>, <script data-card-contents-for-ri="10221" type="text/json">{"id":10221,"name":"Food and Nutrition","url":"https://www.academia.edu/Documents/in/Food_and_Nutrition?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="51711" href="https://www.academia.edu/Documents/in/Antioxidants">Antioxidants</a><script data-card-contents-for-ri="51711" type="text/json">{"id":51711,"name":"Antioxidants","url":"https://www.academia.edu/Documents/in/Antioxidants?f_ri=145","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=45091507]'), work: {"id":45091507,"title":"RESEARCH ON THE CONTENT OF ESSENTIAL OILS, FLAVONOIDS, PHENOLIC AND POLYPHENOLIC COMPOUNDS IN PARSLEY (PETROSELINUM CRISPUM MILL","created_at":"2021-02-10T02:49:53.185-08:00","url":"https://www.academia.edu/45091507/RESEARCH_ON_THE_CONTENT_OF_ESSENTIAL_OILS_FLAVONOIDS_PHENOLIC_AND_POLYPHENOLIC_COMPOUNDS_IN_PARSLEY_PETROSELINUM_CRISPUM_MILL?f_ri=145","dom_id":"work_45091507","summary":"This paper presents researches regarding the content of essential oils, flavonoids, polyphenolic and phenolic compounds in leaf parsley from an organic culture and the methods of extraction used for determinations. The obtained results highlight the medicinal properties of parsley, both the alimentary and economic importance, as a vegetable aromatic plant used for human consumption worlwide.","downloadable_attachments":[{"id":65652985,"asset_id":45091507,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":62735386,"first_name":"Dan Razvan","last_name":"Popoviciu","domain_name":"univ-ovidius","page_name":"DanRazvanPopoviciu","display_name":"Dan Razvan Popoviciu","profile_url":"https://univ-ovidius.academia.edu/DanRazvanPopoviciu?f_ri=145","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false},{"id":1042,"name":"Horticulture","url":"https://www.academia.edu/Documents/in/Horticulture?f_ri=145","nofollow":false},{"id":10221,"name":"Food and Nutrition","url":"https://www.academia.edu/Documents/in/Food_and_Nutrition?f_ri=145","nofollow":false},{"id":51711,"name":"Antioxidants","url":"https://www.academia.edu/Documents/in/Antioxidants?f_ri=145","nofollow":false},{"id":70043,"name":"Polyphenols","url":"https://www.academia.edu/Documents/in/Polyphenols?f_ri=145"},{"id":79216,"name":"Essential oils","url":"https://www.academia.edu/Documents/in/Essential_oils?f_ri=145"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_37543001" data-work_id="37543001" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/37543001/NEW_METHOD_FOR_EXTRACTING_PHYTOCONSTITUENTS_FROM_PLANTS">NEW METHOD FOR EXTRACTING PHYTOCONSTITUENTS FROM PLANTS</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The present work is in the technical field of plant extraction. More particularly, the work relates to the extraction of medicinal plants using liquid nitrogen in a closed environment. The principal objective of this work is to provide a... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_37543001" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The present work is in the technical field of plant extraction. More particularly, the work relates to the extraction of medicinal plants using liquid nitrogen in a closed environment. The principal objective of this work is to provide a new method of plant extraction using liquid nitrogen which is simple, safe and less time consuming as compared to the existing open method of plant extraction using liquid nitrogen. The plant used for the study was Cynodon dactylon (Linn.) Pers. The new method includes the steps of size reduction of the plant material, taking the plant material and solvent in culture tubes, closing the tubes properly and dipping these tubes into liquid nitrogen at below-196 °C, melting the frozen material inside the tubes and collecting the liquid extract. The new method of plant extraction avoids exposing liquid nitrogen in open environment and thus avoids the drawbacks of the available methods of plant extraction using liquid nitrogen in open environment.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/37543001" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="044864ee70d407da732f7fe2852ae8d2" rel="nofollow" data-download="{"attachment_id":57517678,"asset_id":37543001,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/57517678/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3318863" href="https://ssjournals.academia.edu/ScholarScienceJournals">Scholar Science Journals</a><script data-card-contents-for-user="3318863" type="text/json">{"id":3318863,"first_name":"Scholar Science","last_name":"Journals","domain_name":"ssjournals","page_name":"ScholarScienceJournals","display_name":"Scholar Science Journals","profile_url":"https://ssjournals.academia.edu/ScholarScienceJournals?f_ri=145","photo":"https://0.academia-photos.com/3318863/1108470/20363147/s65_scholar_science.journals.png"}</script></span></span></li><li class="js-paper-rank-work_37543001 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="37543001"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 37543001, container: ".js-paper-rank-work_37543001", }); 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$(".js-view-count[data-work-id=37543001]").text(description); $(".js-view-count-work_37543001").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_37543001").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="37543001"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i> <a class="InlineList-item-text u-positionRelative">4</a> </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="140" href="https://www.academia.edu/Documents/in/Pharmacology">Pharmacology</a>, <script data-card-contents-for-ri="140" type="text/json">{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="145" href="https://www.academia.edu/Documents/in/Biochemistry">Biochemistry</a>, <script data-card-contents-for-ri="145" type="text/json">{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="656" href="https://www.academia.edu/Documents/in/Pharmacy">Pharmacy</a>, <script data-card-contents-for-ri="656" type="text/json">{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="3034676" href="https://www.academia.edu/Documents/in/International_Journal_of_Biomedical_and_Advance_Research">International Journal of Biomedical and Advance Research</a><script data-card-contents-for-ri="3034676" type="text/json">{"id":3034676,"name":"International Journal of Biomedical and Advance Research","url":"https://www.academia.edu/Documents/in/International_Journal_of_Biomedical_and_Advance_Research?f_ri=145","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=37543001]'), work: {"id":37543001,"title":"NEW METHOD FOR EXTRACTING PHYTOCONSTITUENTS FROM PLANTS","created_at":"2018-10-06T22:05:39.485-07:00","url":"https://www.academia.edu/37543001/NEW_METHOD_FOR_EXTRACTING_PHYTOCONSTITUENTS_FROM_PLANTS?f_ri=145","dom_id":"work_37543001","summary":"The present work is in the technical field of plant extraction. More particularly, the work relates to the extraction of medicinal plants using liquid nitrogen in a closed environment. The principal objective of this work is to provide a new method of plant extraction using liquid nitrogen which is simple, safe and less time consuming as compared to the existing open method of plant extraction using liquid nitrogen. The plant used for the study was Cynodon dactylon (Linn.) Pers. The new method includes the steps of size reduction of the plant material, taking the plant material and solvent in culture tubes, closing the tubes properly and dipping these tubes into liquid nitrogen at below-196 °C, melting the frozen material inside the tubes and collecting the liquid extract. The new method of plant extraction avoids exposing liquid nitrogen in open environment and thus avoids the drawbacks of the available methods of plant extraction using liquid nitrogen in open environment.","downloadable_attachments":[{"id":57517678,"asset_id":37543001,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3318863,"first_name":"Scholar Science","last_name":"Journals","domain_name":"ssjournals","page_name":"ScholarScienceJournals","display_name":"Scholar Science Journals","profile_url":"https://ssjournals.academia.edu/ScholarScienceJournals?f_ri=145","photo":"https://0.academia-photos.com/3318863/1108470/20363147/s65_scholar_science.journals.png"}],"research_interests":[{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology?f_ri=145","nofollow":false},{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false},{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy?f_ri=145","nofollow":false},{"id":3034676,"name":"International Journal of Biomedical and Advance Research","url":"https://www.academia.edu/Documents/in/International_Journal_of_Biomedical_and_Advance_Research?f_ri=145","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_36230624" data-work_id="36230624" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/36230624/RECOVERY_OF_THE_TRANSMEMBRANE_SYNTHESIS_PEPTIDE_CFTR_GENETIC_DEFECTS_delF508_NANOCRYSTALS_OF_HALLOUZITE">RECOVERY OF THE TRANSMEMBRANE SYNTHESIS PEPTIDE CFTR GENETIC DEFECTS delF508 NANOCRYSTALS OF HALLOUZITE</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Cystic fibrosis is the most common autosomal recessive potentially lethal hereditary disease. The disease is caused by mutations in the CFTR gene of the transmembrane peptide. CFTR, functioning as a cAMP-dependent chlorine channel,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_36230624" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Cystic fibrosis is the most common autosomal recessive potentially lethal hereditary disease. The disease is caused by mutations in the CFTR gene of the transmembrane peptide. CFTR, functioning as a cAMP-dependent chlorine channel, regulates chlorine and sodium channels, participates in water and ATP. As a result of a genetic defect, the secretion of the glands of external secretion thickens, its evacuation becomes more difficult, secondary changes occur in the organs.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/36230624" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8adcc6e9d6939d10f7bfaa40b1390255" rel="nofollow" data-download="{"attachment_id":56134075,"asset_id":36230624,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/56134075/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="2263402" href="https://kharkov-ua.academia.edu/BuriachenkoSemen">Buriachenko Semen</a><script data-card-contents-for-user="2263402" type="text/json">{"id":2263402,"first_name":"Buriachenko","last_name":"Semen","domain_name":"kharkov-ua","page_name":"BuriachenkoSemen","display_name":"Buriachenko Semen","profile_url":"https://kharkov-ua.academia.edu/BuriachenkoSemen?f_ri=145","photo":"https://0.academia-photos.com/2263402/720667/157952943/s65_buriachenko.semen.jpg"}</script></span></span></li><li class="js-paper-rank-work_36230624 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="36230624"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 36230624, container: ".js-paper-rank-work_36230624", }); });</script></li><li class="js-percentile-work_36230624 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 36230624; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_36230624"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_36230624 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="36230624"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 36230624; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=36230624]").text(description); $(".js-view-count-work_36230624").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_36230624").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="36230624"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i> <a class="InlineList-item-text u-positionRelative">6</a> </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="145" href="https://www.academia.edu/Documents/in/Biochemistry">Biochemistry</a>, <script data-card-contents-for-ri="145" type="text/json">{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="156" href="https://www.academia.edu/Documents/in/Genetics">Genetics</a>, <script data-card-contents-for-ri="156" type="text/json">{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="2513" href="https://www.academia.edu/Documents/in/Molecular_Biology">Molecular Biology</a>, <script data-card-contents-for-ri="2513" type="text/json">{"id":2513,"name":"Molecular Biology","url":"https://www.academia.edu/Documents/in/Molecular_Biology?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="7710" href="https://www.academia.edu/Documents/in/Biology">Biology</a><script data-card-contents-for-ri="7710" type="text/json">{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=145","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=36230624]'), work: {"id":36230624,"title":"RECOVERY OF THE TRANSMEMBRANE SYNTHESIS PEPTIDE CFTR GENETIC DEFECTS delF508 NANOCRYSTALS OF HALLOUZITE","created_at":"2018-03-22T11:04:17.543-07:00","url":"https://www.academia.edu/36230624/RECOVERY_OF_THE_TRANSMEMBRANE_SYNTHESIS_PEPTIDE_CFTR_GENETIC_DEFECTS_delF508_NANOCRYSTALS_OF_HALLOUZITE?f_ri=145","dom_id":"work_36230624","summary":"\nCystic fibrosis is the most common autosomal recessive potentially lethal hereditary disease. The disease is caused by mutations in the CFTR gene of the transmembrane peptide. CFTR, functioning as a cAMP-dependent chlorine channel, regulates chlorine and sodium channels, participates in water and ATP. As a result of a genetic defect, the secretion of the glands of external secretion thickens, its evacuation becomes more difficult, secondary changes occur in the organs.","downloadable_attachments":[{"id":56134075,"asset_id":36230624,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":2263402,"first_name":"Buriachenko","last_name":"Semen","domain_name":"kharkov-ua","page_name":"BuriachenkoSemen","display_name":"Buriachenko Semen","profile_url":"https://kharkov-ua.academia.edu/BuriachenkoSemen?f_ri=145","photo":"https://0.academia-photos.com/2263402/720667/157952943/s65_buriachenko.semen.jpg"}],"research_interests":[{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false},{"id":156,"name":"Genetics","url":"https://www.academia.edu/Documents/in/Genetics?f_ri=145","nofollow":false},{"id":2513,"name":"Molecular Biology","url":"https://www.academia.edu/Documents/in/Molecular_Biology?f_ri=145","nofollow":false},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=145","nofollow":false},{"id":19632,"name":"Molecular Genetics","url":"https://www.academia.edu/Documents/in/Molecular_Genetics?f_ri=145"},{"id":614079,"name":"Genetherapy","url":"https://www.academia.edu/Documents/in/Genetherapy?f_ri=145"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_36125165 coauthored" data-work_id="36125165" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/36125165/CARDIOPROTECTIVE_EFFECT_OF_GEMMOTHERAPEUTICALLY_TREATED_WITHANIA_SOMNIFERA_AGAINST_CHEMICALLY_INDUCED_MYOCARDIAL_INJURY">CARDIOPROTECTIVE EFFECT OF GEMMOTHERAPEUTICALLY TREATED WITHANIA SOMNIFERA AGAINST CHEMICALLY INDUCED MYOCARDIAL INJURY</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The present study was designed to evaluate the preventive and curative cardioprotective potential of native and gemmotherapeutically treated on the basis of biochemical, histopathological and antioxidant parameters in the salbutamol... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_36125165" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The present study was designed to evaluate the preventive and curative cardioprotective potential of native and gemmotherapeutically treated on the basis of biochemical, histopathological and antioxidant parameters in the salbutamol (albuterol) induced myocardial necrosis in rabbits. Gemmotherapy is a newly emerging way of treatment and no work so far has been done on evaluation of curative cardioprotective potential of Withania somnifera. Rabbits were divided into eight main groups: Normal, Ischemia, WS Gemmo-baseline, WS Native-baseline, WS Gemmo-preventive, WS Native-preventive, WS Gemmo-curative and WS Native-curative groups. Gemmo and native-baseline groups were treated with gemmo and native W. somnifera (50 mg/kg) for 20 days. Native and Gemmo-preventive groups were pre-treated with native and gemmotherapeutically treated W. somnifera at a dose 50 mg/kg for 3 weeks. On 20 th and 21 st day animals of all groups except normal and baseline groups were given Salbutamol (50mg/ kg), orally at an interval of 24 h. The Native-curative and Gemmo-curative groups were then treated with native and gemmotherapeutically treated W. somnifera at a dose 50 mg/ kg for 5 days, subsequent to the treatment with Salbutamol. Rabbits were subsequently sacrificed for gross pathological studies and hearts were removed for antioxidant assay. Administeration of Salbutamol significantly increased (p<0.05) the serum level of CK-MB, LDH, SGOT and SGPT in ischemia group as compared to Normal. However, pre-and post-treatment with Native and Gemmo extracts of W. somnifera significantly restored and reduced (p<0.05) the elevated serum levels of these cardiac markers. Also Native and Gemmo extracts of W. somnifera significantly increased (p<0.05) antioxidant enzymes; superoxide dismutase, catalase and glutathione peroxidase. No significant change was observed in the activity of cardiac enzymes in baseline groups. Protective actions of W. somnifera on heart have also been confirmed by gross pathology.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/36125165" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="425aff8b0904336b179262fb06a67b0b" rel="nofollow" data-download="{"attachment_id":56017641,"asset_id":36125165,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/56017641/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="78249997" href="https://uaf-pk.academia.edu/SamiaShoaib">Samia Shoaib</a><script data-card-contents-for-user="78249997" type="text/json">{"id":78249997,"first_name":"Samia","last_name":"Shoaib","domain_name":"uaf-pk","page_name":"SamiaShoaib","display_name":"Samia Shoaib","profile_url":"https://uaf-pk.academia.edu/SamiaShoaib?f_ri=145","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-36125165">+1</span><div class="hidden js-additional-users-36125165"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://uos.academia.edu/ZahoorUlHassanDogar">Zahoor-Ul-Hassan Dogar</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-36125165'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-36125165').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_36125165 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="36125165"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 36125165, container: ".js-paper-rank-work_36125165", }); });</script></li><li class="js-percentile-work_36125165 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 36125165; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_36125165"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_36125165 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="36125165"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 36125165; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=36125165]").text(description); $(".js-view-count-work_36125165").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_36125165").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="36125165"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i> <a class="InlineList-item-text u-positionRelative">4</a> </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="140" href="https://www.academia.edu/Documents/in/Pharmacology">Pharmacology</a>, <script data-card-contents-for-ri="140" type="text/json">{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="145" href="https://www.academia.edu/Documents/in/Biochemistry">Biochemistry</a>, <script data-card-contents-for-ri="145" type="text/json">{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="656" href="https://www.academia.edu/Documents/in/Pharmacy">Pharmacy</a>, <script data-card-contents-for-ri="656" type="text/json">{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy?f_ri=145","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4553" href="https://www.academia.edu/Documents/in/Toxicology">Toxicology</a><script data-card-contents-for-ri="4553" type="text/json">{"id":4553,"name":"Toxicology","url":"https://www.academia.edu/Documents/in/Toxicology?f_ri=145","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=36125165]'), work: {"id":36125165,"title":"CARDIOPROTECTIVE EFFECT OF GEMMOTHERAPEUTICALLY TREATED WITHANIA SOMNIFERA AGAINST CHEMICALLY INDUCED MYOCARDIAL INJURY","created_at":"2018-03-10T05:05:18.183-08:00","url":"https://www.academia.edu/36125165/CARDIOPROTECTIVE_EFFECT_OF_GEMMOTHERAPEUTICALLY_TREATED_WITHANIA_SOMNIFERA_AGAINST_CHEMICALLY_INDUCED_MYOCARDIAL_INJURY?f_ri=145","dom_id":"work_36125165","summary":"The present study was designed to evaluate the preventive and curative cardioprotective potential of native and gemmotherapeutically treated on the basis of biochemical, histopathological and antioxidant parameters in the salbutamol (albuterol) induced myocardial necrosis in rabbits. Gemmotherapy is a newly emerging way of treatment and no work so far has been done on evaluation of curative cardioprotective potential of Withania somnifera. Rabbits were divided into eight main groups: Normal, Ischemia, WS Gemmo-baseline, WS Native-baseline, WS Gemmo-preventive, WS Native-preventive, WS Gemmo-curative and WS Native-curative groups. Gemmo and native-baseline groups were treated with gemmo and native W. somnifera (50 mg/kg) for 20 days. Native and Gemmo-preventive groups were pre-treated with native and gemmotherapeutically treated W. somnifera at a dose 50 mg/kg for 3 weeks. On 20 th and 21 st day animals of all groups except normal and baseline groups were given Salbutamol (50mg/ kg), orally at an interval of 24 h. The Native-curative and Gemmo-curative groups were then treated with native and gemmotherapeutically treated W. somnifera at a dose 50 mg/ kg for 5 days, subsequent to the treatment with Salbutamol. Rabbits were subsequently sacrificed for gross pathological studies and hearts were removed for antioxidant assay. Administeration of Salbutamol significantly increased (p\u003c0.05) the serum level of CK-MB, LDH, SGOT and SGPT in ischemia group as compared to Normal. However, pre-and post-treatment with Native and Gemmo extracts of W. somnifera significantly restored and reduced (p\u003c0.05) the elevated serum levels of these cardiac markers. Also Native and Gemmo extracts of W. somnifera significantly increased (p\u003c0.05) antioxidant enzymes; superoxide dismutase, catalase and glutathione peroxidase. No significant change was observed in the activity of cardiac enzymes in baseline groups. Protective actions of W. somnifera on heart have also been confirmed by gross pathology.","downloadable_attachments":[{"id":56017641,"asset_id":36125165,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":78249997,"first_name":"Samia","last_name":"Shoaib","domain_name":"uaf-pk","page_name":"SamiaShoaib","display_name":"Samia Shoaib","profile_url":"https://uaf-pk.academia.edu/SamiaShoaib?f_ri=145","photo":"/images/s65_no_pic.png"},{"id":54700964,"first_name":"Zahoor-Ul-Hassan","last_name":"Dogar","domain_name":"uos","page_name":"ZahoorUlHassanDogar","display_name":"Zahoor-Ul-Hassan Dogar","profile_url":"https://uos.academia.edu/ZahoorUlHassanDogar?f_ri=145","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology?f_ri=145","nofollow":false},{"id":145,"name":"Biochemistry","url":"https://www.academia.edu/Documents/in/Biochemistry?f_ri=145","nofollow":false},{"id":656,"name":"Pharmacy","url":"https://www.academia.edu/Documents/in/Pharmacy?f_ri=145","nofollow":false},{"id":4553,"name":"Toxicology","url":"https://www.academia.edu/Documents/in/Toxicology?f_ri=145","nofollow":false}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_31671140 coauthored" data-work_id="31671140" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/31671140/Phytochemical_evaluation_of_the_ethanolic_extracts_of_Bauhinia_tomentosa_Linn_Root_">Phytochemical evaluation of the ethanolic extracts of Bauhinia tomentosa Linn. (Root)</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This research work carried about the phytochemical evaluation of the roots of Bauhinia tomentosa Linn. Belong to Fabaceae family. This study measures different physical and chemical characters, like-Ash Value, Extract, Chemical test which... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_31671140" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This research work carried about the phytochemical evaluation of the roots of Bauhinia tomentosa Linn. Belong to Fabaceae family. This study measures different physical and chemical characters, like-Ash Value, Extract, Chemical test which are useful in the Microscopical and Microscopical study of the root and different Pharmacological Activity of the plant such as Anti oxidant, Diuretic Activity and other more.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/31671140" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="75457c77235eee7f1bf997c7b548cad4" rel="nofollow" data-download="{"attachment_id":51992412,"asset_id":31671140,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/51992412/download_file?st=MTczMjc1NjAwMyw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="5960732" href="https://uptu.academia.edu/GirendraKumarGautam">Dr Girendra Gautam</a><script data-card-contents-for-user="5960732" type="text/json">{"id":5960732,"first_name":"Dr Girendra","last_name":"Gautam","domain_name":"uptu","page_name":"GirendraKumarGautam","display_name":"Dr Girendra Gautam","profile_url":"https://uptu.academia.edu/GirendraKumarGautam?f_ri=145","photo":"https://0.academia-photos.com/5960732/2531780/34725562/s65_dr_girendra.gautam.jpg"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-31671140">+1</span><div class="hidden js-additional-users-31671140"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/AKumar189">A. 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