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<ul id="toc-Signs_and_symptoms-sublist" class="vector-toc-list"> <li id="toc-Progression" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Progression"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.1</span> <span>Progression</span> </div> </a> <ul id="toc-Progression-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Transmission" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Transmission"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Transmission</span> </div> </a> <ul id="toc-Transmission-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Diagnosis_and_prognosis" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Diagnosis_and_prognosis"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Diagnosis and prognosis</span> </div> </a> <ul id="toc-Diagnosis_and_prognosis-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Prevention" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Prevention"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Prevention</span> </div> </a> <ul id="toc-Prevention-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Viral_structure" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Viral_structure"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Viral structure</span> </div> </a> <ul id="toc-Viral_structure-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Treatment" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Treatment"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Treatment</span> </div> </a> <button aria-controls="toc-Treatment-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Treatment subsection</span> </button> <ul id="toc-Treatment-sublist" class="vector-toc-list"> <li id="toc-Approved_US_treatment" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Approved_US_treatment"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.1</span> <span>Approved US treatment</span> </div> </a> <ul id="toc-Approved_US_treatment-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Approved_European_treatment" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Approved_European_treatment"> <div class="vector-toc-text"> <span class="vector-toc-numb">6.2</span> <span>Approved European treatment</span> </div> </a> <ul id="toc-Approved_European_treatment-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-History" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#History"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>History</span> </div> </a> <ul id="toc-History-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Comparison_with_feline_immunodeficiency_virus" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Comparison_with_feline_immunodeficiency_virus"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>Comparison with feline immunodeficiency virus</span> </div> </a> <ul id="toc-Comparison_with_feline_immunodeficiency_virus-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>See also</span> </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">10</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> <span class="vector-toc-numb">11</span> <span>External links</span> </div> </a> <ul id="toc-External_links-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><i>Feline leukemia virus</i></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 24 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-24" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">24 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%9B%D0%B5%D0%B2%D0%BA%D0%BE%D0%B7%D0%B0_%D0%BF%D1%80%D0%B8_%D0%BA%D0%BE%D1%82%D0%BA%D0%B8%D1%82%D0%B5" title="Левкоза при котките – Bulgarian" lang="bg" hreflang="bg" data-title="Левкоза при котките" data-language-autonym="Български" data-language-local-name="Bulgarian" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Virus_de_la_leuc%C3%A8mia_felina" title="Virus de la leucèmia felina – Catalan" lang="ca" hreflang="ca" data-title="Virus de la leucèmia felina" data-language-autonym="Català" data-language-local-name="Catalan" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Felines_Leuk%C3%A4mievirus" title="Felines Leukämievirus – German" lang="de" hreflang="de" data-title="Felines Leukämievirus" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Kasside_leukeemiaviirus" title="Kasside leukeemiaviirus – Estonian" lang="et" hreflang="et" data-title="Kasside leukeemiaviirus" data-language-autonym="Eesti" data-language-local-name="Estonian" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Virus_de_la_leucemia_felina" title="Virus de la leucemia felina – Spanish" lang="es" hreflang="es" data-title="Virus de la leucemia felina" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%88%DB%8C%D8%B1%D9%88%D8%B3_%D9%84%D9%88%D8%B3%D9%85%DB%8C_%DA%AF%D8%B1%D8%A8%D9%87%E2%80%8C%D8%B3%D8%A7%D9%86%D8%A7%D9%86" title="ویروس لوسمی گربه‌سانان – Persian" lang="fa" hreflang="fa" data-title="ویروس لوسمی گربه‌سانان" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Virus_leuc%C3%A9mog%C3%A8ne_f%C3%A9lin" title="Virus leucémogène félin – French" lang="fr" hreflang="fr" data-title="Virus leucémogène félin" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ga mw-list-item"><a href="https://ga.wikipedia.org/wiki/V%C3%ADreas_leoic%C3%A9ime_cat%C3%BAla" title="Víreas leoicéime catúla – Irish" lang="ga" hreflang="ga" data-title="Víreas leoicéime catúla" data-language-autonym="Gaeilge" data-language-local-name="Irish" class="interlanguage-link-target"><span>Gaeilge</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Virus_da_leucemia_felina" title="Virus da leucemia felina – Galician" lang="gl" hreflang="gl" data-title="Virus da leucemia felina" data-language-autonym="Galego" data-language-local-name="Galician" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EA%B3%A0%EC%96%91%EC%9D%B4_%EB%B0%B1%ED%98%88%EB%B3%91_%EB%B0%94%EC%9D%B4%EB%9F%AC%EC%8A%A4" title="고양이 백혈병 바이러스 – Korean" lang="ko" hreflang="ko" data-title="고양이 백혈병 바이러스" data-language-autonym="한국어" data-language-local-name="Korean" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%AB%E0%A5%87%E0%A4%B2%E0%A4%BF%E0%A4%A8_%E0%A4%B2%E0%A5%8D%E0%A4%AF%E0%A5%82%E0%A4%95%E0%A5%87%E0%A4%AE%E0%A4%BF%E0%A4%AF%E0%A4%BE_%E0%A4%B5%E0%A4%BE%E0%A4%87%E0%A4%B0%E0%A4%B8" title="फेलिन ल्यूकेमिया वाइरस – Hindi" lang="hi" hreflang="hi" data-title="फेलिन ल्यूकेमिया वाइरस" data-language-autonym="हिन्दी" data-language-local-name="Hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Feline_leukemia_virus" title="Feline leukemia virus – Indonesian" lang="id" hreflang="id" data-title="Feline leukemia virus" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Virus_della_leucemia_felina" title="Virus della leucemia felina – Italian" lang="it" hreflang="it" data-title="Virus della leucemia felina" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/Virus_leuchaemiae_felinae" title="Virus leuchaemiae felinae – Latin" lang="la" hreflang="la" data-title="Virus leuchaemiae felinae" data-language-autonym="Latina" data-language-local-name="Latin" class="interlanguage-link-target"><span>Latina</span></a></li><li class="interlanguage-link interwiki-lmo mw-list-item"><a href="https://lmo.wikipedia.org/wiki/Virus_de_la_leucemia_felina" title="Virus de la leucemia felina – Lombard" lang="lmo" hreflang="lmo" data-title="Virus de la leucemia felina" data-language-autonym="Lombard" data-language-local-name="Lombard" class="interlanguage-link-target"><span>Lombard</span></a></li><li class="interlanguage-link interwiki-arz mw-list-item"><a href="https://arz.wikipedia.org/wiki/%D9%81%D9%8A%D8%B1%D9%88%D8%B3_%D8%A7%D8%A8%D9%8A%D8%B6%D8%A7%D8%B6_%D8%A7%D9%84%D8%AF%D9%85_%D8%A7%D9%84%D9%87%D8%B1%D9%89_(%D9%83%D8%A7%D8%A6%D9%86)" title="فيروس ابيضاض الدم الهرى (كائن) – Egyptian Arabic" lang="arz" hreflang="arz" data-title="فيروس ابيضاض الدم الهرى (كائن)" data-language-autonym="مصرى" data-language-local-name="Egyptian Arabic" class="interlanguage-link-target"><span>مصرى</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Leukose" title="Leukose – Dutch" lang="nl" hreflang="nl" data-title="Leukose" data-language-autonym="Nederlands" data-language-local-name="Dutch" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Leucemia_felina" title="Leucemia felina – Portuguese" lang="pt" hreflang="pt" data-title="Leucemia felina" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%92%D0%B8%D1%80%D1%83%D1%81_%D0%BB%D0%B5%D0%B9%D0%BA%D0%BE%D0%B7%D0%B0_%D0%BA%D0%BE%D1%88%D0%B0%D1%87%D1%8C%D0%B8%D1%85" title="Вирус лейкоза кошачьих – Russian" lang="ru" hreflang="ru" data-title="Вирус лейкоза кошачьих" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Komplex_v%C3%ADrusovej_leuk%C3%A9mie_ma%C4%8Diek" title="Komplex vírusovej leukémie mačiek – Slovak" lang="sk" hreflang="sk" data-title="Komplex vírusovej leukémie mačiek" data-language-autonym="Slovenčina" data-language-local-name="Slovak" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Kissan_leukemiavirus" title="Kissan leukemiavirus – Finnish" lang="fi" hreflang="fi" data-title="Kissan leukemiavirus" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Kedi_l%C3%B6semi_vir%C3%BCs%C3%BC" title="Kedi lösemi virüsü – Turkish" lang="tr" hreflang="tr" data-title="Kedi lösemi virüsü" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Virus_b%E1%BA%A1ch_c%E1%BA%A7u_%E1%BB%9F_m%C3%A8o" title="Virus bạch cầu ở mèo – Vietnamese" lang="vi" hreflang="vi" data-title="Virus bạch cầu ở mèo" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E7%8C%AB%E7%99%BD%E8%A1%80%E7%97%85%E7%97%85%E6%AF%92" title="猫白血病病毒 – Chinese" lang="zh" hreflang="zh" data-title="猫白血病病毒" data-language-autonym="中文" data-language-local-name="Chinese" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a 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<div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Species of virus</div> <p class="mw-empty-elt"> </p> <table class="infobox biota" style="text-align: left; width: 200px; font-size: 100%"> <tbody><tr> <th colspan="2" style="color:inherit; text-align: center; background-color: rgb(250,250,190)"><i>Feline leukemia virus</i> </th></tr> <tr> <td colspan="2" style="text-align: center"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/File:Feline_leukemia_virus.JPG" class="mw-file-description"><img alt="Electron micrograph of "Feline leukemia virus"" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Feline_leukemia_virus.JPG/220px-Feline_leukemia_virus.JPG" decoding="async" width="220" height="146" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Feline_leukemia_virus.JPG/330px-Feline_leukemia_virus.JPG 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Feline_leukemia_virus.JPG/440px-Feline_leukemia_virus.JPG 2x" data-file-width="1808" data-file-height="1200" /></a></span> </td></tr> <tr> <td colspan="2" style="text-align: center; font-size: 88%"><a href="/wiki/Electron_micrograph" class="mw-redirect" title="Electron micrograph">Electron micrograph</a> of <i>Feline leukemia virus</i> </td></tr> <tr> <th colspan="2" style="color:inherit; min-width:15em; text-align: center; background-color: rgb(250,250,190)"><a href="/wiki/Virus_classification" title="Virus classification">Virus classification</a> <span class="plainlinks taxobox-edit-taxonomy skin-invert" style="font-size:smaller; float:right; padding-right:0.4em; margin-left:-3em;"><span typeof="mw:File"><a href="/wiki/Template:Taxonomy/Gammaretrovirus" title="Edit this classification"><img alt="Edit this classification" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr.svg/15px-OOjs_UI_icon_edit-ltr.svg.png" decoding="async" width="15" height="15" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr.svg/23px-OOjs_UI_icon_edit-ltr.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr.svg/30px-OOjs_UI_icon_edit-ltr.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span> </th></tr> <tr> <td>(unranked): </td> <td><a href="/wiki/Virus" title="Virus">Virus</a> </td></tr> <tr> <td><i>Realm</i>: </td> <td><a href="/wiki/Riboviria" title="Riboviria"><i>Riboviria</i></a> </td></tr> <tr> <td>Kingdom: </td> <td><a href="/wiki/Revtraviricetes" title="Revtraviricetes"><i>Pararnavirae</i></a> </td></tr> <tr> <td>Phylum: </td> <td><a href="/wiki/Revtraviricetes" title="Revtraviricetes"><i>Artverviricota</i></a> </td></tr> <tr> <td>Class: </td> <td><a href="/wiki/Revtraviricetes" title="Revtraviricetes"><i>Revtraviricetes</i></a> </td></tr> <tr> <td>Order: </td> <td><a href="/wiki/Ortervirales" title="Ortervirales"><i>Ortervirales</i></a> </td></tr> <tr> <td>Family: </td> <td><a href="/wiki/Retrovirus" title="Retrovirus"><i>Retroviridae</i></a> </td></tr> <tr> <td>Genus: </td> <td><a href="/wiki/Gammaretrovirus" title="Gammaretrovirus"><i>Gammaretrovirus</i></a> </td></tr> <tr> <td>Species: </td> <td><div style="display:inline" class="species"><i><b>Feline leukemia virus</b></i></div> </td></tr> <tr> <th colspan="2" style="color:inherit; text-align: center; background-color: rgb(250,250,190)"><a href="/wiki/Synonym_(taxonomy)" title="Synonym (taxonomy)">Synonyms</a><sup id="cite_ref-ICTV_1-0" class="reference"><a href="#cite_note-ICTV-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </th></tr> <tr> <td colspan="2" style="text-align: left"> <ul><li><i>Feline sarcoma and leukemia virus</i></li> <li><i>Feline sarcoma virus</i></li></ul> </td></tr> </tbody></table><style data-mw-deduplicate="TemplateStyles:r1238732961">@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox.biota tr{background:transparent!important}html.skin-theme-clientpref-night .mw-parser-output .infobox.biota img{background:transparent}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox.biota tr{background:transparent!important}html.skin-theme-clientpref-os .mw-parser-output .infobox.biota img{background:white}}.mw-parser-output .infobox.biota .taxobox-edit-taxonomy img{background:transparent!important}body.skin-vector .mw-parser-output table.biota.infobox{margin-top:0.5em}body.skin--responsive .mw-parser-output table.biota.infobox tr.taxonrow td{padding:2px 10px}</style> <p><b>Feline leukemia virus</b> (<b>FeLV</b>) is a <a href="/wiki/Retrovirus" title="Retrovirus">retrovirus</a> that infects <a href="/wiki/Cat" title="Cat">cats</a>. FeLV can be transmitted from infected cats when the transfer of saliva or nasal secretions is involved. If not defeated by the animal's <a href="/wiki/Immune_system" title="Immune system">immune system</a>, the virus weakens the cat's immune system, which can lead to diseases which can be lethal. Because FeLV is cat-to-cat contagious, FeLV+ cats should only live with other FeLV+ cats. </p><p>FeLV is categorized into four subgroups, A, B, C and T. An infected cat has a combination of FeLV-A and one or more of the other subgroups.<sup id="cite_ref-:3_2-0" class="reference"><a href="#cite_note-:3-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-:4_3-0" class="reference"><a href="#cite_note-:4-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Symptoms, prognosis and treatment are all affected by subgroup.<sup id="cite_ref-:3_2-1" class="reference"><a href="#cite_note-:3-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>FeLV+ cats often have a shorter lifespan, but can still live "normal", healthy lives.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Signs_and_symptoms">Signs and symptoms</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=1" title="Edit section: Signs and symptoms"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The signs and symptoms of infection with feline leukemia virus are quite varied and include <a href="/wiki/Loss_of_appetite" class="mw-redirect" title="Loss of appetite">loss of appetite</a>, poor coat condition, anisocoria (uneven pupils), infections of the skin, bladder, and respiratory tract, <a href="/wiki/Mouth_disease" class="mw-redirect" title="Mouth disease">oral disease</a>, <a href="/wiki/Seizures" class="mw-redirect" title="Seizures">seizures</a>, <a href="/wiki/Lymphadenopathy" title="Lymphadenopathy">lymphadenopathy</a> (swollen lymph nodes), <a href="/wiki/Skin_lesions" class="mw-redirect" title="Skin lesions">skin lesions</a>, <a href="/wiki/Fatigue_(medical)" class="mw-redirect" title="Fatigue (medical)">fatigue</a>, <a href="/wiki/Fever" title="Fever">fever</a>, <a href="/wiki/Weight_loss" title="Weight loss">weight loss</a>, <a href="/wiki/Stomatitis" title="Stomatitis">stomatitis</a>, <a href="/wiki/Gingivitis" title="Gingivitis">gingivitis</a>, litter box avoidance, <a href="/wiki/Pancytopenia" title="Pancytopenia">pancytopenia</a>, recurring bacterial and viral illnesses, <a href="/wiki/Anemia" title="Anemia">anemia</a>, <a href="/wiki/Diarrhea" title="Diarrhea">diarrhea</a> and <a href="/wiki/Jaundice" title="Jaundice">jaundice</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (November 2022)">citation needed</span></a></i>]</sup> </p><p>Asymptomatic carriers will show no signs of disease, often for many years.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (November 2022)">citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading3"><h3 id="Progression">Progression</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=2" title="Edit section: Progression"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The disease has a wide range of effects. The cat can fight off the infection and become totally immune, can become a healthy carrier that never gets sick itself but can infect other cats, or a mid-level case in which the cat has a compromised immune system.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (March 2009)">citation needed</span></a></i>]</sup> Nevertheless, the development of lymphomas is considered the final stage of the disease. Although it is thought that virus protein has to be present to induce lymphomas in cats, newer evidence shows that a high percentage of FeLV-Antigen negative lymphomas contain FeLV-DNA, indicating a "hit-and-run" mechanism of virus-induced tumor development.<sup id="cite_ref-Klopfleisch_5-0" class="reference"><a href="#cite_note-Klopfleisch-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>Once the virus has entered the cat, there are six stages to a FeLV infection<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (December 2012)">citation needed</span></a></i>]</sup>: </p> <ul><li>Stage One: The virus enters the cat, usually through the pharynx where it infects the epithelial cells and infects the tonsilar B-lymphocytes and macrophages. These white blood cells then filter down to the lymph nodes and begin to replicate.</li> <li>Stage Two: The virus enters the blood stream and begins to distribute throughout the body.</li> <li>Stage Three: The lymphoid system (which produces antibodies to attack infected and cancerous cells) becomes infected, with further distribution throughout the body.</li> <li>Stage Four: The main point in the infection, where the virus can take over the body's immune system and cause viremia. During this stage the hemolymphatic system and intestines become infected.</li></ul> <p>If the cat's immune system does not fight off the virus, then it progresses to:<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (November 2022)">citation needed</span></a></i>]</sup> </p> <ul><li>Stage Five: The <a href="/wiki/Bone_marrow" title="Bone marrow">bone marrow</a> becomes infected. At this point, the virus will stay with the cat for the rest of its life. In this phase, the virus replicates and is released four to seven days later in infected <a href="/wiki/Neutrophils" class="mw-redirect" title="Neutrophils">neutrophils</a>, and sometimes lymphocytes, <a href="/wiki/Monocytes" class="mw-redirect" title="Monocytes">monocytes</a>, and <a href="/wiki/Eosinophils" class="mw-redirect" title="Eosinophils">eosinophils</a> (all white blood cells formed in the bone marrow).</li> <li>Stage Six: The cat's body is overwhelmed by infection and mucosal and glandular epithelial cells (tissue that forms a thin protective layer on exposed bodily surfaces and forms the lining of internal cavities, ducts, and organs) become infected. The virus replicates in epithelial tissues including salivary glands, oropharynx, stomach, esophagus, intestines, trachea, nasopharynx, renal tubules, bladder, pancreas, alveolar ducts, and sebaceous ducts from the muzzle.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Transmission">Transmission</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=3" title="Edit section: Transmission"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/File:Outcomes_of_infection_with_Feline_Leukemia_Virus_(FeLV)_diagram.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c2/Outcomes_of_infection_with_Feline_Leukemia_Virus_%28FeLV%29_diagram.svg/220px-Outcomes_of_infection_with_Feline_Leukemia_Virus_%28FeLV%29_diagram.svg.png" decoding="async" width="220" height="185" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c2/Outcomes_of_infection_with_Feline_Leukemia_Virus_%28FeLV%29_diagram.svg/330px-Outcomes_of_infection_with_Feline_Leukemia_Virus_%28FeLV%29_diagram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c2/Outcomes_of_infection_with_Feline_Leukemia_Virus_%28FeLV%29_diagram.svg/440px-Outcomes_of_infection_with_Feline_Leukemia_Virus_%28FeLV%29_diagram.svg.png 2x" data-file-width="512" data-file-height="430" /></a><figcaption>Illustration of the potential outcomes following a cat's exposure to the FeLV infection</figcaption></figure> <p><a href="/wiki/Cat" title="Cat">Cats</a> infected with FeLV can serve as sources of infection of FeLV-A.<sup id="cite_ref-:4_3-1" class="reference"><a href="#cite_note-:4-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Cats can pass the virus between themselves through saliva and close contact, by biting another cat, and (rarely) through a litter box or food dish used by an infected cat.<sup id="cite_ref-:0_6-0" class="reference"><a href="#cite_note-:0-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>Once a cat has been infected with FeLV-A, additional mutated forms of the original FeLV-A virus may arise, as may FeLV subgroups B, C and T. </p><p>In addition to domestic cats, some other members of <a href="/wiki/Felidae" title="Felidae">Felidae</a> are now threatened by FeLV (e.g. <a href="/wiki/Lynx" title="Lynx">lynx</a> and <a href="/wiki/Florida_panther" title="Florida panther">Florida panther</a>).<sup id="cite_ref-:4_3-2" class="reference"><a href="#cite_note-:4-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Overwhelming <a href="/wiki/Epidemiology" title="Epidemiology">epidemiologic</a> evidence suggests FeLV is not transmissible to either humans<sup id="cite_ref-:3_2-2" class="reference"><a href="#cite_note-:3-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> or dogs.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>Approximately 0.5% of pet cats are persistently infected with FeLV, but many more pet cats (>35%) have specific <a href="/wiki/Immunoglobulin_G" title="Immunoglobulin G">IgG</a> antibodies which indicate prior exposure and subsequent development of <a href="/wiki/Immunity_(biology)" class="mw-redirect" title="Immunity (biology)">immunity</a> instead of <a href="/wiki/Infection" title="Infection">infection</a>. FeLV is highly infectious.<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p><p>Kittens can be born with it, having contracted it from their mother while <i>in utero</i>.<sup id="cite_ref-:0_6-1" class="reference"><a href="#cite_note-:0-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>Infection is far higher in city cats, stray or owned, than in rural cats: this is entirely due to the amount of contact the cats have with each other.<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Diagnosis_and_prognosis">Diagnosis and prognosis</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=4" title="Edit section: Diagnosis and prognosis"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Testing for FeLV is possible with <a href="/wiki/ELISA" title="ELISA">ELISA</a> tests that look for viral <a href="/wiki/Antigen" title="Antigen">antigens</a>, free particles found in the bloodstream. These ELISA tests use blood samples most often, but can also use saliva or eye secretions. The sample is added to a container or dish that contains the antibodies to the viral antigens. If the antigens are present in the sample, the antibodies will bind to them and an indicator on the test will change color. These give a definitive diagnosis, but it cannot differentiate between acute or persistent infections. Therefore, it is recommended that the cat be retested in three to four months after the positive result to determine if the virus has been cleared from the body. Diagnosis can also be made by reference lab testing, using an <a href="/wiki/Immunofluorescence" title="Immunofluorescence">immunofluorescence</a> (IFA) test. The IFA test uses a blood sample and will detect the virus once it is in the bone marrow by detecting the virus's presence in white blood cells. IFA testing will not give positive results for transient, primary infections - the infection must be persistent to get a positive result on this test. Other than ELISA and IFA testing, routine laboratory blood work may show changes that indicate infection but cannot be used as a definitive diagnosis. There may be blood cell count changes like <a href="/wiki/Leukopenia" title="Leukopenia">leukopenia</a>, decreased <a href="/wiki/Packed_cell_volume" class="mw-redirect" title="Packed cell volume">Packed Cell Volume (PCV)</a> and Total Protein (TP) levels due to <a href="/wiki/Anemia" title="Anemia">anemia</a>, hemoconcentration and hypoglycemia due to vomiting and diarrhea, electrolyte imbalance caused by dehydration and anorexia, and recurrent urinary tract infections.<sup id="cite_ref-:5_11-0" class="reference"><a href="#cite_note-:5-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p><p>Cats diagnosed as persistently infected by <a href="/wiki/ELISA" title="ELISA">ELISA</a> testing may die within a few months or may remain asymptomatic for longer; median survival time after diagnosis is 2.5 years.<sup id="cite_ref-:0_6-2" class="reference"><a href="#cite_note-:0-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>FeLV is categorized into four subgroups.<sup id="cite_ref-:3_2-3" class="reference"><a href="#cite_note-:3-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid21479142_12-0" class="reference"><a href="#cite_note-pmid21479142-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p> <ul><li>FeLV-A is responsible for the <a href="/wiki/Immunosuppression" title="Immunosuppression">immunosuppression</a> characteristic of the disease. The vast majority of cats with FeLV has FeLV-A.<sup id="cite_ref-:1_13-0" class="reference"><a href="#cite_note-:1-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> An exception was reported in 2013.<sup id="cite_ref-pmid23405366_14-0" class="reference"><a href="#cite_note-pmid23405366-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup></li> <li>FeLV-B causes an additional increase in the incidence of tumors and other abnormal tissue growths. About half of FeLV infected cats have FeLV-B.<sup id="cite_ref-:2_15-0" class="reference"><a href="#cite_note-:2-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> It forms by <a href="/wiki/Homologous_recombination" title="Homologous recombination">recombination</a> of FeLV-A and cat <a href="/wiki/Endogenous_retroviruses" class="mw-redirect" title="Endogenous retroviruses">endogenous FeLV</a> (enFeLV).<sup id="cite_ref-pmid21479142_12-1" class="reference"><a href="#cite_note-pmid21479142-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup></li> <li>FeLV-C causes severe anemia. Approximately 1% of FeLV infected cats have FeLV-C.<sup id="cite_ref-:1_13-1" class="reference"><a href="#cite_note-:1-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-:2_15-1" class="reference"><a href="#cite_note-:2-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> It forms by mutation of FeLV-A.<sup id="cite_ref-pmid21479142_12-2" class="reference"><a href="#cite_note-pmid21479142-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup></li> <li>FeLV-T leads to lymphoid depletion and immunodeficiency.<sup id="cite_ref-:3_2-4" class="reference"><a href="#cite_note-:3-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> It forms by mutation of FeLV-A.<sup id="cite_ref-pmid21479142_12-3" class="reference"><a href="#cite_note-pmid21479142-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup></li></ul> <p>The fatal diseases are <a href="/wiki/Leukemias" class="mw-redirect" title="Leukemias">leukemias</a>, <a href="/wiki/Lymphoma_in_animals" title="Lymphoma in animals">lymphomas</a>, and non-regenerative <a href="/wiki/Anemias" class="mw-redirect" title="Anemias">anemias</a>. Although there is no known cure for the virus infection, in 2006 the United States Department of Agriculture approved Lymphocyte T-Cell Immunomodulator as a treatment aid for FeLV (see <a class="mw-selflink-fragment" href="#Approved_US_treatment">Treatment</a>). </p><p>In Canada, one feline infected with progressive Feline Leukemia Virus Type C and its <a href="/wiki/Immune-mediated_hemolytic_anemia" class="mw-redirect" title="Immune-mediated hemolytic anemia">Immune-Mediated Hemolytic Anemia</a> complication has been successfully managed so far for over 6 months with the use of high-dose corticosteroids, broad-spectrum antibiotics to treat opportunistic and comorbid infections, antiviral medications, and immunomodulators such as cyclosporine after requiring multiple packed red blood cell transfusions to raise a critically low blood cell count. </p> <div class="mw-heading mw-heading2"><h2 id="Prevention">Prevention</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=5" title="Edit section: Prevention"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Three types of vaccines for FeLV are available: an <a href="/wiki/Immunologic_adjuvant" title="Immunologic adjuvant">adjuvanted</a> killed virus noninfectious vaccine, an adjuvanted subunit vaccine, and a nonadjuvanted canarypox virus-vectored recombinant infectious vaccine (<a href="/wiki/ATCvet" class="mw-redirect" title="ATCvet">ATCvet</a> code <a href="/wiki/ATCvet_code_QI06#QI06AA_Inactivated_viral_vaccines" title="ATCvet code QI06">QI066AA01</a> and various combination vaccines), though no currently available vaccine offers 100% protection from the virus.<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> Vaccination is recommended for high-risk cats: those that have access to the outdoors, feral cats, cats that do not have the virus but live with an infected cat, multicat households, and cats with an unknown status, such as cats in catteries and shelters.<sup id="cite_ref-:5_11-1" class="reference"><a href="#cite_note-:5-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p><p>Serious side effects have also been reported as a result of FeLV vaccination; in particular, a small percentage of cats who received the adjuvanted killed virus vaccine developed <a href="/wiki/Vaccine-associated_sarcoma" title="Vaccine-associated sarcoma">vaccine-associated sarcomas</a>, an aggressive tumour, at the injection site.<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> The development of sarcomas with the use of the old FeLV and other vaccines may be due to the inflammation caused by <a href="/wiki/Aluminium" title="Aluminium">aluminium</a> <a href="/wiki/Immunologic_adjuvant" title="Immunologic adjuvant">adjuvants</a> in the vaccines.<sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> </p><p><a href="/wiki/Merial" class="mw-redirect" title="Merial">Merial</a> produces a <a href="/wiki/Recombinant_DNA" title="Recombinant DNA">recombinant</a> vaccine consisting of <a href="/wiki/Canarypox" title="Canarypox">canarypox</a> virus carrying FeLV <a href="/wiki/Retrovirus#Genes" title="Retrovirus"><i>gag</i> and <i>env</i></a> genes (sold as PUREVAX FeLV in the US and Eurifel FeLV in Europe). This is thought to be safer than the old vaccine as it does not require an adjuvant to be effective. Although this is a live virus, it originates from a bird host and so does not replicate in mammals.<sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Viral_structure">Viral structure</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=6" title="Edit section: Viral structure"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><b>Feline leukemia virus (FeLV</b>) is an RNA virus in the subfamily <a href="/w/index.php?title=Oncovirinae&action=edit&redlink=1" class="new" title="Oncovirinae (page does not exist)">Oncovirinae</a> belonging to the <a href="/wiki/Retroviridae" class="mw-redirect" title="Retroviridae">Retroviridae</a> family. The <a href="/wiki/Virus" title="Virus">virus</a> comprises 5' and 3' LTRs and three genes: Gag (structural), Pol (enzymes) and Env (envelope and transmembrane); the total <a href="/wiki/Genome" title="Genome">genome</a> is about 9,600 <a href="/wiki/Base_pairs" class="mw-redirect" title="Base pairs">base pairs</a>.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (November 2022)">citation needed</span></a></i>]</sup> </p><p>See the entry on <a href="/wiki/Retrovirus" title="Retrovirus">retroviruses</a> for more details on the life cycle of FeLV.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (November 2022)">citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading2"><h2 id="Treatment">Treatment</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=7" title="Edit section: Treatment"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1251242444">.mw-parser-output .ambox{border:1px solid #a2a9b1;border-left:10px solid #36c;background-color:#fbfbfb;box-sizing:border-box}.mw-parser-output .ambox+link+.ambox,.mw-parser-output .ambox+link+style+.ambox,.mw-parser-output .ambox+link+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+style+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+link+.ambox{margin-top:-1px}html body.mediawiki .mw-parser-output .ambox.mbox-small-left{margin:4px 1em 4px 0;overflow:hidden;width:238px;border-collapse:collapse;font-size:88%;line-height:1.25em}.mw-parser-output .ambox-speedy{border-left:10px solid #b32424;background-color:#fee7e6}.mw-parser-output .ambox-delete{border-left:10px solid #b32424}.mw-parser-output .ambox-content{border-left:10px solid #f28500}.mw-parser-output .ambox-style{border-left:10px solid #fc3}.mw-parser-output .ambox-move{border-left:10px solid #9932cc}.mw-parser-output .ambox-protection{border-left:10px solid #a2a9b1}.mw-parser-output .ambox .mbox-text{border:none;padding:0.25em 0.5em;width:100%}.mw-parser-output .ambox .mbox-image{border:none;padding:2px 0 2px 0.5em;text-align:center}.mw-parser-output .ambox .mbox-imageright{border:none;padding:2px 0.5em 2px 0;text-align:center}.mw-parser-output .ambox .mbox-empty-cell{border:none;padding:0;width:1px}.mw-parser-output .ambox .mbox-image-div{width:52px}@media(min-width:720px){.mw-parser-output .ambox{margin:0 10%}}@media print{body.ns-0 .mw-parser-output .ambox{display:none!important}}</style><table class="box-Globalize plainlinks metadata ambox ambox-content ambox-globalize" role="presentation"><tbody><tr><td class="mbox-image"><div class="mbox-image-div"><span typeof="mw:File"><span><img alt="Globe icon." src="//upload.wikimedia.org/wikipedia/commons/thumb/b/bd/Ambox_globe_content.svg/48px-Ambox_globe_content.svg.png" decoding="async" width="48" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/bd/Ambox_globe_content.svg/73px-Ambox_globe_content.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/bd/Ambox_globe_content.svg/97px-Ambox_globe_content.svg.png 2x" data-file-width="350" data-file-height="290" /></span></span></div></td><td class="mbox-text"><div class="mbox-text-span">The examples and perspective in this article <b>deal primarily with the United States and do not represent a <a href="/wiki/Wikipedia:WikiProject_Countering_systemic_bias" title="Wikipedia:WikiProject Countering systemic bias">worldwide view</a> of the subject</b>.<span class="hide-when-compact"> You may <a class="external text" href="https://en.wikipedia.org/w/index.php?title=Feline_leukemia_virus&action=edit">improve this article</a>, discuss the issue on the <a href="/wiki/Talk:Feline_leukemia_virus" title="Talk:Feline leukemia virus">talk page</a>, or <a href="/wiki/Wikipedia:Article_wizard" title="Wikipedia:Article wizard">create a new article</a>, as appropriate.</span> <span class="date-container"><i>(<span class="date">July 2022</span>)</i></span><span class="hide-when-compact"><i> (<small><a href="/wiki/Help:Maintenance_template_removal" title="Help:Maintenance template removal">Learn how and when to remove this message</a></small>)</i></span></div></td></tr></tbody></table> <div class="mw-heading mw-heading3"><h3 id="Approved_US_treatment">Approved US treatment</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=8" title="Edit section: Approved US treatment"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In 2006, the <a href="/wiki/United_States_Department_of_Agriculture" title="United States Department of Agriculture">United States Department of Agriculture</a> issued a conditional license for a new treatment aid termed <a href="/wiki/Lymphocyte_T-Cell_Immunomodulator" class="mw-redirect" title="Lymphocyte T-Cell Immunomodulator">Lymphocyte T-Cell Immunomodulator</a> (LTCI).<sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> Lymphocyte T-Cell Immunomodulator is manufactured and distributed exclusively by T-Cyte Therapeutics, Inc.<sup id="cite_ref-Label_21-0" class="reference"><a href="#cite_note-Label-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> </p><p>Lymphocyte T-Cell Immunomodulator is intended as an aid in the treatment of cats infected with feline leukemia virus (FeLV) and/or <a href="/wiki/Feline_immunodeficiency_virus" title="Feline immunodeficiency virus">feline immunodeficiency virus</a> (FIV), and the associated symptoms of <a href="/wiki/Lymphocytopenia" title="Lymphocytopenia">lymphocytopenia</a>, <a href="/wiki/Opportunistic_infection" title="Opportunistic infection">opportunistic infection</a>, <a href="/wiki/Anemia" title="Anemia">anemia</a>, <a href="/wiki/Granulocytopenia" class="mw-redirect" title="Granulocytopenia">granulocytopenia</a>, or <a href="/wiki/Thrombocytopenia" title="Thrombocytopenia">thrombocytopenia</a>. The absence of any observed adverse events in several animal species suggests that the product has a very low toxicity profile. </p><p>Lymphocyte T-Cell Immunomodulator is a potent regulator of CD-4 <a href="/wiki/Lymphocyte" title="Lymphocyte">lymphocyte</a> production and function.<sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> It has been shown to increase lymphocyte numbers and <a href="/wiki/Interleukin_2" title="Interleukin 2">Interleukin 2</a> production in animals.<sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> </p><p>Lymphocyte T-Cell Immunomodulator is a single chain <a href="/wiki/Polypeptide" class="mw-redirect" title="Polypeptide">polypeptide</a>. It is a strongly cationic <a href="/wiki/Glycoprotein" title="Glycoprotein">glycoprotein</a>, and is purified with cation exchange resin. Purification of protein from bovine-derived <a href="/wiki/Stromal_cell" title="Stromal cell">stromal cell</a> supernatants produces a substantially homogeneous factor, free of extraneous materials. The bovine protein is homologous with other mammalian species and is a homogeneous 50 kDa glycoprotein with an isoelectric point of 6.5. The protein is prepared in a lyophilized 1 microgram dose. Reconstitution in sterile diluent produces a solution for subcutaneous injection.<sup id="cite_ref-Label_21-1" class="reference"><a href="#cite_note-Label-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Approved_European_treatment">Approved European treatment</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=9" title="Edit section: Approved European treatment"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Interferon-ω (omega) is sold in Europe at least under the name Virbagen Omega and manufactured by Virbac. When used in treatment of cats infected with FeLV in non-terminal clinical stages (over the age of 9 weeks) there have been substantial improvements in mortality rates; in non-anemic cats, mortality rate of 50% was reduced by approximately 20% following treatment.<sup id="cite_ref-24" class="reference"><a href="#cite_note-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="History">History</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=10" title="Edit section: History"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>FeLV was first described in cats in 1964.<sup id="cite_ref-Hartmann_2013_25-0" class="reference"><a href="#cite_note-Hartmann_2013-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> The disease was originally associated with leukemia; however, it was later realized that the initial signs are generally <a href="/wiki/Anemia" title="Anemia">anemia</a> and <a href="/wiki/Immunosuppression" title="Immunosuppression">immunosuppression</a>.<sup id="cite_ref-Hartmann_2013_25-1" class="reference"><a href="#cite_note-Hartmann_2013-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> The first diagnostic test became available in 1973, which led to a "test and elimination" regime, dramatically reducing the number of infected cats in the general population.<sup id="cite_ref-Louwerens_2005_26-0" class="reference"><a href="#cite_note-Louwerens_2005-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup> The first vaccine became available in 1986.<sup id="cite_ref-Louwerens_2005_26-1" class="reference"><a href="#cite_note-Louwerens_2005-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Comparison_with_feline_immunodeficiency_virus">Comparison with feline immunodeficiency virus</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=11" title="Edit section: Comparison with feline immunodeficiency virus"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>FeLV and <a href="/wiki/Feline_immunodeficiency_virus" title="Feline immunodeficiency virus">feline immunodeficiency virus</a> (FIV) are sometimes mistaken for one another, though the viruses differ in many ways. Although they are both in the same retroviral subfamily (Orthoretrovirinae), they are classified in different genera (FeLV is a gamma-retrovirus and FIV is a lentivirus like HIV-1). Their shapes are quite different: FeLV is more circular while FIV is elongated. The two viruses are also quite different genetically, and their protein coats differ in size and composition. Although many of the diseases caused by FeLV and FIV are similar, the specific ways in which they are caused also differ. Also, while the feline leukemia virus may cause symptomatic illness in an infected cat, an <a href="/wiki/FIV" class="mw-redirect" title="FIV">FIV</a> infected cat can remain completely asymptomatic its entire lifetime.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (January 2019)">citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=12" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Feline_foamy_virus" title="Feline foamy virus">Feline foamy virus</a> (FFV)</li> <li><a href="/wiki/Feline_immunodeficiency_virus" title="Feline immunodeficiency virus">Feline immunodeficiency virus</a> (FIV)</li> <li><a href="/wiki/Feline_vaccination" title="Feline vaccination">Feline vaccination</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Feline_leukemia_virus&action=edit&section=13" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>B. Zharkoy, A. Zolototrubov, D. Fedosov. "Intensity of free radical processes in limphocytes at BLV and FeLV". <i>Journal of Animal Science</i>. 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Elsevier Health Sciences. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9780323266215" title="Special:BookSources/9780323266215"><bdi>9780323266215</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Chapter+11%3A+Feline+leukemia+virus+infection&rft.btitle=Infectious+diseases+of+the+dog+and+cat&rft.edition=4&rft.pub=Elsevier+Health+Sciences&rft.date=2013&rft.isbn=9780323266215&rft.aulast=Hartmann&rft.aufirst=Katrin&rfr_id=info%3Asid%2Fen.wikipedia.org%3AFeline+leukemia+virus" class="Z3988"></span></span> </li> <li id="cite_note-Louwerens_2005-26"><span class="mw-cite-backlink">^ <a href="#cite_ref-Louwerens_2005_26-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Louwerens_2005_26-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLouwerensLondonPedersenLyons2005" class="citation journal cs1">Louwerens, M; London, CA; Pedersen, NC; Lyons, LA (2005). <a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1939-1676.2005.tb02703.x">"Feline lymphoma in the post-feline leukemia virus era"</a>. <i>Journal of Veterinary Internal Medicine</i>. <b>19</b> (3): 329–35. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1939-1676.2005.tb02703.x">10.1111/j.1939-1676.2005.tb02703.x</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15954547">15954547</a>.</cite><span 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rel="nofollow" class="external text" href="http://www.tcyte.com">Lymphocyte T-Cell Immunomodulator (LTCI)</a></li> <li><a rel="nofollow" class="external text" href="https://veterinarypartner.vin.com/default.aspx?pid=19239&id=4951934">Feline Leukemia Virus (FeLV) from Veterinary Partner</a></li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20190428185221/http://felineleukemia.org/">Feline leukemia Treatments and Support</a></li> <li><a rel="nofollow" class="external text" href="https://www.vet.cornell.edu/departments-centers-and-institutes/cornell-feline-health-center/health-information/feline-health-topics/feline-leukemia-virus">Feline Leukemia Virus from Cornell Feline Health Center</a></li> <li><a rel="nofollow" class="external text" href="https://www.petmd.com/cat/conditions/infectious-parasitic/c_ct_feline_leukemia">Feline Leukemia Virus Infection (FeLV) in Cats</a></li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20180522112006/https://www.fredhutch.org/en/news/spotlight/imports/feline-leukemia-virus-inhibits-thiamine-uptake--with-pathologica.html">Feline leukemia virus inhibits thiamine uptake, with pathological consequences</a></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul 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style="width:1%"><i><a href="/wiki/Retrovirus" title="Retrovirus">Retroviridae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Orthoretrovirinae" title="Orthoretrovirinae">Orthoretrovirinae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Alpharetrovirus" title="Alpharetrovirus">Alpharetrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Avian_sarcoma_leukosis_virus" title="Avian sarcoma leukosis virus">Avian sarcoma leukosis virus</a></li> <li><a href="/wiki/Rous_sarcoma_virus" title="Rous sarcoma virus">Rous sarcoma virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Betaretrovirus" title="Betaretrovirus">Betaretrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Mouse_mammary_tumor_virus" title="Mouse mammary tumor virus">Mouse mammary tumor virus</a></li> <li><a href="/wiki/Jaagsiekte_sheep_retrovirus" title="Jaagsiekte sheep retrovirus">Jaagsiekte sheep retrovirus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Deltaretrovirus" title="Deltaretrovirus">Deltaretrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Human_T-lymphotropic_virus" class="mw-redirect" title="Human T-lymphotropic virus">Human T-lymphotropic virus</a> (<a href="/wiki/Human_T-lymphotropic_virus_1" title="Human T-lymphotropic virus 1">HTLV-1</a></li> <li><a href="/wiki/Human_T-lymphotropic_virus_2" title="Human T-lymphotropic virus 2">HTLV-2</a>, 3, 4)</li> <li><a href="/wiki/Simian-T-lymphotropic_virus" class="mw-redirect" title="Simian-T-lymphotropic virus">Simian-T-lymphotropic virus</a> (types 1-4)</li> <li><a href="/wiki/Bovine_leukemia_virus" title="Bovine leukemia virus">Bovine leukemia virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Epsilonretrovirus" title="Epsilonretrovirus">Epsilonretrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Walleye_epidermal_hyperplasia_virus" title="Walleye epidermal hyperplasia virus">Walleye epidermal hyperplasia virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Gammaretrovirus" title="Gammaretrovirus">Gammaretrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Murine_leukemia_virus" title="Murine leukemia virus">Murine leukemia virus</a></li> <li><a href="/wiki/Abelson_murine_leukemia_virus" title="Abelson murine leukemia virus">Abelson murine leukemia virus</a></li> <li><a href="/wiki/Friend_virus" title="Friend virus">Friend virus</a></li> <li><a class="mw-selflink selflink">Feline leukemia virus</a></li> <li><a href="/wiki/Koala_retrovirus" title="Koala retrovirus">Koala retrovirus</a> (KoRV)</li> <li><a href="/wiki/Xenotropic_murine_leukemia_virus-related_virus" class="mw-redirect" title="Xenotropic murine leukemia virus-related virus">Xenotropic murine leukemia virus-related virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Lentivirus" title="Lentivirus">Lentivirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/HIV" title="HIV">HIV</a> (human immunodeficiency viruses)</li> <li><a href="/wiki/Simian_immunodeficiency_virus" title="Simian immunodeficiency virus">Simian immunodeficiency viruses</a> (SIV)</li> <li><a href="/wiki/Feline_immunodeficiency_virus" title="Feline immunodeficiency virus">Feline immunodeficiency virus</a> (FIV)</li> <li><a href="/wiki/Puma_lentivirus" title="Puma lentivirus">Puma lentivirus</a> (PLV)</li> <li><a href="/wiki/Equine_infectious_anemia" title="Equine infectious anemia">Equine infectious anemia virus</a> (EIAV)</li> <li><a href="/wiki/Bovine_immunodeficiency_virus" title="Bovine immunodeficiency virus">Bovine immunodeficiency virus</a> (BIV)</li> <li><a href="/wiki/Caprine_arthritis_encephalitis_virus" title="Caprine arthritis encephalitis virus">Caprine arthritis encephalitis virus</a></li> <li><a href="/wiki/Visna-maedi_virus" title="Visna-maedi virus">Visna-maedi virus</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Spumaretrovirinae" title="Spumaretrovirinae">Spumaretrovirinae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Bovispumavirus&action=edit&redlink=1" class="new" title="Bovispumavirus (page does not exist)">Bovispumavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Equispumavirus&action=edit&redlink=1" class="new" title="Equispumavirus (page does not exist)">Equispumavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Felispumavirus&action=edit&redlink=1" class="new" title="Felispumavirus (page does not exist)">Felispumavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Feline_foamy_virus" title="Feline foamy virus">Feline foamy virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Prosimiispumavirus&action=edit&redlink=1" class="new" title="Prosimiispumavirus (page does not exist)">Prosimiispumavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Simiispumavirus&action=edit&redlink=1" class="new" title="Simiispumavirus (page does not exist)">Simiispumavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Simian_foamy_virus" class="mw-redirect" title="Simian foamy virus">Simian foamy virus</a></li> <li><a href="/wiki/Human_foamy_virus" title="Human foamy virus">Human foamy virus</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">(<a href="/wiki/DsDNA-RT_virus" class="mw-redirect" title="DsDNA-RT virus">dsDNA-RT viruses</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="Caulimoviridae" scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Caulimoviridae" title="Caulimoviridae">Caulimoviridae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Badnavirus" title="Badnavirus">Badnavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Banana_streak_MY_virus" title="Banana streak MY virus">Banana streak MY virus</a></li> <li><a href="/wiki/Cacao_swollen_shoot_virus" title="Cacao swollen shoot virus">Cacao swollen shoot virus</a></li> <li><a href="/wiki/Kalanchoe_top-spotting_virus" title="Kalanchoe top-spotting virus">Kalanchoe top-spotting virus</a></li> <li><a href="/wiki/Rubus_yellow_net_virus" title="Rubus yellow net virus">Rubus yellow net virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Caulimovirus" title="Caulimovirus">Caulimovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Carnation_etched_ring_virus" title="Carnation etched ring virus">Carnation etched ring virus</a></li> <li><a href="/wiki/Cauliflower_mosaic_virus" title="Cauliflower mosaic virus">Cauliflower mosaic virus</a></li> <li><a href="/wiki/Strawberry_vein_banding_virus" title="Strawberry vein banding virus">Strawberry vein banding virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Cavemovirus" title="Cavemovirus">Cavemovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cassava_vein_mosaic_virus" title="Cassava vein mosaic virus">Cassava vein mosaic virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Dioscovirus&action=edit&redlink=1" class="new" title="Dioscovirus (page does not exist)">Dioscovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Petuvirus" title="Petuvirus">Petuvirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Rosadnavirus&action=edit&redlink=1" class="new" title="Rosadnavirus (page does not exist)">Rosadnavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Ruflodivirus&action=edit&redlink=1" class="new" title="Ruflodivirus (page does not exist)">Ruflodivirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Solendovirus" title="Solendovirus">Solendovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Soymovirus" title="Soymovirus">Soymovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Soybean_chlorotic_mottle_virus" title="Soybean chlorotic mottle virus">Soybean chlorotic mottle virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Tungrovirus" title="Tungrovirus">Tungrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Vaccinivirus&action=edit&redlink=1" class="new" title="Vaccinivirus (page does not exist)">Vaccinivirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Endogenous_retrovirus" title="Endogenous retrovirus">Endogenous</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/ERV-Fc" title="ERV-Fc">ERV-Fc</a></li> <li><a href="/wiki/Syncytin-1" title="Syncytin-1">ERVWE1</a></li> <li><a href="/wiki/HCP5" title="HCP5">HCP5</a></li> <li><a href="/wiki/Human_teratocarcinoma-derived_virus" class="mw-redirect" title="Human teratocarcinoma-derived virus">Human teratocarcinoma-derived virus</a></li> <li><a href="/wiki/Human_Endogenous_Retrovirus-W" class="mw-redirect" title="Human Endogenous Retrovirus-W">Human Endogenous Retrovirus-W</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"><style data-mw-deduplicate="TemplateStyles:r886047488">.mw-parser-output .nobold{font-weight:normal}</style></div><div role="navigation" class="navbox" aria-labelledby="Domestic_cats" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Domestic_cat" title="Template:Domestic cat"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Domestic_cat" title="Template talk:Domestic cat"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Domestic_cat" title="Special:EditPage/Template:Domestic cat"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Domestic_cats" style="font-size:114%;margin:0 4em"><a href="/wiki/Cat" title="Cat">Domestic cats</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Felinology" title="Felinology">Felinology</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cat_anatomy" title="Cat anatomy">Anatomy</a></li> <li><a href="/wiki/Cat_genetics" title="Cat genetics">Genetics</a></li> <li><a href="/wiki/Dwarf_cat" title="Dwarf cat">Dwarf cat</a></li> <li><a href="/wiki/Kitten" title="Kitten">Kitten</a></li> <li><a href="/wiki/Odd-eyed_cat" title="Odd-eyed cat">Odd-eyed cat</a></li> <li><a href="/wiki/Squitten" title="Squitten">Squitten</a></li> <li><span class="nobold"><a href="/wiki/Cat_coat_genetics" title="Cat coat genetics">Coat genetics</a></span></li> <li><a href="/wiki/Bicolor_cat" title="Bicolor cat">Bicolor cat</a></li> <li><a href="/wiki/Black_cat" title="Black cat">Black cat</a></li> <li><a href="/wiki/Calico_cat" title="Calico cat">Calico cat</a></li> <li><a href="/wiki/Tabby_cat" title="Tabby cat">Tabby cat</a></li> <li><a href="/wiki/Tortoiseshell_cat" title="Tortoiseshell cat">Tortoiseshell cat</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cat_health" title="Cat health">Health</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aging_in_cats" title="Aging in cats">Aging</a></li> <li><a href="/wiki/Onychectomy" title="Onychectomy">Declawing</a></li> <li><a href="/wiki/Cat_food" title="Cat food">Diet</a> <ul><li><a href="/wiki/Dental_health_diets_for_cats" title="Dental health diets for cats">dental health</a></li> <li><a href="/wiki/Senior_cat_diet" title="Senior cat diet">senior</a></li></ul></li> <li><a href="/wiki/Feline_vaccination" title="Feline vaccination">Vaccination</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cat_behavior" title="Cat behavior">Behavior</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cat%E2%80%93dog_relationship" title="Cat–dog relationship">Cat–dog relationship</a></li> <li><a href="/wiki/Cat_communication" title="Cat communication">Catfight</a></li> <li><a href="/wiki/Catnip" title="Catnip">Catnip</a> <ul><li><a href="/wiki/Valerian_(herb)" title="Valerian (herb)">valerian</a></li></ul></li> <li><a href="/wiki/Cat_communication" title="Cat communication">Communication</a> <ul><li><a href="/wiki/Meow" title="Meow">Meow</a></li> <li><a href="/wiki/Purr" title="Purr">Purr</a></li></ul></li> <li><a href="/wiki/Kneading_(cats)" title="Kneading (cats)">Kneading</a></li> <li><a href="/wiki/Cat_intelligence" title="Cat intelligence">Intelligence</a></li> <li><a href="/wiki/Cat_play_and_toys" title="Cat play and toys">Play and toys</a></li> <li><a href="/wiki/Cat_righting_reflex" title="Cat righting reflex">Righting reflex</a></li> <li><a href="/wiki/Cat_senses" title="Cat senses">Senses</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Human_interaction_with_cats" title="Human interaction with cats">Human–cat<br />interaction</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ailurophobia" title="Ailurophobia">Ailurophobia</a></li> <li><a href="/wiki/Cat_caf%C3%A9" title="Cat café">Cat cafés</a></li> <li><a href="/wiki/Category:Cat_killers" title="Category:Cat killers">Cat killers</a></li> <li><a href="/wiki/Cat_massage" title="Cat massage">Cat massage</a></li> <li><a href="/wiki/Cat_meat" title="Cat meat">Cat meat</a></li> <li><a href="/wiki/Cat-scratch_disease" title="Cat-scratch disease">Cat-scratch disease</a></li> <li><a href="/wiki/Cat_show" title="Cat show">Cat show</a></li> <li><a href="/wiki/Cats_in_ancient_Egypt" title="Cats in ancient Egypt">Cats in ancient Egypt</a></li> <li><a href="/wiki/Cultural_depictions_of_cats" title="Cultural depictions of cats">Cultural depictions</a> <ul><li><a href="/wiki/List_of_fictional_felines" title="List of fictional felines">fictional</a></li> <li><a href="/wiki/Cats_and_the_Internet" title="Cats and the Internet">Internet</a></li></ul></li> <li><a href="/wiki/Dog-like_cat" title="Dog-like cat">Dog-like cat</a></li> <li><a href="/wiki/Feral_cat" title="Feral cat">Feral cat</a></li> <li><a href="/wiki/Islam_and_cats" title="Islam and cats">Cats and Islam</a></li> <li><a href="/wiki/Lolcat" title="Lolcat">Lolcat</a></li> <li><a href="/wiki/National_Cat_Day" title="National Cat Day">National Cat Day</a></li> <li><a href="/wiki/Pet" title="Pet">Pet cat</a></li> <li><a href="/wiki/Working_cat" title="Working cat">Working cat</a> <ul><li><a href="/wiki/Bodega_cat" title="Bodega cat">Bodega cat</a></li> <li><a href="/wiki/Farm_cat" title="Farm cat">Farm cat</a></li> <li><a href="/wiki/Library_cat" title="Library cat">Library cat</a></li> <li><a href="/wiki/Ship%27s_cat" title="Ship's cat">Ship's cat</a></li></ul></li> <li><a href="/wiki/Feline_zoonosis" title="Feline zoonosis">Zoonosis</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cat_registry" title="Cat registry">Registries</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/American_Cat_Fanciers_Association" title="American Cat Fanciers Association">American Cat Fanciers Association</a></li> <li><a href="/wiki/Associazione_Nazionale_Felina_Italiana" title="Associazione Nazionale Felina Italiana">Associazione Nazionale Felina Italiana</a></li> <li><a href="/wiki/Canadian_Cat_Association" title="Canadian Cat Association">Canadian Cat Association</a></li> <li><a href="/wiki/Cat_Aficionado_Association" title="Cat Aficionado Association">Cat Aficionado Association</a></li> <li><a href="/wiki/Cat_Fanciers%27_Association" title="Cat Fanciers' Association">Cat Fanciers' Association</a></li> <li><a href="/wiki/F%C3%A9d%C3%A9ration_Internationale_F%C3%A9line" title="Fédération Internationale Féline">Fédération Internationale Féline</a></li> <li><a href="/wiki/Governing_Council_of_the_Cat_Fancy" title="Governing Council of the Cat Fancy">Governing Council of the Cat Fancy</a></li> <li><a href="/wiki/New_Zealand_Cat_Fancy" title="New Zealand Cat Fancy">New Zealand Cat Fancy</a></li> <li><a href="/wiki/Southern_Africa_Cat_Council" title="Southern Africa Cat Council">Southern Africa Cat Council</a></li> <li><a href="/wiki/The_International_Cat_Association" title="The International Cat Association">The International Cat Association</a></li> <li><a href="/wiki/World_Cat_Congress" title="World Cat Congress">World Cat Congress</a></li> <li><a href="/wiki/World_Cat_Federation" title="World Cat Federation">World Cat Federation</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Breeds<br />(<a href="/wiki/List_of_cat_breeds" title="List of cat breeds">full list</a>)<br />(<a href="/wiki/List_of_experimental_cat_breeds" title="List of experimental cat breeds">experimental</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Fully<br />domestic</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abyssinian_cat" title="Abyssinian cat">Abyssinian</a></li> <li><a href="/wiki/American_Curl" title="American Curl">American Curl</a></li> <li><a href="/wiki/American_Shorthair" title="American Shorthair">American Shorthair</a></li> <li><a href="/wiki/Balinese_cat" title="Balinese cat">Balinese</a></li> <li><a href="/wiki/Brazilian_Shorthair" title="Brazilian Shorthair">Brazilian Shorthair</a></li> <li><a href="/wiki/British_Shorthair" title="British Shorthair">British Shorthair</a></li> <li><a href="/wiki/Birman" title="Birman">Birman</a></li> <li><a href="/wiki/Bombay_cat" title="Bombay cat">Bombay</a></li> <li><a href="/wiki/Burmese_cat" title="Burmese cat">Burmese</a></li> <li><a href="/wiki/Burmilla" title="Burmilla">Burmilla</a></li> <li><a href="/wiki/California_Spangled" title="California Spangled">California Spangled</a></li> <li><a href="/wiki/Chartreux" title="Chartreux">Chartreux</a></li> <li><a href="/wiki/Dragon_Li" title="Dragon Li">Chinese Li Hua</a></li> <li><a href="/wiki/Colorpoint_Shorthair" title="Colorpoint Shorthair">Colorpoint Shorthair</a></li> <li><a href="/wiki/Cornish_Rex" title="Cornish Rex">Cornish Rex</a></li> <li><a href="/wiki/Cymric_cat" title="Cymric cat">Cymric</a></li> <li><a href="/wiki/Devon_Rex" title="Devon Rex">Devon Rex</a></li> <li><a href="/wiki/Donskoy_cat" title="Donskoy cat">Donskoy</a></li> <li><a href="/wiki/Egyptian_Mau" title="Egyptian Mau">Egyptian Mau</a></li> <li><a href="/wiki/European_Shorthair" title="European Shorthair">European Shorthair</a></li> <li><a href="/wiki/Exotic_Shorthair" title="Exotic Shorthair">Exotic Shorthair</a></li> <li><a href="/wiki/Foldex_cat" title="Foldex cat">Foldex</a></li> <li><a href="/wiki/German_Rex" title="German Rex">German Rex</a></li> <li><a href="/wiki/Himalayan_cat" title="Himalayan cat">Himalayan</a></li> <li><a href="/wiki/Japanese_Bobtail" title="Japanese Bobtail">Japanese Bobtail</a></li> <li><a href="/wiki/Javanese_cat" title="Javanese cat">Javanese</a></li> <li><a href="/wiki/Khao_Manee" title="Khao Manee">Khao Manee</a></li> <li><a href="/wiki/Korat" title="Korat">Korat</a></li> <li><a href="/wiki/Kurilian_Bobtail" title="Kurilian Bobtail">Kurilian Bobtail</a></li> <li><a href="/wiki/Lykoi" title="Lykoi">Lykoi</a></li> <li><a href="/wiki/Maine_Coon" title="Maine Coon">Maine Coon</a></li> <li><a href="/wiki/Manx_cat" title="Manx cat">Manx</a></li> <li><a href="/wiki/Munchkin_cat" title="Munchkin cat">Munchkin</a></li> <li><a href="/wiki/Neva_Masquerade" title="Neva Masquerade">Neva Masquerade</a></li> <li><a href="/wiki/Norwegian_Forest_cat" class="mw-redirect" title="Norwegian Forest cat">Norwegian Forest</a></li> <li><a href="/wiki/Ocicat" title="Ocicat">Ocicat</a></li> <li><a href="/wiki/Ojos_Azules" title="Ojos Azules">Ojos Azules</a></li> <li><a href="/wiki/Oriental_Shorthair" title="Oriental Shorthair">Oriental Shorthair</a></li> <li><a href="/wiki/Persian_cat" title="Persian cat">Persian</a></li> <li><a href="/wiki/Peterbald" title="Peterbald">Peterbald</a></li> <li><a href="/wiki/Pixie-bob" title="Pixie-bob">Pixie-bob</a></li> <li><a href="/wiki/Ragdoll" title="Ragdoll">Ragdoll</a></li> <li><a href="/wiki/Ragamuffin_cat" title="Ragamuffin cat">Ragamuffin</a></li> <li><a href="/wiki/Russian_Blue" title="Russian Blue">Russian Blue</a></li> <li><a href="/wiki/Scottish_Fold" title="Scottish Fold">Scottish Fold</a></li> <li><a href="/wiki/Selkirk_Rex" title="Selkirk Rex">Selkirk Rex</a></li> <li><a href="/wiki/Siamese_cat" title="Siamese cat">Siamese</a></li> <li><a href="/wiki/Siberian_cat" title="Siberian cat">Siberian</a></li> <li><a href="/wiki/Singapura_cat" title="Singapura cat">Singapura</a></li> <li><a href="/wiki/Snowshoe_cat" title="Snowshoe cat">Snowshoe</a></li> <li><a href="/wiki/Somali_cat" title="Somali cat">Somali</a></li> <li><a href="/wiki/Sphynx_cat" title="Sphynx cat">Sphynx</a></li> <li><a href="/wiki/Thai_cat" title="Thai cat">Thai</a></li> <li><a href="/wiki/Traditional_Persian" title="Traditional Persian">Traditional Persian</a></li> <li><a href="/wiki/Tonkinese_cat" title="Tonkinese cat">Tonkinese</a></li> <li><a href="/wiki/Toyger" title="Toyger">Toyger</a></li> <li><a href="/wiki/Turkish_Angora" title="Turkish Angora">Turkish Angora</a></li> <li><a href="/wiki/Turkish_Van" title="Turkish Van">Turkish Van</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Hybrid</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bengal_cat" title="Bengal cat">Bengal</a></li> <li><a href="/wiki/Chausie" title="Chausie">Chausie</a></li> <li><a href="/wiki/Highlander_cat" title="Highlander cat">Highlander</a></li> <li><a href="/wiki/Savannah_cat" title="Savannah cat">Savannah</a></li> <li><a href="/wiki/Serengeti_cat" title="Serengeti cat">Serengeti</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Landrace" title="Landrace">Landraces</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aegean_cat" title="Aegean cat">Aegean</a></li> <li><a href="/wiki/Cyprus_cat" title="Cyprus cat">Cyprus</a></li> <li><a href="/wiki/Kellas_cat" title="Kellas cat">Kellas</a></li> <li><a href="/wiki/Sokoke" title="Sokoke">Sokoke</a></li> <li><a href="/wiki/Van_cat" title="Van cat">Van</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/List_of_feline_diseases" title="List of feline diseases">Diseases and<br />disorders</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Feline_acne" title="Feline acne">Acne</a></li> <li><a href="/wiki/Feline_asthma" title="Feline asthma">Asthma</a></li> <li><a href="/wiki/Feline_calicivirus" title="Feline calicivirus">Calicivirus</a></li> <li><a href="/wiki/Congenital_sensorineural_deafness_in_cats" title="Congenital sensorineural deafness in cats">Congenital sensorineural deafness</a></li> <li><a href="/wiki/Feline_corneal_sequestrum" title="Feline corneal sequestrum">Feline corneal sequestrum</a></li> <li><a href="/wiki/Cat_flea" title="Cat flea">Flea</a></li> <li><a href="/wiki/Coccidia" title="Coccidia">Coccidia</a></li> <li><a href="/wiki/Dirofilaria_immitis" title="Dirofilaria immitis">Heartworm</a></li> <li><a href="/wiki/Feline_hepatic_lipidosis" title="Feline hepatic lipidosis">Hepatic lipidosis</a></li> <li><a href="/wiki/Hypertrophic_cardiomyopathy#Related_disorders" title="Hypertrophic cardiomyopathy">Hypertrophic cardiomyopathy</a></li> <li><a href="/wiki/Feline_immunodeficiency_virus" title="Feline immunodeficiency virus">Immunodeficiency virus</a></li> <li><a href="/wiki/Feline_infectious_peritonitis" title="Feline infectious peritonitis">Infectious peritonitis</a></li> <li><a class="mw-selflink selflink">Leukemia virus</a></li> <li><a href="/wiki/Feline_lower_urinary_tract_disease" title="Feline lower urinary tract disease">Lower urinary tract disease</a></li> <li><a href="/wiki/Carnivore_protoparvovirus_1" title="Carnivore protoparvovirus 1">Panleukopenia</a></li> <li><a href="/wiki/Giardiasis" title="Giardiasis">Giardiasis</a></li> <li><a href="/wiki/Polydactyl_cat" title="Polydactyl cat">Polydactyly</a></li> <li><a href="/wiki/Rabies_in_animals" title="Rabies in animals">Rabies</a></li> <li><a href="/wiki/Dermatophytosis" title="Dermatophytosis">Ringworm</a></li> <li><a href="/wiki/Tritrichomonas_foetus" title="Tritrichomonas foetus">Tritrichomonas foetus</a></li> <li><a href="/wiki/Toxocara_cati" title="Toxocara cati">Roundworm</a></li> <li><a href="/wiki/Cat_skin_disorders" title="Cat skin disorders">Skin disorders</a></li> <li><a href="/wiki/Tick" title="Tick">Tick</a></li> <li><a href="/wiki/Toxoplasmosis" title="Toxoplasmosis">Toxoplasmosis</a></li> <li><a href="/wiki/Feline_viral_rhinotracheitis" title="Feline viral rhinotracheitis">Viral rhinotracheitis</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Category:Cats_by_country" title="Category:Cats by country">Cats by country</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cats_in_Australia" title="Cats in Australia">Australia</a></li> <li><a href="/wiki/Category:Cats_in_Canada" title="Category:Cats in Canada">Canada</a></li> <li><a href="/wiki/Category:Cats_in_Japan" title="Category:Cats in Japan">Japan</a></li> <li><a href="/wiki/Cats_in_New_Zealand" title="Cats in New Zealand">New Zealand</a></li> <li><a href="/wiki/Category:Cats_in_the_United_Kingdom" title="Category:Cats in the United Kingdom">United Kingdom</a></li> <li><a href="/wiki/Cats_in_the_United_States" title="Cats in the United States">United States</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Related</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/List_of_individual_cats" title="List of individual cats">List of individual cats</a></li> <li><a href="/wiki/List_of_longest-living_cats" title="List of longest-living cats">List of longest-living cats</a></li> <li><a href="/wiki/Category:Cat_folklore" title="Category:Cat folklore">Cats in folklore</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="font-weight:bold;"><div> <ul><li><span class="noviewer" typeof="mw:File"><span title="Category"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/16px-Symbol_category_class.svg.png" decoding="async" width="16" height="16" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/23px-Symbol_category_class.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/96/Symbol_category_class.svg/31px-Symbol_category_class.svg.png 2x" data-file-width="180" data-file-height="185" /></span></span> <a href="/wiki/Category:Cats" title="Category:Cats">Category</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link 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title="wikidata:Q769471">Q769471</a></span></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Wikispecies" title="Wikispecies">Wikispecies</a>: <span class="uid"><span class="external"><a href="https://species.wikimedia.org/wiki/Feline_leukemia_virus" class="extiw" title="wikispecies:Feline leukemia virus">Feline leukemia virus</a></span></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Catalogue_of_Life" title="Catalogue of Life">CoL</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://www.catalogueoflife.org/data/taxon/6HR4B">6HR4B</a></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Encyclopedia_of_Life" title="Encyclopedia of Life">EoL</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://eol.org/pages/540026">540026</a></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Global_Biodiversity_Information_Facility" title="Global Biodiversity Information Facility">GBIF</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://www.gbif.org/species/10105910">10105910</a></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Interim_Register_of_Marine_and_Nonmarine_Genera" title="Interim Register of Marine and Nonmarine Genera">IRMNG</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://www.irmng.org/aphia.php?p=taxdetails&id=11459799">11459799</a></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/National_Center_for_Biotechnology_Information" title="National Center for Biotechnology Information">NCBI</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=11768">11768</a></span></span></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link 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