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Ensure Safety & Compliance"}}]}, {"@context":"https:\/\/schema.org\/","@type":"Article","@id":"https:\/\/microbe-investigations.com\/disinfectant-validation\/#Article","url":"https:\/\/microbe-investigations.com\/disinfectant-validation\/","inLanguage":"en-US","mainEntityOfPage":"https:\/\/microbe-investigations.com\/disinfectant-validation\/","headline":"What is Disinfectant Validation? Ensure Safety & Compliance","description":"Discover the importance of disinfectant validation in ensuring lab safety and compliance. Our experts offer thorough validation and testing services for maximum efficacy.","articleBody":"In industries like healthcare, pharmaceuticals and biotechnology, maintaining high levels of cleanliness and hygiene is crucial for preventing infections and contamination. Disinfectant validation is the process that ensures disinfectants used in these environments are effective against a wide spectrum of microorganisms, including bacteria, viruses, fungi and spores. Disinfectant validation ensures that cleaning and disinfection protocols are both reliable and effective in reducing contamination risks.  This article explores the key aspects of disinfectant validation, including the relevant terminology, regulatory framework, key components of validation reports and challenges associated with validation. Definitions and terminology for antimicrobial products In order to briefly present the details of disinfectant validation it is necessary to understand the terminology concerning antimicrobial products. Disinfectants: Chemical agents which destroy or inactivate microorganisms on inanimate objects and surfaces. Disinfectants act against bacteria, viruses and fungi but may not necessarily destroy bacterial spores. Sporicides: One of the subset of disinfectants formulated specifically to kill bacterial spores since they tend to be more resistant to the action of chemical agents than other types of microorganisms. Antiseptics: Similar to disinfectants, except these products work on living tissue such as human skin to reduce the number of microorganisms. Sanitizers: Agents used to reduce the number of microorganisms to a safe number. Typically applied in food-preparation environments and community health environments. All these antimicrobial agents play an important role in preventing and controlling infections. Their approval ensures they are applied appropriately within their intended environment. What are disinfectants? Disinfectants are chemical agents specifically designed to inactivate or destroy microorganisms on surfaces and thus they provide a crucial service in maintaining a sterile environment for healthcare, laboratories and manufacturing. Disinfectants differ depending on their spectrum of action. Broad-spectrum disinfectants act against a wide spectrum of microorganisms, to relatively narrow-spectrum and specialized disinfectant formulation that targets either bacteria, viruses, or fungi. There are several types of disinfectants, including: Alcohol-based disinfectants: These work fast but are volatile and are often used for medical instruments. Phenolic disinfectants: Effective against most pathogens which are widely used in health-care facilities. Quaternary ammonium compounds: Effective against many pathogens, commonly used in healthcare settings. Chlorine compounds: Highly effective but corrosive to surfaces and degrade organic materials. What are sporicides? Sporicides are chemical disinfectants specifically designed to inactivate spores, which are the most resistant forms of microbes. They are particularly applied in sterility demanding situations-for example, in pharmaceuticals, cleanrooms and hospital use. Bacterial spores such as Clostridium difficile and Bacillus anthracis survive physical and chemical stresses and disinfectants lethal to other types of microbes. Thus, sporicides form one of the pillars upon which a disinfection strategy is built in high-risk situations. Regulatory framework for disinfectant validation protocol The regulatory framework governing disinfectant validation is comprehensive, involving guidelines and standards from various national and international bodies. In the pharmaceutical industry, disinfectant validation is typically required by regulatory bodies such as the FDA (Food and Drug Administration) in the United States and EMA (European Medicines Agency) in Europe. These agencies require thorough validation to ensure that disinfectants are effective and appropriate for use in cleanrooms, sterile production environments, and healthcare settings. ISO standards also play a crucial role in the regulatory framework. For example, ISO 14698 provides guidance on biocontamination control. The regulatory framework ensures that disinfectants used in critical environments are validated based on their ability to eliminate specific microbial contaminants. Efficacy testing of disinfectants Efficacy testing of disinfectants is the process of determining the efficiency of a disinfectant to remove or reduce microbial populations on surfaces. It is conducted under laboratory conditions and, in some cases, under real-time environments to simulate the practical applications of the disinfectant. The log reduction method primarily used for quantifying the efficacy is one, wherein higher log reduction means greater efficiency in killing the targeted microorganisms. This testing usually involves: Surface testing: Ability of a disinfectant to clean various surfaces, for example, stainless steel, glass, or plastics. Contact time: Determining the amount of time the disinfectant needs to remain on a surface to be effective. Environmental testing: Testing the disinfectant under real-world conditions, such as in cleanrooms or healthcare environments. Key components of a disinfectant validation report A validation report of a disinfectant is crucial as it captures all aspects of the process, thus making the process transparent and traceable. The report contains details about:  Objective: Clear statement of the goal. Ensuring that the disinfectant remains effective against the microorganisms of interest in the environment of use. Methodology: Includes detailed description of the testing methods used, involving the selection of microorganisms, test surfaces and concentrations of the disinfectant and times of exposure. Test microorganisms: Selection of representative microorganisms, including bacteria, fungi, viruses and spores, which are relevant to the environment being disinfected. Results: Complete data set documenting efficacy of the disinfectant. This entails log reduction values for microbial counts before and after disinfection. Conclusions: Summary of the results, confirming whether the disinfectant met the efficacy requirements. Recommendations: Recommendations for any change in the cleaning protocol based on validation results. Registration of antimicrobial products for validation of disinfectants The registration is important for the registration of antimicrobial products because the disinfectants need to be approved in terms of safety and effectiveness dictated by the standards. Registration in the United States is maintained with the Environmental Protection Agency, while in Europe, it falls under the Biocidal Products Regulation (BPR). Agencies require significant data to prove that the product is safe for its intended use and effective against relevant microorganisms. Registration prerequisites include a dataset of efficacy obtained from validation studies. Such studies are considered to be the basis on which claims about the efficacy of the disinfectant against specific microbial contaminants are made. Challenges in disinfectant validation Disinfectant validation comes with several challenges, including: Environmental variability: The practical application of disinfectants occurs at specific temperatures, level of moisture or even the types of surfaces affecting their effectiveness. Complex microbial communities: Some environments may have biofilms or a diversity of microorganisms that are more resistant to disinfectants, complicating validation in some environments. Surface compatibility: The same disinfectant can respond differently to various surfaces and may cause corrosion or degradation. Consequently, compatibility with surfaces is important. Importance of disinfectant validation Disinfectant validation is important because it ensures the cleaning protocols are effective and safe in areas where contamination poses a great danger, such as healthcare facilities, pharmaceutical manufacturing, or food processing plants. Proper validation protects the products from cross-contamination, healthcare-acquired infections and product recalls, among other issues. Eventually meeting regulatory requirements. Conclusion The validation of disinfectants is an important document for ensuring the effectiveness and safety of the disinfectant in its application within high-precaution environments. The process ensures disinfectants are frequently effective in real-life situations. Disinfectant companies ensuring compliance according to high regulatory standards should invest in professional testing services. For disinfectant manufacturers looking to validate their products, Microbe Investigations Switzerland (MIS) offers expert validation and testing services that ensure compliance, efficacy and safety. Contact MIS today to learn more about how our validation services can elevate your product\u2019s quality and regulatory compliance. FAQs 1. Why is disinfectant validation important? Disinfectant validation provides evidence that disinfectants eliminate pathogens under controlled conditions while eliminating microbes and maintaining regulatory compliance. 2. How is disinfectant validation performed? Disinfectant validation is carried out by testing the product's efficacy on a range of microbial strains on surfaces pertinent to where it is going to be applied. 3. What is the difference between disinfectant validation and disinfectant efficacy testing? Disinfectant validation tests its efficacy in a specific environment, whereas effectiveness tests its general antimicrobial capacity. 4. What is the cost of disinfectant validation? The cost of disinfectant validation is set by the testing complexity and number of strains and type of surfaces. 5. How often should disinfectant validation be performed? Validation of disinfectants should be done on a periodic basis. 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data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <span>Cosmetics</span> </div> </div> <div class="elementor-element elementor-element-5abab8bb elementor-widget elementor-widget-heading" data-id="5abab8bb" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default"><a href="https://microbe-investigations.com/what-is-cosmetogenomics/">Cosmetogenomics: Revolutionizing Personalized Skincare</a></h2> </div> </div> <div class="elementor-element elementor-element-50fd7ed1 elementor-view-default elementor-widget elementor-widget-icon" data-id="50fd7ed1" data-element_type="widget" data-widget_type="icon.default"> <div class="elementor-widget-container"> <div class="elementor-icon-wrapper"> <a class="elementor-icon" href="https://microbe-investigations.com/what-is-cosmetogenomics/"> <svg xmlns="http://www.w3.org/2000/svg" width="29" height="29" viewBox="0 0 29 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mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18220' id='mega-menu-item-18220'><a class="mega-menu-link" href="/entomology-testing-services/" aria-expanded="false">Entomology (Agri, Homecare)<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18221' id='mega-menu-item-18221'><a class="mega-menu-link" href="#" aria-expanded="false">Laboratory tests<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18222' id='mega-menu-item-18222'><a class="mega-menu-link" href="/arm-in-cage-test/">Arm In Cage Room Test</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18223' id='mega-menu-item-18223'><a class="mega-menu-link" href="/room-test/">Room Test</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18416' id='mega-menu-item-18416'><a class="mega-menu-link" href="https://microbe-investigations.com/entomology-testing-services/#test-section/">View More</a></li> </ul> </li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18228' id='mega-menu-item-18228'><a class="mega-menu-link" href="/textile-testing/" aria-expanded="false">Textile<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18229' id='mega-menu-item-18229'><a class="mega-menu-link" href="#" aria-expanded="false">Antibacterial<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18233' id='mega-menu-item-18233'><a class="mega-menu-link" href="/iso-20743/">ISO 20743</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18231' id='mega-menu-item-18231'><a class="mega-menu-link" href="/aatcc-100/">AATCC-100</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18235' id='mega-menu-item-18235'><a class="mega-menu-link" href="/textile-testing/#test-section">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18236' id='mega-menu-item-18236'><a class="mega-menu-link" href="#" aria-expanded="false">Antiviral<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18238' id='mega-menu-item-18238'><a class="mega-menu-link" href="/jis-l-1922/">JIS L 1922</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18239' id='mega-menu-item-18239'><a class="mega-menu-link" href="/textile-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18240' id='mega-menu-item-18240'><a class="mega-menu-link" href="#" aria-expanded="false">Fungicidal & Yeasticidal<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18241' id='mega-menu-item-18241'><a class="mega-menu-link" href="/aatcc-30/">AATCC 30</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18242' id='mega-menu-item-18242'><a class="mega-menu-link" href="/textile-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18243' id='mega-menu-item-18243'><a class="mega-menu-link" href="#" aria-expanded="false">Odor Testing<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18244' id='mega-menu-item-18244'><a class="mega-menu-link" href="/iso-17299-3/">ISO 17299-3</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18245' id='mega-menu-item-18245'><a class="mega-menu-link" href="/textile-testing/">View More</a></li> </ul> </li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18246' id='mega-menu-item-18246'><a class="mega-menu-link" href="/disinfectant-testing/" aria-expanded="false">Disinfectant & Sanitizer<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18247' id='mega-menu-item-18247'><a class="mega-menu-link" href="#" aria-expanded="false">Antibacterial<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18248' id='mega-menu-item-18248'><a class="mega-menu-link" href="/en-1276/">EN 1276</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18253' id='mega-menu-item-18253'><a class="mega-menu-link" href="/disinfectant-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18254' id='mega-menu-item-18254'><a class="mega-menu-link" href="#" aria-expanded="false">Antiviral<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18255' id='mega-menu-item-18255'><a class="mega-menu-link" href="/en-14476/">EN 14476</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18260' id='mega-menu-item-18260'><a class="mega-menu-link" href="/disinfectant-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18261' id='mega-menu-item-18261'><a class="mega-menu-link" href="#" aria-expanded="false">Fungicidal & Yeasticidal<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18262' id='mega-menu-item-18262'><a class="mega-menu-link" href="/en-13624/">EN 13624</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18267' id='mega-menu-item-18267'><a class="mega-menu-link" href="/disinfectant-testing/">View More</a></li> </ul> </li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18268' id='mega-menu-item-18268'><a class="mega-menu-link" href="/plastic-testing/" aria-expanded="false">Plastic<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18269' id='mega-menu-item-18269'><a class="mega-menu-link" href="#" aria-expanded="false">Antibacterial<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18270' id='mega-menu-item-18270'><a class="mega-menu-link" href="/iso-22196/">ISO 22196</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18271' id='mega-menu-item-18271'><a class="mega-menu-link" href="/iso846/">ISO 846</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18275' id='mega-menu-item-18275'><a class="mega-menu-link" href="/plastic-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18276' id='mega-menu-item-18276'><a class="mega-menu-link" href="#" aria-expanded="false">Antiviral<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18277' id='mega-menu-item-18277'><a class="mega-menu-link" href="/iso21702/">ISO 21702</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18278' id='mega-menu-item-18278'><a class="mega-menu-link" href="/plastic-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18279' id='mega-menu-item-18279'><a class="mega-menu-link" href="#" aria-expanded="false">Fungicidal & Yeasticidal<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18280' id='mega-menu-item-18280'><a class="mega-menu-link" href="/astm-d3273-test/">ASTM D3273</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18281' id='mega-menu-item-18281'><a class="mega-menu-link" href="/iso846/">ISO 846</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18285' id='mega-menu-item-18285'><a class="mega-menu-link" href="/plastic-testing/">View More</a></li> </ul> </li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18289' id='mega-menu-item-18289'><a class="mega-menu-link" href="/cosmetic-testing/" aria-expanded="false">Cosmetics<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18290' id='mega-menu-item-18290'><a class="mega-menu-link" href="#" aria-expanded="false">Enumeration tests<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18291' id='mega-menu-item-18291'><a class="mega-menu-link" href="https://microbe-investigations.com/aerobic-plate-count-test/">Aerobic Plate Count</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18296' id='mega-menu-item-18296'><a class="mega-menu-link" href="/cosmetic-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18297' id='mega-menu-item-18297'><a class="mega-menu-link" href="#" aria-expanded="false">Detection tests<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18298' id='mega-menu-item-18298'><a class="mega-menu-link" href="/usp-60-test-for-burkholderia-cepacia-complex/">USP 60</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18303' id='mega-menu-item-18303'><a class="mega-menu-link" href="/cosmetic-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18304' id='mega-menu-item-18304'><a class="mega-menu-link" href="#" aria-expanded="false">Preservative Efficacy Tests<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18305' id='mega-menu-item-18305'><a class="mega-menu-link" href="/iso-11930/">ISO 11930</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18308' id='mega-menu-item-18308'><a class="mega-menu-link" href="/cosmetic-testing/">View More</a></li> </ul> </li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18309' id='mega-menu-item-18309'><a class="mega-menu-link" href="/coating-testing/" aria-expanded="false">Paint<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18310' id='mega-menu-item-18310'><a class="mega-menu-link" href="#" aria-expanded="false">Antibacterial<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18311' id='mega-menu-item-18311'><a class="mega-menu-link" href="/astm-d4783/">ASTM D4783</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18313' id='mega-menu-item-18313'><a class="mega-menu-link" href="/coating-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18314' id='mega-menu-item-18314'><a class="mega-menu-link" href="#" aria-expanded="false">Antiviral<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18315' id='mega-menu-item-18315'><a class="mega-menu-link" href="/iso21702/">ISO 21702</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18316' id='mega-menu-item-18316'><a class="mega-menu-link" href="/coating-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18317' id='mega-menu-item-18317'><a class="mega-menu-link" href="#" aria-expanded="false">Fungicidal & Yeasticidal<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18318' id='mega-menu-item-18318'><a class="mega-menu-link" href="/astm-d4783/">ASTM D4783</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18323' id='mega-menu-item-18323'><a class="mega-menu-link" href="/coating-testing/">View More</a></li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-item-18324' id='mega-menu-item-18324'><a class="mega-menu-link" href="#" aria-expanded="false">Antialgal<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18325' id='mega-menu-item-18325'><a class="mega-menu-link" href="/astm-d5589/">ASTM D5589</a></li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18326' id='mega-menu-item-18326'><a class="mega-menu-link" href="/coating-testing/">View More</a></li> </ul> </li> </ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-18327' id='mega-menu-item-18327'><a class="mega-menu-link" href="/more-test/">More</a></li></ul> </li><li class='mega-menu-item mega-menu-item-type-custom mega-menu-item-object-custom mega-menu-item-has-children mega-menu-megamenu mega-align-bottom-left mega-menu-grid mega-menu-item-18333' id='mega-menu-item-18333'><a class="mega-menu-link" href="#" aria-expanded="false" tabindex="0">STRAINS<span class="mega-indicator"></span></a> <ul class="mega-sub-menu"> <li class='mega-menu-row' id='mega-menu-18333-0'> <ul class="mega-sub-menu"> <li class='mega-menu-column mega-menu-columns-12-of-12' id='mega-menu-18333-0-0'> <ul class="mega-sub-menu"> <li class='mega-menu-item mega-menu-item-type-widget widget_elementor-library mega-menu-item-elementor-library-4' id='mega-menu-item-elementor-library-4'> <div data-elementor-type="section" data-elementor-id="18336" class="elementor elementor-18336" data-elementor-post-type="elementor_library"> <div class="elementor-element elementor-element-6679b94b e-con-full e-flex e-con e-parent" data-id="6679b94b" data-element_type="container"> <div class="elementor-element 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href="https://microbe-investigations.com/disinfectant-validation/">Disinfectant Validation: Ensuring Effective Infection Control</a></h2> </div> </div> <div class="elementor-element elementor-element-2a93bc71 elementor-position-left elementor-vertical-align-middle elementor-position-left elementor-vertical-align-top elementor-widget elementor-widget-image-box" data-id="2a93bc71" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><img src="https://secure.gravatar.com/avatar/71cd24bb4f43b9984f75607516782169?s=96&d=mm&r=g" title="" alt="" loading="lazy" /></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title">Content Team</h3><p class="elementor-image-box-description">by Monday, 28th Oct 2024</p></div></div> </div> </div> </div> <div class="elementor-element elementor-element-7ed2d6d8 e-con-full e-flex e-con e-child" 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data-social="linkedin"> <div class="linkedin"> <i aria-hidden="true" class="fab fa-linkedin-in"></i> </div> </li> </ul> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-1f062a44 e-con-full e-flex e-con e-child" data-id="1f062a44" data-element_type="container"> <div class="elementor-element elementor-element-2145f365 elementor-widget__width-inherit elementor-widget elementor-widget-image" data-id="2145f365" data-element_type="widget" data-widget_type="image.default"> <div class="elementor-widget-container"> <img width="2560" height="1441" src="https://microbe-investigations.com/wp-content/uploads/2024/10/Disinfectant-validation-scaled.jpg" class="attachment-full size-full wp-image-17558" alt="Disinfectant Validation" srcset="https://microbe-investigations.com/wp-content/uploads/2024/10/Disinfectant-validation-scaled.jpg 2560w, https://microbe-investigations.com/wp-content/uploads/2024/10/Disinfectant-validation-300x169.jpg 300w, https://microbe-investigations.com/wp-content/uploads/2024/10/Disinfectant-validation-1024x576.jpg 1024w, https://microbe-investigations.com/wp-content/uploads/2024/10/Disinfectant-validation-768x432.jpg 768w, https://microbe-investigations.com/wp-content/uploads/2024/10/Disinfectant-validation-1536x864.jpg 1536w, https://microbe-investigations.com/wp-content/uploads/2024/10/Disinfectant-validation-2048x1153.jpg 2048w" sizes="(max-width: 2560px) 100vw, 2560px" /> </div> </div> </div> <div class="elementor-element elementor-element-e7ce709 e-con-full e-flex e-con e-child" data-id="e7ce709" data-element_type="container"> <div class="elementor-element elementor-element-67a72aa7 e-con-full content_blog e-flex e-con e-child" data-id="67a72aa7" data-element_type="container"> <div class="elementor-element elementor-element-72e8d32b elementor-widget elementor-widget-theme-post-content" data-id="72e8d32b" data-element_type="widget" data-widget_type="theme-post-content.default"> <div class="elementor-widget-container"> <p>In industries like healthcare, pharmaceuticals and biotechnology, maintaining high levels of cleanliness and hygiene is crucial for preventing infections and contamination. Disinfectant validation is the process that ensures disinfectants used in these environments are effective against a wide spectrum of microorganisms, including bacteria, viruses, fungi and spores. Disinfectant validation ensures that cleaning and disinfection protocols are both reliable and effective in reducing contamination risks. </p> <p>This article explores the key aspects of disinfectant validation, including the relevant terminology, regulatory framework, key components of validation reports and challenges associated with validation.</p> <h2 class="wp-block-heading" id="h-definitions-and-terminology-for-antimicrobial-products">Definitions and terminology for antimicrobial products</h2> <p></p> <p>In order to briefly present the details of disinfectant validation it is necessary to understand the terminology concerning antimicrobial products.</p> <ul class="wp-block-list"> <li><strong>Disinfectants</strong>: Chemical agents which destroy or inactivate microorganisms on inanimate objects and surfaces. Disinfectants act against bacteria, viruses and fungi but may not necessarily destroy bacterial spores.</li> <li><strong>Sporicides</strong>: One of the subset of disinfectants formulated specifically to kill bacterial spores since they tend to be more resistant to the action of chemical agents than other types of microorganisms.</li> <li><strong>Antiseptics</strong>: Similar to disinfectants, except these products work on living tissue such as human skin to reduce the number of microorganisms.</li> <li><strong>Sanitizers</strong>: Agents used to reduce the number of microorganisms to a safe number. Typically applied in food-preparation environments and community health environments.</li> </ul> <p>All these antimicrobial agents play an important role in preventing and controlling infections. Their approval ensures they are applied appropriately within their intended environment.</p> <h2 class="wp-block-heading" id="h-what-are-disinfectants">What are disinfectants?</h2> <p></p> <p>Disinfectants are chemical agents specifically designed to inactivate or destroy microorganisms on surfaces and thus they provide a crucial service in maintaining a sterile environment for healthcare, laboratories and manufacturing. Disinfectants differ depending on their spectrum of action. Broad-spectrum disinfectants act against a wide spectrum of microorganisms, to relatively narrow-spectrum and specialized disinfectant formulation that targets either bacteria, viruses, or fungi.</p> <p>There are several types of disinfectants, including:</p> <ul class="wp-block-list"> <li><strong>Alcohol-based disinfectants</strong>: These work fast but are volatile and are often used for medical instruments.</li> <li><strong>Phenolic disinfectants</strong>: Effective against most pathogens which are widely used in health-care facilities.</li> <li><strong>Quaternary ammonium compounds</strong>: Effective against many pathogens, commonly used in healthcare settings.</li> <li><strong>Chlorine compounds</strong>: Highly effective but corrosive to surfaces and degrade organic materials.</li> </ul> <h2 class="wp-block-heading" id="h-what-are-sporicides">What are sporicides?</h2> <p></p> <p>Sporicides are chemical disinfectants specifically designed to inactivate spores, which are the most resistant forms of microbes. They are particularly applied in sterility demanding situations-for example, in pharmaceuticals, cleanrooms and hospital use. Bacterial spores such as <em>Clostridium</em> <em>difficile</em> and <em>Bacillus anthracis</em> survive physical and chemical stresses and disinfectants lethal to other types of microbes. Thus, sporicides form one of the pillars upon which a disinfection strategy is built in high-risk situations.</p> <h2 class="wp-block-heading" id="h-regulatory-framework-for-disinfectant-validation-protocol">Regulatory framework for disinfectant validation protocol</h2> <p></p> <p>The regulatory framework governing disinfectant validation is comprehensive, involving guidelines and standards from various national and international bodies. In the pharmaceutical industry, disinfectant validation is typically required by regulatory bodies such as the FDA (Food and Drug Administration) in the United States and EMA (European Medicines Agency) in Europe. These agencies require thorough validation to ensure that disinfectants are effective and appropriate for use in cleanrooms, sterile production environments, and healthcare settings.</p> <p>ISO standards also play a crucial role in the regulatory framework. For example, <strong>ISO 14698</strong> provides guidance on biocontamination control. The regulatory framework ensures that disinfectants used in critical environments are validated based on their ability to eliminate specific microbial contaminants.</p> <h2 class="wp-block-heading">Efficacy testing of disinfectants</h2> <p></p> <p>Efficacy testing of disinfectants is the process of determining the efficiency of a disinfectant to remove or reduce microbial populations on surfaces. It is conducted under laboratory conditions and, in some cases, under real-time environments to simulate the practical applications of the disinfectant. The log reduction method primarily used for quantifying the efficacy is one, wherein higher log reduction means greater efficiency in killing the targeted microorganisms.</p> <p>This testing usually involves:</p> <ul class="wp-block-list"> <li><strong>Surface testing</strong>: Ability of a disinfectant to clean various surfaces, for example, stainless steel, glass, or plastics.</li> <li><strong>Contact time</strong>: Determining the amount of time the disinfectant needs to remain on a surface to be effective.</li> <li><strong>Environmental testing</strong>: Testing the disinfectant under real-world conditions, such as in cleanrooms or healthcare environments.</li> </ul> <h2 class="wp-block-heading">Key components of a disinfectant validation report</h2> <p></p> <p>A validation report of a disinfectant is crucial as it captures all aspects of the process, thus making the process transparent and traceable. The report contains details about: </p> <ol class="wp-block-list"> <li><strong>Objective</strong>: Clear statement of the goal. Ensuring that the disinfectant remains effective against the microorganisms of interest in the environment of use.</li> <li><strong>Methodology</strong>: Includes detailed description of the testing methods used, involving the selection of microorganisms, test surfaces and concentrations of the disinfectant and times of exposure.</li> <li><strong>Test microorganisms</strong>: Selection of representative microorganisms, including bacteria, fungi, viruses and spores, which are relevant to the environment being disinfected.</li> <li><strong>Results</strong>: Complete data set documenting efficacy of the disinfectant. This entails log reduction values for microbial counts before and after disinfection.</li> <li><strong>Conclusions</strong>: Summary of the results, confirming whether the disinfectant met the efficacy requirements.</li> <li><strong>Recommendations</strong>: Recommendations for any change in the cleaning protocol based on validation results.</li> </ol> <h2 class="wp-block-heading">Registration of antimicrobial products for validation of disinfectants</h2> <p></p> <p>The registration is important for the registration of antimicrobial products because the disinfectants need to be approved in terms of safety and effectiveness dictated by the standards. Registration in the United States is maintained with the Environmental Protection Agency, while in Europe, it falls under the Biocidal Products Regulation (BPR). Agencies require significant data to prove that the product is safe for its intended use and effective against relevant microorganisms.</p> <p>Registration prerequisites include a dataset of efficacy obtained from validation studies. Such studies are considered to be the basis on which claims about the efficacy of the disinfectant against specific microbial contaminants are made.</p> <h2 class="wp-block-heading">Challenges in disinfectant validation</h2> <p></p> <p>Disinfectant validation comes with several challenges, including:</p> <ul class="wp-block-list"> <li><strong>Environmental variability</strong>: The practical application of disinfectants occurs at specific temperatures, level of moisture or even the types of surfaces affecting their effectiveness.</li> <li><strong>Complex microbial communities</strong>: Some environments may have biofilms or a diversity of microorganisms that are more resistant to disinfectants, complicating validation in some environments.</li> <li><strong>Surface compatibility</strong>: The same disinfectant can respond differently to various surfaces and may cause corrosion or degradation. Consequently, compatibility with surfaces is important.</li> </ul> <h2 class="wp-block-heading">Importance of disinfectant validation</h2> <p></p> <p>Disinfectant validation is important because it ensures the cleaning protocols are effective and safe in areas where contamination poses a great danger, such as healthcare facilities, pharmaceutical manufacturing, or food processing plants. Proper validation protects the products from cross-contamination, healthcare-acquired infections and product recalls, among other issues. Eventually meeting regulatory requirements.</p> <h2 class="wp-block-heading">Conclusion</h2> <p></p> <p>The validation of disinfectants is an important document for ensuring the effectiveness and safety of the disinfectant in its application within high-precaution environments. The process ensures disinfectants are frequently effective in real-life situations. Disinfectant companies ensuring compliance according to high regulatory standards should invest in professional testing services.</p> <p>For disinfectant manufacturers looking to validate their products, Microbe Investigations Switzerland (MIS) offers expert validation and testing services that ensure compliance, efficacy and safety. <strong><a href="https://microbe-investigations.com/contact-us/">Contact MIS today</a></strong> to learn more about how our validation services can elevate your product’s quality and regulatory compliance.</p> <h2 class="wp-block-heading" id="h-faqs">FAQs</h2> <p></p> <h4 class="wp-block-heading" id="h-1-why-is-disinfectant-validation-important"><strong>1. Why is disinfectant validation important?</strong></h4> <p><strong><br></strong>Disinfectant validation provides evidence that disinfectants eliminate pathogens under controlled conditions while eliminating microbes and maintaining regulatory compliance.</p> <h4 class="wp-block-heading" id="h-2-how-is-disinfectant-validation-performed"><strong>2. How is disinfectant validation performed?</strong></h4> <p><strong><br></strong>Disinfectant validation is carried out by testing the product’s efficacy on a range of microbial strains on surfaces pertinent to where it is going to be applied.</p> <h4 class="wp-block-heading" id="h-3-what-is-the-difference-between-disinfectant-validation-and-disinfectant-efficacy-testing"><strong>3. What is the difference between disinfectant validation and disinfectant efficacy testing?</strong></h4> <p><strong><br></strong>Disinfectant validation tests its efficacy in a specific environment, whereas effectiveness tests its general antimicrobial capacity.</p> <h4 class="wp-block-heading" id="h-4-what-is-the-cost-of-disinfectant-validation"><strong>4. What is the cost of disinfectant validation?</strong></h4> <p><strong><br></strong>The cost of disinfectant validation is set by the testing complexity and number of strains and type of surfaces.</p> <h4 class="wp-block-heading" id="h-5-how-often-should-disinfectant-validation-be-performed"><strong>5. How often should disinfectant validation be performed?</strong></h4> <p><strong><br></strong>Validation of disinfectants should be done on a periodic basis. 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<span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-angle-right"></i> </span> <span class="elementor-button-text">Explore now</span> </span> </a> </div> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-4c1cd76e e-con-full e-flex e-con e-parent" data-id="4c1cd76e" data-element_type="container" data-settings="{"background_background":"classic"}"> <div class="elementor-element elementor-element-7be9109e e-con-full e-flex e-con e-child" data-id="7be9109e" data-element_type="container"> <div class="elementor-element elementor-element-3144c41 e-con-full e-flex e-con e-child" data-id="3144c41" data-element_type="container"> <div class="elementor-element elementor-element-6df41925 e-con-full e-flex e-con e-child" data-id="6df41925" data-element_type="container"> <div class="elementor-element elementor-element-34eab67e elementor-widget-mobile__width-inherit elementor-widget elementor-widget-image" data-id="34eab67e" data-element_type="widget" data-widget_type="image.default"> <div class="elementor-widget-container"> <img width="160" height="160" src="https://microbe-investigations.com/wp-content/uploads/2024/11/image-27.png" class="attachment-large size-large wp-image-18520" alt="" srcset="https://microbe-investigations.com/wp-content/uploads/2024/11/image-27.png 160w, https://microbe-investigations.com/wp-content/uploads/2024/11/image-27-150x150.png 150w" sizes="(max-width: 160px) 100vw, 160px" /> </div> </div> </div> <div class="elementor-element elementor-element-2d8e22a1 e-con-full e-flex e-con e-child" data-id="2d8e22a1" data-element_type="container"> <div class="elementor-element elementor-element-28708b7d elementor-widget elementor-widget-text-editor" data-id="28708b7d" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> We also partner with over 16 labs (both GLP and non-GLP) for extended support. </div> </div> </div> </div> </div> </div> </div> </div> </div> <footer id="colophon" role="contentinfo"> <div class='footer-width-fixer'> <div data-elementor-type="wp-post" data-elementor-id="18202" class="elementor elementor-18202" data-elementor-post-type="elementor-hf"> <div class="elementor-element elementor-element-4d665360 e-con-full e-flex e-con e-parent" data-id="4d665360" data-element_type="container" data-settings="{"background_background":"classic"}"> <div class="elementor-element elementor-element-268ae611 e-con-full e-flex e-con e-child" data-id="268ae611" data-element_type="container"> <div class="elementor-element elementor-element-3dcae561 e-con-full e-flex e-con e-child" data-id="3dcae561" data-element_type="container"> <div class="elementor-element elementor-element-110f5eaf e-con-full e-flex e-con e-child" data-id="110f5eaf" data-element_type="container"> <div class="elementor-element elementor-element-1d0905e2 elementor-widget elementor-widget-heading" data-id="1d0905e2" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">STRAINS</p> </div> </div> <div class="elementor-element elementor-element-513a74e2 footer-btns elementor-widget elementor-widget-button" data-id="513a74e2" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="/insects/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-arrow-right"></i> </span> <span class="elementor-button-text">Insects</span> </span> </a> </div> </div> </div> <div class="elementor-element elementor-element-64351df2 footer-btns elementor-widget elementor-widget-button" data-id="64351df2" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="/bacteria/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-arrow-right"></i> </span> <span class="elementor-button-text">Bacteria</span> </span> </a> </div> </div> </div> <div class="elementor-element elementor-element-31b91bf8 footer-btns elementor-widget elementor-widget-button" data-id="31b91bf8" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="/virus-strain/%20"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-arrow-right"></i> </span> <span class="elementor-button-text">Virus</span> </span> </a> </div> </div> </div> <div class="elementor-element elementor-element-cb003e8 footer-btns elementor-widget elementor-widget-button" data-id="cb003e8" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="/fungi-strains/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-arrow-right"></i> </span> <span class="elementor-button-text">Fungi</span> </span> </a> </div> </div> </div> </div> <div class="elementor-element elementor-element-3983e50e elementor-widget-divider--view-line elementor-widget elementor-widget-divider" data-id="3983e50e" data-element_type="widget" data-widget_type="divider.default"> <div class="elementor-widget-container"> <div class="elementor-divider"> <span class="elementor-divider-separator"> </span> </div> </div> </div> <div class="elementor-element elementor-element-c182ad6 e-con-full e-flex e-con e-child" data-id="c182ad6" data-element_type="container"> <div class="elementor-element elementor-element-216eab67 elementor-widget elementor-widget-heading" data-id="216eab67" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">TESTING</p> </div> </div> <div class="elementor-element elementor-element-4f818d16 footer-btns elementor-widget elementor-widget-button" data-id="4f818d16" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="/entomology-testing-services/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-arrow-right"></i> </span> <span class="elementor-button-text">Entomology Testing</span> </span> </a> </div> </div> </div> <div class="elementor-element elementor-element-3c0ad7a7 footer-btns elementor-widget elementor-widget-button" data-id="3c0ad7a7" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="/antibacterial/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-arrow-right"></i> </span> <span class="elementor-button-text">Antibacterial testing</span> </span> </a> </div> </div> </div> <div class="elementor-element elementor-element-2421d46e footer-btns elementor-widget elementor-widget-button" data-id="2421d46e" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="/antiviral/"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-arrow-right"></i> </span> <span class="elementor-button-text">Antiviral testing</span> </span> </a> </div> </div> </div> <div class="elementor-element elementor-element-602b1c55 footer-btns elementor-widget elementor-widget-button" data-id="602b1c55" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-button-link elementor-size-sm" href="#"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-icon"> <i aria-hidden="true" class="fas fa-arrow-right"></i> </span> <span class="elementor-button-text">odor testing</span> </span> </a> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-45b3cfe0 e-con-full e-flex e-con e-child" data-id="45b3cfe0" data-element_type="container"> <div class="elementor-element elementor-element-526b9a17 elementor-widget elementor-widget-heading" data-id="526b9a17" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">Industry tests</p> </div> </div> <div class="elementor-element elementor-element-75337ffb e-con-full e-flex e-con e-child" data-id="75337ffb" data-element_type="container"> <div class="elementor-element elementor-element-40a80243 e-con-full e-flex e-con e-child" data-id="40a80243" data-element_type="container"> <div class="elementor-element elementor-element-733e5d56 elementor-widget elementor-widget-text-editor" data-id="733e5d56" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> entomology </div> </div> <div class="elementor-element elementor-element-2e6ed731 elementor-widget-divider--view-line elementor-widget elementor-widget-divider" data-id="2e6ed731" data-element_type="widget" data-widget_type="divider.default"> <div class="elementor-widget-container"> <div class="elementor-divider"> <span class="elementor-divider-separator"> </span> </div> </div> </div> <div class="elementor-element elementor-element-6e55d5e8 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list" data-id="6e55d5e8" data-element_type="widget" data-widget_type="icon-list.default"> <div class="elementor-widget-container"> <ul class="elementor-icon-list-items"> <li class="elementor-icon-list-item"> <a href="/arm-in-cage-test/"> <span class="elementor-icon-list-text">Arm in cage Test</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/room-test/"> <span class="elementor-icon-list-text">Room test</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/olfactometer-test/"> <span class="elementor-icon-list-text">Olfactometer test</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/tick-repellent-testing/"> <span class="elementor-icon-list-text">Tick repellent testing</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/bed-bug-repellency-test/"> <span class="elementor-icon-list-text">Bed bug repellency test</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/peet-grady-chamber-test/"> <span class="elementor-icon-list-text">Peet-Grady Chamber Test</span> </a> </li> </ul> </div> </div> </div> <div class="elementor-element elementor-element-610a1a81 e-con-full e-flex e-con e-child" data-id="610a1a81" data-element_type="container"> <div class="elementor-element elementor-element-613177fc e-con-full e-flex e-con e-child" data-id="613177fc" data-element_type="container"> <div class="elementor-element elementor-element-625dd390 elementor-widget elementor-widget-text-editor" data-id="625dd390" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> Textiles </div> </div> <div class="elementor-element elementor-element-3964b572 elementor-widget-divider--view-line elementor-widget elementor-widget-divider" data-id="3964b572" data-element_type="widget" data-widget_type="divider.default"> <div class="elementor-widget-container"> <div class="elementor-divider"> <span class="elementor-divider-separator"> </span> </div> </div> </div> <div class="elementor-element elementor-element-7279c68f elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list" data-id="7279c68f" data-element_type="widget" data-widget_type="icon-list.default"> <div class="elementor-widget-container"> <ul class="elementor-icon-list-items"> <li class="elementor-icon-list-item"> <a href="/aatcc-100/"> <span class="elementor-icon-list-text">AATCC 100</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/jisl1902/"> <span class="elementor-icon-list-text">JIS L 1902</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/iso-20743/"> <span class="elementor-icon-list-text">ISO 20743</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/astm-e2149/"> <span class="elementor-icon-list-text">ASTM E2149</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/aatcc-147/"> <span class="elementor-icon-list-text">AATCC 147</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/iso18184/"> <span class="elementor-icon-list-text">ISO 18184</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/jis-l-1922/"> <span class="elementor-icon-list-text">JIS L 1922</span> </a> </li> </ul> </div> </div> </div> </div> <div class="elementor-element elementor-element-31f2c0aa e-con-full e-flex e-con e-child" data-id="31f2c0aa" data-element_type="container"> <div class="elementor-element elementor-element-2b1a9619 e-con-full e-flex e-con e-child" data-id="2b1a9619" data-element_type="container"> <div class="elementor-element elementor-element-2098b14a elementor-widget elementor-widget-text-editor" data-id="2098b14a" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> Disinfectants </div> </div> <div class="elementor-element elementor-element-f72b6c7 elementor-widget-divider--view-line elementor-widget elementor-widget-divider" data-id="f72b6c7" data-element_type="widget" data-widget_type="divider.default"> <div class="elementor-widget-container"> <div class="elementor-divider"> <span class="elementor-divider-separator"> </span> </div> </div> </div> <div class="elementor-element elementor-element-1c6de593 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list" data-id="1c6de593" data-element_type="widget" data-widget_type="icon-list.default"> <div class="elementor-widget-container"> <ul class="elementor-icon-list-items"> <li class="elementor-icon-list-item"> <a href="/en-1276/"> <span class="elementor-icon-list-text">EN 1276</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/en-16615/"> <span class="elementor-icon-list-text">EN 16615</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/astm-e1053/"> <span class="elementor-icon-list-text">ASTM E1053</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/en-16777/"> <span class="elementor-icon-list-text">EN 16777</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/en-13697/"> <span class="elementor-icon-list-text">EN 13697</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/en-13727/"> <span class="elementor-icon-list-text">EN 13727</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/pas-2424/"> <span class="elementor-icon-list-text">PAS 2424</span> </a> </li> </ul> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-efd5b43 e-con-full e-flex e-con e-child" data-id="efd5b43" data-element_type="container"> <div class="elementor-element elementor-element-8e3325b e-con-full e-flex e-con e-child" data-id="8e3325b" data-element_type="container"> <div class="elementor-element elementor-element-6d9191c8 elementor-widget elementor-widget-text-editor" data-id="6d9191c8" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> Cosmetics </div> </div> <div class="elementor-element elementor-element-493cf9bc elementor-widget-divider--view-line elementor-widget elementor-widget-divider" data-id="493cf9bc" data-element_type="widget" data-widget_type="divider.default"> <div class="elementor-widget-container"> <div class="elementor-divider"> <span class="elementor-divider-separator"> </span> </div> </div> </div> <div class="elementor-element elementor-element-6f4e1a63 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list" data-id="6f4e1a63" data-element_type="widget" data-widget_type="icon-list.default"> <div class="elementor-widget-container"> <ul class="elementor-icon-list-items"> <li class="elementor-icon-list-item"> <a href="/usp-62-test/"> <span class="elementor-icon-list-text">USP 62</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/usp-61-microbial-enumeration-test/"> <span class="elementor-icon-list-text">USP 61</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/pcpc-test-methods/"> <span class="elementor-icon-list-text">PCPC Test Methods</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/iso-21322/"> <span class="elementor-icon-list-text">ISO 21322</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/iso-18416/"> <span class="elementor-icon-list-text">ISO 18416</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/iso-21149/"> <span class="elementor-icon-list-text">ISO 21149</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/usp-51-antimicrobial-effectiveness-test/"> <span class="elementor-icon-list-text">USP 51</span> </a> </li> </ul> </div> </div> </div> <div class="elementor-element elementor-element-3c02985b e-con-full e-flex e-con e-child" data-id="3c02985b" data-element_type="container"> <div class="elementor-element elementor-element-79c0d60a e-con-full e-flex e-con e-child" data-id="79c0d60a" data-element_type="container"> <div class="elementor-element elementor-element-4a56787e elementor-widget elementor-widget-text-editor" data-id="4a56787e" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> Plastics & COATINGS </div> </div> <div class="elementor-element elementor-element-61cf463d elementor-widget-divider--view-line elementor-widget elementor-widget-divider" data-id="61cf463d" data-element_type="widget" data-widget_type="divider.default"> <div class="elementor-widget-container"> <div class="elementor-divider"> <span class="elementor-divider-separator"> </span> </div> </div> </div> <div class="elementor-element elementor-element-14f697b4 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list" data-id="14f697b4" data-element_type="widget" data-widget_type="icon-list.default"> <div class="elementor-widget-container"> <ul class="elementor-icon-list-items"> <li class="elementor-icon-list-item"> <a href="/iso846/"> <span class="elementor-icon-list-text">ISO 846</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/astm-e2180/"> <span class="elementor-icon-list-text">ASTM E2180</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/astm-g22/"> <span class="elementor-icon-list-text">ASTM G22</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/astm-d3273-test/"> <span class="elementor-icon-list-text">ASTM D3273</span> </a> </li> <li class="elementor-icon-list-item"> <a href="/astm-c1338/"> <span 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