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class="ecl-page-header__description-container"><p class="ecl-page-header__description">The JRC is one of the major developers and producers of reference materials, which are produced in support of EU policy. </p></div></div></div> </div> <main class="ecl-u-pb-xl" id="main-content" data-inpage-navigation-source-area="h2.ecl-u-type-heading-2, div.ecl-featured-item__heading"> <div class="ecl-container"> <div class="ecl-row"> <div class="ecl-col-s-12 ewcms-top-sidebar"> <div> <div data-drupal-messages-fallback class="hidden"></div> </div> </div> </div> <div class="ecl-row"> <div class="ecl-col-s-12"> <div id="block-ewcms-theme-main-page-content" data-inpage-navigation-source-area="h2, div.ecl-featured-item__heading" class="ecl-u-mb-l"> <article dir="ltr"> <div> <dl class="ecl-description-list ecl-description-list--horizontal ecl-u-mb-s ecl-u-mt-s" ><dt class="ecl-description-list__term">Contributes to EC priorities:</dt><dd class="ecl-description-list__definition ecl-description-list__definition--taxonomy"><ul class="ecl-description-list__definition-list"><li class="ecl-description-list__definition-item"><a href="https://joint-research-centre.ec.europa.eu/science-promoting-our-european-way-life_en" class="ecl-link" >Promoting our European way of life</a></li></ul></dd></dl> <div class="ecl-u-mb-2xl"> <a id="paragraph_5020"></a> <div class="ecl"><p>JRC's selection of RMs are tailored to meet the current and future needs of EU policy. Reliable and comparable measurement results are key to reduce health-care costs, improve clinical management and lower the risk of medical error. Efficient, resilient and safer food production systems rely on verification through monitoring and measurements. The reduction of pollutants in the environment to levels no longer considered harmful to humans and nature requires consistent monitoring are based on reliable measurement results. The competitiveness of the EU economy and the smooth functioning of international trade also depend on reliable measurements. State-of-the-art RMs can also play a crucial role in emerging EU focus areas such as biotechnology and preparedness and response to health crises like pandemics or widespread food products contaminations.</p><p>At the heart of reliable measurements are RMs. They provide a benchmark for analytical laboratories around the world to deliver accurate results. Testing laboratories use CRMs to calibrate their measuring instruments. Additionally, RMs are also used as quality control assurance tools, proving that obtained measurement results are correct, helping to eliminate the need to duplicate or dispute testing data.</p><p>The JRC is one of the major developers and producers of reference materials in the world. It currently provides over 760 reference materials under the BCR, IRMM, EURM and ERM brands, and distributes around 20,000 units per year to testing laboratories worldwide. The JRC has RM production facilities unique in the world, including specialised laboratories and a pilot plant for material processing. </p><p>JRC鈥檚 reference materials can be ordered directly from the JRC, Geel or from one of its authorised distributors.</p><p>Check the <a href="https://crm.jrc.ec.europa.eu/">Certified Reference Materials Catalogue</a> for the full catalogue of reference materials, ordering, user support, application noticed and frequently asked questions.</p></div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5167"></a> <div class="ecl-content-item-block"><div class="ecl-row"><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-3 "><article class="ecl-card" ><picture class="ecl-picture ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2013-05/jrc-irmm-rms-for-clinical-chemistry_0.jpg?itok=h5jNEP5_" alt="jrc-irmm-rms-for-clinical-chemistry_0.jpg" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="/scientific-activities-z/certified-reference-materials/reference-materials-clinical-analysis_en?prefLang=sl" class="ecl-link ecl-link--standalone" >Reference materials for clinical analysis</a></div><div class="ecl-content-block__description"><div class="ecl"><p>Good health care requires reliable measurements of health status and disease markers. The results of such In-Vitro diagnostics measurements need to be comparable between different laboratories, and over time.</p></div></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-3 "><article class="ecl-card" ><picture class="ecl-picture ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2013-07/reference_material_for_environmental_analysis.jpg?itok=rEak-gcl" alt="A number of small glass bottles containing reference materials." ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="/scientific-activities-z/certified-reference-materials/reference-materials-environmental-analysis_en?prefLang=sl" class="ecl-link ecl-link--standalone" >Reference materials for environmental analysis</a></div><div class="ecl-content-block__description"><div class="ecl"><p>The JRC provides state-of-the-art certified reference materials as quality assurance and quality control tools for the implementation of EU environmental policies.</p></div></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-3 "><article class="ecl-card" ><picture class="ecl-picture ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2013-07/reference-materials-for-food-analysis.jpg?itok=Xumyotoq" alt="Reference materials for food analysis" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="https://joint-research-centre.ec.europa.eu/scientific-activities-z/reference-materials-food-analysis_en" class="ecl-link ecl-link--standalone" >Reference materials for food analysis</a></div><div class="ecl-content-block__description"><div class="ecl"><p>The certified reference materials distributed by the JRC give measurement laboratories a means to validate analytical methods, to assess the quality of the measurement results and to demonstrate their traceability to stated references such as the SI.</p></div></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-3 "><article class="ecl-card" ><picture class="ecl-picture ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2015-01/gmo_crm_bottles.jpg?itok=z_pTIJHO" alt="gmo_crm_bottles.jpg" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="/scientific-activities-z/certified-reference-materials/reference-materials-gmo-analysis_en?prefLang=sl" class="ecl-link ecl-link--standalone" >Reference materials for GMO analysis</a></div><div class="ecl-content-block__description"><div class="ecl"><p>For the implementation of the European legislation that regulates the authorisation and the labelling of genetically modified organisms (GMOs), the JRC develops, produces and distributes certified reference materials.</p></div></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-3 last-item-column"><article class="ecl-card" ><picture class="ecl-picture ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2024-07/2018_Two%20CRMs%20for%20trace%20elements%20in%20titanium_ERM-EB090_5.jpg?h=2992ba0a&itok=0ja7c7-X" alt="Two CRMs for trace elements in titanium - ERM-EB090" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="/scientific-activities-z/certified-reference-materials/reference-materials-materials-science_en?prefLang=sl" class="ecl-link ecl-link--standalone" >Reference materials for materials science</a></div><div class="ecl-content-block__description"><div class="ecl"><p>Reference materials for materials science underpin many industrial processes and give companies as well as regulators the confidence in these measurements that strengthen assessments of legal as well as company and customer-specific specifications.</p></div></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-3 last-item-column"><article class="ecl-card" ><picture class="ecl-picture ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2013-07/Metrological%2520tools%2520for%2520safeguards%2520activities.jpg?itok=77qC_GEW" alt="Metrological tools for safeguards activities" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="/scientific-activities-z/reference-materials-nuclear-safeguards-safety-and-security_en?prefLang=sl" class="ecl-link ecl-link--standalone" >Reference materials for nuclear safeguards, safety and security</a></div><div class="ecl-content-block__description"><div class="ecl"><p>Verification and detection in safeguarding nuclear material, conformity of information on materials and processes in nuclear forensics, as well as response in nuclear security are based on reliable measurement results with appropriate quality control.</p></div></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-3 last-item-column"><article class="ecl-card" ><picture class="ecl-picture ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2020-12/nano_rm_13022012-capture0002_v2.jpg?itok=LFiu0aL9" alt="nano_rm_13022012-capture0002_v2.jpg" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="/scientific-activities-z/nanotechnology_en?prefLang=sl" class="ecl-link ecl-link--standalone" >Nanotechnology</a></div><div class="ecl-content-block__description"><div class="ecl"><p>JRC research on nanotechnology contributes to the reduction of uncertainties about the potential impact of nanomaterials on health and the environment and supports the development of a sound regulatory framework by providing informed science-based.</p></div></div></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-3 last-item-column last-item"><article class="ecl-card" ><picture class="ecl-picture ecl-card__picture" data-ecl-picture-link ><img class="ecl-card__image" src="/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2013-07/Reference%2520materials%2520for%2520nuclear%2520safeguards%252C%2520safety%2520and%2520security.jpg?itok=MveaLmsZ" alt="Reference materials for nuclear safeguards, safety and security" ></picture><div class="ecl-card__body"><div class="ecl-content-block ecl-card__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="https://joint-research-centre.ec.europa.eu/scientific-activities-z/nuclear-reference-data-materials-and-measurements_en" class="ecl-link ecl-link--standalone" >Nuclear reference data, materials and measurements</a></div><div class="ecl-content-block__description"><div class="ecl"><p>Reliable measurements of 伪, 尾 and 纬 radiation are of great importance for environmental monitoring, medical treatment and nuclear safeguards.</p></div></div></div></div></article></div></div></div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5243"></a> <h2 class="ecl-u-type-heading-2">Reference materials for fuel</h2> <div class="ecl"><p>Fuel quality is an important energy issue for industry as well as for citizens. When using fuels in car engines or domestic heating, systems consumers need to be sure that the fuel does not cause any malfunction or damage to their equipment. Similarly, consumers are increasingly aware also of the environmental impact of their fuel consumption. The JRC provides certified reference materials for fuel analysis for a wide range of parameters relevant for the quality and environmental impact of fuels, be it conventional fossil fuels or biofuels.</p></div> </div> <div class="ecl-u-mb-2xl"> <a id="paragraph_5030"></a> <h2 class="ecl-u-type-heading-2">Reference materials development</h2> <div class="ecl"><p>EU policy needs drive the development of reference materials at the JRC.</p><p>Therefore, JRC has to provide certified reference materials which are crucial as anchor points for the calibration of measurements in complex natural and man-made systems and for the benchmarking of and within control and reference laboratories. New reference material developments will be focused on scientifically cutting-edge materials with new measurand/matrix combinations and material properties as close as feasible to the real-world samples to be controlled for EU legislation.</p><p>The main areas cover:</p><ul><li>biotechnologies and molecular biosciences</li><li>health</li><li>environment and energy</li><li>advanced engineered materials including nanotechnology</li><li>safe and high-quality food</li><li>nuclear safeguards</li></ul><p>The reference function of the JRC implies also the need to ensure the provision of crucial reference materials on a long-term scale.</p><p>JRC has established a modern quality management system. Since 2004 the Unit is accredited according to ISO 17034 (which replaced ISO Guide 34 in 2016) and ISO/IEC 17025.</p><p>Most of the reference material projects are performed in collaboration with various external institutions and JRC invites competent parties to express their related interests.</p> <div class="ecl-media-container ecl-media-container--custom-ratio ecl-u-mb-s" data-ecl-media-container="true" data-ecl-auto-init="MediaContainer"><figure class="ecl-media-container__figure"><div class="ecl-media-container__media"><picture><source srcset="/sites/default/files/styles/oe_theme_medium_no_crop/public/2013-07/reference-materials_0.jpg?itok=5WJ0lRW5 1x, /sites/default/files/styles/oe_theme_medium_2x_no_crop/public/2013-07/reference-materials_0.jpg?itok=mk9gtYqT 2x" media="all and (min-width: 768px)" type="image/jpeg" width="733" height="155"></source><source srcset="/sites/default/files/styles/oe_theme_small_no_crop/public/2013-07/reference-materials_0.jpg?itok=cCpB8DtX 1x, /sites/default/files/styles/oe_theme_small_2x_no_crop/public/2013-07/reference-materials_0.jpg?itok=09WgiVkb 2x" type="image/jpeg" width="733" height="155"></source><img loading="eager" class="ecl-u-width-100 ecl-u-height-auto ecl-media-container__media--ratio-custom" src="/sites/default/files/styles/oe_theme_medium_no_crop/public/2013-07/reference-materials_0.jpg?itok=5WJ0lRW5" width="733" height="155" alt="Reference materials production hall (JRC-IRMM)" title="reference-materials_0.jpg"></picture></div></figure></div> <p>Reference materials production hall (JRC, Geel, Belgium)</p></div> </div> </div> </article> </div> <div data-inpage-navigation-source-area="h2"> <div id="block-relatedpfforactivitypagescustom"> <div class="ewcms-page-section ecl-u-mb-2xl ecl-u-bg-neutral-40"> <div class="ecl-container ecl-u-pv-m"> <a id="paragraph_3113"></a> <div class="ecl"><p><strong>To find out more about the JRC's work on similar topics, explore the related JRC portfolios:</strong></p></div> </div> <div class="ecl-container ecl-u-pv-m"> <a id="paragraph_3114"></a> <div id="block-relatedpfforactivitypages" class="ecl-u-mt-l"> <div class="ecl-content-item-block"><div class="ecl-row"><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 "><article class="ecl-content-item" ><picture class="ecl-picture ecl-picture--zoom ecl-content-item__picture ecl-content-item__picture--large ecl-content-item__picture--left" data-ecl-picture-link ><img class="ecl-content-item__image" src="https://joint-research-centre.ec.europa.eu/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2023-01/29.cancer.and_.non-communicable.diseases_AdobeStock_333205216.jpeg.jpg?itok=YAan9eeU" alt="Woman with cancer during chemotherapy accompanied by a nurse recovering from illness in hospital." ></picture><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="/jrc-science-and-knowledge-activities/cancer-and-non-communicable-diseases_en" class="ecl-link ecl-link--standalone" >Cancer and non-communicable diseases</a></div><div class="ecl-content-block__description"><p>Tackling cancer and other non-communicable diseases.</p></div><div class="ecl-content-block__list-container"></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 "><article class="ecl-content-item" ><picture class="ecl-picture ecl-picture--zoom ecl-content-item__picture ecl-content-item__picture--large ecl-content-item__picture--left" data-ecl-picture-link ><img class="ecl-content-item__image" src="https://joint-research-centre.ec.europa.eu/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2023-01/11.sustainable.food_.systems_AdobeStock_273385943.jpg?itok=k1l30aKN" alt="Woman shopping in a bulk food store" ></picture><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="/jrc-science-and-knowledge-activities/sustainable-food-systems_en" class="ecl-link ecl-link--standalone" >Sustainable food systems</a></div><div class="ecl-content-block__description"><p>Transition to sustainable food systems in a European and global context.</p></div><div class="ecl-content-block__list-container"></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 last-item-column"><article class="ecl-content-item" ><picture class="ecl-picture ecl-picture--zoom ecl-content-item__picture ecl-content-item__picture--large ecl-content-item__picture--left" data-ecl-picture-link ><img class="ecl-content-item__image" src="https://joint-research-centre.ec.europa.eu/sites/default/files/styles/oe_theme_ratio_3_2_medium/avportal/P-034732/00-39.jpg?itok=Q_IJXoO_" alt="Westhof Bio farm, Friedrichsgabekoog and W枚hrden, Germany" ></picture><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="/scientific-activities-z/water-reuse_en" class="ecl-link ecl-link--standalone" >Water Reuse</a></div><div class="ecl-content-block__description"><p>The JRC provides scientific advice to help more water from cities be used for irrigation within the European Union.</p></div><div class="ecl-content-block__list-container"></div></div></article></div><div class="ecl-content-item-block__item contextual-region ecl-u-mb-l ecl-col-12 ecl-col-l-6 last-item-column last-item"><article class="ecl-content-item" ><picture class="ecl-picture ecl-picture--zoom ecl-content-item__picture ecl-content-item__picture--large ecl-content-item__picture--left" data-ecl-picture-link ><img class="ecl-content-item__image" src="https://joint-research-centre.ec.europa.eu/sites/default/files/styles/oe_theme_ratio_3_2_medium/public/2023-01/9.zero_.pollution_AdobeStock_370614434.jpg?itok=FBga7-ll" alt="Father with small children working outdoors in garden, sustainable lifestyle concept. " ></picture><div class="ecl-content-block ecl-content-item__content-block" data-ecl-auto-init="ContentBlock" data-ecl-content-block ><div class="ecl-content-block__title"data-ecl-title-link><a href="/jrc-science-and-knowledge-activities/zero-pollution_en" class="ecl-link ecl-link--standalone" >Zero pollution</a></div><div class="ecl-content-block__description"><p>Zero pollution for planetary health - Integrated responses.</p></div><div class="ecl-content-block__list-container"></div></div></article></div></div><div class="ecl-u-border-color-neutral ecl-u-border-width-1 ecl-u-border-top"></div><div class="ecl-row"><div class="ecl-content-item-block__button ecl-col-12"><div class="ecl-u-clearfix ecl-u-pv-m"><a href="/jrc-science-and-knowledge-activities/jrc-portfolios-z_en?prefLang=sl&f%5B0%5D=porfolios_portfolios%3A120&f%5B1%5D=porfolios_portfolios%3A122&f%5B2%5D=porfolios_portfolios%3A156&f%5B3%5D=source_ct_source_ct%3A161" class="ecl-link ecl-link--standalone ecl-link--icon" ><span class="ecl-link__label">See all JRC portfolios</span><svg class="ecl-icon ecl-icon--xs ecl-icon--rotate-180 ecl-link__icon" focusable="false" aria-hidden="true" ><use xlink:href="/themes/contrib/oe_theme/dist/ec/images/icons/sprites/icons.svg#arrow-left"></use></svg></a></div></div></div></div> </div> </div> </div> </div> </div> </div> </div> <div class="ecl-row"> <div class="ecl-col-s-12"> <div> <div id="block-ewcms-theme-socialshare"> <div class="ecl-social-media-share"> <p class="ecl-social-media-share__description"> Share this page </p> <script type="application/json">{"service":"share","version":"2.0","networks":["twitter","facebook","linkedin","email","more"],"display":"icons","stats":true,"selection":true}</script> </div> </div> </div> </div> </div> </div> </main> <div id="block-ewcms-theme-pagefeedbackform"> <script type="application/json">{"service":"dff","id":"BogbbnN2_dff_v2","lang":"en","version":"2.0"}</script> </div> <footer class="ecl-site-footer" 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