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carrier proteins</div> <p>The <b>latent TGF-beta binding protein</b>s (<b>LTBP</b>) are a family of <a href="/wiki/Carrier_protein" class="mw-redirect" title="Carrier protein">carrier proteins</a>.<sup id="cite_ref-pmid15611103_1-0" class="reference"><a href="#cite_note-pmid15611103-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid15381147_2-0" class="reference"><a href="#cite_note-pmid15381147-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>LTBP is a family of secreted multidomain proteins that were originally identified by their association with the latent form of <a href="/wiki/Transforming_growth_factor" title="Transforming growth factor">transforming growth factors</a>. They interact with a variety of <a href="/wiki/Extracellular_matrix" title="Extracellular matrix">extracellular matrix proteins</a> and may play a role in the regulation of <a href="/wiki/TGF_beta" class="mw-redirect" title="TGF beta">TGF beta</a> bioavailability. </p> <div class="mw-heading mw-heading2"><h2 id="Genes">Genes</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Latent_TGF-beta_binding_protein&action=edit&section=1" title="Edit section: Genes"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1216972533">.mw-parser-output .col-begin{border-collapse:collapse;padding:0;color:inherit;width:100%;border:0;margin:0}.mw-parser-output .col-begin-small{font-size:90%}.mw-parser-output .col-break{vertical-align:top;text-align:left}.mw-parser-output .col-break-2{width:50%}.mw-parser-output .col-break-3{width:33.3%}.mw-parser-output .col-break-4{width:25%}.mw-parser-output .col-break-5{width:20%}@media(max-width:720px){.mw-parser-output .col-begin,.mw-parser-output .col-begin>tbody,.mw-parser-output .col-begin>tbody>tr,.mw-parser-output .col-begin>tbody>tr>td{display:block!important;width:100%!important}.mw-parser-output .col-break{padding-left:0!important}}</style><div> <table class="col-begin" role="presentation"> <tbody><tr> <td class="col-break"> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above"><a href="/wiki/LTBP1_(gene)" title="LTBP1 (gene)">latent transforming growth factor beta binding protein 1</a></th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Symbol</th><td class="infobox-data" style="background-color: #eee"><a href="/wiki/LTBP1_(gene)" title="LTBP1 (gene)">LTBP1</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Alt. symbols</th><td class="infobox-data" style="background-color: #eee">TGF-beta1-BP-1</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/National_Center_for_Biotechnology_Information#Gene" title="National Center for Biotechnology Information">NCBI gene</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/gene?cmd=retrieve&dopt=default&list_uids=4052&rn=1">4052</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/HUGO_Gene_Nomenclature_Committee" title="HUGO Gene Nomenclature Committee">HGNC</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6714">6714</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Online_Mendelian_Inheritance_in_Man" title="Online Mendelian Inheritance in Man">OMIM</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://omim.org/entry/150390">150390</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/RefSeq" title="RefSeq">RefSeq</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/protein/NM_206943">NM_206943</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Swiss-Prot" class="mw-redirect" title="Swiss-Prot">UniProt</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q14766">Q14766</a></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Other data</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Locus</a></th><td class="infobox-data" style="background-color: #eee"><a href="/wiki/Chromosome_2_(human)" class="mw-redirect" title="Chromosome 2 (human)">Chr. 2</a> <i><a rel="nofollow" class="external text" href="https://omim.org/search/?index=geneMap&search=2p22">p22-p21</a></i></td></tr><tr><td colspan="2" class="infobox-full-data" style="background-color: #eee"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox mw-collapsible mw-collapsed" style="float:none; clear:none; margin:0; border-width:0; border-collapse:collapse; text-align:left; width:100%"><tbody><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Search for</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Structures</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://swissmodel.expasy.org/repository/uniprot/Q14766">Swiss-model</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Domains</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/interpro/protein/Q14766">InterPro</a></td></tr></tbody></table></td></tr></tbody></table> </td> <td class="col-break"> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above"><a href="/wiki/LTBP2" title="LTBP2">latent transforming growth factor beta binding protein 2</a></th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Symbol</th><td class="infobox-data" style="background-color: #eee"><a href="/wiki/LTBP2" title="LTBP2">LTBP2</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Alt. symbols</th><td class="infobox-data" style="background-color: #eee">LTBP3, C14orf141</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/National_Center_for_Biotechnology_Information#Gene" title="National Center for Biotechnology Information">NCBI gene</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/gene?cmd=retrieve&dopt=default&list_uids=4053&rn=1">4053</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/HUGO_Gene_Nomenclature_Committee" title="HUGO Gene Nomenclature Committee">HGNC</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6715">6715</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Online_Mendelian_Inheritance_in_Man" title="Online Mendelian Inheritance in Man">OMIM</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://omim.org/entry/602091">602091</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/RefSeq" title="RefSeq">RefSeq</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/protein/NM_000428">NM_000428</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Swiss-Prot" class="mw-redirect" title="Swiss-Prot">UniProt</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q14767">Q14767</a></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Other data</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Locus</a></th><td class="infobox-data" style="background-color: #eee"><a href="/wiki/Chromosome_14_(human)" class="mw-redirect" title="Chromosome 14 (human)">Chr. 14</a> <i><a rel="nofollow" class="external text" href="https://omim.org/search/?index=geneMap&search=14q24.3">q24.3</a></i></td></tr><tr><td colspan="2" class="infobox-full-data" style="background-color: #eee"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox mw-collapsible mw-collapsed" style="float:none; clear:none; margin:0; border-width:0; border-collapse:collapse; text-align:left; width:100%"><tbody><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Search for</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Structures</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://swissmodel.expasy.org/repository/uniprot/Q14767">Swiss-model</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Domains</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/interpro/protein/Q14767">InterPro</a></td></tr></tbody></table></td></tr></tbody></table> </td> <td class="col-break"> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above"><a href="/wiki/LTBP3" title="LTBP3">latent transforming growth factor beta binding protein 3</a></th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Symbol</th><td class="infobox-data" style="background-color: #eee"><a href="/wiki/LTBP3" title="LTBP3">LTBP3</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Alt. symbols</th><td class="infobox-data" style="background-color: #eee">LTBP2</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/National_Center_for_Biotechnology_Information#Gene" title="National Center for Biotechnology Information">NCBI gene</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/gene?cmd=retrieve&dopt=default&list_uids=4054&rn=1">4054</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/HUGO_Gene_Nomenclature_Committee" title="HUGO Gene Nomenclature Committee">HGNC</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6716">6716</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Online_Mendelian_Inheritance_in_Man" title="Online Mendelian Inheritance in Man">OMIM</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://omim.org/entry/602090">602090</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/RefSeq" title="RefSeq">RefSeq</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/protein/NM_021070">NM_021070</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Swiss-Prot" class="mw-redirect" title="Swiss-Prot">UniProt</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q9NS15">Q9NS15</a></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Other data</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Locus</a></th><td class="infobox-data" style="background-color: #eee"><a href="/wiki/Chromosome_11_(human)" class="mw-redirect" title="Chromosome 11 (human)">Chr. 11</a> <i><a rel="nofollow" class="external text" href="https://omim.org/search/?index=geneMap&search=11q12">q12</a></i></td></tr><tr><td colspan="2" class="infobox-full-data" style="background-color: #eee"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox mw-collapsible mw-collapsed" style="float:none; clear:none; margin:0; border-width:0; border-collapse:collapse; text-align:left; width:100%"><tbody><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Search for</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Structures</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://swissmodel.expasy.org/repository/uniprot/Q9NS15">Swiss-model</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Domains</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/interpro/protein/Q9NS15">InterPro</a></td></tr></tbody></table></td></tr></tbody></table> </td> <td class="col-break"> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above">latent transforming growth factor beta binding protein 4</th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Symbol</th><td class="infobox-data" style="background-color: #eee">LTBP4</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Alt. symbols</th><td class="infobox-data" style="background-color: #eee">LTBP-4, LTBP-4L</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/National_Center_for_Biotechnology_Information#Gene" title="National Center for Biotechnology Information">NCBI gene</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/gene?cmd=retrieve&dopt=default&list_uids=8425&rn=1">8425</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/HUGO_Gene_Nomenclature_Committee" title="HUGO Gene Nomenclature Committee">HGNC</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6717">6717</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Online_Mendelian_Inheritance_in_Man" title="Online Mendelian Inheritance in Man">OMIM</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://omim.org/entry/604710">604710</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/RefSeq" title="RefSeq">RefSeq</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/protein/NM_003573">NM_003573</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Swiss-Prot" class="mw-redirect" title="Swiss-Prot">UniProt</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q8N2S1">Q8N2S1</a></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Other data</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Locus</a></th><td class="infobox-data" style="background-color: #eee"><a href="/wiki/Chromosome_19_(human)" class="mw-redirect" title="Chromosome 19 (human)">Chr. 19</a> <i><a rel="nofollow" class="external text" href="https://omim.org/search/?index=geneMap&search=19q13.1">q13.1-13.2</a></i></td></tr><tr><td colspan="2" class="infobox-full-data" style="background-color: #eee"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox mw-collapsible mw-collapsed" style="float:none; clear:none; margin:0; border-width:0; border-collapse:collapse; text-align:left; width:100%"><tbody><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Search for</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Structures</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://swissmodel.expasy.org/repository/uniprot/Q8N2S1">Swiss-model</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Domains</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/interpro/protein/Q8N2S1">InterPro</a></td></tr></tbody></table></td></tr></tbody></table> <p>  </p> </td></tr></tbody></table></div> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Latent_TGF-beta_binding_protein&action=edit&section=2" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-pmid15611103-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid15611103_1-0">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFRifkin_DB2005" class="citation journal cs1">Rifkin DB (March 2005). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.R400029200">"Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability"</a>. <i>J. Biol. Chem</i>. <b>280</b> (9): 7409–12. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.R400029200">10.1074/jbc.R400029200</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15611103">15611103</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Biol.+Chem.&rft.atitle=Latent+transforming+growth+factor-beta+%28TGF-beta%29+binding+proteins%3A+orchestrators+of+TGF-beta+availability&rft.volume=280&rft.issue=9&rft.pages=7409-12&rft.date=2005-03&rft_id=info%3Adoi%2F10.1074%2Fjbc.R400029200&rft_id=info%3Apmid%2F15611103&rft.au=Rifkin+DB&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.R400029200&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALatent+TGF-beta+binding+protein" class="Z3988"></span></span> </li> <li id="cite_note-pmid15381147-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid15381147_2-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFTodorovicJurukovskiChenFontana2005" class="citation journal cs1">Todorovic V, Jurukovski V, Chen Y, Fontana L, Dabovic B, Rifkin DB (January 2005). "Latent TGF-beta binding proteins". <i>Int. J. Biochem. Cell Biol</i>. <b>37</b> (1): 38–41. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.biocel.2004.03.011">10.1016/j.biocel.2004.03.011</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15381147">15381147</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Int.+J.+Biochem.+Cell+Biol.&rft.atitle=Latent+TGF-beta+binding+proteins&rft.volume=37&rft.issue=1&rft.pages=38-41&rft.date=2005-01&rft_id=info%3Adoi%2F10.1016%2Fj.biocel.2004.03.011&rft_id=info%3Apmid%2F15381147&rft.aulast=Todorovic&rft.aufirst=V&rft.au=Jurukovski%2C+V&rft.au=Chen%2C+Y&rft.au=Fontana%2C+L&rft.au=Dabovic%2C+B&rft.au=Rifkin%2C+DB&rfr_id=info%3Asid%2Fen.wikipedia.org%3ALatent+TGF-beta+binding+protein" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Latent_TGF-beta_binding_protein&action=edit&section=3" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?name=Latent+TGF-beta+Binding+Proteins">Latent+TGF-beta+Binding+Proteins</a> at the U.S. National Library of Medicine <a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">Medical Subject Headings</a> (MeSH)</li> <li><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/Q14766">PDBe-KB</a> provides an overview of all the structure information available in the PDB for Human Latent-transforming growth factor beta-binding protein 1</li></ul> <p><br /> </p> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · ";font-weight:bold}.mw-parser-output .hlist dd:last-child::after,.mw-parser-output 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href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Carrier_proteins" title="Template:Carrier proteins"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Carrier_proteins" title="Template talk:Carrier proteins"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Carrier_proteins" title="Special:EditPage/Template:Carrier proteins"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Proteins:_carrier_proteins" style="font-size:114%;margin:0 4em"><a href="/wiki/Protein" title="Protein">Proteins</a>: <a href="/wiki/Carrier_protein" class="mw-redirect" title="Carrier protein">carrier proteins</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Fatty_acid-binding_protein" title="Fatty acid-binding protein">Fatty acid</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/FABP1" title="FABP1">FABP1</a></li> <li><a href="/wiki/FABP2" title="FABP2">FABP2</a></li> <li><a href="/wiki/Heart-type_fatty_acid_binding_protein" title="Heart-type fatty acid binding protein">FABP3</a></li> <li><a href="/wiki/Adipocyte_protein_2" title="Adipocyte protein 2">FABP4</a></li> <li><a href="/wiki/FABP5" title="FABP5">FABP5</a></li> <li><a href="/wiki/FABP6" title="FABP6">FABP6</a></li> <li><a href="/wiki/FABP7" title="FABP7">FABP7</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Hormone</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Peptide_hormone" title="Peptide hormone">peptide hormone</a>: <a href="/wiki/Follistatin" title="Follistatin">Follistatin</a></li> <li><a href="/wiki/Growth_hormone-binding_protein" title="Growth hormone-binding protein">Growth hormone binding protein</a></li> <li><a href="/wiki/Insulin-like_growth_factor-binding_protein" title="Insulin-like growth factor-binding protein">Insulin-like growth factor binding protein</a> <ul><li><a href="/wiki/IGFBP1" title="IGFBP1">IGFBP1</a></li> <li><a href="/wiki/IGFBP2" title="IGFBP2">IGFBP2</a></li> <li><a href="/wiki/IGFBP3" title="IGFBP3">IGFBP3</a></li> <li><a href="/wiki/IGFBP4" title="IGFBP4">IGFBP4</a></li> <li><a href="/wiki/IGFBP5" title="IGFBP5">IGFBP5</a></li> <li><a href="/wiki/IGFBP6" title="IGFBP6">IGFBP6</a></li> <li><a href="/wiki/IGFBP7" title="IGFBP7">IGFBP7</a></li></ul></li> <li><a href="/wiki/Neurophysins" title="Neurophysins">Neurophysins</a> <ul><li><a href="/wiki/Neurophysin_I" title="Neurophysin I">Neurophysin I</a></li> <li><a href="/wiki/Neurophysin_II" title="Neurophysin II">II</a></li></ul></li></ul> <ul><li><a href="/wiki/Steroid_hormone" title="Steroid hormone">steroid hormone</a>: <a href="/wiki/Sex_hormone-binding_globulin" title="Sex hormone-binding globulin">Sex hormone binding globulin</a>/<a href="/wiki/Androgen-binding_protein" class="mw-redirect" title="Androgen-binding protein">Androgen binding protein</a></li> <li><a href="/wiki/Transcortin" title="Transcortin">Transcortin</a></li> <li><a href="/wiki/Thyroxine-binding_globulin" title="Thyroxine-binding globulin">Thyroxine-binding globulin</a></li> <li><a href="/wiki/Transthyretin" title="Transthyretin">Transthyretin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Metal/element</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i>calcium</i> <ul><li><a href="/wiki/Calcium-binding_protein" title="Calcium-binding protein">Calcium-binding protein</a></li> <li><a href="/wiki/Calmodulin-binding_proteins" title="Calmodulin-binding proteins">Calmodulin-binding proteins</a></li></ul></li> <li><i>copper</i> <ul><li><a href="/wiki/Ceruloplasmin" title="Ceruloplasmin">Ceruloplasmin</a></li></ul></li> <li><i>iron</i> <ul><li><a href="/wiki/Iron-binding_proteins" title="Iron-binding proteins">Iron-binding proteins</a></li> <li><a href="/wiki/Transferrin_receptor" title="Transferrin receptor">Transferrin receptor</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Vitamin</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Retinol_binding_protein" class="mw-redirect" title="Retinol binding protein">Retinol binding protein</a> <ul><li><a href="/wiki/RBP1" title="RBP1">1</a></li> <li><a href="/wiki/RBP2" title="RBP2">2</a></li> <li><a href="/wiki/RBP3" title="RBP3">3</a></li> <li><a href="/wiki/Retinol_binding_protein_4" title="Retinol binding protein 4">4</a></li></ul></li> <li><a href="/wiki/Transcobalamin" title="Transcobalamin">Transcobalamin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Biological_pigment" title="Biological pigment">Pigment</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Light-harvesting_complexes_of_green_plants" title="Light-harvesting complexes of green plants">Plant Light-Harvesting Complex</a></li> <li><a href="/wiki/Orange_carotenoid_N-terminal_domain" title="Orange carotenoid N-terminal domain">Orange Carotenoid Protein</a></li> <li><a href="/wiki/Phycobiliprotein" title="Phycobiliprotein">Phycobiliprotein</a></li> <li><a href="/wiki/Photosynthetic_reaction_centre_protein_family" title="Photosynthetic reaction centre protein family">Photosynthetic Reaction Centers</a></li> <li><a href="/wiki/Phytochrome" title="Phytochrome">Phytochrome</a></li> <li><a href="/wiki/Rhodopsin" title="Rhodopsin">Rhodopsin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Other</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Acyl_carrier_protein" title="Acyl carrier protein">Acyl carrier protein</a></li> <li><a href="/wiki/Signal_transducing_adaptor_protein" title="Signal transducing adaptor protein">Adaptor protein</a></li> <li><a href="/wiki/Cholesterylester_transfer_protein" class="mw-redirect" title="Cholesterylester transfer protein">Cholesterylester transfer protein</a></li> <li><a href="/wiki/F-box_protein" title="F-box protein">F-box protein</a></li> <li><a href="/wiki/G_protein" title="G protein">GTP-binding protein</a></li> <li><a class="mw-selflink selflink">Latent TGF-beta binding protein</a></li> <li><a href="/wiki/Major_urinary_proteins" title="Major urinary proteins">Major urinary proteins</a></li> <li><a href="/wiki/Membrane_transport_protein" title="Membrane transport protein">Membrane transport protein</a></li> <li><a href="/wiki/Odorant_binding_protein" class="mw-redirect" title="Odorant binding protein">Odorant binding protein</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Cell_signaling:_TGFβ_signaling_pathway" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:TGF_beta_signaling" title="Template:TGF beta signaling"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:TGF_beta_signaling" title="Template talk:TGF beta signaling"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:TGF_beta_signaling" title="Special:EditPage/Template:TGF beta signaling"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Cell_signaling:_TGFβ_signaling_pathway" style="font-size:114%;margin:0 4em"><a href="/wiki/Cell_signaling" title="Cell signaling">Cell signaling</a>: <a href="/wiki/TGF%CE%B2_signaling_pathway" class="mw-redirect" title="TGFβ signaling pathway">TGFβ signaling pathway</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Transforming_growth_factor_beta_superfamily" title="Transforming growth factor beta superfamily">TGF beta superfamily of ligands</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Ligand of <a href="/wiki/Activin_receptor" title="Activin receptor">ACVR</a> or <a href="/wiki/TGF_beta_receptor" title="TGF beta receptor">TGFBR</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Transforming_growth_factor_beta" title="Transforming growth factor beta">TGF beta family</a> <ul><li><a href="/wiki/TGF_beta_1" title="TGF beta 1">TGF-β1</a></li> <li><a href="/wiki/TGF_beta_2" title="TGF beta 2">TGF-β2</a></li> <li><a href="/wiki/TGF_beta_3" class="mw-redirect" title="TGF beta 3">TGF-β3</a></li></ul></li> <li><a href="/wiki/Activin_and_inhibin" title="Activin and inhibin">Activin and inhibin</a> <ul><li><a href="/wiki/INHA" title="INHA">INHA</a></li> <li><a href="/wiki/INHBA" title="INHBA">INHBA</a></li> <li><a href="/wiki/INHBB" title="INHBB">INHBB</a></li> <li><a href="/wiki/INHBC" title="INHBC">INHBC</a></li></ul></li> <li><a href="/wiki/NODAL" class="mw-redirect" title="NODAL">Nodal</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Ligand of <a href="/wiki/Bone_morphogenetic_protein_receptor" title="Bone morphogenetic protein receptor">BMPR</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Bone_morphogenetic_protein" title="Bone morphogenetic protein">Bone morphogenetic proteins</a> <ul><li><a href="/wiki/Bone_morphogenetic_protein_2" title="Bone morphogenetic protein 2">BMP2</a></li> <li><a href="/wiki/Bone_morphogenetic_protein_3" title="Bone morphogenetic protein 3">BMP3</a></li> <li><a href="/wiki/Bone_morphogenetic_protein_4" title="Bone morphogenetic protein 4">BMP4</a></li> <li><a href="/wiki/Bone_morphogenetic_protein_5" title="Bone morphogenetic protein 5">BMP5</a></li> <li><a href="/wiki/Bone_morphogenetic_protein_6" title="Bone morphogenetic protein 6">BMP6</a></li> <li><a href="/wiki/Bone_morphogenetic_protein_7" title="Bone morphogenetic protein 7">BMP7</a></li> <li><a href="/wiki/Bone_morphogenetic_protein_8A" title="Bone morphogenetic protein 8A">BMP8a</a></li> <li><a href="/wiki/Bone_morphogenetic_protein_8b" class="mw-redirect" title="Bone morphogenetic protein 8b">BMP8b</a></li> <li><a href="/wiki/Bone_morphogenetic_protein_10" title="Bone morphogenetic protein 10">BMP10</a></li> <li><a href="/wiki/Bone_morphogenetic_protein_15" title="Bone morphogenetic protein 15">BMP15</a></li></ul></li> <li><a href="/wiki/Growth_differentiation_factor" title="Growth differentiation factor">Growth differentiation factors</a> <ul><li><a href="/wiki/GDF1" title="GDF1">GDF1</a></li> <li><a href="/wiki/GDF2" title="GDF2">GDF2</a></li> <li><a href="/wiki/GDF3" title="GDF3">GDF3</a></li> <li><a href="/wiki/GDF5" title="GDF5">GDF5</a></li> <li><a href="/wiki/GDF6" title="GDF6">GDF6</a></li> <li><a href="/wiki/GDF7" title="GDF7">GDF7</a></li> <li><a href="/wiki/Myostatin" title="Myostatin">Myostatin/GDF8</a></li> <li><a href="/wiki/Growth_differentiation_factor-9" title="Growth differentiation factor-9">GDF9</a></li> <li><a href="/wiki/GDF10" title="GDF10">GDF10</a></li> <li><a href="/wiki/GDF11" title="GDF11">GDF11</a></li> <li><a href="/wiki/GDF15" title="GDF15">GDF15</a></li></ul></li> <li><a href="/wiki/Anti-M%C3%BCllerian_hormone" title="Anti-Müllerian hormone">Anti-müllerian hormone</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/TGF_beta_receptors" class="mw-redirect" title="TGF beta receptors">TGF beta receptors</a><br />(<a href="/wiki/Activin_receptor" title="Activin receptor">Activin</a>, <a href="/wiki/Bone_morphogenetic_protein_receptors" class="mw-redirect" title="Bone morphogenetic protein receptors">BMP</a>, <a href="/wiki/TGF-beta_receptor_family" title="TGF-beta receptor family">family</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">TGFBR1:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Activin_type_1_receptors" title="Activin type 1 receptors">Activin type 1 receptors</a> <ul><li><a href="/wiki/ACVR1" title="ACVR1">ACVR1</a></li> <li><a href="/wiki/ACVR1B" title="ACVR1B">ACVR1B</a></li> <li><a href="/wiki/ACVR1C" title="ACVR1C">ACVR1C</a></li></ul></li> <li><a href="/wiki/ACVRL1" title="ACVRL1">ACVRL1</a></li> <li><a href="/wiki/Bone_morphogenetic_protein_receptor,_type_1" title="Bone morphogenetic protein receptor, type 1">BMPR1</a> <ul><li><a href="/wiki/BMPR1A" title="BMPR1A">BMPR1A</a></li> <li><a href="/wiki/BMPR1B" title="BMPR1B">BMPR1B</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">TGFBR2:</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Activin_type_2_receptors" title="Activin type 2 receptors">Activin type 2 receptors</a> <ul><li><a href="/wiki/ACVR2A" title="ACVR2A">ACVR2A</a></li> <li><a href="/wiki/ACVR2B" title="ACVR2B">ACVR2B</a></li></ul></li> <li><a href="/wiki/Anti-M%C3%BCllerian_hormone_receptor" title="Anti-Müllerian hormone receptor">AMHR2</a></li> <li><a href="/wiki/BMPR2" title="BMPR2">BMPR2</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">TGFBR3:</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Betaglycan" class="mw-redirect" title="Betaglycan">betaglycan</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Signal_transduction" title="Signal transduction">Transducers</a>/<a href="/wiki/SMAD_(protein)" title="SMAD (protein)">SMAD</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/R-SMAD" title="R-SMAD">R-SMAD</a> (<a href="/wiki/Mothers_against_decapentaplegic_homolog_1" title="Mothers against decapentaplegic homolog 1">SMAD1</a></li> <li><a href="/wiki/Mothers_against_decapentaplegic_homolog_2" title="Mothers against decapentaplegic homolog 2">SMAD2</a></li> <li><a href="/wiki/Mothers_against_decapentaplegic_homolog_3" title="Mothers against decapentaplegic homolog 3">SMAD3</a></li> <li><a href="/wiki/Mothers_against_decapentaplegic_homolog_5" title="Mothers against decapentaplegic homolog 5">SMAD5</a></li> <li><a href="/wiki/Mothers_against_decapentaplegic_homolog_9" title="Mothers against decapentaplegic homolog 9">SMAD9</a>)</li> <li><a href="/wiki/I-SMAD" title="I-SMAD">I-SMAD</a> (<a href="/wiki/Mothers_against_decapentaplegic_homolog_6" title="Mothers against decapentaplegic homolog 6">SMAD6</a></li> <li><a href="/wiki/Mothers_against_decapentaplegic_homolog_7" title="Mothers against decapentaplegic homolog 7">SMAD7</a>)</li> <li><a href="/wiki/Mothers_against_decapentaplegic_homolog_4" title="Mothers against decapentaplegic homolog 4">SMAD4</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/TGF_beta_signaling_pathway#Ligand_agonists.2Fantagonists" title="TGF beta signaling pathway">Ligand inhibitors</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cerberus_(protein)" title="Cerberus (protein)">Cerberus</a></li> <li><a href="/wiki/Chordin" title="Chordin">Chordin</a></li> <li><a href="/wiki/Decorin" title="Decorin">Decorin</a></li> <li><a href="/wiki/Follistatin" title="Follistatin">Follistatin</a></li> <li><a href="/wiki/Gremlin_(protein)" title="Gremlin (protein)">Gremlin</a></li> <li><a href="/wiki/Lefty_(protein)" title="Lefty (protein)">Lefty</a></li> <li><a class="mw-selflink selflink">LTBP1</a></li> <li><a href="/wiki/Noggin_(protein)" title="Noggin (protein)">Noggin</a></li> <li><a href="/wiki/Poly(A)-specific_ribonuclease" title="Poly(A)-specific ribonuclease">PARN</a></li> <li><a href="/wiki/Thrombospondin_1" title="Thrombospondin 1">THBS1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Co-receptor" title="Co-receptor">Coreceptors</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/BAMBI" title="BAMBI">BAMBI</a></li> <li><a href="/wiki/Cripto" title="Cripto">Cripto</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Other</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Zinc_finger_FYVE_domain-containing_protein_9" title="Zinc finger FYVE domain-containing protein 9">SARA</a></li></ul> </div></td></tr></tbody></table></div> <p><br /> </p> <style data-mw-deduplicate="TemplateStyles:r1012311289">.mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-style:italic}.mw-parser-output .asbox-note{font-size:smaller}.mw-parser-output .asbox .navbar{position:absolute;top:-0.75em;right:1em;display:none}</style><div role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span 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