Pala Cell Sorter and Single Cell Dispenser (NI006) by Bio-Techne

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<div class="sub-menu-header"> Instruments<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/brands/proteinsimple" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3281">ProteinSimple Instruments</a> <a href="/instruments/ice" title="Our capillary electrophoresis instruments (icIEF and CE-SDS) provide reproducible quantitative analysis for thorough therapeutic protein characterization." class="dropdown-item text-wrap" data-drupal-link-system-path="node/256">iCE Maurice</a> <a href="/instruments/imagers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/536">Imagers</a> <a href="/instruments/luminex" class="dropdown-item text-wrap" data-drupal-link-system-path="node/241">Luminex</a> <a href="/instruments/micro-flow-imaging" class="dropdown-item text-wrap" data-drupal-link-system-path="node/526">Micro-Flow Imaging</a> <a href="/instruments/simple-plex" class="dropdown-item text-wrap" data-drupal-link-system-path="node/541">Simple Plex Ella</a> <a href="/instruments/simple-western" class="dropdown-item text-wrap" data-drupal-link-system-path="node/521">Simple Western</a> <a href="/instruments/single-cell-dispensers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6361">Single Cell Dispensers</a> <a href="/instruments/single-cell-western" class="dropdown-item text-wrap" data-drupal-link-system-path="node/531">Single-Cell Western</a> <a href="/instruments" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6731">View All Instruments</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Applications<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/methods/bioprocessing" class="dropdown-item text-wrap">Bioprocessing</a> <a href="/applications/crispr" class="dropdown-item text-wrap" 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data-drupal-link-system-path="node/1452">Organoid and 3-D Culture</a> <a href="/research-areas/stem-cells" class="dropdown-item text-wrap" data-drupal-link-system-path="node/161">Stem Cells</a> <a href="/research-areas/targeted-protein-degradation" class="dropdown-item text-wrap" data-drupal-link-system-path="node/376">Targeted Protein Degradation</a> <a href="/research-areas" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6741">View All Research Areas</a> </div> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-therapeutic-manufacturing" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Therapeutic Manufacturing <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-therapeutic-manufacturing" aria-labelledby="navbarDropdown-therapeutic-manufacturing"> <div class="row"> <div class="col 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Proteins</a> <a href="/gmp-products/gmp-small-molecules" class="dropdown-item text-wrap" data-drupal-link-system-path="node/366">GMP Small Molecules</a> <a href="/gmp-products/gmp-antibodies" class="dropdown-item text-wrap" data-drupal-link-system-path="node/13266">GMP Antibodies</a> <a href="/gmp-products/gmp-capabilities" class="dropdown-item text-wrap" title="GMP Capabilities" data-drupal-link-system-path="node/1071">GMP Capabilities</a> <a href="/gmp-products/ruo-to-gmp" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3421">Transition to GMP </a> <a href="/gmp-products/loa-request" class="dropdown-item text-wrap" data-drupal-link-system-path="node/13326">DMF/LOA Request</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Instruments<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/brands/proteinsimple" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3281">ProteinSimple Instruments</a> <a href="/instruments/ice" class="dropdown-item text-wrap" data-drupal-link-system-path="node/256">iCE Maurice</a> <a href="/instruments/imagers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/536">Imagers</a> <a href="/instruments/luminex" class="dropdown-item text-wrap" data-drupal-link-system-path="node/241">Luminex</a> <a href="/instruments/micro-flow-imaging" class="dropdown-item text-wrap" data-drupal-link-system-path="node/526">Micro-Flow Imaging</a> <a href="/instruments/simple-plex" class="dropdown-item text-wrap" data-drupal-link-system-path="node/541">Simple Plex Ella</a> <a href="/instruments/simple-western" class="dropdown-item text-wrap" data-drupal-link-system-path="node/521">Simple Western</a> <a href="/instruments/single-cell-dispensers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6361">Single Cell Dispensers</a> <a href="/instruments/single-cell-western" class="dropdown-item text-wrap" data-drupal-link-system-path="node/531">Single Cell Western</a> <a href="/instruments" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6731">View All Instruments</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Applications<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/methods/bioprocessing" class="dropdown-item text-wrap">Bioprocessing</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Research Areas<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/research-areas/cell-and-gene-therapy" class="dropdown-item text-wrap" data-drupal-link-system-path="node/51">Cell & Gene Therapy</a> <a href="/applications/immuno-oncology-clinical" class="dropdown-item text-wrap" data-drupal-link-system-path="node/2066">Immuno-Oncology</a> </div> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-diagnostics" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Diagnostics <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-diagnostics" aria-labelledby="navbarDropdown-diagnostics"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Controls & Reagents<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/diagnostics/clinical-quality-controls" class="dropdown-item text-wrap" data-drupal-link-system-path="node/7606">Clinical Quality Controls</a> <a href="/diagnostics/molecular-quality-controls" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5596">Molecular Controls</a> <a href="/diagnostics/controls-reagents/rnascope-ish-probe-high-risk-hpv" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5981">RNAscope™ ISH Probe High Risk HPV</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Kits<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/diagnostics/amplidex-genetic-testing-kits" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5581">Genetics</a> <a href="/diagnostics/quantidex-oncology-testing-kits" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5586">Oncology</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Technology<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/diagnostics/exosome" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5486">Exosome Platform</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> OEM Services<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/diagnostics/ivd-assay-development" class="dropdown-item text-wrap" data-drupal-link-system-path="node/10881">IVD Assay Development</a> <a href="/diagnostics/ivd-contract-manufacturing" class="dropdown-item text-wrap" data-drupal-link-system-path="node/7381">IVD Contract Manufacturing</a> <a href="/diagnostics/molecular-quality-controls/oem-and-commercial-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6781">Molecular Diagnostic OEM Services</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Companion Diagnostics<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/diagnostics/companion-diagnostics" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5631">Companion Diagnostics Services</a> <a href="/diagnostics/companion-diagnostics/multiomics" class="dropdown-item text-wrap" data-drupal-link-system-path="node/10616">Multiomics Platform</a> </div> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-services" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Services <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-services" aria-labelledby="navbarDropdown-services"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Custom Quotes<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/services/bulk-quotes" class="dropdown-item text-wrap" data-drupal-link-system-path="services/bulk-quotes">Bulk Quote Discounts</a> <a href="/services/custom-formulation" class="dropdown-item text-wrap" data-drupal-link-system-path="services/custom-formulation">Custom Formulation Quotes</a> <a href="/reagents/rnascope-ish-technology/probes/custom" class="dropdown-item text-wrap" data-drupal-link-system-path="node/12571">RNAscope Custom Probe Design Quote</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Custom Services<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/services/custom-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1891">All Custom Services</a> <a href="/services/custom-antibody-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/906">Custom Antibody Services</a> <a href="/services/custom-cell-and-gene-therapy-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1281">Custom Cell & Gene Therapy Services</a> <a href="/services/custom-compound-library-service" class="dropdown-item text-wrap" data-drupal-link-system-path="node/2126">Custom Compound Library Services</a> <a href="/services/custom-elisa-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/261">Custom ELISA Services</a> <a href="/services/gene-engineering-services-tcbuster" class="dropdown-item text-wrap" title="Gene Engineering Services: Bio-Techne" data-drupal-link-system-path="node/1136">Custom Gene Engineering Services</a> <a href="/services/custom-luminex-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/271">Custom Luminex Services</a> <a href="/services/custom-protein-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1441">Custom Protein Services</a> <a href="/services/custom-simple-plex-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6296">Custom Simple Plex Services</a> <a href="/services/custom-targeted-protein-degradation-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/861">Custom Targeted Protein Degradation Services</a> <a href="/services/professional-assay-services-rnascope" class="dropdown-item text-wrap" data-drupal-link-system-path="node/12306">RNAscope Professional Assay Services</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Instrument Services<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/services/certified-service-provider-program" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5446">Certified Service Provider (CSP) Program</a> <a href="/resources/instrument-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5471">Contract Services</a> <a href="/services/instrument-services/simple-western-service-plans" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3181">Simple Western Service Plans</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Licensing<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/services/biotechnology-licensing-partnering" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1101">Biotechnology Licensing and Partnering</a> </div> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-resources" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Resources <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-resources" aria-labelledby="navbarDropdown-resources"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Product & Instrument Tools<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/resources/cofa-finder-tool" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/cofa-finder-tool">Certificate of Analysis (COA) Finder Tool</a> <a href="/resources/calculators" class="dropdown-item text-wrap" data-drupal-link-system-path="node/7416">Calculators</a> <a href="/resources/flow-cytometry-panel-builder" class="dropdown-item text-wrap" data-drupal-link-system-path="node/8821">Flow Cytometry Panel Builder</a> <a href="/luminex-assay-customization-tool" class="dropdown-item text-wrap" data-drupal-link-system-path="luminex-assay-customization-tool">Luminex Assay Customization Tool</a> <a href="/resources/product-insert-lookup-tool" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/product-insert-lookup-tool">Product Insert Lookup Tool</a> <a href="/resources/rnascope-citations" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/rnascope-citations">RNAscope Citations</a> <a href="/resources/simple-plex-panel-builder" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/simple-plex-panel-builder">Simple Plex Panel Builder</a> <a href="/resources/simple-western-kit-builder" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/simple-western-kit-builder">Simple Western Kit Builder</a> <a href="/resources/simple-western-antibody-database" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/simple-western-antibody-database">Simple Western Antibody Database</a> <a href="/resources/single-cell-western-antibody-database" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/single-cell-western-antibody-database">Single-Cell Western Antibody Database</a> <a href="/resources/spectra-viewer" class="dropdown-item text-wrap" 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<div class="highlighted"> <aside class="container section clearfix" role="complementary"> <div> </div> </aside> </div> <div id="main" class="container-fluid container-wide "> <div class="row"> <div class="col-md-12"> <div> <div id="block-bio-techne-global-breadcrumbs" class="system_breadcrumb_block"> <nav role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> Products </li> <li> <a href="/search?keywords=Cell%20Sorting%20and%20Single%20Cell%20Dispensing&category_attr=Cell%20Sorting%20and%20Single%20Cell%20Dispensing">Cell Sorting and Single Cell Dispensing</a> </li> <li> Pala Cell Sorter and Single Cell Dispenser (NI006) </li> </ol> </nav> </div> </div> </div> </div> <div class="row"> <div class="col-md-12"> <main> <section class="section"> <div> <div id="block-bio-techne-global-content" class="system_main_block"> <div class="top_region"><div class="o___product-summary mb-3 border-bottom"><div id="pp-page-title-brand-wrapper"> <div id="header-subheader" data-section="section-base--header-subheader"> <div class="row" id="pp-page-title-brand-wrapper"> <div class="col-lg-9 col-md-12"> <h1 class="font-weight-bold"> Pala Cell Sorter and Single Cell Dispenser </h1> <h2 class="font-weight-normal h4"> Bio-Techne <span id="product-code"> | Catalog # <span class="font-weight-bold">NI006</span> </span> </h2> <div id="pp-reviews-citations-row"> <div id="header_left" class="row"> <div class="col-auto d-flex align-self-center"> <div> </div> </div> </div> </div> <div id="new_version_available"> </div> </div> <div class="col-lg-3 col-md-12"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/logos/bio-techne.svg" alt="Bio-Techne" class="d-flex h-100 w-100"> </div> </div> </div> </div> </div> <div class="row mb-4"><div class="col-xl-3 order-xl-first" id="image_wrapper"><div id="images_summary"><article class="product-data-wrapper"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand="biotechne"> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-1052024105813.jpg" alt="Pala Cell Sorter and Single Cell Dispenser" title="Pala - Cell Sorting and Single Cell Dispensing" data-caption="The Bio-techne Pala is a versatile and gentle benchtop cell sorter and single cell dispenser. Equipped with 2 excitation lasers, this instrument is capable of detecting and sorting cells utilizing a wide range of fluorescent molecules and stains. Pala combines high single cell dispensing accuracy in both 96 & 384 well plates and gentle bulk sorting capabilities." data-badges="" data-application="N/A" width="250" height="250" fetchpriority=high as=image class="search_result_thumbnail_image" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> <span class="image-count-text align-middle">(2)</span> </div> </div> </div> <i data-src="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-1052024125215.png" data-alt="Gentle cell handling induces less stress response changes" title="How does the Pala Cell Sorter and Single Cell Dispenser compare to traditional FACS and limited dilution with sensitive cell lines?" data-caption="The Pala system is gentle and uses very low pressure (<2 psi) for cell sorting. In contrast, conventional FACS instruments use relatively high pressures (30-70 psi), which can be damaging for sensitive cells, resulting in reduced cell viability. The figure on the left shows a comparison of cellular stress response genes between cells isolated using a FACS instrument vs. using Bio-Techne's gentle cell sorting technology. Cells sorted with a FACS instrument showed induction of cellular stress response genes such as Ubiquitin C (Ubc), while cells sorted using Bio-Techne's technology show much lower expression of stress response genes. Limited dilution, on the other hand, is a gentle technique but does not yield high rates of single cell clones and has no fluorescence sorting capabilities resulting in laborious screening and high experimental failure rates." data-badges="" data-application="N/A" data-width="250" data-height="250" class="none"></i> </div> </div> </article> </div> </div> <div class="col-xl-9 order-xl-first" id="key_benefits_buttoon_wrapper"> <h3>Bulk and Single Cell Sorting Made Fast and Easy with the Pala System</h3> <article class="product-data-wrapper "> The Pala Cell Sorter and Single Cell Dispenser is your go-to benchtop device for gentle, fluorescence activated single cell isolation or enrichment. Compatible with a wide range of cell types, you can dispense single cells into 96- or 384-well plates or perform target cell enrichment in tubes in as little as 7 minutes! </article> <div id="pp-orderblock-buttons"><div class="float-right mt-3"> <a class="btn a___button-primary m-1 mt-3 col-xs-4" href="/p/instruments/cell-sorting-single-cell-dispensing/request-quote?productName=Pala%20Cell%20Sorter%20and%20Single%20Cell%20Dispenser&catalogNumber=NI006&Instrument_Product_Category__c=Demo" target="_self"> Request Demo </a> <a class="btn a___button-primary m-1 mt-3 col-xs-4" href="/p/instruments/cell-sorting-single-cell-dispensing/request-quote?productName=Pala%20Cell%20Sorter%20and%20Single%20Cell%20Dispenser&catalogNumber=NI006&Instrument_Product_Category__c=Quote" target="_self"> Request Pricing </a> </div> </div> </div> <div class="col-xl-3" id="product_ads_wrapper"><article class="product-data-wrapper"> </article> </div> </div> </div> <div><div id="instrument_meet_section"><div id="instrument_meet_section" class="top_region"> <div class="row"> <div class="col-md-6"> <h3 class="mb-2">Meet Pala: The Benchtop Cell Sorter for Any Lab</h3> By combining proprietary microfluidics, flow cytometry, and liquid dispensing technologies, this benchtop cell sorter automates and simplifies single cell isolation across various applications – cell line development, cell engineering, single cell genomics, monoclonal antibody development, and rare cell isolation such as circulating tumor cells (CTCs) and circulating fetal cells (CFCs). The Pala Cell Sorter and Single Cell Dispenser is affordable, easy-to-use, low maintenance, and requires minimal training to operate! </div> <div class="col-md-6" > <div class="embed-responsive embed-responsive-16by9"> <iframe width="560" height="315" src="https://www.youtube.com/embed/xU0MAfe4clg" allow="accelerometer; encrypted-media; gyroscope; picture-in-picture" allowfullscreen> </iframe> </div> </div> </div> </div> </div> </div> <div><div id="instrument_additional_section"> <div class="paragraph paragraph--type--product-page-content paragraph--view-mode--full"> <div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <h2>Resources Featuring the Pala Cell Sorter</h2> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/literature/cell-line-development-for-biopharmaceutical-production-using-namocell-single-cell-dispenser" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/products/dr-lina-chakrabarti-headshot-525x300.png" alt="Dr Chakrabarti headshot" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/literature/cell-line-development-for-biopharmaceutical-production-using-namocell-single-cell-dispenser" > <h3 class="card_title_htag"></h3> </a> <div class="card_description flex-grow-1"> <div><p>From Your Peers with Dr. Lina Chakrabarti: Improved predictability and robustness of cell line development workflows</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/literature/cell-line-development-for-biopharmaceutical-production-using-namocell-single-cell-dispenser" > Download Whitepaper </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/literature/crispr-edited-cell-lines-using-namocell-single-cell-dispensers" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/products/dr-oscar-perez-leal-headshot-525x300.png" alt="Dr Perez-Leal Headshot" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/literature/crispr-edited-cell-lines-using-namocell-single-cell-dispensers" > <h3 class="card_title_htag"></h3> </a> <div class="card_description flex-grow-1"> <div><p>From Your Peers with Dr. Oscar Perez-Leal: Accelerate drug discovery with enhanced cell engineering</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/literature/crispr-edited-cell-lines-using-namocell-single-cell-dispensers" > Download Whitepaper </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/webinars/producing-high-quality-crispr-cas9-edited-hipscs-for-cardiac-disease-modeling" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/products/dr-maks-prondzynski-headshot-525x300.png" alt="Dr Prondzynski Headshot" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/webinars/producing-high-quality-crispr-cas9-edited-hipscs-for-cardiac-disease-modeling" > <h3 class="card_title_htag"></h3> </a> <div class="card_description flex-grow-1"> <div><p>Explore the cutting-edge advancements in CRISPR and hiPSCs</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/webinars/producing-high-quality-crispr-cas9-edited-hipscs-for-cardiac-disease-modeling" > Watch the Webinar featuring Dr. Maks Prondzynski On Demand </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="tab-content"><div id="about-data-tab-tab"></div> <ul class="nav nav-tabs nav-fill " id="productTab" role="tablist"> <li class="nav-item"> <a class="nav-link active" id="about-pala-cell-sorter-and-single-cell-dispenser-tab-tab" href="#about-pala-cell-sorter-and-single-cell-dispenser-tab" data-toggle="tab" role="tab" aria-controls="region-4171591922717" aria-selected="true" >About Pala Cell Sorter and Single Cell Dispenser</a> </li> <li class="nav-item"> <a class="nav-link" id="citations-tab-tab" href="#citations-tab" data-toggle="tab" role="tab" aria-controls="region-8961620056042" aria-selected="false" >Citations / Testimonials (2)</a> </li> </ul> <div class="tab-content rounded-bottom border-left border-right border-bottom mb-3" id="ProductTabContent"><div class="tab-pane fade show active mx-4" id="about-pala-cell-sorter-and-single-cell-dispenser-tab" data-tab-label="About Pala Cell Sorter and Single Cell Dispenser" role="tabpanel" aria-labelledby="about-pala-cell-sorter-and-single-cell-dispenser-tab-tab"><div class="product_details_anchors"><div class="product-pages-anchors nav mx-0 pt-4 pb-2 m___nav-anchors d-none d-lg-flex"><li id="how-can-pala-cell-sorter-and-single-cell-dispenser-help-you_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 jump-anchor active" href="#how-can-pala-cell-sorter-and-single-cell-dispenser-help-you" id="how-can-pala-cell-sorter-and-single-cell-dispenser-help-you_li" >How Can Pala Cell Sorter and Single Cell Dispenser Help You?</a> </li> <li id="how-does-pala-cell-sorter-and-single-cell-dispenser-work_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 jump-anchor" href="#how-does-pala-cell-sorter-and-single-cell-dispenser-work" id="how-does-pala-cell-sorter-and-single-cell-dispenser-work_li" >How Does Pala Cell Sorter and Single Cell Dispenser Work?</a> </li> <li id="applications_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 jump-anchor" href="#applications" id="applications_li" >Applications</a> </li> <li id="products-compatible-with-pala-cell-sorter-and-single-cell-dispenser_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 jump-anchor" href="#products-compatible-with-pala-cell-sorter-and-single-cell-dispenser" id="products-compatible-with-pala-cell-sorter-and-single-cell-dispenser_li" >Products Compatible with Pala Cell Sorter and Single Cell Dispenser</a> </li> <li id="specifications_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 jump-anchor" href="#specifications" id="specifications_li" >Specifications</a> </li> <li id="product-documents_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 product-documents" href="#product-documents" id="product-documents_li" >Product Documents</a> </li> </div> <div id="how-can-pala-cell-sorter-and-single-cell-dispenser-help-you" class="nav-link px-0" data-anchor-label="How Can Pala Cell Sorter and Single Cell Dispenser Help You?"><table class="product-data-wrapper tablesaw tablesaw-stack table" id="data_image_table_wrapper"><h3>How Can Pala Cell Sorter and Single Cell Dispenser Help You?</h3><article class="product-data-wrapper"> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-1052024124953.png" data-srcset="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-1052024124953.png" alt="Fast Single Cell Dispensing" title="How does the Pala set up time compare to FACS?" data-caption="The Pala significantly reduces set up and maintenance time compared to conventional FACS. Pala can be set up and run, achieving single cell isolation in as little as 7 minutes. Conventional FACS systems, can take over an hour to set up and provide results." data-badges="" data-application="N/A" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <p> <strong>How does the Pala set up time compare to FACS?</strong> The Pala significantly reduces set up and maintenance time compared to conventional FACS. Pala can be set up and run, achieving single cell isolation in as little as 7 minutes. Conventional FACS systems, can take over an hour to set up and provide results. </p> </td> </tr> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-1052024125215.png" data-srcset="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-1052024125215.png" alt="Gentle cell handling induces less stress response changes" title="How does the Pala Cell Sorter and Single Cell Dispenser compare to traditional FACS and limited dilution with sensitive cell lines?" data-caption="The Pala system is gentle and uses very low pressure (<2 psi) for cell sorting. In contrast, conventional FACS instruments use relatively high pressures (30-70 psi), which can be damaging for sensitive cells, resulting in reduced cell viability. The figure on the left shows a comparison of cellular stress response genes between cells isolated using a FACS instrument vs. using Bio-Techne's gentle cell sorting technology. Cells sorted with a FACS instrument showed induction of cellular stress response genes such as Ubiquitin C (Ubc), while cells sorted using Bio-Techne's technology show much lower expression of stress response genes. Limited dilution, on the other hand, is a gentle technique but does not yield high rates of single cell clones and has no fluorescence sorting capabilities resulting in laborious screening and high experimental failure rates." data-badges="" data-application="N/A" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <p> <strong>How does the Pala Cell Sorter and Single Cell Dispenser compare to traditional FACS and limited dilution with sensitive cell lines?</strong> The Pala system is gentle and uses very low pressure (<2 psi) for cell sorting. In contrast, conventional FACS instruments use relatively high pressures (30-70 psi), which can be damaging for sensitive cells, resulting in reduced cell viability. The figure on the left shows a comparison of cellular stress response genes between cells isolated using a FACS instrument vs. using Bio-Techne's gentle cell sorting technology. Cells sorted with a FACS instrument showed induction of cellular stress response genes such as Ubiquitin C (Ubc), while cells sorted using Bio-Techne's technology show much lower expression of stress response genes. Limited dilution, on the other hand, is a gentle technique but does not yield high rates of single cell clones and has no fluorescence sorting capabilities resulting in laborious screening and high experimental failure rates. </p> </td> </tr> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-1052024125634.jpg" data-srcset="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-1052024125634.jpg" alt="Pala is portable and can fit in a tissue culture hood" title="Can Pala fit in a tissue culture hood to keep my samples sterile?" data-caption="Pala is a compact, benchtop system ideal for fitting into a tissue culture hood for sterile sorting. You can carry out all the preparatory work on your cells and isolate them at the same workstation! At 35 lbs., Pala can be moved outside of the hood when not in use to free up valuable space. " data-badges="" data-application="N/A" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <p> <strong>Can Pala fit in a tissue culture hood to keep my samples sterile?</strong> Pala is a compact, benchtop system ideal for fitting into a tissue culture hood for sterile sorting. You can carry out all the preparatory work on your cells and isolate them at the same workstation! At 35 lbs., Pala can be moved outside of the hood when not in use to free up valuable space. </p> </td> </tr> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-1052024125818.jpg" data-srcset="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-1052024125818.jpg" alt="Sterile microfluidic cartridges reduce risk of contamination" title="I run multiple samples and sterile isolation is important in my work, how does the Pala cell sorter mitigate contamination risk?" data-caption="Pala utilizes disposable microfluidic cell cartridges, which are specifically designed for sterile isolation. The closed cartridge design, and the ease of switching between cartridges with different samples, eliminates the potential for sample to sample carryover." data-badges="" data-application="N/A" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <p> <strong>I run multiple samples and sterile isolation is important in my work, how does the Pala cell sorter mitigate contamination risk?</strong> Pala utilizes disposable microfluidic cell cartridges, which are specifically designed for sterile isolation. The closed cartridge design, and the ease of switching between cartridges with different samples, eliminates the potential for sample to sample carryover. </p> </td> </tr> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-105202413010.jpg" data-srcset="https://resources.rndsystems.com/images/datasheets/ni006_pala-single-cell-dispenser-488-561-with-laptop-105202413010.jpg" alt="Pala is simple and requires no specialized training" title="Pala is an innovative, easy-to-use system, supported by world class customer support." data-caption="The Pala system is automated and easy-to-use with an intuitive software interface. There is no extensive training or specialized expertise required. If you’re not sure, call tech support and we’ll be happy to help!" data-badges="" data-application="N/A" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <p> <strong>Pala is an innovative, easy-to-use system, supported by world class customer support.</strong> The Pala system is automated and easy-to-use with an intuitive software interface. There is no extensive training or specialized expertise required. If you’re not sure, call tech support and we’ll be happy to help! </p> </td> </tr> </article> </table> </div> <div id="how_does_work-anchor" class="nav-link static-anchor p-0" data-anchor-label="How Does Pala Cell Sorter and Single Cell Dispenser Work?"></div> <div id="applications-anchor" class="nav-link static-anchor p-0" data-anchor-label="Applications"></div> <div id="products_compatible-anchor" class="nav-link static-anchor p-0" data-anchor-label="Products Compatible with Pala Cell Sorter and Single Cell Dispenser"></div> <div id="specifications-anchor" class="nav-link static-anchor p-0" data-anchor-label="Specifications"></div> <div id="product-datasheet-anchor" class="nav-link static-anchor p-0" data-anchor-label="Product Documents"></div> </div> </div> <div class="tab-pane fade mx-4 py-4" id="citations-tab" data-tab-label="Citations / Testimonials (2)" role="tabpanel" aria-labelledby="citations-tab-tab"><div class="product_details_anchors mb-2"> <div class="nav mx-0 pt-4 pb-2 m___nav-anchors d-none d-lg-flex"> <li class="nav-item m-0"> <a class="nav-link jump-anchor active" href="#citations"> Citations </a> </li> <li class="nav-item m-0"> <a class="nav-link jump-anchor active" href="#testimonials"> Testimonials </a> </li> </div> </div> <div id="citations"> <div class="pp_filter_list border-bottom mb-4 pb-3"> <h2>Citations for Pala Cell Sorter and Single Cell Dispenser</h2> <p><a href="/resources/instrument-citations?instrument-platform=cell%20sorting%20and%20single%20cell%20dispensing" rel="nofollow noopener noreferrer" target="_blank">View all citations for the Cell Sorting and Single Cell Dispensing platform.</a><br> Please visit our Instrument Citation Database to search our collection of scientific articles that feature our instruments. </p> </div> </div> <div class="testimonials" id="testimonials"><article class="product-data-wrapper"> <div class="pp_filter_list mt-4 pt-4 border-bottom mb-4 pb-3"> <h2>Testimonials from your Peers for Cell Sorting and Single Cell Dispensing</h2> <div class="testimonials_showing pp_filters_showing row col-md-12 mb-2"> <span class="less">Showing  <span class="testimonials_show_min font-weight-bold">1</span> <span class="font-weight-bold">-</span> <span class="testimonials_show_max font-weight-bold">2</span> of <span class="testimonials_count font-weight-bold">2</span> testimonials </span> <span class="more font-weight-bold">Showing All</span> </div> <article role="article" class="contextual-region"> <div class="testimonial py-4"> <div class="row"> <aside class="col-lg-2 m___testimonial-aside-search text-center"> <article class="contextual-region"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/headshots/dr-perez-headshot.png" alt="Dr. Oscar Perez-Leal Headshot" loading="lazy"> </article> </aside> <section class="col-lg-10"> <div class="testimonial__quote"> <p>"Utilizing this machine (the Bio-Techne Single Cell Dispenser) has proven instrumental in streamlining the development process of single-cell clones for the cell lines I am working on. It has greatly facilitated the generation of valuable research tools, contributing to the overall progress and efficiency of my work."</p> </div> <div class="testimonial-link"> <a href="/resources/testimonials/from-your-peers-development-of-crispr-edited-cell-line-models-with-single-cell-dispenser">Accelerate the Development of CRISPR-Edited Cell Line Models Using Bio-Techne Single Cell Dispensers</a> </div> <p class="testimonial__profile mt-3"> <span class="font-weight-bold"> Dr. Oscar Perez-Leal, MD, </span> Assistant Professor, Temple University, School of Pharmacy </p> </section> </div> </div> </article> <article role="article" class="contextual-region"> <div class="testimonial py-4"> <div class="row"> <aside class="col-lg-2 m___testimonial-aside-search text-center"> <article class="contextual-region"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/lina-chakrabarti-headshot-480x480.png" alt="Dr. Lina Chakrabarti from AstraZeneca discusses how the single cell sorting dispensing technology on the Pala™ system boosted cell line development workflows for biopharmaceutical manufacturing." loading="lazy"> </article> </aside> <section class="col-lg-10"> <div class="testimonial__quote"> <p>"The introduction of the Pala Single Cell Dispenser has brought significant reduction in sorting time and cost of goods. The device is small, quick to set up and easy-to-use with high probability of monoclonality and clonal outgrowth."</p> </div> <div class="testimonial-link"> <a href="/resources/testimonials/fyp-cell-line-development-biopharmaceutical-production-with-single-cell-dispenser">Cell Line Development for Biopharmaceutical Production</a> </div> <p class="testimonial__profile mt-3"> <span class="font-weight-bold"> Lina Chakrabarti, PhD, </span> Associate Director R&D, AstraZeneca </p> </section> </div> </div> </article> <span id="more-testimonials" style="display:none"> </span> <div id="testimonial_counts" data-max="2" data-min="5"> <div class="testimonials_showing pp_filters_showing row col-md-12 mb-2"> <span class="less">Showing  <span class="testimonials_show_min font-weight-bold">1</span> <span class="font-weight-bold">-</span> <span class="testimonials_show_max font-weight-bold">2</span> of <span class="testimonials_count font-weight-bold">2</span> testimonials </span> <span class="more font-weight-bold">Showing All</span> </div> </div> <div class="text-center"> </div> </div> </article> </div> </div> </div> </div> <div><div id="accordion" class="border mb-4"> <div class="rounded-top bg-white"> <h3 class="m-0 p-3">More Information About Pala Cell Sorter and Single Cell Dispenser</h3> </div> <div class="vtab-section" data-section="How Does Pala Cell Sorter and Single Cell Dispenser Work?" id="how-does-pala-cell-sorter-and-single-cell-dispenser-work"> <div class="card-header rounded-top"> <a id="how-does-pala-cell-sorter-and-single-cell-dispenser-work-link" class="collapsed" data-toggle="collapse" data-target="#collapse_region-5781592502255" aria-expanded="false" aria-controls="collapse_region-5781592502255"> <h5 class="mb-0"> How Does Pala Cell Sorter and Single Cell Dispenser Work? </h5> </a> </div> <div id="collapse_region-5781592502255" class="collapse " aria-labelledby="heading_region-5781592502255" data-parent="#accordion"> <div class="card-body"> <div id="how-does-pala-cell-sorter-and-single-cell-dispenser-work-vtab" data-tab-label="How Does Pala Cell Sorter and Single Cell Dispenser Work?" role="tabpanel" aria-labelledby="how-does-pala-cell-sorter-and-single-cell-dispenser-work-vtab-tab"><div id="instrument_how_work_content"> <div class="paragraph paragraph--type--product-page-content paragraph--view-mode--full"> <div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p>The Pala Single Cell Dispenser sorts directly into your 96- or 384-well plates, all under 7 minutes! This benchtop single cell sorter automates and simplifies single cell isolation by combining proprietary microfluidics, flow cytometry, and liquid dispensing technologies. The Pala Single Cell Dispenser is affordable, easy-to-use, zero maintenance, and requires no special training to operate!<br> <br> Pala is suitable for use across various applications including <a href="/resources/instrument-applications/cell-line-development-single-cell-dispenser">cell line development</a>, <a href="/resources/instrument-applications/crispr-cell-engineering-single-cell-dispenser">cell engineering</a>, <a href="/resources/instrument-applications/single-cell-genomics-single-cell-dispenser">single cell genomics</a>, <a href="/resources/instrument-applications/antibody-discovery-single-cell-dispenser">monoclonal antibody development</a>, and <a href="/resources/instrument-applications/rare-cell-isolation-single-cell-dispenser">rare cell isolation</a> such as circulating tumor cells (CTCs) and circulating fetal cells (CFCs).</p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="vtab-section" data-section="Applications" id="applications"> <div class="card-header rounded-top"> <a id="applications-link" class="collapsed" data-toggle="collapse" data-target="#collapse_region-4951592502294" aria-expanded="false" aria-controls="collapse_region-4951592502294"> <h5 class="mb-0"> Applications </h5> </a> </div> <div id="collapse_region-4951592502294" class="collapse " aria-labelledby="heading_region-4951592502294" data-parent="#accordion"> <div class="card-body"> <div id="applications-vtab" data-tab-label="Applications" role="tabpanel" aria-labelledby="applications-vtab-tab"><div id="applications_wrapper"> <div class="paragraph paragraph--type--product-page-content paragraph--view-mode--full"> <div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <h2>Single Cell Dispenser Applications</h2> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/instrument-applications/single-cell-genomics-single-cell-dispenser" > <div class="teaser-card-image-crop mb-3"> <img loading="lazy" class="card-background-image card-img-top" src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/dark-purple-teaser-background.png" /> </div> <div class="card-foreground-image"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/exosomes-3d-525x300-v1.png" alt="Exosomes" loading="lazy" > </div> </a> <a class="card_title_link" href="/resources/instrument-applications/single-cell-genomics-single-cell-dispenser" > <h3 class="card_title_htag"></h3> </a> <div class="card_description flex-grow-1"> </div> <div class="card-bottom-link"> <div> <a href="/resources/instrument-applications/single-cell-genomics-single-cell-dispenser" > Single Cell Genomics </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/instrument-applications/cell-line-development-single-cell-dispenser" > <div class="teaser-card-image-crop mb-3"> <img loading="lazy" class="card-background-image card-img-top" src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/dark-purple-teaser-background.png" /> </div> <div class="card-foreground-image"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/cdx-quantidex-cancer-cell-350x350.png" alt="general cancer cell b" loading="lazy" > </div> </a> <a class="card_title_link" href="/resources/instrument-applications/cell-line-development-single-cell-dispenser" > <h3 class="card_title_htag"></h3> </a> <div class="card_description flex-grow-1"> </div> <div class="card-bottom-link"> <div> <a href="/resources/instrument-applications/cell-line-development-single-cell-dispenser" > Cell Line Development </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/instrument-applications/crispr-cell-engineering-single-cell-dispenser" > <div class="teaser-card-image-crop mb-3"> <img loading="lazy" class="card-background-image card-img-top" src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/dark-purple-teaser-background.png" /> </div> <div class="card-foreground-image"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/banners/crispr-hero-foreground-480x480.png" alt="CRISPR Gene Editing" loading="lazy" > </div> </a> <a class="card_title_link" href="/resources/instrument-applications/crispr-cell-engineering-single-cell-dispenser" > <h3 class="card_title_htag"></h3> </a> <div class="card_description flex-grow-1"> </div> <div class="card-bottom-link"> <div> <a href="/resources/instrument-applications/crispr-cell-engineering-single-cell-dispenser" > CRISPR & Cell Engineering </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/instrument-applications/antibody-discovery-single-cell-dispenser" > <div class="teaser-card-image-crop mb-3"> <img loading="lazy" class="card-background-image card-img-top" src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/dark-purple-teaser-background.png" /> </div> <div class="card-foreground-image"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/bt-antibodies-hero.png" alt="Antibody Hero Cell" loading="lazy" > </div> </a> <a class="card_title_link" href="/resources/instrument-applications/antibody-discovery-single-cell-dispenser" > <h3 class="card_title_htag"></h3> </a> <div class="card_description flex-grow-1"> </div> <div class="card-bottom-link"> <div> <a href="/resources/instrument-applications/antibody-discovery-single-cell-dispenser" > Antibody Discovery </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/instrument-applications/rare-cell-isolation-single-cell-dispenser" > <div class="teaser-card-image-crop mb-3"> <img loading="lazy" class="card-background-image card-img-top" src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/dark-purple-teaser-background.png" /> </div> <div class="card-foreground-image"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/therapeutic-manufacturing/v3_io-clinical-lp_gene-edited-cell.png" alt="Gene Edited Cell" loading="lazy" > </div> </a> <a class="card_title_link" href="/resources/instrument-applications/rare-cell-isolation-single-cell-dispenser" > <h3 class="card_title_htag"></h3> </a> <div class="card_description flex-grow-1"> </div> <div class="card-bottom-link"> <div> <a href="/resources/instrument-applications/rare-cell-isolation-single-cell-dispenser" > Rare Cell Isolation </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="vtab-section" data-section="Products Compatible with Pala Cell Sorter and Single Cell Dispenser" id="products-compatible-with-pala-cell-sorter-and-single-cell-dispenser"> <div class="card-header rounded-top"> <a id="products-compatible-with-pala-cell-sorter-and-single-cell-dispenser-link" class="collapsed" data-toggle="collapse" data-target="#collapse_region-7641628092667" aria-expanded="false" aria-controls="collapse_region-7641628092667"> <h5 class="mb-0"> Products Compatible with Pala Cell Sorter and Single Cell Dispenser </h5> </a> </div> <div id="collapse_region-7641628092667" class="collapse " aria-labelledby="heading_region-7641628092667" data-parent="#accordion"> <div class="card-body"> <div id="products-compatible-with-pala-cell-sorter-and-single-cell-dispenser-vtab" data-tab-label="Products Compatible with Pala Cell Sorter and Single Cell Dispenser" role="tabpanel" aria-labelledby="products-compatible-with-pala-cell-sorter-and-single-cell-dispenser-vtab-tab"><div id="products_compatible_with_instrument"><article class="product-data-wrapper"> <ul class="compatible_instruments list-unstyled m-0"> <li class="py-2"><a href="/search?keywords=Cell%20Sorting%20and%20Single%20Cell%20Dispensing%20Consumables&sub_category=Cell%20Sorting%20and%20Single%20Cell%20Dispensing%20Consumables&compatible_instrument=Pala&view=condensed">Cell Sorting and Single Cell Dispensing Consumables</a></li> <li class="py-2"><a href="/search?keywords=cell%20sorting%20and%20single%20cell%20dispensing&compatible_instrument=Pala&view=condensed">View All Products Compatible with Pala</a></li> </ul> </article> </div> </div> </div> </div> </div> <div class="vtab-section" data-section="Specifications" id="specifications"> <div class="card-header rounded-top"> <a id="specifications-link" class="collapsed" data-toggle="collapse" data-target="#collapse_region-9701592502350" aria-expanded="false" aria-controls="collapse_region-9701592502350"> <h5 class="mb-0"> Specifications </h5> </a> </div> <div id="collapse_region-9701592502350" class="collapse " aria-labelledby="heading_region-9701592502350" data-parent="#accordion"> <div class="card-body"> <div id="specifications-vtab" data-tab-label="Specifications" role="tabpanel" aria-labelledby="specifications-vtab-tab"><div id="instrument_specifications"><table class="tablesaw tablesaw-stack app_table my-3 table-bordered" data-tablesaw-mode="stack"> <thead class="ds_table_head bg-light-gray"> <th class="ds_table_head_cell w-25 p-3">Description</th> <th class="ds_table_head_cell w-25 p-3">Single Cell Dispensing</th> <th class="ds_table_head_cell w-25 p-3">Bulk Sorting</th> </thead> <tbody class="bg-white"> <tr class="ds_table_row"> <td>Excitation Laser Combos</td> <td colspan="2" class="text-center"> 405/488 or 488/561 </td> </tr> <tr class="ds_table_row"> <td>Light Scatter</td> <td colspan="2" class="text-center"> Forward & Total </td> </tr> <tr class="ds_table_row"> <td>Fluorescence Channels</td> <td colspan="2" class="text-center"> 11 (405/488) or 9 (488/561) </td> </tr> <tr class="ds_table_row"> <td>Laser Modes</td> <td colspan="2" class="text-center"> Single or Dual </td> </tr> <tr class="ds_table_row"> <td>Input Sample Volume</td> <td colspan="2" class="text-center"> 100-600 uL </td> </tr> <tr class="ds_table_row"> <td>Input Sample Density</td> <td colspan="2" class="text-center"> 100 cells - 150M cells/mL </td> </tr> <tr class="ds_table_row"> <td>Dispensing Volume</td> <td colspan="1" class="text-left"> 1 uL/cell </td> <td colspan="1" class="text-left"> As low as 25 nL/cell </td> </tr> <tr class="ds_table_row"> <td>Dispensing Format</td> <td colspan="1" class="text-left"> 96 or 384 well plates </td> <td colspan="1" class="text-left"> Microcentrifuge tube </td> </tr> <tr class="ds_table_row"> <td>Dispense Speed</td> <td colspan="1" class="text-left"> < 2 min/96 well plate </td> <td colspan="1" class="text-left"> Up to 50 events/sec </td> </tr> <tr class="ds_table_row"> <td>Rare Cell Enrichment</td> <td colspan="2" class="text-center"> Enabled </td> </tr> <tr class="ds_table_row"> <td>Sorting Pressure</td> <td colspan="2" class="text-center"> <2 PSI </td> </tr> <tr class="ds_table_row"> <td>Initialization Time</td> <td colspan="2" class="text-center"> 5 min </td> </tr> <tr class="ds_table_row"> <td>Sterility</td> <td colspan="2" class="text-center"> Enabled </td> </tr> <tr class="ds_table_row"> <td>Dimensions</td> <td colspan="2" class="text-center"> 25 x 14 x 9 in <br /> 64 x 36 x 23 cm <br /> (Fits in a Standard Biosafety Cabinet) </td> </tr> <tr class="ds_table_row"> <td>Weight</td> <td colspan="2" class="text-center"> 35 lbs <br /> 16 kg </td> </tr> </tbody> </table> </div> </div> </div> </div> </div> </div> </div> <div id="product-documents"> </div> <div id="product-page-details" data-time-Total="0" data-time-ToCompile="0" data-time-ToBuild="0" data-time-Datapoints="0" data-time-Template="0" data-time-Post-EPCC="0" data-time-EPCC="0" data-renderTime="Wednesday 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Pala Cell Sorter and Single Cell Dispenser (NI006) by Bio-Techne