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Globularni protein – Wikipedija/Википедија

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<div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Sadržaj</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">sakrij</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Početak</div> </a> </li> <li id="toc-Globularne_strukture_i_rastvorljivost" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Globularne_strukture_i_rastvorljivost"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Globularne strukture i rastvorljivost</span> </div> </a> <ul id="toc-Globularne_strukture_i_rastvorljivost-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reference" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Reference"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Reference</span> </div> </a> <ul id="toc-Reference-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Spoljašnje_veze" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Spoljašnje_veze"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Spoljašnje veze</span> </div> </a> <ul id="toc-Spoljašnje_veze-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Sadržaj" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Prikaži/sakrij sadržaj" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Prikaži/sakrij sadržaj</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading" lang="sh-Latn" dir="ltr"><span class="mw-page-title-main">Globularni protein</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" lang="sh-Latn" dir="ltr"> <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Prijedi na druge jezične varijante članka. Dostupno je na 31 jeziku" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-31" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">31 jezik</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A8%D8%B1%D9%88%D8%AA%D9%8A%D9%86_%D9%83%D8%B1%D9%88%D9%8A" title="بروتين كروي — Arapski" lang="ar" hreflang="ar" data-title="بروتين كروي" data-language-autonym="العربية" data-language-local-name="Arapski" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-be mw-list-item"><a href="https://be.wikipedia.org/wiki/%D0%93%D0%BB%D0%B0%D0%B1%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D1%8B%D1%8F_%D0%B1%D1%8F%D0%BB%D0%BA%D1%96" title="Глабулярныя бялкі — Beloruski" lang="be" hreflang="be" data-title="Глабулярныя бялкі" data-language-autonym="Беларуская" data-language-local-name="Beloruski" class="interlanguage-link-target"><span>Беларуская</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%93%D0%BB%D0%BE%D0%B1%D1%83%D0%BB%D0%B0%D1%80%D0%B5%D0%BD_%D0%B1%D0%B5%D0%BB%D1%82%D1%8A%D0%BA" title="Глобуларен белтък — Bugarski" lang="bg" hreflang="bg" data-title="Глобуларен белтък" data-language-autonym="Български" data-language-local-name="Bugarski" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Globulasti_proteini" title="Globulasti proteini — Bosanski" lang="bs" hreflang="bs" data-title="Globulasti proteini" data-language-autonym="Bosanski" data-language-local-name="Bosanski" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Prote%C3%AFna_globular" title="Proteïna globular — Katalonski" lang="ca" hreflang="ca" data-title="Proteïna globular" data-language-autonym="Català" data-language-local-name="Katalonski" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Globul%C3%A1rn%C3%AD_protein" title="Globulární protein — Češki" lang="cs" hreflang="cs" data-title="Globulární protein" data-language-autonym="Čeština" data-language-local-name="Češki" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Globul%C3%A4re_Proteine" title="Globuläre Proteine — Nemački" lang="de" hreflang="de" data-title="Globuläre Proteine" data-language-autonym="Deutsch" data-language-local-name="Nemački" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Globular_protein" title="Globular protein — Engleski" lang="en" hreflang="en" data-title="Globular protein" data-language-autonym="English" data-language-local-name="Engleski" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Prote%C3%ADna_globular" title="Proteína globular — Španski" lang="es" hreflang="es" data-title="Proteína globular" data-language-autonym="Español" data-language-local-name="Španski" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Proteina_globular" title="Proteina globular — Baskijski" lang="eu" hreflang="eu" data-title="Proteina globular" data-language-autonym="Euskara" data-language-local-name="Baskijski" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%BE%D8%B1%D9%88%D8%AA%D8%A6%DB%8C%D9%86%E2%80%8C%D9%87%D8%A7%DB%8C_%DA%A9%D8%B1%D9%88%DB%8C" title="پروتئین‌های کروی — Persijski" lang="fa" hreflang="fa" data-title="پروتئین‌های کروی" data-language-autonym="فارسی" data-language-local-name="Persijski" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Prot%C3%A9ine_globulaire" title="Protéine globulaire — Francuski" lang="fr" hreflang="fr" data-title="Protéine globulaire" data-language-autonym="Français" data-language-local-name="Francuski" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ga mw-list-item"><a href="https://ga.wikipedia.org/wiki/Pr%C3%B3it%C3%A9in_chruinneogach" title="Próitéin chruinneogach — Irski" lang="ga" hreflang="ga" data-title="Próitéin chruinneogach" data-language-autonym="Gaeilge" data-language-local-name="Irski" class="interlanguage-link-target"><span>Gaeilge</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Prote%C3%ADna_globular" title="Proteína globular — Galski" lang="gl" hreflang="gl" data-title="Proteína globular" data-language-autonym="Galego" data-language-local-name="Galski" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%97%E0%A5%8B%E0%A4%B2%E0%A4%BE%E0%A4%95%E0%A4%BE%E0%A4%B0_%E0%A4%AA%E0%A5%8D%E0%A4%B0%E0%A5%8B%E0%A4%9F%E0%A5%80%E0%A4%A8" title="गोलाकार प्रोटीन — Hindi" lang="hi" hreflang="hi" data-title="गोलाकार प्रोटीन" data-language-autonym="हिन्दी" data-language-local-name="Hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Kuglasta_bjelan%C4%8Devina" title="Kuglasta bjelančevina — Hrvatski" lang="hr" hreflang="hr" data-title="Kuglasta bjelančevina" data-language-autonym="Hrvatski" data-language-local-name="Hrvatski" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Protein_globular" title="Protein globular — Indonezijski" lang="id" hreflang="id" data-title="Protein globular" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonezijski" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Proteina_globulare" title="Proteina globulare — Italijanski" lang="it" hreflang="it" data-title="Proteina globulare" data-language-autonym="Italiano" data-language-local-name="Italijanski" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E7%90%83%E7%8A%B6%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA" title="球状タンパク質 — Japanski" lang="ja" hreflang="ja" data-title="球状タンパク質" data-language-autonym="日本語" data-language-local-name="Japanski" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%93%D0%BB%D0%BE%D0%B1%D1%83%D0%BB%D1%8F%D1%80%D0%BB%D1%8B_%D0%B1%D0%B5%D0%BB%D0%BE%D0%BA%D1%82%D0%B0%D1%80" title="Глобулярлы белоктар — Kozački" lang="kk" hreflang="kk" data-title="Глобулярлы белоктар" data-language-autonym="Қазақша" data-language-local-name="Kozački" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EA%B5%AC%EC%83%81_%EB%8B%A8%EB%B0%B1%EC%A7%88" title="구상 단백질 — Korejski" lang="ko" hreflang="ko" data-title="구상 단백질" data-language-autonym="한국어" data-language-local-name="Korejski" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%93%D0%BB%D0%BE%D0%B1%D1%83%D0%BB%D0%B0%D1%80%D0%BD%D0%B0_%D0%B1%D0%B5%D0%BB%D0%BA%D0%BE%D0%B2%D0%B8%D0%BD%D0%B0" title="Глобуларна белковина — Makedonski" lang="mk" hreflang="mk" data-title="Глобуларна белковина" data-language-autonym="Македонски" data-language-local-name="Makedonski" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Globulair_eiwit" title="Globulair eiwit — Holandski" lang="nl" hreflang="nl" data-title="Globulair eiwit" data-language-autonym="Nederlands" data-language-local-name="Holandski" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Globul%C3%A6re_proteiner" title="Globulære proteiner — Norveški bokmål" lang="nb" hreflang="nb" data-title="Globulære proteiner" data-language-autonym="Norsk bokmål" data-language-local-name="Norveški bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Prote%C3%ADna_globular" title="Proteína globular — Portugalski" lang="pt" hreflang="pt" data-title="Proteína globular" data-language-autonym="Português" data-language-local-name="Portugalski" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%93%D0%BB%D0%BE%D0%B1%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D1%8B%D0%B5_%D0%B1%D0%B5%D0%BB%D0%BA%D0%B8" title="Глобулярные белки — Ruski" lang="ru" hreflang="ru" data-title="Глобулярные белки" data-language-autonym="Русский" data-language-local-name="Ruski" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Globular_protein" title="Globular protein — Simple English" lang="en-simple" hreflang="en-simple" data-title="Globular protein" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Globularni_protein" title="Globularni protein — Srpski" lang="sr" hreflang="sr" data-title="Globularni protein" data-language-autonym="Српски / srpski" data-language-local-name="Srpski" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Globul%C3%A4ra_proteiner" title="Globulära proteiner — Švedski" lang="sv" hreflang="sv" data-title="Globulära proteiner" data-language-autonym="Svenska" data-language-local-name="Švedski" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%93%D0%BB%D0%BE%D0%B1%D1%83%D0%BB%D1%8F%D1%80%D0%BD%D1%96_%D0%B1%D1%96%D0%BB%D0%BA%D0%B8" title="Глобулярні білки — Ukrajinski" lang="uk" hreflang="uk" data-title="Глобулярні білки" data-language-autonym="Українська" data-language-local-name="Ukrajinski" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E7%90%83%E7%8A%B6%E8%9B%8B%E7%99%BD%E8%B4%A8" title="球状蛋白质 — Kineski" lang="zh" hreflang="zh" data-title="球状蛋白质" data-language-autonym="中文" data-language-local-name="Kineski" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q901969#sitelinks-wikipedia" title="Uredi međujezične poveznice" class="wbc-editpage">Uredi veze</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Imenski prostori"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" lang="sh-Latn" dir="ltr"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a 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src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3d/1GZX_Haemoglobin.png/300px-1GZX_Haemoglobin.png" decoding="async" width="300" height="300" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3d/1GZX_Haemoglobin.png/450px-1GZX_Haemoglobin.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/3d/1GZX_Haemoglobin.png/600px-1GZX_Haemoglobin.png 2x" data-file-width="1600" data-file-height="1600" /></a><figcaption>Trodimenziona struktura <a href="/wiki/Hemoglobin" title="Hemoglobin">hemoglobina</a></figcaption></figure> <p><b>Globularni proteini</b> (<i>sferoproteini</i>) su jedna od tri glavne klase proteina.<sup id="cite_ref-VoetBiochemistry3rd_1-0" class="reference"><a href="#cite_note-VoetBiochemistry3rd-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Ovi proteini imaju oblik <a href="/wiki/Sfera" title="Sfera">sfere</a> i uglavnom su rastvorni u vodenim rastvorima. Oni formiraju <a href="/wiki/Koloid" title="Koloid">koloidne</a> rastvore. Po toj karakteristici se razlikuju od <a href="/wiki/Fibrilarni_proteini" title="Fibrilarni proteini">fibrilarnih proteina</a>, koji su praktično nerastvorni. Konformacije proteina i njihova stabilnost uslovljavaju njegovu funkciju.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> </p><p>Termin <a href="/wiki/Globin" title="Globin">globin</a> se može specifičnije koristiti za označavanje proteina koji imaju <a href="/wiki/Globinski_sklop" title="Globinski sklop">globinski sklop</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Globularne_strukture_i_rastvorljivost">Globularne strukture i rastvorljivost</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Globularni_protein&amp;veaction=edit&amp;section=1" title="Uredi odjeljak Globularne strukture i rastvorljivost" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Globularni_protein&amp;action=edit&amp;section=1" title="Uredi kôd odjeljka Globularne strukture i rastvorljivost"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Sferičnu strukturu indukuje proteinska <a href="/wiki/Tercijarna_struktura_proteina" title="Tercijarna struktura proteina">tercijarna struktura</a>. Nepolarne (<a href="/wiki/Hidrofobnost" class="mw-redirect" title="Hidrofobnost">hidrofobne</a>) aminokiseline su locirane u unutrašnjosti molekula, dok su <a href="/wiki/Hemijska_polarnost" title="Hemijska polarnost">polarne</a> (hidrofilne) aminokiseline vezane u spoljašnjem sloju, što omogućava <a href="/wiki/Me%C4%91umolekulska_sila" title="Međumolekulska sila">dipol-dipol interakcije</a> sa <a href="/wiki/Rastvara%C4%8D" class="mw-redirect" title="Rastvarač">rastvaračem</a>, čime se objašnjava molekulska rastvorljivost. </p><p>Način na koji se proteini prirodno savijaju još uvek nije potpuno poznat. Deo problema proteinskog savijanja je da se mnoštvo nekovalentnih, slabih interakcija formira, kao što su <a href="/wiki/Vodoni%C4%8Dna_veza" title="Vodonična veza">vodonične veze</a> i <a href="/wiki/Van_der_Valsova_veza" class="mw-redirect" title="Van der Valsova veza">Van der Walsove interakcije</a>. Postoje dva moguća mehanizma za savijanje globularnih proteina, difuzioni-kolizioni model i nukleaciono kondenzacioni model. Nedavni nalazi su pokazali da se globularni proteini, poput PTP-BL PDZ2, savijaju koristeći karakteristike oba modela. Iz tih nalaza proizilazi da prelazna stanja proteina mogu da utiču na način savijanja. </p> <div class="mw-heading mw-heading2"><h2 id="Reference">Reference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Globularni_protein&amp;veaction=edit&amp;section=2" title="Uredi odjeljak Reference" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Globularni_protein&amp;action=edit&amp;section=2" title="Uredi kôd odjeljka Reference"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r41556849">.mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width reflist-columns-2"> <ol class="references"> <li id="cite_note-VoetBiochemistry3rd-1"><span class="mw-cite-backlink"><a href="#cite_ref-VoetBiochemistry3rd_1-0">↑</a></span> <span class="reference-text"><span class="citation book">Donald Voet, Judith G. Voet&#32;(2005).&#32;<a rel="nofollow" class="external text" href="http://www.chem.upenn.edu/chem/research/faculty.php?browse=V"><i>Biochemistry</i></a>&#32;(3 izd.).&#32;Wiley.&#32;<a href="/wiki/International_Standard_Book_Number" class="mw-redirect" title="International Standard Book Number">ISBN</a>&#160;<a href="/wiki/Posebno:Tra%C5%BEi_ISBN/978-0-471-19350-0" title="Posebno:Traži ISBN/978-0-471-19350-0">978-0-471-19350-0</a>.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Biochemistry&amp;rft.aulast=Donald+Voet%2C+Judith+G.+Voet&amp;rft.au=Donald+Voet%2C+Judith+G.+Voet&amp;rft.date=2005&amp;rft.edition=3&amp;rft.pub=Wiley&amp;rft.isbn=978-0-471-19350-0&amp;rft_id=http%3A%2F%2Fwww.chem.upenn.edu%2Fchem%2Fresearch%2Ffaculty.php%3Fbrowse%3DV&amp;rfr_id=info:sid/en.wikipedia.org:Globularni_protein"><span style="display: none;">&#160;</span></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text"><span class="citation Journal">Carlo Travaglini-Allocatelli, Ylva Ivarsson, Per Jemth and Stefano Gianni&#32;(2009).&#32;<a rel="nofollow" class="external text" href="http://www.sciencedirect.com/science/article/pii/S0959440X08001759">„Folding and stability of globular proteins and implications for function”</a>.&#32;<i>Current Opinion in Structural Biology</i>&#32;<b>19</b>: 3–7.</span><span class="Z3988" title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=article&amp;rft.atitle=Folding+and+stability+of+globular+proteins+and+implications+for+function&amp;rft.jtitle=Current+Opinion+in+Structural+Biology&amp;rft.aulast=Carlo+Travaglini-Allocatelli%2C+Ylva+Ivarsson%2C+Per+Jemth+and+Stefano+Gianni&amp;rft.au=Carlo+Travaglini-Allocatelli%2C+Ylva+Ivarsson%2C+Per+Jemth+and+Stefano+Gianni&amp;rft.date=2009&amp;rft.volume=19&amp;rft.pages=3%E2%80%937&amp;rft_id=http%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fpii%2FS0959440X08001759&amp;rfr_id=info:sid/en.wikipedia.org:Globularni_protein"><span style="display: none;">&#160;</span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Spoljašnje_veze"><span id="Spolja.C5.A1nje_veze"></span>Spoljašnje veze</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Globularni_protein&amp;veaction=edit&amp;section=3" title="Uredi odjeljak Spoljašnje veze" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Globularni_protein&amp;action=edit&amp;section=3" title="Uredi kôd odjeljka Spoljašnje veze"><span>uredi kod</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Medical_Subject_Headings" class="mw-redirect" title="Medical Subject Headings">MeSH</a> <i><a rel="nofollow" class="external text" href="//www.nlm.nih.gov/cgi/mesh/2009/MB_cgi?mode=&amp;term=Globins">Globins</a></i></li></ul> <div style="clear:both;"></div> <div class="navbox-styles nomobile"><style data-mw-deduplicate="TemplateStyles:r41348688">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output 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a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-prikaži"><a href="/wiki/%C5%A0ablon:Proteinske_teme-lat" title="Šablon:Proteinske teme-lat"><abbr title="Pogledajte šablon" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">p</abbr></a></li><li class="nv-razgovor"><a href="/wiki/Razgovor_o_%C5%A1ablonu:Proteinske_teme-lat" title="Razgovor o šablonu:Proteinske teme-lat"><abbr title="Razgovarajte o šablonu" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">r</abbr></a></li><li class="nv-uredi"><a class="external text" href="https://sh.wikipedia.org/w/index.php?title=%C5%A0ablon:Proteinske_teme-lat&amp;action=edit"><abbr title="Uredite šablon" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">u</abbr></a></li></ul></div><div id="Proteini" style="font-size:114%;margin:0 4em"><a href="/wiki/Protein" title="Protein">Proteini</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Procesi</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Proteinska_biosinteza" class="mw-redirect" title="Proteinska biosinteza">Proteinska biosinteza</a>&#160;<span style="font-weight:bold;">•</span> <a href="/wiki/Posttranslaciona_modifikacija" title="Posttranslaciona modifikacija">Posttranslaciona modifikacija</a>&#160;<span style="font-weight:bold;">•</span> <a href="/wiki/Proteinsko_sklapanje" class="mw-redirect" title="Proteinsko sklapanje">Proteinsko sklapanje</a>&#160;<span style="font-weight:bold;">•</span> <a href="/wiki/Proteinsko_sortiranje" title="Proteinsko sortiranje">Proteinsko sortiranje</a>&#160;<span style="font-weight:bold;">•</span> <a href="/wiki/Proteom" title="Proteom">Proteom</a>&#160;<span style="font-weight:bold;">•</span> <a href="/wiki/Proteinske_metode" title="Proteinske metode">Proteinske metode</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Strukture</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Proteinska_struktura" title="Proteinska struktura">Proteinska struktura</a>&#160;<span style="font-weight:bold;">•</span> <a href="/wiki/Proteinski_domen" title="Proteinski domen">Proteinski strukturni domeni</a>&#160;<span style="font-weight:bold;">•</span> <a href="/wiki/Proteazom" class="mw-redirect" title="Proteazom">Proteazom</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Tipovi</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Spisak_tipova_proteina" class="mw-redirect" title="Spisak tipova proteina">Spisak tipova proteina</a>&#160;<span style="font-weight:bold;">•</span> <a href="/wiki/Membranski_protein" title="Membranski protein">Membranski protein</a>&#160;<span style="font-weight:bold;">•</span> <a class="mw-selflink selflink">Globularni protein</a> (<a href="/wiki/Globulin" title="Globulin">Globulin</a>, <a href="/wiki/Albumin" title="Albumin">Albumin</a>)&#160;<span style="font-weight:bold;">•</span> <a href="/wiki/Skleroprotein" class="mw-redirect" title="Skleroprotein">Fibrozni protein</a></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite"><div><b><a href="/wiki/Biohemija" title="Biohemija">Biohemijske</a> <a href="/wiki/%C5%A0ablon:Metabolizam-lat" title="Šablon:Metabolizam-lat">familije</a>:</b> <a href="/wiki/%C5%A0ablon:Ugljeni_hidrati-lat" class="mw-redirect" title="Šablon:Ugljeni hidrati-lat">Ugljeni hidrati</a> (<a href="/w/index.php?title=%C5%A0ablon:Glikozidi-lat&amp;action=edit&amp;redlink=1" class="new" title="Šablon:Glikozidi-lat (stranica ne postoji)">Glikozidi</a>,<a href="/wiki/%C5%A0ablon:Alkoholi-lat" title="Šablon:Alkoholi-lat">Alkoholi</a>)&#160;&#8226;&#32; <a href="/wiki/%C5%A0ablon:Lipidi-lat" title="Šablon:Lipidi-lat">Lipidi</a> (<a href="/w/index.php?title=%C5%A0ablon:Holesterol_i_steroidni_intermedijari-lat&amp;action=edit&amp;redlink=1" class="new" title="Šablon:Holesterol i steroidni intermedijari-lat (stranica ne postoji)">Steroidi</a>,<a href="/wiki/%C5%A0ablon:Fosfolipidi-lat" title="Šablon:Fosfolipidi-lat">Fosfolipidi</a>,<a href="/wiki/%C5%A0ablon:Sfingolipidi-lat" title="Šablon:Sfingolipidi-lat">Glikolipidi</a>,<a href="/wiki/%C5%A0ablon:Masne_kiseline-lat" title="Šablon:Masne kiseline-lat">Masne kiseline</a>,<a href="/w/index.php?title=%C5%A0ablon:Tetrapiroli-lat&amp;action=edit&amp;redlink=1" class="new" title="Šablon:Tetrapiroli-lat (stranica ne postoji)">Tetrapiroli</a>)&#160;&#8226;&#32; <a href="/wiki/%C5%A0ablon:Proteinske_teme-lat" title="Šablon:Proteinske teme-lat">Proteini</a> (<a href="/wiki/%C5%A0ablon:Aminokiseline-lat" title="Šablon:Aminokiseline-lat">Aminokiseline</a>,<a href="/wiki/%C5%A0ablon:Peptidi-lat" class="mw-redirect" title="Šablon:Peptidi-lat">Peptidi</a>,<a href="/wiki/%C5%A0ablon:Glikoproteini-lat" title="Šablon:Glikoproteini-lat">Glikoproteini</a>)&#160;&#8226;&#32; <a href="/wiki/%C5%A0ablon:Nukleobaze,_nukleozidi,_i_nukleotidi-lat" title="Šablon:Nukleobaze, nukleozidi, i nukleotidi-lat">Nukleobaze</a>/<a href="/w/index.php?title=%C5%A0ablon:Nukleinske_kiseline-lat&amp;action=edit&amp;redlink=1" class="new" title="Šablon:Nukleinske kiseline-lat (stranica ne postoji)">Nukleinske kiseline</a></div></td></tr></tbody></table></div> <!-- NewPP limit report Parsed by mw‐web.eqiad.main‐7d588db968‐smmj7 Cached time: 20241105022459 Cache expiry: 2592000 Reduced expiry: false Complications: [] CPU time usage: 0.143 seconds Real time usage: 0.462 seconds Preprocessor visited node count: 1541/1000000 Post‐expand include size: 22462/2097152 bytes Template argument size: 3384/2097152 bytes Highest expansion depth: 16/100 Expensive parser function count: 0/500 Unstrip recursion depth: 0/20 Unstrip post‐expand size: 9183/5000000 bytes Lua time usage: 0.058/10.000 seconds Lua memory usage: 928287/52428800 bytes Number of Wikibase entities loaded: 0/400 --> <!-- Transclusion expansion time report (%,ms,calls,template) 100.00% 149.555 1 -total 54.43% 81.399 1 Šablon:Proteinske_teme-lat 52.43% 78.419 1 Šablon:Navbox 42.00% 62.807 1 Šablon:Reflist 15.07% 22.539 1 Šablon:VoetBiochemistry3rd 13.89% 20.778 2 Šablon:Citation/core 13.16% 19.681 1 Šablon:Cite_book 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