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Saturday, November 23, 2024</div></section><div id="section-2" class="main-body"> <script src="/javascripts/pages/article.js"></script> <div id="breadcrumbs" class="breadcrumbs"><a class="" href="/">Home</a> » <a class="" href="/topics">Topics</a> » Science</div> <div class="box1 article-topic"> <div class="records"> <h1 class="page-title"> Science <div class="rss"> <a href="/rss/topic/110-science"> <img alt="Science RSS Feed" height="16" width="16" loading="lazy" src="/images/icons/rss.gif" /> RSS </a> </div> </h1> <article class="record article-summary "> <div class="image"><a title="Machine learning links microbiome composition to bacterial load" class="url" rel="" target="" href="https://www.bioworld.com/articles/714819-machine-learning-links-microbiome-composition-to-bacterial-load"><img width="650" height="488" alt="Illustration of gut bacteria on scales being evaluated by AI chip" title="Illustration of gut bacteria on scales being evaluated by AI chip" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BWS/BWS-source/EMBL-Bork-Gut-hero.jpg?height=488&t=1731686298&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Gastrointestinal</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714819-machine-learning-links-microbiome-composition-to-bacterial-load">Machine learning links microbiome composition to bacterial load</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 22, 2024</div> <div class="author article-summary__author">By <a href="/authors/595-mar-de-miguel">Mar de Miguel</a></div> <div class="comment-count article-summary__comment-count"><a title="Machine learning links microbiome composition to bacterial load" class="more" href="https://www.bioworld.com/articles/714819-machine-learning-links-microbiome-composition-to-bacterial-load#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Many studies have linked the presence of specific bacteria to various diseases. But a general overgrowth of gut bacteria can be a symptom of different conditions, including colorectal cancer and inflammatory bowel disease. <br /></div><a title="Machine learning links microbiome composition to bacterial load" class="more" href="https://www.bioworld.com/articles/714819-machine-learning-links-microbiome-composition-to-bacterial-load">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="More than 100M cells included in the human cell atlas" class="url" rel="" target="" href="https://www.bioworld.com/articles/714679-more-than-100m-cells-included-in-the-human-cell-atlas"><img width="650" height="488" alt="D-rendered image showing atlas of human embryonic skeletal development" title="D-rendered image showing atlas of human embryonic skeletal development" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BWS/BWS-source/Embryonic-skeletal-development-hero-11-21.jpg?height=488&t=1732207101&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Drug design, drug delivery & technologies</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714679-more-than-100m-cells-included-in-the-human-cell-atlas">More than 100M cells included in the human cell atlas</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 21, 2024</div> <div class="author article-summary__author">By <a href="/authors/595-mar-de-miguel">Mar de Miguel</a></div> <div class="comment-count article-summary__comment-count"><a title="More than 100M cells included in the human cell atlas" class="more" href="https://www.bioworld.com/articles/714679-more-than-100m-cells-included-in-the-human-cell-atlas#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">An international consortium of thousands of scientists is creating the Human Cell Atlas, a three-dimensional map of all the cells in the body. The goal is to understand all the cells that make up human tissues, organs and systems, which will enable multiple medical applications. This collection of cell maps is openly available for navigation at single-cell resolution, identified through omics analyses that reveal the tridimensional distribution of each cell.<br /></div><a title="More than 100M cells included in the human cell atlas" class="more" href="https://www.bioworld.com/articles/714679-more-than-100m-cells-included-in-the-human-cell-atlas">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Holistic strategies needed to diagnose and treat endometriosis" class="url" rel="" target="" href="https://www.bioworld.com/articles/714613-holistic-strategies-needed-to-diagnose-and-treat-endometriosis"><img width="650" height="488" alt="Woman holding stomach with inflammation" title="Woman holding stomach with inflammation" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Inflammatory/Woman-holding-stomach-with-inflammation.jpg?height=488&t=1732047546&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Healing the health divide</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714613-holistic-strategies-needed-to-diagnose-and-treat-endometriosis">Holistic strategies needed to diagnose and treat endometriosis</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 19, 2024</div> <div class="author article-summary__author">By <a href="/authors/49-tamra-sami">Tamra Sami</a></div> <div class="comment-count article-summary__comment-count"><a title="Holistic strategies needed to diagnose and treat endometriosis" class="more" href="https://www.bioworld.com/articles/714613-holistic-strategies-needed-to-diagnose-and-treat-endometriosis#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Endometriosis has been woefully under-recognized in the medical community, and consequently, the delay between onset and diagnosis is often quite long, with some women waiting up to 12 years for a diagnosis.<br /></div><a title="Holistic strategies needed to diagnose and treat endometriosis" class="more" href="https://www.bioworld.com/articles/714613-holistic-strategies-needed-to-diagnose-and-treat-endometriosis">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="The science of gender-based medicine: many reasons, many manifestations" class="url" rel="" target="" href="https://www.bioworld.com/articles/714429-the-science-of-gender-based-medicine-many-reasons-many-manifestations"><img width="650" height="488" alt="X/Y chromosomes" title="X/Y chromosomes" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BWS/BWS-source/Klinefelter-hero.jpg?height=488&t=1669385922&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Healing the health divide</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714429-the-science-of-gender-based-medicine-many-reasons-many-manifestations">The science of gender-based medicine: many reasons, many manifestations</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 14, 2024</div> <div class="author article-summary__author">By <a href="/authors/2-anette-breindl">Anette Breindl</a></div> <div class="comment-count article-summary__comment-count"><a title="The science of gender-based medicine: many reasons, many manifestations" class="more" href="https://www.bioworld.com/articles/714429-the-science-of-gender-based-medicine-many-reasons-many-manifestations#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">At the BioFuture 2024 conference held in New York in November, Seema Kumar, the CEO of Cure, described women’s health as something that has been directed at the “bikini area.” That “bikini” bias extended to both diseases and their causes – women’s health covered the breasts and reproductive system, and its causes were hormonal. Both concepts are far too narrow.<br /></div><a title="The science of gender-based medicine: many reasons, many manifestations" class="more" href="https://www.bioworld.com/articles/714429-the-science-of-gender-based-medicine-many-reasons-many-manifestations">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Healing a health divide (that’s long overdue)" class="url" rel="" target="" href="https://www.bioworld.com/articles/714428-healing-a-health-divide-thats-long-overdue"><img width="650" height="488" alt="Group of multigenerational, multiracial women" title="Group of multigenerational, multiracial women" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Misc/Group-of-multigenerational-multiracial-women.jpg?height=488&t=1731603262&width=650" /></a></div> <div class="article-summary__details has-image"> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714428-healing-a-health-divide-thats-long-overdue">Healing a health divide (that’s long overdue)</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 14, 2024</div> <div class="author article-summary__author">By <a href="/authors/1-lynn-yoffee">Lynn Yoffee</a></div> <div class="comment-count article-summary__comment-count"><a title="Healing a health divide (that’s long overdue)" class="more" href="https://www.bioworld.com/articles/714428-healing-a-health-divide-thats-long-overdue#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">It’s difficult to fathom that the health of half the world’s population is underserved. But it’s a hard truth. There are many conditions that disproportionately impact women. Other conditions and diseases affect women in different ways than men. Decades of research excluding women from clinical trials and investment decisions in male-dominated board rooms have ignored these facts. Though an increasing number of women are now managing investments and driving the research, it’s all still woefully behind. In <em>BioWorld</em>’s new report, Healing the health divide, we’ve highlighted the disparities.<br /></div><a title="Healing a health divide (that’s long overdue)" class="more" href="https://www.bioworld.com/articles/714428-healing-a-health-divide-thats-long-overdue">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Extrachromosomal DNA acts as joker for cancer cells " class="url" rel="" target="" href="https://www.bioworld.com/articles/714456-extrachromosomal-dna-acts-as-joker-for-cancer-cells"><img width="650" height="488" alt="Illustration of ecDNA inheritance in cancer" title="Illustration of ecDNA inheritance in cancer" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BWS/BWS-source/stanford-ecdna-11-11.jpg?height=488&t=1731345576&width=650" /></a></div> <div class="article-summary__details has-image"> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714456-extrachromosomal-dna-acts-as-joker-for-cancer-cells">Extrachromosomal DNA acts as joker for cancer cells </a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 13, 2024</div> <div class="author article-summary__author">By <a href="/authors/595-mar-de-miguel">Mar de Miguel</a></div> <div class="comment-count article-summary__comment-count"><a title="Extrachromosomal DNA acts as joker for cancer cells " class="more" href="https://www.bioworld.com/articles/714456-extrachromosomal-dna-acts-as-joker-for-cancer-cells#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Cancer therapies can eliminate specific tumors based on their genetic content. However, some cancer cells survive. How do they do it? Part of the answer lies in extrachromosomal DNA (ecDNA), an ace up the tumors’ sleeve to adapt and evade attack. Three simultaneous studies in the journal <em>Nature</em> lay all the cards on the table, revealing ecDNAs’ content, their origin, their inheritance, their influence in cancer, and a way to combat them.<br /></div><a title="Extrachromosomal DNA acts as joker for cancer cells " class="more" href="https://www.bioworld.com/articles/714456-extrachromosomal-dna-acts-as-joker-for-cancer-cells">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Quiescent, but not quiet, cancer stem cells in glioblastoma relapse" class="url" rel="" target="" href="https://www.bioworld.com/articles/714462-quiescent-but-not-quiet-cancer-stem-cells-in-glioblastoma-relapse"><img width="650" height="488" alt="3D illustration of brain cancer" title="3D illustration of brain cancer" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Cancer/3d-medically-accurate-human-brain-tumor.jpg?height=488&t=1731428528&width=650" /></a></div> <div class="article-summary__details has-image"> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714462-quiescent-but-not-quiet-cancer-stem-cells-in-glioblastoma-relapse">Quiescent, but not quiet, cancer stem cells in glioblastoma relapse</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 13, 2024</div> <div class="author article-summary__author">By <a href="/authors/595-mar-de-miguel">Mar de Miguel</a></div> <div class="comment-count article-summary__comment-count"><a title="Quiescent, but not quiet, cancer stem cells in glioblastoma relapse" class="more" href="https://www.bioworld.com/articles/714462-quiescent-but-not-quiet-cancer-stem-cells-in-glioblastoma-relapse#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Six main cell types form glioblastomas, the most aggressive brain cancer due to its high rate of recurrence. Of these six, quiescent cancer stem cells are responsible for resistance to therapy and the reappearance of the tumor, according to a study that identified the six groups and highlighted the importance of these stem cells for the design of more effective therapies.<br /></div><a title="Quiescent, but not quiet, cancer stem cells in glioblastoma relapse" class="more" href="https://www.bioworld.com/articles/714462-quiescent-but-not-quiet-cancer-stem-cells-in-glioblastoma-relapse">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Extrachromosomal DNA acts as joker for cancer cells " class="url" rel="" target="" href="https://www.bioworld.com/articles/714423-extrachromosomal-dna-acts-as-joker-for-cancer-cells"><img width="650" height="488" alt="Illustration of ecDNA inheritance in cancer" title="Illustration of ecDNA inheritance in cancer" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BWS/BWS-source/stanford-ecdna-11-11.jpg?height=488&t=1731345576&width=650" /></a></div> <div class="article-summary__details has-image"> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714423-extrachromosomal-dna-acts-as-joker-for-cancer-cells">Extrachromosomal DNA acts as joker for cancer cells </a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 12, 2024</div> <div class="author article-summary__author">By <a href="/authors/595-mar-de-miguel">Mar de Miguel</a></div> <div class="comment-count article-summary__comment-count"><a title="Extrachromosomal DNA acts as joker for cancer cells " class="more" href="https://www.bioworld.com/articles/714423-extrachromosomal-dna-acts-as-joker-for-cancer-cells#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Cancer therapies can eliminate specific tumors based on their genetic content. However, some cancer cells survive. How do they do it? Part of the answer lies in extrachromosomal DNA (ecDNA), an ace up the tumors’ sleeve to adapt and evade attack. Three simultaneous studies in the journal <em>Nature</em> lay all the cards on the table, revealing ecDNAs’ content, their origin, their inheritance, their influence in cancer, and a way to combat them.<br /></div><a title="Extrachromosomal DNA acts as joker for cancer cells " class="more" href="https://www.bioworld.com/articles/714423-extrachromosomal-dna-acts-as-joker-for-cancer-cells">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Less microglia activity may improve APOE4’s effect in Alzheimer’s" class="url" rel="" target="" href="https://www.bioworld.com/articles/714228-less-microglia-activity-may-improve-apoe4s-effect-in-alzheimers"><img width="650" height="488" alt="Illustration of Microglia cells (red) in Alzheimer´s disease" title="Illustration of Microglia cells (red) in Alzheimer´s disease" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/Stock-images/Therapeutic-topics/Neurology/Microglia-cells-Alzheimers-disease.jpg?height=488&t=1731081969&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Neurology/psychiatric</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714228-less-microglia-activity-may-improve-apoe4s-effect-in-alzheimers">Less microglia activity may improve APOE4’s effect in Alzheimer’s</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 8, 2024</div> <div class="author article-summary__author">By <a href="/authors/595-mar-de-miguel">Mar de Miguel</a></div> <div class="comment-count article-summary__comment-count"><a title="Less microglia activity may improve APOE4’s effect in Alzheimer’s" class="more" href="https://www.bioworld.com/articles/714228-less-microglia-activity-may-improve-apoe4s-effect-in-alzheimers#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Reducing microglial activity in the presence of apolipoprotein E4 (APOE4) has uncovered a mechanism associated with the deposition of misfolded amyloid and tau in a novel mouse model of Alzheimer’s disease. By transplanting human neurons into the mouse brain and eliminating the mouse microglia, scientists at the Gladstone Institutes in San Francisco observed that amyloid and tau deposition was reduced. These results support therapeutic strategies that target APOE4 and microglia.<br /></div><a title="Less microglia activity may improve APOE4’s effect in Alzheimer’s" class="more" href="https://www.bioworld.com/articles/714228-less-microglia-activity-may-improve-apoe4s-effect-in-alzheimers">Read More</a> </div> </article> <article class="record article-summary "> <div class="image"><a title="Blocking CGRP in endometriosis: two birds with one stone?" class="url" rel="" target="" href="https://www.bioworld.com/articles/714198-blocking-cgrp-in-endometriosis-two-birds-with-one-stone"><img width="650" height="488" alt="Endometriosis" title="Endometriosis" border="0" loading="lazy" src="https://www.bioworld.com/ext/resources/BWS/BWS-library/Endometriosis.jpg?height=488&t=1705616846&width=650" /></a></div> <div class="article-summary__details has-image"> <div class="kicker article-summary__kicker">Endocrine/metabolic</div> <h2 class="headline article-summary__headline"><a href="https://www.bioworld.com/articles/714198-blocking-cgrp-in-endometriosis-two-birds-with-one-stone">Blocking CGRP in endometriosis: two birds with one stone?</a></h2> <div class="post-meta"> <div class="date article-summary__post-date">Nov. 7, 2024</div> <div class="author article-summary__author">By <a href="/authors/601-coia-dulsat">Coia Dulsat</a></div> <div class="comment-count article-summary__comment-count"><a title="Blocking CGRP in endometriosis: two birds with one stone?" class="more" href="https://www.bioworld.com/articles/714198-blocking-cgrp-in-endometriosis-two-birds-with-one-stone#comments-container">No Comments</a></div> </div> <div class="abstract article-summary__teaser">Researchers at Harvard Medical School have found that blocking the neuron-released peptide CGRP decreases pain sensitivity and reduces lesion size in endometriosis. Endometriosis is a painful, steroid-dependent inflammatory condition in which tissue similar to that of the endometrial lining grows and establishes outside the uterine mucosa.<br /></div><a title="Blocking CGRP in endometriosis: two birds with one stone?" class="more" href="https://www.bioworld.com/articles/714198-blocking-cgrp-in-endometriosis-two-birds-with-one-stone">Read More</a> </div> </article> </div> <div class="pager"> <div role="navigation" aria-label="Pagination" class="pagination"><span class="previous_page disabled" aria-disabled="true">Previous</span> <em class="current" aria-label="Page 1" aria-current="page">1</em> <a rel="next" aria-label="Page 2" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=2">2</a> <a aria-label="Page 3" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=3">3</a> <a aria-label="Page 4" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=4">4</a> <a aria-label="Page 5" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=5">5</a> <a aria-label="Page 6" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=6">6</a> <a aria-label="Page 7" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=7">7</a> <a aria-label="Page 8" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=8">8</a> <a aria-label="Page 9" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=9">9</a> <span class="gap">…</span> <a aria-label="Page 164" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=164">164</a> <a aria-label="Page 165" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=165">165</a> <a class="next_page" rel="next" href="/articles/topic/110-bioworld-biome-bioworld-asia?page=2">Next</a></div> </div> </div> </div><aside class="main-interior-sidebar"><div class="main-interior-sidebar__column"><div id="article-recommendations"></div> </div><div class="main-interior-sidebar__column"><section class="popular-stories "> <h1 class="popular-stories__title">Popular Stories</h1><ul class="popular-stories__items"> <li class="popular-stories__item"> <article class="popular-stories__article popular-stories--article"><div class="popular-stories__details popular-stories__details-1"><h1 class="popular-stories__headline"><a class="popular-stories__article-title-link" href="https://www.bioworld.com/articles/432891-todays-news-in-brief">Today's news in brief</a></h1><div class="popular-stories__topics"><a class="popular-stories__topic-link" href="/topics/84-bioworld">BioWorld</a></div><div class="popular-stories__teaser"><em>BioWorld</em> briefs for Nov. 22, 2024.</div></div></article> </li> <li class="popular-stories__item"> <article class="popular-stories__article popular-stories--article"><div class="popular-stories__details popular-stories__details-1"><h1 class="popular-stories__headline"><a class="popular-stories__article-title-link" href="https://www.bioworld.com/articles/699574-todays-news-in-brief">Today's news in brief</a></h1><div class="popular-stories__topics"><a class="popular-stories__topic-link" href="/topics/85-bioworld-medtech">BioWorld MedTech</a></div><div class="popular-stories__teaser"><em>BioWorld MedTech</em> briefs for November 21, 2024.</div></div></article> </li> <li class="popular-stories__item"> <article class="popular-stories__article -has-image popular-stories--article"><figure class="popular-stories__image"><a class="popular-stories__thumbnail-link" data-eventname="popular-stories" data-eventcategory="click" data-eventaction="popular-stories-image" data-eventlabel="https://www.bioworld.com/articles/714048-j-and-js-ottava-robotic-system-approved-for-us-pivotal-trial" href="https://www.bioworld.com/articles/714048-j-and-js-ottava-robotic-system-approved-for-us-pivotal-trial"><img class="popular-stories__image-thumb" alt="Da Vinci Xi robot - Intuitive Surgical" title="Da Vinci Xi robot - Intuitive Surgical" width="640" height="355" loading="lazy" src="https://www.bioworld.com/ext/resources/BMT-source/2023/1-26--Da-Vinci-Xi-robot-Intuitive-Surgical.png?height=355&t=1699482891&width=640" /></a></figure><div class="popular-stories__details popular-stories__details-1"><h1 class="popular-stories__headline"><a class="popular-stories__article-title-link" href="https://www.bioworld.com/articles/714048-j-and-js-ottava-robotic-system-approved-for-us-pivotal-trial">J&J’s Ottava robotic system approved for US pivotal trial</a></h1><div class="popular-stories__topics"><a class="popular-stories__topic-link" href="/topics/85-bioworld-medtech">BioWorld MedTech</a></div><div class="popular-stories__teaser">Johnson & Johnson received U.S. FDA investigational device exemption to begin the pivotal clinical trial for the Ottava robotic surgical system. 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