Total Pancreatectomy - Islet Auto Transplant (TP-IAT) Clinic

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title="Gastroenterology" href="/list-of-clinics/gastroenterology">Gastroenterology</a><a title="Organ Transplant" href="/list-of-clinics/organ-transplant">Organ Transplant</a> </div> <h1 class="hero-title long-hero-title display1"> Total Pancreatectomy - Islet Auto-Transplant (TP-IAT) Clinic </h1> </div> </div> </div><div class="component clinic-ctas container margin-bottom-24"> <div class="component-content"> <div> <div class="request-appointment" data-modal-text="To request an appointment, please give us a call at (415) 353-1473."> <span class="icon-ui-calendar"></span>Request appointment </div> </div> <div> <a href="/clinics/total-pancreatectomy-islet-auto-transplant-tp-iat-clinic/refer" target="_self" class="refer-patient"> <span class="icon-ui-refer"></span>Refer a patient </a> </div> <div> <a href="/second-opinion" target="_self" class="get-second-opinion"> <span class="icon-ui-clipboard"></span>Get a second opinion </a> </div> <div class="clinic-phone-num"> <span class="icon-ui-phone"></span> (415) 353-1473 </div> </div> </div><div class="component share-print-email container"> <div class="component-content"> <div class="share-component"> <a aria-label="Print Page" href="#" rel="nofollow" class="icon-ui-print" title="Print"></a> <a aria-label="Share Page" data-email-body="Thought you might want to see this:" class="icon-ui-share" data-email-body="Thought you might want to see this:" data-email-subject="Take a look at this link from UCSF"></a> </div> <div class="clearfix"></div> </div> </div><div class="component clinic-intro container"> <div class="component-content"> <div class="clinic-intro-content"> <div class="clinic-intro-text rich-text font-larger "> <p>The <strong>UCSF Total Pancreatectomy – Islet Auto-Transplant (TP-IAT) Clinic</strong> is the only facility west of the Mississippi to offer islet auto-transplantation as a way to minimize diabetes after a total pancreatectomy (surgical removal of the pancreas). This innovative procedure helps alleviate the pain caused by chronic pancreatitis while preserving the patient's ability to secrete insulin and reducing the risk of surgically induced diabetes. It can also be used to treat patients with relapsing acute pancreatitis.</p> <p>Chronic pancreatitis can severely limit a patient's quality of life. Managing the pain is often difficult, and patients are frequently too disabled to work. Severely ill patients have traditionally been treated by removing the pancreas, but this leaves them diabetic and dependent on insulin injections.</p> <p>A total pancreatectomy followed by an islet auto-transplantation is a complicated procedure that requires expertise and training found at only a select few medical centers in the world. The depth and breadth of transplant experience at UCSF has played a vital role in allowing us to perform islet auto-transplantation safely and effectively.</p> <p>The technique involves harvesting functioning islets (the cells that make insulin) from the patient's diseased pancreas and then infusing them into the portal vein, where they migrate to the liver. The islet auto-transplant technique is a modification of one used to manage severe insulin-dependent (type 1) diabetes, in which islets are isolated from a deceased donor’s pancreas. In chronic pancreatitis, the patient's own islets are used, eliminating the risk of tissue rejection.</p> <div class="continue-reading"><span class="read-more btn btn-drawer"><a>Continue reading </a></span><div> <h2>Our Outcomes</h2> <p>At UCSF, more than 100 patients have undergone total pancreatectomy with islet auto-transplantation since 2006. All have survived, and more than half did not require insulin after the procedure. In keeping with results from the few other institutions using the technique, pain medication has been substantially reduced for 70 to 80 percent of UCSF patients, and 40 to 50 percent have been able to stop taking pain medication completely.</p> <h2>Innovation and Research</h2> <ul> <li>Member, Collaborative Islet Transplant Registry (CITR)</li> <li>Member, Clinical Islet Transplantation (CIT) Consortium</li> </ul> <p></div></div></p> </div> <div class="click-intro-referral "> <p class="font-smaller"> <span class="icon-ui-info"></span> Doctor referral required </p> </div> </div> </div> </div> <div class="component content container"> <div class="component-content"> <div class="component map-module col-xs-12"> <div class="component-content"> <div class="map-title"> <h2 class="heading1 title-anchor"> Our locations </h2> <div class="view-all"> </div> </div> <div class="map-container"data-api-call="/ucsfapi/map/getmapdata" data-query-string-param="datasourceid" 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<p class="font-larger doctor-class"> MD, PhD </p> <span class="doctor-simple-title"> Bariatric and transplant surgeon </span> </div> </a> </li> <li> <a href="/providers/dr-umesh-masharani"> <img loading="lazy" src="/-/media/project/ucsf/ucsf-health/doctor/card/dr-umesh-masharani-md-320x320-2x.jpg?h=526&w=526&rev=d2754e1292c04fc9929552d2fe5064dd&hash=F835E97EB8E9FAA0CDC9BEDE70FEE634" alt="" width="640" height="640"> <div> <h3 class="doctor-name"> Umesh Masharani </h3> <p class="font-larger doctor-class"> MBBS </p> <span class="doctor-simple-title"> Endocrinologist </span> </div> </a> </li> </ul> </div> </div> </div> <div class="component accolades col-xs-12"> <div class="component-content"> <h2 class="heading1">Awards & recognition</h2> <ul> <li class="component accolade"> <div class="component-content"> <div class="image-wrapper"> <img loading="lazy" 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cards-component col-xs-12"> <div class="component-content"> <div class="patient-services-header"> <h2 class="heading1 title-anchor"> Support services </h2> <div class="view-all"> </div> </div> <div class="cards"> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/case-management-and-social-work" class="phantom-link" title="Case Management & Social Work"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-health/service/hero/case-management-and-social-work-2x.jpg?h=376&w=973&rev=69b056ca73c648d799f509256f5cc501&hash=4E0624CD2EAC134D105E92237A0E9487" alt="""" width="2880" height="1112" /> <div class="field-icon patient-resource"> <div class="eyebrow"> Patient Resource </div> </div> <p class="font-larger"> Case Management & Social Work </p> <p> Connect with a team that can help you find resources, solve problems and advocate for you during treatment at UCSF. </p> <span class="field-read-more-link"><span class="include-ucsf-arrow"></span></span> </div> </div> </div> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/mindfulness-based-stress-reduction-class" class="phantom-link" title="Mindfulness-Based Stress Reduction Class"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-health/service/hero/mindfulness-based-stress-reduction-class-2x.jpg?h=376&w=973&rev=878d128dd6ee4dca9e87bb797b090ff3&hash=8926E46901B55372A1E52876153CF9FF" alt="" width="2880" height="1112" /> <div class="field-icon class"> <div class="eyebrow"> Class </div> </div> <p class="font-larger"> Mindfulness-Based Stress Reduction Class </p> <p> This eight-week class teaches mindfulness practices that can reduce stress and improve your overall health, such as meditation and body awareness. </p> <span class="field-read-more-link"><span class="include-ucsf-arrow"></span></span> </div> </div> </div> <div class="card"> <div class="component-content"> <div 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</div><div class="component plan-your-visit cards-component col-xs-12"> <div class="component-content"> <div> <h2 class="heading1 title-anchor"> Plan your visit </h2> <div class="view-all"> <a title="See insurance plans accepted" href="/billing-and-insurance/health-insurance">See insurance plans accepted</a> </div> </div> <div class="component guide-card col-xs-12 printable-component"> <div class="component-content"> <div class="guide-heading-section"> <div class="eyebrow" id="862FA2F8B48B44FA8FC410846B755E85"> Preparing for your appointment </div> <h2 class="heading1 font-strict title-anchor">What to Bring</h2> <div class="share-component"> <a href="#" rel="nofollow" class="icon-ui-print single-print-component" title="Print Guide Card"></a> <a class="icon-ui-share" data-email-body="Thought you might want to see this:" data-email-subject="Take a look at this link from UCSF" title="Share Guide Card"></a> </div> <div class="clearfix"></div> </div> <div class="guide-list-section"> <ul> <li>Photo I.D.</li> <li>Health insurance card</li> <li>Insurance authorization, if required</li> <li>Doctor's referral, if required</li> <li>Recent test results related to your condition</li> <li>List of your medications, including dosages, plus any you're allergic to</li> <li>List of questions you may have</li> <li>Device or paper for taking notes</li> </ul> </div> </div> </div> <div class="cards cards-small"> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/international-services" class="phantom-link" title="International Services"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-health/service/hero/international-services-2x.jpg?h=276&w=714&rev=d81f5a78eb8b40b4a003a71c76eb0f23&hash=4DE657BB47B338245361F2BEFE7631B2" alt="" width="2880" height="1112" /> <p> International Services </p> <p> If you live outside the United States and are coming to UCSF for medical treatment, our patient liaisons can help coordinate all aspects of your 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making your UCSF doctor’s appointment as stress-free and productive as possible. </p> <span class="field-read-more-link"> <span class="include-ucsf-link">Learn more</span> </span> </div> </div> </div> </div> </div> </div><div class="component clinic-cards cards-component col-xs-12"> <div class="component-content twoOrLess"> <div> <h2 class="heading1 title-anchor"> Related clinics </h2> <div class="view-all"> </div> </div> <div class="cards"> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/clinics/pancreas-transplant-services" target="_self" class="phantom-link" title="Pancreas Transplant Services"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-health/clinic/street/400-parnassus-avenue-2x.jpg?h=376&w=974&rev=96b1b4e7a30e4ac3b2a91cb4321513de&hash=2D6C2DC82E28F9A67477991A33B70B32" alt="" width="2880" height="1112"/> <div class="field-icon"> <a href="https://www.google.com/maps/place/400 Parnassus Ave.+San Francisco+CA+94143" target="_blank"> <span class="icon-ui-location"></span> </a> </div> <p class="font-larger"> Pancreas Transplant Services </p> <p> 400 Parnassus Ave., Seventh Floor <br> San Francisco, CA 94143 </p> <div class="field-read-more-link"> <div class="font-smaller"> <span class="icon-ui-phone"></span>(415) 353-1551 </div> <div class="font-smaller"> <span class="icon-decorative-hours"></span>M-F, 8 a.m. - 5 p.m. </div> </div> </div> </div> </div> </div> </div> </div> <div class="component twoup-promo col-xs-12"> <div class="component-content"> <div class="component twoup-promo-link col-xs-12"> <div class="component-content"> <h2 class="heading1 field-headline">Do you need pediatric care?</h2><div class="field-link"><a href="https://www.ucsfbenioffchildrens.org/" rel="noopener noreferrer" data-variantitemid="{A519A438-D0A5-4ED3-813F-DD17CE0FA497}" data-variantfieldname="Link" target="_blank">UCSF Benioff Children's Hospitals</a></div><div class="field-icon"><img src="/-/media/project/ucsf/ucsf-health/logo/ucsf-benioff-childrens-hospitals.svg?h=78&iar=0&w=272&rev=f040908e31d14e999c060a91eec6e26c&hash=A42CF83A91C622B387AEFF58A9798CBC" alt="UCSF Benioff Children's Hospitals" width="272" height="78" data-variantitemid="{A519A438-D0A5-4ED3-813F-DD17CE0FA497}" data-variantfieldname="Icon" /></div> </div> </div> <div class="component twoup-promo-contact col-xs-12"> <div class="component-content"> <h2 class="heading1 field-headline">Can't find what you're looking for?</h2><p class="font-larger field-promo-text"><p>UCSF Help Center</p></p><div class="field-phone"><span class='icon-ui-phone'></span> (888) 689-8273</div> <div class="field-email"> <span class='icon-ui-mail'></span><a href="/cdn-cgi/l/email-protection#f6849390938484979ad8959398829384b683958590d8939283"><span class="__cf_email__" data-cfemail="3547505350474754591b56505b41504775405646531b505140">[email protected]</span></a> </div> </div> </div> </div> </div> </div> </div> </div> </main>   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