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Quality of life (QoL) refers to the perception of an individual's life in the context of the system of culture and values in which they live. Aim: The aim of the study was to determine the distribution of cognitive disorders in people with MS. Methods: The prospective study included 135 participants with MS and 50 healthy participants. Participants were divided into three groups: the first group consisted of 85 participants where the disease lasted longer than one year, the second group consisted of 50 participants with newly diagnosed MS, the third group consisted of 50 healthy participants. The instruments of clinical assessment were: Extended Disability Score in Multiple Sclerosis Patients, Mini Mental Status, Beck Depression Scale, and Quality of Life Scale (SF-36, Contemporary Health Survey). Results: The quality of life related to health is impaired in the physical, mental dimension and overall quality of life. In the first group of participants, 62% had mild depression, and in the second group 38% of participants, while more severe forms were recorded in 16% of participants in both groups. As depression increases, the quality of life decreases in all measured dimensions, which would mean that depression negatively affects the quality of life. The results of all dimensions as well as the overall quality of life score are worse with the increase in the degree of clinical disability, for both groups of study patients. Conclusion: Quality of life is impaired in MS patients, and a higher degree of clinical disability and an increase in depressive disorder are predictors of deteriorating quality of life in MS patients.","publication_date":"2020,,","publication_name":"Medical Archives","grobid_abstract_attachment_id":"84243210"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Contributing Factors to the Quality of Life in Multiple Sclerosis","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [33504206]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" 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data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="25774353" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/25774353/Relation_of_cognitive_impairment_and_depression_to_quality_of_life_in_multiple_sclerosis_patients">Relation of cognitive impairment and depression to quality of life in multiple sclerosis patients</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31505417" href="https://independent.academia.edu/SolariAldo">Aldo Solari</a></div><p class="ds-related-work--metadata ds2-5-body-xs">The Italian Journal of 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href="https://www.academia.edu/18978866/Quality_of_life_assessment_in_patients_with_multiple_sclerosis">Quality of life assessment in patients with multiple sclerosis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="39126505" href="https://kg.academia.edu/JelenaDrulovic">Jelena Drulovic</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Vojnosanitetski pregled, 2009</p><p class="ds-related-work--abstract ds2-5-body-sm">Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system. 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js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/47138557/Depression_and_quality_of_life_in_multiple_sclerosis">Depression and quality of life in multiple sclerosis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="37015453" href="https://independent.academia.edu/HenrietteL%C3%B6fflerstastka">Henriette Löffler-stastka</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Acta Neurologica Scandinavica, 2001</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Depression and quality of life in multiple sclerosis","attachmentId":66390327,"attachmentType":"pdf","work_url":"https://www.academia.edu/47138557/Depression_and_quality_of_life_in_multiple_sclerosis","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/47138557/Depression_and_quality_of_life_in_multiple_sclerosis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="23380839" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/23380839/Deterioration_in_the_health_related_quality_of_life_of_persons_with_multiple_sclerosis_the_possible_warning_signs">Deterioration in the health-related quality of life of persons with multiple sclerosis: the possible warning signs</a><div 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class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/23380839/Deterioration_in_the_health_related_quality_of_life_of_persons_with_multiple_sclerosis_the_possible_warning_signs"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="107428954" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/107428954/Cognitive_function_and_quality_of_life_in_multiple_sclerosis_patients_a_cross_sectional_study">Cognitive function and quality of life in multiple sclerosis patients: a cross-sectional study</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="177640898" href="https://independent.academia.edu/RobertoCutajar">Roberto Cutajar</a></div><p class="ds-related-work--metadata ds2-5-body-xs">BMC Neurology, 2011</p><p class="ds-related-work--abstract ds2-5-body-sm">Background Nearly half of all patients diagnosed with multiple sclerosis (MS) will develop cognitive dysfunction. Studies highlighted from no/weak impact to a strong impact of cognitive impairment on quality of life (QoL). The aim of this study was to assess the impact of cognitive dysfunction on self-reported QoL in MS patients while considering key confounding factors. Methods Design: cross-sectional study. Inclusion criteria: MS patients of any disease subtype. Data collection: sociodemographic (age, gender, marital status, education level, and occupational activity) and clinical data (MS subtype, disease duration); MS disability (Expanded Disability Status Scale, EDSS); depression (Beck Depression Inventory); fatigue (Modified Fatigue Impact Scale); QoL (SF36 and MusiQoL); and neuropsychological performance (Brief Repeatable Battery of Neuropsychological Tests, BRB-N). Statistical analysis: multiple linear regressions (forward-stepwise selection). Results One hundred and twenty-...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Cognitive function and quality of life in multiple sclerosis patients: a cross-sectional study","attachmentId":106097756,"attachmentType":"pdf","work_url":"https://www.academia.edu/107428954/Cognitive_function_and_quality_of_life_in_multiple_sclerosis_patients_a_cross_sectional_study","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/107428954/Cognitive_function_and_quality_of_life_in_multiple_sclerosis_patients_a_cross_sectional_study"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="63251047" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/63251047/Is_the_Concept_of_Quality_of_Life_Relevant_for_Multiple_Sclerosis_Patients_with_Cognitive_Impairment_Preliminary_Results_of_a_Cross_Sectional_Study">Is the Concept of Quality of Life Relevant for Multiple Sclerosis Patients with Cognitive Impairment? Preliminary Results of a Cross-Sectional Study</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="45020010" href="https://independent.academia.edu/PascalAuquier">Pascal Auquier</a></div><p class="ds-related-work--metadata ds2-5-body-xs">PLoS ONE, 2012</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Is the Concept of Quality of Life Relevant for Multiple Sclerosis Patients with Cognitive Impairment? 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