CINXE.COM

<!DOCTYPE html> <html class="client-nojs vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-sticky-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-enabled skin-theme-clientpref-day vector-toc-available" lang="en" dir="ltr"> <head> <meta charset="UTF-8"> <title>Mladen Vranic - Wikipedia</title> <script>(function(){var className="client-js vector-feature-language-in-header-enabled vector-feature-language-in-main-page-header-disabled vector-feature-sticky-header-disabled vector-feature-page-tools-pinned-disabled vector-feature-toc-pinned-clientpref-1 vector-feature-main-menu-pinned-disabled vector-feature-limited-width-clientpref-1 vector-feature-limited-width-content-enabled vector-feature-custom-font-size-clientpref-1 vector-feature-appearance-pinned-clientpref-1 vector-feature-night-mode-enabled skin-theme-clientpref-day vector-toc-available";var cookie=document.cookie.match(/(?:^|; )enwikimwclientpreferences=([^;]+)/);if(cookie){cookie[1].split('%2C').forEach(function(pref){className=className.replace(new RegExp('(^| )'+pref.replace(/-clientpref-\w+$|[^\w-]+/g,'')+'-clientpref-\\w+( |$)'),'$1'+pref+'$2');});}document.documentElement.className=className;}());RLCONF={"wgBreakFrames":false,"wgSeparatorTransformTable":["",""],"wgDigitTransformTable":["",""],"wgDefaultDateFormat":"dmy", "wgMonthNames":["","January","February","March","April","May","June","July","August","September","October","November","December"],"wgRequestId":"709215eb-5c3a-4436-818f-f99a9f832601","wgCanonicalNamespace":"","wgCanonicalSpecialPageName":false,"wgNamespaceNumber":0,"wgPageName":"Mladen_Vranic","wgTitle":"Mladen Vranic","wgCurRevisionId":1256330528,"wgRevisionId":1256330528,"wgArticleId":41604556,"wgIsArticle":true,"wgIsRedirect":false,"wgAction":"view","wgUserName":null,"wgUserGroups":["*"],"wgCategories":["CS1 maint: multiple names: authors list","Articles with short description","Short description matches Wikidata","Autobiographical articles from June 2017","Articles lacking reliable references from June 2017","All articles lacking reliable references","Articles with multiple maintenance issues","Articles with hCards","Articles containing Croatian-language text","1930 births","2019 deaths","Canadian diabetologists","Croatian emigrants to Canada", "Fellows of the Royal Society of Canada","Members of the Order of Ontario","Officers of the Order of Canada","Scientists from Toronto","Scientists from Zagreb","University of Zagreb alumni"],"wgPageViewLanguage":"en","wgPageContentLanguage":"en","wgPageContentModel":"wikitext","wgRelevantPageName":"Mladen_Vranic","wgRelevantArticleId":41604556,"wgIsProbablyEditable":true,"wgRelevantPageIsProbablyEditable":true,"wgRestrictionEdit":[],"wgRestrictionMove":[],"wgNoticeProject":"wikipedia","wgCiteReferencePreviewsActive":false,"wgFlaggedRevsParams":{"tags":{"status":{"levels":1}}},"wgMediaViewerOnClick":true,"wgMediaViewerEnabledByDefault":true,"wgPopupsFlags":0,"wgVisualEditor":{"pageLanguageCode":"en","pageLanguageDir":"ltr","pageVariantFallbacks":"en"},"wgMFDisplayWikibaseDescriptions":{"search":true,"watchlist":true,"tagline":false,"nearby":true},"wgWMESchemaEditAttemptStepOversample":false,"wgWMEPageLength":30000,"wgRelatedArticlesCompat":[],"wgEditSubmitButtonLabelPublish":true, "wgULSPosition":"interlanguage","wgULSisCompactLinksEnabled":false,"wgVector2022LanguageInHeader":true,"wgULSisLanguageSelectorEmpty":false,"wgWikibaseItemId":"Q16091666","wgCheckUserClientHintsHeadersJsApi":["brands","architecture","bitness","fullVersionList","mobile","model","platform","platformVersion"],"GEHomepageSuggestedEditsEnableTopics":true,"wgGETopicsMatchModeEnabled":false,"wgGEStructuredTaskRejectionReasonTextInputEnabled":false,"wgGELevelingUpEnabledForUser":false};RLSTATE={"ext.globalCssJs.user.styles":"ready","site.styles":"ready","user.styles":"ready","ext.globalCssJs.user":"ready","user":"ready","user.options":"loading","ext.cite.styles":"ready","skins.vector.search.codex.styles":"ready","skins.vector.styles":"ready","skins.vector.icons":"ready","jquery.makeCollapsible.styles":"ready","ext.wikimediamessages.styles":"ready","ext.visualEditor.desktopArticleTarget.noscript":"ready","ext.uls.interlanguage":"ready","wikibase.client.init":"ready","ext.wikimediaBadges": "ready"};RLPAGEMODULES=["ext.cite.ux-enhancements","site","mediawiki.page.ready","jquery.makeCollapsible","mediawiki.toc","skins.vector.js","ext.centralNotice.geoIP","ext.centralNotice.startUp","ext.gadget.ReferenceTooltips","ext.gadget.switcher","ext.urlShortener.toolbar","ext.centralauth.centralautologin","mmv.bootstrap","ext.popups","ext.visualEditor.desktopArticleTarget.init","ext.visualEditor.targetLoader","ext.echo.centralauth","ext.eventLogging","ext.wikimediaEvents","ext.navigationTiming","ext.uls.interface","ext.cx.eventlogging.campaigns","ext.cx.uls.quick.actions","wikibase.client.vector-2022","ext.checkUser.clientHints","ext.growthExperiments.SuggestedEditSession","wikibase.sidebar.tracking"];</script> <script>(RLQ=window.RLQ||[]).push(function(){mw.loader.impl(function(){return["user.options@12s5i",function($,jQuery,require,module){mw.user.tokens.set({"patrolToken":"+\\","watchToken":"+\\","csrfToken":"+\\"}); }];});});</script> <link rel="stylesheet" href="/w/load.php?lang=en&modules=ext.cite.styles%7Cext.uls.interlanguage%7Cext.visualEditor.desktopArticleTarget.noscript%7Cext.wikimediaBadges%7Cext.wikimediamessages.styles%7Cjquery.makeCollapsible.styles%7Cskins.vector.icons%2Cstyles%7Cskins.vector.search.codex.styles%7Cwikibase.client.init&only=styles&skin=vector-2022"> <script async="" src="/w/load.php?lang=en&modules=startup&only=scripts&raw=1&skin=vector-2022"></script> <meta name="ResourceLoaderDynamicStyles" content=""> <link rel="stylesheet" href="/w/load.php?lang=en&modules=site.styles&only=styles&skin=vector-2022"> <meta name="generator" content="MediaWiki 1.44.0-wmf.5"> <meta name="referrer" content="origin"> <meta name="referrer" content="origin-when-cross-origin"> <meta name="robots" content="max-image-preview:standard"> <meta name="format-detection" content="telephone=no"> <meta name="viewport" content="width=1120"> <meta property="og:title" content="Mladen Vranic - Wikipedia"> <meta property="og:type" content="website"> <link rel="preconnect" href="//upload.wikimedia.org"> <link rel="alternate" media="only screen and (max-width: 640px)" href="//en.m.wikipedia.org/wiki/Mladen_Vranic"> <link rel="alternate" type="application/x-wiki" title="Edit this page" href="/w/index.php?title=Mladen_Vranic&action=edit"> <link rel="apple-touch-icon" href="/static/apple-touch/wikipedia.png"> <link rel="icon" href="/static/favicon/wikipedia.ico"> <link rel="search" type="application/opensearchdescription+xml" href="/w/rest.php/v1/search" title="Wikipedia (en)"> <link rel="EditURI" type="application/rsd+xml" href="//en.wikipedia.org/w/api.php?action=rsd"> <link rel="canonical" href="https://en.wikipedia.org/wiki/Mladen_Vranic"> <link rel="license" href="https://creativecommons.org/licenses/by-sa/4.0/deed.en"> <link rel="alternate" type="application/atom+xml" title="Wikipedia Atom feed" href="/w/index.php?title=Special:RecentChanges&feed=atom"> <link rel="dns-prefetch" href="//meta.wikimedia.org" /> <link rel="dns-prefetch" href="//login.wikimedia.org"> </head> <body class="skin--responsive skin-vector skin-vector-search-vue mediawiki ltr sitedir-ltr mw-hide-empty-elt ns-0 ns-subject mw-editable page-Mladen_Vranic rootpage-Mladen_Vranic skin-vector-2022 action-view"><a class="mw-jump-link" href="#bodyContent">Jump to content</a> <div class="vector-header-container"> <header class="vector-header mw-header"> <div class="vector-header-start"> <nav class="vector-main-menu-landmark" aria-label="Site"> <div id="vector-main-menu-dropdown" class="vector-dropdown vector-main-menu-dropdown vector-button-flush-left vector-button-flush-right" > <input type="checkbox" id="vector-main-menu-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-main-menu-dropdown" class="vector-dropdown-checkbox " aria-label="Main menu" > <label id="vector-main-menu-dropdown-label" for="vector-main-menu-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-menu mw-ui-icon-wikimedia-menu"></span> <span class="vector-dropdown-label-text">Main menu</span> </label> <div class="vector-dropdown-content"> <div id="vector-main-menu-unpinned-container" class="vector-unpinned-container"> <div id="vector-main-menu" class="vector-main-menu vector-pinnable-element"> <div class="vector-pinnable-header vector-main-menu-pinnable-header vector-pinnable-header-unpinned" data-feature-name="main-menu-pinned" data-pinnable-element-id="vector-main-menu" data-pinned-container-id="vector-main-menu-pinned-container" data-unpinned-container-id="vector-main-menu-unpinned-container" > <div class="vector-pinnable-header-label">Main menu</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-main-menu.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-main-menu.unpin">hide</button> </div> <div id="p-navigation" class="vector-menu mw-portlet mw-portlet-navigation" > <div class="vector-menu-heading"> Navigation </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-mainpage-description" class="mw-list-item"><a href="/wiki/Main_Page" title="Visit the main page [z]" accesskey="z"><span>Main page</span></a></li><li id="n-contents" class="mw-list-item"><a href="/wiki/Wikipedia:Contents" title="Guides to browsing Wikipedia"><span>Contents</span></a></li><li id="n-currentevents" class="mw-list-item"><a href="/wiki/Portal:Current_events" title="Articles related to current events"><span>Current events</span></a></li><li id="n-randompage" class="mw-list-item"><a href="/wiki/Special:Random" title="Visit a randomly selected article [x]" accesskey="x"><span>Random article</span></a></li><li id="n-aboutsite" class="mw-list-item"><a href="/wiki/Wikipedia:About" title="Learn about Wikipedia and how it works"><span>About Wikipedia</span></a></li><li id="n-contactpage" class="mw-list-item"><a href="//en.wikipedia.org/wiki/Wikipedia:Contact_us" title="How to contact Wikipedia"><span>Contact us</span></a></li> </ul> </div> </div> <div id="p-interaction" class="vector-menu mw-portlet mw-portlet-interaction" > <div class="vector-menu-heading"> Contribute </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-help" class="mw-list-item"><a href="/wiki/Help:Contents" title="Guidance on how to use and edit Wikipedia"><span>Help</span></a></li><li id="n-introduction" class="mw-list-item"><a href="/wiki/Help:Introduction" title="Learn how to edit Wikipedia"><span>Learn to edit</span></a></li><li id="n-portal" class="mw-list-item"><a href="/wiki/Wikipedia:Community_portal" title="The hub for editors"><span>Community portal</span></a></li><li id="n-recentchanges" class="mw-list-item"><a href="/wiki/Special:RecentChanges" title="A list of recent changes to Wikipedia [r]" accesskey="r"><span>Recent changes</span></a></li><li id="n-upload" class="mw-list-item"><a href="/wiki/Wikipedia:File_upload_wizard" title="Add images or other media for use on Wikipedia"><span>Upload file</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> <a href="/wiki/Main_Page" class="mw-logo"> <img class="mw-logo-icon" src="/static/images/icons/wikipedia.png" alt="" aria-hidden="true" height="50" width="50"> <span class="mw-logo-container skin-invert"> <img class="mw-logo-wordmark" alt="Wikipedia" src="/static/images/mobile/copyright/wikipedia-wordmark-en.svg" style="width: 7.5em; height: 1.125em;"> <img class="mw-logo-tagline" alt="The Free Encyclopedia" src="/static/images/mobile/copyright/wikipedia-tagline-en.svg" width="117" height="13" style="width: 7.3125em; height: 0.8125em;"> </span> </a> </div> <div class="vector-header-end"> <div id="p-search" role="search" class="vector-search-box-vue vector-search-box-collapses vector-search-box-show-thumbnail vector-search-box-auto-expand-width vector-search-box"> <a href="/wiki/Special:Search" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only search-toggle" title="Search Wikipedia [f]" accesskey="f"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>Search</span> </a> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail cdx-typeahead-search--auto-expand-width"> <form action="/w/index.php" id="searchform" class="cdx-search-input cdx-search-input--has-end-button"> <div id="simpleSearch" class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="Search Wikipedia" aria-label="Search Wikipedia" autocapitalize="sentences" title="Search Wikipedia [f]" accesskey="f" id="searchInput" > <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="Special:Search"> </div> <button class="cdx-button cdx-search-input__end-button">Search</button> </form> </div> </div> </div> <nav class="vector-user-links vector-user-links-wide" aria-label="Personal tools"> <div class="vector-user-links-main"> <div id="p-vector-user-menu-preferences" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-userpage" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-dropdown" class="vector-dropdown " title="Change the appearance of the page's font size, width, and color" > <input type="checkbox" id="vector-appearance-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-appearance-dropdown" class="vector-dropdown-checkbox " aria-label="Appearance" > <label id="vector-appearance-dropdown-label" for="vector-appearance-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-appearance mw-ui-icon-wikimedia-appearance"></span> <span class="vector-dropdown-label-text">Appearance</span> </label> <div class="vector-dropdown-content"> <div id="vector-appearance-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div id="p-vector-user-menu-notifications" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-overflow" class="vector-menu mw-portlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="https://donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_en.wikipedia.org&uselang=en" class=""><span>Donate</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Special:CreateAccount&returnto=Mladen+Vranic" title="You are encouraged to create an account and log in; however, it is not mandatory" class=""><span>Create account</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Special:UserLogin&returnto=Mladen+Vranic" title="You're encouraged to log in; however, it's not mandatory. [o]" accesskey="o" class=""><span>Log in</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="Log in and more options" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="Personal tools" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">Personal tools</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="User menu" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="https://donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_en.wikipedia.org&uselang=en"><span>Donate</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:CreateAccount&returnto=Mladen+Vranic" title="You are encouraged to create an account and log in; however, it is not mandatory"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>Create account</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:UserLogin&returnto=Mladen+Vranic" title="You're encouraged to log in; however, it's not mandatory. [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>Log in</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> Pages for logged out editors <a href="/wiki/Help:Introduction" aria-label="Learn more about editing"><span>learn more</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Special:MyContributions" title="A list of edits made from this IP address [y]" accesskey="y"><span>Contributions</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Special:MyTalk" title="Discussion about edits from this IP address [n]" accesskey="n"><span>Talk</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Site"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Contents" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Contents</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">hide</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">(Top)</div> </a> </li> <li id="toc-Personal_life_and_education" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Personal_life_and_education"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Personal life and education</span> </div> </a> <ul id="toc-Personal_life_and_education-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Research" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Research"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Research</span> </div> </a> <button aria-controls="toc-Research-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Research subsection</span> </button> <ul id="toc-Research-sublist" class="vector-toc-list"> <li id="toc-Tracer_methodology" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Tracer_methodology"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.1</span> <span>Tracer methodology</span> </div> </a> <ul id="toc-Tracer_methodology-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Extrapancreatic_glucagon" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Extrapancreatic_glucagon"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2</span> <span>Extrapancreatic glucagon</span> </div> </a> <ul id="toc-Extrapancreatic_glucagon-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Glucose_metabolism" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Glucose_metabolism"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.3</span> <span>Glucose metabolism</span> </div> </a> <ul id="toc-Glucose_metabolism-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Exercise_and_stress" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Exercise_and_stress"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.4</span> <span>Exercise and stress</span> </div> </a> <ul id="toc-Exercise_and_stress-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Indirect_effect_of_insulin" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Indirect_effect_of_insulin"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.5</span> <span>Indirect effect of insulin</span> </div> </a> <ul id="toc-Indirect_effect_of_insulin-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Mechanisms_whereby_the_liver_and_muscle_are_protected_against_hypoglycemia" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Mechanisms_whereby_the_liver_and_muscle_are_protected_against_hypoglycemia"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.6</span> <span>Mechanisms whereby the liver and muscle are protected against hypoglycemia</span> </div> </a> <ul id="toc-Mechanisms_whereby_the_liver_and_muscle_are_protected_against_hypoglycemia-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Prevention_of_hypoglycemia" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Prevention_of_hypoglycemia"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.7</span> <span>Prevention of hypoglycemia</span> </div> </a> <ul id="toc-Prevention_of_hypoglycemia-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Honours_and_awards" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Honours_and_awards"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Honours and awards</span> </div> </a> <ul id="toc-Honours_and_awards-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Toggle the table of contents" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Toggle the table of contents</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Mladen Vranic</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. Available in 2 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-2" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">2 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-arz mw-list-item"><a href="https://arz.wikipedia.org/wiki/%D9%85%D9%84%D8%A7%D8%AF%D9%8A%D9%86_%D9%81%D8%B1%D8%A7%D9%86%D9%8A%D9%83" title="ملادين فرانيك – Egyptian Arabic" lang="arz" hreflang="arz" data-title="ملادين فرانيك" data-language-autonym="مصرى" data-language-local-name="Egyptian Arabic" class="interlanguage-link-target"><span>مصرى</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%92%D1%80%D0%B0%D0%BD%D0%B8%D1%87,_%D0%9C%D0%BB%D0%B0%D0%B4%D0%B5%D0%BD" title="Вранич, Младен – Russian" lang="ru" hreflang="ru" data-title="Вранич, Младен" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q16091666#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespaces"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Mladen_Vranic" title="View the content page [c]" accesskey="c"><span>Article</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Talk:Mladen_Vranic" rel="discussion" title="Discuss improvements to the content page [t]" accesskey="t"><span>Talk</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Change language variant" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">English</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Views"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Mladen_Vranic"><span>Read</span></a></li><li id="ca-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Mladen_Vranic&action=edit" title="Edit this page [e]" accesskey="e"><span>Edit</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Mladen_Vranic&action=history" title="Past revisions of this page [h]" accesskey="h"><span>View history</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Tools" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Tools</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Tools</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">hide</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="More options" > <div class="vector-menu-heading"> Actions </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Mladen_Vranic"><span>Read</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Mladen_Vranic&action=edit" title="Edit this page [e]" accesskey="e"><span>Edit</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Mladen_Vranic&action=history"><span>View history</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> General </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Special:WhatLinksHere/Mladen_Vranic" title="List of all English Wikipedia pages containing links to this page [j]" accesskey="j"><span>What links here</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Special:RecentChangesLinked/Mladen_Vranic" rel="nofollow" title="Recent changes in pages linked from this page [k]" accesskey="k"><span>Related changes</span></a></li><li id="t-upload" class="mw-list-item"><a href="/wiki/Wikipedia:File_Upload_Wizard" title="Upload files [u]" accesskey="u"><span>Upload file</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Special:SpecialPages" title="A list of all special pages [q]" accesskey="q"><span>Special pages</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Mladen_Vranic&oldid=1256330528" title="Permanent link to this revision of this page"><span>Permanent link</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Mladen_Vranic&action=info" title="More information about this page"><span>Page information</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Special:CiteThisPage&page=Mladen_Vranic&id=1256330528&wpFormIdentifier=titleform" title="Information on how to cite this page"><span>Cite this page</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Special:UrlShortener&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FMladen_Vranic"><span>Get shortened URL</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Special:QrCode&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FMladen_Vranic"><span>Download QR code</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Print/export </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Special:DownloadAsPdf&page=Mladen_Vranic&action=show-download-screen" title="Download this page as a PDF file"><span>Download as PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Mladen_Vranic&printable=yes" title="Printable version of this page [p]" accesskey="p"><span>Printable version</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> In other projects </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q16091666" title="Structured data on this page hosted by Wikidata [g]" accesskey="g"><span>Wikidata item</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Appearance"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Appearance</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">move to sidebar</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">hide</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Canadian medical researcher</div> <style data-mw-deduplicate="TemplateStyles:r1251242444">.mw-parser-output .ambox{border:1px solid #a2a9b1;border-left:10px solid #36c;background-color:#fbfbfb;box-sizing:border-box}.mw-parser-output .ambox+link+.ambox,.mw-parser-output .ambox+link+style+.ambox,.mw-parser-output .ambox+link+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+style+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+link+.ambox{margin-top:-1px}html body.mediawiki .mw-parser-output .ambox.mbox-small-left{margin:4px 1em 4px 0;overflow:hidden;width:238px;border-collapse:collapse;font-size:88%;line-height:1.25em}.mw-parser-output .ambox-speedy{border-left:10px solid #b32424;background-color:#fee7e6}.mw-parser-output .ambox-delete{border-left:10px solid #b32424}.mw-parser-output .ambox-content{border-left:10px solid #f28500}.mw-parser-output .ambox-style{border-left:10px solid #fc3}.mw-parser-output .ambox-move{border-left:10px solid #9932cc}.mw-parser-output .ambox-protection{border-left:10px solid #a2a9b1}.mw-parser-output .ambox .mbox-text{border:none;padding:0.25em 0.5em;width:100%}.mw-parser-output .ambox .mbox-image{border:none;padding:2px 0 2px 0.5em;text-align:center}.mw-parser-output .ambox .mbox-imageright{border:none;padding:2px 0.5em 2px 0;text-align:center}.mw-parser-output .ambox .mbox-empty-cell{border:none;padding:0;width:1px}.mw-parser-output .ambox .mbox-image-div{width:52px}@media(min-width:720px){.mw-parser-output .ambox{margin:0 10%}}@media print{body.ns-0 .mw-parser-output .ambox{display:none!important}}</style><style data-mw-deduplicate="TemplateStyles:r1248332772">.mw-parser-output .multiple-issues-text{width:95%;margin:0.2em 0}.mw-parser-output .multiple-issues-text>.mw-collapsible-content{margin-top:0.3em}.mw-parser-output .compact-ambox .ambox{border:none;border-collapse:collapse;background-color:transparent;margin:0 0 0 1.6em!important;padding:0!important;width:auto;display:block}body.mediawiki .mw-parser-output .compact-ambox .ambox.mbox-small-left{font-size:100%;width:auto;margin:0}.mw-parser-output .compact-ambox .ambox .mbox-text{padding:0!important;margin:0!important}.mw-parser-output .compact-ambox .ambox .mbox-text-span{display:list-item;line-height:1.5em;list-style-type:disc}body.skin-minerva .mw-parser-output .multiple-issues-text>.mw-collapsible-toggle,.mw-parser-output .compact-ambox .ambox .mbox-image,.mw-parser-output .compact-ambox .ambox .mbox-imageright,.mw-parser-output .compact-ambox .ambox .mbox-empty-cell,.mw-parser-output .compact-ambox .hide-when-compact{display:none}</style><table class="box-Multiple_issues plainlinks metadata ambox ambox-content ambox-multiple_issues compact-ambox" role="presentation"><tbody><tr><td class="mbox-image"><div class="mbox-image-div"><span typeof="mw:File"><span><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/b/b4/Ambox_important.svg/40px-Ambox_important.svg.png" decoding="async" width="40" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/b/b4/Ambox_important.svg/60px-Ambox_important.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/b/b4/Ambox_important.svg/80px-Ambox_important.svg.png 2x" data-file-width="40" data-file-height="40" /></span></span></div></td><td class="mbox-text"><div class="mbox-text-span"><div class="multiple-issues-text mw-collapsible"><b>This article has multiple issues.</b> Please help <b><a href="/wiki/Special:EditPage/Mladen_Vranic" title="Special:EditPage/Mladen Vranic">improve it</a></b> or discuss these issues on the <b><a href="/wiki/Talk:Mladen_Vranic" title="Talk:Mladen Vranic">talk page</a></b>. <small><i>(<a href="/wiki/Help:Maintenance_template_removal" title="Help:Maintenance template removal">Learn how and when to remove these messages</a>)</i></small> <div class="mw-collapsible-content"> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1251242444"><table class="box-Autobiography plainlinks metadata ambox ambox-content ambox-autobiography" role="presentation"><tbody><tr><td class="mbox-image"><div class="mbox-image-div"><span typeof="mw:File"><span><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/b/b4/Ambox_important.svg/40px-Ambox_important.svg.png" decoding="async" width="40" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/b/b4/Ambox_important.svg/60px-Ambox_important.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/b/b4/Ambox_important.svg/80px-Ambox_important.svg.png 2x" data-file-width="40" data-file-height="40" /></span></span></div></td><td class="mbox-text"><div class="mbox-text-span">This article <b>is an <a href="/wiki/Wikipedia:Autobiography" title="Wikipedia:Autobiography">autobiography</a> or has been extensively edited by the subject or by someone connected to the subject</b>.<span class="hide-when-compact"> It may need editing to conform to Wikipedia's <a href="/wiki/Wikipedia:Neutral_point_of_view" title="Wikipedia:Neutral point of view">neutral point of view</a> policy. There may be relevant discussion on the <a href="/wiki/Talk:Mladen_Vranic" title="Talk:Mladen Vranic">talk page</a>.</span> <span class="date-container"><i>(<span class="date">June 2017</span>)</i></span><span class="hide-when-compact"><i> (<small><a href="/wiki/Help:Maintenance_template_removal" title="Help:Maintenance template removal">Learn how and when to remove this message</a></small>)</i></span></div></td></tr></tbody></table> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1251242444"><table class="box-Primary_sources plainlinks metadata ambox ambox-content ambox-Primary_sources" role="presentation"><tbody><tr><td class="mbox-image"><div class="mbox-image-div"><span typeof="mw:File"><a href="/wiki/File:Question_book-new.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/en/thumb/9/99/Question_book-new.svg/50px-Question_book-new.svg.png" decoding="async" width="50" height="39" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/9/99/Question_book-new.svg/75px-Question_book-new.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/9/99/Question_book-new.svg/100px-Question_book-new.svg.png 2x" data-file-width="512" data-file-height="399" /></a></span></div></td><td class="mbox-text"><div class="mbox-text-span">This article <b>relies excessively on <a href="/wiki/Wikipedia:Verifiability" title="Wikipedia:Verifiability">references</a> to <a href="/wiki/Wikipedia:No_original_research#Primary,_secondary_and_tertiary_sources" title="Wikipedia:No original research">primary sources</a></b>.<span class="hide-when-compact"> Please improve this article by adding <a href="/wiki/Wikipedia:No_original_research#Primary,_secondary_and_tertiary_sources" title="Wikipedia:No original research">secondary or tertiary sources</a>. <br /><small><span class="plainlinks"><i>Find sources:</i> <a rel="nofollow" class="external text" href="https://www.google.com/search?as_eq=wikipedia&q=%22Mladen+Vranic%22">"Mladen Vranic"</a> – <a rel="nofollow" class="external text" href="https://www.google.com/search?tbm=nws&q=%22Mladen+Vranic%22+-wikipedia&tbs=ar:1">news</a> <b>·</b> <a rel="nofollow" class="external text" href="https://www.google.com/search?&q=%22Mladen+Vranic%22&tbs=bkt:s&tbm=bks">newspapers</a> <b>·</b> <a rel="nofollow" class="external text" href="https://www.google.com/search?tbs=bks:1&q=%22Mladen+Vranic%22+-wikipedia">books</a> <b>·</b> <a rel="nofollow" class="external text" href="https://scholar.google.com/scholar?q=%22Mladen+Vranic%22">scholar</a> <b>·</b> <a rel="nofollow" class="external text" href="https://www.jstor.org/action/doBasicSearch?Query=%22Mladen+Vranic%22&acc=on&wc=on">JSTOR</a></span></small></span> <span class="date-container"><i>(<span class="date">June 2017</span>)</i></span><span class="hide-when-compact"><i> (<small><a href="/wiki/Help:Maintenance_template_removal" title="Help:Maintenance template removal">Learn how and when to remove this message</a></small>)</i></span></div></td></tr></tbody></table> </div> </div><span class="hide-when-compact"><i> (<small><a href="/wiki/Help:Maintenance_template_removal" title="Help:Maintenance template removal">Learn how and when to remove this message</a></small>)</i></span></div></td></tr></tbody></table> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox biography vcard"><tbody><tr><th colspan="2" class="infobox-above" style="font-size:125%;"><div class="fn">Mladen Vranić</div></th></tr><tr><th scope="row" class="infobox-label">Born</th><td class="infobox-data"><span style="display:none">(<span class="bday">1930-04-03</span>)</span>3 April 1930<br /><div style="display:inline" class="birthplace"><a href="/wiki/Zagreb" title="Zagreb">Zagreb</a>, <a href="/wiki/Croatia" title="Croatia">Croatia</a></div></td></tr><tr><th scope="row" class="infobox-label">Died</th><td class="infobox-data">18 June 2019<span style="display:none">(2019-06-18)</span> (aged 89)</td></tr><tr><th scope="row" class="infobox-label">Nationality</th><td class="infobox-data category"><a href="/wiki/Croats" title="Croats">Croat</a> <a href="/wiki/Canadians" title="Canadians">Canadian</a></td></tr><tr><th scope="row" class="infobox-label">Alma mater</th><td class="infobox-data"><a href="/wiki/University_of_Zagreb" title="University of Zagreb">University of Zagreb</a></td></tr></tbody></table> <p><b>Mladen Vranic</b>, MD, DSc, <a href="/wiki/Order_of_Canada" title="Order of Canada">O.C.</a>, <a href="/wiki/Order_of_Ontario" title="Order of Ontario">O.Ont</a>, <a href="/wiki/Fellow_of_the_Royal_Society_of_Canada" title="Fellow of the Royal Society of Canada">FRSC</a>, <a href="/wiki/Royal_College_of_Physicians_and_Surgeons_of_Canada" title="Royal College of Physicians and Surgeons of Canada">FRCP(C)</a>, <a href="/wiki/Canadian_Academy_of_Health_Sciences" title="Canadian Academy of Health Sciences">FCAHS</a>, Canadian Medical Hall of Fame[CMHF] April 3, 1930 – June 18, 2019,<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> was a <a href="/wiki/Croatia" title="Croatia">Croatian</a>-born <a href="/wiki/Diabetes" title="Diabetes">diabetes</a> researcher, best known for his work in tracer methodology, exercise and stress in diabetes, the metabolic effects of hormonal interactions, <a href="/wiki/Glucagon" title="Glucagon">glucagon</a> physiology, extrapancreatic glucagon, the role of the direct and indirect metabolic effects of <a href="/wiki/Insulin" title="Insulin">insulin</a> and the prevention of <a href="/wiki/Hypoglycemia" title="Hypoglycemia">hypoglycemia</a>. Vranic was recognized by a number of national and international awards for his research contributions, mentoring and administration including the Orders of Canada (Officer) and Ontario. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Personal_life_and_education">Personal life and education</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=1" title="Edit section: Personal life and education"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Mladen Vranic (<a href="/wiki/Croatian_language" title="Croatian language">Croatian</a>: <i lang="hr">Vranić</i>) was born in 1930 to <a href="/wiki/Vladimir_Vrani%C4%87" title="Vladimir Vranić">Vladimir Vranić</a> and Ana Vranić in <a href="/wiki/Zagreb" title="Zagreb">Zagreb</a>, Croatia. His Jewish father converted to Christianity in 1920, and his mother converted upon marriage, but they were both non-observant. His father was a professor at the Faculty of Economics, Engineering, and Sciences, and Dean at the School of Economics and Engineering at the <a href="/wiki/University_of_Zagreb" title="University of Zagreb">University of Zagreb</a>. His mother ran a beauty salon in Zagreb. </p><p>Vranic's immediate family escaped from the Holocaust due to the Italians' humane treatment of Jews. After the collapse of Italy, his family escaped with a partisan boat to <a href="/wiki/Vis_(island)" title="Vis (island)">Vis</a>, an island governed by Allied Forces and Croatian partisans, and then on a British military ship to Taranto, Italy, which was already under supervision by the Allied Forces. During the last year of the war, his father joined the partisans.<sup id="cite_ref-First_2-0" class="reference"><a href="#cite_note-First-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>After the war, his family returned to Zagreb where Vranic completed high school, medical school (1955) and received a D.Sc. in physiology at the University of Zagreb in 1962. Vranic was invited to be the last post-doctoral fellow of <a href="/wiki/Charles_Alexander_Best" title="Charles Alexander Best">Charles Best</a>, a co-discoverer of <a href="/wiki/Insulin" title="Insulin">insulin</a>.<sup id="cite_ref-First_2-1" class="reference"><a href="#cite_note-First-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> He was promoted to assistant professor in 1965, associate professor in 1968 and full professor in 1972 at the University of Toronto Department of Physiology. Vranic was chair of the <a href="/wiki/University_of_Toronto" title="University of Toronto">Department of Physiology</a> from 1991 to 1995. In 1978 he was cross-appointed to professor in the Faculty of Medicine. In 1976-1977 he was an invited professor at the <a href="/wiki/University_of_Geneva" title="University of Geneva">University of Geneva</a> during a sabbatical leave and a visiting research fellow of <a href="/wiki/Merton_College" class="mw-redirect" title="Merton College">Merton College</a> at the <a href="/wiki/University_of_Oxford" title="University of Oxford">University of Oxford</a>. From 1973 to 1978 he was appointed a member of the Institute of Biomedical Electronics and Engineering at the University of Toronto. </p><p>He was an adjunct professor at the Karolinska Institute, Stockholm and at the <a href="/wiki/University_of_Zagreb" title="University of Zagreb">University of Zagreb</a>, <a href="/wiki/Croatia" title="Croatia">Croatia</a>. Vranic is also a member of the division of endocrinology and metabolism at the department of medicine and a fellow at the Senior Scholar's College at the University of Toronto.<sup id="cite_ref-Second_3-0" class="reference"><a href="#cite_note-Second-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p><p>His first wife, Magda Vranic, was an assistant professor in rehabilitation medicine at the University of Toronto. She died of breast cancer at the age of 50. Together, they had two daughters (Iva and Maja (deceased). He married Linda Margaret Swallow in 1983. Together they had two daughters (Claire and Anne). </p><p>Vranic died on June 18, 2019, in Toronto, Canada, of congestive heart failure.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Research">Research</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=2" title="Edit section: Research"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Vranic's research accomplishments reflect the supervision of a large number of graduate students and post-doctoral fellows, and wide collaboration with basic and clinical researchers who were crucial for interaction between basic science, molecular and cell biology, and clinical research. He has 214 peer-reviewed publications and is recognized for his research contributions in the following areas: </p> <div class="mw-heading mw-heading3"><h3 id="Tracer_methodology">Tracer methodology</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=3" title="Edit section: Tracer methodology"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The treatment of <a href="/wiki/Diabetes_mellitus" class="mw-redirect" title="Diabetes mellitus">diabetes</a> concentrates on the liver and/or the periphery. Vranic quantified hormonal and metabolic interactions involved in the physiology and <a href="/wiki/Pathogenesis" title="Pathogenesis">pathogenesis</a> of diabetes by developing tracer methods to separate the effects of diabetes on both. A large amount of his research accomplishments are due to measurement of non-steady state <a href="/wiki/Glucose" title="Glucose">glucose</a> kinetics. He collaborated in the first clinical tracer studies on insulin resistance, <a href="/wiki/Hypertriglyceridemia" title="Hypertriglyceridemia">hypertriglyceridemia</a>, and the <a href="/wiki/Cori_cycle" title="Cori cycle">Cori cycle</a>.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Extrapancreatic_glucagon">Extrapancreatic glucagon</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=4" title="Edit section: Extrapancreatic glucagon"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Diabetes reflects insulin deficiency and glucagon abundance. Vranic discovered extrapancreatic glucagon in dogs, which changed the prevailing dogma and permitted precise exploration of the roles of insulin and glucagon in physiology and diabetes, and provided conclusive evidence about the role of glucagon in diabetes. Before his research, glucagon was considered to have effects on many organs, but he was the first to measure the physiological role of glucagon, based on the effect of glucagon on glucose turnover. In contrast to prevailing beliefs, he was the first to indicate that glucagon only acts on the liver. He was also the first to quantify the physiological secretion of insulin.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Glucose_metabolism">Glucose metabolism</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=5" title="Edit section: Glucose metabolism"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Vranic was the first to establish the critical role of glucagon-insulin interaction and the control of glucose metabolism during moderate exercise and of <a href="/wiki/Catecholamine" title="Catecholamine">catecholamines</a> during strenuous exercise. He quantified the deficiencies in the release and effects of these hormones in diabetes. He also revealed how acute and chronic <a href="/wiki/Hyperglycemia" title="Hyperglycemia">hyperglycemia</a> affects the expression of GLUT2 gene and protein in diabetes.<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Giacca,_A.,_Fisher,_S.,_Gupta,_R.,_Shi,_Z.Q.,_Lickley,_L._and_Vranic,_M._1992_1769–1777_15-0" class="reference"><a href="#cite_note-Giacca,_A.,_Fisher,_S.,_Gupta,_R.,_Shi,_Z.Q.,_Lickley,_L._and_Vranic,_M._1992_1769–1777-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Exercise_and_stress">Exercise and stress</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=6" title="Edit section: Exercise and stress"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Vranic pioneered new concepts of the role of exercise in diabetes, leading to precise methods of controlling insulin, allowing type 1 diabetics to participate in the Olympics and clinicians to recommend exercise and healthy eating habits to prevent type 2 diabetes. He outlined molecular and physiological mechanisms whereby exercise training and adaptation to repetitive neurogenic stress can prevent diabetes in <a href="/wiki/Laboratory_rat" title="Laboratory rat">Zucker Diabetic Fatty (ZDF) rats</a>.<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-24" class="reference"><a href="#cite_note-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-25" class="reference"><a href="#cite_note-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Indirect_effect_of_insulin">Indirect effect of insulin</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=7" title="Edit section: Indirect effect of insulin"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Vranic and others established that the indirect effect of insulin plays an important role in the regulation of glucose production in dogs. They confirmed this effect in humans and its role in <a href="/wiki/Diabetes_mellitus_type_2" class="mw-redirect" title="Diabetes mellitus type 2">type 2 diabetes</a>.<sup id="cite_ref-Giacca,_A.,_Fisher,_S.,_Gupta,_R.,_Shi,_Z.Q.,_Lickley,_L._and_Vranic,_M._1992_1769–1777_15-1" class="reference"><a href="#cite_note-Giacca,_A.,_Fisher,_S.,_Gupta,_R.,_Shi,_Z.Q.,_Lickley,_L._and_Vranic,_M._1992_1769–1777-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-26" class="reference"><a href="#cite_note-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-27" class="reference"><a href="#cite_note-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-28" class="reference"><a href="#cite_note-28"><span class="cite-bracket">[</span>28<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-29" class="reference"><a href="#cite_note-29"><span class="cite-bracket">[</span>29<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Mechanisms_whereby_the_liver_and_muscle_are_protected_against_hypoglycemia">Mechanisms whereby the liver and muscle are protected against hypoglycemia</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=8" title="Edit section: Mechanisms whereby the liver and muscle are protected against hypoglycemia"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Vranic showed that because the muscle and the liver are protected against changes in glucose levels, these organs do not have diabetic complications.<sup id="cite_ref-30" class="reference"><a href="#cite_note-30"><span class="cite-bracket">[</span>30<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-31" class="reference"><a href="#cite_note-31"><span class="cite-bracket">[</span>31<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-32" class="reference"><a href="#cite_note-32"><span class="cite-bracket">[</span>32<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-33" class="reference"><a href="#cite_note-33"><span class="cite-bracket">[</span>33<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-34" class="reference"><a href="#cite_note-34"><span class="cite-bracket">[</span>34<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-35" class="reference"><a href="#cite_note-35"><span class="cite-bracket">[</span>35<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Prevention_of_hypoglycemia">Prevention of hypoglycemia</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=9" title="Edit section: Prevention of hypoglycemia"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Vranic described the molecular mechanisms responsible for increased HPA axis in diabetes and for the diminished responses of HPA axis, catecholamines and glucagon to hypoglycemia. He proposed a new approach to decrease the threat of hypoglycemia by blocking the effect of <a href="/wiki/Somatostatin" title="Somatostatin">somatostatin</a>.<sup id="cite_ref-36" class="reference"><a href="#cite_note-36"><span class="cite-bracket">[</span>36<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-37" class="reference"><a href="#cite_note-37"><span class="cite-bracket">[</span>37<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-38" class="reference"><a href="#cite_note-38"><span class="cite-bracket">[</span>38<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-39" class="reference"><a href="#cite_note-39"><span class="cite-bracket">[</span>39<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-40" class="reference"><a href="#cite_note-40"><span class="cite-bracket">[</span>40<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-41" class="reference"><a href="#cite_note-41"><span class="cite-bracket">[</span>41<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-42" class="reference"><a href="#cite_note-42"><span class="cite-bracket">[</span>42<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-43" class="reference"><a href="#cite_note-43"><span class="cite-bracket">[</span>43<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-44" class="reference"><a href="#cite_note-44"><span class="cite-bracket">[</span>44<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-45" class="reference"><a href="#cite_note-45"><span class="cite-bracket">[</span>45<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-46" class="reference"><a href="#cite_note-46"><span class="cite-bracket">[</span>46<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-47" class="reference"><a href="#cite_note-47"><span class="cite-bracket">[</span>47<span class="cite-bracket">]</span></a></sup> Vranic's research accomplishments and his main collaborators are summarized in a career retrospective entitled: "Odyssey between Scylla and Charybdis through storms of carbohydrate metabolism and diabetes: a career retrospective. Am J Physiol Endocrinol Metab 299: E849–E867, 2010".<sup id="cite_ref-48" class="reference"><a href="#cite_note-48"><span class="cite-bracket">[</span>48<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Honours_and_awards">Honours and awards</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=10" title="Edit section: Honours and awards"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The Symposium to Honour Mladen Vranic for a Lifetime of Scientific Achievements and Mentoring, Toronto, Ontario, Canada (2010); he is a Laureate of the <a href="/wiki/Canadian_Medical_Hall_of_Fame" title="Canadian Medical Hall of Fame">Canadian Medical Hall of Fame</a> (2009); the Canadian Diabetes Association Inaugural Life-Time Achievement Award for leadership in diabetes research and contribution to the Canadian diabetes community (2007); the honorary keynote speaker on Endocrinology and Diabetes; he is a member of The Society of Chinese Bioscientists of North America (2006); the Albert Renold Award from the American Diabetes Association for a distinguished career in the training of diabetes research scientists and facilitation of research (the only Canadian to receive this award) (2005); he is a Poll Visiting Scholar, University of Washington, Seattle, Washington (1995); the Novo Nordisk Lecture, Karolinska Institute, Stockholm (1995); the Solomon A. Berson Distinguished Lectureship of American Physiological Society - Endocrinology and Metabolism Section, FASEB, Atlanta (the first Canadian to receive this award) (1995); recognition for outstanding contributions to the Juvenile Diabetes Foundation, Canada (1994); the Mizuno Inaugural Lectureship and Award, Fourth International Symposium on Exercise and Diabetes - Osaka University, Japan (1992); the Banting Medal and Lectureship for Distinguished Scientific Achievement (American Diabetes Association) (1991); the R. Kroc Lectureship, University of Southern California School of Medicine, Los Angeles (1991); the Peter J. Laurie Memorial Lecture of Juvenile Diabetes Foundation Canada, Toronto (1991); the JDFI Mary Kugel Award (1989); the Inaugural Banting and Best Memorial Lecture and the Canadian Diabetes Association Award (1985); he is a Canada Council Killam Scholar (1988, 1989).<sup id="cite_ref-Second_3-1" class="reference"><a href="#cite_note-Second-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Mladen_Vranic&action=edit&section=11" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.cdnmedhall.org/inductees/mladenvranic">"Mladen Vranic MD DSc"</a>. <i>Canadian Medical Hall of Fame</i><span class="reference-accessdate">. Retrieved <span class="nowrap">January 1,</span> 2020</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Canadian+Medical+Hall+of+Fame&rft.atitle=Mladen+Vranic+MD+DSc&rft_id=http%3A%2F%2Fwww.cdnmedhall.org%2Finductees%2Fmladenvranic&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-First-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-First_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-First_2-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJiménez2009" class="citation news cs1">Jiménez, Marina (Jun 4, 2009). <a rel="nofollow" class="external text" href="https://www.theglobeandmail.com/life/health-and-fitness/i-dont-give-up-easily/article4212697/">"<span class="cs1-kern-left"></span>'I don't give up easily'<span class="cs1-kern-right"></span>"</a>. <i>The Globe and Mail</i>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20160304094042/http://www.theglobeandmail.com/life/health-and-fitness/i-dont-give-up-easily/article4212697/">Archived</a> from the original on 4 March 2016<span class="reference-accessdate">. Retrieved <span class="nowrap">21 January</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Globe+and+Mail&rft.atitle=%27I+don%27t+give+up+easily%27&rft.date=2009-06-04&rft.aulast=Jim%C3%A9nez&rft.aufirst=Marina&rft_id=https%3A%2F%2Fwww.theglobeandmail.com%2Flife%2Fhealth-and-fitness%2Fi-dont-give-up-easily%2Farticle4212697%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-Second-3"><span class="mw-cite-backlink">^ <a href="#cite_ref-Second_3-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Second_3-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDepartment_of_Physiology,_University_of_Toronto" class="citation web cs1">Department of Physiology, University of Toronto. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20140304050538/http://www.physiology.utoronto.ca/res/list/vranic.htm">"Mladen Vranic"</a>. Archived from <a rel="nofollow" class="external text" href="http://www.physiology.utoronto.ca/res/list/vranic.htm">the original</a> on March 4, 2014<span class="reference-accessdate">. Retrieved <span class="nowrap">January 26,</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Mladen+Vranic&rft.au=Department+of+Physiology%2C+University+of+Toronto&rft_id=http%3A%2F%2Fwww.physiology.utoronto.ca%2Fres%2Flist%2Fvranic.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text">The Globe and Mail, July 18, 2019</span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRadziuk,_J.,_Norwich,_K.H._and_Vranic,_M.1978" class="citation journal cs1">Radziuk, J., Norwich, K.H. and Vranic, M. (1978). "Experimental validation of measurements of glucose turnover in nonsteady state". <i>American Journal of Physiology</i>. <b>234</b> (1): E84–E93. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpendo.1978.234.1.E84">10.1152/ajpendo.1978.234.1.E84</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/623255">623255</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:12698982">12698982</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Physiology&rft.atitle=Experimental+validation+of+measurements+of+glucose+turnover+in+nonsteady+state&rft.volume=234&rft.issue=1&rft.pages=E84-E93&rft.date=1978&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A12698982%23id-name%3DS2CID&rft_id=info%3Apmid%2F623255&rft_id=info%3Adoi%2F10.1152%2Fajpendo.1978.234.1.E84&rft.au=Radziuk%2C+J.%2C+Norwich%2C+K.H.+and+Vranic%2C+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFinegood,_D.T.,_Bergman,_R.N._and_Vranic,_M.1987" class="citation journal cs1">Finegood, D.T., Bergman, R.N. and Vranic, M. (1987). "Estimation of endogenous glucose production during hyperinsulinemic euglycemic glucose clamps: Comparison of unlabeled and labeled exogenous glucose infusates". <i>Diabetes</i>. <b>36</b> (8): 914–924. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.36.8.914">10.2337/diabetes.36.8.914</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3297886">3297886</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Estimation+of+endogenous+glucose+production+during+hyperinsulinemic+euglycemic+glucose+clamps%3A+Comparison+of+unlabeled+and+labeled+exogenous+glucose+infusates&rft.volume=36&rft.issue=8&rft.pages=914-924&rft.date=1987&rft_id=info%3Adoi%2F10.2337%2Fdiabetes.36.8.914&rft_id=info%3Apmid%2F3297886&rft.au=Finegood%2C+D.T.%2C+Bergman%2C+R.N.+and+Vranic%2C+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFVranic,_M.,_Pek,_S._and_Kawamori,_R.1975" class="citation journal cs1">Vranic, M., Pek, S. and Kawamori, R. (1975). "Increased "glucagon immunoreactivity" in plasma of totally depancreatized dogs". <i>Diabetes</i>. <b>23</b> (11): 905–912. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiab.23.11.905">10.2337/diab.23.11.905</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/4430418">4430418</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:38025716">38025716</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Increased+%22glucagon+immunoreactivity%22+in+plasma+of+totally+depancreatized+dogs&rft.volume=23&rft.issue=11&rft.pages=905-912&rft.date=1975&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A38025716%23id-name%3DS2CID&rft_id=info%3Apmid%2F4430418&rft_id=info%3Adoi%2F10.2337%2Fdiab.23.11.905&rft.au=Vranic%2C+M.%2C+Pek%2C+S.+and+Kawamori%2C+R.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFVranic,_M.,_Kawamori,_R.,_Pek,_S.,_Kovacevic,_N._and_Wrenshall,_G.A.1975" class="citation journal cs1">Vranic, M., Kawamori, R., Pek, S., Kovacevic, N. and Wrenshall, G.A. (1975). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC436648">"The essentiality of insulin and the role of glucagon in regulating glucose turnover during strenuous exercise"</a>. <i>Journal of Clinical Investigation</i>. <b>57</b> (2): 245–255. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1172%2Fjci108275">10.1172/jci108275</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC436648">436648</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1254723">1254723</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Investigation&rft.atitle=The+essentiality+of+insulin+and+the+role+of+glucagon+in+regulating+glucose+turnover+during+strenuous+exercise&rft.volume=57&rft.issue=2&rft.pages=245-255&rft.date=1975&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC436648%23id-name%3DPMC&rft_id=info%3Apmid%2F1254723&rft_id=info%3Adoi%2F10.1172%2Fjci108275&rft.au=Vranic%2C+M.%2C+Kawamori%2C+R.%2C+Pek%2C+S.%2C+Kovacevic%2C+N.+and+Wrenshall%2C+G.A.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC436648&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMuller,_W.A.,_Girardier,_L.,_Seydoux,_J.,_Berger,_M.,_Renold,_A.E._and_Vranic,_M.1978" class="citation journal cs1">Muller, W.A., Girardier, L., Seydoux, J., Berger, M., Renold, A.E. and Vranic, M. (1978). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC371745">"Extrapancreatic glucagon and glucagon-like immunoreactivity in depancreatized dogs: a quantitative assessment of secretion rates and anatomical delineation of sources"</a>. <i>Journal of Clinical Investigation</i>. <b>62</b> (1): 124–132. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1172%2Fjci109096">10.1172/jci109096</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC371745">371745</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/659625">659625</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Investigation&rft.atitle=Extrapancreatic+glucagon+and+glucagon-like+immunoreactivity+in+depancreatized+dogs%3A+a+quantitative+assessment+of+secretion+rates+and+anatomical+delineation+of+sources&rft.volume=62&rft.issue=1&rft.pages=124-132&rft.date=1978&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC371745%23id-name%3DPMC&rft_id=info%3Apmid%2F659625&rft_id=info%3Adoi%2F10.1172%2Fjci109096&rft.au=Muller%2C+W.A.%2C+Girardier%2C+L.%2C+Seydoux%2C+J.%2C+Berger%2C+M.%2C+Renold%2C+A.E.+and+Vranic%2C+M.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC371745&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-10">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDoi,_K.,_Prentki,_M.,_Yip,_C.,_Muller,_W.,_Jeanrenaud,_B._and_Vranic,_M.1979" class="citation journal cs1">Doi, K., Prentki, M., Yip, C., Muller, W., Jeanrenaud, B. and Vranic, M. (1979). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC371982">"Identical biological effects of pancreatic glucagon and a purified moiety of canine gastric glucagon. J"</a>. <i>Journal of Clinical Investigation</i>. <b>63</b> (3): 525–531. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1172%2Fjci109331">10.1172/jci109331</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC371982">371982</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/429572">429572</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Investigation&rft.atitle=Identical+biological+effects+of+pancreatic+glucagon+and+a+purified+moiety+of+canine+gastric+glucagon.+J&rft.volume=63&rft.issue=3&rft.pages=525-531&rft.date=1979&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC371982%23id-name%3DPMC&rft_id=info%3Apmid%2F429572&rft_id=info%3Adoi%2F10.1172%2Fjci109331&rft.au=Doi%2C+K.%2C+Prentki%2C+M.%2C+Yip%2C+C.%2C+Muller%2C+W.%2C+Jeanrenaud%2C+B.+and+Vranic%2C+M.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC371982&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-11">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFVranic,_M.,_Morita,_S._and_Steiner,_G.1980" class="citation journal cs1">Vranic, M., Morita, S. and Steiner, G. (1980). "Insulin resistance in obesity analyzed by the response of glucose kinetics to glucagon infusion". <i>Diabetes</i>. <b>29</b> (3): 169–176. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.29.3.169">10.2337/diabetes.29.3.169</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/6991320">6991320</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Insulin+resistance+in+obesity+analyzed+by+the+response+of+glucose+kinetics+to+glucagon+infusion&rft.volume=29&rft.issue=3&rft.pages=169-176&rft.date=1980&rft_id=info%3Adoi%2F10.2337%2Fdiabetes.29.3.169&rft_id=info%3Apmid%2F6991320&rft.au=Vranic%2C+M.%2C+Morita%2C+S.+and+Steiner%2C+G.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-12"><span class="mw-cite-backlink"><b><a href="#cite_ref-12">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWajngot,_A.,_Roovete,_A.,_Vranic,_M.,_Luft,_R._and_Efendic,_S.1982" class="citation journal cs1">Wajngot, A., Roovete, A., Vranic, M., Luft, R. and Efendic, S. (1982). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC346686">"Insulin resistance and decreased insulin response to glucose in lean Type II diabetics"</a>. <i>Proceedings of the National Academy of Sciences</i>. <b>79</b> (14): 4432–4436. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1982PNAS...79.4432W">1982PNAS...79.4432W</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.79.14.4432">10.1073/pnas.79.14.4432</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC346686">346686</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/6750603">6750603</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences&rft.atitle=Insulin+resistance+and+decreased+insulin+response+to+glucose+in+lean+Type+II+diabetics&rft.volume=79&rft.issue=14&rft.pages=4432-4436&rft.date=1982&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC346686%23id-name%3DPMC&rft_id=info%3Apmid%2F6750603&rft_id=info%3Adoi%2F10.1073%2Fpnas.79.14.4432&rft_id=info%3Abibcode%2F1982PNAS...79.4432W&rft.au=Wajngot%2C+A.%2C+Roovete%2C+A.%2C+Vranic%2C+M.%2C+Luft%2C+R.+and+Efendic%2C+S.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC346686&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-13"><span class="mw-cite-backlink"><b><a href="#cite_ref-13">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKemmer,_F.W.,_Sirek,_A.,_Sirek,_O.V.,_Perez,_G._and_Vranic,_M.1983" class="citation journal cs1">Kemmer, F.W., Sirek, A., Sirek, O.V., Perez, G. and Vranic, M. (1983). "Glucoregulatory mechanisms following hypophysectomy in diabetic dogs with residual insulin secretion". <i>Diabetes</i>. <b>32</b> (1): 26–34. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiab.32.1.26">10.2337/diab.32.1.26</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/6129169">6129169</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:39871361">39871361</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Glucoregulatory+mechanisms+following+hypophysectomy+in+diabetic+dogs+with+residual+insulin+secretion&rft.volume=32&rft.issue=1&rft.pages=26-34&rft.date=1983&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A39871361%23id-name%3DS2CID&rft_id=info%3Apmid%2F6129169&rft_id=info%3Adoi%2F10.2337%2Fdiab.32.1.26&rft.au=Kemmer%2C+F.W.%2C+Sirek%2C+A.%2C+Sirek%2C+O.V.%2C+Perez%2C+G.+and+Vranic%2C+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-14"><span class="mw-cite-backlink"><b><a href="#cite_ref-14">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWajngot,_A.,_Giacca,_A.,_Grill,_V.,_Vranic,_M._and_Efendic,_S.1992" class="citation journal cs1">Wajngot, A., Giacca, A., Grill, V., Vranic, M. and Efendic, S. (1992). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC402133">"The diabetogenic effects of glucocorticoids are more pronounced in low than in high insulin responders"</a>. <i>Proceedings of the National Academy of Sciences</i>. <b>89</b> (13): 6035–6039. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1992PNAS...89.6035W">1992PNAS...89.6035W</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.89.13.6035">10.1073/pnas.89.13.6035</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC402133">402133</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1631088">1631088</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences&rft.atitle=The+diabetogenic+effects+of+glucocorticoids+are+more+pronounced+in+low+than+in+high+insulin+responders&rft.volume=89&rft.issue=13&rft.pages=6035-6039&rft.date=1992&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC402133%23id-name%3DPMC&rft_id=info%3Apmid%2F1631088&rft_id=info%3Adoi%2F10.1073%2Fpnas.89.13.6035&rft_id=info%3Abibcode%2F1992PNAS...89.6035W&rft.au=Wajngot%2C+A.%2C+Giacca%2C+A.%2C+Grill%2C+V.%2C+Vranic%2C+M.+and+Efendic%2C+S.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC402133&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-Giacca,_A.,_Fisher,_S.,_Gupta,_R.,_Shi,_Z.Q.,_Lickley,_L._and_Vranic,_M._1992_1769–1777-15"><span class="mw-cite-backlink">^ <a href="#cite_ref-Giacca,_A.,_Fisher,_S.,_Gupta,_R.,_Shi,_Z.Q.,_Lickley,_L._and_Vranic,_M._1992_1769–1777_15-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Giacca,_A.,_Fisher,_S.,_Gupta,_R.,_Shi,_Z.Q.,_Lickley,_L._and_Vranic,_M._1992_1769–1777_15-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGiacca,_A.,_Fisher,_S.,_Gupta,_R.,_Shi,_Z.Q.,_Lickley,_L._and_Vranic,_M.1992" class="citation journal cs1">Giacca, A., Fisher, S., Gupta, R., Shi, Z.Q., Lickley, L. and Vranic, M. (1992). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC443235">"Importance of peripheral mechanisms of insulin action for the regulation of hepatic glucose production in diabetes"</a>. <i>Journal of Clinical Investigation</i>. <b>90</b> (5): 1769–1777. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1172%2FJCI116051">10.1172/JCI116051</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC443235">443235</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1430203">1430203</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Investigation&rft.atitle=Importance+of+peripheral+mechanisms+of+insulin+action+for+the+regulation+of+hepatic+glucose+production+in+diabetes&rft.volume=90&rft.issue=5&rft.pages=1769-1777&rft.date=1992&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC443235%23id-name%3DPMC&rft_id=info%3Apmid%2F1430203&rft_id=info%3Adoi%2F10.1172%2FJCI116051&rft.au=Giacca%2C+A.%2C+Fisher%2C+S.%2C+Gupta%2C+R.%2C+Shi%2C+Z.Q.%2C+Lickley%2C+L.+and+Vranic%2C+M.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC443235&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-16">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKawamori,_R.Vranic,_M.1977" class="citation journal cs1">Kawamori, R.; Vranic, M. (1977). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC333364">"Mechanisms of exercise-induced hypoglycemia in depancreatized dogs maintained on long acting insulin"</a>. <i>Journal of Clinical Investigation</i>. <b>59</b> (2): 331–337. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1172%2Fjci108645">10.1172/jci108645</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC333364">333364</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/833280">833280</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Investigation&rft.atitle=Mechanisms+of+exercise-induced+hypoglycemia+in+depancreatized+dogs+maintained+on+long+acting+insulin&rft.volume=59&rft.issue=2&rft.pages=331-337&rft.date=1977&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC333364%23id-name%3DPMC&rft_id=info%3Apmid%2F833280&rft_id=info%3Adoi%2F10.1172%2Fjci108645&rft.au=Kawamori%2C+R.&rft.au=Vranic%2C+M.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC333364&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-17"><span class="mw-cite-backlink"><b><a href="#cite_ref-17">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFIssekutz,_B.Vranic,_M.1980" class="citation journal cs1">Issekutz, B.; Vranic, M. (1980). "Role of glucagon in the regulation of glucose production in exercising dogs". <i>American Journal of Physiology</i>. <b>238</b> (1): E13–E20. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpendo.1980.238.1.E13">10.1152/ajpendo.1980.238.1.E13</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/6986792">6986792</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Physiology&rft.atitle=Role+of+glucagon+in+the+regulation+of+glucose+production+in+exercising+dogs&rft.volume=238&rft.issue=1&rft.pages=E13-E20&rft.date=1980&rft_id=info%3Adoi%2F10.1152%2Fajpendo.1980.238.1.E13&rft_id=info%3Apmid%2F6986792&rft.au=Issekutz%2C+B.&rft.au=Vranic%2C+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-18"><span class="mw-cite-backlink"><b><a href="#cite_ref-18">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWasserman,_D.H.,_Lickley,_H.L.A._and_Vranic,_M.1984" class="citation journal cs1">Wasserman, D.H., Lickley, H.L.A. and Vranic, M. (1984). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC425308">"Interactions between glucagon and other counterregulatory hormones during normoglycemic and hypoglycemic exercise in dogs"</a>. <i>Journal of Clinical Investigation</i>. <b>74</b> (4): 1404–1413. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1172%2Fjci111551">10.1172/jci111551</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC425308">425308</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/6148356">6148356</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Investigation&rft.atitle=Interactions+between+glucagon+and+other+counterregulatory+hormones+during+normoglycemic+and+hypoglycemic+exercise+in+dogs&rft.volume=74&rft.issue=4&rft.pages=1404-1413&rft.date=1984&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC425308%23id-name%3DPMC&rft_id=info%3Apmid%2F6148356&rft_id=info%3Adoi%2F10.1172%2Fjci111551&rft.au=Wasserman%2C+D.H.%2C+Lickley%2C+H.L.A.+and+Vranic%2C+M.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC425308&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-19"><span class="mw-cite-backlink"><b><a href="#cite_ref-19">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBjorkman,_O.,_Miles,_P.,_Wasserman,_D.,_Lickley,_L._and_Vranic,_M.1988" class="citation journal cs1">Bjorkman, O., Miles, P., Wasserman, D., Lickley, L. and Vranic, M. (1988). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442622">"Regulation of glucose turnover during exercise in pancreatectomized, totally insulin deficient dogs: effects of β-adrenergic blockade"</a>. <i>Journal of Clinical Investigation</i>. <b>81</b> (6): 1759–1767. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1172%2Fjci113517">10.1172/jci113517</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442622">442622</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3290252">3290252</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Investigation&rft.atitle=Regulation+of+glucose+turnover+during+exercise+in+pancreatectomized%2C+totally+insulin+deficient+dogs%3A+effects+of+%CE%B2-adrenergic+blockade&rft.volume=81&rft.issue=6&rft.pages=1759-1767&rft.date=1988&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC442622%23id-name%3DPMC&rft_id=info%3Apmid%2F3290252&rft_id=info%3Adoi%2F10.1172%2Fjci113517&rft.au=Bjorkman%2C+O.%2C+Miles%2C+P.%2C+Wasserman%2C+D.%2C+Lickley%2C+L.+and+Vranic%2C+M.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC442622&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-20"><span class="mw-cite-backlink"><b><a href="#cite_ref-20">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChallis,_R.A.J.,_Vranic,_M._and_Radda,_G.K.1989" class="citation journal cs1">Challis, R.A.J., Vranic, M. and Radda, G.K. (1989). "Bioenergetic changes during contraction and recovery in diabetic rat skeletal muscle". <i>American Journal of Physiology</i>. <b>256</b> (1 Pt 1): E129–E137. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpendo.1989.256.1.E129">10.1152/ajpendo.1989.256.1.E129</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2643336">2643336</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Physiology&rft.atitle=Bioenergetic+changes+during+contraction+and+recovery+in+diabetic+rat+skeletal+muscle&rft.volume=256&rft.issue=1+Pt+1&rft.pages=E129-E137&rft.date=1989&rft_id=info%3Adoi%2F10.1152%2Fajpendo.1989.256.1.E129&rft_id=info%3Apmid%2F2643336&rft.au=Challis%2C+R.A.J.%2C+Vranic%2C+M.+and+Radda%2C+G.K.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-21"><span class="mw-cite-backlink"><b><a href="#cite_ref-21">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMiles,_P.,_Yamatani,_K.,_Lickley,_L._and_Vranic,_M.1991" class="citation journal cs1">Miles, P., Yamatani, K., Lickley, L. and Vranic, M. (1991). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC51004">"Mechanism of glucoregulatory responses to stress and their deficiency in diabetes"</a>. <i>Proceedings of the National Academy of Sciences</i>. <b>88</b> (4): 1296–1300. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1991PNAS...88.1296M">1991PNAS...88.1296M</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.88.4.1296">10.1073/pnas.88.4.1296</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC51004">51004</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1996330">1996330</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences&rft.atitle=Mechanism+of+glucoregulatory+responses+to+stress+and+their+deficiency+in+diabetes&rft.volume=88&rft.issue=4&rft.pages=1296-1300&rft.date=1991&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC51004%23id-name%3DPMC&rft_id=info%3Apmid%2F1996330&rft_id=info%3Adoi%2F10.1073%2Fpnas.88.4.1296&rft_id=info%3Abibcode%2F1991PNAS...88.1296M&rft.au=Miles%2C+P.%2C+Yamatani%2C+K.%2C+Lickley%2C+L.+and+Vranic%2C+M.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC51004&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-22"><span class="mw-cite-backlink"><b><a href="#cite_ref-22">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMarlissVranic2002" class="citation journal cs1">Marliss EB, Vranic M (2002). <a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.51.2007.s271">"Intense exercise has unique effects on both insulin release and its role in glucoregulation: Implications for diabetes"</a>. <i>Diabetes</i>. <b>51</b> (Suppl 1): S271–S283. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.51.2007.s271">10.2337/diabetes.51.2007.s271</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11815492">11815492</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Intense+exercise+has+unique+effects+on+both+insulin+release+and+its+role+in+glucoregulation%3A+Implications+for+diabetes&rft.volume=51&rft.issue=Suppl+1&rft.pages=S271-S283&rft.date=2002&rft_id=info%3Adoi%2F10.2337%2Fdiabetes.51.2007.s271&rft_id=info%3Apmid%2F11815492&rft.aulast=Marliss&rft.aufirst=EB&rft.au=Vranic%2C+M&rft_id=https%3A%2F%2Fdoi.org%2F10.2337%252Fdiabetes.51.2007.s271&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-23"><span class="mw-cite-backlink"><b><a href="#cite_ref-23">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKaniukKiralyBatesVranic2007" class="citation journal cs1">Kaniuk NA, Kiraly M, Bates HE, Vranic M, Volchuck A, Brumell JH (2007). <a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdb06-1160">"Ubiquitinated-protein aggregates form in pancreatic β-cells during diabetes-induced oxidative stress and are regulated by autophagy"</a>. <i>Diabetes</i>. <b>56</b> (4): 930–939. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdb06-1160">10.2337/db06-1160</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17395740">17395740</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Ubiquitinated-protein+aggregates+form+in+pancreatic+%CE%B2-cells+during+diabetes-induced+oxidative+stress+and+are+regulated+by+autophagy&rft.volume=56&rft.issue=4&rft.pages=930-939&rft.date=2007&rft_id=info%3Adoi%2F10.2337%2Fdb06-1160&rft_id=info%3Apmid%2F17395740&rft.aulast=Kaniuk&rft.aufirst=NA&rft.au=Kiraly%2C+M&rft.au=Bates%2C+HE&rft.au=Vranic%2C+M&rft.au=Volchuck%2C+A&rft.au=Brumell%2C+JH&rft_id=https%3A%2F%2Fdoi.org%2F10.2337%252Fdb06-1160&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-24"><span class="mw-cite-backlink"><b><a href="#cite_ref-24">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKiralyBatesKaniukYue2008" class="citation journal cs1">Kiraly MA, Bates HE, Kaniuk N, Yue JT, Brummel J, Matthews SG, Riddell MC, Vranic M (2008). "Swim training prevents hyperglycemia in ZDF rats: Mechanisms involved in partial maintenance of β-cell function". <i>American Journal of Physiology. Endocrinology and Metabolism</i>. <b>294</b> (2): E271–E283. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpendo.00476.2007">10.1152/ajpendo.00476.2007</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18029442">18029442</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:7317886">7317886</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Physiology.+Endocrinology+and+Metabolism&rft.atitle=Swim+training+prevents+hyperglycemia+in+ZDF+rats%3A+Mechanisms+involved+in+partial+maintenance+of+%CE%B2-cell+function&rft.volume=294&rft.issue=2&rft.pages=E271-E283&rft.date=2008&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A7317886%23id-name%3DS2CID&rft_id=info%3Apmid%2F18029442&rft_id=info%3Adoi%2F10.1152%2Fajpendo.00476.2007&rft.aulast=Kiraly&rft.aufirst=MA&rft.au=Bates%2C+HE&rft.au=Kaniuk%2C+N&rft.au=Yue%2C+JT&rft.au=Brummel%2C+J&rft.au=Matthews%2C+SG&rft.au=Riddell%2C+MC&rft.au=Vranic%2C+M&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-25"><span class="mw-cite-backlink"><b><a href="#cite_ref-25">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBatesSirekKiralyYue2008" class="citation journal cs1">Bates HE, Sirek AS, Kiraly MA, Yue JT, Goche Montes D, Matthews SG, Vranic M (2008). <a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fen.2007-1473">"Adaptation to mild, intermittent stress delays development of hyperglycemia in the ZDF rat independent of food intake: role of habituation of the HPA axis"</a>. <i>Endocrinology</i>. <b>149</b> (6): 2990–3001. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fen.2007-1473">10.1210/en.2007-1473</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18325996">18325996</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Endocrinology&rft.atitle=Adaptation+to+mild%2C+intermittent+stress+delays+development+of+hyperglycemia+in+the+ZDF+rat+independent+of+food+intake%3A+role+of+habituation+of+the+HPA+axis&rft.volume=149&rft.issue=6&rft.pages=2990-3001&rft.date=2008&rft_id=info%3Adoi%2F10.1210%2Fen.2007-1473&rft_id=info%3Apmid%2F18325996&rft.aulast=Bates&rft.aufirst=HE&rft.au=Sirek%2C+AS&rft.au=Kiraly%2C+MA&rft.au=Yue%2C+JT&rft.au=Goche+Montes%2C+D&rft.au=Matthews%2C+SG&rft.au=Vranic%2C+M&rft_id=https%3A%2F%2Fdoi.org%2F10.1210%252Fen.2007-1473&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-26"><span class="mw-cite-backlink"><b><a href="#cite_ref-26">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGiacca,_A.,_Fisher,_S.,_McCall,_R.H.,_Shi,_Z.Q._and_Vranic_M.1997" class="citation journal cs1">Giacca, A., Fisher, S., McCall, R.H., Shi, Z.Q. and Vranic M. (1997). <a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fen.138.3.999">"Direct and indirect effects of insulin in suppressing glucose production in depancreatized dogs: Role of glucagon"</a>. <i>Endocrinology</i>. <b>138</b> (3): 999–1007. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fen.138.3.999">10.1210/en.138.3.999</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9048601">9048601</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Endocrinology&rft.atitle=Direct+and+indirect+effects+of+insulin+in+suppressing+glucose+production+in+depancreatized+dogs%3A+Role+of+glucagon&rft.volume=138&rft.issue=3&rft.pages=999-1007&rft.date=1997&rft_id=info%3Adoi%2F10.1210%2Fen.138.3.999&rft_id=info%3Apmid%2F9048601&rft.au=Giacca%2C+A.%2C+Fisher%2C+S.%2C+McCall%2C+R.H.%2C+Shi%2C+Z.Q.+and+Vranic+M.&rft_id=https%3A%2F%2Fdoi.org%2F10.1210%252Fen.138.3.999&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-27"><span class="mw-cite-backlink"><b><a href="#cite_ref-27">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLewis,_G.F.,_Vranic,_M.,_Harley,_P.,_and_Giacca_A.1997" class="citation journal cs1">Lewis, G.F., Vranic, M., Harley, P., and Giacca A. (1997). "Fatty acids mediate the acute extrahepatic effects of insulin on hepatic glucose production in humans". <i>Diabetes</i>. <b>46</b> (7): 1111–1119. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.46.7.1111">10.2337/diabetes.46.7.1111</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9200644">9200644</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Fatty+acids+mediate+the+acute+extrahepatic+effects+of+insulin+on+hepatic+glucose+production+in+humans&rft.volume=46&rft.issue=7&rft.pages=1111-1119&rft.date=1997&rft_id=info%3Adoi%2F10.2337%2Fdiabetes.46.7.1111&rft_id=info%3Apmid%2F9200644&rft.au=Lewis%2C+G.F.%2C+Vranic%2C+M.%2C+Harley%2C+P.%2C+and+Giacca+A.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-28"><span class="mw-cite-backlink"><b><a href="#cite_ref-28">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLewis,_G.F.,_Giacca,_A.,_Vranic,_M._and_G._Steiner.1998" class="citation journal cs1">Lewis, G.F., Giacca, A., Vranic, M. and G. Steiner. (1998). "Acute direct and indirect effects of insulin on hepatic glucose and very low density lipoprotein (VLDL) production". <i>Current Opinion in Endocrinology, Diabetes and Obesity</i>. <b>5</b>: 235–245. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2F00060793-199811000-00001">10.1097/00060793-199811000-00001</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Current+Opinion+in+Endocrinology%2C+Diabetes+and+Obesity&rft.atitle=Acute+direct+and+indirect+effects+of+insulin+on+hepatic+glucose+and+very+low+density+lipoprotein+%28VLDL%29+production&rft.volume=5&rft.pages=235-245&rft.date=1998&rft_id=info%3Adoi%2F10.1097%2F00060793-199811000-00001&rft.au=Lewis%2C+G.F.%2C+Giacca%2C+A.%2C+Vranic%2C+M.+and+G.+Steiner.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-29"><span class="mw-cite-backlink"><b><a href="#cite_ref-29">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLewis,_G.H.,_Carpentier,_A.,_Vranic,_M._and_Giacca,_A.1999" class="citation journal cs1">Lewis, G.H., Carpentier, A., Vranic, M. and Giacca, A. (1999). <a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.48.3.570">"Resistance to insulin's direct hepatic effect in suppressing steady state glucose production in individuals with type 2 diabetes mellitus"</a>. <i>Diabetes</i>. <b>48</b> (3): 570–576. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.48.3.570">10.2337/diabetes.48.3.570</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10078558">10078558</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Resistance+to+insulin%27s+direct+hepatic+effect+in+suppressing+steady+state+glucose+production+in+individuals+with+type+2+diabetes+mellitus&rft.volume=48&rft.issue=3&rft.pages=570-576&rft.date=1999&rft_id=info%3Adoi%2F10.2337%2Fdiabetes.48.3.570&rft_id=info%3Apmid%2F10078558&rft.au=Lewis%2C+G.H.%2C+Carpentier%2C+A.%2C+Vranic%2C+M.+and+Giacca%2C+A.&rft_id=https%3A%2F%2Fdoi.org%2F10.2337%252Fdiabetes.48.3.570&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-30"><span class="mw-cite-backlink"><b><a href="#cite_ref-30">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFEfendic,_S.,_Wajngot,_A.,_Vranic,_M.1985" class="citation journal cs1">Efendic, S., Wajngot, A., Vranic, M. (1985). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC397687">"Increased activity of the glucose cycle in the liver: early characteristic of Type II diabetes"</a>. <i>Proceedings of the National Academy of Sciences</i>. <b>82</b> (9): 2965–2969. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/1985PNAS...82.2965E">1985PNAS...82.2965E</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.82.9.2965">10.1073/pnas.82.9.2965</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC397687">397687</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3857627">3857627</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences&rft.atitle=Increased+activity+of+the+glucose+cycle+in+the+liver%3A+early+characteristic+of+Type+II+diabetes&rft.volume=82&rft.issue=9&rft.pages=2965-2969&rft.date=1985&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC397687%23id-name%3DPMC&rft_id=info%3Apmid%2F3857627&rft_id=info%3Adoi%2F10.1073%2Fpnas.82.9.2965&rft_id=info%3Abibcode%2F1985PNAS...82.2965E&rft.au=Efendic%2C+S.%2C+Wajngot%2C+A.%2C+Vranic%2C+M.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC397687&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-31"><span class="mw-cite-backlink"><b><a href="#cite_ref-31">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFYamatani,_K.,_Shi,_Z.,_Giacca,_A.,_Gupta,_R.,_Fisher,_S.,_Lickley,_L._and_Vranic,_M.1992" class="citation journal cs1">Yamatani, K., Shi, Z., Giacca, A., Gupta, R., Fisher, S., Lickley, L. and Vranic, M. (1992). "Role of FFA-Glucose cycle in glucoregulation during exercise in total absence of insulin". <i>American Journal of Physiology. Endocrinology and Metabolism</i>. <b>263</b> (26): E646–E653. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpendo.1992.263.4.e646">10.1152/ajpendo.1992.263.4.e646</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1415684">1415684</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Physiology.+Endocrinology+and+Metabolism&rft.atitle=Role+of+FFA-Glucose+cycle+in+glucoregulation+during+exercise+in+total+absence+of+insulin&rft.volume=263&rft.issue=26&rft.pages=E646-E653&rft.date=1992&rft_id=info%3Adoi%2F10.1152%2Fajpendo.1992.263.4.e646&rft_id=info%3Apmid%2F1415684&rft.au=Yamatani%2C+K.%2C+Shi%2C+Z.%2C+Giacca%2C+A.%2C+Gupta%2C+R.%2C+Fisher%2C+S.%2C+Lickley%2C+L.+and+Vranic%2C+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-32"><span class="mw-cite-backlink"><b><a href="#cite_ref-32">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMarette,_A.,_Richardson,_J.M.,_Ramlal,_T.,_Balon,_T.W.,_Vranic,_M.,_Pessin,_J.F._and_Klip,_A.1992" class="citation journal cs1">Marette, A., Richardson, J.M., Ramlal, T., Balon, T.W., Vranic, M., Pessin, J.F. and Klip, A. (1992). "Abundance, localization, and insulin-induced translocation of glucose transporters in red and white muscle of rat hind limb". <i>American Journal of Physiology. Cell Physiology</i>. <b>263</b> (32): C443–C452. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpcell.1992.263.2.c443">10.1152/ajpcell.1992.263.2.c443</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1514590">1514590</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Physiology.+Cell+Physiology&rft.atitle=Abundance%2C+localization%2C+and+insulin-induced+translocation+of+glucose+transporters+in+red+and+white+muscle+of+rat+hind+limb&rft.volume=263&rft.issue=32&rft.pages=C443-C452&rft.date=1992&rft_id=info%3Adoi%2F10.1152%2Fajpcell.1992.263.2.c443&rft_id=info%3Apmid%2F1514590&rft.au=Marette%2C+A.%2C+Richardson%2C+J.M.%2C+Ramlal%2C+T.%2C+Balon%2C+T.W.%2C+Vranic%2C+M.%2C+Pessin%2C+J.F.+and+Klip%2C+A.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-33"><span class="mw-cite-backlink"><b><a href="#cite_ref-33">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFShi,_Z.Q.,_Giacca,_A.,_Fisher,_S.,_Hubert_Vidal,_van_de_Werve,_G._and_Vranic,_M.1994" class="citation journal cs1">Shi, Z.Q., Giacca, A., Fisher, S., Hubert Vidal, van de Werve, G. and Vranic, M. (1994). "Importance of substrate changes in the decrease of hepatic glucose cycling during insulin infusion and declining glycemia in the depancreatized dog". <i>Diabetes</i>. <b>43</b> (11): 1284–1290. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.43.11.1284">10.2337/diabetes.43.11.1284</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7926301">7926301</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Importance+of+substrate+changes+in+the+decrease+of+hepatic+glucose+cycling+during+insulin+infusion+and+declining+glycemia+in+the+depancreatized+dog&rft.volume=43&rft.issue=11&rft.pages=1284-1290&rft.date=1994&rft_id=info%3Adoi%2F10.2337%2Fdiabetes.43.11.1284&rft_id=info%3Apmid%2F7926301&rft.au=Shi%2C+Z.Q.%2C+Giacca%2C+A.%2C+Fisher%2C+S.%2C+Hubert+Vidal%2C+van+de+Werve%2C+G.+and+Vranic%2C+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-34"><span class="mw-cite-backlink"><b><a href="#cite_ref-34">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFTsakiridis,_T.,_Vranic,_M._and_Klip,_A.1994" class="citation journal cs1">Tsakiridis, T., Vranic, M. and Klip, A. (1994). <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0021-9258%2818%2943971-3">"Disassembly of the actin network inhibits insulin-dependent stimulation of glucose transport and prevents recruitment of glucose transporters in plasma membrane"</a>. <i>Journal of Biological Chemistry</i>. <b>269</b>: 29934–29942. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0021-9258%2818%2943971-3">10.1016/S0021-9258(18)43971-3</a></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Biological+Chemistry&rft.atitle=Disassembly+of+the+actin+network+inhibits+insulin-dependent+stimulation+of+glucose+transport+and+prevents+recruitment+of+glucose+transporters+in+plasma+membrane&rft.volume=269&rft.pages=29934-29942&rft.date=1994&rft_id=info%3Adoi%2F10.1016%2FS0021-9258%2818%2943971-3&rft.au=Tsakiridis%2C+T.%2C+Vranic%2C+M.+and+Klip%2C+A.&rft_id=https%3A%2F%2Fdoi.org%2F10.1016%252FS0021-9258%252818%252943971-3&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-35"><span class="mw-cite-backlink"><b><a href="#cite_ref-35">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMathoo,_J.M.R.,_Shi,_Z.Q.,_Klip,_A._and_Vranic,_M.1999" class="citation journal cs1">Mathoo, J.M.R., Shi, Z.Q., Klip, A. and Vranic, M. (1999). "Opposite effects of acute hypoglycemia and acute hyperglycemia on glucose transport and glucose transporters in perfused rat skeletal muscle". <i>Diabetes</i>. <b>48</b> (6): 1281–1288. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.48.6.1281">10.2337/diabetes.48.6.1281</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10342817">10342817</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Opposite+effects+of+acute+hypoglycemia+and+acute+hyperglycemia+on+glucose+transport+and+glucose+transporters+in+perfused+rat+skeletal+muscle&rft.volume=48&rft.issue=6&rft.pages=1281-1288&rft.date=1999&rft_id=info%3Adoi%2F10.2337%2Fdiabetes.48.6.1281&rft_id=info%3Apmid%2F10342817&rft.au=Mathoo%2C+J.M.R.%2C+Shi%2C+Z.Q.%2C+Klip%2C+A.+and+Vranic%2C+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-36"><span class="mw-cite-backlink"><b><a href="#cite_ref-36">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLickley,_H.L.A.,_Kemmer,_F.W.,_El-Tayeb,_K.M.A._and_Vranic,_M.1987" class="citation journal cs1">Lickley, H.L.A., Kemmer, F.W., El-Tayeb, K.M.A. and Vranic, M. (1987). <a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fbf00274224">"Importance of glucagon in the control of futile cycling as studied in alloxan-diabetic dogs"</a>. <i>Diabetologia</i>. <b>30</b> (3): 175–182. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fbf00274224">10.1007/bf00274224</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2884159">2884159</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetologia&rft.atitle=Importance+of+glucagon+in+the+control+of+futile+cycling+as+studied+in+alloxan-diabetic+dogs&rft.volume=30&rft.issue=3&rft.pages=175-182&rft.date=1987&rft_id=info%3Adoi%2F10.1007%2Fbf00274224&rft_id=info%3Apmid%2F2884159&rft.au=Lickley%2C+H.L.A.%2C+Kemmer%2C+F.W.%2C+El-Tayeb%2C+K.M.A.+and+Vranic%2C+M.&rft_id=https%3A%2F%2Fdoi.org%2F10.1007%252Fbf00274224&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-37"><span class="mw-cite-backlink"><b><a href="#cite_ref-37">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFEfendic,_S.,_Karlander,_S._and_Vranic,_M.1988" class="citation journal cs1">Efendic, S., Karlander, S. and Vranic, M. (1988). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442648">"Mild Type II diabetes markedly increases glucose cycling in the postabsorptive state and during glucose infusion irrespective of obesity"</a>. <i>Journal of Clinical Investigation</i>. <b>81</b> (6): 1953–1961. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1172%2Fjci113543">10.1172/jci113543</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442648">442648</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3290257">3290257</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Clinical+Investigation&rft.atitle=Mild+Type+II+diabetes+markedly+increases+glucose+cycling+in+the+postabsorptive+state+and+during+glucose+infusion+irrespective+of+obesity&rft.volume=81&rft.issue=6&rft.pages=1953-1961&rft.date=1988&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC442648%23id-name%3DPMC&rft_id=info%3Apmid%2F3290257&rft_id=info%3Adoi%2F10.1172%2Fjci113543&rft.au=Efendic%2C+S.%2C+Karlander%2C+S.+and+Vranic%2C+M.&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC442648&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-38"><span class="mw-cite-backlink"><b><a href="#cite_ref-38">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRastogi,_K.S.,_Lickley,_L.,_Jokay,_M.,_Efendic,_S._and_Vranic,_M.1990" class="citation journal cs1">Rastogi, K.S., Lickley, L., Jokay, M., Efendic, S. and Vranic, M. (1990). "Paradoxical reduction in pancreatic glucagon with normalization of somatostatin and decrease in insulin in normoglycemic alloxan-diabetic dogs: a putative mechanism of glucagon irresponsiveness to hypoglycemia". <i>Endocrinology</i>. <b>126</b> (2): 1096–1104. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fendo-126-2-1096">10.1210/endo-126-2-1096</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1967577">1967577</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Endocrinology&rft.atitle=Paradoxical+reduction+in+pancreatic+glucagon+with+normalization+of+somatostatin+and+decrease+in+insulin+in+normoglycemic+alloxan-diabetic+dogs%3A+a+putative+mechanism+of+glucagon+irresponsiveness+to+hypoglycemia&rft.volume=126&rft.issue=2&rft.pages=1096-1104&rft.date=1990&rft_id=info%3Adoi%2F10.1210%2Fendo-126-2-1096&rft_id=info%3Apmid%2F1967577&rft.au=Rastogi%2C+K.S.%2C+Lickley%2C+L.%2C+Jokay%2C+M.%2C+Efendic%2C+S.+and+Vranic%2C+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-39"><span class="mw-cite-backlink"><b><a href="#cite_ref-39">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFShi,_Z.Q.,_Rastogi,_K.S.,_Lekas,_M.,_Efendic,_S.,_Drucker,_D.J._and_Vranic,_M.1996" class="citation journal cs1">Shi, Z.Q., Rastogi, K.S., Lekas, M., Efendic, S., Drucker, D.J. and Vranic, M. (1996). <a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fendo.137.8.8754739">"Glucagon response to hypoglycemia is improved by insulin-independent restoration of normoglycemia in diabetic rats"</a>. <i>Endocrinology</i>. <b>137</b> (8): 3193–3199. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fendo.137.8.8754739">10.1210/endo.137.8.8754739</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8754739">8754739</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Endocrinology&rft.atitle=Glucagon+response+to+hypoglycemia+is+improved+by+insulin-independent+restoration+of+normoglycemia+in+diabetic+rats&rft.volume=137&rft.issue=8&rft.pages=3193-3199&rft.date=1996&rft_id=info%3Adoi%2F10.1210%2Fendo.137.8.8754739&rft_id=info%3Apmid%2F8754739&rft.au=Shi%2C+Z.Q.%2C+Rastogi%2C+K.S.%2C+Lekas%2C+M.%2C+Efendic%2C+S.%2C+Drucker%2C+D.J.+and+Vranic%2C+M.&rft_id=https%3A%2F%2Fdoi.org%2F10.1210%252Fendo.137.8.8754739&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span><span class="cs1-maint citation-comment"><code class="cs1-code">{{<a href="/wiki/Template:Cite_journal" title="Template:Cite journal">cite journal</a>}}</code>: CS1 maint: multiple names: authors list (<a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">link</a>)</span></span> </li> <li id="cite_note-40"><span class="mw-cite-backlink"><b><a href="#cite_ref-40">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChanChanInouyeVranic2001" class="citation journal cs1">Chan O, Chan S, Inouye K, Vranic M, Matthews SG (2001). <a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fen.142.11.4872">"Molecular regulation of the hypothalamo-pituitary-adrenocortical axis in streptozotocin-induced diabetes: effects of insulin treatment"</a>. <i>Endocrinology</i>. <b>142</b>: 4872–4879. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fen.142.11.4872">10.1210/en.142.11.4872</a></span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Endocrinology&rft.atitle=Molecular+regulation+of+the+hypothalamo-pituitary-adrenocortical+axis+in+streptozotocin-induced+diabetes%3A+effects+of+insulin+treatment&rft.volume=142&rft.pages=4872-4879&rft.date=2001&rft_id=info%3Adoi%2F10.1210%2Fen.142.11.4872&rft.aulast=Chan&rft.aufirst=O&rft.au=Chan%2C+S&rft.au=Inouye%2C+K&rft.au=Vranic%2C+M&rft.au=Matthews%2C+SG&rft_id=https%3A%2F%2Fdoi.org%2F10.1210%252Fen.142.11.4872&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-41"><span class="mw-cite-backlink"><b><a href="#cite_ref-41">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFInouyeShumChanMathoo2002" class="citation journal cs1">Inouye K, Shum K, Chan O, Mathoo J, Matthews SG, Vranic M (2002). "Effects of recurrent hyperinsulinemia with and without hypoglycemia on counterregulation in diabetic rats". <i>American Journal of Physiology. Endocrinology and Metabolism</i>. <b>282</b> (6): E1369–E1379. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpendo.00480.2001">10.1152/ajpendo.00480.2001</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12006368">12006368</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:588032">588032</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Physiology.+Endocrinology+and+Metabolism&rft.atitle=Effects+of+recurrent+hyperinsulinemia+with+and+without+hypoglycemia+on+counterregulation+in+diabetic+rats&rft.volume=282&rft.issue=6&rft.pages=E1369-E1379&rft.date=2002&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A588032%23id-name%3DS2CID&rft_id=info%3Apmid%2F12006368&rft_id=info%3Adoi%2F10.1152%2Fajpendo.00480.2001&rft.aulast=Inouye&rft.aufirst=K&rft.au=Shum%2C+K&rft.au=Chan%2C+O&rft.au=Mathoo%2C+J&rft.au=Matthews%2C+SG&rft.au=Vranic%2C+M&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-42"><span class="mw-cite-backlink"><b><a href="#cite_ref-42">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChanChanInouyeShum2002" class="citation journal cs1">Chan O, Chan S, Inouye K, Shum K, Bilinski D, Matthews SG, Vranic M (2002). <a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.51.6.1681">"Diabetes impairs hypothalamic-pituitary-adrenal (HPA) responses to hypoglycemia and insulin treatment normalizes HPA, but not epinephrine responses"</a>. <i>Diabetes</i>. <b>51</b> (6): 1681–1689. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdiabetes.51.6.1681">10.2337/diabetes.51.6.1681</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12031953">12031953</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Diabetes+impairs+hypothalamic-pituitary-adrenal+%28HPA%29+responses+to+hypoglycemia+and+insulin+treatment+normalizes+HPA%2C+but+not+epinephrine+responses&rft.volume=51&rft.issue=6&rft.pages=1681-1689&rft.date=2002&rft_id=info%3Adoi%2F10.2337%2Fdiabetes.51.6.1681&rft_id=info%3Apmid%2F12031953&rft.aulast=Chan&rft.aufirst=O&rft.au=Chan%2C+S&rft.au=Inouye%2C+K&rft.au=Shum%2C+K&rft.au=Bilinski%2C+D&rft.au=Matthews%2C+SG&rft.au=Vranic%2C+M&rft_id=https%3A%2F%2Fdoi.org%2F10.2337%252Fdiabetes.51.6.1681&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-43"><span class="mw-cite-backlink"><b><a href="#cite_ref-43">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFInouyeYueChanBurdett2006" class="citation journal cs1">Inouye K, Yue JT, Chan O, Burdett E, Kim T, Akirav EM, Park E, Riddel MC, Matthews SG, Vranic M (2006). <a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fen.2005-1040">"Effects of insulin treatment without and with recurrent hypoglycemia on hypoglycemic counterregulation and adrenal catecholamine-synthesizing enzymes in diabetic rats"</a>. <i>Endocrinology</i>. <b>147</b> (4): 1860–1870. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1210%2Fen.2005-1040">10.1210/en.2005-1040</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16396986">16396986</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Endocrinology&rft.atitle=Effects+of+insulin+treatment+without+and+with+recurrent+hypoglycemia+on+hypoglycemic+counterregulation+and+adrenal+catecholamine-synthesizing+enzymes+in+diabetic+rats&rft.volume=147&rft.issue=4&rft.pages=1860-1870&rft.date=2006&rft_id=info%3Adoi%2F10.1210%2Fen.2005-1040&rft_id=info%3Apmid%2F16396986&rft.aulast=Inouye&rft.aufirst=K&rft.au=Yue%2C+JT&rft.au=Chan%2C+O&rft.au=Burdett%2C+E&rft.au=Kim%2C+T&rft.au=Akirav%2C+EM&rft.au=Park%2C+E&rft.au=Riddel%2C+MC&rft.au=Matthews%2C+SG&rft.au=Vranic%2C+M&rft_id=https%3A%2F%2Fdoi.org%2F10.1210%252Fen.2005-1040&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-44"><span class="mw-cite-backlink"><b><a href="#cite_ref-44">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFYueBurdettGiaccaEfendic2012" class="citation journal cs1">Yue JT, Burdett E, Giacca A, Efendic S, Vranic M (2012). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237655">"Somatostatin receptor type 2 antagonism improves glucagon and corticosterone counterregulatory responses to hypoglycemia in streptozotocin-induced diabetic rats"</a>. <i>Diabetes</i>. <b>61</b> (1): 197–207. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdb11-0690">10.2337/db11-0690</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237655">3237655</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/22106159">22106159</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Somatostatin+receptor+type+2+antagonism+improves+glucagon+and+corticosterone+counterregulatory+responses+to+hypoglycemia+in+streptozotocin-induced+diabetic+rats&rft.volume=61&rft.issue=1&rft.pages=197-207&rft.date=2012&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3237655%23id-name%3DPMC&rft_id=info%3Apmid%2F22106159&rft_id=info%3Adoi%2F10.2337%2Fdb11-0690&rft.aulast=Yue&rft.aufirst=JT&rft.au=Burdett%2C+E&rft.au=Giacca%2C+A&rft.au=Efendic%2C+S&rft.au=Vranic%2C+M&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3237655&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-45"><span class="mw-cite-backlink"><b><a href="#cite_ref-45">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGaisanoMacDonaldVranic2012" class="citation journal cs1">Gaisano HY, MacDonald PE, Vranic M (2012). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432929">"Review article: Glucagon secretion and signaling in the development of diabetes"</a>. <i>Frontiers in Physiology</i>. <b>3</b>: 1–12. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.3389%2Ffphys.2012.00349">10.3389/fphys.2012.00349</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432929">3432929</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/22969729">22969729</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Frontiers+in+Physiology&rft.atitle=Review+article%3A+Glucagon+secretion+and+signaling+in+the+development+of+diabetes&rft.volume=3&rft.pages=1-12&rft.date=2012&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3432929%23id-name%3DPMC&rft_id=info%3Apmid%2F22969729&rft_id=info%3Adoi%2F10.3389%2Ffphys.2012.00349&rft.aulast=Gaisano&rft.aufirst=HY&rft.au=MacDonald%2C+PE&rft.au=Vranic%2C+M&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3432929&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-46"><span class="mw-cite-backlink"><b><a href="#cite_ref-46">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFYueBurdettCoyEfendic2013" class="citation journal cs1">Yue JT, Burdett E, Coy DH, Efendic S, Riddell M, Vranic M (2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712070">"Amelioration of hypoglycemia via somatostatin receptor type 2 antagonism in recurrently hypoglycemic diabetic rats"</a>. <i>Diabetes</i>. <b>62</b> (7): 2215–2222. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdb12-1523">10.2337/db12-1523</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712070">3712070</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23434929">23434929</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Amelioration+of+hypoglycemia+via+somatostatin+receptor+type+2+antagonism+in+recurrently+hypoglycemic+diabetic+rats&rft.volume=62&rft.issue=7&rft.pages=2215-2222&rft.date=2013&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3712070%23id-name%3DPMC&rft_id=info%3Apmid%2F23434929&rft_id=info%3Adoi%2F10.2337%2Fdb12-1523&rft.aulast=Yue&rft.aufirst=JT&rft.au=Burdett%2C+E&rft.au=Coy%2C+DH&rft.au=Efendic%2C+S&rft.au=Riddell%2C+M&rft.au=Vranic%2C+M&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3712070&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-47"><span class="mw-cite-backlink"><b><a href="#cite_ref-47">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFYueGocheBatesKiraly2007" class="citation journal cs1">Yue JT, Goche MD, Bates HE, Kiraly MA, Matthews SG, Vranic M (2007). "Recurrent stress attenuates expression of genes regulating hypoglycemic and restraint stress responses in diabetic rats". <i>Diabetes</i>. <b>56</b> (Suppl 1): A101.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Recurrent+stress+attenuates+expression+of+genes+regulating+hypoglycemic+and+restraint+stress+responses+in+diabetic+rats&rft.volume=56&rft.issue=Suppl+1&rft.pages=A101&rft.date=2007&rft.aulast=Yue&rft.aufirst=JT&rft.au=Goche%2C+MD&rft.au=Bates%2C+HE&rft.au=Kiraly%2C+MA&rft.au=Matthews%2C+SG&rft.au=Vranic%2C+M&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> <li id="cite_note-48"><span class="mw-cite-backlink"><b><a href="#cite_ref-48">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFVranic,_M.2010" class="citation journal cs1">Vranic, M. (2010). "Odyssey between Scylla and Charybdis through storms of carbohydrate metabolism and diabetes: a career retrospective". <i>American Journal of Physiology. Endocrinology and Metabolism</i>. <b>299</b> (6): E849–E867. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpendo.00344.2010">10.1152/ajpendo.00344.2010</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20823450">20823450</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:24855879">24855879</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Physiology.+Endocrinology+and+Metabolism&rft.atitle=Odyssey+between+Scylla+and+Charybdis+through+storms+of+carbohydrate+metabolism+and+diabetes%3A+a+career+retrospective&rft.volume=299&rft.issue=6&rft.pages=E849-E867&rft.date=2010&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A24855879%23id-name%3DS2CID&rft_id=info%3Apmid%2F20823450&rft_id=info%3Adoi%2F10.1152%2Fajpendo.00344.2010&rft.au=Vranic%2C+M.&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMladen+Vranic" class="Z3988"></span></span> </li> </ol></div></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · ";font-weight:bold}.mw-parser-output .hlist dd:last-child::after,.mw-parser-output .hlist dt:last-child::after,.mw-parser-output .hlist li:last-child::after{content:none}.mw-parser-output .hlist dd dd:first-child::before,.mw-parser-output .hlist dd dt:first-child::before,.mw-parser-output .hlist dd li:first-child::before,.mw-parser-output .hlist dt dd:first-child::before,.mw-parser-output .hlist dt dt:first-child::before,.mw-parser-output .hlist dt li:first-child::before,.mw-parser-output .hlist li dd:first-child::before,.mw-parser-output .hlist li dt:first-child::before,.mw-parser-output .hlist li li:first-child::before{content:" (";font-weight:normal}.mw-parser-output .hlist dd dd:last-child::after,.mw-parser-output .hlist dd dt:last-child::after,.mw-parser-output .hlist dd li:last-child::after,.mw-parser-output .hlist dt dd:last-child::after,.mw-parser-output .hlist dt dt:last-child::after,.mw-parser-output .hlist dt li:last-child::after,.mw-parser-output .hlist li dd:last-child::after,.mw-parser-output .hlist li dt:last-child::after,.mw-parser-output .hlist li li:last-child::after{content:")";font-weight:normal}.mw-parser-output .hlist ol{counter-reset:listitem}.mw-parser-output .hlist ol>li{counter-increment:listitem}.mw-parser-output .hlist ol>li::before{content:" "counter(listitem)"\a0 "}.mw-parser-output .hlist dd ol>li:first-child::before,.mw-parser-output .hlist dt ol>li:first-child::before,.mw-parser-output .hlist li ol>li:first-child::before{content:" ("counter(listitem)"\a0 "}</style><style data-mw-deduplicate="TemplateStyles:r1236075235">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output .navbox+.navbox-styles+.navbox{margin-top:-1px}.mw-parser-output .navbox-inner,.mw-parser-output .navbox-subgroup{width:100%}.mw-parser-output .navbox-group,.mw-parser-output .navbox-title,.mw-parser-output .navbox-abovebelow{padding:0.25em 1em;line-height:1.5em;text-align:center}.mw-parser-output .navbox-group{white-space:nowrap;text-align:right}.mw-parser-output .navbox,.mw-parser-output .navbox-subgroup{background-color:#fdfdfd}.mw-parser-output .navbox-list{line-height:1.5em;border-color:#fdfdfd}.mw-parser-output .navbox-list-with-group{text-align:left;border-left-width:2px;border-left-style:solid}.mw-parser-output tr+tr>.navbox-abovebelow,.mw-parser-output tr+tr>.navbox-group,.mw-parser-output tr+tr>.navbox-image,.mw-parser-output tr+tr>.navbox-list{border-top:2px solid #fdfdfd}.mw-parser-output .navbox-title{background-color:#ccf}.mw-parser-output .navbox-abovebelow,.mw-parser-output .navbox-group,.mw-parser-output .navbox-subgroup .navbox-title{background-color:#ddf}.mw-parser-output .navbox-subgroup .navbox-group,.mw-parser-output .navbox-subgroup .navbox-abovebelow{background-color:#e6e6ff}.mw-parser-output .navbox-even{background-color:#f7f7f7}.mw-parser-output .navbox-odd{background-color:transparent}.mw-parser-output .navbox .hlist td dl,.mw-parser-output .navbox .hlist td ol,.mw-parser-output .navbox .hlist td ul,.mw-parser-output .navbox td.hlist dl,.mw-parser-output .navbox td.hlist ol,.mw-parser-output .navbox td.hlist ul{padding:0.125em 0}.mw-parser-output .navbox .navbar{display:block;font-size:100%}.mw-parser-output .navbox-title .navbar{float:left;text-align:left;margin-right:0.5em}body.skin--responsive .mw-parser-output .navbox-image img{max-width:none!important}@media print{body.ns-0 .mw-parser-output .navbox{display:none!important}}</style></div><div role="navigation" class="navbox" aria-labelledby="Inductees_into_the_Canadian_Medical_Hall_of_Fame" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Canadian_Medical_Hall_of_Fame" title="Template:Canadian Medical Hall of Fame"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Canadian_Medical_Hall_of_Fame" title="Template talk:Canadian Medical Hall of Fame"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Canadian_Medical_Hall_of_Fame" title="Special:EditPage/Template:Canadian Medical Hall of Fame"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Inductees_into_the_Canadian_Medical_Hall_of_Fame" style="font-size:114%;margin:0 4em">Inductees into the <a href="/wiki/Canadian_Medical_Hall_of_Fame" title="Canadian Medical Hall of Fame">Canadian Medical Hall of Fame</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>A</b></li> <li><a href="/wiki/Maude_Abbott" title="Maude Abbott">Maude Abbott</a></li> <li><a href="/wiki/Oswald_Avery" title="Oswald Avery">Oswald Avery</a></li> <li><a href="/wiki/Albert_Aguayo" title="Albert Aguayo">Albert Aguayo</a> <b>B</b></li> <li><a href="/wiki/Elizabeth_Bagshaw" title="Elizabeth Bagshaw">Elizabeth Bagshaw</a></li> <li><a href="/wiki/Frederick_Banting" title="Frederick Banting">Frederick Banting</a></li> <li><a href="/wiki/Henry_J._M._Barnett" title="Henry J. M. Barnett">Henry J. M. Barnett</a></li> <li><a href="/wiki/Murray_Barr" title="Murray Barr">Murray Barr</a></li> <li><a href="/wiki/Charles_Thomas_Beer" title="Charles Thomas Beer">Charles Thomas Beer</a></li> <li><a href="/wiki/John_Bell_(physician)" title="John Bell (physician)">John Bel</a></li> <li><a href="/wiki/Bernard_Belleau" title="Bernard Belleau">Bernard Belleau</a></li> <li><a href="/w/index.php?title=Philip_B._Berger&action=edit&redlink=1" class="new" title="Philip B. Berger (page does not exist)">Philip B. Berger</a></li> <li><a href="/wiki/Michel_G._Bergeron" title="Michel G. Bergeron">Michel G. Bergeron</a></li> <li><a href="/wiki/Alan_Bernstein" title="Alan Bernstein">Alan Bernstein</a></li> <li><a href="/wiki/Charles_Best_(medical_scientist)" title="Charles Best (medical scientist)">Charles Best</a></li> <li><a href="/wiki/Norman_Bethune" title="Norman Bethune">Norman Bethune</a></li> <li><a href="/wiki/John_Bienenstock" title="John Bienenstock">John Bienenstock</a></li> <li><a href="/wiki/Wilfred_Gordon_Bigelow" title="Wilfred Gordon Bigelow">Wilfred Gordon Bigelow</a></li> <li><a href="/wiki/Michael_Bliss" title="Michael Bliss">Michael Bliss</a></li> <li><a href="/wiki/Stephen_Blizzard" title="Stephen Blizzard">Stephen Blizzard</a></li> <li><a href="/wiki/Adolfo_J._de_Bold" title="Adolfo J. de Bold">Adolfo J. de Bold</a></li> <li><a href="/wiki/Roberta_Bondar" title="Roberta Bondar">Roberta Bondar</a></li> <li><a href="/wiki/John_Bradley_(doctor)" title="John Bradley (doctor)">John Bradley</a></li> <li><a href="/wiki/Henri_Breault" title="Henri Breault">Henri Breault</a></li> <li><a href="/wiki/G._Malcolm_Brown" title="G. Malcolm Brown">G. Malcolm Brown</a></li> <li><a href="/wiki/John_Browne_(scientist)" title="John Browne (scientist)">John Browne</a></li> <li><a href="/wiki/Alan_C._Burton" title="Alan C. Burton">Alan C. Burton</a> <b>C</b></li> <li><a href="/w/index.php?title=Elaine_A._Carty&action=edit&redlink=1" class="new" title="Elaine A. Carty (page does not exist)">Elaine A. Carty</a></li> <li><a href="/wiki/Brock_Chisholm" title="Brock Chisholm">Brock Chisholm</a></li> <li><a href="/wiki/Harvey_Max_Chochinov" class="mw-redirect" title="Harvey Max Chochinov">Harvey Max Chochinov</a></li> <li><a href="/wiki/Bruce_Chown" title="Bruce Chown">Bruce Chown</a></li> <li><a href="/wiki/Michel_Chr%C3%A9tien" title="Michel Chrétien">Michel Chrétien</a></li> <li><a href="/wiki/William_Arthur_Cochrane" title="William Arthur Cochrane">William Arthur Cochrane</a></li> <li><a href="/wiki/May_Cohen" title="May Cohen">May Cohen</a></li> <li><a href="/wiki/James_Collip" title="James Collip">James Collip</a></li> <li><a href="/wiki/Douglas_Harold_Copp" title="Douglas Harold Copp">Douglas Harold Copp</a></li> <li><a href="/wiki/Max_Cynader" title="Max Cynader">Max Cynader</a> <b>D</b></li> <li><a href="/wiki/Paul_David_(cardiologist)" title="Paul David (cardiologist)">Paul David</a></li> <li><a href="/wiki/Naranjan_Dhalla" title="Naranjan Dhalla">Naranjan Dhalla</a></li> <li><a href="/w/index.php?title=Thomas_A._Dignan&action=edit&redlink=1" class="new" title="Thomas A. Dignan (page does not exist)">Thomas A. Dignan</a></li> <li><a href="/wiki/John_Dirks_(physician)" title="John Dirks (physician)">John Dirks</a></li> <li><a href="/wiki/James_Dosman" title="James Dosman">James Dosman</a></li> <li><a href="/wiki/Tommy_Douglas" title="Tommy Douglas">Tommy Douglas</a></li> <li><a href="/wiki/Charles_George_Drake" title="Charles George Drake">Charles George Drake</a></li> <li><a href="/wiki/Daniel_J._Drucker" title="Daniel J. Drucker">Daniel J. Drucker</a></li> <li><a href="/wiki/Jacalyn_Duffin" title="Jacalyn Duffin">Jacalyn Duffin</a></li> <li><a href="/wiki/Jean_Dussault" title="Jean Dussault">Jean Dussault</a> <b>E</b></li> <li><a href="/wiki/Connie_Eaves" title="Connie Eaves">Connie Eaves</a></li> <li><a href="/wiki/John_Robert_Evans" title="John Robert Evans">John Robert Evans</a> <b>F</b></li> <li><a href="/wiki/Ray_Farquharson" title="Ray Farquharson">Ray Farquharson</a></li> <li><a href="/wiki/Sylvia_Fedoruk" title="Sylvia Fedoruk">Sylvia Fedoruk</a></li> <li><a href="/wiki/William_Feindel" title="William Feindel">William Feindel</a></li> <li><a href="/wiki/Brett_Finlay" title="Brett Finlay">Brett Finlay</a></li> <li><a href="/wiki/C._Miller_Fisher" title="C. Miller Fisher">C. Miller Fisher</a></li> <li><a href="/wiki/John_G._FitzGerald" title="John G. FitzGerald">John G. FitzGerald</a></li> <li><a href="/wiki/Claude_Fortier" title="Claude Fortier">Claude Fortier</a></li> <li><a href="/wiki/Terry_Fox" title="Terry Fox">Terry Fox</a></li> <li><a href="/wiki/Armand_Frappier" title="Armand Frappier">Armand Frappier</a></li> <li><a href="/wiki/Clarke_Fraser" title="Clarke Fraser">Clarke Fraser</a></li> <li><a href="/wiki/Henry_Friesen" title="Henry Friesen">Henry Friesen</a> <b>G</b></li> <li><a href="/wiki/William_Gallie" title="William Gallie">William Gallie</a></li> <li><a href="/wiki/Jacques_Genest" title="Jacques Genest">Jacques Genest</a></li> <li><a href="/wiki/Gustave_Gingras" title="Gustave Gingras">Gustave Gingras</a></li> <li><a href="/wiki/Phil_Gold" title="Phil Gold">Phil Gold</a></li> <li><a href="/wiki/Richard_Goldbloom" title="Richard Goldbloom">Richard Goldbloom</a></li> <li><a href="/wiki/Jean_Gray_(academic)" class="mw-redirect" title="Jean Gray (academic)">Jean Gray</a></li> <li><a href="/wiki/Wilfred_Grenfell" title="Wilfred Grenfell">Wilfred Grenfell</a></li> <li><a href="/wiki/Gordon_Guyatt" title="Gordon Guyatt">Gordon Guyatt</a> <b>H</b></li> <li><a href="/wiki/Vladimir_Hachinski" title="Vladimir Hachinski">Vladimir Hachinski</a></li> <li><a href="/wiki/Antoine_Hakim" title="Antoine Hakim">Antoine Hakim</a></li> <li><a href="/wiki/Emmett_Matthew_Hall" title="Emmett Matthew Hall">Emmett Matthew Hall</a></li> <li><a href="/wiki/Judith_Goslin_Hall" title="Judith Goslin Hall">Judith Goslin Hall</a></li> <li><a href="/wiki/Michael_R._Hayden" title="Michael R. Hayden">Michael R. Hayden</a></li> <li><a href="/wiki/Donald_Olding_Hebb" class="mw-redirect" title="Donald Olding Hebb">Donald Olding Hebb</a></li> <li><a href="/wiki/Carol_Pearl_Herbert" title="Carol Pearl Herbert">Carol Herbert</a></li> <li><a href="/wiki/F%C3%A9lix_d%27Herelle" class="mw-redirect" title="Félix d'Herelle">Félix d'Herelle</a></li> <li><a href="/wiki/Jack_Hirsh" title="Jack Hirsh">Jack Hirsh</a></li> <li><a href="/wiki/Charles_Hollenberg" title="Charles Hollenberg">Charles Hollenberg</a></li> <li><a href="/wiki/James_C._Hogg" title="James C. Hogg">James C. Hogg</a></li> <li><a href="/wiki/David_Hubel" class="mw-redirect" title="David Hubel">David Hubel</a></li> <li><a href="/wiki/Charles_B._Huggins" class="mw-redirect" title="Charles B. Huggins">Charles B. Huggins</a> <b>J</b></li> <li><a href="/wiki/Herbert_Jasper" title="Herbert Jasper">Herbert Jasper</a></li> <li><a href="/wiki/David_J._Jenkins" title="David J. Jenkins">David J. Jenkins</a></li> <li><a href="/wiki/Harold_E._Johns" title="Harold E. Johns">Harold E. Johns</a> <b>K</b></li> <li><a href="/wiki/Wilbert_Keon" title="Wilbert Keon">Wilbert Keon</a></li> <li><a href="/wiki/Leonora_King" title="Leonora King">Leonora King</a> <b>L</b></li> <li><a href="/wiki/Marc_Lalonde" title="Marc Lalonde">Marc Lalonde</a></li> <li><a href="/wiki/Bernard_Langer_(surgeon)" title="Bernard Langer (surgeon)">Bernard Langer</a></li> <li><a href="/wiki/Charles_Philippe_Leblond" title="Charles Philippe Leblond">Charles Philippe Leblond</a></li> <li><a href="/wiki/Maurice_LeClair" title="Maurice LeClair">Maurice LeClair</a></li> <li><a href="/wiki/Heinz_Lehmann" title="Heinz Lehmann">Heinz Lehmann</a></li> <li><a href="/wiki/Peter_Lougheed" title="Peter Lougheed">Peter Lougheed</a> <b>M</b></li> <li><a href="/wiki/Jeanne_Mance" title="Jeanne Mance">Jeanne Mance</a></li> <li><a href="/wiki/Ernest_McCulloch" title="Ernest McCulloch">Ernest McCulloch</a></li> <li><a href="/wiki/John_McEachern" title="John McEachern">John McEachern</a></li> <li><a href="/wiki/Walter_Mackenzie" title="Walter Mackenzie">Walter Mackenzie</a></li> <li><a href="/wiki/Peter_Macklem" title="Peter Macklem">Peter Macklem</a></li> <li><a href="/wiki/David_MacLennan" title="David MacLennan">David MacLennan</a></li> <li><a href="/wiki/John_Macleod_(physiologist)" title="John Macleod (physiologist)">John Macleod</a></li> <li><a href="/wiki/John_McCrae" title="John McCrae">John McCrae</a></li> <li><a href="/wiki/Ian_McWhinney" title="Ian McWhinney">Ian McWhinney</a></li> <li><a href="/wiki/Tak_Wah_Mak" title="Tak Wah Mak">Tak Wah Mak</a></li> <li><a href="/wiki/Marco_Marra" title="Marco Marra">Marco Marra</a></li> <li><a href="/wiki/Joseph_B._Martin" title="Joseph B. Martin">Joseph B. Martin</a></li> <li><a href="/wiki/Pierre_Masson" title="Pierre Masson">Pierre Masson</a></li> <li><a href="/wiki/Jonathan_Campbell_Meakins" title="Jonathan Campbell Meakins">Jonathan Campbell Meakins</a></li> <li><a href="/wiki/Maud_Menten" title="Maud Menten">Maud Menten</a></li> <li><a href="/wiki/Ronald_Melzack" title="Ronald Melzack">Ronald Melzack</a></li> <li><a href="/wiki/Brenda_Milner" title="Brenda Milner">Brenda Milner</a></li> <li><a href="/wiki/Julio_Montaner" title="Julio Montaner">Julio Montaner</a></li> <li><a href="/wiki/Frederick_Montizambert" title="Frederick Montizambert">Frederick Montizambert</a></li> <li><a href="/wiki/Balfour_Mount" title="Balfour Mount">Balfour Mount</a></li> <li><a href="/wiki/Thomas_John_Murray" title="Thomas John Murray">Thomas John Murray</a></li> <li><a href="/wiki/Fraser_Mustard" class="mw-redirect" title="Fraser Mustard">Fraser Mustard</a></li> <li><a href="/wiki/William_Thornton_Mustard" title="William Thornton Mustard">William Thornton Mustard</a> <b>N</b></li> <li><a href="/wiki/Arnold_Naimark" title="Arnold Naimark">Arnold Naimark</a></li> <li><a href="/wiki/David_Naylor" title="David Naylor">David Naylor</a></li> <li><a href="/wiki/Robert_Noble_(physician)" title="Robert Noble (physician)">Robert Noble</a> <b>O</b></li> <li><a href="/wiki/Annette_O%27Connor" title="Annette O'Connor">Annette O'Connor</a></li> <li><a href="/wiki/William_Osler" title="William Osler">William Osler</a> <b>P</b></li> <li><a href="/wiki/Anthony_Pawson" class="mw-redirect" title="Anthony Pawson">Anthony Pawson</a></li> <li><a href="/wiki/Wilder_Penfield" title="Wilder Penfield">Wilder Penfield</a></li> <li><a href="/wiki/Vera_Peters" title="Vera Peters">Vera Peters</a> <b>Q</b></li> <li><a href="/wiki/R%C3%A9mi_Quirion" title="Rémi Quirion">Rémi Quirion</a> <b>R</b></li> <li><a href="/wiki/Cheryl_Rockman-Greenberg" title="Cheryl Rockman-Greenberg">Cheryl Rockman-Greenberg</a></li> <li><a href="/wiki/Allan_Ronald" title="Allan Ronald">Allan Ronald</a></li> <li><a href="/wiki/Noralou_P._Roos" title="Noralou P. Roos">Noralou P. Roos</a></li> <li><a href="/w/index.php?title=Jean-Lucien_Rouleau&action=edit&redlink=1" class="new" title="Jean-Lucien Rouleau (page does not exist)">Jean-Lucien Rouleau</a></li> <li><a href="/wiki/Claude_Roy_(physician)" title="Claude Roy (physician)">Claude Roy</a></li> <li><a href="/wiki/Ian_Rusted" title="Ian Rusted">Ian Rusted</a> <b>S</b></li> <li><a href="/wiki/David_Sackett" title="David Sackett">David Sackett</a></li> <li><a href="/wiki/Robert_B._Salter" title="Robert B. Salter">Robert B. Salter</a></li> <li><a href="/wiki/Charles_Scriver" title="Charles Scriver">Charles Scriver</a></li> <li><a href="/wiki/Hans_Selye" title="Hans Selye">Hans Selye</a></li> <li><a href="/wiki/Louis_Siminovitch" title="Louis Siminovitch">Louis Siminovitch</a></li> <li><a href="/wiki/F._Estelle_R._Simons" title="F. Estelle R. Simons">F. Estelle R. Simons</a></li> <li><a href="/wiki/Duncan_G._Sinclair" title="Duncan G. Sinclair">Duncan G. Sinclair</a></li> <li><a href="/wiki/Michael_Smith_(chemist)" title="Michael Smith (chemist)">Michael Smith</a></li> <li><a href="/wiki/Nahum_Sonenberg" title="Nahum Sonenberg">Nahum Sonenberg</a></li> <li><a href="/wiki/Bette_Stephenson" title="Bette Stephenson">Bette Stephenson</a></li> <li><a href="/wiki/Calvin_Stiller" title="Calvin Stiller">Calvin Stiller</a></li> <li><a href="/wiki/Emily_Stowe" title="Emily Stowe">Emily Stowe</a> <b>T</b></li> <li><a href="/wiki/Charles_Tator" title="Charles Tator">Charles Tator</a></li> <li><a href="/wiki/Lucille_Teasdale-Corti" title="Lucille Teasdale-Corti">Lucille Teasdale-Corti</a></li> <li><a href="/wiki/James_Till" title="James Till">James Till</a></li> <li><a href="/wiki/Lap-Chee_Tsui" title="Lap-Chee Tsui">Lap-Chee Tsui</a></li> <li><a href="/wiki/Endel_Tulving" title="Endel Tulving">Endel Tulving</a></li> <li><a href="/wiki/Sir_Charles_Tupper" class="mw-redirect" title="Sir Charles Tupper">Sir Charles Tupper</a></li> <li><a href="/wiki/D._Lorne_Tyrrell" title="D. Lorne Tyrrell">D. Lorne Tyrrell</a> <b>V</b></li> <li><a class="mw-selflink selflink">Mladen Vranic</a> <b>W</b></li> <li><a href="/wiki/Mark_Wainberg" title="Mark Wainberg">Mark Wainberg</a></li> <li><a href="/wiki/Samuel_Weiss_(neurobiologist)" title="Samuel Weiss (neurobiologist)">Samuel Weiss</a></li> <li><a href="/wiki/Ronald_Worton" title="Ronald Worton">Ronald Worton</a> <b>Y</b></li> <li><a href="/wiki/Marie-Marguerite_d%27Youville" title="Marie-Marguerite d'Youville">Marie-Marguerite d'Youville</a></li> <li><a href="/wiki/Salim_Yusuf" title="Salim Yusuf">Salim Yusuf</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox authority-control" aria-labelledby="Authority_control_databases_frameless&#124;text-top&#124;10px&#124;alt=Edit_this_at_Wikidata&#124;link=https&#58;//www.wikidata.org/wiki/Q16091666#identifiers&#124;class=noprint&#124;Edit_this_at_Wikidata" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Authority_control_databases_frameless&#124;text-top&#124;10px&#124;alt=Edit_this_at_Wikidata&#124;link=https&#58;//www.wikidata.org/wiki/Q16091666#identifiers&#124;class=noprint&#124;Edit_this_at_Wikidata" style="font-size:114%;margin:0 4em"><a href="/wiki/Help:Authority_control" title="Help:Authority control">Authority control databases</a> <span class="mw-valign-text-top noprint" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q16091666#identifiers" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">International</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul><li><span class="uid"><a rel="nofollow" class="external text" href="https://isni.org/isni/0000000034591743">ISNI</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://viaf.org/viaf/1431041">VIAF</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://id.oclc.org/worldcat/entity/E39PBJmhPjqHbxf3pQcBTp9qwC">WorldCat</a></span></li></ul></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">National</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul><li><span class="uid"><a rel="nofollow" class="external text" href="https://id.loc.gov/authorities/n85024673">United States</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="http://data.bibliotheken.nl/id/thes/p071178775">Netherlands</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="https://authority.bibsys.no/authority/rest/authorities/html/90220390">Norway</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="http://katalog.nsk.hr/F/?func=direct&doc_number=000075440&local_base=nsk10">Croatia</a></span></li><li><span class="uid"><a rel="nofollow" class="external text" href="http://olduli.nli.org.il/F/?func=find-b&local_base=NLX10&find_code=UID&request=987007325350805171">Israel</a></span></li></ul></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Academics</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul><li><span class="uid"><a rel="nofollow" class="external text" href="https://ci.nii.ac.jp/author/DA0094160X?l=en">CiNii</a></span></li></ul></div></td></tr></tbody></table></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1&useformat=desktop" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Retrieved from "<a dir="ltr" href="https://en.wikipedia.org/w/index.php?title=Mladen_Vranic&oldid=1256330528">https://en.wikipedia.org/w/index.php?title=Mladen_Vranic&oldid=1256330528</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Help:Category" title="Help:Category">Categories</a>: <ul><li><a href="/wiki/Category:1930_births" title="Category:1930 births">1930 births</a></li><li><a href="/wiki/Category:2019_deaths" title="Category:2019 deaths">2019 deaths</a></li><li><a href="/wiki/Category:Canadian_diabetologists" title="Category:Canadian diabetologists">Canadian diabetologists</a></li><li><a href="/wiki/Category:Croatian_emigrants_to_Canada" title="Category:Croatian emigrants to Canada">Croatian emigrants to Canada</a></li><li><a href="/wiki/Category:Fellows_of_the_Royal_Society_of_Canada" title="Category:Fellows of the Royal Society of Canada">Fellows of the Royal Society of Canada</a></li><li><a href="/wiki/Category:Members_of_the_Order_of_Ontario" title="Category:Members of the Order of Ontario">Members of the Order of Ontario</a></li><li><a href="/wiki/Category:Officers_of_the_Order_of_Canada" title="Category:Officers of the Order of Canada">Officers of the Order of Canada</a></li><li><a href="/wiki/Category:Scientists_from_Toronto" title="Category:Scientists from Toronto">Scientists from Toronto</a></li><li><a href="/wiki/Category:Scientists_from_Zagreb" title="Category:Scientists from Zagreb">Scientists from Zagreb</a></li><li><a href="/wiki/Category:University_of_Zagreb_alumni" title="Category:University of Zagreb alumni">University of Zagreb alumni</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Hidden categories: <ul><li><a href="/wiki/Category:CS1_maint:_multiple_names:_authors_list" title="Category:CS1 maint: multiple names: authors list">CS1 maint: multiple names: authors list</a></li><li><a href="/wiki/Category:Articles_with_short_description" title="Category:Articles with short description">Articles with short description</a></li><li><a href="/wiki/Category:Short_description_matches_Wikidata" title="Category:Short description matches Wikidata">Short description matches Wikidata</a></li><li><a href="/wiki/Category:Autobiographical_articles_from_June_2017" title="Category:Autobiographical articles from June 2017">Autobiographical articles from June 2017</a></li><li><a href="/wiki/Category:Articles_lacking_reliable_references_from_June_2017" title="Category:Articles lacking reliable references from June 2017">Articles lacking reliable references from June 2017</a></li><li><a href="/wiki/Category:All_articles_lacking_reliable_references" title="Category:All articles lacking reliable references">All articles lacking reliable references</a></li><li><a href="/wiki/Category:Articles_with_multiple_maintenance_issues" title="Category:Articles with multiple maintenance issues">Articles with multiple maintenance issues</a></li><li><a href="/wiki/Category:Articles_with_hCards" title="Category:Articles with hCards">Articles with hCards</a></li><li><a href="/wiki/Category:Articles_containing_Croatian-language_text" title="Category:Articles containing Croatian-language text">Articles containing Croatian-language text</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> This page was last edited on 9 November 2024, at 11:31<span class="anonymous-show"> (UTC)</span>.</li> <li id="footer-info-copyright">Text is available under the <a href="/wiki/Wikipedia:Text_of_the_Creative_Commons_Attribution-ShareAlike_4.0_International_License" title="Wikipedia:Text of the Creative Commons Attribution-ShareAlike 4.0 International License">Creative Commons Attribution-ShareAlike 4.0 License</a>; additional terms may apply. By using this site, you agree to the <a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Terms_of_Use" class="extiw" title="foundation:Special:MyLanguage/Policy:Terms of Use">Terms of Use</a> and <a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy" class="extiw" title="foundation:Special:MyLanguage/Policy:Privacy policy">Privacy Policy</a>. Wikipedia® is a registered trademark of the <a rel="nofollow" class="external text" href="https://wikimediafoundation.org/">Wikimedia Foundation, Inc.</a>, a non-profit organization.</li> </ul> <ul id="footer-places"> <li id="footer-places-privacy"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Privacy_policy">Privacy policy</a></li> <li id="footer-places-about"><a href="/wiki/Wikipedia:About">About Wikipedia</a></li> <li id="footer-places-disclaimers"><a href="/wiki/Wikipedia:General_disclaimer">Disclaimers</a></li> <li id="footer-places-contact"><a href="//en.wikipedia.org/wiki/Wikipedia:Contact_us">Contact Wikipedia</a></li> <li id="footer-places-wm-codeofconduct"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Universal_Code_of_Conduct">Code of Conduct</a></li> <li id="footer-places-developers"><a href="https://developer.wikimedia.org">Developers</a></li> <li id="footer-places-statslink"><a href="https://stats.wikimedia.org/#/en.wikipedia.org">Statistics</a></li> <li id="footer-places-cookiestatement"><a href="https://foundation.wikimedia.org/wiki/Special:MyLanguage/Policy:Cookie_statement">Cookie statement</a></li> <li id="footer-places-mobileview"><a href="//en.m.wikipedia.org/w/index.php?title=Mladen_Vranic&mobileaction=toggle_view_mobile" class="noprint stopMobileRedirectToggle">Mobile view</a></li> </ul> <ul id="footer-icons" class="noprint"> <li id="footer-copyrightico"><a href="https://wikimediafoundation.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><img src="/static/images/footer/wikimedia-button.svg" width="84" height="29" alt="Wikimedia Foundation" loading="lazy"></a></li> <li id="footer-poweredbyico"><a href="https://www.mediawiki.org/" class="cdx-button cdx-button--fake-button cdx-button--size-large cdx-button--fake-button--enabled"><img src="/w/resources/assets/poweredby_mediawiki.svg" alt="Powered by MediaWiki" width="88" height="31" loading="lazy"></a></li> </ul> </footer> </div> </div> </div> <div class="vector-settings" id="p-dock-bottom"> <ul></ul> </div><script>(RLQ=window.RLQ||[]).push(function(){mw.config.set({"wgHostname":"mw-web.codfw.main-5f58cd8b6-s9j8g","wgBackendResponseTime":169,"wgPageParseReport":{"limitreport":{"cputime":"0.729","walltime":"0.855","ppvisitednodes":{"value":4211,"limit":1000000},"postexpandincludesize":{"value":194083,"limit":2097152},"templateargumentsize":{"value":9149,"limit":2097152},"expansiondepth":{"value":17,"limit":100},"expensivefunctioncount":{"value":3,"limit":500},"unstrip-depth":{"value":1,"limit":20},"unstrip-size":{"value":215014,"limit":5000000},"entityaccesscount":{"value":1,"limit":400},"timingprofile":["100.00% 753.521 1 -total"," 41.20% 310.487 1 Template:Reflist"," 25.81% 194.518 44 Template:Cite_journal"," 14.91% 112.354 1 Template:Infobox_person"," 12.82% 96.631 1 Template:Langx"," 9.54% 71.903 1 Template:Multiple_issues"," 9.10% 68.539 2 Template:Cite_web"," 8.69% 65.458 1 Template:Canadian_Medical_Hall_of_Fame"," 8.21% 61.889 1 Template:Navbox"," 7.42% 55.939 1 Template:Short_description"]},"scribunto":{"limitreport-timeusage":{"value":"0.502","limit":"10.000"},"limitreport-memusage":{"value":24142932,"limit":52428800}},"cachereport":{"origin":"mw-api-ext.codfw.main-6bd4c644cc-bpksh","timestamp":"20241203110735","ttl":2465551,"transientcontent":true}}});});</script> <script type="application/ld+json">{"@context":"https:\/\/schema.org","@type":"Article","name":"Mladen Vranic","url":"https:\/\/en.wikipedia.org\/wiki\/Mladen_Vranic","sameAs":"http:\/\/www.wikidata.org\/entity\/Q16091666","mainEntity":"http:\/\/www.wikidata.org\/entity\/Q16091666","author":{"@type":"Organization","name":"Contributors to Wikimedia projects"},"publisher":{"@type":"Organization","name":"Wikimedia Foundation, Inc.","logo":{"@type":"ImageObject","url":"https:\/\/www.wikimedia.org\/static\/images\/wmf-hor-googpub.png"}},"datePublished":"2014-01-10T17:24:42Z","dateModified":"2024-11-09T11:31:00Z","headline":"Canadian medical researcher"}</script> </body> </html>