Nature Reviews Urology

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In this Perspective, the authors present the available literature on metastatic non-muscle-invasive bladder cancer, and discuss the potential aetiologies underlying this condition.</p> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Michael Leyderman</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Thenappan Chandrasekar</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Hanan Goldberg</span></li> </ul> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">Perspective</span></span><time class="c-meta__item" datetime="2024-11-20" itemprop="datePublished">20 Nov 2024</time> </div> </div> </div> </article> </div> </li> <li class="app-reviews-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41585-024-00961-0/MediaObjects/41585_2024_961_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41585-024-00961-0/MediaObjects/41585_2024_961_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41585-024-00961-0/MediaObjects/41585_2024_961_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41585-024-00961-0" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Disruption of circadian rhythm as a potential pathogenesis of nocturia</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>The circadian rhythm has a crucial role in regulating nocturia. 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Damaser</span></li> </ul> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">Review Article</span></span><time class="c-meta__item" datetime="2024-11-14" itemprop="datePublished">14 Nov 2024</time> </div> </article> </div> </li> <li class="app-reviews-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41585-024-00962-z/MediaObjects/41585_2024_962_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41585-024-00962-z/MediaObjects/41585_2024_962_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41585-024-00962-z/MediaObjects/41585_2024_962_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41585-024-00962-z" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Molecular imaging of renal cell carcinomas: ready for prime time</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>In this Review, the authors provide an overview of molecular imaging in renal cell carcinoma, discussing the role of molecular imaging approaches in renal cell carcinoma diagnosis, treatment and response monitoring.</p> </div> </div> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Qianyun Wu</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Hongda Shao</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Weijun Wei</span></li> </ul> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">Review Article</span></span><time class="c-meta__item" datetime="2024-11-14" itemprop="datePublished">14 Nov 2024</time> </div> </article> </div> </li> <li class="app-reviews-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41585-024-00953-0/MediaObjects/41585_2024_953_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41585-024-00953-0/MediaObjects/41585_2024_953_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41585-024-00953-0/MediaObjects/41585_2024_953_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41585-024-00953-0" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link"><i>HSD3B1</i>, prostate cancer mortality and modifiable outcomes</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>A common germline missense-encoding polymorphism in <i>HSD3B1</i>, called the adrenal-permissive allele, facilitates androgen synthesis from adrenal precursors via increased 3β-hydroxysteroid dehydrogenase 1 (3βHSD1). Here, the authors focus on mechanistic and clinical investigations of 3βHSD1 and the clinical consequences and potential utility of detecting adrenal-permissive allele inheritance.</p> </div> </div> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Pedro F. S. Freitas</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Alireza Abdshah</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Nima Sharifi</span></li> </ul> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">Perspective</span></span><time class="c-meta__item" datetime="2024-11-14" itemprop="datePublished">14 Nov 2024</time> </div> </article> </div> </li> <li class="app-reviews-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs41585-024-00952-1/MediaObjects/41585_2024_952_Fig1_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41585-024-00952-1/MediaObjects/41585_2024_952_Fig1_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs41585-024-00952-1/MediaObjects/41585_2024_952_Fig1_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41585-024-00952-1" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Exploring the impact of lipid stress on sperm cytoskeleton: insights and prospects</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>High-fat diets disrupt testicular function by accumulating lipids, impairing sperm production and affecting the cytoskeleton of spermatogenic cells. This Perspective aims to understand these mechanisms to develop treatments for infertility in men with obesity.</p> </div> </div> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Tania E. Saez Lancellotti</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">María V. Avena</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Miguel W. Fornes</span></li> </ul> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">Perspective</span></span><time class="c-meta__item" datetime="2024-11-11" itemprop="datePublished">11 Nov 2024</time> </div> </article> </div> </li> </ul> </li> <li> <ul class="app-reviews-row__side"> <li class="app-reviews-row__side-item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41585-024-00951-2" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Pre-treatment metastatic biopsy: a step towards precision oncology for urothelial cancer</a> </h3> </div> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Niklas Klümper</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Alexander Cox</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Markus Eckstein</span></li> </ul> </div> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">Review Article</span></span><time class="c-meta__item" datetime="2024-10-29" itemprop="datePublished">29 Oct 2024</time> </div> </article> </div> </li> <li class="app-reviews-row__side-item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s41585-024-00948-x" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Racial disparities in prostate cancer in the UK and the USA: similarities, differences and steps forwards</a> </h3> </div> </div> <div class="c-card__section c-meta"> <div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Edward Christopher Dee</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Rebecca Todd</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Paul L. 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