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From Data to Practice: Assessing New Alzheimer's Disease Therapies

<html lang="en"> <head> <!-- CookiePro Cookies Consent Notice start for neuronline.sfn.org --> <script type="text/javascript" src="https://cookie-cdn.cookiepro.com/consent/"760f75b9-29b1-4959-abf2-900a95e073e4"/OtAutoBlock.js"></script> <script src="https://cookie-cdn.cookiepro.com/scripttemplates/otSDKStub.js" type="text/javascript" charset="UTF-8" data-domain-script="760f75b9-29b1-4959-abf2-900a95e073e4"></script> <script type="text/javascript"> function OptanonWrapper() { } </script> <!-- CookiePro Cookies Consent Notice end for neuronline.sfn.org --> <meta charset="utf-8"> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <meta name="viewport" content="width=device-width, initial-scale=1"> <link rel="stylesheet" href="https://fonts.googleapis.com/css?family=Roboto:300,400,700|Open+Sans:400,700"> <title>From Data to Practice: Assessing New Alzheimer&#39;s Disease Therapies</title> <meta name="pageID" content="34bc9616-7413-44f3-bec9-4d2b0db132d6&fo=34bc9616-7413-44f3-bec9-4d2b0db132d6"> <meta name="description" content="&lt;p&gt;Karl Herrup, Michelle Jin, and James Noble share their perspectives on evaluating the clinical impacts of emerging treatments for Alzheimer&amp;rsquo;s Disease. 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<h1 class="article-title">From Data to Practice: Assessing New Alzheimer&#39;s Disease Therapies</h1> <div class="article-navigation"> <ul class="nav nav-pills justify-content-center" role="tablist"> <li class="nav-item"> <a class="nav-link active" id="A_0f308075c6024526bf90852e0445eed8-tab" data-toggle="tab" role="tab" href="#A_0f308075c6024526bf90852e0445eed8">Overview</a> </li> <li class="nav-item"> <a class="nav-link " id="A_6a01f60789bb482d8eb2edc04da1c91d-tab" data-toggle="tab" role="tab" href="#A_6a01f60789bb482d8eb2edc04da1c91d">Speakers</a> </li> <li class="nav-item"> <a class="nav-link " id="A_6a60a6e1357d4f7e80b90ff44b53adbf-tab" data-toggle="tab" role="tab" href="#A_6a60a6e1357d4f7e80b90ff44b53adbf">FAQs</a> </li> <li class="nav-item"> <a class="nav-link " id="A_b940816f4fe84b458a9b7881cfcd8712-tab" data-toggle="tab" role="tab" href="#A_b940816f4fe84b458a9b7881cfcd8712">Event Policies</a> </li> <li class="nav-item"> <a class="nav-link " 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src="//s7.addthis.com/js/300/addthis_widget.js#pubid=ra-53d937761c013c09"></script> <!-- Begin Body --> <div class="tab-content" id=""> <div class="tab-pane fade show active" id="A_0f308075c6024526bf90852e0445eed8" aria-labelledby="A_0f308075c6024526bf90852e0445eed8-tab"> <p>Karl Herrup, Michelle Jin, and James Noble share their perspectives on evaluating the clinical impacts of emerging treatments for Alzheimer&rsquo;s Disease. Attendees can submit questions at registration and live during the webinar.</p> <p>Read two Commentaries informing this discussion:</p> <ul> <li><a rel="noopener noreferrer" href="https://www.eneuro.org/content/11/7/ENEURO.0319-23.2024" target="_blank">Lecanemab and Donanemab as Therapies for Alzheimer's Disease: An Illustrated Perspective on the Data</a> by Alberto J. Espay, Kasper P. Keep, and Karl Herrup</li> <li><a rel="noopener noreferrer" href="https://www.eneuro.org/content/11/9/ENEURO.0088-24.2024" target="_blank">What's in It for Me? Contextualizing the Potential Clinical Impacts of Lecanemab, Donanemab, and Other Anti-&beta;-amyloid Monoclonal Antibodies in Early Alzheimer's Disease</a> by Michelle Jin and James M. Noble</li> </ul> </div> <div class="tab-pane fade " id="A_6a01f60789bb482d8eb2edc04da1c91d" aria-labelledby="A_6a01f60789bb482d8eb2edc04da1c91d-tab"> <div class="article-speakers"> <h3>Speakers</h3> <div class="speaker-item"> <div class="image"> <img src="https://neuronline.sfn.org/-/media/Project/Neuronline/Bio-Images/Rectangle/2022/20220127_Karl-Herrup.jpg?h=150&amp;w=120&amp;la=en&amp;hash=D7F38574135C102F991E239398D88B8ACB84D9AD" alt="Image of Karl Herrup, PhD." /> </div> <div class="content"> <div class="name"> Karl Herrup, PhD </div> <div class="biography"> Karl Herrup is a professor of neurobiology at the University of Pittsburgh School of Medicine. Herrup previously served as the director of the Alzheimer's Research Center at Case Western Reserve University and the chair of cell biology and neuroscience at Rutgers University. His main research interests lie in the cell biology of neurodegenerative disease, with a focus on Alzheimer's disease. He received his PhD in neurobiology from Stanford University. He completed his postdoctoral training at Harvard Medical School and the Biozentrum in Basel Switzerland. </div> </div> </div> <div class="speaker-item"> <div class="image"> <img src="https://neuronline.sfn.org/-/media/Project/Neuronline/Webinar-Images/Speakers/2024/james-noble-120.jpg?h=150&amp;w=120&amp;la=en&amp;hash=F77E0B6A783CFF887E720BB50946A6CA2EFF4C11" alt="James Noble" /> </div> <div class="content"> <div class="name"> James Noble, MD, MS, CPH, FAAN </div> <div class="biography"> James Noble is an associate professor of neurology in the Taub Institute for Research on Alzheimer’s Disease and the Aging Brain at Columbia University Irving Medical Center (CUIMC). His clinical, research, outreach, advocacy, and education efforts are focused on modifiable risk factors of cognitive aging and improving awareness of neurological disorders. Noble is the clinical core leader of the Alzheimer’s Disease Research Center and directs several large programs funded by the National Institute of Aging. He sees patients in the CUIMC Aging & Dementia clinical practice where he also serves as a project lead in the Columbia CMS-GUIDE program. Additionally, he is co-editor of the standard text Merritt’s Neurology (Wolters-Kluwer 2021), the author of the caregiver handbook Navigating Life with Dementia (Oxford University Press/American Academy of Neurology 2022), and co-founder of Arts & Minds, a non-profit organization which provides art-centered museum based programs to persons with dementia and their care partners. </div> </div> </div> <div class="speaker-item"> <div class="image"> <img src="https://neuronline.sfn.org/-/media/Project/Neuronline/Webinar-Images/Speakers/2024/michelle-jin-120.jpg?h=150&amp;w=120&amp;la=en&amp;hash=AE3E280BAD9A1E7B6ABFC56F874C5B9D2037B8C5" alt="Michelle Jin" /> </div> <div class="content"> <div class="name"> Michelle Jin, MS </div> <div class="biography"> Michelle Jin is an MD/PhD candidate enrolled in the Medical Scientist Training Program at Columbia University, Vagelos College of Physicians and Surgeons. Her doctoral research focuses on a comprehensive mapping of the behavioral and neural changes underlying sleep-wake disorders in an Alzheimer’s disease mouse model, as well as developing accessible methods for mapping and analysis of brain-wide activity in mice. Her work is supported by a predoctoral Ruth L. Kirschstein National Research Service Award from the National Institute on Aging. She earned her BA in biology and psychology from Cornell University in 2017 and previously receive a postbaccalaureate intramural research training fellowship to conduct research at the National Institute on Drug Abuse from 2017-2019. </div> </div> </div> <div class="speaker-item"> <div class="image"> <img src="https://neuronline.sfn.org/-/media/Project/Neuronline/Bio-Images/Rectangle/Christophe-Bernard.jpg?h=150&amp;w=120&amp;la=en&amp;hash=BDC61EB3DEDBE3A5DBB4228914CC19AC2BAF3E45" alt="Christophe Bernard" /> </div> <div class="content"> <div class="name"> Christophe Bernard, PhD </div> <div class="biography"> Christophe Bernard, PhD, is the PhysioNet team leader in at the Institute of Neuroscience Systems at the French Institute of Health and Medical Research (INSERM). His research focuses on understanding how physiological and pathological behaviors emerge from the organization and reorganization of the underlying neuronal architecture, with an emphasis on epilepsy. He currently serves as editor-in-chief of <em>eNeuro</em>. </div> </div> </div> </div> </div> <div class="tab-pane fade " id="A_6a60a6e1357d4f7e80b90ff44b53adbf" aria-labelledby="A_6a60a6e1357d4f7e80b90ff44b53adbf-tab"> <p><strong>Who can attend these webinars?</strong> All webinars in this series are complimentary to SfN members. <a href="https://my.sfn.org/Membership/Join">Join</a> or <a href="https://www.sfn.org/membership/renew-individual-membership">renew</a> for access. This webinar is $15 for nonmembers.</p> <p><strong>Will the webinars be available on-demand? </strong> Yes, all webinars will be available to watch on demand after the live broadcast.</p> <p><strong>How do I access the conference on the live day?</strong> After registering, you will receive a confirmation email with the event link and the option to download calendar reminders.</p> <p><strong>What are the technology requirements for attending?&nbsp;</strong><span>These webinars are hosted on Zoom Webinar. Instructions for joining and participating in a webinar can be found&nbsp;</span><a rel="noopener noreferrer" href="https://support.zoom.us/hc/en-us/articles/115004954946-Joining-and-participating-in-a-webinar-attendee-" target="_blank">here</a><span>.</span></p> <p><span><strong>Can I ask the presenters questions?</strong>&nbsp;Yes! You can submit any questions before the webinar through the registration form. During the webinar, you can submit questions through the Q&amp;A box.</span></p> <p><strong>Will a certificate of attendance be offered for this event?</strong> No, SfN does not provide certificates of attendance for webinars.&nbsp;</p> <p><strong>I have other questions not answered here.</strong> Email <a href="mailto:digitallearning@sfn.org">digitallearning@sfn.org</a>&nbsp;with any other questions.&nbsp;</p> </div> <div class="tab-pane fade " id="A_b940816f4fe84b458a9b7881cfcd8712" aria-labelledby="A_b940816f4fe84b458a9b7881cfcd8712-tab"> <p>Review <a href="https://www.sfn.org/about/professional-conduct/code-of-conduct-at-sfn-events">SfN&rsquo;s Code of Conduct</a>, rules for virtual events in the <a href="https://neuronline.sfn.org/community-guidelines">Digital Learning Community Guidelines</a>, and communications policies regarding dissemination of unpublished scientific data, listed below. SfN asks that conference attendees respect the sensitivity of information and data being presented that are not yet available to the public by following these guidelines:</p> <ul> <li>Do not capture or publicly share details of any unpublished data presented.</li> <li>If you are unsure whether data is unpublished, check with the presenter.</li> <li>Respect presenters' wishes if they indicate that the information presented is not to be shared. </li> </ul> <h3>Webinar Refund Policy</h3> <p><strong>What is the cancellation/refund policy for webinars?</strong></p> <ul> <li>If SfN changes fundamental details of the webinar (date, time, or speakers), nonmember registrants may request a registration refund.</li> <li>To request a refund, please email <a href="mailto:digitallearning@sfn.org">digitallearning@sfn.org</a> at least 48 hours before the event. Otherwise, refunds are not provided. 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