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class="work-thumbnail" src="https://attachments.academia-assets.com/117980013/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/123581106/New_Horizons_in_Regenerative_Medicine_in_Organ_Repair">New Horizons in Regenerative Medicine in Organ Repair</a></div><div class="wp-workCard_item"><span>InTech eBooks</span><span>, May 2, 2018</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="91f44b063afeccfdd4985ec54c581c27" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":117980013,"asset_id":123581106,"asset_type":"Work","button_location":"profile"}" 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href="https://www.academia.edu/123581105/Tissue_Engineering_Current_Status_and_amp_Futuristic_Scope"><img alt="Research paper thumbnail of Tissue Engineering; Current Status &amp; Futuristic Scope" class="work-thumbnail" src="https://attachments.academia-assets.com/117979997/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/123581105/Tissue_Engineering_Current_Status_and_amp_Futuristic_Scope">Tissue Engineering; Current Status &amp; Futuristic Scope</a></div><div class="wp-workCard_item"><span>Journal of medicine and life</span><span>, Jul 1, 2019</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="3f8b641545a4fce58068895bc3a00c58" class="wp-workCard--action" rel="nofollow" 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/></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/104431504/Futuristic_Scope_of_Stem_Cells_in_Medicine">Futuristic Scope of Stem Cells in Medicine</a></div><div class="wp-workCard_item"><span>Asian Journal of Pharmaceutical and Clinical Research</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The most potential application of the stem cells (SCs) in human beings lies in their ability to r...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The most potential application of the stem cells (SCs) in human beings lies in their ability to regenerate cells and tissues. They differentiate themselves into specific cell type, thereby availing remarkable source of replacement cells and tissues. They differentiate themselves into specific cell types, thereby availing renewable source of replacement cells and tissues. Their potential of regeneration has now opened many avenues in the field of medical science and research. As a therapeutic adjuvant in near future, the SCs will emerge as an efficient technique to completely heal a number of diseases including diabetes, heart diseases and strokes, osteoarthritis, rheumatoid arthritis, and macular degeneration. The researches, which are underway, some of them will surely be proved as safe and effective SC treatment in the market in due course of time. 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Keywords: Stem cells, Medicine, Embryonic cells, Heart disease.","publication_date":{"day":null,"month":null,"year":2016,"errors":{}},"publication_name":"Asian Journal of Pharmaceutical and Clinical Research"},"translated_abstract":"The most potential application of the stem cells (SCs) in human beings lies in their ability to regenerate cells and tissues. They differentiate themselves into specific cell type, thereby availing remarkable source of replacement cells and tissues. They differentiate themselves into specific cell types, thereby availing renewable source of replacement cells and tissues. Their potential of regeneration has now opened many avenues in the field of medical science and research. As a therapeutic adjuvant in near future, the SCs will emerge as an efficient technique to completely heal a number of diseases including diabetes, heart diseases and strokes, osteoarthritis, rheumatoid arthritis, and macular degeneration. The researches, which are underway, some of them will surely be proved as safe and effective SC treatment in the market in due course of time. Keywords: Stem cells, Medicine, Embryonic cells, Heart disease.","internal_url":"https://www.academia.edu/104431504/Futuristic_Scope_of_Stem_Cells_in_Medicine","translated_internal_url":"","created_at":"2023-07-10T08:05:28.110-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":172202773,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Futuristic_Scope_of_Stem_Cells_in_Medicine","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":172202773,"first_name":"Paramjit","middle_initials":null,"last_name":"Dhot","page_name":"PDhot","domain_name":"independent","created_at":"2020-09-28T17:10:23.981-07:00","display_name":"Paramjit Dhot","url":"https://independent.academia.edu/PDhot"},"attachments":[],"research_interests":[{"id":12733,"name":"Rheumatoid Arthritis","url":"https://www.academia.edu/Documents/in/Rheumatoid_Arthritis"},{"id":23163,"name":"Stem Cell","url":"https://www.academia.edu/Documents/in/Stem_Cell"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":106582,"name":"Embryonic Stem Cell","url":"https://www.academia.edu/Documents/in/Embryonic_Stem_Cell"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="104431503"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/104431503/Scope_of_Gas_Chromatography_Mass_Spectrometry_in_Inborn_Errors_of_Metabolism_Screening_A_Review"><img alt="Research paper thumbnail of Scope of Gas Chromatography-Mass Spectrometry in Inborn Errors of Metabolism Screening: A Review" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/104431503/Scope_of_Gas_Chromatography_Mass_Spectrometry_in_Inborn_Errors_of_Metabolism_Screening_A_Review">Scope of Gas Chromatography-Mass Spectrometry in Inborn Errors of Metabolism Screening: A Review</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Inborn errors of metabolism (IEM) arise from inherited errors in enzyme in any of the metabolic p...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Inborn errors of metabolism (IEM) arise from inherited errors in enzyme in any of the metabolic pathways. Symptoms are developed due to the accumulation of biosynthetic precursors or product that baby cannot excrete. IEM screening is a field that is undergoing a revolutionary change in its all aspects. Technological advances are transforming the way in which we can diagnose the whole population of IEM. In last few decades, evolution of gas chromatography-mass spectrometry (GC-MS) has improved our diagnostic capabilities in many fields. It is now possible to screen rapidly, simultaneously and inexpensively for a number of very rare disorders using GC-MS. Recent developments in the field of analytical and separation science and MS has brought about great improvement in GC-MS efficiency and sensitivity. The use of this technique in newborn screening made it possible in the present scenario, to screen for a wide range of previously unscreened IEM, including aminoacidemias, fatty acid ox...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104431503"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104431503"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104431503; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104431503]").text(description); $(".js-view-count[data-work-id=104431503]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104431503; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104431503']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104431503, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=104431503]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104431503,"title":"Scope of Gas Chromatography-Mass Spectrometry in Inborn Errors of Metabolism Screening: A Review","translated_title":"","metadata":{"abstract":"Inborn errors of metabolism (IEM) arise from inherited errors in enzyme in any of the metabolic pathways. Symptoms are developed due to the accumulation of biosynthetic precursors or product that baby cannot excrete. IEM screening is a field that is undergoing a revolutionary change in its all aspects. Technological advances are transforming the way in which we can diagnose the whole population of IEM. In last few decades, evolution of gas chromatography-mass spectrometry (GC-MS) has improved our diagnostic capabilities in many fields. It is now possible to screen rapidly, simultaneously and inexpensively for a number of very rare disorders using GC-MS. Recent developments in the field of analytical and separation science and MS has brought about great improvement in GC-MS efficiency and sensitivity. The use of this technique in newborn screening made it possible in the present scenario, to screen for a wide range of previously unscreened IEM, including aminoacidemias, fatty acid ox...","publication_date":{"day":null,"month":null,"year":2015,"errors":{}}},"translated_abstract":"Inborn errors of metabolism (IEM) arise from inherited errors in enzyme in any of the metabolic pathways. Symptoms are developed due to the accumulation of biosynthetic precursors or product that baby cannot excrete. IEM screening is a field that is undergoing a revolutionary change in its all aspects. Technological advances are transforming the way in which we can diagnose the whole population of IEM. In last few decades, evolution of gas chromatography-mass spectrometry (GC-MS) has improved our diagnostic capabilities in many fields. It is now possible to screen rapidly, simultaneously and inexpensively for a number of very rare disorders using GC-MS. Recent developments in the field of analytical and separation science and MS has brought about great improvement in GC-MS efficiency and sensitivity. The use of this technique in newborn screening made it possible in the present scenario, to screen for a wide range of previously unscreened IEM, including aminoacidemias, fatty acid ox...","internal_url":"https://www.academia.edu/104431503/Scope_of_Gas_Chromatography_Mass_Spectrometry_in_Inborn_Errors_of_Metabolism_Screening_A_Review","translated_internal_url":"","created_at":"2023-07-10T08:05:27.976-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":172202773,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Scope_of_Gas_Chromatography_Mass_Spectrometry_in_Inborn_Errors_of_Metabolism_Screening_A_Review","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":172202773,"first_name":"Paramjit","middle_initials":null,"last_name":"Dhot","page_name":"PDhot","domain_name":"independent","created_at":"2020-09-28T17:10:23.981-07:00","display_name":"Paramjit Dhot","url":"https://independent.academia.edu/PDhot"},"attachments":[],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64336,"name":"Population","url":"https://www.academia.edu/Documents/in/Population"},{"id":197938,"name":"Newborn Screening","url":"https://www.academia.edu/Documents/in/Newborn_Screening"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="104431502"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/104431502/Yoga_Practice_and_Biochemical_and_Physiological_Alterations_in_Normal_Subjects"><img alt="Research paper thumbnail of Yoga Practice and Biochemical and Physiological Alterations in Normal Subjects" class="work-thumbnail" src="https://attachments.academia-assets.com/104163539/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/104431502/Yoga_Practice_and_Biochemical_and_Physiological_Alterations_in_Normal_Subjects">Yoga Practice and Biochemical and Physiological Alterations in Normal Subjects</a></div><div class="wp-workCard_item"><span>Asian Journal of Pharmaceutical and Clinical Research</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Objective: To assess the effect of 45 minute yogic kriya (Surya Namaskar and Kapalbhati) for 30 d...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Objective: To assess the effect of 45 minute yogic kriya (Surya Namaskar and Kapalbhati) for 30 days on various physiological and biochemical parameters. Methods: About 20 Nursing College students of the Santosh Medical University, Ghaziabad, between the age group 17 and 21 years volunteered to participate in the study. They were divided into two Groups A and B. Group A students including 10 students in each group were subjected to 30 days yoge kriya for 45 minutes for 6 days in a week. Statistical analysis: A student’s t-test was used for comparing the means of pre- and post-yoga results of various parameters. Results: No significant difference was found in systolic blood pressure, pulse, body mass index, hemoglobin except for fasting blood sugar and diastolic blood pressure (p&lt;0.001) among the yoga subject while comparing with baseline values and control. Keywords: Yoga, Biochemical alterations, Physiological alterations, Surya Namaskar and Kapal Bhati.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5931cd286242ddf7d2e73a3363d9ac80" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":104163539,"asset_id":104431502,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/104163539/download_file?st=MTczMjQ2NzMyMiw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104431502"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104431502"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104431502; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104431502]").text(description); $(".js-view-count[data-work-id=104431502]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104431502; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104431502']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104431502, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "5931cd286242ddf7d2e73a3363d9ac80" } } $('.js-work-strip[data-work-id=104431502]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104431502,"title":"Yoga Practice and Biochemical and Physiological Alterations in Normal Subjects","translated_title":"","metadata":{"abstract":"Objective: To assess the effect of 45 minute yogic kriya (Surya Namaskar and Kapalbhati) for 30 days on various physiological and biochemical parameters. Methods: About 20 Nursing College students of the Santosh Medical University, Ghaziabad, between the age group 17 and 21 years volunteered to participate in the study. They were divided into two Groups A and B. Group A students including 10 students in each group were subjected to 30 days yoge kriya for 45 minutes for 6 days in a week. Statistical analysis: A student’s t-test was used for comparing the means of pre- and post-yoga results of various parameters. Results: No significant difference was found in systolic blood pressure, pulse, body mass index, hemoglobin except for fasting blood sugar and diastolic blood pressure (p\u0026lt;0.001) among the yoga subject while comparing with baseline values and control. Keywords: Yoga, Biochemical alterations, Physiological alterations, Surya Namaskar and Kapal Bhati.","publication_date":{"day":null,"month":null,"year":2016,"errors":{}},"publication_name":"Asian Journal of Pharmaceutical and Clinical Research"},"translated_abstract":"Objective: To assess the effect of 45 minute yogic kriya (Surya Namaskar and Kapalbhati) for 30 days on various physiological and biochemical parameters. Methods: About 20 Nursing College students of the Santosh Medical University, Ghaziabad, between the age group 17 and 21 years volunteered to participate in the study. They were divided into two Groups A and B. Group A students including 10 students in each group were subjected to 30 days yoge kriya for 45 minutes for 6 days in a week. Statistical analysis: A student’s t-test was used for comparing the means of pre- and post-yoga results of various parameters. Results: No significant difference was found in systolic blood pressure, pulse, body mass index, hemoglobin except for fasting blood sugar and diastolic blood pressure (p\u0026lt;0.001) among the yoga subject while comparing with baseline values and control. Keywords: Yoga, Biochemical alterations, Physiological alterations, Surya Namaskar and Kapal 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Although their ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Platelet function disorders are a fairly common cause of bleeding manifestations. Although their relative types and incidence are well documented, data from India are lacking. Between 1970 and 1991, we studied the clinical and laboratory features of 144 north Indian patients who presented to our hospital with a bleeding diathesis in whom coagulation disorders, von Willebrand&#39;s disease and a history of drug ingestion were absent. Isolated platelet factor 3 availability defect was the commonest (56 cases) followed by the thrombasthenias (49 cases), arachidonic acid pathway defect (26 cases), storage pool disease (8 cases) and the Bernard-Soulier syndrome (3 cases). Isolated platelet factor 3 deficiency was rare (2 cases). Two varieties of thrombasthenia were seen--the classical Glanzmann&#39;s (13 cases) and thrombopathic (36 cases). The latter was characterized by absent or sub-normal platelet aggregation with agonists along with a reduced (to less than 50% of normal) total plate...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104431499"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104431499"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104431499; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104431499]").text(description); $(".js-view-count[data-work-id=104431499]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104431499; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104431499']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104431499, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=104431499]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104431499,"title":"Platelet function disorders in north India","translated_title":"","metadata":{"abstract":"Platelet function disorders are a fairly common cause of bleeding manifestations. 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The latter was characterized by absent or sub-normal platelet aggregation with agonists along with a reduced (to less than 50% of normal) total plate...","publication_name":"The National medical journal of India"},"translated_abstract":"Platelet function disorders are a fairly common cause of bleeding manifestations. Although their relative types and incidence are well documented, data from India are lacking. Between 1970 and 1991, we studied the clinical and laboratory features of 144 north Indian patients who presented to our hospital with a bleeding diathesis in whom coagulation disorders, von Willebrand\u0026#39;s disease and a history of drug ingestion were absent. Isolated platelet factor 3 availability defect was the commonest (56 cases) followed by the thrombasthenias (49 cases), arachidonic acid pathway defect (26 cases), storage pool disease (8 cases) and the Bernard-Soulier syndrome (3 cases). Isolated platelet factor 3 deficiency was rare (2 cases). Two varieties of thrombasthenia were seen--the classical Glanzmann\u0026#39;s (13 cases) and thrombopathic (36 cases). The latter was characterized by absent or sub-normal platelet aggregation with agonists along with a reduced (to less than 50% of normal) total plate...","internal_url":"https://www.academia.edu/104431499/Platelet_function_disorders_in_north_India","translated_internal_url":"","created_at":"2023-07-10T08:05:27.118-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":172202773,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Platelet_function_disorders_in_north_India","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":172202773,"first_name":"Paramjit","middle_initials":null,"last_name":"Dhot","page_name":"PDhot","domain_name":"independent","created_at":"2020-09-28T17:10:23.981-07:00","display_name":"Paramjit Dhot","url":"https://independent.academia.edu/PDhot"},"attachments":[],"research_interests":[{"id":5500,"name":"Incidence Geometry","url":"https://www.academia.edu/Documents/in/Incidence_Geometry"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":43838,"name":"India","url":"https://www.academia.edu/Documents/in/India"},{"id":52136,"name":"Platelet","url":"https://www.academia.edu/Documents/in/Platelet"},{"id":58185,"name":"Medical tourism india","url":"https://www.academia.edu/Documents/in/Medical_tourism_india"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="104431498"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/104431498/Acquired_deficiency_of_factor_XIII"><img alt="Research paper thumbnail of Acquired deficiency of factor XIII" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/104431498/Acquired_deficiency_of_factor_XIII">Acquired deficiency of factor XIII</a></div><div class="wp-workCard_item"><span>The Journal of the Association of Physicians of India</span><span>, 1994</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104431498"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104431498"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104431498; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104431498]").text(description); $(".js-view-count[data-work-id=104431498]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104431498; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104431498']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104431498, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=104431498]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104431498,"title":"Acquired deficiency of factor XIII","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":1994,"errors":{}},"publication_name":"The Journal of the Association of Physicians of India"},"translated_abstract":null,"internal_url":"https://www.academia.edu/104431498/Acquired_deficiency_of_factor_XIII","translated_internal_url":"","created_at":"2023-07-10T08:05:26.966-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":172202773,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Acquired_deficiency_of_factor_XIII","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":172202773,"first_name":"Paramjit","middle_initials":null,"last_name":"Dhot","page_name":"PDhot","domain_name":"independent","created_at":"2020-09-28T17:10:23.981-07:00","display_name":"Paramjit Dhot","url":"https://independent.academia.edu/PDhot"},"attachments":[],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":1518796,"name":"Leiomyoma","url":"https://www.academia.edu/Documents/in/Leiomyoma"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="104431497"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/104431497/Normal_values_of_CD4_and_CD8_lymphocyte_subsets_in_healthy_indian_adults_and_the_effects_of_sex_age_ethnicity_and_smoking"><img alt="Research paper thumbnail of Normal values of CD4 and CD8 lymphocyte subsets in healthy indian adults and the effects of sex, age, ethnicity, and smoking" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/104431497/Normal_values_of_CD4_and_CD8_lymphocyte_subsets_in_healthy_indian_adults_and_the_effects_of_sex_age_ethnicity_and_smoking">Normal values of CD4 and CD8 lymphocyte subsets in healthy indian adults and the effects of sex, age, ethnicity, and smoking</a></div><div class="wp-workCard_item"><span>Cytometry</span><span>, 2003</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Information on lymphocyte populations (T, B, and natural killer cells) and subpopulations (CD4 an...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Information on lymphocyte populations (T, B, and natural killer cells) and subpopulations (CD4 and CD8) in India is generally lacking. Measurement of T-cell subsets is important in India for evaluating disease stage and progression in individuals with the human immunodeficiency virus (HIV). Hence, this study was conducted to provide normal ranges of absolute and percentage values of CD4 and CD8 T-lymphocyte subsets and the ratio of CD4 to CD8 in normal Indian adults. Flow cytometric analysis (EPICS-XL) was used to determine the range of T-lymphocyte subpopulations in normal Indian blood donors at Command Hospital and the Armed Forces Medical College, Pune, India. The reference population consisted of 94 healthy HIV-seronegative blood donors. T-lymphocyte subsets were analyzed with two-color immunophenotyping of peripheral blood lymphocytes with the use of a lysed whole-blood technique and enumerated. For normal values of various blood components, we found mean values of 2114 cells/microl for total lymphocytes, 865 cells/microl (40.2%) for CD4(+) lymphocytes, 552 cells/microl (31.3%) for CD8(+) lymphocytes, and 1.7 for the CD4:CD8 ratio. The 95% confidence intervals for the same parameters were 1115-4009 cells/microl, 430-1740 cells/microl (30.75-49.60%), 218-1396 cells/microl (20.06-42.52%), and 0.39-3.02 respectively. Females had significantly higher CD4 counts (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05), percentage of CD4 lymphocytes (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01), and CD4:CD8 ratio (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Males had a significantly higher percentage of CD8 lymphocytes (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). They also had higher CD8 counts that did not reach significance. Age, ethnicity (Dravidian versus Aryan), smoking, alcohol consumption, and the interval between drawing the blood sample and its analysis were factors that did not produce statistically significant differences in the T-cell subsets studied. When compared with other published series, the CD4 and CD8 values in healthy Indians were no different from those reported in the West. These observations have important clinical implications for the use of T-lymphocyte subset measurements in India, especially in the management of HIV infection. The normal ranges established by this study can be used as a reference for decisions made in clinical practice.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104431497"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104431497"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104431497; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104431497]").text(description); $(".js-view-count[data-work-id=104431497]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104431497; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104431497']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104431497, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=104431497]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104431497,"title":"Normal values of CD4 and CD8 lymphocyte subsets in healthy indian adults and the effects of sex, age, ethnicity, and smoking","translated_title":"","metadata":{"abstract":"Information on lymphocyte populations (T, B, and natural killer cells) and subpopulations (CD4 and CD8) in India is generally lacking. Measurement of T-cell subsets is important in India for evaluating disease stage and progression in individuals with the human immunodeficiency virus (HIV). Hence, this study was conducted to provide normal ranges of absolute and percentage values of CD4 and CD8 T-lymphocyte subsets and the ratio of CD4 to CD8 in normal Indian adults. Flow cytometric analysis (EPICS-XL) was used to determine the range of T-lymphocyte subpopulations in normal Indian blood donors at Command Hospital and the Armed Forces Medical College, Pune, India. The reference population consisted of 94 healthy HIV-seronegative blood donors. T-lymphocyte subsets were analyzed with two-color immunophenotyping of peripheral blood lymphocytes with the use of a lysed whole-blood technique and enumerated. For normal values of various blood components, we found mean values of 2114 cells/microl for total lymphocytes, 865 cells/microl (40.2%) for CD4(+) lymphocytes, 552 cells/microl (31.3%) for CD8(+) lymphocytes, and 1.7 for the CD4:CD8 ratio. The 95% confidence intervals for the same parameters were 1115-4009 cells/microl, 430-1740 cells/microl (30.75-49.60%), 218-1396 cells/microl (20.06-42.52%), and 0.39-3.02 respectively. Females had significantly higher CD4 counts (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05), percentage of CD4 lymphocytes (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01), and CD4:CD8 ratio (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Males had a significantly higher percentage of CD8 lymphocytes (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). They also had higher CD8 counts that did not reach significance. Age, ethnicity (Dravidian versus Aryan), smoking, alcohol consumption, and the interval between drawing the blood sample and its analysis were factors that did not produce statistically significant differences in the T-cell subsets studied. When compared with other published series, the CD4 and CD8 values in healthy Indians were no different from those reported in the West. These observations have important clinical implications for the use of T-lymphocyte subset measurements in India, especially in the management of HIV infection. The normal ranges established by this study can be used as a reference for decisions made in clinical practice.","publisher":"Wiley","publication_date":{"day":null,"month":null,"year":2003,"errors":{}},"publication_name":"Cytometry"},"translated_abstract":"Information on lymphocyte populations (T, B, and natural killer cells) and subpopulations (CD4 and CD8) in India is generally lacking. Measurement of T-cell subsets is important in India for evaluating disease stage and progression in individuals with the human immunodeficiency virus (HIV). Hence, this study was conducted to provide normal ranges of absolute and percentage values of CD4 and CD8 T-lymphocyte subsets and the ratio of CD4 to CD8 in normal Indian adults. Flow cytometric analysis (EPICS-XL) was used to determine the range of T-lymphocyte subpopulations in normal Indian blood donors at Command Hospital and the Armed Forces Medical College, Pune, India. The reference population consisted of 94 healthy HIV-seronegative blood donors. T-lymphocyte subsets were analyzed with two-color immunophenotyping of peripheral blood lymphocytes with the use of a lysed whole-blood technique and enumerated. For normal values of various blood components, we found mean values of 2114 cells/microl for total lymphocytes, 865 cells/microl (40.2%) for CD4(+) lymphocytes, 552 cells/microl (31.3%) for CD8(+) lymphocytes, and 1.7 for the CD4:CD8 ratio. The 95% confidence intervals for the same parameters were 1115-4009 cells/microl, 430-1740 cells/microl (30.75-49.60%), 218-1396 cells/microl (20.06-42.52%), and 0.39-3.02 respectively. Females had significantly higher CD4 counts (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05), percentage of CD4 lymphocytes (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01), and CD4:CD8 ratio (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Males had a significantly higher percentage of CD8 lymphocytes (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). They also had higher CD8 counts that did not reach significance. Age, ethnicity (Dravidian versus Aryan), smoking, alcohol consumption, and the interval between drawing the blood sample and its analysis were factors that did not produce statistically significant differences in the T-cell subsets studied. When compared with other published series, the CD4 and CD8 values in healthy Indians were no different from those reported in the West. These observations have important clinical implications for the use of T-lymphocyte subset measurements in India, especially in the management of HIV infection. The normal ranges established by this study can be used as a reference for decisions made in clinical practice.","internal_url":"https://www.academia.edu/104431497/Normal_values_of_CD4_and_CD8_lymphocyte_subsets_in_healthy_indian_adults_and_the_effects_of_sex_age_ethnicity_and_smoking","translated_internal_url":"","created_at":"2023-07-10T08:05:26.735-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":172202773,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Normal_values_of_CD4_and_CD8_lymphocyte_subsets_in_healthy_indian_adults_and_the_effects_of_sex_age_ethnicity_and_smoking","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":172202773,"first_name":"Paramjit","middle_initials":null,"last_name":"Dhot","page_name":"PDhot","domain_name":"independent","created_at":"2020-09-28T17:10:23.981-07:00","display_name":"Paramjit 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/></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/104431504/Futuristic_Scope_of_Stem_Cells_in_Medicine">Futuristic Scope of Stem Cells in Medicine</a></div><div class="wp-workCard_item"><span>Asian Journal of Pharmaceutical and Clinical Research</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The most potential application of the stem cells (SCs) in human beings lies in their ability to r...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The most potential application of the stem cells (SCs) in human beings lies in their ability to regenerate cells and tissues. They differentiate themselves into specific cell type, thereby availing remarkable source of replacement cells and tissues. They differentiate themselves into specific cell types, thereby availing renewable source of replacement cells and tissues. Their potential of regeneration has now opened many avenues in the field of medical science and research. As a therapeutic adjuvant in near future, the SCs will emerge as an efficient technique to completely heal a number of diseases including diabetes, heart diseases and strokes, osteoarthritis, rheumatoid arthritis, and macular degeneration. The researches, which are underway, some of them will surely be proved as safe and effective SC treatment in the market in due course of time. 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Keywords: Stem cells, Medicine, Embryonic cells, Heart disease.","publication_date":{"day":null,"month":null,"year":2016,"errors":{}},"publication_name":"Asian Journal of Pharmaceutical and Clinical Research"},"translated_abstract":"The most potential application of the stem cells (SCs) in human beings lies in their ability to regenerate cells and tissues. They differentiate themselves into specific cell type, thereby availing remarkable source of replacement cells and tissues. They differentiate themselves into specific cell types, thereby availing renewable source of replacement cells and tissues. Their potential of regeneration has now opened many avenues in the field of medical science and research. As a therapeutic adjuvant in near future, the SCs will emerge as an efficient technique to completely heal a number of diseases including diabetes, heart diseases and strokes, osteoarthritis, rheumatoid arthritis, and macular degeneration. The researches, which are underway, some of them will surely be proved as safe and effective SC treatment in the market in due course of time. Keywords: Stem cells, Medicine, Embryonic cells, Heart disease.","internal_url":"https://www.academia.edu/104431504/Futuristic_Scope_of_Stem_Cells_in_Medicine","translated_internal_url":"","created_at":"2023-07-10T08:05:28.110-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":172202773,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Futuristic_Scope_of_Stem_Cells_in_Medicine","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":172202773,"first_name":"Paramjit","middle_initials":null,"last_name":"Dhot","page_name":"PDhot","domain_name":"independent","created_at":"2020-09-28T17:10:23.981-07:00","display_name":"Paramjit Dhot","url":"https://independent.academia.edu/PDhot"},"attachments":[],"research_interests":[{"id":12733,"name":"Rheumatoid Arthritis","url":"https://www.academia.edu/Documents/in/Rheumatoid_Arthritis"},{"id":23163,"name":"Stem Cell","url":"https://www.academia.edu/Documents/in/Stem_Cell"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":106582,"name":"Embryonic Stem Cell","url":"https://www.academia.edu/Documents/in/Embryonic_Stem_Cell"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="104431503"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/104431503/Scope_of_Gas_Chromatography_Mass_Spectrometry_in_Inborn_Errors_of_Metabolism_Screening_A_Review"><img alt="Research paper thumbnail of Scope of Gas Chromatography-Mass Spectrometry in Inborn Errors of Metabolism Screening: A Review" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/104431503/Scope_of_Gas_Chromatography_Mass_Spectrometry_in_Inborn_Errors_of_Metabolism_Screening_A_Review">Scope of Gas Chromatography-Mass Spectrometry in Inborn Errors of Metabolism Screening: A Review</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Inborn errors of metabolism (IEM) arise from inherited errors in enzyme in any of the metabolic p...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Inborn errors of metabolism (IEM) arise from inherited errors in enzyme in any of the metabolic pathways. Symptoms are developed due to the accumulation of biosynthetic precursors or product that baby cannot excrete. IEM screening is a field that is undergoing a revolutionary change in its all aspects. Technological advances are transforming the way in which we can diagnose the whole population of IEM. In last few decades, evolution of gas chromatography-mass spectrometry (GC-MS) has improved our diagnostic capabilities in many fields. It is now possible to screen rapidly, simultaneously and inexpensively for a number of very rare disorders using GC-MS. Recent developments in the field of analytical and separation science and MS has brought about great improvement in GC-MS efficiency and sensitivity. The use of this technique in newborn screening made it possible in the present scenario, to screen for a wide range of previously unscreened IEM, including aminoacidemias, fatty acid ox...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104431503"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104431503"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104431503; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104431503]").text(description); $(".js-view-count[data-work-id=104431503]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104431503; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104431503']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104431503, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=104431503]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104431503,"title":"Scope of Gas Chromatography-Mass Spectrometry in Inborn Errors of Metabolism Screening: A Review","translated_title":"","metadata":{"abstract":"Inborn errors of metabolism (IEM) arise from inherited errors in enzyme in any of the metabolic pathways. Symptoms are developed due to the accumulation of biosynthetic precursors or product that baby cannot excrete. IEM screening is a field that is undergoing a revolutionary change in its all aspects. Technological advances are transforming the way in which we can diagnose the whole population of IEM. In last few decades, evolution of gas chromatography-mass spectrometry (GC-MS) has improved our diagnostic capabilities in many fields. It is now possible to screen rapidly, simultaneously and inexpensively for a number of very rare disorders using GC-MS. Recent developments in the field of analytical and separation science and MS has brought about great improvement in GC-MS efficiency and sensitivity. The use of this technique in newborn screening made it possible in the present scenario, to screen for a wide range of previously unscreened IEM, including aminoacidemias, fatty acid ox...","publication_date":{"day":null,"month":null,"year":2015,"errors":{}}},"translated_abstract":"Inborn errors of metabolism (IEM) arise from inherited errors in enzyme in any of the metabolic pathways. Symptoms are developed due to the accumulation of biosynthetic precursors or product that baby cannot excrete. IEM screening is a field that is undergoing a revolutionary change in its all aspects. Technological advances are transforming the way in which we can diagnose the whole population of IEM. In last few decades, evolution of gas chromatography-mass spectrometry (GC-MS) has improved our diagnostic capabilities in many fields. It is now possible to screen rapidly, simultaneously and inexpensively for a number of very rare disorders using GC-MS. Recent developments in the field of analytical and separation science and MS has brought about great improvement in GC-MS efficiency and sensitivity. The use of this technique in newborn screening made it possible in the present scenario, to screen for a wide range of previously unscreened IEM, including aminoacidemias, fatty acid ox...","internal_url":"https://www.academia.edu/104431503/Scope_of_Gas_Chromatography_Mass_Spectrometry_in_Inborn_Errors_of_Metabolism_Screening_A_Review","translated_internal_url":"","created_at":"2023-07-10T08:05:27.976-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":172202773,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Scope_of_Gas_Chromatography_Mass_Spectrometry_in_Inborn_Errors_of_Metabolism_Screening_A_Review","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":172202773,"first_name":"Paramjit","middle_initials":null,"last_name":"Dhot","page_name":"PDhot","domain_name":"independent","created_at":"2020-09-28T17:10:23.981-07:00","display_name":"Paramjit Dhot","url":"https://independent.academia.edu/PDhot"},"attachments":[],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64336,"name":"Population","url":"https://www.academia.edu/Documents/in/Population"},{"id":197938,"name":"Newborn Screening","url":"https://www.academia.edu/Documents/in/Newborn_Screening"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="104431502"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/104431502/Yoga_Practice_and_Biochemical_and_Physiological_Alterations_in_Normal_Subjects"><img alt="Research paper thumbnail of Yoga Practice and Biochemical and Physiological Alterations in Normal Subjects" class="work-thumbnail" src="https://attachments.academia-assets.com/104163539/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/104431502/Yoga_Practice_and_Biochemical_and_Physiological_Alterations_in_Normal_Subjects">Yoga Practice and Biochemical and Physiological Alterations in Normal Subjects</a></div><div class="wp-workCard_item"><span>Asian Journal of Pharmaceutical and Clinical Research</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Objective: To assess the effect of 45 minute yogic kriya (Surya Namaskar and Kapalbhati) for 30 d...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Objective: To assess the effect of 45 minute yogic kriya (Surya Namaskar and Kapalbhati) for 30 days on various physiological and biochemical parameters. Methods: About 20 Nursing College students of the Santosh Medical University, Ghaziabad, between the age group 17 and 21 years volunteered to participate in the study. They were divided into two Groups A and B. Group A students including 10 students in each group were subjected to 30 days yoge kriya for 45 minutes for 6 days in a week. Statistical analysis: A student’s t-test was used for comparing the means of pre- and post-yoga results of various parameters. Results: No significant difference was found in systolic blood pressure, pulse, body mass index, hemoglobin except for fasting blood sugar and diastolic blood pressure (p&lt;0.001) among the yoga subject while comparing with baseline values and control. Keywords: Yoga, Biochemical alterations, Physiological alterations, Surya Namaskar and Kapal Bhati.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="5931cd286242ddf7d2e73a3363d9ac80" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":104163539,"asset_id":104431502,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/104163539/download_file?st=MTczMjQ2NzMyMyw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104431502"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104431502"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104431502; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104431502]").text(description); $(".js-view-count[data-work-id=104431502]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104431502; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104431502']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104431502, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "5931cd286242ddf7d2e73a3363d9ac80" } } $('.js-work-strip[data-work-id=104431502]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104431502,"title":"Yoga Practice and Biochemical and Physiological Alterations in Normal Subjects","translated_title":"","metadata":{"abstract":"Objective: To assess the effect of 45 minute yogic kriya (Surya Namaskar and Kapalbhati) for 30 days on various physiological and biochemical parameters. Methods: About 20 Nursing College students of the Santosh Medical University, Ghaziabad, between the age group 17 and 21 years volunteered to participate in the study. They were divided into two Groups A and B. Group A students including 10 students in each group were subjected to 30 days yoge kriya for 45 minutes for 6 days in a week. Statistical analysis: A student’s t-test was used for comparing the means of pre- and post-yoga results of various parameters. Results: No significant difference was found in systolic blood pressure, pulse, body mass index, hemoglobin except for fasting blood sugar and diastolic blood pressure (p\u0026lt;0.001) among the yoga subject while comparing with baseline values and control. Keywords: Yoga, Biochemical alterations, Physiological alterations, Surya Namaskar and Kapal Bhati.","publication_date":{"day":null,"month":null,"year":2016,"errors":{}},"publication_name":"Asian Journal of Pharmaceutical and Clinical Research"},"translated_abstract":"Objective: To assess the effect of 45 minute yogic kriya (Surya Namaskar and Kapalbhati) for 30 days on various physiological and biochemical parameters. Methods: About 20 Nursing College students of the Santosh Medical University, Ghaziabad, between the age group 17 and 21 years volunteered to participate in the study. They were divided into two Groups A and B. Group A students including 10 students in each group were subjected to 30 days yoge kriya for 45 minutes for 6 days in a week. Statistical analysis: A student’s t-test was used for comparing the means of pre- and post-yoga results of various parameters. Results: No significant difference was found in systolic blood pressure, pulse, body mass index, hemoglobin except for fasting blood sugar and diastolic blood pressure (p\u0026lt;0.001) among the yoga subject while comparing with baseline values and control. Keywords: Yoga, Biochemical alterations, Physiological alterations, Surya Namaskar and Kapal Bhati.","internal_url":"https://www.academia.edu/104431502/Yoga_Practice_and_Biochemical_and_Physiological_Alterations_in_Normal_Subjects","translated_internal_url":"","created_at":"2023-07-10T08:05:27.818-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":172202773,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":104163539,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/104163539/thumbnails/1.jpg","file_name":"admin_2C_Journal_manager_2C_47_AJPCR_10342_RA.pdf_filename_UTF-8admin_2C_Journal_manager_2C_47_AJPCR_10342_RA.pdf","download_url":"https://www.academia.edu/attachments/104163539/download_file?st=MTczMjQ2NzMyMyw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Yoga_Practice_and_Biochemical_and_Physio.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/104163539/admin_2C_Journal_manager_2C_47_AJPCR_10342_RA.pdf_filename_UTF-8admin_2C_Journal_manager_2C_47_AJPCR_10342_RA-libre.pdf?1689004137=\u0026response-content-disposition=attachment%3B+filename%3DYoga_Practice_and_Biochemical_and_Physio.pdf\u0026Expires=1732442518\u0026Signature=FwmXfMWWPRNLeOb0MHT4okz79sub~oqy63VsgSl4eq-49q-uzDMoPVRqZ8ebMMWYtHjRpj2BLsiVqapwu1~YzVw88knk0RLxkrfs01IEP4ZHLllFUyB-4pr5qpkc1bUcu5CkAZZb-rS7KLs9bn6b4Qnc7qx64z12YOTW4bOk31urO5Ydmbsy89ZIgzPP5eOQGVsIf7btyacMIOCsVHW-aHoGb7U0~H4TLYO1ZlGsIpAlozY8IaEqPGsdEtxDz7nM5BB-FgG~fOJUuU-YOOOam3dbHlzs538Zo-HmdlwYg~Gm4N-~KrkPJtdAb~XMSIB0bGtT12z47GvyUeWzBSj1rA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Yoga_Practice_and_Biochemical_and_Physiological_Alterations_in_Normal_Subjects","translated_slug":"","page_count":3,"language":"en","content_type":"Work","owner":{"id":172202773,"first_name":"Paramjit","middle_initials":null,"last_name":"Dhot","page_name":"PDhot","domain_name":"independent","created_at":"2020-09-28T17:10:23.981-07:00","display_name":"Paramjit 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data-click-track="profile-work-strip-title" href="https://www.academia.edu/104431499/Platelet_function_disorders_in_north_India">Platelet function disorders in north India</a></div><div class="wp-workCard_item"><span>The National medical journal of India</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Platelet function disorders are a fairly common cause of bleeding manifestations. Although their ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Platelet function disorders are a fairly common cause of bleeding manifestations. Although their relative types and incidence are well documented, data from India are lacking. Between 1970 and 1991, we studied the clinical and laboratory features of 144 north Indian patients who presented to our hospital with a bleeding diathesis in whom coagulation disorders, von Willebrand&#39;s disease and a history of drug ingestion were absent. Isolated platelet factor 3 availability defect was the commonest (56 cases) followed by the thrombasthenias (49 cases), arachidonic acid pathway defect (26 cases), storage pool disease (8 cases) and the Bernard-Soulier syndrome (3 cases). Isolated platelet factor 3 deficiency was rare (2 cases). Two varieties of thrombasthenia were seen--the classical Glanzmann&#39;s (13 cases) and thrombopathic (36 cases). The latter was characterized by absent or sub-normal platelet aggregation with agonists along with a reduced (to less than 50% of normal) total plate...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104431499"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104431499"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104431499; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104431499]").text(description); $(".js-view-count[data-work-id=104431499]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104431499; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104431499']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104431499, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=104431499]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104431499,"title":"Platelet function disorders in north India","translated_title":"","metadata":{"abstract":"Platelet function disorders are a fairly common cause of bleeding manifestations. Although their relative types and incidence are well documented, data from India are lacking. Between 1970 and 1991, we studied the clinical and laboratory features of 144 north Indian patients who presented to our hospital with a bleeding diathesis in whom coagulation disorders, von Willebrand\u0026#39;s disease and a history of drug ingestion were absent. Isolated platelet factor 3 availability defect was the commonest (56 cases) followed by the thrombasthenias (49 cases), arachidonic acid pathway defect (26 cases), storage pool disease (8 cases) and the Bernard-Soulier syndrome (3 cases). Isolated platelet factor 3 deficiency was rare (2 cases). Two varieties of thrombasthenia were seen--the classical Glanzmann\u0026#39;s (13 cases) and thrombopathic (36 cases). The latter was characterized by absent or sub-normal platelet aggregation with agonists along with a reduced (to less than 50% of normal) total plate...","publication_name":"The National medical journal of India"},"translated_abstract":"Platelet function disorders are a fairly common cause of bleeding manifestations. Although their relative types and incidence are well documented, data from India are lacking. Between 1970 and 1991, we studied the clinical and laboratory features of 144 north Indian patients who presented to our hospital with a bleeding diathesis in whom coagulation disorders, von Willebrand\u0026#39;s disease and a history of drug ingestion were absent. Isolated platelet factor 3 availability defect was the commonest (56 cases) followed by the thrombasthenias (49 cases), arachidonic acid pathway defect (26 cases), storage pool disease (8 cases) and the Bernard-Soulier syndrome (3 cases). Isolated platelet factor 3 deficiency was rare (2 cases). Two varieties of thrombasthenia were seen--the classical Glanzmann\u0026#39;s (13 cases) and thrombopathic (36 cases). The latter was characterized by absent or sub-normal platelet aggregation with agonists along with a reduced (to less than 50% of normal) total plate...","internal_url":"https://www.academia.edu/104431499/Platelet_function_disorders_in_north_India","translated_internal_url":"","created_at":"2023-07-10T08:05:27.118-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":172202773,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Platelet_function_disorders_in_north_India","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":172202773,"first_name":"Paramjit","middle_initials":null,"last_name":"Dhot","page_name":"PDhot","domain_name":"independent","created_at":"2020-09-28T17:10:23.981-07:00","display_name":"Paramjit Dhot","url":"https://independent.academia.edu/PDhot"},"attachments":[],"research_interests":[{"id":5500,"name":"Incidence Geometry","url":"https://www.academia.edu/Documents/in/Incidence_Geometry"},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":43838,"name":"India","url":"https://www.academia.edu/Documents/in/India"},{"id":52136,"name":"Platelet","url":"https://www.academia.edu/Documents/in/Platelet"},{"id":58185,"name":"Medical tourism india","url":"https://www.academia.edu/Documents/in/Medical_tourism_india"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":111545,"name":"Male","url":"https://www.academia.edu/Documents/in/Male"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":382075,"name":"Adult","url":"https://www.academia.edu/Documents/in/Adult"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="104431498"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/104431498/Acquired_deficiency_of_factor_XIII"><img alt="Research paper thumbnail of Acquired deficiency of factor XIII" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/104431498/Acquired_deficiency_of_factor_XIII">Acquired deficiency of factor XIII</a></div><div class="wp-workCard_item"><span>The Journal of the Association of Physicians of India</span><span>, 1994</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104431498"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104431498"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104431498; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104431498]").text(description); $(".js-view-count[data-work-id=104431498]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104431498; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104431498']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104431498, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=104431498]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104431498,"title":"Acquired deficiency of factor XIII","translated_title":"","metadata":{"publication_date":{"day":null,"month":null,"year":1994,"errors":{}},"publication_name":"The Journal of the Association of Physicians of India"},"translated_abstract":null,"internal_url":"https://www.academia.edu/104431498/Acquired_deficiency_of_factor_XIII","translated_internal_url":"","created_at":"2023-07-10T08:05:26.966-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":172202773,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Acquired_deficiency_of_factor_XIII","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":172202773,"first_name":"Paramjit","middle_initials":null,"last_name":"Dhot","page_name":"PDhot","domain_name":"independent","created_at":"2020-09-28T17:10:23.981-07:00","display_name":"Paramjit Dhot","url":"https://independent.academia.edu/PDhot"},"attachments":[],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":64568,"name":"Humans","url":"https://www.academia.edu/Documents/in/Humans"},{"id":98925,"name":"Female","url":"https://www.academia.edu/Documents/in/Female"},{"id":295155,"name":"Middle Aged","url":"https://www.academia.edu/Documents/in/Middle_Aged"},{"id":1518796,"name":"Leiomyoma","url":"https://www.academia.edu/Documents/in/Leiomyoma"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="104431497"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/104431497/Normal_values_of_CD4_and_CD8_lymphocyte_subsets_in_healthy_indian_adults_and_the_effects_of_sex_age_ethnicity_and_smoking"><img alt="Research paper thumbnail of Normal values of CD4 and CD8 lymphocyte subsets in healthy indian adults and the effects of sex, age, ethnicity, and smoking" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/104431497/Normal_values_of_CD4_and_CD8_lymphocyte_subsets_in_healthy_indian_adults_and_the_effects_of_sex_age_ethnicity_and_smoking">Normal values of CD4 and CD8 lymphocyte subsets in healthy indian adults and the effects of sex, age, ethnicity, and smoking</a></div><div class="wp-workCard_item"><span>Cytometry</span><span>, 2003</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Information on lymphocyte populations (T, B, and natural killer cells) and subpopulations (CD4 an...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Information on lymphocyte populations (T, B, and natural killer cells) and subpopulations (CD4 and CD8) in India is generally lacking. Measurement of T-cell subsets is important in India for evaluating disease stage and progression in individuals with the human immunodeficiency virus (HIV). Hence, this study was conducted to provide normal ranges of absolute and percentage values of CD4 and CD8 T-lymphocyte subsets and the ratio of CD4 to CD8 in normal Indian adults. Flow cytometric analysis (EPICS-XL) was used to determine the range of T-lymphocyte subpopulations in normal Indian blood donors at Command Hospital and the Armed Forces Medical College, Pune, India. The reference population consisted of 94 healthy HIV-seronegative blood donors. T-lymphocyte subsets were analyzed with two-color immunophenotyping of peripheral blood lymphocytes with the use of a lysed whole-blood technique and enumerated. For normal values of various blood components, we found mean values of 2114 cells/microl for total lymphocytes, 865 cells/microl (40.2%) for CD4(+) lymphocytes, 552 cells/microl (31.3%) for CD8(+) lymphocytes, and 1.7 for the CD4:CD8 ratio. The 95% confidence intervals for the same parameters were 1115-4009 cells/microl, 430-1740 cells/microl (30.75-49.60%), 218-1396 cells/microl (20.06-42.52%), and 0.39-3.02 respectively. Females had significantly higher CD4 counts (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05), percentage of CD4 lymphocytes (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01), and CD4:CD8 ratio (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Males had a significantly higher percentage of CD8 lymphocytes (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). They also had higher CD8 counts that did not reach significance. Age, ethnicity (Dravidian versus Aryan), smoking, alcohol consumption, and the interval between drawing the blood sample and its analysis were factors that did not produce statistically significant differences in the T-cell subsets studied. When compared with other published series, the CD4 and CD8 values in healthy Indians were no different from those reported in the West. These observations have important clinical implications for the use of T-lymphocyte subset measurements in India, especially in the management of HIV infection. The normal ranges established by this study can be used as a reference for decisions made in clinical practice.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="104431497"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="104431497"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 104431497; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=104431497]").text(description); $(".js-view-count[data-work-id=104431497]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 104431497; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='104431497']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 104431497, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=104431497]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":104431497,"title":"Normal values of CD4 and CD8 lymphocyte subsets in healthy indian adults and the effects of sex, age, ethnicity, and smoking","translated_title":"","metadata":{"abstract":"Information on lymphocyte populations (T, B, and natural killer cells) and subpopulations (CD4 and CD8) in India is generally lacking. Measurement of T-cell subsets is important in India for evaluating disease stage and progression in individuals with the human immunodeficiency virus (HIV). Hence, this study was conducted to provide normal ranges of absolute and percentage values of CD4 and CD8 T-lymphocyte subsets and the ratio of CD4 to CD8 in normal Indian adults. Flow cytometric analysis (EPICS-XL) was used to determine the range of T-lymphocyte subpopulations in normal Indian blood donors at Command Hospital and the Armed Forces Medical College, Pune, India. The reference population consisted of 94 healthy HIV-seronegative blood donors. T-lymphocyte subsets were analyzed with two-color immunophenotyping of peripheral blood lymphocytes with the use of a lysed whole-blood technique and enumerated. For normal values of various blood components, we found mean values of 2114 cells/microl for total lymphocytes, 865 cells/microl (40.2%) for CD4(+) lymphocytes, 552 cells/microl (31.3%) for CD8(+) lymphocytes, and 1.7 for the CD4:CD8 ratio. The 95% confidence intervals for the same parameters were 1115-4009 cells/microl, 430-1740 cells/microl (30.75-49.60%), 218-1396 cells/microl (20.06-42.52%), and 0.39-3.02 respectively. Females had significantly higher CD4 counts (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05), percentage of CD4 lymphocytes (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01), and CD4:CD8 ratio (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Males had a significantly higher percentage of CD8 lymphocytes (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). They also had higher CD8 counts that did not reach significance. Age, ethnicity (Dravidian versus Aryan), smoking, alcohol consumption, and the interval between drawing the blood sample and its analysis were factors that did not produce statistically significant differences in the T-cell subsets studied. When compared with other published series, the CD4 and CD8 values in healthy Indians were no different from those reported in the West. These observations have important clinical implications for the use of T-lymphocyte subset measurements in India, especially in the management of HIV infection. The normal ranges established by this study can be used as a reference for decisions made in clinical practice.","publisher":"Wiley","publication_date":{"day":null,"month":null,"year":2003,"errors":{}},"publication_name":"Cytometry"},"translated_abstract":"Information on lymphocyte populations (T, B, and natural killer cells) and subpopulations (CD4 and CD8) in India is generally lacking. Measurement of T-cell subsets is important in India for evaluating disease stage and progression in individuals with the human immunodeficiency virus (HIV). Hence, this study was conducted to provide normal ranges of absolute and percentage values of CD4 and CD8 T-lymphocyte subsets and the ratio of CD4 to CD8 in normal Indian adults. Flow cytometric analysis (EPICS-XL) was used to determine the range of T-lymphocyte subpopulations in normal Indian blood donors at Command Hospital and the Armed Forces Medical College, Pune, India. The reference population consisted of 94 healthy HIV-seronegative blood donors. T-lymphocyte subsets were analyzed with two-color immunophenotyping of peripheral blood lymphocytes with the use of a lysed whole-blood technique and enumerated. For normal values of various blood components, we found mean values of 2114 cells/microl for total lymphocytes, 865 cells/microl (40.2%) for CD4(+) lymphocytes, 552 cells/microl (31.3%) for CD8(+) lymphocytes, and 1.7 for the CD4:CD8 ratio. The 95% confidence intervals for the same parameters were 1115-4009 cells/microl, 430-1740 cells/microl (30.75-49.60%), 218-1396 cells/microl (20.06-42.52%), and 0.39-3.02 respectively. Females had significantly higher CD4 counts (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05), percentage of CD4 lymphocytes (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01), and CD4:CD8 ratio (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Males had a significantly higher percentage of CD8 lymphocytes (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). They also had higher CD8 counts that did not reach significance. Age, ethnicity (Dravidian versus Aryan), smoking, alcohol consumption, and the interval between drawing the blood sample and its analysis were factors that did not produce statistically significant differences in the T-cell subsets studied. When compared with other published series, the CD4 and CD8 values in healthy Indians were no different from those reported in the West. These observations have important clinical implications for the use of T-lymphocyte subset measurements in India, especially in the management of HIV infection. 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