George R. Minot

<html> <head> <title>George R. Minot</title> <meta name="googlebot" content="noodp"> <meta name="robots" content="noodp"> <link rel="apple-touch-icon-precomposed" href="/silly-nndb-icon.png" /><style type="text/css">  </style></head> <body bgcolor=#ffffff> <center> <table cellpadding=0 cellspacing=0 border=0><tr><td valign=top><table width=550 cellpadding=0 cellspacing=0><tr><td bgcolor=white><table width="100%" cellpadding="4" cellspacing="0" background="/nndb.gif"> <tr> <td rowspan="2" align="left" valign="top"><a href="http://www.nndb.com/"><img src="/title.gif" width="260" height="50" border=0 alt="NNDB"></a></td> <td><table width="100%" cellspacing="0" cellpadding="6"> <tr align="center"> <td width="25%" nowrap>This is a beta version of NNDB</td> </tr> </table></td> </tr> <tr> <td align="right" valign="middle"> <form action="http://search.nndb.com/search/nndb.cgi" method="get"> <input type="hidden" name="nndb" value="1"></input> Search: <select name="omenu"> <option value="unspecified" selected>All Names</option> <option value="living">Living people</option> <option value="dead">Dead people</option> <option value="bands">Band Names</option> <option value="books">Book Titles</option> <option value="movies">Movie Titles</option> <option value="fulltext">Full Text</option> </select> for <input name="query" value="" size=24 maxlength=96> <input type=submit value="Search"> </form></td> </tr> </table>        </td></tr><tr><td bgcolor=red height=2></td></tr><map name=fool><area coords="102,0,240,14" href="/people/228/000127844/bibliography/" alt="bibliography"></map><tr bgcolor=F0F0F0><td bgcolor=F0F0F0 style="padding: 0px 15px 15px 15px;"><img src="/red-profile-2.gif" align="right" height=15 width=240 border=0 usemap=#fool> <table cellpadding=0 cellspacing=0 width=100%><tr><td bgcolor=F0F0F0>George R. Minot<img src="george-r-minot.jpg" height=330 width=220 align=right hspace=10 vspace=10 alt="George R. Minot">AKA George Richards MinotBorn: <a href="/lists/854/000106536/" class=proflink>2-Dec</a>-<a href="/lists/884/000105569/" class=proflink>1885</a> Birthplace: <a href="/geo/430/000069223/" class=proflink>Boston, MA</a> Died: <a href="/lists/939/000106621/" class=proflink>25-Feb</a>-<a href="/lists/460/000106142/" class=proflink>1950</a> Location of death: <a href="/geo/435/000069228/" class=proflink>Brookline, MA</a> Cause of death: unspecified Gender: Male Religion: <a href="/lists/279/000069072/" class=proflink>Unitarian</a> Race or Ethnicity: White Sexual orientation: Straight Occupation: <a href="/lists/632/000096344/" class=proflink>Doctor</a>Nationality: United States Executive summary: Liver therapy for pernicious anemiaGeorge Minot researched numerous blood disorders, including leukemia, and made his most famous discovery by isolating a treatment for pernicious anemia. Though we now think of this as a relatively minor ailment, in the early 20th century it was a deadly disease. Minot meticulously recorded the diets of patients with anemia, seeking a unifying factor that might lead to a cause and a cure. Following up on the research of <a href="/people/092/000127708/">George H. Whipple</a>, Minot and his colleague <a href="/people/287/000127903/">William P. Murphy</a> fed liver to patients suffering from pernicious anemia -- basically, feeding them liver until they could stand to eat no more. Their findings showed that the ingestion of one half-pound of liver daily effectively reversed the course of the disease. In collaboration with chemist Edwin Cohn, Minot and Murphy then formulated an effective liver extract, and showed that a very small quantity of this extract, administered intravenously, had the same effect as eating huge quantities of liver. This became the standard treatment for pernicious anemia until Vitamin B-12 was isolated, two decades later. For their life-saving work, Minot, Murphy, and Whipple shared the 1934 Nobel Prize in Physiology or Medicine. He married Marian Linzee Weld, who had been his next-door neighbor in childhood. A member of the Boston blueblood Minot family, he was distantly related to 1890s Secretary of State <a href="/people/070/000102761/">Richard Olney</a> and 1990s Massachusetts Governor <a href="/people/491/000063302/">Bill Weld</a>.Father: James Jackson Minot (physician, b. 1853, d. 1938) Mother: Elizabeth Whitney Minot (b. 1860, d. 1903) Brother: James Jackson Minot Jr (stockbroker, b. 17-Nov-1891, d. 5-Sep-1985) Brother: Henry Whitney Minot (b. 6-Feb-1896, 15-Apr-1971) Wife: Marian Linzee Weld (b. 17-May-1890, m. 29-Jun-1915, d. 1979) Daughter: Marian Linzee Minot (b. 6-Oct-1918) Daughter: Elizabeth Whitney Minot (b. 4-Dec-1920) Son: Charles Sedgwick Minot (physician, b. 18-Mar-1930)     University: <a href="/edu/473/000068269/">BA, Harvard University (1908)</a>     Medical School: <a href="/edu/403/000127022/">MD, Harvard Medical School (1912)</a>     Teacher: <a href="/edu/633/000068429/">Medicine, Johns Hopkins University (1913-15)</a>     Teacher: <a href="/edu/403/000127022/">Medicine, Harvard Medical School (1915-28)</a>     Professor: <a href="/edu/403/000127022/">Medicine, Harvard Medical School (1928-47)</a>     <a href="/honors/214/000068010/">Nobel Prize for Medicine</a> 1934 (with <a href="/people/092/000127708/">George H. Whipple</a> and <a href="/people/287/000127903/">William P. Murphy</a>)     Risk Factors: <a href="/lists/783/000064591/">Diabetes</a> Do you know something we don't? <a href="http://commentary.nndb.com/submit/feedback/?id=127844" rel="nofollow">Submit a correction or make a comment about this profile</a> Copyright ©2019 Soylent Communications </td></tr></table> </td></tr> </table> </td> <td width=180 align="center" valign="top" style="padding: 0px 0px 8px 25px;"></td></tr> </table> </center> </body> </html>

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George R. Minot