Innovation in Pediatric Healthcare | Children's Hospital of Philadelphia

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</span> </a> </li> <li class="tertiary-nav__menu-item tertiary-nav__menu-item--link tertiary-nav__menu-item--level-1"> <a href="/caring-for-your-child" class="tertiary-nav__menu-link tertiary-nav__menu-link--link tertiary-nav__menu-link--level-1" data-drupal-link-system-path="caring-for-your-child"> <span class="tertiary-nav__menu-link-inner tertiary-nav__menu-link-inner--level-2"> Caring for your child </span> </a> </li> <li class="tertiary-nav__menu-item tertiary-nav__menu-item--link tertiary-nav__menu-item--level-1"> <a href="/patients-and-visitors/obtaining-medical-records" class="tertiary-nav__menu-link tertiary-nav__menu-link--link tertiary-nav__menu-link--level-1" data-drupal-link-system-path="node/115284"> <span class="tertiary-nav__menu-link-inner tertiary-nav__menu-link-inner--level-2"> Request medical records </span> </a> </li> <li class="tertiary-nav__menu-item tertiary-nav__menu-item--link tertiary-nav__menu-item--level-1"> <a href="/research-studies" 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gap-size="small" y-padding="small"> <chop-column class="layout__region layout__region--main gap-y-4 md:gap-y-16" col-span-default="12" row-span="1" vertical-align="top"> <chop-breadcrumb> <nav slot="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 data="data-jump-nav-exclude" id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ul> <li> <a href="/">Home</a> </li> <li> Innovation In Pediatric Healthcare </li> </ul> </nav> </chop-breadcrumb> </chop-column> </chop-grid> </div> <div class="hidden block block-chop-alert block-chop-alert-content" id="block-outline-frontend-displaychopalertsincontentcontext"> </div> <div id="block-outline-frontend-mainpagecontent" class="block block-system block-system-main-block"> <article> <chop-container container-width="full"> <div class="node--content-wrapper"> <chop-grid class="layout one-col one-col--dynamic relative" background-color="transparent" background-svg="none" content-max-width="medium" gap-size="small" vertical-align="top" x-padding="true" > <chop-column class="layout__region layout__region--main gap-4 md:gap-y-16" vertical-align="top" horizontal-align="left" col-span-default="12" col-span-md="12" > <div class="block block-layout_builder block-icon_heading block-layout-builder block-inline-blockicon-heading"> <chop-icon-heading variant="default" background-color="transparent" icon-name="logomark" accent-color="dark_pink" > <chop-heading slot="heading" level-size="lg"> <h2>Solving the Unsolvable: Innovation at CHOP</h2> </chop-heading> <div slot="description"> <div><chop-styled-text><p>At Children’s Hospital of Philadelphia (CHOP), we lead the world in our relentless pursuit of solutions for the biggest pediatric challenges. Our hospital has become a haven for hope and a place where the unbelievable can happen – where innovation meets compassion and hope can turn into healing. </p><p> </p></chop-styled-text></div> </div> </chop-icon-heading> </div> </chop-column> </chop-grid> <chop-grid class="layout full-width full-width--dynamic relative" background-color="transparent" background-svg="none" content-max-width="full_width" gap-size="" vertical-align="" > <chop-column class="layout__region layout__region--main gap-4 md:gap-y-16" vertical-align="" horizontal-align="" col-span-default="12" col-span-md="12" > <div class="block block-layout_builder block-video_hero block-layout-builder block-inline-blockvideo-hero"> <chop-attribute-cascade data-string="chop-video-player,variation,hero;chop-video-player,overlay,,"> <chop-video-hero accent-color="green" background-color="dark_blue" > <div slot="video"> <div><chop-video-player video-url="https://www.chop.edu/sites/default/files/2024-06/innovation-b-roll-1.mp4" variation="location-hero" > </chop-video-player> </div> </div> </chop-video-hero> </chop-attribute-cascade> </div> </chop-column> </chop-grid> <chop-grid class="layout one-col one-col--dynamic relative" background-color="light_beige" background-svg="none" content-max-width="small" gap-size="small" vertical-align="top" y-padding="large" x-padding="true" > <chop-column class="layout__region layout__region--main gap-4 md:gap-y-16" vertical-align="top" horizontal-align="left" col-span-default="12" col-span-md="12" > <div class="block block-layout_builder block-horizontal_wysiwyg_cards block-layout-builder block-inline-blockhorizontal-wysiwyg-cards"> <div> <chop-column class="gap-y-4 md:gap-y-12" vertical-align="top" horizontal-align="left" col-span-default="12" col-span-md="9" hide-first-jumpnav-jump > <chop-wysiwyg-card variation="stacked-circle" accent-color="light_blue" icon-name=""> <chop-styled-text slot="description"> <p>CHOP has consistently been at the forefront of clinical care and scientific discovery, with a focus on delivering better outcomes. Our physicians are pioneers and trailblazers with deep multidisciplinary expertise, and our 45 pediatric subspecialties are nationally and internationally recognized, with all our programs ranked, year after year. From precision diagnostics to novel therapeutics to world-class care that places families at the center, our uniquely comprehensive bench-to-bedside approach has led to countless breakthroughs and saved countless children’s lives.</p> </chop-styled-text> </chop-wysiwyg-card> </chop-column> </div> </div> </chop-column> </chop-grid> <chop-grid class="layout one-col one-col--dynamic relative" background-color="transparent" background-svg="none" content-max-width="medium" gap-size="small" vertical-align="top" y-padding="small" x-padding="true" > <chop-column class="layout__region layout__region--main gap-4 md:gap-y-16" vertical-align="top" horizontal-align="left" col-span-default="12" col-span-md="12" > <div class="block block-layout_builder block-card_image block-layout-builder block-inline-blockcard-image"> <chop-feature-card image-position="left" rectangle-color="blue" background-color="dark_pink" > <div slot="image"> <div class="media media--type-image media--view-mode-feature-card"> 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/sites/default/files/styles/landscape_150_3x2_4000x2667_2x/public/2024-10/Photo-arleys-story-2624x1720-v01.jpg?itok=y55VMz1f 4000w" type="image/jpeg" sizes="100vw" width="960" height="640"/> <img width="160" height="107" src="/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-10/Photo-arleys-story-2624x1720-v01.jpg?itok=WaZ027sj" alt="Arley's story" loading="lazy"/> </picture> </div> </div> <div slot="heading"> <chop-heading clickable-card level-size="lg"> <h3 > <chop-styled-text>A Lifesaving Heart Surgery Before Birth</chop-styled-text> </h3> </chop-heading> </div> <div slot="description"> <div><chop-styled-text><p>Experts from CHOP performed lifesaving fetal open heart surgery to remove a tumor growing on Arley’s heart.</p></chop-styled-text></div> </div> <div slot="cta-link-1"> <chop-cta-link icon-name="chevron-right" link-size="large" link-variant="primary" is-reversed="" > <a href="/arleys-story-fetal-surgery-pericardial-teratoma">Meet Arley</a> </chop-cta-link> 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2200w, /sites/default/files/styles/landscape_150_3x2_2800x1867_2x/public/2024-05/Photo-ALL-ElijahPatino-Patient-2624x1720-v01.jpg?itok=ErwcCG8a 2800w, /sites/default/files/styles/landscape_150_3x2_3200x2133_2x/public/2024-05/Photo-ALL-ElijahPatino-Patient-2624x1720-v01.jpg?itok=mUEfiZ5T 3200w, /sites/default/files/styles/landscape_150_3x2_4000x2667_2x/public/2024-05/Photo-ALL-ElijahPatino-Patient-2624x1720-v01.jpg?itok=iO0-aWOt 4000w" type="image/jpeg" sizes="100vw" width="960" height="640"/> <img width="160" height="107" src="/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/2024-05/Photo-ALL-ElijahPatino-Patient-2624x1720-v01.jpg?itok=B6kXiqg4" alt="Smiling Hispanic boy wearing a purple shirt in the hospital garden" loading="lazy"/> </picture> </div> </div> <div slot="heading"> <chop-heading clickable-card level-size="lg"> <h3 > <chop-styled-text>A Never-Before-Seen Disease, Diagnosed</chop-styled-text> </h3> </chop-heading> </div> <div slot="description"> <div><chop-styled-text><p>CHOP doctors unlock the solution to Elijah’s mysterious illness when they identify a new autoimmune disease.</p></chop-styled-text></div> </div> <div slot="cta-link-1"> <chop-cta-link icon-name="chevron-right" link-size="large" link-variant="primary" > <a href="/stories/never-seen-disease-elijah-s-story">Meet Elijah</a> </chop-cta-link> </div> </chop-feature-card> </div> </chop-column> </chop-grid> <chop-grid class="layout full-width full-width--dynamic relative" background-color="transparent" background-svg="none" content-max-width="full_width" gap-size="" vertical-align="" > <chop-column class="layout__region layout__region--main gap-4 md:gap-y-16" vertical-align="" horizontal-align="" col-span-default="12" col-span-md="12" > <div class="block block-layout_builder block-large_circle_feature block-layout-builder block-inline-blocklarge-circle-feature"> <chop-large-circle-feature> <chop-heading slot="eyebrow" level-size="eyebrow"> <span></span> </chop-heading> <chop-heading slot="heading" level-size="xl"> <h2> <chop-styled-text>Changing the trajectory of children’s health</chop-styled-text> </h2> </chop-heading> <div slot="description"> <chop-styled-text><p>The future of pediatric medicine depends on breakthroughs at the smallest level: by treating diseases with cell and gene therapy. As pioneers of the first FDA-approved cell and gene therapies for children, CHOP is uniquely positioned to bring innovations from our labs quickly and safely to the bedside. Of the more than a dozen cell and gene therapies for pediatric conditions, many were developed with key CHOP contributions. Our teams continue to develop more options for children. CHOP is also a site or sponsor for 47 active clinical trials for cell and gene therapies, each with the potential to tangibly impact the trajectory of children’s health around the world. And CHOP is also committed to creating equitable access to cell and gene therapies for all families that turn to us for care.</p></chop-styled-text> </div> <chop-cta-link slot="cta-link" is-reversed="" link-variant="primary" icon-name="chevron-right"> <a href="/centers-programs/cell-and-gene-therapy-innovations">The future of pediatric medicine</a> </chop-cta-link> <div slot="image"> <div class="media media--type-image media--view-mode-basic-card-larger"> <picture srcset="/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/new-computational-tool-identifies-novel-targets-cancer-immunotherapy-16x9.jpg?itok=bftwTHqE 160w, /sites/default/files/styles/landscape_150_3x2_240x160_1x/public/new-computational-tool-identifies-novel-targets-cancer-immunotherapy-16x9.jpg?itok=-yI_kMT3 240w, /sites/default/files/styles/landscape_150_3x2_320x213_2x/public/new-computational-tool-identifies-novel-targets-cancer-immunotherapy-16x9.jpg?itok=XELhwKSV 320w, 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/sites/default/files/styles/landscape_150_3x2_3200x2133_2x/public/new-computational-tool-identifies-novel-targets-cancer-immunotherapy-16x9.jpg?itok=iNG2DW1Z 3200w, /sites/default/files/styles/landscape_150_3x2_4000x2667_2x/public/new-computational-tool-identifies-novel-targets-cancer-immunotherapy-16x9.jpg?itok=2-L0bXkX 4000w" sizes="(min-width:2000px) 1000px, (min-width:1100px) 50vw, 100vw" width="160" height="107" src="/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/new-computational-tool-identifies-novel-targets-cancer-immunotherapy-16x9.jpg?itok=bftwTHqE" loading="lazy"/> </picture> </div> </div> <div slot="wysiwyg-1"> <div class="paragraph paragraph--type--wysiwyg-card paragraph--view-mode--default w-full"> <chop-wysiwyg-card variation="side-by-side-circle" > <div slot="image"> <div class="media media--type-image media--view-mode-card-image-200x200"> <img src="/sites/default/files/styles/card_image_200x200/public/2024-08/emily-whitehead-celebrates-10-years-cancer-free-CART-featured-square.jpg?itok=fHc9sqSf" width="200" height="200" alt="Emily Whitehead" loading="lazy"/> </div> </div> <chop-heading slot="eyebrow" level-size="eyebrow"> <span></span> </chop-heading> <chop-heading slot="heading" level-size="sm"> <h3> <chop-styled-text>First FDA-approved Cell Therapy</chop-styled-text> </h3> </chop-heading> <div slot="description"> <chop-styled-text><p>CHOP was the first hospital to use cell therapy to treat a child’s cancer. Today at CHOP, more than 500 patients – more than at any other hospital – receive a unique immunotherapy in which their own modified cells fight cancer.</p></chop-styled-text> </div> <chop-cta-link slot="cta-link" link-size="large" link-variant="link" icon-name="chevron-right"> <a href="/news/emily-whitehead-first-pediatric-patient-receive-car-t-cell-therapy-celebrates-cure-10-years">Meet Emily</a> </chop-cta-link> </chop-wysiwyg-card> </div> </div> <div slot="wysiwyg-2"> <div class="paragraph paragraph--type--wysiwyg-card paragraph--view-mode--default w-full"> <chop-wysiwyg-card variation="side-by-side-circle" > <div slot="image"> <div class="media media--type-image media--view-mode-card-image-200x200"> <img src="/sites/default/files/styles/card_image_200x200/public/2024-08/Photo-CGT-HannahReif-AmbassadorPatient-1720x1720-v01.jpg?itok=BZ-lYO94" width="200" height="200" alt="Blonde freckled girl sitting by the window and smiling" loading="lazy"/> </div> </div> <chop-heading slot="eyebrow" level-size="eyebrow"> <span></span> </chop-heading> <chop-heading slot="heading" level-size="sm"> <h3> <chop-styled-text>First FDA-approved Gene Therapy for a Genetic Disease</chop-styled-text> </h3> </chop-heading> <div slot="description"> <chop-styled-text><p>Thanks to a CHOP-developed gene therapy for a devastating retinol disease, a little girl diagnosed with genetic blindness has her sight restored.</p></chop-styled-text> </div> <chop-cta-link slot="cta-link" link-size="large" link-variant="link" icon-name="chevron-right"> <a href="/stories/gene-therapy-inherited-blindness-hannah-s-leber-congenital-amaurosis-story">Meet Hannah</a> </chop-cta-link> </chop-wysiwyg-card> </div> </div> </chop-large-circle-feature> </div> </chop-column> </chop-grid> <chop-grid class="layout two-col two-col--dynamic relative" background-color="transparent" background-svg="none" content-max-width="medium" gap-size="small" vertical-align="top" y-padding="small" x-padding="true" > <chop-column class="layout__region layout__region--main gap-4 md:gap-y-16" vertical-align="top" horizontal-align="left" col-span-default="12" col-span-md="8" > <div class="block block-layout_builder block-basic block-layout-builder block-inline-blockbasic"> <chop-container container-width="full" container-align="left"> <div><chop-styled-text><h2>Gene Therapy for Sickle Cell Disease</h2><p>Sickle cell disease is an inherited blood disorder that often causes debilitating pain and life-threatening complications. Many patients with the disease make dozens of ER visits a year, and must receive regular blood transfusions. And though recent breakthroughs in gene therapy are giving patients with sickle cell new hope – and new options – accessing these therapies can be challenging. In this episode of Breaking Through, cell and gene therapy expert Dr. Stephan Grupp and pediatric hematologist Dr. Alexis Thompson join Madeline to talk about how gene therapy for sickle cell disease can transform patients’ lives. They also discuss what teams at Children’s Hospital of Philadelphia (CHOP) are doing to ensure that these innovative therapies reach the children who need them most.</p><p><a class="btn primary" href="https://breakingthrough.podbean.com/e/gene-therapy-for-sickle-cell-disease/" target="_blank">Listen now on BREAKING THROUGH with Madeline Bell</a></p></chop-styled-text></div> </chop-container> </div> </chop-column> <chop-column class="layout__region layout__region--aside gap-4 md:gap-y-16" vertical-align="top" horizontal-align="left" col-span-default="12" col-span-md="4" > <div class="block block-layout_builder block-basic block-layout-builder block-inline-blockbasic"> <chop-container container-width="full" container-align="left"> <div><chop-styled-text><div class="media media--type-image media--view-mode-default"> <img src="/sites/default/files/styles/large/public/2024-08/breaking-through-cover.jpg?itok=yq5lG52J" width="656" height="656" alt="Breaking Through with Madeline Bell" 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/sites/default/files/styles/landscape_150_3x2_2200x1467_2x/public/gene-therapy-sickle-cell-disease-marie-chantal-s-story-16x9.jpg?itok=hrXpdvIy 2200w, /sites/default/files/styles/landscape_150_3x2_2800x1867_2x/public/gene-therapy-sickle-cell-disease-marie-chantal-s-story-16x9.jpg?itok=SgvVNPeB 2800w, /sites/default/files/styles/landscape_150_3x2_3200x2133_2x/public/gene-therapy-sickle-cell-disease-marie-chantal-s-story-16x9.jpg?itok=UMBuBebn 3200w, /sites/default/files/styles/landscape_150_3x2_4000x2667_2x/public/gene-therapy-sickle-cell-disease-marie-chantal-s-story-16x9.jpg?itok=ApEdRNSt 4000w" type="image/jpeg" sizes="100vw" width="960" height="640"/> <img alt="" width="160" height="107" src="/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/gene-therapy-sickle-cell-disease-marie-chantal-s-story-16x9.jpg?itok=XXajE4xm" loading="lazy"/> </picture> </div> </div> <div slot="heading"> <chop-heading clickable-card level-size="lg"> <h3 > <chop-styled-text>FDA Approves Two Gene Therapies for Sickle Cell Disease</chop-styled-text> </h3> </chop-heading> </div> <div slot="description"> <div><chop-styled-text><p>CHOP has been on the leading-edge of treatment for sickle cell disease – an excruciating illness with no cure – for over a decade. A groundbreaking gene therapy finally provides hope.</p></chop-styled-text></div> </div> <div slot="cta-link-1"> <chop-cta-link icon-name="chevron-right" link-size="large" link-variant="primary" is-reversed="" > <a href="/news/fda-approves-two-gene-therapies-sickle-cell-disease">Meet Marie-Chantal</a> </chop-cta-link> </div> </chop-feature-card> </div> </chop-column> </chop-grid> <chop-grid class="layout full-width full-width--dynamic relative" background-color="transparent" background-svg="none" content-max-width="full_width" gap-size="" vertical-align="" y-padding="small" > <chop-column class="layout__region layout__region--main gap-4 md:gap-y-16" vertical-align="" horizontal-align="" col-span-default="12" col-span-md="12" > <div class="block block-layout_builder block-card_circle_image block-layout-builder block-inline-blockcard-circle-image"> <chop-container container-width="full" background-color="dark_blue" content-align="12" > <chop-small-circle-feature theme-color="dark_blue" content-align="12" > <div slot="image"> <div class="media media--type-image media--view-mode-small-circle-feature"> <picture srcset="/sites/default/files/styles/square_100_160x160_1x/public/sarb-building-16x9-1.jpg?itok=JpEmBu1D 160w, /sites/default/files/styles/square_100_240x240_1x/public/sarb-building-16x9-1.jpg?itok=1Y4m5Ekm 240w, /sites/default/files/styles/square_100_320x320_2x/public/sarb-building-16x9-1.jpg?itok=OCgmRyzg 320w, /sites/default/files/styles/square_100_360x360_1x/public/sarb-building-16x9-1.jpg?itok=bYLHnSxi 360w, /sites/default/files/styles/square_100_480x480_2x/public/sarb-building-16x9-1.jpg?itok=aVCoQakw 480w, /sites/default/files/styles/square_100_640x640_1x/public/sarb-building-16x9-1.jpg?itok=SnA35QUG 640w, /sites/default/files/styles/square_100_720x720_2x/public/sarb-building-16x9-1.jpg?itok=6YnGGsAx 720w, /sites/default/files/styles/square_100_768x768_1x/public/sarb-building-16x9-1.jpg?itok=QN0OyTHF 768w, 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/sites/default/files/styles/square_100_960x960_2x/public/sarb-building-16x9-1.jpg?itok=Hq-bN8Rj 960w, /sites/default/files/styles/square_100_1100x1100_1x/public/sarb-building-16x9-1.jpg?itok=BDgK7YZf 1100w, /sites/default/files/styles/square_100_1280x1280_2x/public/sarb-building-16x9-1.jpg?itok=mgrZyTAB 1280w, /sites/default/files/styles/square_100_1400x1400_1x/public/sarb-building-16x9-1.jpg?itok=aL183aHt 1400w, /sites/default/files/styles/square_100_1536x1536_2x/public/sarb-building-16x9-1.jpg?itok=pk-Oodjm 1536w, /sites/default/files/styles/square_100_1600x1600_1x/public/sarb-building-16x9-1.jpg?itok=PYeO8oz4 1600w, /sites/default/files/styles/square_100_1920x1920_2x/public/sarb-building-16x9-1.jpg?itok=Irn-XJEj 1920w, /sites/default/files/styles/square_100_2000x2000_1x/public/sarb-building-16x9-1.jpg?itok=URBoGAoQ 2000w, /sites/default/files/styles/square_100_2200x2200_2x/public/sarb-building-16x9-1.jpg?itok=_TsZpi9U 2200w, /sites/default/files/styles/square_100_2800x2800_2x/public/sarb-building-16x9-1.jpg?itok=-Lco5SoR 2800w, /sites/default/files/styles/square_100_3200x3200_2x/public/sarb-building-16x9-1.jpg?itok=aYbbjGwi 3200w, /sites/default/files/styles/square_100_4000x4000_2x/public/sarb-building-16x9-1.jpg?itok=rYN2bN22 4000w" sizes="(min-width:2000px) 480px, (min-width:1400px) 24vw, (min-width:1100px) 40vw, 100vw" width="160" height="160" src="/sites/default/files/styles/square_100_160x160_1x/public/sarb-building-16x9-1.jpg?itok=JpEmBu1D" loading="lazy"/> </picture> </div> </div> <div slot="heading"> <chop-heading level-size="lg"> <h3 class="chop-headline headline-lg"> <div>A culture of innovation</div> </h3> </chop-heading> </div> <div slot="description"> <div><chop-styled-text><p>From our expansive physical footprint – including our Care Network, inpatient locations, community hospital affiliations, vast research space and facilities dedicated to treating mental health – to research partnerships that span the globe, we channel resources into innovative spaces and initiatives that elevate the standards of care and encourage an environment of collaboration and discovery. Our 25+ CHOP-funded Frontier Programs are pioneering solutions for complex medical conditions often not available anywhere else in the world; eight are relentlessly searching for curative therapies. These discoveries wouldn’t be possible without our rich bank of biospecimens – the largest of its kind. These biological samples of pediatric DNA will unlock new treatments and cures to save more children’s lives.</p><p> </p><p><em>Coming in 2025 with 350K+ sq. ft. of research space</em></p></chop-styled-text></div> </div> <div slot="cta-link"> <chop-cta-link is-reversed link-variant="primary" icon-name="chevron-right"> <a href="/giving/more-ways-to-give/frontier-programs">Our Frontier Programs</a> </chop-cta-link> </div> </chop-small-circle-feature> </chop-container> </div> </chop-column> </chop-grid> <chop-grid class="layout one-col one-col--dynamic relative" background-color="transparent" background-svg="none" content-max-width="small" gap-size="small" vertical-align="top" y-padding="small" x-padding="true" > <chop-column class="layout__region layout__region--main gap-4 md:gap-y-16" vertical-align="top" horizontal-align="left" col-span-default="12" col-span-md="12" > <div class="block block-layout_builder block-icon_heading block-layout-builder block-inline-blockicon-heading"> <chop-icon-heading variant="default" background-color="transparent" icon-name="person-heart" accent-color="dark_pink" > <chop-heading slot="heading" level-size="lg"> <h2>Relentless advocacy</h2> </chop-heading> <div slot="description"> <div><chop-styled-text><p>At CHOP, we know that some of the biggest challenges in pediatric healthcare are those that face children outside our walls. From supporting our neighbors in local communities to advocating for policy change that will benefit children around the world, we harness our wealth of expertise to collaboratively solve these challenges and transform children’s lives.  </p></chop-styled-text></div> </div> </chop-icon-heading> </div> </chop-column> </chop-grid> <chop-grid class="layout one-col one-col--dynamic relative" background-color="transparent" background-svg="none" content-max-width="medium" gap-size="small" vertical-align="top" y-padding="small" x-padding="true" > <chop-column class="layout__region layout__region--main gap-4 md:gap-y-16" vertical-align="top" horizontal-align="left" col-span-default="12" col-span-md="12" > <div class="block block-layout_builder block-card_collection block-layout-builder block-inline-blockcard-collection"> <chop-card-grid equal-height="" justify-self="center" col-gap="2rem" row-gap="2rem" max-cards="3" unwrap-selector="chop-basic-card"> <div> <chop-column class="gap-y-4 md:gap-y-12" vertical-align="top" horizontal-align="left" col-span-default="12" col-span-md="9" hide-first-jumpnav-jump > <div class="paragraph paragraph--type--basic-card paragraph--view-mode--default w-full"> <chop-basic-card link-href="https://www.cbsnews.com/news/gun-violence-doctors-counsel-patients-firearm-safety-at-home/" link-text=""> <div slot="image"> <div class="media media--type-image media--view-mode-basic-card-larger"> <picture srcset="/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/gun-safety-health-tip-16x9.jpg?itok=rdzh8-KH 160w, /sites/default/files/styles/landscape_150_3x2_240x160_1x/public/gun-safety-health-tip-16x9.jpg?itok=P2UnBPyh 240w, /sites/default/files/styles/landscape_150_3x2_320x213_2x/public/gun-safety-health-tip-16x9.jpg?itok=CwxW-q8g 320w, /sites/default/files/styles/landscape_150_3x2_360x240_1x/public/gun-safety-health-tip-16x9.jpg?itok=Ti11igGp 360w, 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loading="lazy"/> </picture> </div> </div> <div slot="eyebrow"> <chop-heading level-size="eyebrow"><span></span></chop-heading> </div> <div slot="heading"> <chop-heading level-size="sm"> <h2 data="data-jump-nav-exclude"> <chop-styled-text>Guns: The no. 1 killer of kids</chop-styled-text> </h2> </chop-heading> </div> <div slot="description"> <chop-styled-text><p>CHOP not only treats children for trauma caused by the public health crisis of gun violence but has also launched innovative family education and gun lock distribution programs in the community. </p></chop-styled-text> </div> </chop-basic-card> </div> <div class="paragraph paragraph--type--basic-card paragraph--view-mode--default w-full"> <chop-basic-card link-href="https://www.chop.edu/giving/childrens-mental-health-national-emergency" link-text=""> <div slot="image"> <div class="media media--type-image media--view-mode-basic-card-larger"> <picture 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1100w, /sites/default/files/styles/landscape_150_3x2_1280x853_2x/public/how-to-talk-about-mental-health-16x9.jpg?itok=c1bo7o_Q 1280w, /sites/default/files/styles/landscape_150_3x2_1400x933_1x/public/how-to-talk-about-mental-health-16x9.jpg?itok=jGviHbxs 1400w, /sites/default/files/styles/landscape_150_3x2_1536x1024_2x/public/how-to-talk-about-mental-health-16x9.jpg?itok=EdTQgPTa 1536w, /sites/default/files/styles/landscape_150_3x2_1600x1067_1x/public/how-to-talk-about-mental-health-16x9.jpg?itok=dCM9o9-9 1600w, /sites/default/files/styles/landscape_150_3x2_1920x1280_2x/public/how-to-talk-about-mental-health-16x9.jpg?itok=XXd76icp 1920w, /sites/default/files/styles/landscape_150_3x2_2000x1333_1x/public/how-to-talk-about-mental-health-16x9.jpg?itok=ScelHWCc 2000w, /sites/default/files/styles/landscape_150_3x2_2200x1467_2x/public/how-to-talk-about-mental-health-16x9.jpg?itok=dFu_A-o2 2200w, /sites/default/files/styles/landscape_150_3x2_2800x1867_2x/public/how-to-talk-about-mental-health-16x9.jpg?itok=b-XN-jSN 2800w, /sites/default/files/styles/landscape_150_3x2_3200x2133_2x/public/how-to-talk-about-mental-health-16x9.jpg?itok=ShPICFdk 3200w, /sites/default/files/styles/landscape_150_3x2_4000x2667_2x/public/how-to-talk-about-mental-health-16x9.jpg?itok=IVcMI1My 4000w" sizes="(min-width:2000px) 1000px, (min-width:1100px) 50vw, 100vw" width="160" height="107" src="/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/how-to-talk-about-mental-health-16x9.jpg?itok=Ap2_4qRs" loading="lazy"/> </picture> </div> </div> <div slot="eyebrow"> <chop-heading level-size="eyebrow"><span></span></chop-heading> </div> <div slot="heading"> <chop-heading level-size="sm"> <h2 data="data-jump-nav-exclude"> <chop-styled-text>The mental health crisis</chop-styled-text> </h2> </chop-heading> </div> <div slot="description"> <chop-styled-text><p>The United States has never seen a mental health crisis like the one children and teens now face. CHOP is taking an innovative, comprehensive approach to address this crisis head on. </p></chop-styled-text> </div> </chop-basic-card> </div> <div class="paragraph paragraph--type--basic-card paragraph--view-mode--default w-full"> <chop-basic-card link-href="https://www.chop.edu/centers-programs/government-affairs-health-policy-advocacy" link-text=""> <div slot="image"> <div class="media media--type-image media--view-mode-basic-card-larger"> <picture srcset="/sites/default/files/styles/landscape_150_3x2_160x107_1x/public/family-advocacy-day-16x9.jpg?h=87cb9d84&itok=3WTKEuHU 160w, /sites/default/files/styles/landscape_150_3x2_240x160_1x/public/family-advocacy-day-16x9.jpg?h=87cb9d84&itok=6JnOgxcO 240w, /sites/default/files/styles/landscape_150_3x2_320x213_2x/public/family-advocacy-day-16x9.jpg?h=87cb9d84&itok=tgbTGej4 320w, /sites/default/files/styles/landscape_150_3x2_360x240_1x/public/family-advocacy-day-16x9.jpg?h=87cb9d84&itok=EaInB6Nt 360w, 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