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bat6OaIIsKpcqQVmsrl3eAO7Symt4jN02Rh3iw1dFP0QnRlGynwwQOdZS0tAr4I28tSz8eAP7H50RjnfEl4qEA6d6Lpr7q4uP/ocSP9m6uEZOjkRAvZy2U+dFhBt32uOqcHiMA7+CuGrHZ9HfMgnZG2vyqsfBaAYkUKYmsqNB1hb9oGBmJwSHrrMXRGLMNI8MMiKQFBXtKorH2EQQArcR2XVJSATp8B8g2nh0/jH7FtEAUxPr9+Cgl4YgVND70K7UvFbQmOB/07mTeYhBMBgVCHrpPyKiCjHohO+sUeEjPdNR/gWHKa6RYDqyPRT9jfvxuG3UsQwpxxwf30vsRPOLYO2q1NwxiHtd4XKltDW5t+A0TjgcsVKukQ+G5lf85Ia0+f/uKS3JwIu/64hwnzkMEwgY5v88cp/EOYeJoghEmcNdcza5Fei5axHFX+jCyKWY8uF6pkS7PasIcBh7SlvJdRF6dVV3JmMi5ibD79I3hLrAyFv1bT4L1lYiw0LbuZJEiYbLzQSpVUErSicD7pD3puypZOT2bLdarUWSpFwjFPsHY2f0CMqN+kYMR+hxHOjN7Fzk1J8fN9SzRti7b4H0i7oIFyKRqbYj2ZeTGtYPQ8GAdoKtewTDKBjGb1ijZS+K2ftxvgU58+/dAMYhZqdYk7LDJrxbAr6JLwmlTHtFmeUZj8pnXbZKmACJHswer1yv5a8cQWjiMW4clPnwDAZLmC14TRYRD6c0UUqY7sPZqcBl3yaLBqgNAzKTxv2zCtDlVjtpF2KDOly/zE2T6odzgTxZ8+XJpmG+Se0xikWwkAEle8h/9tcjpKSd2FuHgQy47mMQEmrmyP8rEKvgWk5+8xK2i+YX+3ERj6UXvHnOaGNzYa8w/25+AXmDyxt3cJnvXPiK86e+dm12Oou1f0fStv0uZx+WwOWTv37hByp95r30WWHsAJiuvs/2a4FPZIrNkz2aSLlRrETl9elSI7wFAWCHqKvH7UIjhQ4Qjs1bIaaUi2Gi6tMpMaaoqQp8WjMhNHY+u9iCzwUgNwwaa3A3SsRuYQCPAOjQkbAR2+52AyqJviw//eRKP5GYxuDyMVXl0XFRtC42UwFppDQxdYD7C3Hn+Q8Tq7syUIs9yxZMuoW8TMbOE/T0uHt+ijJvSxbR5YlsuWaunguiR+XIB+8oT8Wbqh+7RJaJoPBmpWdtX85TwIVzAudN/pXwsV/lg0ftNt5J+6ZHHzDEEOXcfkc4v8K00dcNIlxxtnRihjrTn/GMHEx2aCTJN2g14/2sy5hXkClsL5/zYJsR9saMh/0IpBwmoPkWVyGZeddNcRtEiuimijFp4vcwC4TRr8gly1WyYzKkBEiH6TBw3XMeMFV2FSMggUHSRaRVnFRJC0MDr3TPL3rUPPl2Lzzu3VZm0SsAUsTBQ1iJaoyRh47TSwBwLJPraErX93v/UVsttX5Gsz3LmqD3AcKn9BIS6zc0wx6dgBqskNcT60xkiWS//bGszqrSGOijKzXYs6MNF++RWR+I7eDeyV7uSj+IfS/1VBpOsMdia7QqgdEa+x/NLUX7UP17gLPFVUuFk9z7fOQA+UriWqBv9VCvsa+zDfs6BM9MLJKrAGkffofCm+LcNr4oWA92sKZqHu20fGBm3DEPXYSbxiffmVZ9JHBFO3wMK/9jpXe6BKQzKU6y6jtwn795YFrN9bytEVHOKC+RqClj+tczXX/ea3DqLdp9BwLOL8ErvH7Miyy2UZwFKHW+0evNeDq5v/fD1nerQDwhPZoTacSw9u8SRfXE9Kg8JW/9t8/1AcLDA7CE/GNLsQ79+gRFyuQEl4jvwtIzB8riMmQDF0BONnNAYzgHTiELB+UKmVnn17nUNQEZQ/k5XjWSisacrMZWa1Od0xnVmvp+Vg2UIHxYsLgQdCBNvgCuB5V6ZrWict7BxT76jcUhfbDmw5WAU1v4iGlcZ5ZuFz0ljLG+reCHVUJLfhT+DX2K1ZC8SMq2omy4U3NlhOqeoG3wds8/USWCr+rsTkq4f0OukJlQxee43Ux6IhJOOU5PnXk98lqRQkvGfC2Mhv9ER120LOHSoCRT5FC+giO3uDaCyZtrGWC8XEKweYMJTtdm9hbh5prtdsUAgv77eHnOWQYHr4KhfpxXSPM7QPJfRNJZXS+WrDvOiivF53TggbZqniNuKJ+lQqHzsii5VTc0hvrS8tbkK2/hPPb2A0cJ1k5/gYvTUGYqG3JRW6gUMwUj0Hq1MSttO+KJxZOFooGL1+v5sjHw2L08Bq01W1VDZegk/gSccCqA0Ve1tSDZu6qMVUh/0uZS/Hfap9ESINISlnPMCfL2s4pYn+qkgO8MLfJfX1ElNpMG76xyfacLSP618RocztX5oMNmPG79LCxiS4nIpSyutaw9GgIm56qEFgnKxJ38rBqTFZ2aO+Kogm6Yx+4Sz+M9fGMxf/uwh4WVoxKl/tP+Bj3Q+0RZu3nWdTF3G4scE3hxVGcNOCyP38J86slShrDN5gBmkJWg6zUvbTiwYjxt2FtqhulGcs+rJr5F90wFEAsmh+iHsHkiDAtHc+Gh19YheXzrXcwUXp96z4wDQURDKIjWjofAsgcHfGc/RRp4M2maXhEqZBN3k7OrNC11SEBlVHPlOcKeuOqMBHIqnSi6otup+YqD37gt4Qn+qyNAUaew3ByibxDrMQBKahjIaIUFR09ToBibbueH1nSYSioacKU3UftPwVOBAh+SO7iO04RD612e7QChZqE9VrPMvLAtUvZ+QYFiOky03zEeUaXpHj8a1EI2cOjs39YQ7qvdX240sn0suanzyRZRAV60P5cPtmq5rcBCy89h5HKhMIKgPkexlqU7YJJhjxF8de+a+LaIo96bMjbXD6wsVK3MRvaogyWYLbqx2qjZ+oodl3I0xh46Y+UWagH0VmeyW6O1F9GJvcebB2LpqGn/wImTFasLxmAXQLBNWOsHEa014XMTO1NLvUpuIXI8A7DWfkS9pFD6JKTeBDZ+yPTjHS9t2CBrzm0+8ilJulDEly438ouhESMmG2b84+RG6Mebc/xDhp2hGBn99oieIGyfAoijwkxC4SW1pUMUv/aHjR9sZqxd6k7c7+HUshM40N37PYapL/EswBT8UbF+66gQkOUEYO9n8j8JgvtRsA0JaBtz+gllX7svLveXjQRJlHE5KioEUruZH7pkfagokxqTXBPduCGOtq6WhJaXlAhbfIfuFdwsnTksJ7roryiYzvBx4iSq0uLFG9ncVg/yTLYrh169lumGR8vh88J4tHeTFQJ1LZUHbtNHaEKqDx94/ljdw9wddS6lSpIxloVwnet2HSGPdas10fKWwEz8ka/Q2jEgVyiSHMuN7t95j9hk3mYehoO4EuUJkHa8giRSN6aGC/5vyB7aRhKsvWtgkKw+rKoeBL4/HHY1wjH0fi8a62q+nvFUlrx1qloR8euJXCn04f1H3p4Y8R5ZEhknykBXjv92wjlV20un+AB60GWEtKcEiDmFqDREK4LCQpaF3RlBQPMO4qubq6cLoJeJ/mzEi2JIkA83a5JMLXmtNvAOYAObphtH+2vRq/s8j+KC7tKfiryETipp0noOoCKfPMNt9bYjTO4Kt+PDru1rNNGWEzJjFRSew/dJ3W86zaOz5GAXTdaupggyhcr0rBeMxenG/M0W8Dp0ADrjus2fWcxwx/eBsZ8OVRzKqeWCHytUCn/iwJfk0xezpBdgDYL8l/NSn2gfe7bSv7QTKoJC+TJCJmcZ8n1uVCMJjFVK3I0R80Vhcy2GgfIrdvxrDrIrQ//n2dhoi9pQ/WMf7DPsyjviT4z6pnHyZQfPSqGWtamfFUopAi5xZS7Pyt9wy7N7OPeaocfw7HHct7ThKrPdEQkCoWvwjSc1KOaPjVmg5vZqyNokhHDB7TNBfvJNUtNpf1L6WN1oMo8VVys5+h5FlWi3t0TD74dW/Ge85Y9Xa326lO+OnKu+jaYimwKmixxIZVDwjAtd3uhxH2vNesppVPCAdsFK46oIPoaK0RayxWhJXDEj61q1RBhdctYx3JmCD3Ma8hrWYkl2wd1CpZnYe4g6U9hoH8UqFzqMHowK+2Tk7UN4gLiqk6iH/V9s0LxBoD2LzgieYjybWtmMNqzPB+H92+TRbulIxV5wC7E5C5LWN3fSh3o15JsDgzb7aoKUDq6SCpU/+HCFSMZc4J/5vgY5qQDEv84EA5zLE5y06YyhdiD8K7B4g1XXXpVe2zocOkweRWQgJJuq3wdyBKqpcc0SI60j4UGPQcaCqKmBBHQ5a1r60Q7gK+F2By16LTAtjr0wbUgd7MM4m1msDF00zFhGTmS6dsnN4OT3zKKT8HIfRAIFZrhD4GyxxEo6FLl+39Hfir/QFrt3bF+2WxzmUP2ht9fhy0IeNgQkq56MIYk7YFD5oXlHAkZs1LEWDNqn7FlkQyKjFvkKh4IsiJPCPAXL1drMunTEATwOnRTeUl08BBmKQHlWhcCVKhUlP+DhkkEDFXf5lNw/BPhJqjixM2r8dr5j7OofbVtURQxp6A/FUno4zEePM1FYiKapfYHvD49+ldFHsDhUlw/UypCohwkFucVcD54TqSy+HPc2Z+mOg7Xu79vpIz9a8KjTETRDgI3YqfbMxAa38h49eb6ygVAo/97zOGu6ivh2HYwTy+r9pbHZg2OMtosiHfd1mdBVVnwLimPeUx6rNyFktMYJd6Ndkfwd8M5pfk9G1/8UviJYFf0Z+EK5iYzgT+JV2IqpmLRV7JeWqAh6JtiRqnS45Oqpfh+qPzG1yIHy7/2gVF3j2KPyBmoo1DquKDuR3rq4oeOAOvfZ1Lmjz+AC3tuCbbinBmGgy0GEaiq2OKc4SvUibspDwignKDDN+VNIZEEYbAvT/PWIKRVzjOMWqOvlSuwffjzYouxw790LjBm/T8haLurXfBilNVFRlRnTPlrLpYW9ISLu1FNCHJ6FmfxyaGyg9ujjbkJbTZxmJirTgL6F87ig99hpbvJXX31daRbugxrTZ1mNDl1F0tFa0VpusXb3L3c3i47zmdMFu1ORRosKKgLNGRBKJ8Vqt9KtX2mhLaWUPd1R9+hBFJf/mXgMLyPDDHkqxo0jKwiRoG7x9JjbRowtpoGM3yNAJbcjOpdQM/QTn9C7yLj2z9+mUH9J/1E+Lw1vkSi66/C3cz2+3Z4LzRztlpIC2WIquGON/DYpvcVrCpoijDWUYAPuRHlaioUTVKxJyLey3FwCIjVnCQkANyA5dqaLJx723OsQ/X5qqgB9vG2Zq5c9uWXL7+lXWaGHvCbM6FLsmVxLpn2yPdcnz9lxz/R1OxLUKVLMDvWWsf62Ok6Mr/33lvgSu9qkGShhvz72sx9idtGA6QApfmGUOU228bS+d6v5ViS+cX80wVjD6BwGQUr7kbGcecKQk7p/5dcjS24AS8RHjvg3WYSmX7ruSfDY9rhFMisooZ/X7KQur8Tm7bNqdie211dmDeaNoVim46rVUYF6iV2goPHmoibvqViijYr6Zt756TXJpu+f7vbf+4PhFpe1YnqJHOgB1Mf3NRxq2rYh0t/7q5T41qiAbAtCtsES/NMMlsowi0zfg3uL0dz6k+RtwLvMoGCrsLUhifIQxtD7Z9Bkf/e751JptLp6xJXyV7V8UhKDU9PLXbFJnNNQc/TLU+Weq2xsNvmSLgIVZD9mJHNy3tHfy6xlqoybnuuy3PHNaVPnnKWe3EcKA+k337faX27hd088n/7/Pgr4asZL+IxWwLmq/+8x/AxEvEni8uBGOW9C9GtLRF0DtB5VbbB7RPWbpbkjAjbf+8HQfuXddvLmxSQJd+z7zj1Ay34etgw+oFyD55ImPniUozt26F2k9oS/AVfkaMpKyDhZNOiVdOVM0WahcGVy4kX6JeAC7YtTRVK4tYbxFR8dSXI6SIdVRHaJiGWYR3bgXA0GH/SCCJyT5iciz26lXvf7VGZlCKNPGtZB+Cz6aHprZEMeJfE3cfiRF44LKzikpyBV9gqYK+8HHpMbgujvlufkHw9bSO89GoDa3RFAYtFb2S71/lJcb9QoBz5c6qovCxxP68Oe4fmluXGSbakqVWWxEQZerwBx0UTqnP0ExNUlRx2lYrSPsSvYRC3XhHAimUhMSzaznbwKhaK2j+MNF7oaYYYI1ABZH2CFbogynvY2H33nTlRLVrmycZl0HhIlgpm87E25qYyTQ7QmhOKXC+geIQm+vaa62viYjLruSPgLzU3DT1LWPvMh2o8FS5rb8iVfsVfj9NFZUOlO3IReMcqy+tNphcaOivlEMHFMLUvrMhF/xkIG1TuIu8fFptdL6LUxJcuTIMoyDjxBcd0sSFE+b0GEZinvunZtiixl/UbtYpvdEnEedSpqtRTo4NsxCQ7SX1yVf+l+exQEY6WSNS6FhNL7mIc2pt4mRMklIS7WIcYeoRRfumT8eE8kXxs6c2b+tzTM1pi+kp+EZIZ0J96ZSIIg1RR4jXMfl7A/ZKy+oLAbQzXUorYI2356Mmgd9DpydcBhKFS2qcoi6n9S9X73GgtQ9DY5uzHz34dKn4ikmck+yAvijKr9y4QqKGhPBbYKA85JJLhIG/DcWaLxPJPTED0CRpKu53/ML7I9cyfv4sVXTusdYlgPlb7oP5TT/DCtsZUkygnt43jULduLSO50X6tEH3jf3WMZx4hV39oljyIDL6B0KeAxxIINtJcSLcFLEV8SEfMgP+TC96IsBgRVMObWHMDMS2Tn6z7oqPunlyaTESgJgCMyWT7wrRLUJDca41W3uTdNwZjdvMiQaCNnM1yStlht43vlGGZUmUeD681DyEXUaeI4PZoXHw9ub71r1EfEpa1TeA0MQSW7ycjxuPOJgMPSsmWb3jv4IfSMzswm5nQPj6Pq6S8wkaiqrK8ZG/uVPGYMlpYO0WC+N1o1W73pAn0xMiosMIBRkYNzPzcIuwCRFww8tPJj29SqZwSb9bx64vxS1tZM54xNStR+dLNiamUYM+HxAiDW1yOpWSFEddhF27d2JYlgcdr04zYXKauXQbGaogxLP4qKci1q81VuJWMw3WTyr0HCF07w8TAP7hUn/XixkLmSuA2B8o1bIvQvh2T55OwDPe4LTz/Cfr0ifqCjFUoH5HZzJYeThKEzpxfmhrYV5NLqDFdeqE08Xy5WcxPsejLHPajL7ynMynriCtcJENlHcunH5z6Nqtxm/+MTlw9iAYOJQsi38Mu0FfDTSOPl/qCT5nwN6MON9kXMhUX54MDaekeTuD1K1hUtBohKSgqXnORwmWDjjoMI5vuKIsvmPEHwunyB6g+VXHRTXSs3mmoTsgrQZhZ4a7n6SGaf+PvMf/cSbN4EEZ6B4KnFP43rNA+SLgyBGejUHRyoRvzz2K2DSnkt7kqg2JpRvaIvEA7Sd/XmAREqWaNiSEZH+WgqKRnP06YfdtRfZGfMNhyTKQuiVJf/aaXKrxOKHsUvgjrh2lGdncwXfBLS8sTgiauWWx981zjdLIf2ZChIak2msvPdQ5/45nt9q03oBm+Y6GfWgFdUZ6KPhpejsp4AYpKJPJpov6fFlPcT7YzWslPTj5TMJrQyGk/YiUnG0r0Iqf+vMxlV8gPJa6ViY8qMbmpl/v+cNt1EX1yBWig/8g87BRez46G6wBYM1BQ1lFiLyv6URJvGaFKRo84kkiopxdmhEZoBOao9Way97VJI3SBedLyF6YW2ZSL7N2VusrHCvNO5QR8aeQnKCvpwtrwFdKHkHBZ40B4gi8AT8Ti/ByNHxSvX+JzpHlG5wXJnikf7Q7EU4rD2By5WCvMEge4pWlAaCIOexG/Mis8l/rYTs2NwDKEAZ9Hm/vgDiMYCvYud0m/y1kwGKUXnOr89++tCFf1moG3pm+AUeBHxx7GhO4ZQE8se63+ezpa6Ledg0XDEgHWDy3nZXzV/j4dDyB80KKsgz4v+sxh1irhRg3B2sPKm7mZR9/XFh+ecd9jbSPyV+euK1FmGGL0vfGSqqVKNm4/GJ1W1+FIkSSx8HkMhur1ndYul2+WDO1ZV7Gr9iqKrpdSowbGjjxNXWTy/uo8jz3qURVXWN5KH4M45jIvq1gbdIjw/HYrGPEVYNuyn/IZGq+5+pnabqJQuFRTemBXYeTBSPx/JjlQpWVIDVVB9y6L/VOeU1QvKE1rs6svUYdWq11qXxMXXiC34Uu3qLA31C9Qx7MF2Depkef28YmZhIQJMUgkTHcSYN0S143Cz4QRJnt7OTiS3boMVfd4p5qfZUZISsxkUn0o5md630OjORbCLJHWFuzeO+RKuny1nGu86xoYEFCDYH+bbaktUKDfxFEjQ+qvcR3RvNkv82fjXSgt+5eSY3OW+yVr/hCAB6ggLFNU8FHTFjZPmrKDH7LSErhjFJFuhfNu+eQK0LuE/BmmrVpXvE4Y+qfWW3GvjNg5dh2v8lqwZVMELjfnufd0GY7PTr9v++x+8aAZnYazV5IKW98an5yvYEsnfHx7AWeUHYT2Iu6O6wosv5iuvFCBN+3WdgCsByTE9hT9wIUXijArO7RWiYO8M4fSVYd/A79GlDo/P4ouoicySfqe06Bzb3GJf4Y3Xbet6hE+uZaFi1wY8+JehzfLywZZxwCrKtET13ADL/sBJlsYVQPLyvy+GqpYP8F5DDFL31Ht8DIOXfvrHJ6WP//LQqAzr7JryYaEv/TmIQfR8vpH9J0q7WjcjdFPCdtrEZKUA29ewHHnP7dcf0ZAvOORnUlfkckP/sFZDdOalnjlriBAoJUtPYz+p3Hxgoks45IFw+zYBfMNdpMKmB3M8eUO+nmwHgrxGXddR8YHg7h7kWGcQ/NvqsmERaNfWdqwlSB0gzoKzkC5A09uYgUxmfb7TZneQHo3ojCjq26PzVVHRGHUbAHVWpinV0wuTBrtbInNiQzum6MvtXguNHI/QXYmbNj2fi3Ar9aR7bCreZnxyEOqy37A3awbXpIKgHonZiSBphaB++q4IQkoVmCwGE/Pfe554jvpOdpmAavydftWmkxfVlZdZ7g3UhBTnFQc7qH0q7xP+mnGHstK+XCswAVweV4whrtKQgNLCdgWD41uyei3woPASH1pc4HpNrxcSKv/VqW6PcfCo7cG/PCoDgcuGQh04Zbk0i7PzJAq+/aG+gVPwI/FUZcRkMMq1cMpNW8BM60kf+qCAYr8JsT9/wjeOW3+fP98dMkHNbdUhOlM9SfbliRv6yegVmpVtxp0EFMEWonwsDnnETabpyLkC719UmKttzAKgYg7vppp/g2imDBih7ORsafgIQ6NcK4SsWSuMR8h/5RCnYikPFy5dEvaTxNXtVVUyfQp0uimsje4YciaXXcZMzL2+qLbs6yhDy9pizpFLdx8jR+c2z5BW+yUh2wFjPtlpjT34w2mc5vzDXoyBpmAMhyHoFfa7BQrzlrH3sOBr1zxFmEET+/rfoIrCgseNMl0SqJ5tsvi6qb3psqwLy5+WbcQjpyA+vA3a+jRFOcQZjyVJGQSvfJrSezlVwy4IXuBPiVFu3wxpptsZHUZ9sz5vZS9ljdI/2DDCPc8UWkiYJJOg0y0DQuiJN5VUvCMx75rOc/yMBiD9q5BTQDPSKItMYRhph6HNuK/wOlfLDKsjMLBAZjYTI65HZpQljIemGD8aQywfrunNKPzgn7vqujf/RYDIHJZ4TXUYHVk7u6mLrNwtoIRBgsv9mGQszdZ7QP79QzfQbBHEduB1sfaf0Zsf5+ReSv3iJKoTVg8OlOajk74L2KMBzG2uxaeh8OeULMtQlkRh1vM0aNwfaASe0Yfo3gXPBhZRnuNvDGfIa3J55WCsXQQCcIV1jHWBrjOCWwPGrxS66VJKsIJdBmIjo0c2DkL2KNQo6JFXnlrmb6O2ca4E7WvEruCKFF5YtymqDl4HB44hZ18U6SFKEReMwOkgVXza4+uVEeU0MJ7HI9BigsZMfGdKbVquJgkVBtjoynZbmj9yLNSuXeD61AEcKtnYe4Mkxqavec1IfQ/YBGrXYrwx4YY25xdECUueoMbpcDFMcDLZ70Og07juC9SMTXJmPYBFnSLFZUZrTmr4ZSx90tP86uzgy9P1C++gO4V277KZfxbd5UcrHGa0rA/+GV9w+wRMEVjDfL3/CvoHSTTB9cwHi4TL8mmvFsgoFYZINsUeQvrS3N99G79KlVTu17XfoyTa8iWJk4xEUTra1DOGwiq2c9dXmhzEyS3P12cJ4q82/WQn3qix7TCXDfkqoZz5iGDz/bx1PHfdD0pDayUT/5Hbxzh3qZxaffsqbADIUC5W8rQdGwLIO+7ebTeQASAUG4uJAAG2GkUE/mh58epuroPhtQ3UDFmvHS0RoL+GBsDGQWj5wp2pCdBPMb+8GVfdL6FCttU6CcxNcCatvbYPXQy+V7uD0vO7UxCwS6HH0UKXL9BfctYCmPF4Bco7xxj4RsO+P1eJyFAnX+6+oOLVTVd0cUoA90Hm0YWDSPkgJPts9qOLH0zCiZu8y2KOLFPwIP1FUmZs+yPtjsfQ4qsFcP8JJLiWCPDhg3NsWPnVJU7YdH02RX3/f7+Sbp71Dsbm2Yza3tc2cCbwI+A8NXweOaxkK6FaCgohIvN2yHTmdbgtgn20n/ys3k3nORDgrRBM0JtH5+cqQxpGf9Uu18yiTTPWQHHCICda3ylNMHfF7r+rX7AI4JcoIuP3/TYqD74TiQ+KMq3stFxTRqRRzwUQQgM1hrnrcbD0p5OYd1UNMt/93y13EjdZU46tDez3yB2U9I1M1UZPF9FuDUBtd6mZjkvbyXm0dFSHhddWrKcLF4dsq6eYM3KWod90l/iqJPb18GaNb3QPRKXMFNv/VupgyyeCzNks9HjHA1dwRQDXlx2sCKvPgvj5r/sEL/lp1VnjbYNU9h1iCuOWREvKK7aqmwlQrAm2z6gZAvyrpoLxLUKGBXhYnO4rU/S3VNdutHo/W8QHKZCOz0rairG2G0evZOKBykfKBUb+B7sShmx1MzL/J9TJ6fJaw83EbybkO+jNLDEZggS5L/WHhJuuzi6E+xKb86XaSUyIGHGLXMm1u3bbG4Z1HosH6uNELKgJwLfhcIzYo6j6CFdKL1tB+hp78VYnsk+g22USy1P2Kpq5XJWBewE3RIhes1/kfXlqb7bMNx51bUgR+5sYz9Cm9YsFlEzKZ/a2dn9Mu/421C/DOiTr4WwIR2r2j5e1lMMbxurwyk0gIaaNTqEf+H0oXBwfbCWY763JcMg6Lg383jVLDOX1M21UQKYvdY/0v1H9U/rO8XliLqIWnKBQJj0DJswYIBWZ3pLPQS5zLMLxdt37bIHnhI98E8+SaO39y2WMuNbhwXFNBVsKltbpvPoQJiy73fWhtsFs+ZIHviuZ+yplrZWtQHWwCIqNWr85LABd5qGZRbcHImiwRJlIsMxZ7CC2SO/oVs9zH3+jb47nFzmWY6IJWYEF0w0osV4yGhwGNfeRVsay+kcgV/HTWic22tqKPiZwCYUtk4QhV1fOkkvbdGtlE8Q5+ODHBmAmIlD5IogaLrCbQnM+4VALZiErNt/fNOjg9H+NZh2/n/3L4ZI5Rem3XPJZKeJ8sCzpcmVab5DL5LC+K1AkVuMmAn3TPJ3Bij4pc4ebxdc2ZDraVGgkh4G4TJZNlmQHlMgE6JP9tp4wST3Hzzu5h4z7CQ3fotF1rSfGineubJ9sh+FaOyeU/2npX2xlhY0zTMgUs2ZithxULj0rzT1AD/Q6ayXdf/172OmbME/p+Jo2w/whQo1zSVjPxBlbUKZFr5u0G6ZpzbmWNgF8bcxEqrcpIEfxRClTEyXUueLVoIslYWDAkisbvYLcW6cjA82SMmSCnOH25O53fF/pZQNPRK/mgWi7ubB0gbiutjMPQiDQMkVcE3yNsb42S3DzasWtEpV0ZDGo54czx0UpEHv+SpC+/pYhQKhpw9rkojZsntli4pzA6p9JitXGe7NQuYAKC0ynRd394VbR5WWcfGRm1Subh3H6ihMQltOaaUBGR7ghfdIVkG07aPcULSnKbpN2xRw/KjoacQ5W9M1stOsUU9tRZ7i0oCm2uD5cjYnC0L3d336+nDJbVOwa200+cemlHFC1RYrbmaiZHKyUBogIHxIKi24tG8iS06yadMzZ+LbSC1g1ikUyarGvxpJaBFX23KsGS9OwTFgNJdh/S1DNDgIZhQ3Sg/Ng6mvjRV+tjl2OBA/NWMelByx2gihlQwPR3WBxXKYSHtXm2Bc9KKnvAOkUgqvNmE59FYOH8/UMogFmebOVc/yejk5O+3Lf16X9lVRrZ93nVY5QMa06XoAnbl56Sm00l4hARD82war7qEgpUg5yvn5odWpG/SJptjqkvPFgbwYZPVJgbK2WJ7CPIptJ74mzFrxvf1MmBpPoU03aZ7Fk73r1KtQAdBC3nVeVBXZjpducBjAygfBSIRwNELgZK9/DQTtYEQbHV07493tatKKZ2JJ7zZmTCcrqJDiCCnoBQSXWrFKevPQC9vPNkACQe9XtOok5T0V0p7BdpENiCWpKPKRcScqvs811ljdY/kIpX/EQ/kaCzyspUjTOdamkGbtnHAG/XRV4dpuKnf8FZFmFwbHOSavyIJq18xkWDf31w7MwbifSxxtt6Opr8ADm5ExNnYpZ2CatHDYnVKlx7hGMn7g/RwnDdtAUglCWt1StPWxQQ8I+QxSYeHv8YY4RvfhZTlDLe2RG/cCNcORGueOp03ZmBL0aOx6LJSZIsrcF1ztso4E3YnXJtE8frFO7ueHbAUYqgTivSrZdq0l0b1RkAS5DeSC9KwjgQzluzb4Nr4LgFAl5v9bKXdpUrSPYpMj/cC6T3HhIRjIhz7Je75eV/uXhJ6MTGWsCcuDoISxU+Y886CUfn2B0WUjWQ+oHtwK+1eL287yU0FB2i63n6TFxMfsB6JdTFbHfPauWOtY0AlTP/z/MBK7bhKXbRQgEQ7Zf4ecmfnd6sxkbMHLeVhWumkFSb8OVaLQhFiZmE1Wb3bagBcqTM/L9y9mvLcLVQSCvGRPM50hqwR4P4ZI6kN3TaMSLUTrDBZM5ai0rwuzPePkqM2ICOI1nc56HdGq0q+sL2+csCD9VMp9daTYqnTvVA5Jd1WI3aq3NXAxre/sGFUIuQGM+LiNbhE7xGWy4IBEuA8aYFNq2WjRUAGqp1H0qNK1OR824xzLRRPzadf2GQRTiJmx5C9xkVRYJ1234XD/8zy5/xXSDPCrpCSF1ae+KUNbhL+o4LuUPmUBjKzGVvwEKQpXCTa2SdFjgnFMoUPt6V3zhrGQS/XK6EvdJP+5Vym1mBowiPM+JQrKNBwp30b3NZCN1CqzvDfqatVJF3t5vpTsBcniYFunklP/3n7ejhl5W29exDsfNa/ELQXaaDKVVTyY1rFZw+G/fRulLVAIlfZIPQCVAD6YljjSSP223MNocz7NjSEDRs0uKlwTDW+/CZdFonD8HL6OVj5PT4oQ4qZRum31FKSlcLXw9c315P/PQC5GkIkDq/TVY48n92ZYRPUenig0o3TYzDGHXr8a6sEqq3Lc9MOrsjac1HSYDxtFjYq2TgYfXzgurLuAXq41XzqirthVQUXyE0L9gL3xMfLhQqRzfn+C/9I8lrT1JGFOnfFD/cQnp8ZF0ico/gV6K3yGJBJtU5HOnLszeTI4Oe9wYFtESCwwE5FVuMxR8oRGTP68Hb/Y/nDGlC7GprvVJDzbMMj4ckioX6HApf4kE837ukKhtFrIFksgYmeuRUfauVtg0BRyqU3TOOXvHeAQrpu/1Pb+wp82WjJxipHPHmt/+6Q1NlpxwkowgQgv29K8NzLPST3pboeb5D4gB+Hvi0ZVzTOWIU+tbUCk7QooBGiTR0gJprEA6RqyVhv0ZnFFsS+51ChTPJ4+oWkWJJhoHi13t3nVfpAijLm1tukcUQuPEd4S5smTaR7Jxe1qmnhVf8erPKWthGsp9Z7QQPeECyR3zkp/WQgt5oW+uu1FlvXKCasJs3+ap1fVGGrH0RqJvbHVCLfkuQHSxehjsnEVtQADIqq//AHL4nmFVWVJIqoxqzZkXB1vWR9ptBlrcc5niI0+wXLCXJMg01hLLGbyJovDd4o4AV+joJ1yqvY+ZBesffj3jHfGZlzhnMvJ5dWCxHUtlJ/d+rmeD5M/i3R/pJC1/NrcIpds7weyA9By/NhB1wtQe8m0zQJT4v50n8DqN7Br1L6qpaDfyZnc4rAGODbM2wCErA28gmR9tykjxGXngdjN2Gszd3Y/wDmg2mXAnaQw09n9gYv6s4PG+jU+UkCakAm+qMYQdgPm/Bal/GyhEU6cjE3bH2jFcYNr9W7cSwOFdafbS4VvKAjLVI6h8Z39iODSMLtDVmY0blQ/O7LpOAZi90U+PmOv5DjePUFAw+2Y3alTJQVd0W/rqjJzsu6Dp6ARw/QH7H33RYVLU/+AaBhZ4V0BiiOEsuORatekp1hKDbjlZhpifb4g0V1Ln1IuHOa0hFRh7mcUwgI3r36fsG5TfRWPHmW4Z+UbcX2RN3+HjrF0IXksIYmMZFlL2ld7HNb7t45+0KSOsMEzgy1Ku2Z+/cexlHnXAicvpT9NbCKr1nFWyk/a4z0YJTrt1+GwNY1kGUpasHFYmPW0Tjx9YrkMxjYtGc6V404DRrZIEpxYRyfRGV/IDHBByDg0nt61aSwYeMQjAUE+gvMnPRZqCqASh0Oko7FjtMnL81cNLlDUEUDlRADULqKBvQxAUIeeA2wItNEJs/DfLmNoCYVDW0mIVjZpYe5ctLTWCbzg+4Mlr4t/xVoboNywBPivq6Fj0l2LvXXWcL010slufxVzlnIPhT0N8eHrMiRsNASZ2kG/KVfOMKXXIRTiR/w7kMPUa59vAx1QVrNvdhysyXVDprkDjt3GjYxuB7nt/Q7JGS6Go7uPYGdT4AwwG9tZy53KhWpelV+Wd3ZXHRtByhUERh6g5ZS4JBI1Q61DuZx0m5aRMuqf3nSCBQA7UKRc/0khDWIPFJCJHVTX7FJTFXH+zmvZfuoQDc4q6GDhM6ghrJQN5EkLncdP5rIHg6XyssfrOq86TFEaS7db84BM27B+2p33eJzf1lJOwo7HdwmtNqMUiAK8wVe9obz3jaj0yIpGJjxOsFPppXjXtE+48VK+xuK+nfCS0HQv8PK7NPj3k4ugGJdVVa+jpkwyvKiUfl8WA4slUphpvRXMW1j1TtJbctIUuKkJFfkYyZ+5HHjFPFE4wcQgRhpuHBd1hfCTzqdEiZ8uq7dAgx8Gcu4rJDKgQ3Vk6XVxRhW2g5A4kdkkEWFsZ+qTKXMOdEtx3SPbLI2kk5zr6biK9o4jPh9Ho9Izce0lM/4INcf942QGPt2NJg7xPZgmRNtG4kubq5uCWsRAMXPfXY/GuIXjXZs8MidUNR7XYhev4JmjfR3tZpUgCe/p0LJ34lyVz3Zr8ILsD7XvYy9+Es+9rpk6HnmhfU9Uw9kaC1/7KbccnxZF0sW2CVVuyr11yV3WQTM/Eqk5DfVIhEzy6yeGKaJzFed+YrSLXXpOeQBq8ipfKTPUjPpPHU7DxGdtyK39UocPEp08F3jzm3svqwYZrSoXHbxySqsjVNPkhfkBQH48JxV2cw+D/HzKdDONZ/Ztj3z0CwRGY0DoWvLgL8ZkRfcwCXqugQH2/PzK5Bqy+R6ddMRk/tPXTnlSN0olccwYyClbSgEiOETtVgT2lr1G1Z0w/iF76DALuYglbU3KM5etJPcj2YVQ359RXfB0v4v7rCROcki30VyVV93gIHDiUELcXVFD2kLHOFOjbKfTo8pj8YNf0DN1uk7Ro0oE6Pq+DXF0nplfWWRYApqvjxOtuf/MXIUhm3w3+2DOl7ONU3AiBL8NzV+AeKLYANGQihrQn8Bcl3ocgRAQDkI2FgqiQdjicUEdceiWfWFoHsxDuQxTP1Z2Us2EYuv4dPhgBm9HMmWFXp6nwAxZ9Fh+2jyYyZGHfnt3hceQDUGqp2jSxWF+/GVmGgp1DJPqNbl2m7gfHXdT86rzxnei0ZrfZijabgldvnDuYNOC5qKlNi5uQle4uBQvM+je/sNk9fTN9J46yx27KhcPF2aBvEJIoN5kpAv5j0qStqe5Yw758vIa5ElfA4vqF/7pYjPKxkRqc0GoVbQcD5fX7Vk0DGZaPXBdSCbCtB4VRoJpG2AG71JB+XdYoSpkCifm1GjqiVsi5b220vOyCCBttqiDXeuQTBYQafhoHkAIt7Fk05hUvdwsPiawbmYCZOh0pcoptjRea0Q3B1mqe6IaicmBoMFtVQgsMGOHAc+k6dSszPJyehQk03mN5RTm602GQhZ/QIbG6VFHthRxBXj34/x9QGDAVAQNuYAGV9hDmKNyqqMXlnYt4jg//oqcqyHfZ4dzaUHQJqcp8TH8iTJYFPUKVRUf7y8nGri95/WE5KD0Tj4YSOn4tSnrIudoPNd52bhILONbLqfhD2WgWPFDUyZ81h2vepJUTZk2k7jmKDB7+rqjghJ8sHvycZyqwvvjYfMB5o7wWN5CV1hHHdYOgvjI0107eCWDc/nKzx1mxs6Rp8cLTch8O3Jf3Oq2JUjAOyoO0BlZzmPbJrBvOooS8M31ZPBBqc8iYIk/qHBzJMZHaEMYZzibPgW5UrU9jKrnZbvOR/3JHKOn37clTGpEDSkf6DN4sF5k33x9KUfqZGTxgjDHwg2HoLjZs2A1HLCS+MotpKs6vZBhx1KODJk8gOp3raij84xdxWtVyhMdkvbJsN1B+gU+5bH4M8C1gkEFEvmJh2By46Lcceluoasr+/fC4gzY3wAXUfH5b8ZxCFV47xb840cbPuuF0zP0mnHXMTtAYPTfLviAkKhmkVWrGIuemZzATa/s2nNMuH8n4bmFY8/vNCGm98i2lYUjqr4B9k4nqOjEEwwsHbVNv9EoDXoYQMvjh0lO/JJtHTDq+94ohIdZJiyw0a0buLVMcmTkyHh0BOsANOrZ7vIl7Iv08AR8dDhgNWtHcpJkEmSpphcLUGBmD4hcSGVGQH1MXMrU7abR295zuOIG7hxbz+8MnJLt0hZZgkbsounZ3eY+vWLUCRkuv6FwzPWfaDPOoZCQ4+1pFnfV5n+pJyl3Fj5T9rpndcuKqx8NWA+F3OsBP5TPSXECpaBSIRL+xXdd61Fw/l0dngK/aQJs0bJFng5PVAleA5jPxrKdqIVdu8FLBRHgm1XGraxznoL/NyvDJc+OY3EulNmZrYBJ1cMrij1OnbrPRMGGQg2q5qh8iXfYHsYvXOHVcu3fhXI116YECBivSt5xDb/cDOXsVzEoveA0LcWWt7Qm4GhOWGUuELkTXV21tJC+0mpbAJ3qcTRkNUgYJ1kdyHexR7nxl4NhldGEOTucqs7NON2W9rjKoxB2ZMYYi26nh/CsHRV8hBDkIvdnMeXWVCbkk3gVWhB2513P9NSxdvTpBVQDpKc9N8sjCefTLyjtPiCPbh42Q7A8JaXWUUIDg1Za9ZzErRdIef44Vrdjpi09IX41nOZd09cFc4eI5kkFUH0sHMYZoImpIhfVvpq8wv3OU7zu4m99wICBv3j/zGG0J80E4fQ1IPhmloP6KzUA6lfmPzdsFr2etx5rjaOAg8US58G9ZCr9qLlXYosAEiAWd2qdAMGwCa/AOCxGoOfU+ksZtKlYDFSUcIYIXwfIYzxZihdj+X3hR/R5kOIeA27/iXBpQRuk9xSwn70jgfNHEcT0EWcGZIeJE2ETKSgJYYw0NT33tKFTt7+TOd8ZcdeeuJngyIGIGdzlx4i9y8lINupymTYFhKgAWnYq4T0L1OeVkqPHAYsQhkF4iHBy+myDQlDpoXRTboLe17Ntp5/I+FTq/RpLWBoWrVtqra5cxK9bC2Z84XgvWUWE84An2iLRLyKdlei4NTPeBJvN32VClhU2NpDpUxo0brnfBFoM+NmniIWgVz7REndwP75SbSyVa7/WJkHTYRGIzpevw+oWBhCMGJGliIeKrwjZsonX2IxKyeSQhqsr3B9vPBcngIXdTbw4hRb0QQQkPV6RL1AW+QHAhoM+8Otlb6CsQ61V/3seEYWLHMaFgLv3fzP0R4eu1AeCAxLHaVHWS2YQaidro98f8zu/Tw34ekRv+dXOKvOpum2JneJax8Ym003nDaZUWrCYNzsnGWgcMCvOcwAKglfSJhhC4nDWMGUbP/n+B2av45UHK8Bcph8KXVuSpg4DkCA2NL0MrLjEhx/YqYhbBD5qx18dt7xZ3WkM0xMLgh6G8EtPTKCCle6PHX5Ag9pZIeWrqF8NsxWQO7mxXvuhDOmgeBtG6nYBTE3WTCoIweH0V64RixIBvr8tINyfZ5108D9aY0X53vbWj+iV49Hf+s7AbXM8YUXphTcubj2DC18HOrfG2N+jdlUodoUk3sC2yiLxeR48MKNyl21j0Zgo5jtuis5UVL37Wwf4YEW8oATZFcWEa8HZL5BXwsmdgHK8e6dac5y8CfdmeBNUw1jO23QXrRq5QgRRAECV1U779LFX/7T3qEOiiFZgpY5fVu2jrEbvjIVhAlXULlqcfHIcIRhNGEzm0WFSsRJKZOF0b1Izw8Ge9Y04iIZmOcfyThRXoMQin/fncijrJQU3PvzAsAiiwxtgp9G/qBkNGV+M2B6WPjMR0Fud8E2aysHIN4oUpPT45UajPzw69iSVwyp2uoaG/7A9Dp8aerJVN0pXQQAlbXcFH0Vea+lubxSzGnVahdnLHrHiYhpyo1LBC7Ha5dkY/u0DMQm22QmFVWouK3i/RA9+EkRaEQMlAtQl5f3/K6IckpG4dViMgbdKEocqL0ZeaY5gj6KUJvAdo9ZN0d6YAqHWb4+WKDJdlM+6sIZEn4YakzrJo+7wSJHQdl38/+g7vbLc63rviy+U5W5lo6ZfWFkJJ5jiCOX2nJzN5shQ7X4tZ/VGkUqgJ7lWVWCA0WdusB7UHVh00iUYDpqN2DhiqPamf6fhWZUuiVBPkSKOKO4TBL5AIcGIgfTf9TGqrfDsI8aLUbVOCJFvMfy0depWBKHxIdMZBNV0rMWZxrAr1MEZ5Kl073IFSxnKAaBalif3ZXPF3oe5HZDDkaji9NKaXQPwrdMaymDsTmEtk4yw3YRaXAq0TtK8yR6KjHwVpuYn+fLwJJiSxwdioIkjFLxqy9MchdL+B4sm1jhFch2q/tPNYxJ7RdoDFD+Rc1gklZR7DI+KgDQz4nINXKHjw69gCSmIIth502amGJId5ZtvpCcXRpJV92vBr2ZTZ255FoCkTfZqEDHYRauf3js4OFBfQLCX5nZhygrI/gVcKIGfpSo4uJlIsBVK3YRJ0Gu/e5S1bqYB7swHLOKN2T/LbkT0Sy0cvlAq8NVwijc0e7XQeBnb2hQZZBvuD62LX+C1c1NyMUrLLaqKYOi4tWyKkzIH68Co8nMfE6fuOHFtEOxnTPk4XrC3nXZFU4d4oOOlAHj4y9/raUW0mEZy/Lmt/abudCAJIESd/ENaq3Id7aLqGSSfKD7V7ah0awWfTtEiBQu95pu6d+yoa6QKczxVZCJQMew3b6TVtIBGOzHgb6qi14V3ufQIk9iSaJUA1cKFiOLvQKbtioVX/8h4icZ6j9djJlc7iRLAr8yAL19Asd3endJe9Qfy8SiNFrh9N2zSIrWI1wtvqqChH/0unyu1qow/Vr9P8ZFn2TxR/KptVaJnY0NAv0Dc/n4xP3PDexmfIVFjIyi4SycERCnKMlf9kiomi43/zS9cgJ9RIg4zOZUFuoZD70j4qLiAG468lp+1q71cCfJquKTrfJWN5w3krNfxbsnZp8QYjSxlzYO5+xmgDbzSno36bGOYG+BNNH/2a8pSUAaF/QXPH9TP/UO1ZJC6qC8/WSUYsTVsYl5fwPBnnB/B4HEXkyR7pIRdBHHrIVuKWKEM/gzrxVJD5OiO9iorrR+NDYf95Gd6n8L6DMHpGbPHeI7LlfRczh7bXZm50kn2sE+hjQe522Q5loSk5U4ayOfjqqexWgnIUNZfhsxIwZL/O6MiNqVMD60Fi3ajiJ9AB5p/FxbcT/SY2Hhe5TK5RG0KXtuC0d2OK+r+1TXh4Nn4pW6bMT9R4YXSSpXR1cGZ+DHQPzOlwK/zgrP9rM0igYe/6W18HGEmLhqweSj5oQKz52THWHkObG8TdTJ9KQPLH4ckf7fh6aGT8bfzGNu8NRhgcnit7JzvF15QsOJnNeXwGlCaCIRwgvYv80HCFwuEtN1DRFTzPBFqyUhVv+VCZJJq4ec7EAZv5H+XTdfA0uDa1+PczYMjuqJRTrZUYBWgW35FXsdgS8/yDQ62OyQU5ootEIXG+KQjm/HAJX7QFiIWH3YUbRA9XUxWfnL6LrV6F6Ua3p+j6KkLTZhydNmifW0XdHXiHWkHfGlva+uaAqI92cw+qMyoTRa2xZvjZ3vxkM4Hi6dJV8COQlhgHsnWh1bWU3rMI8Ti3ynQpnyKGzK94Sn9wpTnMVhbI2qb/In2OFSY4nxTnKxYnHEd5XIU/SM0toYkOyH9nrzhNwhkQAsgw9ozB5aqGXoMUdWPqXil46VvO6BToIUb3jyYpRvJAMvb9GQZIcG/Vi+eFohfmbcFUgHY4ofV1EgUI8yhEuv8XLnoDA2NQp0sddQyzlgTAML3m9LGgfBKhXowVbMH71ML4nZzgnluUqLxjfDB/8w13IxlfgYWED+huda4d12+dRzcAV7mQmLYs/kZsegdA/nAKlruVd0jcl46Px2spjqNRenfy1S1DEECFGBWMZX7PsH2sfDIBfH+DEW8HCeaQyrcnDnLhn76thH0zB2J5TgCJ6bMHPxlhXqXTNheaeiF9ROFCeOU7P2TsIB9OGIcQ/VN1VHVEfTYg8VUEcRZeviVDcqY9T6806Wjtg1gvjz7rhhQW4ORqLyuxWHnUm0VFDMRqyIVOu1H5U/kbeMJPvSJyy0NqI6VtOydZoBs7aivIsriZ4DcusHDveezBLNGyFz5F+C5Mt+CeOwrwbPpYvinv0dQnuXYJgaeS7vll/tJVuSrJZilhQ3FPzOsff8v/0T0gAXZRgjoCTKHs/5wXaTzZUW5GG0ZLqvottMJBmp3jJx4tT8Utiy8N43NLGgSD0JBKkxbnBI6Uf67J1v9oOmaqVKzmGVEArMxfNqIHftiOoWAC+FzPS0bg0475OVKyxCP3VVED1YpeRvV07u0+MKwYdokjOExD9hj6Vs0p2Q1cq1c3uRBw7sCqORtiPwhrm8ca/yIkNY24Yi2Ge50+IWsVAPutCk7QGmhHe8e9BADZzo5an0hEkr6g33jbfDS13sId5pdqgQMzE5Sj7dNUNEJM4goBz+EcVJ0YXuxEzJ2t+Mbo78ItD8bOCeL3fy941O1ei9NuK1mVB3fJyiyMHTBlqxW+B3Vm+ztjG0NBZOsDvl9Iztesg/qVGd6Z+8VJg1ClSWISxMhti4aPUSOv6WeO7uKErowx8k033tSNEKa7xP+UDAcOrydGmL74cM7ZZOrpCRk9osD6JaOa70qeYaHYUGblVfqM42u9xHzSYER/j9BIHNaesJtYY1hfGk33FXez1sv7sddEC1TC4mLcwL8qBuM0ywwxfFvI0Vm8qY441qb/8sxHJQGjqUWVxlh2/jclxekOrj89+X0mQ4n5L+JpPGPJN1EHm0GyZJ9N1NdC/Xno8Z9CgryUu0EzEsj/REZLDtE1MleJedYMFEqo4ZWF8qe7D2E38LfoSrr5pVGm0sY83ZJHgHJEKm63dhmutC+d0NgQ0KVyDlWTBCo74dXCik4gxgXAegJxmWYDIMCVxRIRBqnyg9ZGaKK5p08q2oZ6NC7IjDj/XnFjsVUpOemjxf5DbAWRPqwLpXASto9RCR8mIO3aavfcDAAWtA+0f4moAiFdtIuN/u9FAtwf8UUqvkh2tCyvtvD11o7NktlJmSgwR6VIbgU6rl3dAHZL3Bce4D4vsnsrlmJbL9zFUyZ+btiWw/8rGGwBcYczokAaRTkzV5DNGEgRC+bsilyiQqFVdj15tCRBP7LHETHJXBYRrmNve63Q+aDdZHc/E7zYY+NBsPOSvc/79SStxo9qmTq4fm9A8wlR/3UX4YJ/nTNAnluohaxpl0TQZWfgbYJqf9D590i6x5jKM9aTBKTy0ctuTBVF+cx4Kbkk+L4rXqSqLF1ts00o0qD1/Xc2t4oZpxufwoDmi13nFY/2DhbsrOZwg/JQVshIn1pD2XPAYpjrOcgNyDJ8rKY5BjgRfTc6/C0HchEZD2RTOfsI0CF2GNWdCGfGUNHkE/ywct/hY/L5HSmOzm/p5kPjrWj+ldWrO2OExN/3dceO64SzfH01YT+C0TwZ1bU3omWV6mwNoXEaYpMb5VjhQPmCccpYDqU6vGzo2PfmlhWCqQ1/gZyOBdsOgvm5I1kjTW1YXmwh8HcW0HA+WeoNLFDcy5VLOx68TSib5fFdL80c4etzojhDZe53Z6b0Gpv8gCWrgJmrAmwDnAaM6EJpMFP9TNT2Rmphargkjem1eGx/TAum54lR7R1sTHErVBXuGkMcAQDffcFgELTEAdjDd53HDNJm7DZSZNEvqM1ZFAHkwPlHLvAa+y7qccBG712+aAeaDs0bVjPa7kzdkqCR3irJDRfhX4rvN5X52ynCK/Mfp+U//5tXzCeEhy/THQ3hwUs49Ob4gHZ4/ewFb0TRPdEFtdd4bftghHaert83DVpPLkWbGPOVY36cEwFqZ5AtLjZ5RSkH+pCZHr5+7W1aLqv0qOiCpcNvm+AdD6RTA0KXcx+/nALKx90UUKpCq3m+v5NrW5esAQ77XbbzZwSU/Yx60mDz+qEub1XysxXmLjuEJJHa2WdLD+0TrQArkn0XpEYOlH8vXvqD4JXtIK7sHHmCQmCfa6249A68l2lz/X6oJ+NdOxVqJ52w3lh1xeq7rRNzjYzcdbkFp3GRwfy9K9Ccg0G29E5TRs6IflgNVnPyooMK6n/H/hFxaQFtU0eVOBkVZvDgi52TWmC9Y/07rhamDubL49C5g6h4b2TcbeLgr27Q/OWEVQY/tKxdRtds/jT5/6Tl9JG+EOoD5SC7WUIJD2Z8b+BuMMCZre1Zj6YznO+UK2s5PGyIGdTrULbgHGlh69hFIlfbwWA8Fx+O6lUcalYlSvAy2IV3Zey+P6Qb7gY625VlZhdDMDuwQ/HzuaZLUewDA3KAq1q0NPYQRMWfXQlcG++v1hBpVfBZl1mAU0UVj5LEzO3cHld4xyxh91d+joQHC5u1wRv2bmj+LQCaGJw8pcYX3KGRmkzR3n8HlGvfXXM7ftnJOI8R5b0J9ZnD6M94Gyxly5zmXKGlMRLe9cBGYWGLrwMQ3gvQ+qKNlcG+vpia0ilhm08RhdQZAYmQD2Bb5xbbp0PsR7AwBway63ZrlYhmeY4IJ6Tg7SGbtLVXlUD62BsIWr49EG7gHuYFZa3lOd8bpmZ/1iTvlRuDqW/dPuoHYj7NIo4SKNHPnvN4DEKUVRHwFT2KKO6Eyn2tyyqdlO5rMYuowQ2ZZqTmaTYkw5qp5oLoFcJHovMEtGcbKXVJOi5ZY3NmiG4rUcgcXL+8tpipVZDbv5tdpKcI0bwak5JB5N5KXuA9vsz92EWPYAJsA4GsXM/tvUR4euBLRkaQB2NH7DSUdsF761qiE7C5h7MA2Y6GJUBuG5AVqSazq54FquRSwkJ01evHq9wi90+wgj1tY1HAvlR/cg1wmPLxUd22x1EUsto0l7xPMVcmKVcb1Ff8NShw17pqaWDMlYYXU0eJ8b0TVauyoFmgvjoT0dYjb/Avk4GN3dVzfb0+ky/n2E4kvEdQ2WCLvalQD5kTs+gzJoMbUNcw2PpZAKEoN4VmrMHcceyfCcEZipmg1bYVYfJS23SSbSs8Y7HvJmtYGLjNd/ebMgB1aasDqymYKI2JBass0I/2KWn8tZJv60gIYKIEg8I4AhWbJVZIhKNq1w2MvAo72AY4jyfY1BUZ761gVIjJs2X5WV0nPdqB8hykDycMMxTlxWfFHoSl2PJZNOiqh7zxbHEvdYt4LWS19i6rHZXttxqHSIFvYO181/0wuYUMY8Dr5Csp5qlWXlfpi8L3M0PDR4b6bBVM/F/dYIfYaqIzxPpXZ3IUfYMqf9Ked9ntYRsGjddq4PLqAU+2U1V3GN5Da4+oQBqbqI5VAQDtpRlPc1DMmLHPubjDTREbQiF8+RNtJBzLwDXUGCATcSZy8VWzu8rpjaWkvyjfNr9o5HPeNV1ZS1bHYUVTBXtxMzqSEty+1uG5RXGB25FaIKFX7qrr03O1X7RWGeV6+nhPtj7ch1nfmnGdaRiSptMoQwvNcNlBqqzYeeAsWwGuIfitn2xo+QkIAN04JElYhGwR2CCwy2H11yFLFDwee/6Qyxu9PPW/gONrskSAFoOelz0hiOvstLGlEqiJFxypp5ldGRuzSZk6tJGe0dLxOwCr9+SFKR7GR/XfnbFtqKtaFKjd9wMpbVn36zIx3g0bhi4BWFDYT6qXcerEgkHMmVqBT8pEFTTi/9hESxbVrPI9mVHQeuJDYcV6teqDaMBEZUypdUVjpf8jCsrTF83Po7hMJ6LUscBdB6iMNYVPwO8fKNnR4rJ9XJdiyfjP5iGq/Beixtmdo9qQXcYtR50GX7SeYKKXeQDT/L12TnNNVIv+7GqEtBeLl9/0NF1t7Z374JiS6GOh+qIJs69Q3o3nQplmCsvgXLACrwZy6IYn1RxqhF5p1ZH96b4cjCY3y2x/r/ATxEu5CMvFDWJeXaqrP+gPHYmbz6XHWtR9TNbdo3HHJ2+lrG1LuPwqlL52CH52DZ7K+84wcTHoKt8IP6Rw73+g5qKtODiFcWVnm8Iqc3ZYpqAYYy6FN+4lHas5d3twZgrhEaZy7wp6JBRhT/MGolAEgzlKNbq/2IcpRx9Sd1wOgBhQulvxtjuqOIezVEVfZqm8gyxao5gaVF05BGsH5UmW2yU2TR5gZpAjEp6ufuPTHJt4pNibFWbWIa8TIkWrU+mb9Wj5b0TENfc29RiwpfmrbCh78oNdFtUxS/St/L0yU+BAtgHd5fdvZTFHjdwuUY9fiH5hoftdeF5rJYRqUifedsJ9GuiWtBp+mH+7CAANuWIo4FQx+N6Z5wITYP2BBRoNj7eZJEoUgqy4FKEprRLWWtvguA9A0JwhcuogSmq4r7IYMtk3vz4nJnst+dC+hCmvV/0UMr4RGMw6yTeCIsHMc9hve13xJublqGYRSe6TnySG7mxyQ06CjVI2z5xxlwZLGBBHblMLqPMZ2ltPjkFjW/BwGNbGAXpyPvNHQOx/nul03ivqRisHzncrgu2vd/w/GJvebC33s9Z/hLuKCvBxfYtUxq589c5uNOeHDH9bvoAybK0DlqMYKCP7oyiScoUpVoJHk+QtXXN3bIC3xtAx2EGjg49v36880zN/w9AdsIlInOXrNP9ob2Cf5JdRBThXFzK0Xxqsto+TLGmzVQhDQRDHV0GslnQyR6GWHYLwr+Zl3urcxdEmJZuLi7j1olyb7lajzUKspxkkXnA4rPqGkrJ6ZDAKNowO3ySz33N+WW3HxH0Pl0KQBWUz/Z0JAfmYGMYSbjyx3IrDF5ueQoWkTWYOwETM0CnxlJsqmmwhM51p0bmAKmox118ALt5Jrzj0kTBW3p5lJbD8ZxyzY6cQaNRok45qwUSprvhx5a2DjpOFkWxnChhpdcFiCcq9ZXKcXXERnGViUOXQPMPs570v4nxdY1cxT1rMfCTicPcyKtds2vFWFtLxQF9krb6WOovzrNcDSnNGSQKWEQxUIBQNDGjTrtaElYV7lL+WJKQrbpKjXVl4y1sBmgKFITlk6ZvQbwX+h0xa+xycSKg+bJe3qZOgWKEwoNHhvQ3KjBW4XRr+OBOqEQDJwRil3gIfrwnParWdgw2Ky+q3veFeiJBws/N5dQ/Dzzp54G7vcRlBdtBHVchCVV/g1SBzfnnYqru+rmSB/mmeHzeH/CdkWgMc4SlzBqBUUetxtzJdTl2sXzfpvEHa/WUCvuS4vaYcYe5edp6hAIMzAgCj1V7znhvxMXAuOvRQZuc29R87TOBF+fauKHcpDy3iFymN2VO64zAFDOpuYzNBvMk6L+XKdzgvRfYhKr3MgMW5UbXRV0al8t2jjAJTqL9/fd2o1qLJWljQq1WVfp75IfbINOYQq9MQt0hDai9vz31030h0A/nE8rxcOdd83URsN2Q8Jzco32fv1+bykscek1gCpabMcKPVkCrDMzWkkVehN1GXA2EQQTmv7jDwHVaNeY8DwUz1rIqfnHAnkBiQwmXLu7jRhFe5r+zf8CIhfhRhm8ztw/uAV/4Nv45fa3LCYkrAhyaV9AheTXyNTBFEELUhCwSqKdCo1VUcGHOPNK2lB7HrfMgQuYfaEYL5wHusHqfq4+HOleXyfyL7EEdCCbDkMS9nP/EefyojqosMu96hG4C1cAv9p7mqBqg0Jpr+2wrWWiMK1nqAGXURRiZWq77EQD14a8SPPPnzu7sOw5EDP+v5K7AStWDjtx+SAPQQ8eeGgu6o4KF0YPrlvi/n35zDvO8FO9Ug3QsptBeqtkksYvkuc+ZjxZ0/1bumR25dq9ZBdZr/HqAEeMfP554J/Sr/CMI5ggroj1GypoQdXbbgibdTQ7SViWkuevb6BRBm3uO42wTNaRtWQu4ab4ltJycC4w3RvXZ9XXTzVB0+xYNk701r+XtZizgTfnmxqETncb/TBMf9KVo0Do7TxIWiSIXNg6Gvv0GrukIMwXnPWSqU3lXAO17z/tQM+5Ljpf4Cz2lyMnF6X5N6z3J958kCqpcgEjLjmQwqRZiMi/1NQv5JaUnAZmEhYWiCSWPspwtusE/ztI4SVVcTU58Syanqs79Al1epiAfcYUtaWmjEFs26BEi72UJctNpKbSCSRt1rZEEZt6IYqPisz3A9dVzMMt6umNvKFmxk8kYoE4SwLKvtOhwbJ3UXX+zGDiHwOqxG5YzUvv0EHQABWcjnYtrKtVumyjGL2j2twVbIJKV03sW2Hi4SlMnCTXd/TkSYTqZI+sEnD+hkG55EtEVTSo6CogsC2qWXLIeOm7BfphvPHcKgHsAqGmyacuPykxyyLsWQbOkbm5AcfwayGPb8/VMxV7heEgVEHwAfF7NqLb+y8Bqtauesp5Ri5YoiiIdT8bMLXrkctyv4rm26xcyKOnbFQWfWZ6zMv8DvafJMRBrW4HYQAC2zC2i2KzkvIXZCKnnxhskKOpAFPUa5wIIwM7XMBwDXSizWdCJvHMPDIVkDr8xEf+7ULOMEyywpCKJEYzErsFw1Mj6uHLuNTcNDFSBq4/GthDXnv+cCx9A8ragIi4iixQhUTug8S86QrvXdCwTUaQvigiyI5jxfrRAe4NYw55isjSzBVqEC0GM2xZ0cv7BvCGOYGvu30LObu1SCYCRUR0kkdNFC+XVwgSA6sLR74BUmZJLKucLw8fETDClnavP5tFBvmxj00cyu6ycZart4+JucbIIN2UicceiwBSlT9Tfr6sE5l9v0izlv7HY8yGXh6UPsu7sACD/17eZJ7oMExlWcef/yysbibDoSY9e0o+nieqwzT0BFry7R4RQVjQaLYoCA61FXCxRa8BnnxspSz+0hwNHEbtXgA2Fx0w4m1XMbdfq3EEjANCLbgYznTy5RNNSmdYEU3QO6O1AG6/b8IbQQ7DObE7wmPq/6WABBwa3k3EPHOX2Tn8IocIpamI9lVWykbMfsk8C6ZIe2VB2E7oq2AOKv+pflK9br7zxnCCMfgQ9rA8C5PnQZ3cnycIR3bJucgABmxWjnGjH9XmDuPj5tU1r7NSzTxeFzGW342WssPaabvuBBSjyrjgpASZv6TOTXdSJgRxdshcVyVj1SYP0LdPr7Gra/UY41jDVe4xJcd1hW7P/X7J/5xgzusImnSbE0YonfQ63MUoWiYQTBkqVKZeBiPPovbaVKPgh9wVtuQmPifmTalRnz/RtWSmr2gRGifZ2pSZz6iYE48HAt+3Zc2d2aY0oZUPgQh0aslpBTUL69L0qJATpKQIQ9VNW/ht8r/x/HTjNC5GWG7lgIjx3dF6czUZH9Kfd+v8NWQEMFihHaMR9HWX8YBDmRfuchxflswy4TDf+Mc4hak6ytHLPMJYN4q3Xb4EzjqHnh3hDfRPtcbBE7Rt4VHSRFBF0buOZRrG6sc8XSi6HxldrRq6tD/MCIvOKCU1T5CAA6Vv5LjQX2dLpnZuS8Rv0sfBtCjbhRjR4NvYafcyYHqMxcNtx4uXbtaAN55pJveivNRzCVxpvH7aU1crHqluNei5MCKwL4/3hZwxar88s6axkDBnaJhfDcDFbkkC3ibqEFYxgqdvaRhhrnRq0aK501TntWY+ktczvMLZGw8uTOSlLgxgWp5dZ/m5RHg/Tc+iGoFA2+SfWMaGVSiuay4pf4KYm+JhP65MKNPEtS0Od2toqbmCsyh2FbWCxEN2peDgGfbvB4TMCtpzO7h9Qgwg7jLcaxKFqDDlH+y3whmb1rFv8kKl2+1+xmYqwf3mysW5lsY/HzbGg9Q+lTTs7JCttyPoVYmun2cfSuYOjMUCgPE5SPjQCrt1dOudSgplrmnGWAXeMWNf+VNQ0F/NsXphpNGmigUZozfNmN/QJDJ6ognnqZpSe49QkyteW8qQrmB0XHheD/JRm09Ds7BJ9jgg9RxGFbdwb9Q93X5VPDg8bUA2VJWiJoDzhTCpi0gz4h+VM+qMPADrXcUwv7qy3M0RggHl839n0VPwfLMGLSU4amrt6tolZ/t/QH+xfq3mNxkZhJG8DcmcwuzNBy5GlwTcz4yLk3jXoJLMwiirN3gqHH6d1ND/14xIats8ufUpnhylDBI+7z1ujMZfXhZdY2LJLOGoDEAauq/Sq+IfHmIPXnJSOeBgI6bdjw0GXLrraKID7gstaOJWEcYzFB2ax+dsSw02G6447Mu234Nvl6bi9ibb1F6pCqSbV3yItwL6bs16ykhzU8zSDSbLsZK/DKwsQCLrbS3EvZ9WOyXWNzk96eJVlvasaeeMI+URSsP2mowugxqU6c7BH1rnnKfowrD72yWTC8IDT+3YKpVVAF60OGcT0O88xVTU2tszRIx4a6y0MsXfKv3JtJFbDc/jtwtqAX7X6zlRK6cHPLrRtXrTJHNEAdoSzf2Ki372gcm5djtkgTsgZpHi2TscYmsguTActzqzsrcIFOVq5GXX39e4vcNpJFfezEJjOscFksNY9bwd+HF3d7bPZ/X/0+ct06hU6bt29YcLMTB+d0RLu46O2Hxw+WvxF45di1wJoLGWdKQ846U6ROX8YQKTSwVeKnhUDEotyz1Os9VuHVqJ82mwpQSUoI9U/Kmqz+O3NVP5PWQsgdOcDENFlq0zVcs0ywsadGuP8f3yRwQekH8kOMURy376TD4qiStJ3ODSkRBhj+Ys1GHxpdxiGO7nICJOKYTdVn+nswc8AcPb1UIwPF29vThqFdK8UbJi2DbXecG9TdGtwp25dgwUs85l0Mu2UVAVjQ80N3w/hhD/cLxufF5CEiWD9cVWcBnziGpTMHAowXV/maXOoPwJpYDRktWlaN6bcBL30GH3g9oQXR9Ek0sSOp8WpPy9eZpc65aL7/QWZ5DFD+q0b9GGe9qT1IkwL0vuwos2E3/AZ8dEW5HHjlkHFiRe0ZrSliP/+E9F6hO6vCKKL4PJzBqvnBHcsnm88y72U/dZmWd9O/jJdKHHqkQbpbFv9Qz19GBxPxtWJsoQ39NXac2UfOpkvlI16+KTDoL6lKjBBTkPS003pLk4L0cc6zw5ZY8hsy41etQ7P9MQ04Kad7hv/O1QHHETME0UBLxbt1cxychiKpMbG6IH7EJNYg29Ugd5X3iNu6tbmXbqyln3CEoC9n7Z4ufm2YPVB1Xk+GbHcgBsdNpbQK28gk36QOwRC6Rmv0HJBxlgzvl0sosS43x5A/tLiX3t4A8wDN0hE9bPOzuMpHbEc5cbEbE+TwvZ0jm8KUibOa4XzabG2vHc3/4SZPailftv+5pVVA8h9eji07YKzcO+hObViBNNnA0JE1ye1B7mUJXvQgAsneBi8Cl3VQU5XwlOatF5AKTWPgYaxqr8AW27SYczJD4/uoNiO3iP4AMrX7Daso8rDNDcu1atpZ7fcFIUOKC0SwcZ29smvHvr70c+Gpzt3tI0i+LaHjnt5efh+9aYMKyuywAmS/l/qSd6xI1uJQgil+tR5EJogbXxTD9G8Y+Ok7emCH/PiJcZ2+8awNva/zLUnmxUar4FRFpgcGD7aPZgWJCdAbYJa8bM+SGU93T8esyiw1qzjN+arYtGdILareVcGYILHC29AMpHo9f39rtxdmPdAaiOxdJOOnvavY0k0eRc49jofCKnb449qNxFWzml09lvxJIcoTeLP3NHkrlx2W2DBWc2PDXpbBHcAJgEqDu710bQnwtQglMvjLpvzON5yan1fvu6Mu4R/rV/SfH+J3UJL1xdF8hyogP95/e/rBFtenPbmlOE5QCuE35g8WqEsQvbWc9UZ6KHEFq5zpL7Tav0dNfwTyKmBxYNjzGmW79NNWH4hGEeaUVA1Ln1xHNPoMoxbmFdbBfeMP3DRdzij7AcT65bgmKLnmQpSuNKiz0X8KTI0prxiWEVTyppZyVLAn31OQhHUjvJ9ptUkkVUFHW966hvdY+srKXkNPk6CoBsI2pyYZP91qulBd9HdfpNe0eKsSPsXta+5xDGqmAPvHAIlo15QYNTX4/IiWPU4o1BDlHsKs7ozmItO8ICxQB1G0UM2IO+gLetnQKu2qkm56RUC9+kCPCdUmxQ6qt+EZvuVykGJlSVBPtlSckI//J99W8pwXD8MBv4pwWFfpPD7JDyulA+esO97sY589iwTvdLDoAVeKOq+b4hmkrXRNiMTKpsG4Zfn6wbadbtf50h0/9RIYayrOLo8KbaPPZ2xu5r52sIH7sZ8coqg1O9lIkAL4VSWMYOVw4GJA7wR6By2q5Zi1vD8cxdFnd0B0YAwGk0oHX5L3ybMdFV+xkUeKftR6n0D3A6EacFjm9mIGMNU0uoWz9jduZoXu3LNw3GMEtNl3Zt13PS9KBy4i5oYMKKb63w/OUyHTkIL70KzU5tepXc4oekIqmOehKBP7hnrskDy6WcXCZU5nt6mLZD2ZiOGOHgiwcF6LlstOCY8cuvZC3AO+aP3TIyTmYwZsS8Cown47aeat8AgXZLKPakRj0eG9EHK7m4L9ysETn7MzA2+8d5iAl8QskkHo6fMGoPOJxKDLLqBvFO2nuGjGR6KU2qFA+/U29J2XzvIylNE+cVg629poimVJ7MUiqUYvYYYrj5PopeQZoDOh7CHr7/rYZdrIwmjfIgTWv//MCchmSWPMGKK8k7JYSZ58ylizTulWevkxipb8hUSJv2MjcilYF1/LLPV4gpen8XTcUvH2C5woE/zpTIH+9PLmjbQdISlYKiXmTV1x2Y1eYnwuheErTKuhvMzEEvOLxOxW6m1fPZ9Wfi7Kh1DwSgv9Lfjhr3S097OSOAWielyIlEIu6T7cXjnBDEEbwdOD5ebgDzMaCGGHq1FcCv9o1LPeRK3hqB/tqUebLSV5LMQKuVWj7jSR7yiCVFobTdyPWhLyVfR0HN4wX1GWYzYPDh2bs54Oq19+TgClq0PcVr+c2YKTY3DaCCMCGRjlIvX5y6MBt5XssTBB0f0w52IyC2PvtP5t/18IV4dfzKfFh+b404zHKp4GX56zINwk1Jy2cHvMmVKZY99ugp4itKmSpDFv7aJI85qxnVwqOP2NDFmi+4xfEwbFepdsEmfriiZ5eT3aZDidK2TFT6/Q6v1ICjUE4J2nijzamyn8viXF2hy/Qf+UkMFh50SqbM2JT66FNvqi6Ts6PEXz2qxSpNcACY2+01Cm3JETsmHA21RpjO1qV8FC2BxlENnZ21+opEwFqfk2G9NMN6zy6SKgOxlNoRvX4H6DaGznsHVE4TiDLQWmQ9JjClSjRyRS7cjDSOvCH1AkEaBlVLvHoQDFdAx6ehzJtyPRnMSlbkzW+YnnXbL7XT3lR3ohGHOa6kLg4PpGozfAZTcfg7iFHmxG8W/tSA5CheMGth5cHiHlSfaDKZPY2LODmWEd5dgY/QdJ2osbMhqMjMxiuQGk6njaH8yzCehIOmRCBBwOnQDM+j3fWK55MM8mWb6YgtgjZSvdWsTohA8Q9WsqjjVsXg0vohTkOhTk2BcuwNrioqS1Qmw4+WqF4gKKi71zNkJwiW0pXYFyeXwmQ4SLuPJm8P4qpixzl83C8YIPEwL9cY73tFHiIZ27t5zbQrtGlTi5mAW8Q5FYl9ZK+PScD4O+2i5DDcX9aAlNyrSKFjE44OZXzb1JO9dR9ERilNcJIxku5ESkqBriXmtbBRNK3g9V5g4nGxeHktvgXtE4PoI7b4ESxslfb4IVCv9q2u4IpHF+vnFTTr0gKC3HXMGC1b5+AHqpSOXawMzuvQ8GD4d8RbrZatp+X9uhVU5ZIq3PWI7Y+rM/M9WpPHJOpXz4d6pj6asnzpPM6/zTBfxJNB/1FLdXDsYmYvQGf4jFPmjvphArVYMw09oZsN96CdOvT48B9RZqX+yeRtsLs45+eFKPAb0txddmijRCPwkrfC/hCPS3HaJFeyY3IhKpDuPV6K4iDfjDb1re9a33Bx/t7DLFnFXGzDlAh/xQNKCKfROinU1A5j/Iz6kV3F0AdmxO3JX/Pe7/DL6n5Y0BTdXF/9jtO7+Kh9Ew7sW8KkLGUjo07kniVdH/TsSGJTHHN3e+3+J5qPaY8/Y6NmkwBtkYsXB1AgdFwwPT94ivxpYvOPaS3bGevHxiTGYYpXE5Q96wx2p/2WJqYTuVl6xhyEHB5YRuATHVaPt+Y8O87K6Emxk7pdOiatKYB/CpTPglL2X3Sgs+1lgwqoKwUEx17NeBwQdk3ZYBGaH72yDUudgpsREWGpWt8j+mihT3V3k6S9NomxRcWgF3IA4hqqon/QadDlioF+qersUa52r7QkuLKVt+w6KeDWNLaP3twRYJn3ZFFFAGFtiN1OURiuwXOGML4nov2SCPYJog84f6vrPOlaAESbSflO9ONAkqbKxyrsA16tW8/xWQxuo53B1fsNuhruM9wWlP4DDL0Ezoh6dd3I3VhI0ZDZ6zbEDOEQoFUE08h0FP2Kiiz3zNULgtvNa1keqhtkbADnQlbZyTUYbRX7/AB8l1awNZ4GquS9RSiw/OG0g1z6+kiNb7TXrxBYBt3Dt5Ex/d9sB+T+tMgp92ApHOe7uUt57sI4Yl4waojcprcfudFFXvJs4JCodfQD2OXhz/CC8vGhcFV9jlAY5CgoNCY40JjFXsvpFO3XPUN+fknDm8peSd6rkMDt+HpfTeYh60tfWDzxLtIK3S6TNjIrVv4vFr4ZX/D9o2AcweGwcbaXgQDIMsm0CFeXWG0sIvZuduU+PL2Tr6Njp/eKEQmSfZKLD4Y+jGlgk7rPUq+bfWX1ZKgj+dvaNSdx13SiH+82A2cX6S/b1JzYXE9ND62E1Lgo0YH2GA0Q8XH/Tpe8k4vRXWwpyQKNwHtZA9SlZF3BP3VQx9Vdm6/o7a0oQQd0iMWadH9vsmoUgkji3UYtTg0gXx/DoaZ9rWF58mAlKH+ZSezBEoe0zLIDjkGWVpP53Lpdd17GNL75IFB06W32uIRrB8DUyQd4OYpIFJaWCnajJ5dgGLFlfbJJQZixuiLaYu/1uOwy5VNTV23ema/nE8WQR9vyzKB9j50wErDfYm4DBn8AE8QMmiywPC41ievFp8iQ+GcXY+jMrOexhM8DsUB3/cSKMNrmFURWXDB9n15kEggCga+OVksvVg/RYH/EwSA4qYX3h2w1I9iZ9JP8iwVoXKrzpnn0vxZJmJUP5xrVn4XCqYE0XU+CYwpUIARQv2R8CNryttoAeWiFz0BA0lzzTmmoY6fO8obX3r1iBz/5kQ5PctKZkRWy5S3i39lSr8k7EBhlbsabyAB1fKj/Hueb63lJRcJisK1UO/662fvitMNtSOuT/eOdkfted52zz1zRGG9jaFUULipI/XLX/HoRDw714jQC02dTyveorj0BCtpTLJvhbBOjOjizsRiPvTFyepbX87yayjymOyMcLCG1haL5vlMngcMe366oeYhqrk+wr+hwB+xMFp7vnIpyo6ggS/AnWGCNMN254cRcz40nix91wOgXrIqarOcAoEU2oBuFu0y/vYuWAKDXTa6QaEvUqHSnumI55feZqU0E2CaIaB0NFjx+Q8tp61qQ1rQIe9XeDJEfSiPIOKLnIj7JrUuJxTolLnw+3KZnF7p7ko7E7wi3DGIXTGwjhpN2bqtRhnSZPOSzQFbEmdsRxrNqlisK1BPy3QA4ZgN4k/zzMHkEfdio6EpyIuMpUrox38UC4j+yVN8XAbijeoZDSHZaH5YdIjK60m0OOFqopG/NGXUms43CGyOVXN5PiCRYWuXGEuTt1zz3J464PKn/hgOEMlw9/wG3V/TOu30RmkBKFnR+PClQoiG51DOBNYArLP5blgYaLNx5pHQwJslHbck2WMmdq41HeO/5Z7fN7L1TRB8KrcDxQm3hyPcDD7IRGCg37PA5c3VyJqfX5ZmoC4pwYIl4sxJeC7dp8EbF0iYxkb7LDnkioUPu5mqrjEuptvoYx6VnY365Y2YxTFe1UfDF3gRPc3pRKoQ9aOwHaVBquZ+2NFpjzWzXPEOFhCt5sVw6bViekpdTQn2rpxByhpnbkQunfW46Es18+vtcTjqhHDNzJeW/9HPrzgTaAR+Q2xntM1brAnylBc5ozEVNRGGg5G5wmFHimZbtt/EnH8+uMbmMY6hnbacsEoEJ/RvMaG0UDHgn1faVPrdqZw3Rpv6Uoup9yL+P7Zts4m8IYuJ4PvWpDlCRiqaEawngjug1ugN1hrX0mYvILuTD5MSv9zTrmHgUX5sHzAaWFCa34HbZ/TpTwr7ENsr/fCL4TlBi8clelfLBkShi2K4Og0T2dy0KMUnzTIza7iwmz1xdT9i36Zs54oNS444Y257mdv9IsUePoNq/oCtqz9y05sedkKO4lNSO3eEqfeh6N7H8v6fDKJ2H9CGaV3I/8zwQfV6uUG0C4pBZH2NwF6WjpUmj0Ec9Z4Ya9dJ8hvpGwzhp8sM5SpweODnIaGoJyesSJeSzaKZHEKP6VnIu5DbqBzr2DwdyciIRNxEppjdPj4GzcdscRmcssthuTzqpDB9XpkVMapXzXytABhI1YKVK4cTxrre3Qa/9fpy3TjeqYplTCD+J7jY60+UzIyXu74FeJfqiIxlCgJGOdQ4NVPjNkrpcCH3o8jdIa6a9dS0ioWhZxDqtfl2WrmGahyQyX6tKx6U1ma47wkWX7GwCZ2pk1jWDBmVsQnhK6izKHNHT/pHI52nTT26stkH8ZRaROhJ9aQ9czbQaTpNa3OUoQH5oBMTZNAYqvsLQHPBcl70ZNeoKX0NbZz16zgz3R1S7ASNfFQKzo16RNrhPu0r7RoZ8Nd5fDSXwUgGPVt4Wax24k425vAmFSKUj/XWZsjHc/bLJctAJXNpJfX0YeaolFqdDqQc9+32K3qg06tx0DSuhvs5w5z/TyBgMmhLaAIIDoz+3N0XtQPA3Qg+JDvjpwEfHrIqg3SZdMwYxomv45LandCuSeaQ2tzr7OmPPfsDcDuxiunGj6JLTzDgCCMXYx6R78a32purXfy2KdTYVsxZk5oLpzypgnIab9GktRgmZJEaw56PNCSycV7x0Z3MgzEVUmsVVU0XsEiQw6uowImcW6JVa+BsG7A2yEH2Nrd46CZ6t3LOjdSrfORZpQEOjWx+UREzSrqhqYqdhRjQnRurX7F3+zH/MF9lhncJot2u6dLNliBbrXw5BoYe7Fe3IxYraIh2iOJd3Yq7uZDhIj7QltNL7gH2OmWoKbcl57v76rzU3ZGgyDUPs9nr5uh68pAJ6fVEuQfyUDit6fvyvHSAjUK856QXjvzzyJgp9V52CHhxYvLqN+awfdMz4raMee+3lw09sGMnUZV+kncPrtRID1y/V/wtVgFldCl3+dditGV9ewnsCa2aV6VjCFGY29bd9wj5toK4QeW+bTLjZrv5EPzqCUVfTqWeUxnU+ukWh287kRQgsvUF7ONbFfXCmZxB7DODhRkrguDpo1oMyGUiLObZ9hm7Ow14DTaYzNPhf7BA/Y7G9sGm4mabjiBK/3rdvtEwNE+fYUUCGirn5QngGMSUPww1IRA1hG1r26xf2ozu1dW6eAgJ6NgsS65GcZuQtfOQ0jKxoHq+vxqSujc56NnmzbDvonxA4782Ga5CgcPnO2AdTP12bOH5rwPDa4Y4Rxk/5cw7/cDOsSptuJcXGT5ByaZKyRVQS3qi1xEVAdCaDQvfbvz5RH8tOboAej4f9LCLeSiJFkwXhk6IUjMr+Ckia6rCRSfgdAuUJU38/yY2+qw9JNHujYzycOjrDbFXSt1qq7dAqy9d3CgxNfbfFUmEDz2jOPFp34252PyihKM3eMkC1jBEhpVkquHL9xklXxhhkuUVg54pyIVo2OcwLt6N4YQbt9ncC5AzIF2SpYfyN/Ghio4R/h5zrRboqV7vGtZbVclC0oEK+dEUhfkn2zuKkn7OthB8ds3sn8VcOhiHQbvN+2ZN1MsR7vkFgerwnv0V5OoIO8J2Qb+iK2rwqDSGA2ay3XagGlf3EiExzwOQf2MYOKuvd+YUtuZc+orvBnE/eA5kFwSenMK7lGnygHcKuNt8AkRyexRFtVzqm2X2kBs2jOfqQIC6zV3RgbomOQ3YPimKDoYoHmiawOw0OxYHpSeao9hKiWdZWdlwT05O0kHmVg84JVj8xH+dWuzjWbLi9PmdSO0vVOoQYJQg7/Qs5NJ7R3rIrnN+d6XhD3zg3VH1aPhk/HC+vdOTrkib7AVUdSBvM790cnAmtPnq17fs+RgcRSB+RHbYvZinAcTUZCEdoyC9S3tTnD37lD1Gz/E107jnpiJ04XeIbipG3YFvPih0lbLQaNFVxoMaYUlD4sCkNxKL/96XyPBQlRLzAU+OF0Xq53QIUFmlcGaMMA6mGpkehf9aMbAEcF6qTc7Bz6IFOuaw6lTtmA4cWgYRdh9DSg0Woid1gpsAMcdAoitz1dYw4ZlP2gNggQBGHgfLMvTYZApm6i+Mlg3/mZOjdszPhT19YVNGi87rl7Ecyg/hn4MqGU04K0eNOLPommYypMw0jgZB8ke7ETnFQLHFCszAQkvKVYIs6EF+CUxRfhNXweh1GABWA5YkszHfg+gbfBcPSgBLHDu+bg42VjuJgfQvyfWcFaprLdZnooKFscLxScc94frb6tB4w9/lr/vFiKVgUigzDPCxgjYpOOyux4cr8b1fweSF1JbWWZw9aLOKy0Yx7cgLrTUQOkPlmGQgHoYWjZkaUozYsP0uIfIKjjN62O3DNg8nVyyUgjs01A4hrlLyD5KEc1vG5OmEA0BZBynHrJpQuIKcX/cSyJ1Gn6JDwOhmv5WfmSOAc1zdurP/A6hYveHgnllsI0qTd1KEhEt25rqoQxvrPMnvBSYyqOLurXT+MSq/Y3dKDzab9oj3kQKRyJ7CYm6EUoLDXJA7i93nsq/GlfkLvSIGlOXH1A8LsEI99tP3n81zlTImrE5fP6AWJg9raK4plqK12iQPCKhBGPEUa8gAcEpP+Q46MrJU0XPVql5KaICEfaiXd277ZjXIJHptATBrcKDH73Ud+ZGG3mXaAOdE+3oOpc85TZZpLuAV90lq5nmkZuktZuxnmfz1aLzhRbBpFOD6anwRyXz7PEQju4LXpu60EVtVcFmYjUUBTPsgHSALCTzrmmzFT8RXAkr9GPSCCJUZOSJzR0pIQQOcH61zjdlZ0kklkNbCPBPtCempVICApnsC0DXkdfTCO2uJuis9+lVm5LiO92FLhcGysKNnefcKP3WhTB1vcFF/gUNrIbB+shVRc40FyN3igg0qOYDZI6eqzozUg3Po6wUGCCN35ljar3QF85JgEng5kWoIZikeFIRVnQBAT5nHY2btPgW6u/QwSqTyJGPmmbL+401aNVbNuAStFxHOeksavn/c9VRIly7Hq4zZ5CHtAkM/XgvOoGNWbWAPv9vXqNJP+x9l7U2QEkDDwdiMRm/buW/QkfWbzlg3UIVUODv+4Xlun5JHKJtydpE5khAt3ZHBXGFHmYwM2H9m0bJk4hPkjdckGR52f9kHm6GEfbvtt5KBpRRuAVm1Y/6m83tl3cLLqQxJW0gga3Gpi4xR6pZM+puC2z/2kEHaXCmzkPdWkglAig0qxcUQetCuYUJuHpaGwyD8SOoQ/0Q0+NnY8+YWsxn/FBleW3nI+2oZjdWN0pnpMkYtafqX4HphwbZg1s8dgTDPtosXjP1TUv3IvX7f7fBI4dooafYteKQ7KFrozRdIYrCaA8yP/yF2smU7m4Bd85kqkon3tjF92T6YQ2hMGzjhLYYN8aJf3Z+TfaEBQMY1yoo3a6lLYpygOc9fpeJwExu1D5ZWvioAm/cru2E4dph+J4sBbiV0RaHAHsGMLiy90nU8UeRKdvZbTMiIcyO5XZ7hb2gKmdGlx1xNybT7msWXD/1fALBFZ18wIWm2KuCnNEwujEOxSk8HWH8l5ATCL1bl9VLdTIqH8rqIur1sSpBtqrMUWAgqRe75jS+SUeXXSzAWjAUQam/e8mtJalJ7dAJ/g0qoCZxNRbo/Sv6aqD7qru+Mzn8WCZ62Gn2/RsdrSxWiAeC+6BWqO8vWFqpOmbe9NJp7gxsfl3pmbG7otkTTNyFABhwFmQUEFbzd4+kJKahjSQJuUMP4ZeudTP4fs0lzlmpLDlNzt7iOCrWGeW30nu2fmmue80G7rE3B7YuM4hX8V2lg+CNQE/n7abAH9EirL33Au//8C4/jOpXMPsIzbeK0ua3OiFDi+VPVIBnOsc+R38QDlUeCBC5TIxZAIff+OT7EgV9IlwGvp6TGg9WCiawHteMHe7C7SFCYHYQAG3T+u6CW2JswC0+L8RbyQKehMnLuFhJ+bG0XHoxzzPu5s6DIVjJq96lxlX6P4d5acfKFrbxWWe+i0Dxe+3GEJ/4rS29K7yyP9fxd5AfJ2aYRX/VGDkHrsuEb+8nQvkRI8ZttaQbzrve3Q1DTsbYjrE4tV6dyOAaoaCMBT/vzbEsQW4dHBF7FZy2DeNQnR0AOGmb1VF8GS3DfCA4sw2gsmF1P35UVTo0Nc5J9uqj9DINnuapRB4l0MW+ChbxxS55HPPsm5S1+7JsCOyQE5+Jwwm88XHMHhtuwVVy+qnIWY9wqQ/xCue5zpzbw7a9jRHlADEHTlTjMbMhxqaknhYUHRFwsWO58ikqPNu2+J/QdOzeVNfpePd8Ftt5D3O2DvbCgdzJQrYSzrczphbvRZGpr523qAjAZnpTorc1AxppR9ar+4P1l06tX4by8zTwAqU1y3Og3e+IwvVHcAjquWq2yE8MIkvWmInLd0ahjSyzMvM9VPsg7Kooq1Bihkhn/5avNnWe31Uwc8m1asPHUwO4qe7SOiFf22OgMyAbbJ6uM5f6jx0X7cVQzJUktBUHuv89pYFdrJEcHZpvLALL94DCmiluuPzhNfuzqo+g/xYYbgjuSaYahVVauztAiZmFyeexUH04+BYZv5Ukv/woUBVLGW4lIVauyxlAiS+OBlQinjkHVYrIf9p0cMvpKOXwMZvcV79MHU8yVZz+cLsRnuh7ALyxZK4O8DMx9MQsEUz0DzRB9c0qJTAMv3Ylk79r9Rh1R6lXAnv+6o0CGE+j7MVlCppqCMr6PF9oXIFlNrlfcX7ILf0jBAoTIgPG5RiPlDPqu6Otatj5+OBbUf6/rrlGG/zxd89MKWc/27W3aPc+irJ2B/XX1VmQOVSN6c5pkzzhtoOhVrRtbk+iN87wyGZ6FUH3+4c69OvT5sMBGK7kj2YehlAbRTc5kPB4Vy2h4ksabv/7M2usD2QmhYhQQtNZuURKcBXFp7g9K5DDc3AfEtrTwZA/p5SaE4/u8wYZC+W6vPM1nrvLoBghMBOMjaZ/JVdK4tYMlt/jSm57XRnjQpMNp8y9NrrU516D/00QiGda+lQphTQxWCsnJSXvXtxdwRIfS1tbHIqWjgqDGdcJAfhgC3riaTU6tRx+Mev0XBlODgT36CY0JsozvGQhUJEEtH+Kp2CWVzR6/8SDkrkS5kZ0AyZOSv3G9uMEBeRUPbTx92P6Vqy5zkGn+X9lIIsfc0fGMm8Jk6P52Smfsru+HW0UgO1z73Q181BdEQDo3hdCJEFjD5K/fuc/wbn9ihHeYmHmX7Fq1WDXtGmLw5jcfs61cf2o6/Ib1jF05Q7jnyMNG3rqrFIadII0LzoT6EUVjMnOMqFv+uABhiN4ZI7Iqr4KArIuJIlGO9IoRzwtiBZQZqzaIJ/saDmZgq9QwrBLK1q7n8QV5TF3+EsUvRrlvQcXylBTi8wQaH/IyAopWU1hJdbXaRmZX6fpudx1w0MLNSCxVmHUHNXNlD55K9C+BfNDK+HvnJCKYSzCUMAO644AaiaLDF/e6Wy2EuJ0n209PxaQU7KlTmbBn1nj1YrZI959ELzIWVijYfA7KtWI4WEAOBml1DXIxIP2BVr+5tTkO3lTP1K3W72FRapEcUL0FVmBYyzoe+kaIIkOHHoKDYTSufCGQFibtxkTN+6cX9YCl7ESeTAHDIKhREoD1qasRy4kW93qeiIaxT/zumIXFtbD5JTChpudctMDI8yYSGRWyAJFY6THOMcL5X0rIsV7CFxg2ozj+9VJUbY/D4YeFGIaKbxkO33bY2Uqm6w5/zamBlNaWbLmS4j3rKF1cmpZp76/xAgT7NNmpCyrXPugNW7T/bsHPCAukrBksm5dytwJtarlaf19Ia6eO/e91KCCL2pEjv18SZu5O0DqUAkyKUI+bHVUSxm6ABn9G94GaViS3h0Z5PIt3A8cONQCrRK8iMzLFP2ZPueZiAY3SPGqm4cbvESNVJ7lFbArAR0SGjwrWV2sesQy9u2r8cDHyxjqga0xAOTgO1SDSCOSC2Wzq4cW+W8mHoti2BSBZ4FiB+8IVKIuzKqkPSJ3aVSw7lcGCiT3qxPUMuD8L5QjmzEfO5hnETSs3Q+Pt1X9vp5tlnw9W+ZVSfyolgI1Aw/3TazpyU1uIAflu1KMbNAKtZo6aF6u7cqtSgTDo6+zRap/xR1IWmKvt4W+JCxzBSBiXYuSDxGiD0fB/HGyrRPN+q8qwaKZt0ZGK1YdaNbSqhBOiiXjQbkk0YTUIca651rMJui7fOPkzYKxr1VGjSj3tG/ypJysdH2qhETc8cuGjmKnfhpGtARdzJBN+ip74OQvOQ5KXXNkP6LKn+WnzrUQR7p+4Kljbeuw22I53dolaDELurQleJ5O/m+I7u0ch8fpQBYjc5GbGhlBumgqkHfaRrWB4H7ZbY9B3aFe3fMt/k7v/o/lGUXdRtpJN6KYaWgu3f32jTRnrZa11PL5RwZ9Qw5enMqgcHTFaieZQYNi4DFvAMTFfDXeTaaczMJ2IkGEeOAWiBB1froC72TGo+/EQB8VA/kcPt1Gu9i9Wd8xxkUUxQiLszOWw7iISZGgZcp3qXDzwi7O5UHkbPCvrbDPp+04D3DJwICfVleF6Z6F/3IIyJnB7xrMbz4d2C+ejJ59LLbaCq1ArfN4kyxS/OEEAnFK5dsgMz2+OCF9ft3W8uzJjPNVBHNbBlrdFOj7LMrvZaTAk+y9+vGiYk4bUFwOCrFIObwFPHHoTRGOxkUvsAA2HjSBi1kS5NbHqY4zZ0SPzhDZHpvinqWgRU5fA3fp5n7ormQAi9Nj8YIc8eBu00pnClzk+tGFbm6hY0ZpSMX56U5nUwna7G/ut5SuzDhfLVPp9/J7Bwu9iTGqFJKL3m5Y5AevKEqq13+TPHefka3BV9I+CznfmMrlCukiWIXVkIxQf5Z+9NRR3hJ2IRvtLnXJp1BVPdlr8+s1RmdBLuZMUsqvRxSKAuNsjeTtQG62gnOTSUcKbEVt0AKp6FyDmzn3mEc1itTTkHQm05AALO6P7ccd/ZBU2/oI2qBWKRGaTQ6jyVrDbaqAkd9dkbNzXA6rjlVY34UF+23lwutv9umbSZuzVv2bBYi3MT4ZPgymE+FmZXn5xE1m5e9UE3vixuRhHVDB5/KdY5LOrmIrKzjYiqkAdAPjpY3XAhB2qSzk5t4bPOhzYRZm3T7O76q/70e2hUwu2vayMNc4kZ4TWbVUrSmsykuIEB8bJ9SuEgJ9q0EIpKeitrj8Kfw2gSZX3PHPAU+UBMJ28twKtFBJ1tSO4BetJ7l/BfWZyBOxSdS9sPwX88gVgwz2OcNvxLaFFH0hNOfP/85FX0XknW7MHEJ50XC1RkUyv2912VkKxGx76OE/9U+vs4PZZ+JbXz2tCBAIttEKZJD6aJNzhB9Bx7yGuLqukmM6bABtcfQTI4JutzOnA6oAJPKopAYB2mQgF5wdqXAzDmnaTiwEp/7LD9mhHJLHNYjd5F9Tv+eD2EYju7PAFES+jvC4igp/w4uaZfwpNr/d/2vNS9kOaGYlfNbHYCbYvcf7uo3HaFkslC/0Py07t4WrwxCZ3vzzPeeXpY61bQXplMRWpqH41R8YXKp88oUuvMsujYaEIFfqb53rE9kMtrrjkb+6cysJLSnVxmA3lObEC8th3DX4OyC2HHg58SViFxxG1E9rFsbPLUcb2WW/m9guZKOciGVDpO5YYbqUVgEFV7htbwRj/Bs6/G1A8VzC1UHtyjUJ7puWBUVPb8J4A1O5is290lXCCutR+7tW6Tc0XVqEctClnTqyEKT5GJac0JdEdCZJjRxJgLaVw3eCYFEmZxrfJ7x9l7gbpPzeFQT6UWpZ67XUMidHKkB36UdIO0sxqybNH8Q5f7piBqqbYh2cjIz+fd0JWE9lxZhNt8Nlfdzj6537HOXb2eSuWVLrSfo7xbWoSw+0iL5l9G9merkxeIPHMjAUj5kqZng3tKGGO37DLeOrSXrR/fkupblH79yR0jdOCJZ5lYqAnGiU9nOalb8ntHPWDgwHi0GDU9bScTbcmG1bDAy1ar7WKfD+U4fQvrHdi6yhAi7Ydewwil3scXzkOP6+t8uMLK4Loeq1Et6nWqF0cNGm8vBobF4iHHwdpGm9x4cl8vJ5zhbkIzNnB0Gmwr62f/lyWnM7pGYlkEwmWc9U8cgTNPZiplGuW9/944fKY2H5bppxEfcbvKIhVJUVLq0SahOQW8SX2JgrIZfP2y3eIidBfnO/e2HjVY2uoIJf02QDjztmH+osbi4GJT9xwpoOn9M536rhSCqw8BrsW75pffaG4efr5YlUO8wAWmhEAuJ5iYNR34jldPu828wazZ7T2xnyzdieTSOFP8IZ06B345QpY1aw4MZBDgx02TzS0feXDU8eNPy+Y4hMnue3fNt2CUKBuyMlcY3OgtDLdlGJtCvibRnDJOVxSfeVPFcqJhT3I0NIXZZfsdyLR6so7/WRFmpgjrxTc5n9U+Y4ZVq2u0+gshxHw7unC0IByD9DiBbCfuMsUArLzY4mM9214rR8oGokM36DGMjVpq1IKmR9+brKz4VMamM654ZKQcw/skGg1DUK1FCa5VCzGZy750sMyheWFhQqD0LXzHfxmlS57I+zPPeSEfJ43knynVvypeGhEflTxbHMGuVTVe/k8brSJMH1Rbnhcf+JLTTt21JkOhBVixZNBEQaxOmF8hncwLk+NzgrktPV8m7cBs7PFSb5XYyh7cCrkqRGfIHmRMXFwBhYtqN+Fdz7b/1FepINJfiA9Yo1lc7LPWxW9phdWmLlxkXcwn0xLEgf7l3axeb6uBuXqIGfrVsY51oEjURUaJbFH4b1upUyS1UDwJg5rhwjyX53oG2iUEx/JGyvhsepftdlnY4XM9Rcr3vasb8Zm4djHao/wXAyBPr1VYLTtCEz1aKFRqqeblpdWn4RWdpYdfz6ANYXg3Sf5LhAMdgBsjUOPDL51ZNPkSyPM3imhAoHn1XZG7VKUXxH4Ysaf1PDsVcuuN+3iZl31ZuIzsK6Ib9iEJZeqxZ5dUxbfHikxYFCpf3FMZt7HQI9oV0NxLIAOjmZ5PwK9sEzsmbARZK5le0E/lmA7ar3foYUUrVDefmeT2rvynd/hEp6gb/F78AHT5VLme9MmwaQL3WP0DgXWXmf0ntR2sh1YkyPMyFNWEXFb3ARnC+QaLDncnd9CPC89fSJXjwU4W1TCr4lHbaHswlbzU/yJI/VveJSxuHTDt+tPkoLz9HJKxIR+dFM91KQjXfEAoCpwXWC2AehwYzwLicqb62nZzJzUHT+GgGMKIzUpkzqzpHJ8I2UGg3PNu6KOGWY//DeM7exucU/SYd5Amg22s3ijpy24CQQWC4Bl5auxe/G6XtIb8Kc7aW9y1SPifkZEH1g824mml2BOUJ/nX7gtDz068eu8ncOfpKNd9qRPKVGO8Fx8KPndYfTDzUjDEMFVHmtHNy2y1DkKhy1o2/C1CvkBsb8oNlnLWXGN6iEMaiBQQqBXDPb+ZoD/aROopU93CXl7Amq5pJvfelbGwBTVFUadgEPQquJqPlaabWtrrGr/+ZpMM8Ew9q/Dfi7wm8NtJF5NPqO7ppHH9jG+GbStQneW9htut4i6uvAuec6Sz1Rne5Og7Hako6mjN/Vke24jtVBF1IcB6TFmilgc/+GrHF2nd1kNhVUsInZhdDJ9Akn/Q68OiY5zSQriR/Tt00yFBfzwAUo+hsbtqQSWS0tE/GIovmzJJHbz33EsdwttZUhlF/yQj+Tjn52Ng2r1hdCi712h2pCtyxXg/GurhIGf78FCxFYOMJpF2I1RSTzW6LjVeo0nCwtMhR7b2ubYUR323Lx4D1ZxlSrRn2TxN/ysQziXSn3hG5E9Kg2jV+wLRq9pCjTJRpMKZEkEIQjnXuNxjIkIMns5UXwBZZPxsPA2RsgCdwuw/3uda3aNsSH7m4RsOWxOGQ9v7dP+sATq8eumoRybcLGU0P9po407gK8+Abkrn7DE9dT+Q0F3HJTHHl/rowbJ+pdqXkGxkd0jD6PnjfdMU7qHnhcZEC4p5iIWfBj5Y2DT6/oy6BMet1cHH3IUadEJGBiPF7NyB+pHmHAgOzD2LgKYMVB7ocKcHu6hovwN0YdL+DAv4LHwLNZPDb3IKSwETD5j0RMuca/xj+uN0D08vsY8DBycEnb5SA8MYIjZ/pfI1PE8z/FvIJSjkfVPXmUxJbnJ1TLUwMc0PBaV8EggOrgv0/qbBWO8lSMy2F3f6nVHzyvmlY4BcPJjBI3HgOQg9rTHdioxyJ6sJE1hg4lBqowQskbrY5AjJC5VSabqmgvsaQNHpMoOP0mPfS53/jkJ6HyFKRRbUx9fKTiLS+Krksug7+2Ajq9VEftv9N0m9LTpI741Ei7CzxyJLZqx5JqwLd9rgf3Og3s3ZMclNpmwITDpGeMxwyK3DdHfYS/odAxQPM20+QMGvR1/5mQHhyudDz9Vg+zjg1dzRdVT9JsX8d0vLRtQ0bKjCwJh20thbptfbCnMGeV8nJfQAABfnOG+LsyXnOUv5wXOQ4AeC+U0yLFvgZpWukMtNuEKY7aG/g+U34SMcteK0DzkjZxDwz5SmaOccyGW8hw4GMZCsXIUGLkheeAnTwT3cR25llU1sBAOgr8HRg5EZQayQ3GzLyXhLmqaOdQv4FIX7TzQThCJ/y8Wb139xDwflNih9yRPF3vpNQhH9+PiU5YHMQSXLHNMx1Dq6siTIh7L13+wexYuWdNwDjKK8xTE6BNOQ9VwL7wOSPwwrQ3oKSRHiZ4T84AcrXsSmERPfAQ1Xl/q167qX0rUMOdJf1KFaEmkINqjlVH1nuN8dI/woaVHqRnPlrYTM/3y5tcUMj0IfVFuw9oiCY9YrxT0deNHf0PHtZzCkipH9QFQGmEr/SyBIuqHjfzXEwSUi9WruCXE/4hk74NJ1thLOWUwSvKP/VK2tmJj75kSi5fe9CmgYFhRxoeOlo8ZM58SyCR52ALQTPan+ih9RtX/ydRQuKyjMn8WGMDlaZVA8F9dw1F2Wfw2ZnfdZFmnDTAz3VgRm4pMmTEqI7mF+Fv4UP/HGJA3XrkdjwiXfQGweKYQDdWsdDMPMULkTFuAvmgANGvD0IGtadX3NnPriNaXrGi3MwghxMtyFn9gOsuRlor8zqi9J293cf9qXPNLAluhUl9B5O0xeYsPnqfrj/F+TkgVP7O2ffqiyfyWmFcqicbpcGprcteDCvvAxSKgy2UGVyD8zfFzEp7W3kTuiAQ90ty8zIrK9QkwG0/O8pUHr8uRUOevjgNMM1BGih8UhfBiwEDHsKt59Vhmips9E5HC9NlBnHXqhM7naezs3O9czPVYGvF3t0FnS4bZ7kABG6qS8XPyinLvF2HO6uH967fEC1MqpnIaB4jWmX6L8ueZVm3TNk13Fkm0HS9AWstybpkwXAKmCGQ1KOJS7QJJC8NQfmwn1uXJjLDN5stzH4R3zCJD9vhbfTr0eYG8WxZZW8rAwF7YP351NRWqB8DHiYqocnVYMV6hOpkwJ1VDQXPV2v8tUT/nUwEPPA7TvTug9Rgl4Zo2NgxiMafOrAIX9mKjfG1MPmuZLLPvcrMc4PUmqNr76DU/mVDXnlk3UPTCUqC6gqHgURsNQGkzwPHg8jZz6HlE5UOaO3JxN2iHp1AlCtZghqaZIYLW+G1uTs2sCEjyf3cGoYQepvnIlkrbynRiFkWuclckEBFWUDqM5bua6vd0pYuaRHY94Nf5EirNX608XXbDX/FPIHUjgbStwrR6W8dwSyWnsgn+SQKb1x2GNYgh8OqnsU5Btkr+fq5dyi2V70JEzZRj+A9jjhGTj7LJa8R279tHIAWI2gfi+Fy2tyQX3aTzhF2h1b1qEgr6qJEmDEdLz+ciK2GqknethItpf7HcrweTDkInmz3t3piqS+CMVr97CUkHstGZYTlBvuDVlV6Fk/2sF1us/iZIrRn7KU3Y+Rzj5UxR8lcG4BoakA+8PwxVaaOTGEEMfIeFwq3jQCtew3uwBaPWp/EgpW9XR51w5ow4lshvjp4fVovEMNUvyMFZ7ySHw9fXXpDkYR2RhzV87LOho5kzz/ahgzDDR6jkCXBpO9og/5+raeo6ykBQWUYgoQQAZZTUA2hOS6iSDTKrd9mQdWOLaQxM6N+8lw1sO1NNLBIdf9HAF5AVXkpAW6kvi4yC6+0f75Zxt6ctIwt0qOTE6E1kFTGLhroR4bHyPGH9DvLpZ6+RyVDTju6mtpd/elbg9X0StBFaetd9Ql+tRuMvezXeoG/hAWnpZgkksAwYFT7vbAgwbzhDAxYBesjDd1w4tRdNKeklCnaILl+oOcjBXHLBfVEhAZKVDSDB5n1Q9H+cMA4nnIwTYTjEnWMXewy712s95QpVAN45zcl1i2pqOqQsau4AA/0MG4Zd2tfEb+vnjqRrG7UL1wYdTSgCny0KTMvWGDcUNHDbc98GjzOppizJdR2ohwEYk4iIPVLuPByjYGk86hRzBljyWf1LlDFDd1im0OsdNXytPqvpF6A7ExfFkeU5+9x8IjKydf4wy1avmCQdrLQUMkn06TNfH9I3RlZXg2rTg4U6bBmogu692HXHCdP+Ln8CZVgAlRqDOsWUIIoNUSr1Q8TeTLE1XQN9LpeCgCicHz8RcspJpin6MRHrnVw4CBD/iFdZagQWQBRJo60a0kaSV7U2CG0CT0QD5nxoeErjf9c/4z+rfxLmJn4AI+PZUhlmF2ShJ/E4U04V47hAAhokgXl1aqCOudDiQWpQckmwwfifROfk4Lu8aDDM7xC2NmLauOy2bsy8NSsjdHBn6Z0GcqTEsJLDOqCx0dBJcPE7yxwpXoWbXQautEo2qO5fGmdWXF0/vxkaOQlIQlQUOni82pqoyq2NSxnlFDpwYSKhzEwxpQXKufbiXiaFkpYOi6cnI+RQ8ckE/hekdxuQYb5/vT8cJynlnx+eTA2ULJctL3nBOYOtaXv/tDXj9DgGQMKH0KkBZUDByh026cup966M4UmheDQunK8sWxyejcd0LWsrgT7MR6V/9NhvErdcI9fJuJdgnXofg9HwB0gUBKSM/QmzTMKTbS3ec/aAJO/Kl3D4T3ZJjyhGsOKlP665ZG/Y4e5c+8Pzpl0ALjH2r5qQSQYrBcTzmT0XNtU1HC64ZW0ttkIbI7cmlF45nMtpgjgZggQbYton04mnvm2OdOIWLgK/Tc8R80VWZpaw48ejdzJG/6VMduaGNNNhLwGxbZ7FDX6zT3I3mWrTjvpP5RO6OcWfwT0iBY9PjALuuMtKjXSm1Ir8EY9II9iU4DK/NGdxnaaKHX+V6fchhoYZUrJpqQruxuK2qyQh7HzhscS345wCe0/QD3WDJ/kpWc3T1297WRcarBa161LJTcWVduN201tAQ0c1gFzThWdQeovmd0dNBpDq1o8lt0lYvXd44Xct6rj1ioitmmXYT0pQcFzzx3rTmh5AOZ/B5KO0bRVapggb6XYvFNyco0vRTnZqsICanogJD7EusekLbvVfMEZSTNo2MpUdHzsnihz6dBEPGF3CmrOjK0ppm/zYWj/WesLu8BaKoPTujOF+H0cc0uBOgICp01z04ZJDWXhHYurOGTd1laR2YgM9mCuP4M5/3Tay9eS5hlSQiI03BLZPXyiEVIGelOXwBbDRy97owZnBzfyR1cl9t/hY58haFRIYLpe3QTwagxFzAppE6OC97m/7TR0pb7kQEhDwa6xRu02Z0yClBEnlVV6Tg8+jxfA4MbU4/eTmAVPUFtharcwD6V8LdzzI68ybsED15Gv2VxHwYTP7NyMrFNoHUhbrof8wrHt7aNdMrBT54Zk/NAmwv02D5IRbviiagkR5nddqLGyZdNuaMvILQPDXzeaZLj1fYX+dgfYX02952X5BSfFSrsyGgfCdscgR8T4paVfUY1RcHweekPjT4Xl7ohiyuNHiqkZA+1+DqF78iisrd0nkXZvn4ljLJQBwAAN3j9AswlhNjjt7HxABOAy/clgHDgC0e/V9FgqHw473ztIeSzvmKeW+CDxNlrSK1Q0hIHT0FMrTw1usqs8GSNmbyGg/xbinLokHROmiVvF1IKwJ/xuGTiFKqjcLk25IpJ8BClTQACEyeLGB8MF141L1CRkh+AvWEsjRAA8qG4OIZtdjTX0Zor8KhE7YQU5rBscRDyJE8D7DWSwwQk+IwIlA4rrdEtScrlYiTIY9Eb1a59S/u/7I1ZyHhlZIrPnoYumDkqWVF15W5WqwHB3c3cjkOTWNsjrnF84A7IqnUcPkTwVdbyI7ye0wEd7gHc1A8oL6XyX0Cf+KBJe7qAujJjsbPt3nKuTd3wIHwIxNRsVyH1prtMkQhcBXU+5miLF72MRTH/xe1jMZMjAqnj/84N5SjbfCN2NBj68r1Zvnm+UQjCPqJ6ikt6DtswEd5Sp39tEti1sx2fDyOq8asATOC6aGZUiJMGmsJbkqUtQeM4IYO5WI+r1ZT+J1QfjRRerAGQu8lvanF9zZEak9nxSmTeNNgAAECzEeeZ8hWmzyLOraPwb/nv1LXHBynVLEdlwky+iCwgkRVb9wuPlc327TTvnGJILbZG9Or6QJTeEucL5jwsSiB/wKduH28N1duRqDVURYlgjRoVnNXEggVSMFXL5qJyOEOwcTXIc7tderupMkvudPqxrzryhvRJBTFMiywl3q9Zd7784xNComCAqLJ637XEBQHWSA/gCCoINWpESxbei72B8yPUoZKJzyR/lv4PJtlVKazD0EI/j0GYGoum10x3idyQ6vHhCueLFksmFdA7q4ODD/pgaJbN0yTa4muZph3EVuFCLJxuSw4tFoEI7oDvX6nmHgY704rPVQw0XBxczXr5eAPEpRWgr7fQ88EFipHfFdQXmA1gneMzw5SqAylk8DI/hBoDtNjDcd8MqUyZzNRj6oK/PCxm+JqcCbFLnQxn1/F3UBTUxRSC1a0gsVs2NrRGhyYk5WfB/qlPssTguDl0swElqjrJK5bXnupVMxtCNFXUCcgzotrxSi03wffimXLMAsqAS4cVGkV+b2BWj5P9KQkt2exUOMMB66FYxFg6rkfrgMkszcVhEv4cFgz8XSh20F6VfRwlAQUDNXx/jZPL7qRjx03NCwhGFBodSd8BjlZJb1rTPFgjahRneyRJdzRlWzTjwvobu5dp+YbxSJo6ScBuykLUIaPolDsE/u9q4xrfQSlxGiCeokkESsB4v0EYb87JdNJj8PcHeFY7tbDFrzATTyyUFryiez1eLfrRASl4MbL4+Nx7AC2bsc/0zt0dQjbvoRVfluxwYuDwshSgqtPW0tegWs1wbpeQCGdfVvmjLvlOzoPdx75rgbxM28cth3OMTzC57jGa6TqX3fZDxlCdzOkJB2pl9Lj3Nf0weX83gpPtdmmgcNqQvTVVZnr94fn/3G5WdIii63KYjmcc0DRoA0tBOh7orE9BUrO/4ezOrkFwA7zEYBswl6NZ8HFeMZcohWuufPD1ahJiTT8ejDtpXHe6oyfLL8bwaNdeXYWOh2PuLolipSpRTJk/GbgozaXhzhR+WhlNmx+H45y4Q9CkvR6OmfJngcCBhL+0TUfM+KXwKZi5XifUO91EhW0AhJxLrZEEJEH3aLXj1BjCYQnjZrQG6JDuUGB6Dd6tXQHuUtlveQD6shqpmgTIjPAam/uhRKhyBO0tTJF6/EjCYQZQx2rWejDtji1iglBI27VQLYTZNtnufJhYhQyXwnFj5K0HpRsFZpFZT3g6a8Rs5R4lFBVpsfpLVra/kytTshzfWfhop+KS5URX0NDyB8ww/9fG8EB3EZiwp9uxiB3aQeLmFGfkoTnrXdtpzL/v9Pq7E4dQ7TlplzvSWaq2NWzhju2zeiq0qjhNxUkinTGLWnjBfl/70hYvEGNWMN7qMO6DQ4YFrv45IOIEAoLUyiC5Jl7O+Zg97xBThrNlhxCtLFzmhNkqnDeURFcGA5WlQCYHOSIPuE7xODw3pMnkHWrWJ5KnvCAnDxTImYdtGYsB2/iTmh/w/Efqq/yK5M8fG+dDR7g24xq2jOveA6KGJ6RWSk2FxLSFvw34hWbdHgowLQ3ayR+eHO/YHzgTlbdjuZRAHIWOi3LHPjv9qkB/o4T0VtD5VbJFkEQD0A3uaIxpAeRQHC118kQVD1ywym6ApEiay1UUmhdWh6vm7itbucAQE7gypbdzvxMtKcNDkRpzXx3WZEahIBqzfH7nCbjYe6hlz81zlWi/0n5mbqZntPbNBMKcz5HawDvIZpWu6csfUEVSTYWZQ3abnvPpiDppCe5XrafxNK/ADZWR6c0ebCyPhhwOCt/HJryCuIckpC2E+qV8CEsMe0R83VI7fdiRMdlhPywIRqsiivGSwD+upzXwEymSSGDMjnDyAbzOHx3iD6Zlq4bsxlaCryv+Hlqoo4nCip9Ev9i2jCnr7OvLsr7Q7OmxZHfRXdK3Z5VD6C0IuT2Lne6++AtaxrMpLGME3txQFAy4IuaJj0v1lFOJTckpgYFNKBT4kMDNueJqNIF5KGahj+1famItZUUiBusJtMIlXBylrTAf6ftSD7jFpAVwup43O0eZDL4xAPh+nxqktF+BhS069oYI8aPAlvYDHA2CiJkav+FLLPFSILMSTQOJ26z0pabYQPDamYxiy/759n9iVN5c13JqJPoISXdxwlEV6mKr03sb0atmD8sSAXZTFelooAnfpahCckrcNp4g0vc0rGL9iWLPH/Gl6QF4WH9a0pZxBAmtUuQL7gOnd6HRV5bxd6rHteF3giRZwTT8WK46F+G38N1VvrZrwaRMhsQl0Lq2IEupxPW/pZdeQhGMS0bkDIdk8fM075QrPC3FmTeAxyvCykr7L/JhF66LTtgOf45gRmx1OdvbVlKbLwQc67AzsSxoOyLo3KP1L4xhmB3I2qHZdmDlVw9VX2zDoXus8fUC9JIwZdzfMJ3XK/2OElqi4F6PCqdD3bKP+gBlQgdLx6Iaus9BRkyS34uluh409Yo+qxHs+rviakYwno3MCk/rTbF1TBp3ypG8Sk1kvmuT0u4oX5SbNxXUcMB7Xfx7fItfsSuSPs51mnR5s8T4K2loHpPBrLTDU5Z5m4y7ki4djvO84Fv8SmvyJpZ+xg9Kpi7QP+WYalh3rQHBMxV7kJZcoyNQK0XhXUGLTwxloD7VBGn/xyVv1KqVAYClBtrzHanmcUUGhyfc+Zj+HrZUJZfDmd3MjfrVXbWGV+HwfXwxAynKNE2hCWQN6dPu1t01BTUnWHXbyvqmKWOyfHuoSk4cntLgP/jG5Rtl5i94dbS2i1gMLGIUXnPqz+24AXsaHfuZQfarur92OW/t+jmOHKiiCbykiCFrp/5hi5E9bTZZ3Q1H2lXt6jO0q687TN526hAip/daqzBiB0ixxM8v8q2l/fabDXRD39f0ky4gU+yczJg9GT3dZ2RsimqLy013I6lm2bPwnP272socACU8ZLRuDs6d8rpXHZ5fChNYYscpJFN63qS2yKBVF4degEp4cREKDfN3MOQPkZN/U/mPsIGF+ia/MIBIjSQNJpjJHs0CyQ/UaAu38RWWyGSS4UYSdrEb5poNdK7+Bl6Oa9rMRpHTEnNVRS2us3IBNYb+v1B4s97eeH5Hy13q80P+X/U6Wb/0pIKrjgMcCI4uI/BkccHidBlDOataDwJG/YlTEYfqd/IdUjRH64G/6jUQYDplHAgYBGHqz0pa4ZzR1lVJ4Bq/20N/pjROUbLzVdV583HaPPq/nWteHwuOy7QHfZt//0H0gfTj54oeA3lLU79RAQ/R9Z8Pe9uPUmp/YDwSN+ab1H/tUb0hrUudXhx6a+AVLhp26TlXKmsZwfyR+4HlJ0cuHmV3LP6yGwzkuBSipDCET3KmWDPtpfm3KKthXtsM0UPwr1tS8GvZHB0s5hgh/Of73UOz10hCE5n97l18JKtkOkbBLQradIWue/yuL/Tb7qc1/lv3KcbQ2uCgGvkR2A/vV7TWracHNDx7UPmu5YXSg0YSWqSVB7uofLSuoOda4PlNZOSVcz8X3qyRrsq3E9xsjtdAjkjOj7diPBU7RQk7/hsgjWX35D+p3/aSILGnGOkyxkjnNEV7qy9mmWQ1myBLxUwwhVkrwcV6MmQO65FZee8q7tfBQ7IKPReLUv63A40u7GhT3+Jx8xJyJjMsdth62WvUVU96ilunmQcWs5wvOZ+MHl9H0Ae1MV6xl/MDbWQ9tDJK3j7K326H5TYrPVER9diHAmffoh8rkT0xdAsYd9s0fz0BnrpAOSplC9dciQ9XbygTffkY9z/xOwPYLBYoQ1DhAzdlskVlyRcsQ/xjjSbyaxuApAFehf1KojGlTZ45MR6JknoP0M3kXd1BCJ/8U250KbPLVRM/28Pm8JszxzJHL9oJSE2YaFI6839K2GnAOAhby3nNjKjFwrDLr1PuH1mFhmf+qaT6Elo5DEznUIKhGx3u/ilE6d3QvgC8Ip0LVgtstCpcVqcQGqVcuaCFqVugvUsWaRldE1nDIsS8T+qzyTApFJwOR0Zx/TNNGnaJD9hLsKdsISMKTFdbVuuFaywWiVuig9vKfeH1cjITZzOlT9MEOYAOF8lXb5DlOJNzdh0JbkURgcGBFETpHoa7WDCiwapFFKgOclmrwySBsXV9dYd+gGjClHzhAJ6Q1PW/Vo/S600xvCwFthL7XwJQ2HXxJtr6pR19Ygbw6TyMMQyVBu9a+LKA9GK0Pr1xLI8DU0Wx1lvyk1YhJ9jTaWab55ZcQtPQTGuc9CTb8nb3avyUxVTYsbuFsBIodNby4IOegpctGKP1pvCVlfcwo/n5FylqbSkS6Dwwk7yCgV/59BUZ3NOC68nK6by+XST/rszVH16tTx2HmxrYU5KCttZWSZsnKIJ4Qc2HV6PRLIlBds9PQCp3ii9WhY1ijTBjzaVkFs83XvLFtMgYL603Xn3OHLie5iWU+D+p7ZVJ9jOH959aDalcMu3gVNDyH/vvAa2wzlbBw7xytxggcEpUcf+RpHuePl8zOufWY1jrrHzFBGkvvmhOWAKPH3lk0hOytvxf8kAdjjrO2K2IOcNxlS6U8IFcKfEDVzHlEJb4CY1RSnCXP1RYnCoyXvtkrJPosloQbxgSgn2dxjBN6dq85jj1NbsSjVSE2hdAbqeGonifyddfsjCM7BwctuLDVal0nXwzcCUBwvjMBBg9XURvceUNJXhGIVq8+PCteH45PT4ee+NX6WwQrG/lntq0qDZT5BjOj4zYyMCDceqZxVAgjppYDW3d8BIkBloyR1fNFFXTJGwQu//INX7WFg944EXaemdrKFyWXH9F1xTBAcq9DBkDNP/5b2GT2CpTUs6CFp47PmX1MIIuHFnkAAi6032wM3f9FJplJJ2Oj7z6YdxW1tbPM5oMPu4RtYWFEroBO9z/mxA9DOdTQXZLDO2V27gJeiz18fg653AZ00z/WZsy2NNatH7dzXqzhIBeuNiOpeIMwGFrW4Wla+i6/sEo9LtwuH1BVyfbRdNSu7NiqpABMp71ErlnkeFumc5y1PROkqBEmVd5Ijfagpysi+yncseV2y+Vmgp6b6QVcBxNOGFrj0OLWhYLW5kbFzsfHIXn7D8byMMjgO1yzNV3A5QrXK0Lgfyr1Bi02Iv3JCVkBkPkHMCvMXt/qYeo7TWT6XBLsz48t1vpetjtvJOL1d9O/J/cKdnLPBkEF+JgCV0mz0QdNrWZlJbIDm95tC3FB1YV9xToPIXXqjwm8QpgEHr7bPfT3j932ywG1mc0aREkYkbBNlLbhFT6BJMYBC6bYtThCFgO0je6Fmah0W8fMfT3xmuyV6Q/7XkgxY4rjiGrd3jtvDLSMMyk2NgqZjNiRSqcLeoST/6UxgGpC+Qs1F3HF4MdZuE1q+3Ru3LLEmZOCxJnwfMbrc5RZTkeoRR98CXzcA+R6hRPqnKGEyeG+SNOps0Trr5pJTaVhn/0pggQHU2dST65uJF+JGVJ6WWzYN1hysUHh1C8CkqmOROu8HkFtX/5ySXvh0MsuRzg+Ouu2XUh4RdDFom+pzdp05xGn9NJ/+Luojs4ze/cw+MiNZfxhckC3jbcCHIxHMiWwjJR/L6N5KZ30Tzkp96ZnCamUK3CCyRl98RuvG7pb3kS5URy0NpAGwIB4F1hh36iDKii5bxznlqO9dagqdBO/6pOcCC0nDiReKj1089ntHlCinjNO2glswvGZNPzk+Gw6lnjKtfPMuigM8UG6NQttr1prAR2AtRhFbf8rW64W8L5lQZV6iKjRiUsL5mPJNEjNP0dQoUT1taIyH3S4HdR/YPiElM47eSyII7NyhJaLy5tYvLWK91ss9BgZ/brIUJ1+h6z0zaKS+7iyQUWMzCajXykadh8S4eEWzldNhDiK5PKkBNT1UCptLnsEWaX45m9EDGvkJWfGPmPQJdxsk/PNBH+Z3ytydOEi9NHGHB0soIS//x8UN1jt0TvwG3bgKXemDvmbjl9nSdhatj9IpAhnNBBMHY6lXRXTwUVjcXAcMKz9McBK0PwZKJDfkDuJhtplDad9FCD+uuK1Q35IFReOotcVODh8YwXHIXIsbLOxmq3viH1Lr6ksDYt7wZ8LA8HfiIUqwdpqkXvXlSIbYYcEk+lstMxLjMAUTO+SGDYY6rbDFIy38731tDn8QsHGtpGd1w1o/7uLzEagPph2Tj0ttFI/CncXyeexBJHd+MEpxH6egWL68dvjx3BLpbcQvmzYq2KU4sDNNFSRWHHeCjMBS3VBOPkj5xOmq7PYIcy+TCrPVF5s0O/8tDneaOTDJAaQHUR0MqzuH/fiIRSw2cWlPHxNbl0J3L+yEqvkbCbehZKG4pn5yg/l73EkuT+Q0RiH5eMne9/lHZjBI6BsRJeun7hoPE1/YaCtRHw4Ee6/8gzwOgm4rxoqmesuUseNYRB390SyPDx3U9wSvra/AAlxJKA3Uccr++IhzVOeOtuILogplpR5bfuU7Xz5zM4IiGPm7mNCLGuY5aZhOAWbgeXJXMOAGnrtq76n3YlOyxUt7FOrLG3/nBGon4pMLvyGGFcwZN0ufkzbn1Er938Ix2gWe/BmQPhHDEIEAf/jBDgaMs9QCRfx5HIHEGf0qfdmHdypDHzhA9u6MqEADRugOtAuXZsVQWkLtvAQD1qFnvk93E0CNPMaxVvSARF1Z7xgBS0YP/MyAi4RoQm3lRwM5t9Fw7FRrnefHFkEsPw83NmbuT+mbOjM+FnEnrON1Qi1JPBqacp5KmpG0AbzU4rr7VLMHitAWLPbGbdpb+YLXqJuW2RZT280+WDRkCCx3LtZtzETbwTgPCsQOZ3SuLquSkHdX1vlkFUeYC89cxs1789Q3Pr4MiHBIX8zMBANlf1ahDvakiWpp72OnV5gv62Vv83O+hYHcgj/iNEB6EYbJzv1A0giAedcGRy16azUUo0C7ROsy7ykuZB99Afl+BzkNxSKV6AGds/4C8yTCxB7ZYYXBt7jWf2TOizGIlKR4J5zBh0E01vo2GFYCzeoD+4CjafRnBaazFaeShVlJzTLC04LXn/V89Sz/7iGIfVz7t3Llet5IWgQQMLpMZlQoERlY9MPP/MqQX8BtbriNcrRHNpLTOtZodsX6fxuomYSUy9F/PXgyu+w7mE47eJpZBOehr+ON53JoA4oSq/NTpUdiJu8+AYITJ0amMvdFe6LoTfZbg5lp6lDa92qwsSm21cBmMCI/wQEWYLtugyIuqnL/TTOhnIhdfuj+XCCZg+FsrIW9CUdulp6GmmnbUhpEbg0b53UlDGSGCcVjdOw6NOZjTrG0cBtDS3OZyPtUnXgMMEXvn/AqkbUt8WEdIwP566rVs2djRfJHDfdrvGG7DSHOsbgAOqQFW7eGgXDwSnhglSeB/webIU9nlEh6BnVNgYHIsYiFxFR42lvrrCCXssPqXydrhEHU9MVeXdcyGIsup1/wl69FnFUHJJU3r1nFSHpHjgDCaZZ4EhEV2gjurEtFu4/tiud8oxzcKWMkwp5Lu+m1pEWZAasVwqf+FkA9cE5BTdwlm6nJ+q/ZL1zwVgH+tiCksrXkclaDxFURdN8y1M/vJYwDe2h2XjGgQlCqGxPkZAP9zpK0sLK5WipvhWG3lDqlOkiJDP3Ty8UnNIZ+A+VRQrqw0KEymnJdEMU2PvPa1zxdiqTGCROAL2HRGdvWNnrMtXRVdFCkHGwEEh8vEW1oVVBwWOGN7QqB5g46iQrsuTA7qUwQjRb4yhiGSEtqJptswHpz7/hBtSWnEsbCnjwUSKm4bqJafmygbj8KL5rxnzrfX2X1KMVBkTn7mK91nWqHAivkoE5j2Aljff5DAdtf54V1LlcbwMaTvycMbb1BRl35ba+1McDxhgFsShwP+X262gF11yfxyxsuK0MM3/14bujNrCFGBLElwV/MZfdLPOZBi5m0AlJ7CujYtJDaqNR8QifgY07b53CGNuYZzKxBkHu5mIkNzb49WAMh8TFCbUbFtriZKUctoltEJ+m97/W6EAB3a8l5Vedgg6WU3pag4/8Tw9Yu0m2XkIW45maYpclp1V6mxBfIDIPaNlWtjPCfuFZWxgq8jtylv8Z4eVioyQZVFkgprWk3O/2WXN6u4yM64Ng2M6dw9ozqyj9p/fuNWSuAl4rDimF7ALUi4p9ajjXrE35qdYTYZPlpCDJR5JaGDrrA0X39HyIN5/Lmi9xmzMtv794UXBKzTYFGkTA/4bEzb962I3UjbWG1VMtrO20dUrwo7yhjQSLxmi65/apFgS9W9mwnMFFP4q2iKyYosqNLRbWxEL4zrBCDDR93l3MbWsA59mf4eJCodyefvHtBssgpHMTTxkTB+D+zYXReF3YSRW3icKLolGdQj55vD2xyHSVItu2ByMyuyry5nPm/N3lOG0zQBdPR8sDwjJd3xR/hWBCyDnEKPr5bM972wS5y6Z0kH2en+0xG4sp2iKnBG1ticJ38qKajOClLSUz8MdQihITzHCEpPj9P8C3qf8Btxc5wcLeLSbfaEGcTInNfauHwVrgqrOTdBf1klIMJSpKIrQ9YaKeEz5w8VxIXI/sJkOwq5ss/QGGZpvywybQDpsRMuWMUuOusU077/y+TO+XIWnLjFsLFQUTz6E14zfrW4W4aKaB+WnguQ6r9XqZ2GxThkJIoxq8w37mOJ91iz+jdl73i4woYYJQS1nNfo16JtpKbz8Rr8mNL97A5Rr8jKrAQEggiF21WbnD1ZoG8dMkWlwy2ahoGUV1t6Y3hUkmbrNiQlx/1ngdrhDpJzCY/zc6UVgrOrtYYaaMq88ARRCqunoB/AxjE38SzpEzOFgisuV3thKNGyk5GmLTnQJeBy7wPFclQM8b49+kpOx7KgjE6LeE1pxqQMaxWa4ochpcO7QFQ3u/joDnIDoYmegsHEEHLX+P93BeDjLBnyCc9TSbpug5fXEtcV9N+feVywzYMJmvOTT0msfTpXThUOcgy3+8+CwhsjEySEerDjgDAK1iFj/i6KEa+3OmaBM9sOOcVoR9fNM30rdMDWgBBdMa2JnAdgqFGlrZmsqhcGrs3ciBmRb3ww1Koq1mm7FTV3+mTkuPOEMAQgHtRwbQwB8RpntmRslhhc6M1kVGph584B7m7g6Q5KxRBEFc63b+Tfl5WDtFAZxRipfm3VgPbqO8Iic0+HVDb5seZPJjP7piMU5gKZpmGOfTYwQ7FiWSMjoluruwIoB2RRaup1GZa1gL2q2u0dH1LLPM/CQWgJ8A+Q9ESR7CZ4BpRGIaGQRLx3CPukU0hWAP2d+b9s116ZyqYgYcP8xgeQKwfO22ylitbcVvmVHnO5lFK0faGCh0T5A8q6BsvWwdeUIDuOClxT7h2JM2TZA1O/Zmcz+ysP+/tzDytUWTqJsUKDnBfYgQGv3P58EYBWifeSZoTlJTnAwNCpWSPXV9dn1KBawdckG4VjiQGh2FzLol32Niev6N09Da4fgIEMtHdnevuvcW3pN6zlnRQ2axr0TE56svzlwwlDbbPxYBk0uhzFlTyxb0STetXuC/vqA7f47s9P/M7VtXzVX3Cgr70170XakuHntwg89fs4pqaeNv6qxka2zOZ3O/BbOoanb3xjPHn6hoFFoowaf/BTUXfEIV3P81anZ4GAe92LY2EcgGnbuNrZwvUPEXeUvrCC8jnxd0xAyik9xqiVC8/nBulXp3lh9kOWFH8OwY7j69UltjsD3ur68eQOWu8AG3QzUGAnt5ZOBTEwhVaGD79smV3cJ0sdzHLrqgo0dAcRU/FSU6AXmGgHkzbZizozQvJVG7iQT14dqSMVatLG61rS0Qt6hfl/p739TBwPQ+7vtJ/XOZRdOtwdN5uSq3IU+KYbsmVA4LXJjKkWttOxeXx9lq3s5U9yNISY88xAKVA8enVLU/keUJJgiqIXYH8nIxJSRoSef5hYGM1kx+0JygCZk9oljnB/fU7lWsk6lRyhXwbThzwnwiP1fNTKksj4TcrDPIMWT29POwxJCpev77c1ySUTifDCnR1jAWOxE5J16NVr4ue2IHte9kj2EqHADOpmCLriYqrMsWkBTaEluQMExtGKbjpYWLRCg0uruD1t4bFWbfm5XkZA9EIRxfoBnj4ImoRkydIF1yyFxu9B4au66Cs7O/oQHyo8BBEtT0fLAaCINE0AAWU8qHJauSEpw4vDo/QTa9voF8XDrd0GfJBOmX3kOoiJvhlgs2O1WOMynGen8RgeZ9BhIpTT7RAEp070G+HYSB32SXsq9zfsojpiJsAtQyGkg+eYH6eo91btSLFw1DoKQqD0R1q2i3mWF5+CwxA6iKhurP0GLcvU3NW5pfMjgntHQve+CFyK73lLMCRo5B87nyFmwi9G1bwg6d8VxS5bA5TCIyujd0M4X8n/dhLqsoC3BEdkbsLh0bKE2gYHZ4Ez9mqtVxvBPwjLFLAh8W3i0ORO4ReKnet+ULc94SOwYBBZJeGXMx6rDelleqr8ym/Ub14ALJQbo+DGQwOazcCJ9XCEn+5itPS7Va/yJ+k2Krv40AjQvHfeURDS7t4U4JKK6/RVS7ljVPFMXpV5X8tK3IR9W2NyqDm1nPHSHHdjW8UpVKxyTqgEnQjbpjDfBgdtoqVsy/Z5VI2kHgjIpra//vhfYKXLQPx3WdKglnOAPnaxet74zvEqlykyRhx60zIcjFKGX2NNiB/0esIDfEdzfi+hQ2PN1Nclt1rP7dhbUUNYdRy56PhBXasFTuXuW0PfT7v7RKPuzB3TmGSSD1vbwL/0J2/6oT9XPeoB42y4Vkc1btABAalDbtokbK7OCdFdPq8sN0EPrKXxFqs5VowTYmqAfHRjqu94TwS/JWOyMxyImCkTIotTr7Ojhz8WPpHaMi2L5VLU1+6WQ9YhnzFlCOTzy0qtoaLpR6LP0MpN3b4os8HkXJdAJZSGd7aMEN8xCB0QZb6RbaMGExEnCfmWYYiKr7metVLSDecnPoI6gGghNtm0IVFMlE8/3HxPSmgJoyQn6CxsPbgf9R9AGpATWnQG2K60xVmJSCRZJvRCsDPR5qy6unNPQN3eBXpzVQI7MupWjZzBRttEFuUe9AbKg1IfRjikPupboqvd4tWmmB+eBtLAOplwXXWYJrX1vS1Q1pRRUwyCILKpGNf1G1j2BP8UqXpHytMUF31Khe0FEgqUhhA+92uOP3tx+8K9NmM3olRc5u3X1W2oS7TmSgiI9SoNju/kzumRkxB8EU4gfQXqUgeEFTFMebV31K5/O+JYCgti3yCBU0IMBnXJuPQsEl2cnkCSJUJZU2pthWDk5CfyIjd15XdyGq77VoNaQBPvrFU0qz0iwM5PGIvoUjqKGpW+qGcUzm5llRco2uwO2hItHB66gB3hRVWnSkBtonk42ajos48pqe/yhBhiFEbnxp1+gr8rReDBXiwObM3TgQyrjcrEyp5ErLItktvn0nUyEijcPNxUE+NliC1Ibc6FoXW6dJD4MizkZq3txfY1pGx5KPJ0VvwjlaxbJO7OwIo7/9juJCyGJInfy4KOPoKgFN+1qDSNFW4P9W9M8MBItjP2sU9uCyX2f7eqa2iLBQjViBaeIHA6lw5M0KFMWmMIn8oeZ9ZNDCJR9RM2fU34/rYAJ7sEzrYWIuFrZUgpHwtcIeArYADSprjxAPX7AyQZn3RtZBNjncT1VM1c9fdsgNnVFsJPghi9huU+4yWNrdJE/E09rH5qKJIFk5J53aaeEcXceoDrQg7ZWsp3qQ7/EqNjwHhqyPKTUxO8vzabUODR6lWp2zcpMoPz4AlAnEhYgHGR8/EDXD4GAJ50W+GKBM3awcNUf9H+nXCcJA7y63499xbbsm+amEMJ8gCmPEWWcEWHz7LoC9KI09qL4UJmvph8kJoBFpYCONUegkHnFvFXxE/pQAGtNx7UnMVVjdbxf0Fj7koGcf1wlPll0niqUPcOnkIjcVOcwTC2uvHjJeJ5mmnKDCU63UxJsrRKgwVC3OyZS30+Et+XSQ3LFxbwrag2GbOhRInI4/JrMA/ikvhVqmeXir3zCoSRO/RGmjbcqIWry7+4oiulGSvzfUtMZHWY0tycyjHffCD1oCxMj5j/7ZG67Omd8HK4pglNkF3jLB/bodjeeMwEOutIsO+k1bl0LqQqz4dZQ73XFwadCA73UdVsu2PiCdNsqyLoS3E2bkJRQjAdg48V2npQdgBwnQrs3ovDqwzzcOsT2mV0lL43u3JyfHC6JJhyHzk+6QpVinIQVeRWQ1N0mKZ1ZeF4UF/TH9xjbgAUDOSllUNm2Hxq3kvs7E7AqVebz2nlzY/QaPN8HJ1Iyhmfh/zmhYyj97xE1/AH4w4ApcTtJ333nP9mLH53gJcWyJBvLPSXKiIGaPETD6PNEhjYhVznQBnAGQ488bMz9jD6rgWmTPB6D5xSyElHr9b5A4Eo+Hsts9ExbPNuLKeg7Ib9l/2qn3myWlcJvTEnCF4eSHC1YJucD+wCOOK9lqPXc1xVu0ozo85ns44emeZecw2+HdL0mqIOBNtQ+2f66hx+VsvythDYc5jVHe5tx49OIZrMEQ89gfZ6KD8e3VVguicq1RweLu9GIR7pKTCQi0CJvnJSIN8uN9D02nxeFRwmMD2x3qZdbdvpmb1MNkWpLTDhdP/SHbRcnnGTaw0RsuXzvkl3XKJ7HnoqSeqdtd2HDKHplABZkVAzDfMAY1HssMwBHv0dh7+s6A+I+4wd3PeANk9UXmJ4LeFooAlotU6fWXR7nEYN45hdFXOYFaBMGqQB/gTTZ4wugAZDyf5hDGY1WJ0lcj3d4YJKbDEx3OFjxzDwWi2zluqaEHgnnvg9aapwJRtKyS49a3elEZj0THc5pq6HeVEMqiebkpUMyOYlUBAfya5cmHSk/Mth0Qm+jECoqSk610lQX3Yg411iB6kl+5hWVFDDagq3CRtyRb6cSyv+1E3UfyNtnIsWxfF8SW5+qFg+IXlP8hYS9XRPpMFe1okXYokJWA8P0dot4alsmzy/HP5hgPYRG0PrBzomPF1TefzWTu9Jgq//HIS+CSkqGWsLt98e4qNO1LKZRSGGAYgvtsCEQL89gigg2EkfxD38ydVpkcSDCvP9gYS1RaREk8rS1tRPpoJZBQnl0/JsEjKSkr+HNHVJo0S3wy0iIaJ0K07VVf+4Wt9nqM70zBHprNgBWcQ054mXFVNLqJVG02hjHSNHNrcCG8Ir3mUeR+9AeyXNvO5lpCilxQnr2GMBmiGc+7dxntWy9w8GSW1dmPUqYfBH0el13GuujBbYeDwcvtb8Tj+JsNiEpZDMAkjrCfk9tLpCgI+rscvD8SGK/bqzvi2sN6X/MSmihl+FT4uL62drF6s6UgII3LfkDeZZNDutk3qRGQa79BXyk9wHgCKMm4laUJzuMYxncz2E/WEmZ9pJONMi4l2bLmybNV3YaKsgIa5SG+pYu/mov8HAVRbb8ieA0GW6jHNq68VDGqmtyY9/Dqy391lNM4wNKsSoW658unXigPWGha+qI2YJgbNqGBmF9Y0cm3vrPfOBRgd7HzRKlRYXB/5awx3MD66BHqOGgib8T+bTqzypJCL3ICzJ0F0L87moTfE483pNL3HLOz1Vyf19mbCrvcMkmoGV79ZTR6gDsGh+rYxFw9GHpu+yi2N/ygXfVpCsK5FIXDAtaYsvu01QRjz5ZrZLZh6Wmgyfd0cx5SIIrdbkj9af5/TCTiTbTyiM4Yp+3z427p+t7/sUOahOqpMjeaiquJU1JyOdWF8skuBrrLSP6CfXACci3Nd2s/xxt4Se9CW4raGWSftQ33S/zcWrw/ZKGeOlKske9b1mQR2q4tZ0g9EV3Nj5YH4p1nd+F1LlihptQa0DIpUOn4lK4SPgWiqWseiHbdn7D6i47MK9SrywObGQbvCmoRByX2Ku/w9yEfsfPeDGORTrXqOoIXNC8g+hiU8hs/Y1JaqgFEHbGvs+n8KmL4pYP/SMrAeX3IaWxavCu1Kwis7if75RnSYr9JXlB8Ge2gEGVJG+zV7kKIJRTwdJZSSjTumAhFHh3iGea53sl6fgEL8jP5mLffAM/FNAY9suoj6WVVst5f7YKJ7z6Tnp1uXiKsvf332slhUvgOhyPaHq/vyErfipHj15EYbXK3s+G89C1VmH3PSTXKXRDex/ZVATcOuqvQdBZRQoSTtwL+xBXwQPVtUbst3N8pgV5BGihepA2+Ir5X1/n7XND76NOyd12VMMtOGrPeE0do+lDcat/JlxhWYSFL0pjH1YwxPy7bDD0SVZJEjy6CyUHzEU72gNhIShoT8moSFWK3fYjC/mATYzgzK6syMZLlBZ/KINzb5xnNnFoNdp5e12ZS5iQsEwEkcX+uF/dEGpKPk3gMrOCh2ap7a5plXo6VTbJPYc5LJYo26Mr3i53SwMbnqnfvIUmfKUxRmGLqhOHrsAGaVsEToY6FcvY2pAFU4VBqN35Bv56/lbbC6cmcE3NPB24CKN+0LQhxulrP4AsFABZw1Tj8jrV9hrVMJ64r3xJXov0RDmsBoGZTnzOfF+cCL3NyFPpFWtn/ShN06u1fspf76F0oy54gY8uUCG4uqGV8dQyG2LJ9ib2B1Pyrt9LIiazKqm6xOH5VVdKKZRVulY+4AVnqZygejOoAr7V9i+RY/ya1SE94IZzIFnNwQqJHsReMl7zHvVdtF+3cOxOOXczxSDNBhTkvr55ADrdxYATdOUZnxicgw1FyfoYFY7Sjz+JTgH/xGVDUQZjSGqYCAHuWy9prcHBWqMI4ymxbpmN0B7bUyT8Yno9d22L2DeQzHAulSPRBzn1CHUIzCP25jPywnzur1M+Nt5fmwwnUksYFyAaM7+Il0Er25uQwAm3dtheskjlzzWGoh+NBx5a7w1Nctcfqx8ofi5QDrVI/evLl0Wmtr3yeagW5ZcufuJE+DMniAHhwPeCaGKxVjQMQdPqiRQgc2zqYL3q6X8/cXLbEj06hIkWqmVkGxy4aPJjl/QUxDAkIf7GkEPmVkd9jG6lSFxodh1mWRqcbobueWdbxUtTnD0anfj4VswX1YEEg9NXcuVG+sgVmbz6SHbhgdyB5t2eD34IngqzdmygVuORd4rrkcOACNQcPEJSHIMv1Y2vS/xkRhlOuB3TEzbPBv1NC/cdX4bMA9w9y88QauYx6ZFbfA2ni4FUxxMGVYSDmBygJagZEHr9RQQEfPPrx6lMTk5uN98NreKJ1gy2krvmst7+LTWa/Ve1G+ZqFiGBTrTDZ861d6qv7PAGFmPrN0P5NF2mJK/Zy7WsyI2IC6QF/MIj6r4kn7toi0i2YdqNWYHkdEZypcsyp6JHSkCj/CR5nORGFumkiZqopbS5TX226If9F4prJXtP8dwIWt/EOYENqY/v9FR2mWlgwvLd+iYcS37Y66HHP4SOYVg2oD9KmTy42vl1RhmEWmAhGzKDY3W5ozGiA0v5w30BfOirpDq+5IiZi2cUIA0RAdGQKhi8WXwp9BPCK0xC0utgMIqyCmxTdqyyDTE73QZRkKA20oyt1XIZ0423n8jpQMzK2czli8pL9Nlqf6w5ZsTsZlyQrTi4J40wM/g1bkysnax30TMbARUl3ctRU4Xt/tviXXz/ISBpNqBS2M4LyuAys4rQpofEDtRtwDCKVCBXLFWoPKKpY8WXj1GI10bMWX5iUOoRhy7bsVTDb5pwkxMi+XhVrAu3h/xTNvQhcf30RYGhP2qcA5DfpnZbAr66BsIUJ216QXgfB5VzCQbBx/MrWCMwMNfVSWKsJzMms5aEWl4nUi3r1E3BYHECAoegXNeNKjz8p9BRmilyUBWYnhgYTZeIpOSeFByhNhnfVa05EYULz1S/ybk2YpOq/kmnIKM1ZMRBvR6CCABKwIKP6H0VmQ7RjLFLMj2FEy0UI5ywr5UtWDWlpIbVar1s0d5o6LJUQzEr3ir6NM18/He5xaD7cW/7szKl6uacA6UnUPCNz5zQQply7XUv90CUVC5GOINs78SqkPcpYwL1HrsfuqoNV4P19dXVg1vW0YUGL50qWNsxaLKAz6JczZJNKXNdfhiM+F54W/YeK8IL4b2XzuSlTAkfJsZHrnYojHjS70NQ5pufPPFNfOGDWcwLO4j6T8wLlK/vMykyRfhx+lczHRFPv/+PxgH9x1BKdEf98OrcH9BRyvWWUIruK2LR3NPAhhgZY+lzZq2E7nZMVeGcVFJZ3xBTeu9NXi85bwhx3zkV4YOHPGLhfo61LaG7Vdb6zfDAAfkwry0jN97D/xpPDvC4T/r01E+fknm1rMgpatrdXEjN3Rm2Lmay4gvBh1gwz55HZd8q8ifAq7H7I2lCbJfEFcBykoyrsNBi6YMCUy8zpeG1NVQ1JPwcypWhIak73Ig51N1UKNSOLBQDpAExR44AmQSoHHlNo9ikzLP58MJZcgLgPNgWH0uJmNLESaIf+14XUWjpjFq+ljQFWkjzy5p75zvPqVcwNdRZF8jxbM3fWJKZWp1cLA5NpKUrkzDfSoQDAjWqx9LdnyDHRp3EZ0IqH0EMXcwi7ZM+5urXah662iNtBhnfMjzGH3wuHIiYuau4yusxvAvESoAKZjR9iHz5ZyJXidK0l6wE2VKm7aZw3iH4rVO5Nww674pgBEJ/rtuk0rZgqOsl8aozj0QJzDoePUdCFlhyXNaWJ/NtaXDsq+1d5e5AwM4lhFJS9TfADQGeObjKBo2mfdGl92BOceFc5tUMI/3nSfSvoWJ8LDEUjS+/tiwwkaltkiNtxyc6SRpmYWtmxO1j+8ihU7UL+ESB+UTp6qn2YBciIO/2QckEe2lIRwZyUStS3KZ/vbmFjK3Geab3Xmn0yzdl4XVFRZZguLi+sKhDl96zmSm42gfat+HDYgSm86wWqUzKHBooYndKrIpZnmISKNdmcQOrh2jVsUxjg+V2wHHZvil0/qdSBFMFI05dvziGq4fFBLq56WG8q/gIiMKpyQPBG1CkQtDHuhMalkA65mA16GyYEHslgmQXUphxLrH5WDX3KZXR02ey9MLzyFu6BFVFBKApMd9Oye/K+xARfs52eSUQR9bOUytPnHYfzEwKpfgP2zE3v1V7KfzJadVuacRW8EvKEIwPUWobVXLnkQrkRrk0VRnHtytsUHHAtxZCpiS2olFXg3cqJUwtLfrm4FlzHQ1to6wJOOLm4RmNXIlZKURWIde2yoAVPn2YAEypr87d26oIKtcx3+ppUfO8f93AZJfCZarhd2OIR+okGejQhMMgIvvobYyzP8eKoFw2Enq0lH7fgFt559zmiXXIpo+R2KZit+kCxWpQKVJTvr1XFu+1yhYZc4T58D3HqVqqcfJH8aBZ3i5IsBXruiXx0DD86BSeVsGCBvQ7lVVOK3m4kqlt1OETm+SEewmlyS2INADOCP4OEMBM8OIn5ZTc0ExWDSr0fb/4059SqLWXJu4UeXhrn9URVXOoEvyNocgNC6v0Tyw/UHiMmEt6AInZt2UjRi3FACiY39mMlp0m7xV4tbdlDjlZt9TVzIfS0yJLgFXkbO8dj/iN3Mk7GQ9MwcQlI857LZMo9LnleWp1vQ3gJ9XZh5SXaIHKP2YreazJjL7ADIF0vIc6pi9rsV9Q/nA0RVM6JXTULgMlzo+IVV5G2Nyw28pNW6Xb98UnVaEp2u/UWb1W1EeGvVR6elFLdhmfBGTcX8VG+r8djJOIyrVzNgQNq8jvSIbSJ2dbZc1NaW7oZeBhlTYJ8YqLylJqHbCDDDE68g7KVRow2GkmHrHJwzSobF2Mp5TUyUATSP4p+4oNYg0/RV2e2TJr18DeIJRr/K4hq7cfgMIVAu7UYx6MH9+2FAIMc7t/ogfix2Il2yWCxEl92xI/zTxrDylus1vnfRprQrvHUbVw3vTY//i9yc8I4IrSCi7D1eN/FMB5yUqs/LckGTmUbxYs5IxtNY5fUNusvITssBOEbE0wraweYK9bEWHGuhgyqYbmEiB7qFUGTj2GRGIHz2WOr9Z7Wo1TTe0A0vvCAD09mswab1EXlCLrBFdMuc4Q8jtpcDaZ+9+lOz6QoyUGxllCYFUolfZnM05aNYauOMlgCGbC7mvZon74z1hx6+T0hE5xihVVnV6VbcQ9iQ9mdVwky4vzptpRGCuZCxJlWve3lyz+3onJpmIqO3DUJTyMkztOSyN8/ajdityjOWVN7Bbw+RfDG4RAf0JXfCLeMxOxGAryq8qz6l4x8Sk0RHmaNAyiaZOdsukxGdoaz2jagkLgaUeL1e4+tv1sRIAXNRvu4dFXiUHzYO4hzCmuXoC2cTsVirQrCxB/Yb7BNSsu0YXezcDKXmQPYQo0WGphVvnVbyZjIJSrxSPmilVWVXU7oymbNpi/BcjOOvMTockWa6P45khzCffEapN8YsClHREz0mjtCh17lpk4N38sZ2TvU1GaK+e3MicOdd0uOBki72+iFL6eUI0LCuYxtpG7Zq+FLfWMqg1pbViLn9n6SnhQ1hTJIFlexQPFoOds6LqlNZedTTZZKYz0/IQiZmBoSf4W/kuITHcaMGaSvhiB2NE+ZE6velu/Kqts69F5XY20aSeu3auvqZjjbP/DbEKWSw2bHK8pGETgpRxId5Fns9USd0Kp8GTanbyuYh/78ObF4XI2loo4aMEr2q1Pmm2ySJeDBWDEjiNTlLNRXeFuH0tyrd6SIQFxIRJyGt+Jp9UJhxS8uG8vS4O+6UIh8GnETESDWyoj6tE5lUlDaPcNDAwWONvm826VyZ4V2ZUq5bf5E2bZJoaibVA8+1YlbcZUBoYBeeIPiVPfr4nSqjIXsgTcbgHtZWYDY2ghWIG/n0ALQB05Se62esaXh526exYTYGax0yb2mu+nTRgNkVGWvhBMMRfC5EHXi81fHIhc8dQnRK4TGd0XSZOYvwNOOEdoYV+/Dk43qnyoqLuyyuD6zfVxVd2KZB1yulCuCKTP9/bIXhtOnikPHLqcEKe/aakdxqqyMsD9DyZHQBeZzVVPpHTgxy98s3UQPvOJNOV9kns9PA/8GyJr/Zdxrup3LHLvJsnXHkJmLYjmjVNCpEliXCJpiYd2h/8pxwY7Gdc/WAbAtsAeQ1qNrydvnKMLpn5v+b+bWNMeoUYuCtmhylqcs5duJQ1C+M6s7s+p0FoLz/XT/XAzR8o1M6OVqXjz5ZPI2BiElFBkZdz+G736AXANrRHDOCd5Bm7+dHBG3ZTOXn7YVW1UU/ANvedH0ZtCcFQb73qIF/6xrJPAowJKCMhhw4fboFDXjdDxSe7TRCC8eQTDpGnvCcTA045475+7al12X28miJ1P9zj2EXZMUg96E3TwAZ5Wql+GkeyzmypffB9xLeIpBdBXncbmPDwv+nO6Hlz0pG2/P9PluRqwckBvq3L2woDuQtItbHOrmXkfj/OdKeCrK006a9+i0lkyfbEmvb44tlKfzaiAGGbf/N8t3GBskAKac/Q4twIeFKy26lnRJup18UQ98GyqFFxJRmRMjneROj6YiAXYKfXMvuioHbM1xdfOTYGC3VD/ecHMdAZth068uUo5aiZY+Z9MiyrKSxeJzCXv2Nd/+14SmgawdelFvgwosuYYCzktxVMRRBVFdLp+8Cfe/unYhV0oPQzlaSzlgVxaiikRqwWraxdEuwKXDx0tzHRyAi54kYgTlESSVdTcGcCz/kNe2DAuO/+Uthe+SZEaFkzoVHG8yQHj0DgIMjgwWqfkdswGKe63MpArBeN2lH0Tgcv29DVMaohsf5cDR+9tyrZa/qQXwZUmqQq0EPHdVzNa0WOUYEEfrkxgzgev/3T8oxmm/LvLO1+/etUK58yS6subMjHxvw+K352R+jP290OBQfCpxQzQ75xLTUFwi2AxH58pPoy5I4e4QvWxqCIVFXylOdz7tQqfb6q4G4zjgc4me02y0PMCMRYcsyFIChLH3/KmzbdnavHhljGTQS3T6kY3j/BB57BobIOeNuQ9wmg6vEzJrnwjlQHFxjvR9w5wwGUm4/RPWnq6j6OrruzC3qhT4/xzQHVvr2Je9s3VPoiC9JCf3JeX4A/t5j/ySNtaoZ1Mr1w9BtV67u/oM5HdsthozrHQVa4DUqEMF1wyno9XeT9es6eUfLVBmWdIKUi/s3hTutBi1Uqv9qqmZedFHVM7dlDNTgTZMoK44kYfcFV2G+gVerILHl9wVoBmc2WED97jf3GSREy99oymfVr1Cg88Mnv9+9T4JwKCyOIBxxsHJ4JMiMtzfJK1DzVklS+otK/Wcd/qgsLbPyeWEgI0p+3i83Gc10t9SnD8CTOwKGyzGCl4eY7G85Sw9YHCJc6NEPvHYZ24Eb/Jahln4NKEg0I+ZRL11P7KvKLkas0flz/u2Gfio+DKfmUrWy5TeAVpDZ2meiW3+WOWUoJwCHKqG/CsQbH14e+mXvUNTU3p1EsiLA4n0iSgez5J+PsobCb5xy9CRSpzmNc20zZU76YKIJ0n52SbToh97fvoFUKEYiUISePRdz0x+Eh2DHfyEmShfgGbliSE0IChg1L5nha30zIyYbD6c/0Z8MXFUEgjh7+FulEhtMUNKkEWqvnHmw6JgjYkcU8VMQGmMS7agWnRy5DvVyBS/Io3zNTsCFfK5zuXlaocDFf+0Wq8iqdwuGS1GLrFXeYT+vZ1XQRCJHM7PQJYSyYZ5/0iUudN4ZhilvhAaqyBo2VcaslRWIaT+GkNBvhHab8r/dwTb3Ua75VEjI1fQH8dLBx8+5aGWx3roU17khgIrl7X8ho+Qd83sjTQ5VQ9TVSh0D3OmxeWn3Qjm9BZ9z+HxAJBF5F1OY5HQkRC6hlIpcShpvzTUcAsfrpm/Xtb8aobZkQMuHw3V4AARZU1tDUs1lfPPcM9r/8oU/d85EGgN4He76BxEfFJ88ZAUhWqjkd8zA84mw0mBofWPqQKFFkzdxpdbS/KVXxHYwtNtjIjrJ+SfyVaD9hIzPhjbj8NZBXbJxcRFCGJfGsI09JvL2DL5Mfc8f/ZGxXwSoSGc2UZ6sBYXmDvcMQuuAH//cDOsHHcTaQgcmCmnWCx6DWLUgBEME/6YkNJRQSm4xcPUVCtfhYZ9LZ6R0BFMxkIj52hg3nFJ1QR/L41p1TufLCe/s5iWDQjWaSla0swZn90f1hY7/Ny/l65gUgOZHW5mFd7a0Zikl5g41C96X2ksYr2dt041PWet2vkYXIfLv82F7dBiSdC7nN9Kpe/Aw4ipmy+mpng0XPiagzSOahUGAoiDTpc8X+uL0ev6X2d6meF4gWiT4EYnW9O8f/fhJGSGzFDIGxPjgPUiy3Ig5s4gInN281S/NAlZsRwnciCSA9qewBnoYrvVezW4ZLhxsxCV4q7DNfedfTMTLHXwmKxhOCoDZtsVuNi3UF2AeWZCmCIoPK0ao5/6iD1GxZbsAV9TwZQuSFmrMOroHWdbngwRQU6rzXu6aJ1zM00+2PXc/1uR9Gpn00sYz5Zq3T8kgm0DXH4QfKM87J1U+ETuOen1upGUW1zZNddm9F8rBHgMKoc0KiJYtRhNXOR/sJQUiaJGYSQUjv9uugW8TtaJp/GKKz8n57ECgDpncl+8AemFTBDZ7Ytgfdnl3gU8XfKgxMRi5t8E7c39fnML9W3vnSp+DSStZ3BuoUOPBtqALQJF2VKbL18oe0ub9WKOc1FuGvDzarmv/9T8mwIIEQyUpSTrmOO/cw1slb2ShAl5Csx9tOdHbdP+Onap+Ri/JCaXGNqEfjqK8xayk1/DCz7UkKUjfAtRC0mjcU7sz+kS4mI1R1+6z++7HwyloT4Nda4kX2bGc8uXO/f7Giw1dUxhNZHvBm429jolbO0To7ILUcgHoYAVxTA5FV5msUijDJ0XwraaARc6fcsqsqgr9Qtfu+gwrp87w23rSUFIXqCDcdQ60SLahpZlwYPEuargSkv6Z6OdDw/Q5qH1x13qxt8GqEoiTJUYokmtuOAZJdHHlDfwrOMPs4jFCA7x0gOItdFFGb0/qfG0GzvCsZY2HW6mBa51aq2j63jzSloE1lOJqKBAxcaWfiZPGxL1CHjGgktbU3qL1BITv/r7jIzTYXlPH7JcanqbBCVmGoC7cpB1OF315GISavtj7xyF76mtxcf2wqkqr0k8aBkuUYUXcKG4a3Fg80bYtSYjS/IDBt0PtsvmJYbANFB8g9ouZC6rbhgqo3mw8A5HxlAcMsn+Cc/Dm7p1gNvdiflgyGnxqHCollaHyH7o5N39hg4A44dmkcK7uaBieZrpPgZOTIooF7/HMinBQjqOPFc41vtZ4v9weDtCEKMoJe9e2Fj5460i0imMmLuR3az+cMuS1OnNrOimTI1QhZpsVCYrq6gd16fUntLEm2GEQVgAJByy1EbkWKC+pSOUi4hrLgsfhjko0oWV8zLlCb0TQKX/+WVvYO9t2H21cu9saFnLm62LViWzWNCZuGpzUGAO1sOH6OZsKZnXZJypkCARK3hLvJ7UuX0Dl5chPcw9BWcJvmH2nYgr13cSa+G1ivvr3kCM5LnQ8EvshGjDWQl6cY0czKwhBNf9Fc6t3I7iobMYCV0hMxSYjK6kuLYpmN01hrJjTJyLEc3jBD5jNWowcXIDd/Bc4c9E2zm0eBo80Xnl3/jGiQ8puH4V3XsFs/OqIhx1SihzPZH+xZrTXxRP7+gQk5qdQJwVbaql/BtFBcfZd7/uX9+I6aWRqj93YMiX0ilA2vd8Ujqbrh87O4hBUwVcdzFD4jlUtuuP5agLVKi4U9sKVyM5+CRdK81F20X9duKBPDuzS5bTlVcu1OTHU9NyMEc5205cy4HEhR2XkErZpowgZUNgcGI2lIwZMlC157smw9tzuL0YIKoFLUVaXDgRe3yIVvP+yivjxrucz1m0IgpS04bfCBt8LVoRd0uI+a49bFEHdhoUtbzDVSX7JW9VXYWpuXAzd1icrkdAmho/0Op888iJXQxeEYuYu8shjAzdwnE9GmdBPIUvVYubI51TgUFdXjQFUZrXzdUFu8uGtzouOWIGbA2+b8ULd8w+WlPuhleyPD0q4UvKHWQ6xIt91anlSfPytOSr6020+4VYbKN7nOXQDGODawiDz4AnDl9ELaYmT9NUVrBdilZkeNfVA3zM0J88LEnPg4x1Yg/m+qSoQf5g02G0wcdarHdOMPFnEqOPeGhCMUC9QgohwJlRQbsmBx29noCF2/jPTgPv5T+UgC3eWMzM8xJP7Q2GixlZg7jwCOS6ouVZoTCPUZ4wNFLd+mHByBR6rb993rh4EXAPYbLIo9woOIO+Sq6ug0dbPi/u/jrIjYxfURvu5U7OiQFuSMm25RciwJtB9c8kiJAEaRgUmjOJdbO4aaTCawC0IYFUw9r437v3jqpehrK1JOjWiw9CCyGHtf5l9k1G2dec3dJ8Qw6teiBg9IjnTgyVKn6P1ldhGpNYl9Ig5VuPtHJKb4Be7uJ4YYGFtah/Q/WdRkYEcLhrIccRw0azB3L1JzAe5eIW9qsnJE6CBxZRip1Eta6wmcopKftlycMjO2RNwHC/6/Bknjb+kPN4mtWc8Z+mTYJ9097ZUR2VIcMPprVnDnw4+jq8VUaqVyM6sSnR1jQRShaFWk5jQ9prYB7ppGNkdAP1fHpU3djotJmG3TAPrR/sVdQRykIfV8JzgV34B3nGjd/q6rl4NBo1X1nibkfwMfgFtx1oBMAA6l7dhUcNQXsZLodIigC+xONS4HCKJzeAnX8aAY2gbQTT1/FbyR/AYhOlHlqSjZZQCY3317+ceLeGkxzUYr4s/gHQIA4uI0md7bzHSjOisD7h4LPH+6hCwiHd8zsgRifodEdMT2z+Ix6MrNjjsujwECSaTTcst+3Szo+wQvrfQH1cDMlwPf25pkFa3sutiyuAEuTEo4NL08eATsm9KnM1Oqtr3oIwLnrwrqVVwmrqHPnkyBQLVNpY284LkAdwkICtqqhQkIdIu8MosJbmZyAY3OBmz4s7v4Spqj38760UkPsszhAmfAMEyAwJ/qQkRHJRC0JLLX+MwTA4h+XbNUsD3I8XZPGEReDmizF9zgU+lfOzzqLPBlo3ifXCClAGAsqNXXu/osxzvoQ0DeNeb7Dz6jipM2x+MlXtmHtRZk2DcBRoWVf65dxtW0abxchm0yzpW26h30pgLuZsTz6Ks/lLwhF8n2OhS5NoTXVxjgU4p5OkkNbx+tzS6f4Shv/AFDT/mJ6+x77WwP5Ea//O5nD79bhgSMAPP9KxicsAwjXOwVhECTt3eq3lSCRzQbmaiSNk83i7gl0oU3+qCodIpzmpHB3vpCDHcwWoHFi4vHkp7H5LCuEyb6d+2nVu0R5kW1VZ7BN7XDXy42uUK894L2X5ZmeJZ7hjwntdkxlfAKHncywnvxM4rn2ZqHtC75SeZnYKnsuJ1khXlf579qWXObyJMbbkGWLt1aPktC5mKYvwl7fxvR3IM+hi6mzXbNCw4kbJFUGGY6afL1JN/xdwcBnAjbFVxRSzhrJeFilE35gSWScYug/2KcA66ZgCMRbanhoTbaFy1w/1gIxtJ5F5YJXO3QL/fmSIGhvWI57DMsY8JaZPT37VztmSHEcX3VzViDoPt5NK+hMg3P32NcNFx3S+apfhESA21L2ppHSZPIMEVACI9Mo4vs9lBWxS5KrUgv5NqNS+jBzbbIhb4wpM8uK2/wu9h+SEMaoKXf5S76/tizhItkQGG54bQNgdj3b99nW7bR+ut0zMqPBSWcMbvTgFBqOzKHidmFmc8AcOHzLADn5srEBTroFUnN13WIspYEVq0FjBGv9RvMgQsR+8p4a8kSlGN1Sgbgx2/LcC4ikFUkb9pggvlGzVACro9oRp+HEjHcd/0Sw53OmJFWt4hs1FS660LbC1tJpOCAtLDpYpndLN0cLzzNQ9kaORwTIYb+Tl3Gqv0NJRKZSym10obyNF9VWYhQzFc0GSurhNe7Mzu79/V3tQUSo/LDTSSwQYW5nROPhU4WNoH3jkokvvapozdfPHomZox7VHZv5hyNl0ETu+P5NCNwIRyB9VYgSF2Ky0dUcbhxZ+YzJ1SbBKFdSOhwJZ8OwGjFt5jtrLI4cSrgxJj1cJw9SBgyGnMsZlf5BJPIWi1qmynrxjk3PNgebY75GUoT1AcUDrr5jE+gWElKfmS7qP1T+KLFQDM8Pq1yPnliHmXFvaemWeEJvw3vZ1ewKxfaJWBAXxeBXA3lpkdh1QnTQbDMvDiuWiiTzPpAwVfjev56VlULjwT9lBI/pKBsPIFnQNMB7keZF/bfCulw1nERjK6Mt97SCZEQtw4KsgfeHkZAl9il9rrEbMEJ1bYWOf01zDX2prxjonjUEVRg9hW1qbbNjBE8mX6+3g2ym6spfeaby/N58XPOs5a0mkKr8FQUilquIZbmvi2ueNeFQ5plksaQyYWNxzd8SdKB9ZRINAJLEc6U0GSnAjqpIEkHASLxEVNPWjHDsYzKtyekyM+6BD5lHh/b55BzRPP2DOEUuDxj3Md8MgJOBdDLaQu/jgiimwsf9Z1AVImoODr+WGPqF/TtxXuxyY1Z93kBCgcotAdrFwCFR89PCxxLbAO4fnXNl94UnwYKZsFmRZv+Hy982pKEmMHwbXdMrnmRuHa4YK2rNh+TXn2q6xyrCvAijQx/VpXsPuAljyuCHvI3F8+mH50+DpsX+GdRkw6rRSqHw6USheoOAW6TtxOuMyqQwta7o11ezOHpuZkv4PAMZGnP2/XbuUdu11VGz5GWh/o+HJKldMiHXLIQUO2dhCYzOzKtG/xOIGvi0mg3uoUbkHBi7CG+qeMd1GC8zDQjZvOQhNf4dvtKyYQzMuz9TznlqZkSqAb1wpoTPUlJgaBt43mWDP6JaTWTGPs55w+rxnoHOBrKQIaDY7RLuZiq0IV3iuBBWsne9KWJkwkiilq6IV5hy++QFo84pI5NAPPJ3BGrHI3bTVgjG8l39F5mY7TxtqeMeVriDEiuY9qO0mIXJywnlO2pqD3P78y33jmrM0B4o1c69ZHku+iXvjHrmkyINU+F3ML5dlu1c8zA4/d50E2IBqT1nmf5KQyX3aQKmHTGDX7yp4O0z76LYIDklnm8QPP1yj7teffqTM3GXsp6kOmaUDjSkan/IboAYXU7BIfZ8zB/tdNwZLUSqGKHzFyB0zl9T/937EtfCfGSApDR+IVzpyXprGoGY3tTvLsS/dRhifDomH6c91Q3z2jM1jd9Z2ZHDqzZaVpco9DP4U5py6x6MdcadcVmeQA2PTw1sKDf574vTEIAWE9FVTq9iPO+ytjkrhZXrr4j+6GR0irUwhNioMhnrlA7Y1h6XSx4a4EMiO2NHTAznlANJIgLGXd9ve61BrGg5jy9OhYaQlT2K4XbJs35FQQTTrCR+gShpTa8D6WlT/Qz+9hXcHLOUUa1GnZpK1nas3+FnLxw+C3/jbXtVPNE0JGIYmNyL/hZNM/ZIz7jlmHb0ns6JjyNxo0bZp+N2KK8uBmGtHI1jPtqq2jwaTy6XybvSvScrFpN5BT9RHgrIkrYBqKUxAdCtvRuUfrcJyuwcbCV3S6exVcPUoWrvyalHDRcjFfU1kMcCktOUwDtkaf7dRv+ryoaSKprtbhVTJ65mBP0u5h9hxkmaVdJzePAFdeutFhyvi5144W5jpRBbTYdV0RnIwWJfHvhy8+Q4UriVaCOGq3f3hnMUVU1V7z9r6pIgRCsF10Tj3AAETbwEsqKvvzNmZBo2cJj3gZWbiBCvmNTpH2HVsoHzJqyboOS6Tsk5+lOb35XhhhMz+Aacw2ZETpHG3+N8dzf9EZnoCFPZ8M9mx/emoC8Wbd0oj+BN6h245vJw0JWqeEzdRCy9LsRFyWe3smliHaGhKtRZjYuHry7ESw87+Mc3u1gwfxWaTNpehUWe31yXKDbNeUTBqDIxqD130VbecU02XzGu9A7svLrYQUbp64rD/vFr0B+a0QswD9OSQdI/hPZG6mazo3R1JoC4eztVZC/5sDtDYhIXRWIUumlgjVrUxm0jxriY1tlEueRek7M0MLFZjCcmFxC2rq1e8j3wH2319geuZwwSyUCeBYCN0ergzi9xh8LB0aX1LyEaECOJYnkxLNFg7lll/Ifp70ZkBT+EOyXCviYly0XfBFdFXnslgLRoIkDs+7zSRPnNxk2TfwBImanGxFm2kiDKSNWSDDYP0l+9QYHT5dsqgg8zVd2X5bFmIliXUtKS+cijoGdf0qMZQ8mSlksh7Lr4DIOLIyoZ0BMtgF/5ky/S65YqpJQoEwq/H1rlbKcmTIES9K2UadA9PPrf5+b8JeiddVDytTUEPpGnaUMHTB0aqTkxm4tdfzRaDYCcJKtkprG4cW9pxI2H5FK1UZkQQIvlbo6n6ng7YwB5hBGYDJ1ZkL08dgfZQugyK3KBMou6wDsiV9gGKxGWiWx87XqJh37COP8WpvBQS4FlewVClC1jbuDIwDAYS2VAIi3WgdtN7bt5FsCFxxb/GY9dpcGAKooVavOD49XWWkRWm35z6VMZvWgZb5+u/Wogf8AdbNogh+JhoJKruEDRgFYHB8HQkGXRIn8wwc9hdhUvIs8u2EBJFkUj6xlUxGr/EILaKmeFRXxcrGec1dAAIWWMshx8/KC0uzU3Feqy3koauHIu1Yw111IGCa2/SXYObsUGvzuCcRdUKO6DlTICBnGWggbwvzTj1lTdMQAM7wrKdJWvNvVavC/BHVLPOu7P1pgiFaiKW9tAX+o7jFTJj0YUvA/D8EkADT8/a7ZbL1hhfqw4VS9nIDdUjveVrCEkNuo/k3TFCmYQGFRpxe9peildE6gLlA3ggqIYW6kzDEc3bUNIaqImdealsMUGb+yVlyp268hXAxwaMXLvR3z2El34VTw6xB+dYUicVcS3iR1dp8PGLyiW2felemNVA9ptRIweBuK2jMAzR/6OSnG2+thC/x94Y3+UkNmVQAQY3OURQIXlqIk+wzoMX9aLFYgSrkM9XjcvBlRpeFQNWoYvbBqlocG54MAInlI8QzAI7m33EAD4Qbpbool+kSRpc3TJB4nHg0fSkWTHIGXICQOCZiSoi/l/UhN/HdqatYloEQ9OQI7wDSTLyDDRdckwwr/HZQ745G/C8oidOYGb7w7CEzAMlpRYfIpycUEM+OO2x6br10+/Mu9TGEfsyFD5UOXVXeQgzQqadF3FIC8YB1EsT30bHEm8LtbQUoYzVDdPJZZ7w9//LslKaz7tslEgLQ54oBUA6Mey+391S9BWsuwXzF/xRri1Prtrt/q3IEkfxwsAy+G4LCgP4TrFoRS40ayuNASR250oGVq4r3Wv5iSBqk5Jd8p4KmTWvTarODyjaiwu3uJomDB9n7SN0U0Zk3AKv8kg4CFAHRxcBtCq7g1Xp91kVEdIB3kBGXJWkOoHC+wN3rgIRbV04u1ZaDGifAB4AzOt34zuzSzcOyN2h1pMsHrmsb+XuM5Av5zyWMgTMMb0/v4ooU1jp66qT/ccJqao/DLL+uZ2zj2zdR3GRtJrIpLIidyx6c3FsEKuoe9Da++oMHIQ4ZYgGGZShvMgWSs5+WCBALXOYoI48qrohwENdR4UAVaGcaJp7rGfrsJVTI/dJNAF2+a8JOUM8eQ+TyP5TMxaiHSoAkaK46a9HYlGWprpQGC2BWQ0ZMuEV+WS9eaakweRmIAaqRuk8gIpkTkqJWmgw57XW9wzD5Wz6h3OCMxDcM/E3ESmheWh7nT6AOSERd770aAA6AjfLYt4Emt4cIPopaOdaYR7nnPiQuQkXMJbrZeDRa/gpVSDJG2p2DmMl2G8uh/WeIwtCCwbZGDipDHNRWM0weUrl90XFyMkULe+Hw9E2oK8ghFVEIpHoTYLKWdmAi+fBWblGxDWwxoE2WG6BHicE2dVouo9w/c1zUeTKULEHn2TJFlW43ae8l273Am6aEul2GmKIBK3Lmc10ZCrAU0AkFXYj9J/HWfXTS1VovFHLxL32T7z42weAkrp/J1edmSFuqK9r3nCUnxLwuvNG025NugJG8/JCPKyH3EbfRzY9SUrD++G0a9S7Tk75Inw5OXVQsXjpi0gy9sHHtKBgf0OZudHJeECXhN7w+uOfSD8j0WJvqit+cHoOlbHYTAWSKpmBHu+3OrxRfNKBszfx/ONMkBfLjdTuSdFmMnMFuWdV7IwclzQiAzL39BN+h/k7rvBlta7lq/2Zzbtu4btsiGH9jBUmKvpv/wvrpXDXt3HGYJy3qMjeAS7nu8niDrWq3hO0tMeY0hJSV9gY54dGZODmRkGWyVovKAkXSttn26D0jcsJiVTVSIhMKXwW5tiDNR4+HDXTaTtO/n/rDAc+xvz99uGzCHMSvSnGWDArLsricUvSkavkzkUQkxIhCJsxY3Ayh8kx80XOelAASiw0h2AixkS5qd3sm1EzNtAZ6ukPDQk0r8TLMXGCw0pD7bBX/LV02ZupOBPfYgODxmZBg4f3o9TYtkw9DO6XrnY/0kc5LhypZ1wueSwVcWKWS63O686dpShlf3E/eKJ1dog5hWljrU73AtWBLZcavWmNb9RxuEBdprOD+tm3xMyRWwef/gJWXio2Rwa9E7+Rep3HhJJns8GaTrQGWLyvuw19QMcqCJ0KvmDvk4qxaG5aF8MayoDsjtdyTq5fwBs1F2x9TdU9YVR+PxvhqH3/o/uSgvFZKo4gcnCKx6/987sh76jQ/Oa0TYIIoe/vshC70wkt/lk9YUqUpl9yJeS9/ymcsqxMfasvxLnRJhO6RaPp+fnAU8B3kPrzNDuKFMBJAYLBHZGndsH9mSxHaDhC4MEdXpyG8ulV6uyUhr29soRTG4YbN8U9PgB67X4tsH0Kb8PpJ4o4uYaSC5qD9RXqu6Xa/LEoSup7hHKGOPZZTgZ/yJ7HojO+CDPvsVWLywnNRfsiMeSO1Fi66u5RJ1OUksk2o/PPSn2nQkd+fzar/MrQ5TmxeKBF4zUOHlYpSkmi6IieVSpP3PP6ias/OrGw4GqROd/60ZTGLogNpK0cXUTjBp8o9SEaaMExI2ydfkqjHWvhc3orFYv4lRFEJceUaNb/vdW/orxp111+61xuhhAiADsjR1EmhEgnb0sYba95EvVZQRIpsjWcGcYKMNbU7yhMT4093BK921a9ZET5K5WozoDCoqLLmB3bGyMt4wjZXZgPHm2FOluwAmyRyCilK6e0xFVr7FnNqLGhrnZ+YEnBM4jAauMMeSkY8IqKGzpiSUPoKt0TWKLkU+/PFJdXbohdxKWgwACs9UZYNgCipvHvV1WriF6y0j6KDRX/NQjOH9Yh4AfXI3ch94s+Yv0TSAdtm39wGsdRqjtTmP934qJTjwXjwQMPKTkR6cChEkZ2QR1FEhb+n98JwWbzu2pZOnNkNcCq3ip7sOJ/LEsMFUmMe4yzLCgMxpB+dqWPUhg6xwUs8zcpq3NrhWTE0HtgYZMMXMHatyZ2K8ynDJl7An+uBB8Pr1BmWqWJYoiogBf0hcasFb4jQISuWP7g6MDFIlKnrLW9kYvFY0ZgFJ+YAT6O1n3CXBa6UcHujBm3+cxo+c+UU+HBmIJr72rY1vCqihQyc6g6mpfVJJK13V1Pk3Ul2vUgHYbEQtwLAcC1Sq/mDX+4KPxGDoH76JX8G7/DI8SBngvciwdqQ8A1VTXdmNqPxJf/JXFMuZzJV6jkSW2KbGm+f5BzhAjNKOdqldU7Q/x3BP3hkF6Zr3rvHVkW/HVzI40p4QIQR3sKuGyAbZM9jkMBG1m+noPPs30+wYh+Toyj23zKb2n80eDuCw6KKLPs+NsFBe+9vkx2zCl9/X5CIM5LXaQWZbG83s+DJHMNzmRmHp7vb3OBp4r7b89O2WRMBlTFchmrCSDft2h4zXJihGhxTsbWWNyZa0+3zrtt3Kq35dZPMWQct+96FRdogSQl45pt9cG/4iKzYKMav1uoKOXYJwyjvr7Wk/6LHHVoEsgfLPYh7uXmEuSZErj2QP4ujTGx9DqCrzXQmlwVyirM9gY4x6/CH3iWaiU0EFy9adMU6UNUvZgcaI0tMNTOz7B0kvRJq7vZcB3I8tTXueN/s9TTEQ3nPNExKAbdrpHuo729/N+TP3Pat9NoMZlaDG0I5Hp4dDg8J1O2bqDS5AnGVKSVcIzn2M4gcqyjnifwvR1setKVKudqgwnZBw3hIP7R62o+Hhq754mNwg+bHzlKSrFyu1CM9WKhjp5AhXN29CpKvG3fW+VZW8TbNFyxHibtAx2NLaZEJsozY3mBdNU7zTQYYtmqFIJJQ0jACdW3+7oAoX6T5p9pfRYDiAeRipTDXZxFC1m2trg5Sq/wJCxiObufYUkmoht8f5gkWI0DbFXQxlylcwpCiS+HCnUHOcgsULb6VkMuQaZq/phgUcU4ZBaNONNeS/e/BpWbfPV4/MWzDDBegrc72V97sVjjhmaMOE9t20hF/uJDRIfNPkOfHI84VJvA5qDMFWQ3fS/Z/kH4eGZl8S2VoBXHc6rLNZXhjYZDW1ejkDC/TZu1FXApbXNb2zdbPMGZhLmPcis/QL51rKU7+86BFOOrcvb6qTQI16M7TABhfaICnLXgGXgB86qqgIbIxX0+gQq93wvqGh7v5yUlIXsSu2ivp2iCyAu7PIWNOJFsDjjjUQEHS8A0eOWiPDbSaMv5SlPxm9SpH6kpQW49iULjU/TeG/DFWbDweFQPvZZgj8segAdMhchMKPvS4pQxAtCbY2yx5a05s5TIvqNhisWSN2WWz0NdgE8CsecszlB93CZfsJu7P+w0WI8vq/UT26iJVmQlDfGNoIAsQDFj3sLoHVxiqye9kKL2kVdvGCpWpMrR7tkGtDzEzUxY5GWI3P//4c6OhJEmH8HIZfq97EPeyBIFqfx/MR/hr0uzXqQRiy7m9ngnAz/7JQBx6KPPeOMeP9V/DOLoHcowcWknUTIaePqTtoMynjgtyiirZ3T9iNBnHMFO/l/QbAXFzI51pEeBShoQPETfmS7yPgx0k2oodxYF43ZBwL45jzQO0ykaZZ4tfyjO6Gl5TwFMyou+E/pVdAHAfj3nJVP/rTL/trWbZhPhaGVVGtAmAT691qZikKxC0qF8+SVFhJ+QvN8UlTboYySJVKcwJr0UtVmQQXZBXXDw8Gd3y5OlYrHJSNh3PxiU6Iw+tSyNSgMOfigtkP3DgWjkAi+JV2R9mvq5Fop1QHuiKzRSxYG7fSBtt5oP0oUqURPaVeDKc31SWqf8IAUKaV9H7PZbuWabypOOHTWr+Hlj0h4p53cIRoeLNcNlIbGL/I0BbQshwpZTWFfkxpKe3vsH0/y1sjoZ1p3uMOg+GSGJg6/a4jPk2zWWKCVK045jhH0QcWjJrrOrnQYILtulZrE2NALpHniU5HREWy/0MZrGaGHguddQhamW3PoqwCLic2pTgcYcwJ/aJnXh6a4KTIz4bs+cHUEVo/deA5GRwurc0SjW3uA1GZXFp+wSIItFZP/RNOYOA+2hCv13KONIBXuEbC8LKf3i1ZfJtScbN6HpvcxZ2exc+D0vLqWYJ04sVoUYFW7wq/zF/HSo979xwwkc65Wx2Aw2kwt6Ebvj4g2NVFC5iB4v+wye5LympkMygZfR3gHpz3UPw4QrSYfqWRgg94QJZto9KMO9bmU+q//iQgYbtWb/7nwWOYSPJLkBdlXkraRbcwxKpVtIOFPY+4AiXCMrULVvv7R2MSJEYwrnWj1YD1n/t8lmP6SARjQ7Aob8smqp00Ceg12HvRYKJeReK12Xw4oz9Vztxx3y3ZX9X/IuYdE5eJw2jIUQYBpmuc4nRR+D+A7s6dwCLEL8I/NW3oqVnvE8eoDv4qFXn10IdKVtHHVPW31hZ2yMjP0AicOCk34J5NzH9uEt6w40LBHjhHWRkCHbGysEfayLSpvE5m0WsZmT25yUfDjOR2EmOHxVcq0SuAB6ZI1RmVel5vVuyLoUoUYkqQvmGAHDPRIsBZBl1C3thQ6/Eh/3V/bu/RJouHamm9NZW0KkocnWCl+19AKJQgB4/jBkOQNVkmgKF79h1KJeX42sFb/26L7Tt3Wu95WduRSWUoFRVRfCR77xsD8HQtoQSjYtSoDopp70/hJCDuPYFkxYzgJOKO8wrJ9oq2w1sdSQnJxXrM+6m/1510gHZmwXgT2etXTJIAt9uuu6lm8eSViQXHfgvH/3Ol1bGjncwROVZ0YyRa3iKCaNo0GrT3lrbMOT4vW5jacbIFX/KxMeOKEQkskzfE0Ssp7U1oo/GCzIYTwMrmfqFHg1m8/0WjthZ1RhjIIRfpn/zWIQu8IEaq5S4soZPtZpkrNWNXOpVOpk+TQZ9wcDoSt14pyq6r6Kfb+Vnzy/RN1gjzCNxyA++eIw6lt5854hOCYlsXl9t+juVthq6hS1nC7Y2uw5kf3R4IJoEnodnrGE8m/pb75x0p8WhDMUB94hBQghZfirP8bDSbhI7Lff+Zp7TNKgUfdSJEupuFfFNXL2IQJpIigxF8SOR3fig5mXv+vLHB6ljI0GSlwf07SYFLNs9MpMOd6Exnf7dlKCoZJ6AqEdV8QjEC1HaY4wvQoBdrnAvy+vm+xMjt6r/Not1bQIk5Ak6pcQL0ZcwPW1JJC6tjvgVOeHGEkLsnLCmQRq26XL5QrjHrScDhHnNbUmUv/Fj7+r/Nj0AJlIjGMrj8aihz4VG4NJvRrs1rP6TBEsQDi8cZbW7tpb/abHXX3P/FOOr9+Gp1dG6Tu8Ryqh5J4Z9CXiD91dOQILw4hc9XsV0QLx5kDbNrZx2ZWv9VBOsfVIueQrz7yJj0sE1Hm/r+87bkUruU54O0kprevRddTa8UCW1ZhP4OBzGtxj/FgVX+bmSfQ1OBQYj46y2hbPj/Y3ScZ4J8PdkcbXWS/mOoQ/yrQL0DAZDx824dzkuRfr7XaVS6p02B9RDZSCjw7z3GmrA4osvUd0JynQB+zBCgiWURD+i2JtECFQe6ww6cUkkm4oiuaEOGalMYgvQSrqz5oC2vXbvNJWfMEkrxsJQkBKtNmwjXDCAzTpBYxWPdQFMpuFmElCr2adNmv3KhFuAew/Ay0mJSD5XXplSq+7lsVe21pTk7glnzzYXo7jYRKg6HLIGXIVXlqpBqv+0rFEG0QYCIj3NaPIl7smE5ccImAsIs+OKFiPcYoBp9x7bzhXHhBdiXGLNlw9HM1mhMgZ0H8LkFn6v5edVJnNLTEYJu4uSYxcWZO7eq4cjTFqyF+Jc9j04LItCSltwtMOvEoMC9DlOgsppg++HUXq27/i5uAp1zyWIwSe5aJZk5Uz/AEzhPmXaOUvOeQpYVRzfP9ZjnI65YF/mHW6lnYaUCv8EhS1OOo6H6jKLmviLBtn8vJ5Z85EWi5aE9O/8hFqckiIrbVB+ZhcoO7h1Yb5bolAPRFanSQQRPu4lVgRRfsUseNEAEZzXaFeSSlGwKMADYBtJDUaKclAQMckyI6scavex+NsCklBB0tEOUFKsHGeUIOR+RzFo1GDGiHf5F3o8rX/x5Dnj534AgaIxHLjJZAH3wNbtue/dyxTIaZ/0Xnmp6TgbCwncp5zPejLtw9mK3DxJGmIQEoi+fbvO1i+ipDSh2BLF8vdzGZS3IV6Z3EjDTY/jCNZjUECl0yaKcV/V7W7/G867qWg6NdafWeUx/PUktngm0riZpSdixtNkzJA5vG1YMzlPrQsRzsH3huD5JGVHPTclrLRaZVCyCyM4Z3Censk9s/nrEvtMFjpu0aq/gYJIeg3Gd20q6/A8KNr0EbnpB3Fb6iOOeLF7zDlghLQOyv9Fax6pKHis1TBanBWMCbK0k2/JQDnz3ftt3DtW2fa0aLzWnA+nwEguDOGGcVDLjuy3eTRjyfNk1fT5bMgP6bvuewfebm+aco62vPpZshDkWN7Sg57jspJ5r+llv5SP73PcrJ+BDdTGYQN2XHkg6SnF9YdrmZS+aglhknPdnEsdIPDF7Ad6uAr1zyyuvAe8XX2FZOopdOFqK55tlcYxM6cFgwSDmcqhCSXVNQ/NKCnfRVLlTtYrQLZfnAcPms95t8Gbr+025dAhErntZy3l6EgBw0BGqDfKZr3QwjpMt56lJvkFoa9LY9kfVjxC0uV6ggwcn2fZVHr/lfQNmF7MGgoOBfHq11ernCyAKbMFgWMRFwTXbze1xmUFnD4VVLFUFasUzZEfIhUOeJB1/gis4MkJo+6HqtoOdrZr7LcAw6A5O96lPJn4YiDriowj3ckw4qp0NeSWyYUwJFgn/TQfQizaILvCA2nLyH63uM28bvTJFLoudnM5em91TNKndRcVV57juwVtGB4AFAzzh61I4uoMfCKNxSUOJPthSFlyMePbQdmu5JMni4rhguPaZCZltshwl79x/2lFCm3X0Uhj1sT4CD4bLKcuCoFl0tGxL5dehTo3n89+dUz+vopLBFjZqrke+sXqkuS0vvXjvBd5iN+EJtgPFnIPDQBMfrsoW5G+yYlpnPDhE6S85uQMLJA50cUemwRM0uoj3RyTWD8ZZlI5YgmXcOd5WLPEplEKBeIVZBOLYFmoDr1fXgx9iTus8G//y6PAZldXBnXVG29nG5Y8rDi+6PpjmE8tgsq7J5Do30ADGRqCCcPDHwES4W5FARP9ZOcZe8PKsmlqtmDb5B8NYQrX5tt59cwASLeEt+1oC1t31PAnJ4psCTV5eqmr+yDk5l/e3OhETMtDlDfPF8afBxmpDa3NAklLeQzK+qa6L7S2zkLb1D/zNO5iuNAMJq24gyOJQZ56X75rssmkTzHZWEvcZhUv888B0JuvoExWIk7heLJeHg2tfqaQOFe/RWoDAM3T0nInDEjrDwp0dpNS5CCPcCvA9A0bkKcbs//9iGc7H1r3RY2Kxl5NA1gDpLyvGdbGLsBpZf8DuCsVm6Zk0AmhFPUrlv0XGe2ETzDLyKgfFurEjfZoc8NEo6F8xJEAL11ruJIiQntEUSNrY1Z/IXq/rDFHXN5/c/gbzSgueytcOKEnHyyZuhoU9cNQ4NoIkW2eUdtT0zzocwb5mH08SLuBHw8aWXY5HW4CxxCJQswwan6s9B5fbBhnMzZnw6foNeESiBDOodxB8D/Lsr6ZL2n5paRNOYBelfJftnXCRvEWK1TppFyBMIQTQAw2F9QIoZr3C4HaYXWLP488eadEKBdNAdSa4sUTwQUkD9sb+DnsWX2pk78SzyuJcEurdPZ+Pb4eYXJRDmzCca4SF0obpKjaER6ZEtyEAyFu+YR44IZdoAbq60ZjITL7oJ9S+VGvuyYHtaJHdH2tKLaJOvQpkGsYlOJ7/spPlgPeF5X4kLIvX/pi5L/phQr3m/+GcvaC5AvZhvnPuloyW5KONYsIEtl11hljYE0KMNsEfEFMfJ689mc9TzNFtyOqAZC5Z1COvRvOizuJuJNDN9Fg5602O/8GfX1PNOPpI6GtthgwtyLaBUn4lP2LTYVHE4xgbR1rkLXVfL4v5DAYrb1oOs86McTxmdFGB5/YiuMghhIss0kKYhsv3HhUpKr9jdYlobodyqHHSNVSEKZ+IfucJI+NnPkqnioyNJZSsKcavEkFeflOlbkuK6O9OVvw9WJTbF5vzasRiW/Zk7RUtb78Ms6GZgl8QE3oL19sQSe/VKrsgGOKPRP1yCZ37ovHBPRbx6cBSahZleGJZsKK93J6lj83Vw92DtRKdOkjtkTapFReiKOWuXgEvOgy4HbfiMvJj47n0f/tkABcE/nabphOKqvSCNQfl+s0BOh/qk23J4mus4g/nTnxbad4jkXfJnrFTcvgFVhs+tde1GZC2DjrRlmZldWlS0RLyUsR8xkEvXLh/sXjRqwt+oOoRtkE2oRCJ1AMMHRBuKOtc5CM3W0ccI/mWd1dcR8nkYHksEvUsxGja/zBiFVYy0KMROn6JhI1CItBwZyOKvoiGm8xsqZBNwhyP5n7jM+TBevjDcRTc5jdRqX0wwcaD9908PZenndvbziO9uYoI/z+PtBZ+2lT0CQ4DCM9zEk4tlH1wnyCVtwk6rJpmGFKDjOTsmUf14HEh9+jEV9z9GNDzRjHA9RsycvffIKAjURmm2KzlU++myTHrqOCdIvFuW1mqpTFGovU+5/8FfL6w9LjlVPNMnul8XL5if74bc9eBc2Xf7n4l2CYD8zpsWAgm5vHkdL4pT+jwCkxofBliurSWBC169g4zBFpOUvSk7lifOLaLfXYVMliLtx5YIcMleK5xK/+aoXMri48JWNQQU+I2owIBDqDzo8qpZeLQCG4XszquZhFhUpzavsxTfzajmI9zBPkdqy0pg2S87HCArbiyYznKCWZxz4su7QYewuNFS7/c099ekelGZCIrN3KO+mqUnFVzxJgK9cEVB8BMoYzGCs9SrFZjTNVAMrKyeErSOL3wYwPircuPLv2VQCLGzK0pULPByrO0Tbyl3crOoftxuNiujUpN/CPDQPBD1x0fecbnE+2CT6DaOyUm34nBKe7mQJN+wsdhTnAMELI+sOANImkz/T8F+0tQIPRRyZ+/xEWzHcq8MtF10mCQsKztjK+/0Zv//Lfw95PQBHPF3puOp4ymZuYTpDKqcZ/ld0mDb9GQkAA4vAQa/Z1hYwK84RpiqOxGvbG8hdss8+r5XFHdc/uOit3lYXVdeNDVGJHk3pzZEx+c6WEB8e1mDEGtgblpV6feHUgIvW8jBPQbo/mRVcbAoYVkmilFfXUgwLIn2svv+6G0VpgAFi0eZQML1c1o2uuHGWVx5cl5jDL5OpmzXfSyLR7Tqb+wDWnsWS5E8eZHaqos9a8x68NsT4XKpHMXAkiW3ABXVaayT2NTCyYzBUGQqtU09JEvGURpUOI+rxc+e1GA2Rb7fAhzkzh/PznjGiVxsODQTzMmxVrpYebrAOSOwqe8gDAW8ovL+PWKcBGAN9xrUpKMgDt1FYEylLboOMD/4HY9OToQvWrWBx3InpS5AHCweZiUV3qR4VeIE1rSTmHBv0jCwOvqpG4LO9gNGeE5UhWmzFII3UxMZyJ4KbrUTslS/eGcKdLcztR+FVlzF1akl783FcuHgxwi5ZYGDhdjyOQtOZvjtKgqzxtA1Xl0to4ius6aFrDHw3X1vP5vqVHWWgThPNlMjTbCnPcnKYElDbfszW7PXr2rC1kjfgMBsdaByzmcliFJT5lEgu8HNxbJa1cUh/Q4+2RQn0am8mY4WSpg6QUBCBG7SWMGtaAgJHGdTEP5QRCauuHsnw49Lldfn/rpeEEJSPh8V9kfqY5VAJzGjLSj9IF+HxzXptPzHdyn1Pp4/c2FH+G+PPK+OEAJ4Eu93GmB+Vi21DRwkM+WV3BD6GRdxdkHJIEUY0okz3qPksFYP1MciNNn+lWqYFLbW9vQ724P6HH9/pgwj9z3Vng4OUiXUOblAVJTmkHQQp2FTrIMTCzUMn8ERESILP2iEa5RlOZbxhfSONkhYf3q9D3HcJ6xID6uTX1n/ekR1g3m7lQK0hZjFJeIKcEqKbLM704YptFSTre9HHt5ZSrrl6XJ3aDScHrNge+MTnf1S/GiU1meGiZlI4i/ze77m3zhswhYFkadZpa6F4EV4FR1E5fjj3ee2tPjmVrhu67A3F6McYhzMLBCUf537btZutzzln5ZrOT8cTizs22DWaTonKvIaHHC5g/BLZ3MTyETnhqP1FXqUosrhWXyVwAYL0FjJSlxEILzuJ6lzNr/qwfQnvlI7W9RRZa6NPirX7NRVX0ZAeCkpIgpphfhob2RF27+ZeLofZfu87tQBMHOcj2dOHlVbOC4v+CuGCsJEnEeQjIRTMCdVQH7Aq2bk8VtDrsABRLJmEQhmxkm4PP0Ek5dac05aoWDdzqAHmOoPtei+BgZR6KaOU/twHrjskWSaNe0ZO3cTkgvbqeMUsJexDdkWYCbqg8/hKFnJu6z6qwhrrwFDxy8+rVkF5VUgW0x70t4NpR5IoToZpecp5+zt9wlu7e4dOhHrd8lWOpX7mTCDB1pwsHDKhiOcV1TMBgIpE3mUMYrRa64Ou6K/CA6b/06eyzHy8VmmJgtH0vT1j8H2mRXmQzm3fMxVsaXZvvKE2eq85tgFKR+2PM4mZ9AVWnfE35phegs6Y+txHDGlKjtNlQFwjUG7jwI5sSPk9vceeptdBCjeXA6pFcW6hA00l83qPTinMFIzWmscLC++lP2darTQ3+IIUhzXzfOmTp8GX8+e0vw7hRx5FJyelevwsWeu2SKtiYSax+Q5gzQvpMzUxvdd3b2c9Mh1aYH5zYsz8oeU5HbmNQl4j8B5GXizjlnIGD8HjfKZD6ahtyux+4G4f7JiY2m1XOrT0J8LcKB+vI4xarjyeiumlhvTDa6i15RuCeX9Jktm/jE2ZHuNL+vhV2Sm03ywO/irFskFPFPmDxmytgR5BqNC6HH5ifCplDzfdJ5i3HsoYx76XLRbEZDVFx6fHwPgzFjQUawNvSGsaebUz0ms7/U/V/XzKz14++6ssqoKRL23m/FUeGqtFzdHnq+MErcgE3r4/Jv3Za6CEXHunU/Xr0X2GI9ZIvgx7+zS2HMqINqxKI/J6uWyJ0w+OxidBG1vA7XF3idRYgQNbqjTqx3CASn677HJCTzQBsLBNLkCC/1xvlcmw7Cz8jenZqkAYjsZzQzEr1r9UsWd8Ddj5fxyNM23xeAnomXtJLb64EzqGO2hZ5I5mzKHidgXxTkVRB8J4dzbBeQ2JSsmHo2lQgGjIAActtT+aS7WHBHTUktfKOdiaW1jW7K5xaFEk1WoeyakBwyHK2vLRMWHHc9l+MgLWm8XzNtj9u195gY8r54J1CtN0+Rg9TvbUzVxGbCbVEFTjdi/vdZPjnlR0Bvr1TBB59tWUAtQUa/IP7v1saa7e1jCDXcAkrpc0pSMO7t9CEiH2ARDd5l+ySo/O5WYVsccShc9MzJOE/MMT71MspbIhvrvuAWsZoXMWeaYsYX0kvgMlB8xGpgAf4l5YzMc0bb0Zea5izrjYxdRaQUNHpy9oe1D4j6VADMTt9DLHpCn5Vsnk0HSZriZBjN9ciYlvHwdGbK+WjYKtyZ7ltdGDNa8l0/dgVu0bh5cfLa4P5DOdsbI3NxnnKvVhgvuvFtvdLnoea6fZF31x32QBri3zK1GEHdxCxPh0MOv63dZNQFJRO/Sz3W5I63sS/aqy6UX8GGXIeicWfQcX63XkIU6cmceuOuwtv7Jt8xgmPoQGWPe2qh6n7pozFtvU/KIhz4ckRK9z0FO/GafIhc9wZcWuLPPXGO+tkTJMzvpTPlA3qePT8yFt21rQg5y+0HKcywkXN30binib1AJ3stfNcjipq9d9dnMyxF0O/XCslHUA3qtxGJP8stuT99eQVxGeqUbZQtn5RXAZLLrvFjNaQa1fPWWfBgQgZFZFqF2U6yHS2twh5x23xxhrgy1Qt836MuEzV+uYPsLL/gj/nwCyG2d2Zb9nIc3k5JOHH6ARxfPmzf9eaKCynFAGfVB9x0BA6rWcq8LuDp6WIVsBcZk8L1FSZRdoAfkk8f18XUwbi9VuBHoaYtL2tlMBE1jWK1eQpxdKV3mJrEIH8aMLGheBSZFfxFlSE7dXxPkZLEYzfXCkzvsDieFKWGal4H8QGwghCs3xpfl6KHcWNJO8HRmtBKTAn+SDGc94KWewp6oJlHzfoP6E0GvdpL8DmYdqinOGrbYgYOV6R+LUCOFX/0JtyPrgKhTSeUiSWja70e/j/PA/HmZn8rnXIF3nUuFhkApsP3m8JQ2ikBd2qhNwkqajNS4Uql4MIrr7YXqTjDQhSd1Roc5uAJSJTPAWGZD5olMpeQ79BalXNcY07dBSHk+qBdJC9TjTZJ79DwlbS7wgposxACKcWdYs3QAUkeAxqqkFitBhUUGBwYiUgUihGXIoA88+GZPhFRNAt5n4ab1p+MLEsIuaXygDil0jEZCR2KR/BPXMOPsWDhdVtSrWFzdWTMRJXPMqWpraXoOmdmkD5esWDzNekGPt1UKebO+RwmfyhdJUUg+F6WysjJ5r14RTG6VqqWpSigyihOCRDUJdmVu3ctRNvlxI+Asmh8E8ZMeSe8ptsvmCL9aoRn01T0meXLmkAVqNzJIzIR+zHlgofyohaFbd42crkCYWw8XNz0g17ECn7Xsm4OpqHBvwm8NT6tH11MceUB19DQrXaF4zPMU4Q8hwZaacFDLfLXrtTbTsUh+oDUu3k0U9BCmKp/5Fs4Xfmmx6Sr5evUG6Q1iSo+lRcmWJ0aUfj4j2gG5iFKowwQ4EIMOrVIeT79Wz5HImiaiJOqBHzPpB4ikNJJPAE9vWLQArDimIHtqGhv/P1b878hpsdnAsc0YwbLWHtGIAeiSPLxExMlDDCHwlmGrA0ZcI7v0LAnfvMEKDrCCh6XcidxZ2IVCIYn5+6fFUX0xIqRm8SndAaXuzDVo9GHxXH+hxhUkBQEbGvXGs+1WP0gXhIFdYIOCGfGXHtGgAAsohAy+a1xkalTg3V/DVezELaD2QYFQOpdhWUqZ2stM9jDdxS4AacYCCDS9P95raCQAGWo+uX/f5S3fhthA4NNtFkmVSFNa8R3Prgo7yTdnLCqLCvyB/58DcXcq21YcLz8xXhtrpiZaVVPiXR+LVdbIKuXF6+ng/C4HPLZs7ocoxJ0sG1EMYgJ+TuwaGhPFr/l+gfdsjWnsSeOLE6A9rqFjR5RrLXYwbn9Uk9OEz2CvfYy2GBliEsV3WG+zCJLJct3Q+eN2CQNd1nBZiFFcWq0pkla4rsN1OjlzSQo38dtgD1gvT/+yB9RIHsezmavWuot8OwBQcVycK+EgJZr1laAaaD9tZNVJzcHdbaC8T/1hCR4i9b9rlPA4W7NzpYrQKeTSLG5USUGuBzLnAp43PoaXtDS31oFRxkS0B5zt1bi3TzaRC8hEx2K76fdW+tPdzK5yYa3UGUIoGKoQjqTzaBYiJPf7Iidba1tVkf03/CDlJGRKVX2zKsBht7d9YoRlrFNWZyp1FfOXPzueJtIp/mc5CN4K6v+aKRYKrKOVHyZFAJQk1b5eki/nRKh0lSjmgZ7w59nlLZgcPLlWzjzs/IkgVL4xEbnqcUR2Uzi8bdq1u4I7kp0O2v5Avp5o8ITIClAqBEbwkTFRFjPNlgRTcOmRK8W6Qetxw45kYbgqVAQmrBmQ+XASNRfay4mIW15qRmVo8PTpvY2EeJ11YTAd/kMSrePGvPAJeCCFmWedeS6zG8oO8qv6ItgJ36EvkgCbbsZQ52byc+90w2HSSN81Kc6XZjdUOIfaLyHWZLI6yNFjymGs8LmBzCPRikUnbCYQSyTOaXCVb9DS4RtdSbtcASb2W480mKlNwVOp6I+JOiAWMqCFi7yR9GqzuZK3nXvL3m96s6dG09SF1ZO+BHpTbk8f1hxX6Q4NMvRFtWGsH6ZEdXlSztSUuPc9qnj8w2sgkawgCxV+bfAWFz2Y53bcux5LSsCBQWjw5D4/Bo5JJyhmdwMa8B/GkTBkxrevJAum3BmxYH9oEYhisPVtdLPNHuLq1qF8PQLScjTssx0Uy8Ylwh12Dh7ev+Zlqgoc7HwubK6vRF8Hb2ASLJA6/EIzsKHx3DBtW2ezVHxO3Jawp4TXH3SEJI5qRt2L9zoZu1EpTMlhBstj+5eLA0ErJPoW4fG9BW8aQAQgkeSiumDGUlif/s8dGXoQ4o2Hp6HLGsRRMFKA42ppG+BXRsAYqFGO1/YX9ISFWOzk9FpMqCnACmolRTeyhe2gJ711aObDSP8A9YQgJ8aYIH3gkxPcs44sKpYrz7PM8u2IPd8U4cGqRwXY1vyUyDDKmsqgTUKiXcNiaR6RmJv0W1OCJ2BtOrT+ASZK9L+zKBtzYCnDl1PlZkDSgZxWAIReVj1BatO1V/MiIvNctybX/p1YEWxZ1mLtMR6R6XSofb7/km6r/Pze70dqSu5gVan/xG4AoNDw8cgL97sgnAG8AXoH8QCpfXh0sltW91EfKyrw4kmwCdgN8vSK7MM/TJ4un8FZunESnPngE5Yt0I+sAwTM9EgZuZ0vR+v6FDym3EIrHRZiroB1xwmcOo1D9OFBcSNPn8IfG3A/bjjqb9YrSEml/wRriZR5C/bduF3G3rFA/vO5Nh4qBHPO4C5qscestvilIhuftIR34x3GG6Dl6KpSwQ43A6kEo1+svnxhFDyVrnWR524bguydmGxKhwjb4BhRFZiOBIY8hH3aXQAJqp4E6+ZJzzQeVJXzPXXbkZxquggK8lXPNHc4ZvTFco4ffGfzcBMiN44mNmQkXQndGtV1BQmIaqjgC1tnrb7fbqp4c/4xNUnEuixcXxtdaZC4jD1m6Fn66xU5nFen157s1gIBOCWstxB4pmc2ejiDTBvu+RTN1qNDWBCKqnbRJjxJIoBxfWDDT1aeHIyJFYkAqf2nKdLzQOJN9TGcLqp/xexRqnweys0hb06T6f6tsoRiwyDysMX/7iTJb0zSj/0Yyj9sAWRMXNdFU7foUrbUm/bbbLm4HVlgOoWmmFQI6JxiIHMbKr9IcYQAYrQaZkT5CK4bkf5OH0dr1LVM8lu5s++9md0rRJKJUrKWk9qbl4kmuNgD8rB+EPkGj2BtqJoQrn0nRjdDsHrLmg7VqNdVhr9xHE/wv2qMQYJeW925FPNg8IdmmXYtQspsILG31KEHzBQVz/2TaIYl6Tbvg8dkNRNZQN50PquJIKkvwz2sD0LfdpGGRwUnUjLkxtvsT564PPoPGEkf/w7xAy8jY/bEAPiwHuWIVLbuj21b96hbrkJksm6K0M2fz55LOiyBbizTWsR9l/Cl+UcaT5V+GlQ2aiptu+O7C8XcmVvG8NfqjM+mdmPsnBAEBVC4ILgX4Ia55lg00WNtvut1QcvgBqAY1siZMHRIFxwtDimdC7AJb5SNFsMcxhuW8fglGxsV4LDGMJiKIFCRbQxiTjPDVur2tvpteFDaHViTrsGgsJCx46ZkxRLYhMfzWvhefqlCGuuUgalwC8mp6uu5vpaezbNq6AIm0AuVzbweq4OI0Z4XRQv/2bJxBc/kPkI4b28O1ObfhIlTWt8WaDRZulU2w+Iclo0slvUdcvt9UqrVRAZiiEMNJDchqeXC4vQbTGfGS3uNyh9c0FbZ5awrXpiGPbWUXW7PXNx2UTBmLhHBYwGKXxDeKfFlGhPpW89eFROaDmvf7Sy4C1Ca6E/Dh9gk5bf79fy5hA175oplSfA9iUVcRecmG/atRCOaBXlXXBQ9hNfg+G5zVJVUuaP1UPEYEIFPZsQptsM5JW9NNGhQzybVmZ4VuprB9u6j70bQiGvFQ7GfrCoY2xF5tKt6+7igFuwobtcZIjV8QBWtBf8waI18LgzdnssR+3ua3c85FIcYLc4BYHvBlE/QrPa6XqDjsj3iXheF4k2G/WgmKT/PEX/kRVthAEWWOdJQP97kxJu+85YKoPVAlxfAC5zjKpQ90gBSnMDQ5b33xRWC7vzHFjETSpi6d+bSPrOZEzpoZgY+vhzAKHApbhOO5Uqu0aFpyYE2YrVSM+GkyFTzxc3Cw9NZy8IH1phqvpPw4iw4pLSVvDRlxRlyVyQ9kdDIRE9jHSMlgOVA12YkwUPOC/c1AZaqGhdgT/VCjxnlbvI5scsL6ThlrmkW5BWseNoZvoM3c2D5Ya02EISFwc9O5BN+BPqOHuFcSMXeir5FkE52SRiZtNjUh6cAfnxwRZUYOKNqvjq2s7H+SUS6bNcbpklJH9nRJtYmdlQER/8DAHEAixxZKYtiun+9QBzUocT3FpYcrg4cOh/xahLMwLVaKE9MkHtvRyZUzyzVe9/eqslMIxg+wNDlNQLFNM9NVmm18d+Yc36UUMdX3BcaxWschMBV9LdbXGtpcV77wwWNXuiqQsL3tVAZa9tMii8d1eesGEw0gSGS24h/awM0NfFKTRRUfsbkjvq5CWLS/6Ks06G7NlP3Z9lM2pcIIPATs1aKMZFm2vGecBa6VryFb9dcUUDrOEt/z/OmeWJnadzW0kNwMp9QoKqduKfBoO8ERWg+T0L9pxhCOehsFhwDdc+UKcGgzL3jk3uFp5BInSR1iVDVYBx9JE9uFqA+nHQMH3FV5H45tjA/99HXA7621ZE6Q5PEApQ4ha7yhHbxD1eIey16UZzQzFbisQCQWPSyxqBQKAil0RYLYm3BZev3vk5Ld2v+fGs6naTy2BZLTA5Tk6fTiOaazaRFa5jZPipJb7Dyat62khg6Z0adJ+E90YYyO+T3nPsQlYHAyfsmQz1EWvPvtuUe4gQWUc25PR9+S/xXIMdcTXt5sHLIMB78OWnGKLXgbtzwQfaKo67vLjy2WyN0EVTBYLaoHJnwTXmRp7pidmfbIhUg3e7xztLRGWEd/8GEmCnKuO4+1KUFphdWNKmP+WN5gMLVqOUfuZNowm8sKf4BUPK2ukBC7Wc4s8Pu0nzgbGon5ST+VxFDmOpr/404jvdKszOvcayFsScndpKQ2zwlA9P+ta0V7fjlLW5JFDbJwZtwbcwMjOGgN39GiXcTdtLZZoqBgQIyHN2C8GWvssOQzK4IJ/fdqYLpSmVLKRalMW40Z4zD7GOAMTjPdMgOtIpBhTxEh8WwucWeMv6h81cYhHCJRq7YssvA1s380rznxLX7NELtSHLTpnd+gsNvNfXoAWELs9dj7TZIf78A85V6DUEsp7jfn34Cd4Qx3MIY0KUANP1PGit0gaOcqzjGLX5E0BX+C0vlYpl62FrmWslo3b8h5GVVFwPQmauYQZck29qum8o3pi05Xe2mMUQ+9uwcZisK+9FlnlhgTAfKLD7LmqqHTc4RtuqNAEULS/ySJYb/vZIqBcYJQIIu0/1rCqcgz1TVq4c290Z6Nm2U1hal5AYgKCo5W0Iaxyd/Xz8jMjAzcXsjhTUUTOpzlu9IkNeEgWhnrs4RyJPXL8f7H6PvIV8Blkw1Tg6d0kVKKdz5I1ujvUEUSLjO7fkqZ8uujWUu1uxukD+NCX9JC8wvzs+1/a9Xs0TGf4ddyu8ITJ2GIxoIKtwyxGz43Jk6z5T7BhTw+g0iCDfR5uPC/GG1/hbX4Hlh8vy6zEd91JMiA9SAPqG0wC0PN2BZVTeRHdt4RTQaIiyYf+m+W7A9CROnu20K8iNOexDbT3RYMAfkm2oILjdDH3iwPnAhrefVwunbMN3d3OV5mXimwDFsVJMNO7cWv3wU52ueq/1ETmhkx/5C2fBC4kJ5jkfVhK2mAFpPJ6vLwoeI0vmed6bVO5CdMya3LEVLKO6sAEkMkzFv7b4T6G8SeBxnQDOehJc7Q4gzLsS5vmUbKntVjw0NaKHvz/Tscf0PO+tVufgv5o1YCEZm/Lewrd8wxZJyAceBREnsx5xY8C1myeff6poOepJcjegFwp7U6Jz3MQqJV0+bcf1g9IGmauKknWCcm9quZEIhIS926xip7YtzRXHLp+GQNVp9H3yHuTkCXb3vVVf/veYbtAKSQ77qWEz7ISnJOLkREhzrgsi5LXMUs2cYjn2z+YVUDkTi14OMsqXSYSBw6WpVIk/A0jADXfhERkOyP/iUyyBNR3NDulwlYSGqIr7RThIsnYi29GXNm97q8LSzx4cTVVEyTvvQkuCI3mfLw3ELLIezb+x6Nf1tGTucJUDwcd/LpSSDpzoIkdCVxJJCMC1L1hGQJ3o1XLh646/qlbi+xQtOdc3a5UCcQVNa0eFuoxaX9QHRrpgjk77IVFdAXDIvVROiWS8mMiWBhzcIEHDxmAkBsy27zVRrqnsZr45PWDXtI7vExCtIZgDgMLUmUbUEKOwS9rrWoozjiMXaf7aJDUZudDpCdvql+rWb+GLf6FwjYspD8tR7EJaFEgHuYT04KOpPTcEHpb7QKBKuVHSw341UavNX/NU4BJIa0wRdih0m4hgMZ090eYqQiwx/t+cLQDwVg8O80DXCHo32cfgl8TLiXT5Nrt+Fi34A53ZVjNiXfqDVLKqXKnGApIIcvYf4vP6ILXbWcyqdr+p2UoaBemoZTeKvzLRpxSv+uqaIwonP/kps0L9U8j6Xz7PGrdi1qRqYeaOIDb6D0f/TJYvx2ZGG4lIgJrNQgZ6E984fgv6FYbY34o0DNDKHTqngJAm/oH8MbRb2kvJv99PeiItksrhSk/+7whmoZPsrqSx3fyEbissEKY+6yWXUZVk5jyJMcoQlHFPlCTJG0TE8JGSlNeo9oMp8gmoSYP1gP+KPmN3r/BDIX6FKWbRhcHXIoaRrSOmxEYuHD9S+ShHYknxFnI1hapzLetx7L/i0CgSRl3TAByjzb2DlJji8xqh3MZs/nM7k24S52QxYiL8+3CPbSSeh3Y2kHFM7wCuHCODPkBJagGOqUUL8y0nTTURH8/jzf0jmpSU5zAni6R79uIaoZd0WckiGP1m2n4DrHLgXWJuEzj/MKQk5cYiClblyYCK9n+yBB2RIKQs5Dj/g3IMb8TDuNHEX7qCT+tXMcDGYceEwp2bHQjdmATpK3fkVKs3rv/q928c6qka3C7SrX68ozCPYXLMoIMyxuoy2hwXgiyvrZnnoqUKCMSbEQ1NmMrYHEsQ82Ladky19t0FBgREiFxzJaeD2yEo2cHs3P1edEyTimP7pGKECMfWG8ALy9ggNQKeINIzXCQQeYIabtrdSD82Ayagt74kB4eX8UP9+bWdbywaAoUjy0QpURvz6cdySr1UiUCrJ5dlqA/iFblqKDulYjgO4WiWI0o/QZS8r1ieU/AV5zDi1uhJNR3GQEIoL/ucwqBlvNjFgkM1NeLgpSdBSk0WxANdhQH0e9Bbh2bdupA8BJHEnlaTZe4wakBknyHmjodcFoYY0pZhNx2Ju+aM/xhxgzrxgw1iIsfGtixr4+Tm1GKaUYlfW+KDAf9SZWZt/GgkFtim4T5mqRN82MdndDwT8+HLYeRZN4LHWXv4USGK/k54e21YsOJF72eiPhOiadIUpeLuyIRrW17Bl++npuX+rRD1fUPj3ZtW+JlN7fGqzCMgOAMrdmEm6bKYN8VSj5G+Rycj6x3w5daVugMhprqq2f2JiPgLqZWNx6yyssRlEuBOnfTjKmjI8yEcI195KEoepocsOTMrAjOaI6Z/2uDSueDWj2ZSmMxPXfRPWZWDREIHc2xwPEjW9rBWxlaZnqP/sZA+d3ZPLNhT640SaM8ZEv1xaUf2UU87pRw9Dm3o9YYfPS/EQkW+kgdN1V3FDcOXUWS98vT1jRth6REQkSyJtW0x/IfsRO2Mcrw1aN6JyoK8t0LcR9EUkCs6+o1HknuBNKGoUZEt8jO5Z6LcAihnTS7O72os+1fhTV3HKhchOsO2AgY+6NDpI3nx5S2TI5jEDqSx1SFi8cI76VXmFtHLsi8+eyJEqOjFwqKm54l4zAsZlqQGvscY8UQANuWlYOoDNbO5EDwZle1T/NSeFJdPdI4PNO+Eccd6jItDHc8dObnZTysxepGUND7Jl5M3aReYRiYa8Awd+20J6NHpKRU5mHbCEiHPwQEIThuB3STDneJIZnbOf4jGxgGRuk7ErCWTT0THKqYWYb1BriH/DOtLCHokOezTQzFONZoDWTT1KUsI2mJLApfeeLZlTSushHfFPgzMWh85V01vxZLt7liiiRp25xkGlztU6+oKqO04YmRhb/rHVrFmnZAViLL9qrfGUlhD+khm6PZ1dV9BfEnd6JIb2mk3wECrw1oAPhUcUMf5gTMywTli68ZSHrU0K3wQ9vCouuOZFhH3vizq7besiu8KdvHEzJQkdXDPRHEl5ga24Vi0S9FzTiP5ZqD2lnMH8vQv4JF3sQ1gL2Ewst3ck/GoAIo/tUMzTUoF13dy5iqyDt3VZMK34VLOrJ9ovDPeQkR67/uIQuJP6iuD9jfDKUb41yeiQ30vIKlncI89o15R+g61QOpUD33QIa69e8HcxEFrHqmQHUyljopsN5rJz7vIeQzXki0PbEtKQmk/J8MYwbUMj9GL2dvZScICscc4No3LS0mzwr2Wa275KBVLBT3ArXQhXR2mAeMeEtE1oGQLeYDEw4voifAI+ztKFtu6/GpOyYwlU2oy0JyLO0y6pvCmWHmsyJYxg4IfEmtkK6g/DVNT3Ef/Non4xkwTz7lrcR6puWOFd106blcvP9RCHSsMsEMR14moyePl6nrBizXM/IASvi3E9pseLpICU4e8+NPeJAgiwrODrdCclDytrtOa4AKxpoQkgmWz0Yb0KEFWiGjh5FhYyOrin/bt0h4xf6XuWeZhyLIZ5AQxwrf51zGahWsTp8WptnnnOzwktCfghmfRNCiUoKYDEmPPGVSXSZ2fHsIMtR4iqKs5Lt+R4RhbYDJtenQ0eqszvbDy+kj4AjAIFL4/uL3+yXlAyL/HKOhI2UUD0MTWZr/mtvBIRjBmDx9EccLLvNcbLTOiYPaEMXxkJQGWPNYLpCNhGKhXl0aZ558nfrupb20D73BhpoVf85oJqtFcCYFrNidEKUBYARsP7yT7+RmcTFOzSMxuy6VcMRRGDRNz/6KZNF/XKe7P7AqhyqBg0KZyDWoMANSKguN60VhoS/7srtJMC1EyX50uNJbVWZQGIEmLCQdeEr2kuUocI8jbnOdhDbpt7wGffqxIpFdN1A4euAwqcUa0bXsQxIhuox320lA3jvfRL2OOS74eazOLD7GLTsaKAuxpWmKSGs/DjA9LBZN10J6eaEZjh+l1IqFOO6HZ1wgUaL50WcjY0rJ6aGj9qxTcYLWlHICSGEmXcj73yErpMNcF0HJ5iK9QD6sW297AapJKkQ4538l2hEFj6U4C2X2b3LCehxiG0ncJejspFdFUY/jwQwiCSv+jXggnBPr2lk0+zCzT6MGgvIXEb8Rnk308Zq62Dt3cH/jRaZpczXb9IlndU8i/SGAGh/9kWuAD+290K3EqoeSlPEDXbPtSw3+9lk5nyVyptV8w4ZKEQMhDafqZyQPNyvf3kw3SSx4rMrurct3wkFv/FvHKFjjJ6R8kBPaTn2LN2pNxCGRoZS4VQym+gcyeG3dG0n1mmrRs2ZGYZIkDrliZhHxUWBX5Jvml1TfmYW3itDTjmKMsoNDmvJCqBd+dTKUEW3hXkHqEEit+TH7SPuGF5Xn1gf+CH1Rb0zIvLddaTp/w3teJhWpILUFrBjYxu6xwFJO7+PGrCUfqX2sl0B3ZjVCltZ108szfPbOi6RT7MPIKUwhhNNi7J/jQwnvwcKcasZAEuAbb0vQdJIrQUJ37noV+KPDbG7qt8EBCg65yNTSbgwFN3lKwR1KlqnC7PxoD6CfJ354LZLUwmbjNh9uAekWEckMhJJym1bX0lNqQUJbWXYA9mbXYEYC34wukOGmL1aD9eHf8NQRjEBKe8JhX3g/zsPkg8VJPoAwCBdNia/WQ/QrvB4Kw4TdvA4UkPLIhITPzhANdGX5R9dGJWAQQTzfS7/eEj9iMpo8/kW+QRsNQJjvIczB2/MAEcp8fdzFTDFTYwF8/gRZ9jbeypsMLCxAOibD77xPFmnHm/CX+2M/lvWZSUnkd0a922Y5wpjzjeLlqpDsRf9cA40bqba0p8dRuHy5Dzv97O7jap+AxCdIIXHdtfpwyu1O6AOkKNuFiRu8Mrw3qQZPl2MHCpmg9n9+PDDcO7GwqNIc1Y22o/GK1KTADW23fK932zKby253LodS0PMdQcIgsN9UHDW7SenkxZ1GxUMyLZnRqijnM6w2q5BKQCrgBAstPJ8Y0uy8dLwtVFeE4Sr8qxuUutihh+bX2h5qdlPDgBxia4yJwUBDkI49uZLDIs5S/dww8RfJO2f6g6VZtGYOaNy0+/aMUPLkuXAJEbpjcrMBjQSH6D6lcHg6ln/JYBACcbZrDbiC6aWAH58Ex7H4zKnNK4nDjBuK/pzU7PY7k/62ZRpU2oXnZN648Hvn52QgtdvYTxy1D4YcCZ9LcVZil3nqBWI6HcKRKn8OKKcv0c1WIIvCi4xhmh1JubJeTKlcyDOzkEmWM6zSXOWxQ4pKtit3iwrl33kpF7h22to9ljVsH7W5DmT46XAaciGbo7+5o584k/TvBS3V12agIOJ9n3WxR/9lFwfsBXeYkRY3RVrHGwqs2mloJWiFCuu9cZ0lZIj6pfGBddeBqu6lgsple9CuSV4AAX0krmGuJmb59Iri6q1HF0eVoSjo3kkbtUeg24RJtMQRguOoGWITpPlCyxSWRJo0hPYalIdIwHQivRj7dZ46+dphcO7v+Cx7xmrFqIzuoTW31PYdUwlxhfh4Jw7JhswXZKQvyNDPfDVz1lmfeQYV02Ndxm5LxQRnWwcdSYF2aWAgRkc9DQ4Gl75jXEhYiul7gzQQa+94g++bjxtDPLsJj1MlbLX8M318SdJNKQdqfv2MjCEi1fH+TEQ6N+RYa2VzYS3g6x2r7VsZK/vHnxuXDKhhOI9klmcGRjvNOPDLiT7gjF9w9QBKtzskXz8pNAP3JH4wPeKRGDTJL4MgpQ4Vi//wpfIyEPF8896+P3KXP3YrkdBdV3vfEmcPZDCxQ9ChCe/xNfMxBt1gygZHjjEyh9voRUf4v+b91oVcRPPfZNYkXgU3J6RXEXfcvru2iWJRpxCDH8VBLtSujKGu6ZzHurxCcjOgSwKn9GwBIPO/OjGbZ06RP+5jvVnaKcTPblJQfbT2ND2WMYJiYJIUYXicu+B3qPYrrVRzwJZ093BParDzpad7l+0roqkm98Sh11SWYOWXfqBJMJLZR2KMf2/z3WDjR7XYoLLjriarCh14Hb+K77pCRw0KKkSU985/0DIkjwwtt2WAxdtt61pFx6jAEM51EiLXOzaDgYHu34vqGZFPr6Las4pupUsv4cTJWXwpiN4dFZyzKBAbnvbKHf3CYE/h0ulqF4ukRT1MBApwtYtoGjfwHjqvkkUatL5MHlY1pK5Tpk4CYoXx5f+7N1hoJiHWEgFbzXPbBc+/mapHPRPRmLbsnnI6UoQDTuIN7ZlEjUISoYduPoUoMK/ElGw4YDsBrjOiDbH8XMg/XrONJmalkbBPrjOmicb2HAzH8qV+VB1GEij8yGYRJPDULOX9PQ/88IbJLOh3Q4KGuOlSN/u4iKJxPEUZXuHFP07bZDhbRTKKIkbl54mw9zJES3OhEmnAWBL/AY2RQER74siQ6e31nNBb2H6BUTSxa74T9nCJyyV0DTyszQwSaj8zCR1FUAJD2m1sFpNhwtzSpKCh91sz0Y0doZ+29CRMtPwU1JkR9mPw+zm9M3eLc2PlkvcDdzrMJ3M3MMmXTDsNcsp4Ln0rSAmYzdIvxItxCOQiP/Sb3BGElFN1rkpS7FAvemVAbvoFJsqW5C3ZQ6L9LUI63rQbkRFY4Oo7C+7+032sJsFhoXrfEHOsZ1RO3Kfw39yh0FoGfJvCQK+D6hgaNvlwlHz+A97soWI2Bcc+CYSWicCSFyGCBFnQMREOprzHzWc1rk2ai2Nn/mc/4WHeuKJO6+8jv4+X98sJUIwld48YHswLdyrn+Pvjn4YUF5NOdcIUr274ov/yjUh3FyN0cmhB/5ezSVmwQdyRYgB2cUWhk+yttQWcYxAfTcZticmOkPRe3rMhGWLW/N4+wJH2XwNCVG++uINiKmABoUDo9f8qGvnKugvz+9Rx2rL9D6KXNK0ft3EUI/uaaKnARmMMfLbzAElP84SWA4YxvqOfFiOjWclzFpGUzHhWsP68OsfTmtZaqMWmK8rb9bflu1n4LUFk08AEhKpgyV0UpS6R72q0M7Ybs+j93j/S3I/CFPUC4bfR24Rjayzake9fnJYi6H343zhAkvzE9C1KErnCsmxRr/Dn/UsqHyZ3mCD3hWIXrNhBotRPzKdzp+WbT3Ht4E5tXtgo3rKiLIZMK+665GWmmOEzTs93tEaNKA3BGzVgSsQDtDUPo430O9L2vT3ARFayXmY/7bAC0xwFGLlRUPGkvodkOcsNHDJgPlhh2x0UjPqRG7DX4NbucioWRqy6wgVcNIjVF3J/CkndHQAcINqasOZTNZ4mWtKfvKyyxMGPbv9faQnf5GUU7IDUM8HA7nO2PydyvUT+0VfHnmkW/FGEwwUxOBU6vUWpKV0jK5shCWByXWTDwTcBPivk99A0b4MCnzIKlnk9pd4olaOfA3kZGErOIui+ANpigi6z5hsLnWVF39lh3O8qPjw1I32OiVobspUfJNAsEwOKlIBppuZRulu4JE0xwQS/FpvOL/DQJRYLWKbovltMuJLrdDjvG5edFKdEZTaump3otk74wsMsj5mtiBIqaW2vUYObeUP7ANUGVuMqfHaBtnQfwGUXKdVmc2eID+xgDAkbK8PIEYb9T1CTVIHC5DIAdJMs/i5eSYVxTlzBvaM4GQh0rxYCL08aYpQcGaKfVTGUwPDkJxfa9Js4ECS3kyKb3i84oACNI6AbpLSA3lw3RwdppJS6zZB5/vsgvPjXLDcty7PUz/WcTszmQ+KFi1F5TXxjFJImYjwLcOdbNxI+7X8UbPqTaYGllzaIjVwbgWa8XXxoJyvCp/CR1KtVv8ie3G+75pfbLCcFXpKAB1yXD3RK7Gq2EXvdCP1oOW6qdEMUUhqVCRDnjEMwahciGeQr9/sVkLaUwpBHGC377Nv9XErCM6j1v52nu/TiaoLJMZ2F6J+YyeD0cjxdq42mIto79Tp/cT20CUFc30aWw3f+egPV4Nh2uZs6sF2eTRxveYmoD4ZiIgI577vqPu5lnRfzQarqyMe5ud/QkL83SYmQG4x5VmqtH7lQ44j+buMWRQYkBd1F9fIulDXjXruQNEU2G/s32fqBL9dgGXXx8yepFqCuc9fQr9fkNu8GbRmZhpvF5ca6iopP65b5JWTkQoVAKq6dA0QFWf+G/ZV1W1ZvpyMBg3ZNSs+jSTkGRwwfE3B9k/kIk5mZub6R+B8QWwYJUxSBptfkc7v9avMsGXTGajte6RfBOFetQh3P2t2fvvl5h2Dw8bjfOW/zA1NkDZRlua+/RcSlybACu5CAcLsqRuLqW/MBttdC6Hv13vE1NLErNl/DmVrhBHrmYHVvwLEZdo64tUoMplyhkuPxrNTYxVTSIlqpVz2sQU8h2cnmcCkbm9BTtMqqJ+Q2OtS91IZYQVIgCRBwL1Fysp24l99uy1FMKFlr4yvJzuWUgBt4/MCjSwhVd3t1D+MZaPtau0IOsy1uBGL8TU+1U5IXO4juG8p9fMjwcyHFFTH4gXNgfwYP8U72YhudHKvcH9p1piESD1srGeQ3SS8HayLKEfHTZhrAROiQ3iA5NxuHEvPTdkZSlRgmYgyNOBjpym4J+0w8gWMYSiOsbc0vpqmHuQcrbijUD1mBHK7URyRQT5r3/+mWf5XWBrZBMRA/+RxAL8+JRmGJnyeRp9JcceMu10QhbbbxRx4PpP+vvFSqmnXMVCegGO/tKIhFid2lj4INHWBp7DqYso5CcJH4vWaG3uoNk9i36e1k78zczQZ7ysTC3N3MD6eEIQO7ytBoSQ4I8toIAc8htj3EHHC5t7vKnhIiYPEjDWg8nJXVjKGim/xFrIJhOSOUDhuztYrAgmXsNBS5Sp0sojNCszsErJ1CGgSFmC1TvaXHacJlcVTJdP+Iq8/8Ddv7XMPABSx/rK9L+j5kx9b8zbPLA2ATtmQjUrR+2RUVy71osIvqFts0EV25FYdxKz0BcWSoix/CJas6MztQkKxm48Fhtx2SKchAxu/hrKcf4umPQU9eHVGWk/gEy1/xXUhIYf32kNDQaQfo5reihsMF6xvmDTsBUVbG9GXBVscHFPxU6hWB9ehJPK4PGmL6T8L6Dxkvsq/9ZJLAWMrmJ85yYKaJwzEaxiu7+MxKKrmGWgUmb7mMyMT2eXnMLvsb5X8NHBir2MLDHFMdaEDMzDG8cufvjRNui2qAaGyHgtaQSXw0ApqDwL0oNOvF/4NyEh6kPV40aLzqMa1NqyGIKv7sauIISAt35sHdJKihphpE5o8kZNMu7DdFljiOjxcvnoJaqIM2qQZS3/ApkMCGDgzixA4vY/N0IaDdlAF3AKkdW8TKVVYkFXPqFV8OfIcYfzdn6kn9jDVq3IjLjf+Nfay1DKh3faQ7zkvrSpYy8pm2AaA3fDNiXPxBI+r7M+FPp8unUf8XvtJMzRE8Uzyx2OBiEkJ10k0H65haYrrMkO/TCcXeER865iuczIWB2Al35feQKW9YJxfkYee1YsUtSIYbr5TrOxM3J1dIaZZYXHUxxElUV/T1YdBzX3FVzg+3UetNqkSyXJb+2Awof58Qkg3SYzTc11urfPeJletzdrhEDYvaWsSO0BENH6QlfXHbuWH+ObC2Uy2c5JDnRXeZnwNgNiVbUw8yYZ1W94HExxmzGWCE+AUzd4wxDugX3HGw0zUkEbuUSsNRPThNmopkp6eT9oYYwGhZqspcVWzxUY8++n7Y5lSLXEATol5PZkhcPKp9kWbGlWRc7WPIe2GYREV46NWdYxE8NcMHQuBSy1sxOgB6iBNfKUCP3iIDjwrLf7szN5yH0twqwBcosaZ/41ZbClVUHfGkZMxNG2PW9jbQJ3mShxxiDfBfT98ooWru+6tVGxjvetSbbhqSU6xGJfRKesSZUO2U9tR8j8UF+H2iJkQ3sRb2Q9VPrBcNvK8je0y9uPJKd2tuV1Afu8wtZrJDRltRbQPrT/zdsn+ukGmqWopH91ZJYS0fzXRoimCnYSeNfNuFh9LG2Yi2neWONvO37MFHretbAD3sfV94pVTiwm3j8xLT9ezr8Q3ew5CrlzxW6PEh3kaKbXxraSXhA8Tc+yOBrTMGJB4CYRcLAoLpdQp/p6lpiozEF7GFh9i7u/tiZvMrN4+GaIkZcEN9OzvcagNEVDgno20iXOWZk2M5V5dqYVVW2Xn6j0gFXu4h7DYhzu4bC1caDd6+hLhYqasIvqoppyuRLUQLho0O4GgiCJZWCQtZuiXLs2A/4vGAZSZ333Dq+YY6HzIbtzNQUH8Y+KDVz8PDJ/UNWbFZcuIpjt9MCktP48eBGNo9wTiM1AZyh3vZsNfBpa+hYTusWXNWigj70OXKPHiMH6oOiEqKXxVzhOlx5/sm4I0F9aSv6Txo1IKPdxDPpxd3AJIT672fu4Lu8uviLSUYABnRcLeBx0PzDva6+NF526aiOUhGH0BFmkiwZZRdMWfI/tLqTU2klQ/T6Azv3q19kfN42cFbP/jNBAleo9E5zIVh24aYldqselljBwmrqJJgv2NkRnacT1zV38Nu+Tg+/PIhuPZyq18ETV6Ohzp33W30KqTBchnDE56jNDP1fpKgYD/1+s79HSVQoHwP1STX07XkavPQ+by56I5wR7OGhZgAEW3/a7qf62onX8DvUatLH0mU5AjnBrArxyPW6BIPlXO/VXDM+9vtL8Fu/vyXA6M348Ym8/NQXNOb4lUMwBhy01EU/pOccM2Z2pWYEHbdE19vsji+Lx2efVQB72HL6rty+QVfQKVUEycP6Z4ESIHxA0pMTFoPslf4oog5pKXj2460E4xd/vDeSnn4MFMrg+ORQoU7EI2QY1y0G7DFTJh0vGSQUiNaNXpMCx9ZB8VH8cPpT7ZoXkiAhj1xQ78DW1IvRH4j6RMuf+TrQUEXn3cBtgXBN7EObAK0rJm7SKDQoeRLW6khnlG+mQ2f5my4MjpPKfJwyD555KMBUxvh4oW26qmXcCE3vkBiDiCG66ZbEIXqu0cxavnedDWdTiA5PTtD5ENd/0rmqe8leV65DdXTqD7KaDAjbMn8GaZtwFTyPsFxRYV+OGlKfmF9DkTef7NFcGpdUWdcWn4PeCOaE4lhoMu2SX2tLh93wL49YZUQjlpukfQx/1bXs2BO4cRV2e/8IW1EByX8EigV8mZ0nYMBmBlgBlq3zmwbQZLnqGWbwCCQCKjE52nDkZGsV0qnwXXXkqxZ0LNZheNmVycNzk64jhV9JRbkgKpBOEHFqbdkfpH8SE0pY2MG5g3vMFwMXan470rrYBucGVSbO+AKjRGb4bz/hx1pHko9l6IS/ozpMhczyAm0w843H4fGam1Cu4/zoIv7YQG7FT+vMPEpMc0Tpe00B5Ll5NHobwPZiw+5CSwWQRAFW3fm34oN8CEp10ApT0a2qrNGZmuJWYH3S/7X7LlQQBQaaEvjp+DrMvdgPY4NQsdkJvhuOffdf0neDk19SxPaIshVh5oFlGdIL3fMAINhkLUkUScv+UpULzK7ywFP1BjTKW/sVl0n3htEei0txP8AyobEbcmStAsaKRPvUTtY4ZcpOLC2N6N0Vcw6BGxufK7mDkRi4TlxWUm+lQZkZZE8/tVno5ycb4f8ZkchF31lNBHi/kstkIl/NuXsTYQq4e4DnBW2B5I971LDUD/IbpwfiPFk/rHui8dp2F7aZEdZ3kn7cXBVvd34hHeA0hWKJ+kRc5bmNnDTN/HuRV+JvvZVnLRxne2mO+sNf75tw/BItVW6XuqoLnp4Va6a3ZBsgvfzhmurJDaIw5gtITnUiUiyrZ+OzbLDsqVc23D/FbpntwHAbbKm2N1L/VWb9vRe29L/ZgLcdRqgE8zsBdjOoU6yfOaKewXriiCC+eRnVzFuCwPUvzq+0cVXpuC1X/BNxNGsL6eRjsKcT456r0/CLvFVitpTZQ/1Kz4EKbx+uUWLYi9sHh3YNrCsMY8gSIpPiBb2ydpF0AQ0oMIi0AnA+Dt36Zo6dImydq2oNab6yFAt4OdZ/cUGGf32f2y7jUHUuux69JK96CwdaSjSRmqYVF/BbYt2yk2pbvib1AAAICv0SwMRY+VbA4f4vDk6/D3HC7WEGWo7YSe4maLkV2jwSxeHOqEL/QUwVzCJjbKdGdQsSqdzWyx9V3xL0I0XPyE/oRvGwbJtO1qtS4dLUDmV8k3jYpiV83pjVzobnGdn35tZHT5At0cziWDzJ1t0KrXiMIlxYAZl2r00UwqB2EojPVb1tAArqWqlOESLnKFI99XebVoJsjEqvuKn+vSP5TWeY5a1Q0LsKs/p0VFTGRmVjcPH6u2D9Vtp2Ja1DjO/rFNNe8gq1JDZnuuB5issJVrmlPrhG7lnhfmz5TzNuA5nLvK+anv+6OXRJWNvN+BHx+SHi8C9Ikbz29PwV7c0ggMMGLu9pt/MKFE1HyBbnd7uwPhUMF9DXka+3noVDWToh/aT89nNbSWRj+8jd1o1gXPxB3Pk5Kjz5xUufERm9qDhcNj1UBO9Ef+NfDsbiMvlxKZhA9g5OgFp4OyhrKZye64F0Sqmq7VOyan8mW+Eml52hizREg3n8tiGX5vE5uoarnEV6gyebaNeOYAEvAn1685ZFAggHfvnfsW5n8Zg4mSewpwCB6Qlt5C/haCPQ8TqNNa2khhtlR9bVDuf33i+qlkCykhdpxgwBd/XVAjjq4QmxLUSuEwN8A4+TEXtrXyZVb28CAGcM0Ctszf3+duVk+ebR5p5qlKzx6CN2grgWiyIYf5d0l+looTP04pe3sy5nQVUtxWwmQLSA5TvOAVWXSmh96W9nyDIaxkVODRHy88JjtD+SPENYLWp5Fv+Vd3KHDOp5PFBwEGUylp4x932LvzGSIWtJh3aIjZuS1c45xZegbIFgDWBDBixj7MzRWjoYeGH7J3OGe6TzH7T5SH0hkhbGrXRhdsdtMp8+hfauRlWXjtV03fNaOT0N+Yd6v7suAkPhFSXuefbTbU2v86xrOgk4YNReAqiHXTjexsnFVPYAJJyOMH4JyBJwYfmSuv5bkfdHplNBag8v/0hyIaZuhAhlnNgpNA8EHUGhKOggfGq5DaBXk1PBdSpyXMBxazyp6Ga+p47Ka2TtrMjcSRu+poXreVUgLMReuOlEbO/EanAZvdD4rJd2atj22QXx1wI7orTI/jo80xThDn3XEB4ePYY3iUhR54oc7dFYl6fiQksj9ey4VTIE760uaB1Q8qhGrKnAZZnBzQO2r8AbX0cbQhee9fnoI8zjrMAtmMx5AiVXNKJJWkjfmZdXqQsPs36d8spKexvjFBLWXqb1rkMtwI4b/ltErqfngIJXw2Ik7j/5emxClk310AuH2OXD9Sy/+08WQRY5fZblk+q9wFPFUrU/6vonD5fcclAYjPPA34wPAfFAUDW7M3eU8CMF2QSUnrD3RNSz8Ze/Q7G5gr3s++QN973bEK+Gxl1ToluAdatFf7dFe6lSRuoUK6kXURit7LHZLwOEFs9b1R4NJ/JDcHIIDWZy8YAOKghdQadueL6ujStHFQKdRDK3N0OAWUkmNjrqYuJfvWLxI0dS5VKo5ST6G0zWkaiV5/zIpEFvBZBtlqE05iH59G/FgOh3SUp10pKqfbRx54Pkf5Y2dGcxrryiwaORElq3vtv8Tj/WvKZ7/pX6z7r2ehGKzRmF6IJDD4rmjVFq+EFyPtflSIL2Ynlz+h7CmBEkhSv9xqA/7lnDHg4bxj9psG+KNwV9SvNNQcLDgBKt9FVfr/he4Sn8DLnlUSr1KHL5h2P5pACA8MBPeVU6g7PggmUzP3qyOAFmnzZZCNgquSF7RDH/qjct5/iPVgqWm6R3SoF7F1EPMAesFaHcH8sXtsSS5Piv/CwE/D23llje2AGRjR3xCpZtFKZGBD53KVM8+IKPL+b+EzErsElDccVqPzlIWCxuWaYRzTmA6Os7wvGaY8ptHF+D+zwqB/B9wr+2bZxGSfgFAwTZaBCtE0NiCaYKAEuOQHocAkm6nsPp0TDVCugcquu9V7cUscjYp0NXh1ipSn8v60ZjDUKWKuXGYeBpp5RY5pC66TUwROPrM8wky28tNgRcW12murrUptOhd1Yo+Vs+oB+P8uw6gVGtNpjy0prN/3mzsE15ztJ3423a3SgiyEFqd5az5hWAEpAwqV0L0QmfIpYrp9hwp7A2lnwG/32xQDuiBQjxeEA5b2NPoD/flI7x8+TXmzuZgn4KKTVcnwZUzphRGbij3Lnr9Y/X9gYaPaM45l8Z9G5d8pUKgJffZjLfxBH+zDEo1+674LOD3rUZiubDaSlsclu724p4zf26JVsG0vLidqxmFuDOeAuieu/4k736fJdUmp/YL9hx4fNHB+wJFNYtvbnfciJKSu7yaf8ZRicaPbeXGlrR9ALUQUHusPI4xZkkMWPXJfDk8mp7u3OQiBOIDONJ549+Xp795ylw8jl+dVBKb1YAOCsb5VCk7BJ+obzNdLAbIBepocnP/wYhsjBA1eMVIpTk6Pw9r8mvDtZNfgl6Rq9J3d+aKYVgSCGPymksCfHXTJf8JgMlVkeGxAT4s9KLFMgJDZMy2CjEI/f5tqz9HU0G5Ysj9PRoE4O9kyvSa5fZo6BUZwI87BBE5uRDBsygtOrtX/MvyN2y2X5UTL/oOFJL9Pr39Tw5jSgUJvNHQ5j9V5tunyKFO7X7TtLOXHXdpqeFYxfExNtEKY1v4m7rxqWCb+P/6qlbNbEcgfblvINwSMWIu1HWXrpIkfHNqbnXviDthvIqwo2PGs0osfvrusUpjC7GQ3e1v1jITrDNgLbN8cn8OnMw6WfA1WRRBMkP/32tEUonld+roEtyo/gpw6/HA85yGFsyrynSzkD6Es6eEEBLGx2/d0F994YLmcYE/UY2K1G1Tg2/y60prchdXQwX9STB6Xp6qdtxgDduNJlcVEWiOf8JC24HvWg5XBGQCD97hMP0UyYAezii872lWNk+PBR3ID/q5hxS2joBDnSCT8V2FvjR6e/K+g9/DvR2KNZvUcxzQD7OikSDtzv2VOHNUif/5RW3fkc7QkqJhSgnatK7jk56ne/6hAqEiXduPP/RxjGGAPJVSfmK83D7Ujyzp41UtP52l6Uh3qLwXld6n2MmFIdXq/gUm7UaVsPN15QGNS7rut1E7DFOwqdxkhgx3mDRdYI13TvBPobV6yDL2WCtMygXhGSCfJ/ZSZOEgrjFhfXPDvEkM4J4u3XzOLUt/SOf/32iOFV5iZBoeIuERXb6+AC08JY+jBK3Y0SgfBsk7haHdQ/9TF4SjSWEEVJVKYSVAxBogdCpgDnTc6Srb+891CWBsfLgMe/od66rWdFTP4Tigd/cDpl3mgB4b8u7CZkgtqFLMQn2iGCtrkJ2hClceVxvvH9UWEjDVcSLyI5Kh4vqS2MeA+O/yTB+RbskC7Tf6HjfhSWZDzCjLHjF69dFsaXwObALATUoSEHRj97odvq+upuqCr1d14PEkNbl+1r27bnky8gXUfTAYeVrdX9uLdYiWHT67RxhSRGkXqcCGafGUrMlZUg5pdfJ1zSp+XPE/7wia4FCw+vzBX9n1L7u8wWU/LgYFr+E+9d/tuH8sGa2snNqfElFuMydW70KJ1Lmc1WC1vODbXnZ8SZEQgtMXo4KwHI9/dUlkXWD2zIpyyEHA3w2+xgzmQvbGkNMfw7c97oIYfyz/Rxt90KvkMbZP/SAYJk8DvGvTHdpiIUfoCeDjF74X03quA36FCaWyQW1WwFhi/3Tit6d5b6PZYo78mGsvl3Fmt3Z2JFRIyj3d6mO967aKoHSkuwQ4CEZ9acARbQHj924KIP2C7RXHFQEuq5vyKm+TXLX3RH98OAD6BJL5y7WWg0+f9j1zKfRiK2ore3naeyR4Q9cnLg69wZ1JX6ow5vogjVg+9j1cb8HidDi1fRWld7sSi+ll+jFOz/mhvbbtRwljzFhrYkLYFZtygrFsJsUwQJr2gcQe6nsM4QLsPv4G6QuZJWqaD8eh/8IoBPRjU0MkAA5ski4yOXJcdwbTIALfmmTujPJVNHBCxAXexggr7uK4kDG88QDGeReq/f58L/27sXMtmkffNt8E+gxp2aMTGo6ILEq7J+GKsT59Twocib/XEKEUQph9tI64uMrnnnlYPxz/76sQMpE3HxkzypGrYhl7d0W2HivO8Ncorl8uKsl+zdSNTkb7QCKIHCVrLnhedeBIwqHmVK+HEU3ACQqjPOQps6xrNpjnetVP8E/ysJyTKdLlqhjKLKiW3wSyNpcUItoya4uuqVoYp09xnZNlV/IcHoYHfOF2w5JhK3m5bQSy/plnmkMSP/j3TH5Io95cAvU3vCQfsDI2l8AB1Ypg6AHCWWFJ/RDeHzCiJ9iIfk1HpZybRw/34FEqajJtGMM0tKnA0rIfXx3+yKRAhwrpNMsxmkwC4krQPFdPVn/fs6qvbZtPhozcl82wfjiXGk6k0PJg48cTw9G/+9Hl9ic0LnEG742rYwi7u+4EeciTVR7RdcJ7AYqlFcaUb9upJmlHVpt4jsNCJ42m7hVXRqM7ESRUj9OxBhkD3y9OMxPvD57qKE7eLJMpxFzznO2SPqOyvkLznSijSQltiihEAtT3wsl9YmE1ycovpcNdQQKvYoXH8TW7iN7VCLArEfJYDbq4h5hQC1rSC7Q/ir0OCoKHxwIEwRxPct637Fh4dj6pHHDed7nP14ZvLHaTQYpYLYkoRxcEqUEC70nvkL1gLFh+k+bKl4FO9yWGnUjFEi1i4h8dLM9/wKXI5r7Sf+dS2Q1jNUg1VjQfgzzUBfkSpsuujTUDWEDf3mCOhnniBLgv4miHwudeLBx+B4TLKcDs7EZrvNJs8m/b6Vc7reUYU4bJlFkBdqVYPSHPzm7V3q9kLvhXKFxllKzKYf/kMLhl02w5boJ9722186Oc1cE1f/CQGup2Ejo/UOP0TuVnsNrtoq8Sw44Movh6AcuvKTl43GpA6mM3hn/CgceFkcBFu+uwygQe0y8zqyu7taEoio7NS/k5G2mqXBYrdz65G7EqNyrcMNpPW/oXAJUrV/hzZGnFh2rshzlg9vHo4nEsPG0VmrEpbF18sAtyEaAe+4+d4lXdQnGa4YwRleBhNbR/ttroVy79D2hMHegzqEZMl8XvZWrxHps9h8pcJFm6iYHC6FFA6brjr9UnfoVnMj3l3XtenCVD9exnPNXtd1CAJIQHJENAyXg27Vq5aGt8rPQCguewgETVbMr5svlzcEPYLFLwmH6Otj3bxYQJphAh5nzi1XVKwxQcCu7zJUYMTSdPjRFUUE5Gox6j67bLkqBgcg9Kl0uEbS77072G8a2UoP0GbEUmnQYibuGrgHReeodv83MclcjIT3ANGLB9QXJzOxJOFCKzUjbYUtQhVFofIXqs7IuMxucTHuvb8vN9p/B4otVkIZ9ROCXueeSFYaZdynT8MEYBV6lUbRSWIQgxjXnQM5vV9bmT7CqTg2i8YW5+sgv7X8hM6c4dXBEIns1sEldupFU0u5sKeO39d6kl1nYQ6Oj41yw/dyTZn5+SNbWfUZDn3wh4BKxK8IMWKEhqRjGnb1r6NdK8FC1FDJqczbEG4RIzlojt0ZPOQgUmbvvb1TIDBBbpwNo4l6aPuiUhaTp+qvESUDcILZcGXMD4n8kCtdGKc7Yw7sfIfuXQU+4xrnhgKc33FVYx8+DacNn98v6X1WxIII8fKy7GqWXG4hP/LB8EeNkq7mB9wmdWoLZLIPWBikCQV34e3rUsH0ktuaadZX2WHxW43TdqtQsy+KiN8yXYQlf0lRyApLx2/OplXvFB0tuw4B+9MKXUK/QMUdDGTR4/n8AIPxO01sHW6W93itK9jih23woJtrru93hy9DWKgPP2CdxZX2PKIfI6Uho2zQPRHzbjkade0y0owvDfW/0g88MykM5jrSJq/FZ4g9PGxYgHicrl8dGaDZ/jme0pFxwsI16dkCRn6Y1hOSgwQXAf0GPJOLF9lGrx3wgJERxglF2maiksGM+A9UJIUi08VjV85lTxZ5DXt/1cDB8NjcG++3Xb5AChmf8QNfYBNhhPjsilBWRsvIo411D9RrO4Kp6roQzl5sdOcugqsZaXlWIoGt7VAz+cFMTDnLQ+EnU4s0p6b+YNiznIr+623PxkjBrLE5RrbkJIunJYv/tSOz/3t7GnN72jgUCiGYfOOwVGrUonxDPGemizGOcEIDWZ6+R/l87Tw97rDCsaHibQltxq1NZhdp7SQCrpa93NQUq2ovNNUP+d0DgsoSUsFNRz2nOfSOo3mwbf6w9Ji3v0mT/Jk+QcAusMWz+BgArwuIJRFla0E9C+lNY6ExyCFykWe6lQ4RNetEl5g3PRN8AGYsTQCQJhLMpyqQ3CGMr6cLHRWptPC4BKggFZeP51K68s5oO50iUh4KeyUpOVQONnqsD86JXSpSBNg8nsrQcLLdEG2P4BpWtgcixXaXbm39uwVGorxHHgRL+ynb415ieUEXydB8JdEsAqxKJjoWHeQJhB1q9AFZpIjsbcpXTDDL1h3sVTDL9/ZzQwRjlTxA3DKMyRbR2Yu/jgwlOaiaZURtefvakb6HdO2aALX3pqHUTiw1SwE5+lzblszeQMx/sh56KydXbcjmTqEjtXCFZ2IBOg0bdTfxVpi8/iT4hEcvezGIpIzZpcbQIdGTjsHeFjFlzFXsujj9l8kz5DZQTodY8HGJ1lZxk31rwl77oFP06FtyUPG8Rz9oJmjv1DUb+paYyZ+IaHOA5EfM5S70UfJSpSVHFgc3de8UTgM9Q1Upo7A1djFNNPnOGXeQ1Qo6+pF9Dksxz8Lk8kk3oK/3JU21EwDsII8EdgJdzYjuQ6On8K+yxGPdTJVBPUtcyRJHoKoYF2vX96D9XR9qM02qf7nvUibkBmBnh0fhOCXo47HBD3yQYCKvaHOmxndUeVcmFYbcESF+AfvSi47Bg/KjpMh+nLv9en0f8XZiesDRJPY85qcHn1eQ/3fTYcJGd+Y2+RW02h1AveeK85Axz/K2Cg/AEgxuUFJf58vtRpWODm7sg8A3UTQaD4ymT+ZiserDppSA71g9DT/WDAoQ+/2b6fBFtZg+oes32OUt1cVLZRcOl5SWicpoiEemKwId81OR9pO8lsRB0F3T5EOXa+zFAwqtvO3HwH8HRwaWJxLF6qOd2x4u7/dsVBEbkN9I/t5gX72MQkRAE3LA27LfoAGevYj4mrLHJfddve+VXEGQhBlFzjme+LGBq11DWxgf0CUVHr6qA0gEWyQQjvBFncQ3zZjtZNaXVpcYpsL6zTDZXONXc6wKmcd0o5X4YZ2ixSfOXkpFkU/uIZrzCnWPHBkXB0pRwFYyPuDki2YiYHbDDIcjHrA3DmvFfDfYf5X9M7P9ZJdjZ2uhu/RQLSDtycs+lsN3QsKtqPa1nI53sgvaln0ZeXAq4zvfbJz2cz+WbJXMzK+L/bKkGRemwQrOOUWvTkY6YYpr6t0YJ3Ksa9nhLqc/0EO0IBaMhbkSxwdBMizHvXtsxML4d2VdEp5K6gIrw3vlD5PG0jEGl+QW4LuH1Qo0ER8ZO8lG5hhiZdZKzt6XSMm6CsDtvQmHvWk+2vcCikGhmdbO9+3t7BdH53Q1W3FgYFpZwxdH4PwbGdSbL+G8j/W0VPRZnFOwMwZcXZFjcNRpTWxOT4ZpnzKpqlqMwWUQplXsWZDUo+ZeHl7EQHdqhetpfgwbA4sfeiIZrJHydj0OhpFdQiue+OQs2rTb18Z3l6oR+04yh/KqwctRAjHvxges58i0bBTWhLYqv/bOav6dOMyTyzzqDqfSoDl0XmCJ2gAgfY6EpvpVxZmv9Mve9zKgZ0aKAW3DUavJSg+m3if+kC1AGfLy8oH06EOGBWJ0KcWA/R02nEvxFQ8Bwub1X6n8PpySCbgFUON4OU2v5c6XxfrGR9na7W/atfdyPhV3lDT2HveARlHIUYPqp+6s+5nDX4se9JWNHknTK0ffN8XMZHCK89rfUV637uq1/fnAcCl4w8yTE/EQ3akAtA22ApwwAsX1hG+TXL6YUuCtFicyVGIUsU1bkBC3kmXUkO+ATLzBpy9FcCW4qRA7RgtsW/f3JShRBvParvnPHp2PiRsVyku7/LOLb8NghlR6AcXhJ3agnqG9Rz0AeWYEL394gHkjEFsFmNDpUNCsqvE6jiic2roojHHwbs3rUyMLoMH6c5C6XNXRreHemuxFoB1oa3NW6ltmCxc6ygGH0kes0d1G9sEOXWMsv2wyDdQSg7ZBHGOzttzlnsufThZID9lGygE6GwUGxJe+A6vBZO20QrJZNfRSX/ZzL6QZBKHvSoU2lpikasP6rpQ5E6et4NTdu5OKDxvXWRRDwPXJcaQDtYf42FnSLNFi2i8+V2wsLnS4UuOR7g+Eebd37ApyP6waG1ACycomMPnrwgyiJzAUvSODGVVGHjX7aM8YGv80sS56uaBFTSdE8xVdsXtyeb74y6DiEf9UzhJZhrSErdkUTLPcTz5ozSuzoDB+ZDb5hS9tm+CPwcTFv/1LZIAayDJFaEhOfj1wwYzYEDpiqUHIqnWlh68CSh2lkR58WETG2JWcRG38ek6BuWQSFQIYjDbQ7e09Dg0fXFdC4rCaf0IjxTt10GWJCcZaDW16ADIMPmbPeIiAP8EaHfqwsRMnwghFrBOIc8EaOqEy2vnjjGIzC1EdANw4Y5uc1Doh4gyJayomXGH5TfQan7OzRLPzSNLhQTLt3kyh5alEhsoERzXvD3y4qIo+ej0XKWv/JqwnylPrrfHaueUHHKguPIq7RapY0PkxadMqrd9qXQ2zhR/19PzTioavSF5xc2BrmE3LVDEvo2Zy+hl0X6CTcGKYWDSVq4ceoRD52er/rfw3IDgC7b8Iea54e6t4MN0Iuz1AMpGXdpgY29WKBWxfKOaXeViSWUZm5TP8U1mrHkXyyIfuLVsWRnOJqmiVHgqhTj3T9LTpdBkdIiLANmAEgnM/zmliavCx8Ydj5ctV2KS5TnMonO9NNi3TtF9dc4CfSkg0vk3b5BA0glxgbnwrSQEU47ID//fa8/oukpwDBCrIoAS1k++w4KZKun7/1GMaZ7hcCZtD1FPIkfmbvtEXINL+H84kewlVvzaZH51eM2IMURaHCMKrX2frqKDjODkiFRzeynpNMjijqaLmtfoL7ZFEIyiUqy0pensAd4biFaAx17fIK4MThcXQgE4RipjxvI0P6Lm8qSDltt7BA/u5eKmSksEQNF8ewBeGmgELo0WYA0RUwa+kbM2mbmHfkM83Q7OyliY5w5yKoHLCxIA7orgnipSCo3LXWpQhbXmYLKjyFdJtItveqlRGyJ/ps9pHld8gf/Qn2Q4w0RDwLrfyf38FZuEBReMz62wkWdaiSOXbDXbSz/hPg/4HXi/2DeiYCg3qNleFvrY0wj/WM6m9CPg0wB2BNp99u/BbBzEwE1wC0APzD4eFrD/nxVbQQ0LirnbU3F1EeDn+t91nIc/sqeAUqllJUbAvSNwARL83j1Jetpzobc43HQDhU6/QtiSzfQhm/HhQi/PhIFhkFtVqO26ze4vtMg4rjXX2Q0Vhy5kWAnsJ6ubpiT7wNAUQQyiWQL8c8T0FFejjo5JV4wkPeAYS+RtWBRwTMeVf9wkGFZZmXMOBvI6+SH6HE0zgt1vIpgA0cyI9t4NAakJuqvfwwW8OGApOuJNEbz+Qz3x5OjIZP7qII/yxhNoLT5N5pH48KKrIhFS5mFny5eIQNK1F2WZOzMg1mCBF4JOw0YE9htuPb6olMxfTF15/83syr5WutqE8PJPRoknuxE2jAH4n5YrE7A19Qpg5LkSWd+EP477jXX4tg5QPQuZO2TSA/OWRqqcVSi6rVZ678nThDjkqdz9KvW7dfBfOSY6NlNKEZwBuwpMxhlsaXB3qxprzwqlgWcG5H6o+hRL5tAMrbbPHQh5A5uD5Fd0RV8e7tNukzcNkVs93SLyESQxzORqJZZNOQIJ6dzdBuERNKWpleMLJpPbXreVW7uoTJBQ/pIZOB4Fto20egtTQr8qHuC3GOr0N23LgT7aNh6irgodEit75RSTcPqiFlWbIgv/RudkHvS27FVV+q9YQb+hgtI+ZkkWnY+nZDz6U8Xtphtva0hvqzdFrPxtw6yll5EzeY2WMe20PQSomAqiK2UrpNXRBM1jHB+LOGO4cmNPWkCDIv0yHSoZZ+41oNTTWJkTFBrTxOzYYAk1q+BSqFO9gQ9JYDkhrPDsTYwUh7AJrmLJnNcswifQenEve417y5tPZ1U7pFHULB+iJkam2M1+fqPwuueg2EfJMlTYU+bM8izpQ9MCUSGK5N08i+BifJ9tW15qmfluwHO+KE/1Cd29PPbdaWnOeHdExVG9OMaDqcJX+EIB+bJQW/yILkhyjNMVzitLiqch2eb3hRxtuMIu8xPlPGUa3nnHD4Yq0Yy3RPHawNzd2XASStvXUBIOr31TnVvRW4DMxPSPjx9783fiONjGr2EfGoCR81a0i54NwvNc20o5sN9ltxx4NtXHBOWGeG8feJTEXuqnwmNWGam59wHG4YRjPVx6dvQWbvgKxCGj/87+ysi143H7aBsENgfNvh260V/+oM9n22oxlCostqX3tC4EHhPwMj1NCnz9d0vGIdZIS4e11dgF38/qxv6xuEDPVXMrFgQ78tjOysvEiSL9u1oMysEKAzDPhVgdWkcO7MNQm3apcow/oStuNpmlYY2iKP6cG+RT7PrixNNkHHtUBe689PU0LVkiUpMCL3mX7t5zfq0vrsWeY60RJRbnbi1Tbg7OnPjc6RMNxbE0r4ByMV7ALRQcxNry3MZ+VnH/CQY1MuoIT49TIA0K+FfneZTd54iEE+Aql6cEfV40tgvLz9ABPZ//zFprSxJzEkpyONvs7GPYgwaFx5hzrm9W5O+I4J12Im2juMULXHIoi+7hrLq90kSzceJ3TjCHdYMnr3/QiRqHEafiabqca2VSlh189zDPNU9Ua5RGXDDBLGF3Zi7/ZuVEMBpjJryuNpfw3ZhD22i04oNY3qp/rKMb/QWsE1xh42DlRlanXd+jdCgrG3MkfSO6kxASh71hD0cZir5k/E6FCv01ZRAPO+QpOKl9ymqgPkouUtRVauItyeS+blEPDdzG6lxsSamTnZvwXM/t/a4OZaYB956KgtETEvO/zFGWUy41eXwlna41oOcBqqZ1jqjNi2AooALqSh8Ri98enPPnDJ/kYdjJLxVwto93/BOFYhJBtg3dBoOQSvM17RCPuNCW3+u7/mIDCjajRGV8IF1iWaV51oVrvUF+6O6BMJQCgxGuQS+5pkqe+kiRoZzeU2914sz5bOXB2xhdYttj8inj5lbtc4zGOfRUXOfsCUftwjGluBnzx7x3eRzPqCf9mPTWY/A3KwL3/txv4tmLqpZ3h4peUCwclvg1CZRSjsv5FBg6GAhhkDVE742+j+hpJ1lshPB7xrLS/iUSpKeuX1YxF/X+QTLKrirb4keD2ev2iQmq3MQT2XB6r88+R872eynldhAAcsfzBhAIZDwbZ5NqQHE0oh+CDHRQYsyI8cPABICSSEti+OVxiGGAC8ds7oFTEqKluVsHhu56yu6oKPNyGvz2ar28B2tC3CXq812S1YSpSpg3l8Cm3HgK6iv1sn2VfEEXXFlU1T8BDuaL111GuNADXrifU2pGdDrtcIq5leA1ES3Xte909sblyQIybyC2pMSb9iqmGqFDCgOH1OVwv5NWE5wJ5+aOcaF7ToRrgnHzjrcU04HjBNt0MG9ZXWmq1+qO2+MEJIdfiwRyYxVG+BC7n65Hx8O3BpujBHQEQ1wWJSHb+ph90Hkpay2rzflqRYbYw1FGrbVxQZxp/wtErseaIbU2mJgoPD/cKwZdzj1dickamipkyx0vWqFR9vkG6s85OydSxZnubTQmi0nCU/zf+KtfJsJhpcC83ATyB3nRQhiXrMRKyrbs+De8NXMlam+j0h0bvaztF1eKnFaBHgX6T4ajimNmQzsw4Xyua4B67A45Jo1+7mphb2WkEJMJ4i9bDfD3H7KBN96318mmzVwcG87aCpufXuZrIrD7xfOlu/nfCHYqBpCwjHL8IHs7QJqVQ34oV6QEZJuPkVLtxaUyQvxX8u5rV1PBZIc77+K3gebgbXQAuZuiliFJbCiQ8GOeXXgU/RuI0Tp0wdoWDfIkgMpxyZ/udvkG8k+ZwjBHOOr86QWiwtSj8PUGH3rLtUcWQhqF8f5r/MD+5xHzrk9kll8tddlRCzE7M/YmWertF6Camprbg90H3HatRVveFGk0rjgTi6IGh1xftmOxpNf2sUlTcdx7RMjv+4TgjuOEkzGmgAiwAngZCz0aqBUpmMatsA+qPWV1N80/9iox1NqIJ/8lzq82RVizMK5MTJ6YNMhMdr0HAFiV2gw5AqjA88Mr+W26kU9ZjcsfA8qVw3xKXIFTOBUdx7PRMYwlSDCKkmxty0slwi/emDAA5M0P5LZ0MofQWGIUhBekOkMf/cajzmGJ6qxUxwSpgE46c4wrgkV+sYsRwUVzDNqUSxkBQth/9TD5Yi/ZesWvHmI/2hwEaRF+BGwA3pKUXapoX+rm4D47OI3H7Mg8+wDtO163YJRKc9F33KVKuZ6MLSzNSPgIGnpO4aVq+W+Lkr8IE5dMAEvcSTiDGJDeB5TS2rgfAXOhsczLkVxU8nQ1qLRStyq/ThZa8M8Pg+24tqusjhShFh1a4PIalz7lQxsh/99Wd3E618rYUQLB/MpP0BumezX0aGJzKzWY9m9Y/xgqyP8U5CQ8pJo08jlg3A3XpE+dzOO/sb5/bpCSNlvNvGjbT/sox3niN5lNIgmeqvbgOuMmg2iPEdPrO9u24BKbrUubIwPul++bcKwdWu+vfHRkKVMt4iAAJ2vkZXAvQhxd/f/hf/uEazOhFjVtdCgTOIdD2A2f/n29CGGKWX6pfHZQFBnDLfk3/p3N0TEIVWWpUSgU9W1KKP8KwS/l1y/SHlEY2tyN5D06n6b42U253ZsEWzLKr7piZTWWYnOJBAXwZ7M+OKlF4x5Yta3jzYg1z/EYoEE0+R8HgT5app27mIgZ4ixr4Jiv/Pz8hYFZc/CyJCnqF3l/wY2tzggppt4qGqsAvWpTO4YbmhRNPYEW/yp1smKlJHt57ovZo+z3WO8/Q0JY25QvTB3yQcuXCFUnkkSaWHPKi/BSOeQqo3F0CJHIrD9C+90S8zkxBsxpmwZ8hrtM9VZytZahZtT2qbcVTxHrXYOU6GF7geaeCY8NKe5lFFbS3U+wWwkANHb45O1+NHzTysB+Lt0hb/yuWemxjGfJIOuhaORt6/ab9iJvdlE4ZwqN+vpJMRapt4o6Jx20vzj40InMP0spGGNBw5rlq75cRtafP6dVIgqRw+MNt+dvj4twM9MhD/U8a0Ra/hhhv1UwSMOxsq9dW1zUbg7isP+lC8sI04nMLnB0hhOHmZq1aWOQgs5icFf6ZxOQvyUzGr+7xGaLUqWy7YzXBB7BN7QHUUcGc663ohWzZ31Niol6nLt0g2+unhn6OZa6GhJHqY3zBV2r2p+BszVHP2ZNL9W7+tmOQJlebdDDx0mPL42bioY1Knl7e3D4iptydjaRBp/0fnGHlcu1LcEqZfU8NQwLP3zzMoR39atYku+DARpHPr1QBjcLtl/oNWUPccEF7im2U9niq2kQ38F16IRzv0TlYlxvQPMMZGyMu6g52AD8ZrxqVbhr+bm1ys7wek3YB3OtWrrrBOjS7neADhnlP+TNTOLLbN3qnnuZ97O2XJXphn8tgKTSHl+1WHw8EInF1K7QZRftc7wu5vC/CUlGFKcPld1aIvTQlkQOBFpbCqINjISneWKtqMVS96Q8thH4UkGHtZ5dlbXB2X0rZo8NibIrOLAFal74wkIuSh3e0pNMJdPNdikvM942NJs9jCU1vYDaagFEoBfYHfsu9c7ViZANVUTgUMjRS7vrmCI8meACKkvFs+bdr8jmxr7dzFQpsV6Y3uMsBGn8xFNYRfEqaEVAJNZnApWsb+uw3Dj8O87ysasrugz+ReOfkC6L9TGovdAap6DN0qn4+A2iBSVfSJ2zY20kBCwR0FAMpNHKx1mqzM+5ddenkQDS/tNrkrRFvOBSOAfoubcMlih+2n5EvYFhLI8yizPf8EGUlOiQfNeB101uRMaOv/bMseU0ea18ZlY4jA3K9ray7J+l/cH6N1ddxmOHxl/5azBorYJLnq2x5glfIPmjksYnpTQpHoMdB17H9+HuydE6SmDaEX0EXiOAB2k6UWeWmyy9Yfp+btBjkjEBX/J/LcNgMYVk0m6EFP57Uyjv9zaB9HICl550mkC3sPTEW0A+MZiL+DPbGS2tCr1ZZBOphhyxbqipsUA1bVaW32Nf0t2VZTgV5yVP1exODoIGxi76XQROqlQVoovQ9T+VUk39f+ERKI567qcYiUkKjMbD+VEf1+Du4oJTyiR2n57vXBiM+ueN4cCkHYUJ0qsbteJkp+glvhihHHj7qrp0NTCcP2iL6vPuoW/ohCHyUERvXK1WsRdfRWNMdU5zVtmrJ9NtbThZVJfNd8qbVIdbW2qLyCRXVNvdxH9uFrAdwbokyEZZHAG1pZpHkLKUUqRlWqibb5wZM9d+LV8IQ02HQnHy34E/sHcytlcmC/10c1hz1rfxZ8dMWVykWQL8TeVU+MKuP+Pg4Wx+t1y9nKMZTBbWPhClA+yjUkVJ05xeDRMlVCag96CzLGwTGimaTxNzkQttgpxa+DXzJYXDAQApOlMt+TN5WE9R2KvNBCAgBAYCKcbjT8xeCEpVVtUqH24Gask31Z4W83GRjwU6bXDdeNeLKlvcZukBjEC9USBHUEpJl4pfMp2Whl0n7YKrWRzlHgyXy0DJopOoLDwwB9XsbEqc6fReQJRfJ5NYqrxwB+NLJwii0UwC9el/FSejJrplQ6HjwPO5mnaFD/UjxVsrlRWAGjpqsPr4GKhJZa5iLo9+Qw2MJqwpDczqSMrydtKm2s3Tg5nhNMGPFXmDTmQwTPd8CL2/zr13qRHs076bLJXy/HQo/wyLEKqRV+kPRY1Yh07P+Z3QJmzI860LnJSpqr75gBRd8foa9URPcNpm7f7y5zuXssjlyM8NUXazWPEfqFr9Sos4J2uI08kgNiFc4JGcakedSWAyawLF6WDLtxI45xMTU/jSqU2KGZBTesSEX1yL6p9Tjib4XHH9SZWwK+3iuIuU625QAnuWxyFxB/JWSEu231JXDM4QsBkKzovEWxs7M+Az0FeYqcQIna6IbVH84M/y2/o4EomnYEGMs6uxgnM39ySGAXMFL/vqFBrGbcpHOrCJxzeAUiFdv3Kxj5Jm9yl9tXTBjleBiybR9UO14KYBCKxE5mCxbJ59KuMXaGaOEzP32zts79H7CnPbNj/k8YemoZKlVCkGiqrNLvJxadVEJTaR4/92yCPvh/2Cig9ns5UjI/cUsyE14fPRRYPcdinjyqHSLWM3sJXhf/GAjSVJjtFT6jQbsU36mYOqEKOBKffk1u1ff3PG63Cfj8RLNjrAbg1N6Ed2yW2lqdkFn1VovdvZjsA9NzfqW5r8apvzh223WV7Py1mLCHofq0KCwxDRmu01inxG0BWR1keVJ1DtmOTWuhpD9ZipyzU4c0bOhpOsEbzWbxIWFybSMhkB2pNY1EvhpCmUP1U3g1vQCpQ3wdH1BkvJ/795PKS1aBSoxY1nmX/H8N29fvGYFCCmx8g4CJg2pXuDnELGR2jWteBvR0QOBCFPbUj0lxHgu/2SDQyhh3eWq+FVbEccydigHcdglgtZFMvgSDoB7tQlesUQDFP6qmeNHYpJJITj7bG8MzDvAX1LhUdNGMk+nRuUli8C1TOvW/TU357AXvkKUg1+8blcnscz0CFw672TsvMORFp1bDX5Py3lgHJdHgF6GjzZ+H7rHSBQ39Tb17mRZREHyzD4pGaS8JMM9WXXrXsQBY1RyVMGmP8AINs3mwA7oRTIMboEZlzD8T8DeViqjZGeOtkEbS6X0IleUs9NzzBdIwmJa3cZtUUuZBh/eNapGM0U9mMjWH0gbjRDYL8w9Y7fw8TZpIJ7anKEqyS3QqcJyJlxRPT4P/4imp8PKXu2xGZ9KEvtOurgfdfZyHLklfUnDMHGiXLVeSFm3KKL+fWEdLSCBxpM+PHEM8qK2eOX+g4dprcd+BUmpZScf7QPUc5O6JVx3Olvtc7P9IFmf2iGjlY3xnBmjwTNoTCHkIAlgV5MOMqGLdtBZU7dbEh9C/7NX7ZpYfgJbjjPuuwnIFfm+1TQMyb5l/AtbvL0cDDZ4aFKsVRujzZwo7ZHaylzizID6COhw7w78AFn9OEddIF7IDzg58eSpI60pj+PktOcqkLL5aTmYC+xP1U+bFDKs/a+RJsa36/dl/AJpDdUXQHBxwI83FYl5jFJZ+GIe9JQDNZhH9jMT0tKe2k1tIWQ2vMduO4MrWgxcXuDdwHzUr6PmAYyAisLaCLsePAKc7x8pSIrkNMEZRrOKzWBxekUBC1FfrpLQOUC5+g+3S/+3z7XJizd8ApcXaGf+CGVJHkkOfRuzaN/mpkWS1605mDsQiSx9Gkm40oLghZnZgEBFIkcxVTMAx6EcyVHZvvRLom+YHB5eH7bsZL8cjBTOVvwkMFYyjf0GP+AQolyLTGEWXHSHoVdMCqvsDr0bwa8H5TK3yRRFQpfB1iA1BZ6XMAeBI/1oGFVdrZupe6cKAGq6nixFGqNEqbCmjt4B3A3Q50CauPmSDEta2ks+veji5ZmYP3GP+LHE7aQwsVKOx+of3ENnDw9jW+gfOPQLwGUnhuCkk1UHrxRNnpXZXabnLTyxrK/V52bOjAzCoGN2glItlsCEN5GHqK5sTLXmpeLJKAvx0iJIRu8SDSYZLlbYwhcQEdIaVnXmnZOf0aoC11wVf9fLevJxqG/yMJ8qOLYZCfBOvUHz7kvwWheeT7EwIKnszEwkmMMnpDQ5G517IiE+yzmyt2p9Q86MYmW+gojbgZ12sLILD5uRavnv8RAiJF5SbuQlRvVmpYEFU/MW6gDSa1VLPSFAA0VlEfWsv4ESh0vgWVf42qCvnJzK2yqGsLOupRwnjNboRcNVJKdr+tIhP5BE06d5xp6BXXhRw7eQGzpTAGK6/Qypr/x/zSz1PjVm8gR4vaEhguwkf7C9ZeBz9P6A7bXPD4L2Qs/Rs8VnERVKQxUoN/4/KZPNze45T1IFdTFJkWbLO05G44rlnKAaM7W425huQouz2XD0MNbKZN9NqzkkRE4PTQzn3jxpC+bh9nEIzI3Wi/9ZvVLG9IZRVNUD7mRXTjykmYNxUR0a7asIIB1aLzPmkJAekuSBgY6rmHRiq7Y5y/QZtLwaPXlHu3kYHbiJnI7I1HPvaR0vg33NZM2W//dkO8ot9ylSo/q5JtHD0Ql3MSwShT69FoZNPqVxTQIHCVo37YMa0f0uzXw8QyuYxfQb+qXvdCv2an+oIxfqIJZvduTDkbgoHV2qsr64thOqIJLzDnNoQuOvT2LYVPIqDKpXj0nXYrmofHBwFZWNeuvY1mUST/PHS2KeqOaGeoXIlZfQgUre+Q79SDT0WQLTVaUUsdTpTIZmcU9V97CWs3GL+m28HGT4nC1CYaRYMXbxUpUrB0QoCw5Fq5OyhqWVSZw/RdkIAkySQFazQ9Y5Pb9bd0o6Tcof5HMT9ZRB3tIxHokWnlQtUoi3v4hIuON1etCuwxMKzEaYKj5p6nzniI2LJJYuYJuvp23BkQ0R68ZZ9l7KrZzeLnqcUYe6oFuFLNPwWeNdmMeoJBphZFXmh1HNZWcTRLzf+hviaDoODkTRoqtrVQ+PGAYJuUbjErkhjeDvHAtW6U0cotl6DdkUKJSuMeA4p3b3EzpUPJODzljTKFewk4WgjQI9TAFfFxOjH0NXVaWwb83CdO//7rskWiyawg2OhhZBxpcI3hVTHZrk8Y0SKkQPfOgurHGVjgLkPKiGolW6ltMYvF+fv89RRhUkqVFDZXRbeo4Cc2hDNZWYnGInfJEFufYvV2rbKz9OXxsR7d+O3/shIX0FKq8yXjY9rCF4oXMH0qW+vTh6v3QS4bJunsmpPFUmv/urxwJRQaNL+flz9VGkHWsnX/ztvFzTa0JKodO9xINK823OyLK23eDv8a7r6ok4aVPgYBa3UlxMuUV8ODF/H5iN2fFyVlNFFXD6QtIFUqpjn123CBKO3xIsLpsVZXRct94axnGeyu/vStuIExu55tS3Xihx9fR2x/5kIF3mvmedHZe+YJWnNvo4m1BgpOKjK3iqWMMq+eyyUSaKyCkjvkNqoBZAZQ7xcLzoH4kGuIb/DQLmHWDPeEheLpTLPmPxoj+YcZeSHUhj8Cg1wXrJbicaERk39SAElX4AFPTgPjtjelS39o0v2OJBMvS9QKAniSblbqRLG7Wbu3qFb9MslzK2sR+gNpGl/E/I6bEES//lk6KnJORfQP+YwW+dvld29O8ZNRirrLGOhLGjHmklg23fzjZQDQzwTePcmmbnwCG9S9PnnC/LiCARwjw+47A8anq/IROV4GUo+0B2C7IWvaXeqX/lxb9DOlMcy8SUDW3nj3MXj1sZdp1SncH3ijtYd/gF8KauUE5p2ilptPQ/3R0tf5NOLCiZK2cKj9msa7Q4xZLTr8l2snI0+HwAyfONi/N2AZwi2k0xi1/1Sq6fSogcsUOidr8DnSUEHtSMCYix3G2ee0QaJm5oBrk0eQ+3haT3WlTx5MlYiwpGTA47mD39ak4LpfjlYj1aSIsEAvdGX30z6guzwIDWNPlC3BagE4nYEFKuU+ncHEO8kwe0PYEME7p2OcCqelqiif0fV27nvf3YQQ+Q1Ete+k5YpS0QdJz3+5jawZZtcFo9m0LJWo7cLIrRg1LF+4A6+M0OuuA5JWWwK3kar7YKLtG/93gjCvPpMWnvpcQlr+fxbT1/Kyo8ZWbB7z/spgo5wtZMs03gj3hEu/01toGTt/CMOBAtEZ+TPORZN/zaQJMaXPwLkSwga5n41NfgJrWj8UZsFqnoo37jh+6qfP93YpSAgc6LKYhHhYla4KIgPVdkgnqTa2ACD/1DeMQiclf+WEl4ciUGyyc274kd3IC6ayAPwcDWX+8jKEjmtkYS3E1PpDUoIZ+3UXKR4hg8JeRsjXZ546JvdFU1kpfodZdA1eAuYKgXsZa0Ni/o7vU0BCpIzVFx2JG4b+woDxYTvwW0xZbQWIkAlzyMLbBgM6iSbnVFDq3yI6Xc2LeomA5sg/ab9OP9kk72fE6ttT9dydiFHZbNEth+13kwJTJU/t1oKx91XYqHzo8csPVBNz3c0gVqSmU7xnvAr54BBCGEofx5jegYVWemuXWxEizyzDyhEN7VAwYpNMUIqBBTmp9xSnviivm0OGomh8u2Ax1EHp70mDmYUG4EjvYRa5cCdiSGiD0JTndWiYJpwD9rlmEhe51itwCrfoKKdFJRjQ8tPuSpKgqPSgfsRBNHGKdJL6NgQ31IAOpr2u0+TMnKKvEhvT+gbjN/9sc6YRUvnJcIFWQK2X3EJFhGdD/E1crRM6hAl76GcsOU3/PoNJnMBOJ158ihweupeZqk+ZzLoPkK/bUWrRgKmdZH/msADmKgnCJFethlU6NYIsVufPia3OhSgIx22o9tZgYFUf6Y9biHay1Tcle66ZaPHRFYl5vvyWhMQRuK7yXhKg2t6Hm6zQHEFSQbHGWv5bKalof3j0DDi2AxNMH32B8aUDYyJfBZI3VGNh7CHcFku/a7YzHyqP6NlBPsVNUcJTmrT242qgCP/WGsF+K6K1eX9v4EroZdjaG2PYHzbmwf8o49ANlGuiUM6tyWYKl63Qm2lVNJneWm/TzzOzB5xswIMP/bd0vw8DhYDzK985VWFn977QlTaxoI58URpSqm+G2rwhCvWDy1nY4gmo+nPp5xkhahnVUmdfMejbgrH5Wl/t7ZhHwcZ8HJtg8AwvPZYLaro5xtuqAOaqfR7fubfCePYCq9efmFZWGwKni3uRKNa1gi+sBVhTNHz5yZL0wNz4J6T8lI8vB09uODb9aFvJqRfviIfST+L2C/6ABK2a26cLE7p8qR9xNwDkoLGLGx7ng5Hl/N7FKS6UP+M3O6giJlrfwnv3GKmSGh+cd02GrmZIVzxIwuVM/YiXUyitR7lgSYEaN3PTQPtnDxBg/jd0FugOV9XbQXitbH51apwp8tVdNGPs5fu4XEbeUBjRJShNX7Ee9uJWGLBC+6mvzJ2GJA3iUZJOojxlMjzpwR7J+QWHiXbGetC9epTbJDL9k6BWZ/ownKiYDl+MNzTRJx+odmOuymnN8LYdvyvsK0FXNjwKKVRkK3rZR1tlE43WDMxsJ/SUirfVWTphM1zRRAyKGjNi719ULha0VZiC4QtVBsHItu+DM6CaTcABxqY0DBnNF1YvE32UxMDg2u9Rk7RfGBT5xK+S6ZhQvhzYy+aPDca8vf2b7xMDWsWttMoIQn8QYLZ3depJ9oJNobztesA7FwHPcL/nxo/H1Rsix31RBDJlZ/R4ZMl3PO/0sIKySo1an8lbLbMSRecK4djdtS50BlmhHedJdwGjo7VCYNGl7ypp4RxcEPTXeGe5e+vWO91MJWu5pZOqXENzDg35YFPzXE3maNI+ryGWVBja1OHNzXj3BrrSDoLB3Z9tHvGYsUVKdUie6iZhernaGd6txGizRQkCB+nG6qJ54FpapSiRPjf4+dg7ZzTg309NE7A+vZ/OgCpdHPDgvO0q7hLJF7gnanJ9WK4H4tunYyrTTIQFioFdr9Rdq/5GtL1E3t3VUEtiQgAoxhOHOK+h559JgtgaGaViY5xz88E9XHcq/PdWiJtHH6fohaz3eS6aiNwdEXf+4PBtMOFAcn4Z/bUtgL3ApcBy8gNGKYEtWC4iBHGiiYmnUn1dvLR2bG+bYLo+FvwlbON9NLivaoF/SbVE7lvFnjStrpNcLLzysFjLaEdXCJ7ap/ZWkWnUpKFAnmEkmykXn5HoWs+dCsx0rokEazSTkT/5bxYWXAyFpTETZ8WZulbdKmxVBkn0TjBGKwawP580OyKl6RlBphDB5xg0DWXDf9oQHUzu5JJPp2V082AU8EbiDk4AjP6XdmCRMApvwOOpSfPCJSCz/+s2/wabVeJBUPLDaszS6Ai5DT7pqQGNzH3U1aFdvkAbfEgcCx2Z95DcP/QRSamvv0iL1RQ0X53eklggUCi9syYQDChzHSFSsC43Ns/IJLwXPUUZQM45AK1jn9z9e9uGoeuLJ0loI0ol8gW8BsQ7rCJXtDNLbrDimmVYsH81CiLahjj/MbXttpLjaf73G32jCVkHD33nk/UyotTKg2SySSTt545a4n/WsqPSt54pI3awkMgZApXfgsOy3I4p4DSX96zwqCKz5uwlD9fIY+CK6K0FbvVzWZZ13AHHvaI4YHWRaX73T+jCKfF3YzTc2K9LlJRKpriIP/Jv1w5sNu0CUu/q1lfrA4AbjUHCeF5NmBLk67IckwD7guqpVjjIPgHFcwhR9SOToazmMb4kbH2cXAaoZdOEgVP5t6qvhYgqjHDW2CG74OshdoP6pSIIsgwBABqtOWcRDjB6I6XIG9g/H1Uck4/v19EZ1wknJdGlcBaQOaEC0R+fdE4nsp67GHL7GNrZMwOeoEOdlxk0qaHDOTjSqT1NsRERKBcAQjRBStpJmKsM9fsw0gSGyJOhExovWbKtvy5ssg+eONwSF8FGXwdjkp06zG83F9sGkQ2t8cOpvNgbbb/GR0UUNjXJAv2MfKXf+T4SK8PUMd5m41F+EJ85rORbnA58IBkgwqgO9S1dl1ZbX2mYmlrqtdhpo4R+QwLGnH6iCLO6O3mDc5JEorrcvwMoMFZ05RYE3a4GGKR0mwQUGuh9pQ0nhC6NsRhyz23Yt0abTrnumWw50ajWSYLJ5zGfobVsZCuQoK6s0fucRP8uW5GKHPqD7tOtZvWCnfQ4DPWHZIocT3vyBqMUNQq1I1zz1ej2HnASTbUWLIsMnQg3L9fTbJC7BjCERzj/hKqkqwPYaSqWXV5dyj9hrCHisRhGsYr1yX1UdHjbqMsVpJ9pWGjkLTFnMJ4YSAI0Mme2uxrK9ZYklXX/Y0ZdTOObQGTTLqvsqmrbYZNjSGKVJkncl4DaD7jo9rV3qQwSEq0AcSvPwVocYHTnQ5fJt9gIak2Tn8+3EuO7ICP/398dPQfUDzljFQ5VZlayvOd9HRhok/dQyvVVnfSmv+iw4yMaM/7hlf+t8/ToHWu9JUo0TNbdrxW4f6IEKfZl7/EhYfMY5UN55G75gbLGqnEbjI26u/ygBYGAumujHRnxkazxAsBauC/eMY+k1b2ryL6WDOHHd2rvVNV5TSXUlqJI9a28v2ynkl1FABsBEBF8+WMgvPOLgSTbxofPmuacf0Z6LcQireFy94BNNcf4YDiA2k3NGnLYc8y95a3vrGymyLrk6+gG5mbps5HXbHd5Nizj5sOcGqewUXUbuKcbxuHq+sKgcMjt/js5+wmx1FMdVcGkJW0iOplUBluh0BHWlzfPVIHrUA9TIrwnOrA429QC2cgOW4pcmEG0V0Tty3KkpZlL8+FcarQGnX4+Td4hUpNP3hG0o7OT9GVX29m7PQty3ygnKhmB3/R4xpZ0FMFC+L6QgNmSVn8aBTyoOPW53KC8D3HGeuB4GnCaLwxxFhhm3ydIqXM/FNjvGBKFZZbu/ZmmruntHiviRuACBLWcXhtOAd4hFbbS4yL0+asx1WJcp/L6uVUTTcInLqw3K5z/ng+jlnK8K/Tdga/ztELc+oQDxqoJBcbbdJvQ0M9OfRSA58NF7B+bc2CcXkbjorwRSeIsegiuD2A5W/f6KeauBcttXwg1sGXSxAGQjMYfqt9FcdthFVfVV/rWL6R5Tgy2rpBpaDibMSgwrFWCc5b0M9j5qzQWAQRSeMumnOqR4CNsV3FihbxwGsvs0RSV9HF2YBTYX4owSNJ8MNI6uTG0VJtoSkmoPjDV2iTJ+gXIJ6Xb/Wo0qTcKlkqw6UApviDc+RZ+jjCkdLRrjUaTF090dF3InuJIkevZkA1SAC+2A+BgjhhMkn3e1fkeO3M9E0AVWcNVtCU06ITkhs/yV+vZgxe1iua/aYxasceuQau5s2ljH03OJuNgklc1tN/4zRmvASFmv0fiSuEw6xLIvM6cYJr4TpHtuIP2T2wkIFImcI3XX1JhxqmBigAwYflA8wfi2VpJtzPShyNhD7e4/IXmK/8iEDbXzZvEi3IZUttv2XA4+VdPku4S4JlQNjCJjjwz005ZKbGVc5nQ1WJevw7rLZuHVKcLMJ7f5akxNW4Zk3lmwYZioRmOFQiwk7MmyRxQd5YFtw1iFyh01z4yqWYMvIdCkUzLhxUn33n2RQ5+jA7EJaguhvCKyi8EZf66y3yzR4oPRl0bXwX798/lCI9Ns7l42MVLXDBuEpQzZqcKEcdcVqbT2Y5Lxd4vDYDZ+mMkFi2ZUEsn9pv2Rv3RSfcVJ8zgnrUr5OI7Iu5DPANiXdvvuLRKgftySkogNxLs5kIVgLJ92NT2vtzfd6KQLNz7iqu57wdidzgmRPx/uTZnJ51tPa5xqREwctPqg3OmAB3XLnyGOiO/YAvRbvBPKOLtaeftgOGuavwT1GPaWdVI5vflcwshGvO58CwnXwK7GzbsfGaq2+xNhiYuzmRFfA7EED72aSZxKnesSeMojv6fQAvYE5EVgmAN4An7dkg5JXKa18Id5/wvy/+uLD/R5RQfN681tmvx8nguJ+7+MiUw+mYTfnnIoD8e0Onhovn08yv1A5DQOrr4cIjdUYzjfUabf3V7hjI7+BIlkXvM5Mrijs0cBJAaS0FWvgOt+4kNqyLqVAaeilUVW2gSrltiATif0cFvmdgHBUss6YJKtqBKmIknQiek70WXcKwqo277Tqxi9GuQWdf3gBLrYsEYRO0Z/SbwIN/mRUoAC1NeTZUZnGLwnWFKPbTsVYgpWxWjo4LhCNuyflPuDkj7WsVG+yFyZHCmajpXeg8DlZ2jfnUPYdrj0mywOUYOlZEYthvoTxWpgLgv7FUo4frT9Hj20XKEsb8w5vVF2QMoiH3aNfQwrIUkhuVbUij/Ek4O458WVAJusTHqx+f+JpoNJzJ5GlsRAfW+vJQid3ZRv7HSioc/MjZ0Q9iCxBo6OBpCxaUIB8f2RplaGIH1sPv7F8zMF4+Jqm99nI277aEJ5umafTx8HkdNwRf5DAVQM90P4nYHoI2sGYAC8G23yOIB8N3uiMVT38xGq2Cze6SBqlypxVsRqzq4mjncm8JFjZEf9u1JDIHTpss0WqPD3Khl502YWUHWucIAvpKSZi8YnH6+Iag/wimBPVDZCiEsC4Yq2KQ7rfBTJ1SAjrkQ8LxlyDp7nPOsGkrbgX2yFXPx9a+WwTvZ9j1QjbQ5Z5MAl7ae3QgCyFzsEvXnyZSdxlI/JjkVUrm4G+bf7QvSCTqhrntPsIfh2+FfpG3ZNxqgk3BQU8dWGYbCGpm136kUMx6yRKTzI1Hy9DilRiAlp0JFVVjuSBBYSzkp4HaEA3A8WDjZI6ZhfWWk7GHg1x3r3WZOLCBS7Wy4eawEfGqNWS8E1d5tEVnpsqQXo7itTUvnWXNGpxrLDohAjOqITVBQ47JsXpsAo7DGoOlxMlJYTPiG1PbJ3MZZjMiN/xJMUFu0u3Vqs2EW5f81jF7fLQun5NeDwqzZAVr4oUD2OfoOTqjqFRMXL+geOTPyyn+pfv4ZtA/e4tbpL6bsVRIvFaEnrF9Q9+hZ/R3jUTScBGPGh5joFqT3o+okPrZw/W4Sr3bbXZXOWf0dvnnLM6MsV0J189abKUNcQ9YEL2UDLpQGi0k73EpsJyWujnGmeAiTo1BXppgYeGpHV8+F1ulTA/+gYPulUp5l616/rVrg0awRoaeZMgUx3Veim/fviJVb28pKmTOf+taf8XUkZpFjhfv5USkWOBnyZgxM0nBb7tkrYGF/Mz3D2j9rm4FwR8Mu2zjRtgYTE5ts6qJavO82nw78LbuzsjcvsT0yBWpZqaabJe7+ydkHMMgXaB1LVFkPreqrg06tp8Qoyk71MzP19MDK4Gx1wWsy8oAWkYtari9+oZJs7cOoO3Mhm9thJtuQeZWZTQq4k8LjWA/dVQEUuhP/E0XJOIZH9d0eDlqm52UkoXlkkhxexemtW6pbWqN+UNpALR7aZGs91oD1OgeTmJFXO+knxbvKZFWgOnbrYzlqOPtk2kFjXFPN2bSiBfj+0ZECA4EI93tTaAMj8Ng3CqKrUFg0hb6eCr8aKxa3OhhYlH4XFeO/2KM0aICZpOLmrZWE8JCEXNWmnPDLOJu7sUSOYhkV+7jEIzwBLFbx73EVrQvr6qgN4zR6FxEamoM8+2ujUPoCZ33bScRIIdRKNQ/uVOrAR72kFLwlJ7eGpbTksKcLGiWGklk/epqGPyeISx5q51PRRJ1hwxAaJ/zdRQ1JDXdd6lsakNNp5Swd0xzBR+svNky9OUgcLLPtAQUMM4aTQCHhQNR9xbiarxmOnms+zsbBYT+RLmJGU2YNuhzXrKWsvJMPE86gTUrkhAH1cu2+5rUck7pm2plgtYURQUKqYA8V4dWZEELFD8ezDygvwKM5qKzjUv61j3VtD0XQnwCCdW17Ctql5gQ4p7Kvv4UhVDy9gx2TP0qJUa1kh5L3H/KfWdmhw75OmyyVMlFzgXoo/unhSuxC9jT+nPadhez6mIPDqAtBb2AzbR0JnmYM6P3rcljuyBZOadwqkMPTG2UIf5CD/hiywNJFeeUmvv3hgamJlfZ4+0pqcwxkrIBkWir+PxVZX+2HmloYZCiqeN96ln18Nr6T7YbwZnZjpHu3lZMgFg3AKuMJ5x45B2AhAIpyh5/aTljX4rEWBGdMSZjY9AnlOD5/uGWVPR/vKdcfkqIu4R8UCULEcP1qQCXpt54ustwKczDqXVc/wjNAi+btnTXbFvWqlLBuoxaIgMDc7YZJulGS6tSImy0u0tpVXttvurgs9ZNCm2rNj5i2n9nWTSeOI/1DgqwIBsLUoNj0NlmRycQkxlL0bSnq2lpyY0fS2T1WAoC8eMuxk8+MrFYJAmVlri8ht2EI2ynHwiN/1n/TuKDMpp4b4zh4zj77brOm9TQalabIEgBPbEuqu/xkmriZ7gZEHoKaBFZLTQgpdIkt0Sg6aPHG/quhrMpA/pNCxFwgGwrvdWUauU5gVsVG5SNKn+i4iSdwCtobKQNjrdmvl8uD6jwpOUffZBphsqxCc+q7qeCNdALHKemKGfuL4Fd0HxVQ+TTSxrwP7o1enE+xL75uLfeAQPkXCMlZ+CzzczfD0i/FAo56ghabHxKdsuU8wMBV2h/rHWVgsbw2E+wjwDjw1AAUXqaAQ4sor/2fnV9ouVXDcfaVk33hGI9fTbVu2JQSDca9DWkuUMLbbkj8c8PNVXSgHD4adAjNVXGe926SovuJ2xaeeyGkNy+mSTDFzeEzWCCrWOlIDzjWCJAh183eAWcJ+VgmtFJxa2WI2MvdpVUtIGI0QN/tZCeBJwJmQ0K8bwQSA/vY9qYHvbgURyIfRaKxGcU6eYhj7+tuh+ZcuguntohiP+2DFojxu3zR+ZeN7Im74sk0MUsV588p4om4P2et15EJcMZwalTpQ897993DVgU2Q8DChyHBKvLKeGb77tN51GJWlNZ6ugEmSqf3erqw8iNDTSM04/By+cjbegOId0CDBcmdLR8amzVA+eNu2wieg6Bo0ph0YixR2WLmvMCCT5V5Lg1shZ/YARiqrkFSOUxIyMM6Q7f1YV5rmQ7E4VxrgKaKEvJ5z/T8JdtL7GknpHh9IbIDJm7rj3hUjxSfFZUelJuN24neQwIEyAA/up2G8lTKPI+GBDArJ+PrdFjRJQIXts1bD+GR8vN4eHeTbbT/1/XD64U/StmuP/Q0yLwJPqdHjQrZxFzsRYSS+34PnRVg+7JAi/9bKMGPvMNZMVYTlKo/Gl67qQAFFphYpI2t/BKgU17AEO8uvrdWwa7FzbvZMFAoaHczLheKZJpelMqCe17mYBBqct+By128GgL0LWSsTMC1tHbmUDcadt+PQ3jkHJuq7+AzEvP0JG4EHlQw+JEWR3qvTBik27SIdlcT27isz6q93B9mDeb++YJpOVAgx90y0Zlt+EJhNvlqzew0MLE5ACZbL4oo+IhAS8+UzBC61tTcRLG4L0bRxotC9XU+zkShZJD5cPPYh9iwMCkh8Fn3s/yPXaw6NxfVtWKCXA6nfxRvKNZEuP3dkVEMTsTLKQeCtBcYV/s4EVW21qnXLs4BLzzAA62aGl102p7cK4GeifTB9bgjsa89Bv6ppWWLZciBKuerMELw6Um2jQ1FKtqNAuLdzAeWlQRbCZSthJHieGmB86dJfX5uokt6pMuSUjw4YA4qwKSDKHHrNRB6RSWe40frsoCJk+Pig3FXrSOojqRxYPEDEKJYEx0SmS2j2nARSF2MWZDFdOV5rD9I57JPChwtmYVze3FG/Lss2Znyorf3BndB7mhgZWNj+pJudLBPg/hWovtadteJq/M6SzyhotslBSyZwurTVhFv6Zsgy7j+HWng1f8vr44USMO8QlaN3Dz4U/ea5gbFUNw+s1MHgWcaNX2wu/7f33DRInP0ttdQFHywrzma6gQUIVrYnlG3cIQZwsaX8XLRmnwiI7IG1+AkF2ICHkR6hSWG3FFgmeYdwLPXaL2ooWVgfEc45MPy6YRmpAGFFft8yIEuL8+N+u54x7Rr+Jc3pyZKvNCw6wokEv9xVHPypL0e3lXM4tQMontTn/djD4ZuSpPP6avGhgQzwARxbuVpAyaxFeRvW5B5TZI58RiJc8gcv1g2U1DMBEO2YU/Pvn0qnh6w0NY0DGukOaTnYFT9+2STVZxD7rPihvXtHbWaLMIVoE2v/2WA5gUmOPIIHCkc8yHNV7CUePU1YuLTv+Dp/LqsZ3nAY8Hb1MQARhiUGXvcjWuQif3UvBCIMkc8+o9OaTU3A7iqp2/Lx0Y0ySncKC67fMInkiC6G4k7FLtxVBmwcaFdfWRTKUGe9ZXkPxMteW6bWykdoLY7tkoFYaC2NRvIUc4rZEaqC268m4k1BI1NhZ0o/OsmUqCgPVj1GWx+hyIk/bMmr85whTqCI3bvascT3jQXSe3KSQdB2psKIW5eAYc16Rw40cWYoykGDsCMTKMhHy6PN5jfm0rCHz/Xv8QWm6nzvAMWpv4qqGWHQzVzB5eYBVkxitEtKQVQVuGOwSDDtoqZYQqp+BYIm1i0vHRiWuKKSmud5uIed07jkZKclw/5z3z4M7ewsz7xiOqJ1WAxEqa4p7txqtiazU5kGpqgtizzxU3T+pmbLo5Zg6lyLLG60Jr8yVfheRGd+4c6HOnrbh2eL/oW63OKhUkd2TKurd3ocb8gCwZUONphjdrsI7xEkJgdMv9xfglmeBC8aouh/KwkE9da/zQyQGd76XtE5lnzrYSYEH/oiX4d0BUiV/HHzwP1xOKz/oKlMt4dTA/kNHgUggCYGSvGJQljQbJT6GobjC+Xij1cwZ+wfy8Q49ORSS9srWQVltVQhRX3H9wvALAopxwp/qSiJp9tneNJX4k/n5WDkJ/ZFivG6gqAYrQVer/Nl8UxLifZNG91SNmCE4nImT8FEJBVqrTqdURmrKAyDXSBdZqJowy8uN+59JLxysS+dsSiDBlBvSsMgTxTIhEVmD81ziR5qeJsrJxNNmK7B6KhL8xlaRiUaSeBksrMEFKbNMjYG/GiP1kupqVBKPE3v0T3gBA6KbdTiA+Ua8qTjP0Y17thkwOT+OEbUHP94bIeI8OZawu7Y0SFbfXYSDck1boNOOpE3oVkr6e4+ejMQM67xuuqm6kRXN+y1zyW0XIaslADC1EKtt7cYUaz5GSEAhXTQdQ75hwpMszgBKLrd+RfSVIILqOMQG2AC9hz7X+1sRdr/RHAr+lciha0NuN9OHSyEA3hV97bEY6DFBtk1+vZdTGppgEMxsDTr3GtxXhWcVXgqKM/DubWknBacgxr3QwqhYnyVneZEE1WV4AD7Uwwc6cpXLYkRcIQdPZIW6V3/YcXAaeGI1Y27B8LhavO59CuFemr/TVtKmAdKk/sf2Y73swnmlMvyFGr3eWyc6Z3u0HPRNENJn78nauWWW1HDifcNwF1eHg91Vg/VH+aGxmscvHDYc3lHu0QZsIknZ9yff2c6H7IfAjFlQh0y/KO4ZQ3KfbzcsQUs1fckMlHAAGDVbEY3H/FIliMhwb+sKpfIInN+divjrrRaV2SxqeKGRe95GcEGoEbzJeWtIN4trUrfgQ76GRTLnsNKP3jFx1E1Nt4Ms+F2CntrFYyehPusqMEKL9OXlxuktU9iYzrTJEwFboWYkfLK1CARuBpexvYNLH0R4TNllC1DdgV/cg/xzbK/8jGFs0ccKu2hLt6DQaxueVJjo9qOd9taUfsKqu9R4S+SW2DaPoI9WN5pVoSpmvVjGzsoAzOEvKYm0VzZ263xHo9AgquYzluJH7Ml3A39xUbrtKDG7ZkRvzGePZYd8Su3symLbpHtRc5jqyvaaVIPn+3jBBmRaXCMoS/57S3s4ZMt4rjp5BPY9fmXnGCNYEyN24SqIIO+mmyYrUYO+jJOshBY4X0/uXq56lqTJgC50Qhlu83AiYxDKP+7TzO7lb85myEPBNjP2MTP30iA9VYfZ0G7XpChHxyKbQndwcSgDG7E2+2onVoXoihYl/BFqjR5n0qkjpvOl0WOyvHscUPSBF3fDHQe1/P+ZnULHcmQj9T7mjyMIvUsEyoDogD6ppEVRQXprIssGlE2Op/EXwXV63pqrsLV31JEItdXjk6ptLO/obDX79/vS7Z1nYwtmTQVFei2OrwNgWWmvKo5EdzNGH56io5bgXNhU4hN689FtD3lx2QQwLTqTMfYnhRds3SAnzgLRUsN1uk1Xg5uYszZrr760xEtit3Lnls92I8cwm5KBpsSgo9dU3YNURnpOP7+y7aVtEHI/t3mk7HGAhVArSHzQcqFXJDdKpEf4MhbAnADEivK4cClfKWW2YmsfuUQ+FBBImSqh/r0Mu9HbsV0Mujc9x7WQcYBbjSVbnwQZkaJJjp5gT9srk0j3fmL7hRMg9tOTdJKAel1N2WOD+yr7nDGHs6hdBKqlliMO9cnFS49WxjoyGtc1eaWGR5WveiE+h84KJSPm9MYpTI4p1csFifp4fEWeVBnhlntPO24KD71vazRDJ5K4YJyNgiG27WMUWdIMqnQONsqhFgOiZzZp0dwlRphIjn9YPdzcegIoqPZEoEGAQr+LIhm8MtOa2mSJ+sNR0XOJBxOPuvpfQCka4rNIMg0UNxi5aVIUHoUwuGYOTYT2oQgrufAxdQa5CmGO3CJ8u44RWAEdvE4/dAu7CWCCYVqfWkpviHBqdh0s0/NBwmw225Tpiop7Ppf8x2X/oi1nQHjGTarGDW8yEd7GU5yGXt0z+kdwLvUYRBFn7XYF12wmBLmNNsMDkH2xTFlkGq/pcNOlnjR8Hm1isyTuXCh9NYyn5Q8W0Kd7dLXqbdvkI0P8dJcFsAFfaxQ6BRqb4kDgODu0IlzzdE0J5zTsiDyxgupPYakTobFIT88rZFS6kfBNv+yUJeWo4fTjtNRv6DAlGCSuSUEV9XUm1hChZolheu2D2k/BklyhHAnQJQgR8wZrw6DCoRO79kyuiH1liQnkJ8vHg4xvhFMmeFHZp1Ai4HVmF2Rur4s5xy8l0s4NR/FE1Zss+5iPQQmv+jpd39Q70UicEHCe/1RG7qGMvOA5qrzbSf3Mud3zx1Edpvt+8qusSHJfo9w9K2dG4P7+Li+rLCn8Y4Md+y3p9ETdxdoACaOzzjiLL4CFg6SDRONjCVZfLPmMI1yTY0sKpfLC+EakABUeYtGGA7TSokylFzN4RqTZ+WL/z17aPmgw9epjSPAnuf6rpQhtjLiI8SKhWK9Axlyg4FaY0Dn30NbEIoDdANCCGuDAQ4rwavNLGTdDpct/SQZjX475FaP5UsKG2/fufpuOKQZL80uzph2TeMwnyVzV0oGHLE515SkWBcVP4LtznitdR31JVhskIHUoYqoh1SKgbznbfknZ7KfQOGzNaS2pEmgK1UDJwOG63UeDuAy2yFxEM8eYulMsEXBlbyI74QH34dOstIwHRPeeOKv5cUZb6ibLA4ja1aYROHhLgob6Y4X1ciNCK+B2vu0NzNf9pzdl968IyoderzU2VFhEWnZMb+61TDLRDxXxp9O9W0TkKtT7TBWMKKcPW0qlZpXYaTzwXklwxfVo2ZEHxi9xQF9M2Cq4Z5TBTV6RHgOQe4aAah9//MUiSxA1r+t03vp5IfBuZoYZuiKsN6qA++eo+Xe1YFGsjffhw/Dry51wzqk+qjyT6SonLvz4JkTv9ppe0AWcJelnlpnlFjq3ejjhLWTfZpCvPTHHpY5YHUI60eWLnnKNAzDz/oC+cAhlxQlDw+uDkxffpLz1MYcfn2IEfhdx2ssypBBAAwgrttZ0nWZFqGkFEtra7CEK7GBmWW2d0lzzqjNy41tGwXyFtKJ7ukSQZDnszb5lDr+rZNN3NoPL1n4XQKfBB0+IZJKbcTYcO9jWVa9ItRRfppnjzP8sqVl//G2UBZh/s3qnz2KBU4Z1IzpuusJ+jIilx7b1BAjx7bXcZ+bJRquEdqdYlwNh3bnaJRTQBHJYOoDKOWu6RWH9fSjJpSI7cFonWKoGdKOCtwShdzSi8XfmNf6gKzld0onYEahQWDcswh8iQJuZ1Vfcma/sTuJfEKGZMx7mXy+d7WM/H0Ag5SaVTAlobjkMkSLfNnFlWcTOrOHNBnTUhvFHr+RYr6VacAjZ3FKJiD9R1XqrrkIaiIGI1bQW1JYeMga0dZTpLxIFxZSH+Ivb/zK/IpNYP8Zfi6ukietAcyCI6ktn9JjC8pKDdhV6yysyYLdt2VmfJ1jk4Mjjzj+jdJ5gbBQPM11hff1AcQJs3KyMKJGe/zUqjwEHy3e5+XlTSFXPKbB+ieP3v+7beqVk3NLVQLQJ1n24HllHFp1poYaF+V043M9/LtagAFK2zbA7GTf7zWGoQfOonibCCA3nSAVmn02eBJVCSevExig1D23oCllKkoGWIv2UAohQDxWfh3Bs3hB7Al4M7/VQOX2NiPK32/l5RIYced2aoxVjNjqCWt+MNH2iRe/0wHQ7s4QUME/SFJtUiqpYtXrD2OwG2HaH3bYXnDG74Q9zBeiiIWHjN+BqT/wIuTkOBK3ZItkgDafe5EUqYFu2K684mUcqb/3+2NjnSBcTJK63o6mBUPNL+uJx5jVTRTDl/grLnMDLV1vN0d0mTC6t+tu6/zkiBAho6aIRLIgbLdbDCCJ2pDBqkO/MneeRNI9avBkANZNAErLyFWCKojSV4N82fj5AWhBBsGMZBHVZBnUHTcwxwBPn/Q/jHRW0vZVzxIJZwGpUI8hH9mRixVKcmj0R7eI9XCpkz4FwqNVziNYGvauIzE4eQhnSkgQB8dtBqbOHzTdVhygBMBvofnLP7r6d28uy702rtz7aH4prBjUdmXf7pCGrfb+2a/6I9de3sIaBXo0sxr7GDzMsd864z+Y1z0rFztKDbMc9M7xr0RtwOe8xf9U28P5USjtYDy+y3nER0jNy+L2xdfoagB9FwWUByA45fYoCwkmadZwY2ZpVav+eqDihA3JMB2x49Gjbee1oTc3deRkVSmIf5zEE3JrUazUxEg/yylF4LWAklu0tHAH8RR1wIGZxj82lD4OnZPEAOjYSEvNQ5yJisWWIcg1UmILzlfLZx1wyBAmQk1GA63KTDVaXYm7kTO+GSFy7N1WObI02YH/JLNbauXSTgSx2LBs0a8vqn2TpkrzSPg7IH6YSPvf9DrleZ8YevuedNP4JLtWcrdoKbk5r5CmBjrfGuQe54m8affOA5n8GigO18L1ipFeISOUvDS93hUpHzAXbRlJ9xeAl9sf4AoL9UEy+td6XSsZr+loRvx1oyZt/4qcrTmeXGudKmRHrVPQ+lXvxKEUEDkiePVl/3pV/ueBSAADa6iZJdfe+BKRH6TeiBs7DTbHmvuEhMQ1jDpCb3aWRyS4jlV7N2cHv4oEcwx8px1Gx+N77Gd40/7J5GiCfUqzE97p1gMVUe8eLDymCcEg2vybwz17EpKZB13CQsBDtixwixU22D/Ke5dn9IqjCHaU4CJoafIS8YAXJjam2LZkgs3wjBFOS3cUx14UKkgNjKzQOtsEXagpvPTZiHdYNQ7S6guj0Y9qVC8hlAXr8ryOsMztcKGssNv9D24xhG70A98CtbeT7PYUHi01dLw5Cb3C7iPteXgS8ahY2ecZADmUFLuey62EGJ2USzP+I7T85U9u0HJ9AvKqpLrmHABtqmhJmF7HCzGK7omCBCO2a/nWXd2fMm6vik/G1YinRZhjpkZFXPIEIl0oCgcsFxvJKkjulR4E15bOS0vXgzcvNpK1rfJct8l9jBHk0Mo/7OyNIWJSr+H/jRWaC6TpLza/BHiKuwhy10A3qRKlqbMduZkuGIcpHM57a+Bzl4WPRjlgjC2XWGh3cDNhD5PZy4AegrPfoEVUuX87AZdZp7/EePgMhUS0kbB6c/Wz3NJHRWheV4RHYulQhp4xoURiK8zKtmzieB7iI+h90KlTpTivBMTwv5vR1+aaNCizgoKXnZSsY7t6Bhbuwu7mZbSJ2kuYfB6AuN0xWvs0a0YEVStJWNEdPO2TJCJ+ALpXI/NYAOpZy/x3W9HaIUMfXGwZkgS2voQlNieyLdAjQUHpGt18DTcUXnq/Y7u9QNixPqIQA0WUhOkNWgGqKoJsjcUcZr1TzXfz1TNcmbAAHIsZc9+REAO74TMs1V5yT8wXeW6qmWbZGYvnjHEVY5qQ6H1ZFwKoA643z5T/gcF9F4Ypm13gzLxrS/VevzvCeem0PPW5d47JNwwC0mB2/huF6Zns5jVVBhpCgn6W/1vMw9l9mKnIMqt+IgoT07wzu6/5FiVTZy10iqKmrzcyZ8oKIDiALNIt9q2DpQv+PrX5xFa+VLXyZN5vDgoXYBDR6tWnPs/W5414V1Oti1e2z5iYkFYa5uZBTg3AOSiC+T9Yl5BLq3mxSmKgYyNSe+ikB4SnOmsgOg5HL/5w7Qu4J0UgGymj9pzZ6KaIHk3RC9kqAZGL1a1y6i16ckg8ZA4EvInqAykOaJST4VYA0RTXoRLfoevBmKft2rgp7fC5HSyphwKBgZp7xzSyneeG4Yi4Xw32Ab/z/caF8Ghw1atdSzshDGeTR20J8CNFerMgjddk6g/eHs67tYSE34aliS+Kan19se1zQ3ENBP1zqwnv8F8prPg28qZrRmfC/pERq8T8/Tk2+uwxWfRSDoE91IrkICEGmdz7O9KCixlk7eR9nhhRt85TMnGOJyeeMwYeAdvPQKVfa/0f73M0VdqRHGQPOCnmXgV1t398br4aJ2laiwQxcQhv/ZBxkjDUxd9k+F2gWqmlyPV2UTP+XRxt7wrMvVyvLcOHlbNeABO4XBrpNq3YM/Bsu2386Etk1W2TG+yh2C9xh1p34w6IEgzkQyvyBth5Jx8G3SPQQqonMTlJO09j4g1q0WV0ZYuHLije2sfaQFkvpWuZiGlXcJbAY4lmKQB5OSHJM2f78qoGBhOvXArtjlZebnJ2zcHSGv7SWKjZ5h06IwS1GeBqSWnd8RE9h/VENx9+BNX/0m5ugeq4uzSmiplry7Pfyrltcz8VXBgp2UbtoMzOLQX26Ob1ys1Y9dQcFZf/fKkdAKawDY4CSrMK2xWiB4k3bWwm4oQeJdprqevg60h7Dd7d50/QMJaLO+4pb33t6LwEJhQHyfDuBeBKdzaSirJaVlJOBOkrh7Lmv2ZZ4eySJuXe2AiBdcie0PTod0I9X2g1x0cQXxXv9GthnCtH4wYdtSKOtSgO7+EGdTz+GqvyRUyN02djAe5kpyJTE5WeKzzBCSXpj6zv/rquz1wxyUD5WdboE0/GgzP5ldpkssClRkYE+meXxnM60sCzbiNug7Y54MoJUM0RfRaLos4bLVoi/fF6FzSsP3UeaMOQa2qriRnoJHQu2HnjlXOWOjwZlx6JwQfKeBZMncI2yHNzqdUO/a+xE6dzacPq38Hf9ENPePmNTW3I/c6SjhBC4S2EJ+MXA6/fyDGxLtL6HE+hA/BJmxHQTfGqbO9qY6mYBnJomhRvBJlx0ts7x4XbnUtEQ0MTtCRVeDuYLIubwX9uVBSL0vPby70dTv8XqGHdaQYWUJnJcKZYOcXFGO3wS1UQK9a+EefgvBSpx4Ta3L1VpuM/JmRNyZJ2qPdNS+Mj0RKDqap2QMVx95DkrAsMCTZT65M5y6zcZDAT3y9xy4gzR0S8opNyudewBQZRYJvW3lxC9ALIjpLLIiZ2OY/HdvzNpF7MM+dCt6XsX6MT3ZQiZXWUlWMeBcIO2+ner+xMypql9t8o8LOdJyhsqEMUu0xx5UBJN0Vf1hVru2XbEQGvLgDzJ2ZNpaYcsBZOEZtkt2bpcjMr7YW81Hz74rcNi6EAUce80O3iIhBhM+yqaIkYRHxhLjcsffO4OegrQYg0mq/2UIbEQ74wN1FpftZQ+x3TnV2C5AyJevGiESyxVhP8TRAeQDfNa8IWe2zBZEIStabhD7uFINQ2R5fwXKSlQ2CLQFtnTzDsoVzU72dNCZCzmTE2AqVHlNkCixVWlopP1oHi0lcK2S3pWDUIDsmtBsVS9A9aW4R6eif2m/5nKgTGwPi3QgQYtUxunLlE9Yro8g32SHXePKWP3xJmHw0W8yRNeaBMbu78AsId481tthHv+Wqhufo6TKIkrjLLpdG27GJtgoEDCqVrRbu5prB+ilX69oeC59AbTrDM/jXkmBW+wKOwp5F9u//iIwOpl1TfEx1u7qPYAmLXR61kNLf7f+2SXCh5LJMEdudPeR169a4Zrknxg/uSV5nEqkUfy2kA9ZddHvcs6a+DqEV//l/DuVxtretv2KojMdV8R/uHEj5mGarlYiptFeEWuSaguHlX/oExRtcyIT9NffWDumW1P2cZ/cWmjJewI8DJ1lBuavxo15jUliaP+mPLklRLOdFJw1Xedk7AkUo9pIqbWnXZLQTBTn9CjUP/H8FHCAPc8bgOnC/7ZdjRDP2WBkXxCI9T3dCAv1yamZJ0fPHBbjdPI317iRecck1xThMII77AATU+oTt5M+l4r3mEEsyEgWqx7sv0jwKjYR6NkR0NVy9Kju0Qc5yhrzhchB/5f16DH6sWT4RXFMOC48FDh/RcZxwPY/X+neEcLZAuVXPTnc6B7Cfj05OQz2lNfJr05Ifw5KCJKvhSf0FFc1NXVesJz5zQbuzW7gyy2P4ipddDQC+cLhFasZ9FoUUooyaESpN4MliLcD1WLqND94rJgg7K52+Txbatq3ZuRuxgrgn3nGXl46ecj8Y4ZmkkYcn8g9zoHana+DstbKcL34ZEhWlLpKv2twWqcaesTJt/QWIOJ2y9Ul6CUxcvLlp1wyXbO45oSSXIFrh5kiDu2dU0yyfRNqtyifxkJatElLhoSyBv4aKRP+PwJ1qB1mGZbF0sfqFwDhY5VbSObMfPLEdysXKSs8xWk5WowvXDlINsV6944+R/BLNnqj9D2/bt04B9trVKvsVyf+hxwiPzb5gaXF3fcJ+kcuFE4kNSMu3Zh7de8IXTIQQyGgN/h6N5jEBSjYIjHEAs2Ps+0mYB+8BhUPgfteszhBQ//It0NEuQ7zu5I8WWHrrGgNfrN8dQsGwcDR9QZ2wjam3gKDh03SnAHkOrtaGTBDe8ptDri+N2JeBibT8MMq7UDlt/no1TEpJDQvBDKHVNRc8nEg1mY1pww9UEDbV7AVEtakT+vdhDn60bcALjuPlWveevTiRd6p3raSzAoUGUhE1nItwwQxKEjCXrA4KUbQZtMiUY0SRa/Ju+YAS5WR97NNupEr5N61klSE5RbZxkz27/GkLNsq6gLtKM4cS2kwP4uhMMs5gGSR7OdPA396CaUwQHWqgXbAkUGkU9NP18sR2fcu02j0+85RVjUtFxcwtndXKn9QExGGw5Lm4qVG6VHV/nxC2Gha1eNFaPBnPH809F+TuK6Ap4ae9t7PLuCFLx2W6g0xd4gg4tzchdfznWa4OloBOQKvRJya78GFBB+gCGL0+4Ho+d7KS9gKJmX1mankmJIsFNhuyx9SJBvJUvEam95NCR0BDvyURtXGMKTYRJf+/czdIRY7BisNZ2hfgmSSXa1w7cZUBMQRHiodbdYFuWBQIRHKHuoyuFOMAb72KruWuLl6IL/o/QkE54gC2qwqwNX3BrO4Vq9NHd7pdca9HexS5VP0+W8D6oC8m0qkScmpA5+7KyM3oMLuVx3JaM99eWZsBXFd6+H8/ReRH1i1Ne6icMXwFYwsk7KaepFxxgt0wr4LZCaop76uGxIUey1M7VOiVEJt2gloFZrkw2CCKaRtAi3EkezMWwdSLTTS3NSeqkeJYjon4U+trjVHwl97+wr34faK5+behi3GuwixyXCoO868Nu/73iI78J5lh7QGYXTQ9hkOcVFPwGy+9heZPhfY+U9bIfsLZSMpPfLrhwf92oCVYZSTu+JX8dzdFoyiWxPanVmY2I1dpG2x4MDuRdZbYLlpNeHgXg+Wa/lxc8IYOHRSts/bC6caUudf0LxsNjkTbvtslMHpSZ45/ySXAsY9E2NKT1MRx86ZN8SpmuP2lsCA82f8mK5slKfSwByL5+46VQBxRulJEk7KuzXLtOn7Un4IuOwL0W8hdxqz/NCXFULyVPLOCXkmnx6ERfC+Bv6o6pvpA0Ajl0FI62S0/PCBUJvfSpLmRG8AyEC4b0xjNYyRlxJWQfXBucm5cHco+z/QQ7MhuNAmDZ+5giTPaa7b0xD/IGpoUcm4G+YgU5U8ONpV0jdkcGiOYwHa3B3Zz0KxMZpH1b/mExgSiImAg18wCnRI6Rkn0TaCchZjZ9lNCiqQTLSsa3IUPIpWA7tAPgl0ieS3KrvDrtKqRfTUlSEY4IqeAR6pEiAuoiZQljXXuBLI8GgOdPs+RgrR2CKR1CxIhhO6ZH0J7ShovXf7sdKnawQHth60BVzVx0GyD7PkNNal5ps5jL1zwnsZ4ZOpBa8yeS/aEfeD61axhS/DBSWCu957RObCZOkGk4f60V9/p+eiipog2tAbTf98bf+oMToY0j1sRpsOGVAaSSf8blP+psblfjdI/ePJQ76bo1U4laUtlXO16XnEN7/P4nM4dE44xlEyeGafoJqBmya+iPqKI0JEZXKy/Xbo6WF+z6YtfOo4TBLIM82M1ehVX02Nrj6GV/RJlRNeGs+PA8in35oYXmolkoVajaKLvFD4EfzeF533ZLiY7Z2/FB2mDeZ3X7C87LUfWXzoGUoVhgt4dEhiNLjn3OvYzLMwg9pUz1YJE2wsBvc5l5HjfSQ06nV+zXkPYNPEsB+qIJd/tdnpw60Dvp4MAzjAQ+nnt3LNoDjRME3b9rtC1uug/IX1goT0Za07QVxjGbRc8doD+WLeX+5hZKqmfI/GJiYlanNmfOxCot9nrRdpE6oIZfS/wNdGAUor7q4oo1biScGq6u/vPTqVsHSZdDilw2Fl/UFCbO3wwLhbmri23cU0psX4gPd3xL91ungdKGG+fsITdzW3a1b47UdtO9bjulpwD6zbqyAtIpzomnPpGv8p8BKbTzydwdJ0BOVx26gI5KQVOTrCrkedUI3es4m5qZB9p/Qf1JW3/Ev1ao2H+0j46cVHQjixIS3v7BD8r4DiJb2cmrPBgXZpK1GSLzzf64FsvZvsUsKKliTg7qAmVn8KU5+gRmzFw4j6XDI77B2MH4mUOOOoL5clQtbxP4IMzFfHAw9dY4sEZ2suN/W0PL4/TD3Ikhc+/Jd/1EQVndWwLRgGaYqOweZvSovXal58HANVAe80/B/4nBIAkRY8iJ91s1C6AoFmJYOSqFCUaEi5MEdEoD3y0shvUrf6QE1Q2OyLLel//onlMNIG1/drp1ExcC8ixuOegaD+Myc6rzrLKlPKRM48zVaregX5E95F/CGmTzt4qcELhIcIOietparpLH1To09U+9zPrS4/zAADJIGZghDZELfGVwKSnQpz5mEpxODmDORhXKg78kkKts+cPBgJajmfWPeplBO5GVWLki3XHBmZjftAmXLZOVfw7hbf8hUjguokgvILIlT+vlQjU9IXVPxZoapOcM61WulATSZ+iDmIKypMKuUp2hlFkiB4P54P1qIeDVV9q2UtGcD7ZSlMinI9mhcHRuEnhaQ5DRMT0s4tL7pzudBDa9l5JycbNwOW2CASQefYgfQXFUHhOppalOO8N0+tDtfDt/Cc+kLmc/vZ65pDrszvth0ALCM8J/vgSN39f2OwghNjsPguTu80ETgIbRMSElBktsguoty6p2FDWdVcq+xKnlWYtEEmgvBTeTjWJhKjhiEwfse79/vunOHtt6Q0Y3iS+c5nt8D6sAupuVV1B4taA6/20EvUhDFCkBZwXhObhPWIevptZwz++4EewZpuafD/U0cp6eTsiSMHT71Sei25c1I4S492qJiWQRdsi49okGbbDyhTDPfcdQfA3ZNMUQt/GYPakjn9WvGIurEDzXQ0JLvm98le3ikBBFE9RnJbpmEXJY9whv4FwpiwGyViOSbzIWNZnD9ppQMI8Cl73hCqioSuM6Di6gg/mkphIo2/8uMJTU3TH9FevkxxaNdXhsO2qX4ThkZw6gE+obnWbRei86QmlQApUpgGIvhpPVDYJ3ZHMku0CcQ3iuHpA1tFM5JjNuipmGrY/o6aqBLWjLL5SlkZLiRZhRY2KKRtZAK8EHjngz75kzR3EOTVI1bNxP2eYfIC9Hk3k/yllFmN82IsQ/3zpJ7ErnHw1tw80hHVtEjvDNTCa2oy3mNt1wIYYsYhlWl5A1bG/9vkuhirv35AmyOOmyOav2HYRSFpew/IrdTpCnTcWDhIbeITSr9C+bBsEIbzgntKQTJ9KHNXQDeTZiwJV0idqo6s2sAbvXFvXz1Mqze3pw/e/cMAKm7Rk64tC2Inhk8lwxi9N8FW+BGNKKte5IOEDHvxA7xQ8w7rrnUbvMRvTgTIjLdHmfAdeG7ubp4BtXFeZs985sXtihlesQQJl7KaunMdbVQoWXhcdSWTpk3b6VKaGp/Ul/X8pKcEEvkgPPdAwzS9ukA6gplW9GUtBVCAr59MobywKDy13Cl0uQOpDFjaQQ/QjLI44WLAUVAupGOV3heKPxbkVapZkaNEnHXjiRkafai6kgD6ksiaFWsKMYvzW8og+wkSrEv2512TmXq40ej7ZUL8DzHSbyI7bNhR1SX4NLbWu7DJFUGZZHMQcX5MluPcX1788tdwRR7n0gDT3HjtQhT7X1tW+z3EG5IstX5X9egMyFEsIVM0P+tLPK3l9TY0ztA+Osdk3XVSNWrJdSx00l9rvZxvNTkSkJiuIcE05fZfGBcgSWAJ8RDBhcbGg1qqXcieLaVx15ty5cbdu3dxx8TMMwesHlNCE+qlbEvjTxpiS+PdCnAKSP38g60HPPms9FSWg8CZByv/YNAEkOjwfQJozqB80dx2IsMMAaHUlwnvjFzvGE1ZM2yuU3n5OygjvO4QWphOqiJDu6Pq3Q5qVn869g0RXyK/9Xp+FDfDob/kePy9j2dpKdHdT4ImTEdP7dUDHfCvRDFqNdMaHAYLhdc4JkdlVxKSRuZkN+7rPZxZ3u4OlTFaGbzNqkASwtvJMNCMvDyZHl4V4mQL4JaGpyCmXR7nGLS62JfaZBpft5mlhNrlidhCv4HXRAO+9CdVIQ7pxCakiXcTfCiKH0AeB494VPZmZhLLuv+H8zxkGAKxVAHh9wIQ2WDYV+z7n19Tzw11PaimmD4V/4vfYmTWzeXOv1Y+oatAbGbShiazd7Vqa9ntdnKpqZG3C5dF/zKyBG7NhV360XSY2hJ+oIZ+DsDjoCS1tGggejlSSg/bc0aV2B91E5kdigqtorqMrhKbTltGmqg1AnIXSBinTMc8eMLItWAd4RTiKz4udnC1U25FczU2xztS4ddmMSjGwmwQXxfvymMPFTZ9/CYWZBQwX/dC/GqNfWzb2KrdfEVx3jQ0qsQ60dt3stNaYFUMw4BOJ6nOJOl1qt7md3HhvIcvM5UVti+xEU4rpkqtUPMpTWFX2MxxbB88Y4+UCVQLWtSNLocZjTtWPBU561C2YVmwowse5v5UezZK5ruJXMXmDInhJIx6l2dt2WO8bOmaCTFCI7PWIhV0CRUxIaDiYE0MHTNLShqgnycyJA9lYlRgDfAk3DHjZDcuy7+oGugVyCsTbZYsyxVLBRy0JwKDTMauirO3G3vqCU6LAOnSKLvd7onJyaRpxKBdfq7ChLMRZ2/150MTkOndkzvjMSoV+Ch5NlmO5/dr+z5yvU+nWbwpSHHMTw5f3BptZBLO6Db0Tv24hl+2NXLNuQyNCUHfx1NHgq6rzCEviA4X8FGHUmalPx+/h4Nxii4ZYARht2T68TqDK+89ZogDrhSX2ZFmF7BZa2aE3QTOeQ6g+R5bJ9afCuKGw0JZFnLM09mJqc4yWR12coaUinKhLd5TZLo9HLMjcOZYw+ej3vAE4wqsl34eUGX87voD+49MkZ/uKoxa/x+Lprirv8sDfXuatDogWgZcXWEGPuZjYzrhskhpQk7zhYheUKCnsN4v7ocesb+v7Ite84da5NjGkxsyRK15kdbEyivYnuoBRfjTZLJChf1Z9lYAqExLXNBFt+WRs1xfzjWfEjnH+5Wtfgm35x+6JFgjZx47vj2YS6nhiqwCjaKK0aNPE3gpP59W/NexsDe9eNpN9RV0OKszd/50jgwRQOKHoJD7yJRAPPhzay4quvIBDx300AYP2vHQNKRn8sd/FqHPVkByWWEJWvx5Zgsp5Tlc5yYlyVfMbO5fyaWMMz84BT5R8DlsyEvQATARl2E0ajDbmHM2oEClgejFMNDu+JzsbCQGfYJ9UyaygU+5r8oM8BO7tkg2tWQHHev7IWpmDG4C46zfrx+9v27DfuZUgGRbd3sc2EKiVJGilKwln9zBNb/CtqxUdnBsvK14wX2cOHLDbST59jT7A9EMfl/Wgy5BD4SIER+AJdlwN5mFL6EaDAyTN2oLECDxeNg7OX6Cd4nLCqyfkWNJgiqA7ku5TL/qf78Xi2AzCiqJLFAzDRHC0/OTJ2Dafkco/cPcFSHWr/F26v9+9O16ILVeflBe1YSpp0sgbNqbxJCrhifsDbXt5w+myczUe/XZ6EvZN8IAsvYKhmFdq1BJspmZ2tBGQui1t8RXvR1ceVGuvCK8MJQwklmwLh98dwnovYirvCKVPn6FEt54mYsEJnTDQAsbnIWMQc+TQnPRwGQggrWUm+nby+ZyDbGVpxJXbiw53+lJOzLattytF0FD6y6n2ofYeqWkcRazIXBuAglYzgf/jfkVJ+zBxlNgarrM4MuymWFK0f+Q5XOJPyst9zQX7Tt7xtrhJTrEF4729b7vT7ZeKsrU8jClDFMdOTT40jqUdALHiT5c0M31XMMGjE0suLilKypd2eekYT5ob20jsO/THrL4kM1wOvLm9+rbn852muVK22NFfidBJqs/4iKgWmx0gv0riSMedq4O2BjbqU1w8CD/5Xu6nFihdGkuwip1uE5epq3QryREj2Fe/6H/6vwPjvIb3TBSh80iZSA9PlJPgulShShgaB6VujqVnmEWO2+NP7Gafg69KnBoWcBD09IdDRyWeMcCbrrNck0+O4R072cg1r7kHI37QspVRNCwLRj5ubMZAHo/3PajQzBb3PTjaks+CZ4I/ik/5le3/kJFL7MRv/iGis/p0otGtCfRTMrXkliDUD1PWop92laS8c37VZ0Sc8kmaFXMuCkCurrs/LwKzXyXe/cPEWbGTgszYR74SP0AOq0dLUVtBoaiNN/V3k1eWesonWpixxlEZ641nrUS3rpXw69f3SdyrOkinmcvSCH76dKNdSbLfhWTRM5P5EggkB4oDcaDV5wrjHBpG6U3kNDLaI1Ghun7SKCQ2on0QxCQp6tU1TmaI0KIDORPhN//0MaNaX8OE0C+GE4B3acXXfZg4upgEIaf/VAPR9Kc5LShbUlpVUjTRubdeXJFMyiusSxn1HgJyzrEyGVth3f5uakWeWTJWroXSIEgGmWK6qbtZFDLVWWMqB/xMXTh/yClYQuReRAjg6mIWdmv8WEzyjMhloWCrWjvwWqDgHLRtLYU+W3Uv270sac3o7d+Iw4gjYdLLmaeoaFBgkCjto/QAvQlspjDt84IPrh/l/3lgcVchmP0uPPimwnhb3FqIy5JfJudXGP02HM3BF+meBRLLgTo21yGuSsLqmzpr59c2D8x6yehVBIk2Z9uPEQArQFptP2ZC52lL6V6EyWlrDgdIMOWE6T7WME+Llri9XXoKE3IAgRliyzGiWuv54uHXeR7RD61HAg0Z/XZv5X1esiBK7E05FNZS6y6ermwh/64XEdssI2Zf67XGKSJYD3cUxBw2a5e2QbvQqpyOL71UG7NaL8kBHq3zUBaY29mEEOEW4wYvVCJwyeQ0s6uMx8sgii8kzMh6dGH4CHpQzceMdm49OIOuSvmNqUnr1nRoZbGXt349MgZonBeLYRUPUUe395TtFJry1DgXxGgTsfxCXoO9Vi2fUQG4yPVsoPboOoS3+TN+VkrKURtTjlEJKIg9W+9XJcqRG7VoeRenu9gYm5GzGfLtrMYhOKGlDr+m6zqQUth+AgoPaze+AYXoXcS31fokuizfJCEuxt4CEbWOmdTQtOvcnjJAwb4gqT5uTGnmzJ8DKJaycafwVYlNbOkHM/NKkM9OPqnJDihanjaBqOIMqm5jExAoDEhMkoWfAv3Ood5h6Muiyc26UMX22YLrFvQiA5UkpvFEQdx7uUcvGxVdnOgXyunwG7s6Z7ok0FisGIHbbxnz+9toJaQvNAvswZuXgVvJXQ1UwRWEhbcyRlV8TpFQ8MlA4mRLAzWJuqfBYNbttFPkfUDF0dNW+gDY7aQar+r3BuDPCdJdW1Jr5lYXWM3zWmG/Ed/+o8gjIZKN2FhCHJD6dEMhnbjZ0FyOK5wBG0TcUjsB+IfADl9bXeQmtXdF/5xVtDBk6Lbv3DcL/fKOWIEtV14oJ4UQEo4un5/07cYhFpIRRqAnNolUTvhKGs40m1f/t+SlnkLyX+rX2Bx0xSvVKCB9rxyLoK0NA3ahtV6xvSjUhCKe+KPOubYQ6CK2rzE6MZ/3xfm44uNFD9WypDQ2Fa6DqnSeZeRO0qKY2wZaXgd9m4Wk4ZdTv4X+4WspF++HYGfLjcEo7uJ5wrvID6xYoAVNodLMDye4+kkBC21Sq2BHAdz4jYzWqVOCVvYIe1sM9N8x4SfTYedLdpbZsIaDuT57AmsrjWYOW78u/OXjyV8Lpp8weA1B7tQj1qMXK8LxlkWGTR4NZGa88wMKPTsHZfiuwFfIAWpbxh+cwcuy300Cm9EH8ZM0NSOzhJkW/d79j98548yfptlzDdy4tDak3yhMjTo8KLMmXl3tOodFbyeysLQ/e3nfM3jU+H4Pa8smIyRDKBZ9vc5ApRyCxp12onkgE6OHwhau3nq3Be1L2wJdIHwHIetq5jYIdfTAvrdCPIOhFAIEHS2wwXLde91X4iHQT+SFBkKoN3C5Za8fVr7yi9PhNv2qhkjFHstD5HDcV3L91jX0VArU39Q/QtiI6gdCkoIndqJCS0sPPpssRRKKTESMVcptEhfFIqk+knJZuyidTa5MeCMgXZg2N+UDyplqVhM/W3huiUJQ+ssoRl0Wc+iTKV8h5rtNxt1ce4kGM/zVu/81s4/huH+lQtwSLfCza/CbDS8wz+LutzGhuTr/UTDaNB9RPeT5+JBA7/qHXgUKWTQA80nHV2vRCtcEMiopAQwiHzeyLHoxsn938DeD4kclK6817n103f8mazQUYxrn5XzkGzB2lI5n7Bq5JQNjRjJr6Ou4D3BTYLgt9EcFcHmSUkmoWPcixN5X7uq95MfvwgjlYnfWs3WXSZD0oX7FsZZ+5OiH2OGomdx6XDH3VPc583ylKh8Z19cNpif/Gd1oFLhKzhZNkZk9EVavwcG3mGv2RMqTNL9L2w9bxjhm7JWDuT0FdXPmUSGsYVAN1E7RSkxoPm5TqFw0mY0v1Ri3LDnLFZkIyzEtosWts9XurquWJKxguZekNVbSj90mo59C5yYq72ZUSOoG5V00DR1VUDfva99ttqQxb0QiDC2Xhbj6bEqLFnGig8GhB0KK3XbJTwdP5xHwYnCymrZ30xEs3W9fNc295I3HerN+JF/hVXZIz9b7c7OTTJCdo8rc3Lehmpbmpi3BzF0tLk1v8ci8hdECDT+eJvfnk61CeeZ5Gx8SZdtUPQfFbIq1xn4H4GlbhQl6RD7dJ/QTDRfYyeyy/L0QHfJgyc+tjMBPrh9tFZ2R0AKQ97T0E07u2T5u7OPIqnAkojnQnyzawSiCMGmFwrdgQA7Kt+QGqCO7uS6eeEeHwdjrmtz27v4JbdzSQ5BguWAg3ujlgO+2YBxymjm0Sz55Byln3PvTGG5zGbrlYbnZExZt21S4cNEPoPcDvZ95XaBXYqQnakKdHb3B5jEou67H5eH7Vc63TAXwrTbtKYKZ6rnhqBr+ZwzzFnUV77UoyRH8k4/v9A1MwhS3NQZD2lS/lcBDYTeUIxTA2dHRd2e3GgqOuW8BrmQRN78IKu+/zX/BnV9lsU9TEdqxuIyFfghe9DiKH7lBtqOsQEA4Xt684V48P7oRmvQhnkTLJJUxw8JkPUO/GrwHLVwrXsyj7JfHZfNGHgV87Ljhr9LUZnNCE+Cyks6YwF73hYNSMeXEJxRz0nnixy8BKomkehrAaPX/HGvmqI1d4eNW6E7pvHE5VUx1fw0qLVX9Kry5nSiKJE9+l1EZozkcACTdl6Py8d03XkQCWktvoQ7mc7jrPqpNOgr34jjIbPWEln5Lcx9PkzP5w55q8bvwoRfFX+K6XU893dl4q64Dgrsw1gmS9VlUbNXTg16uXYE8+J7mVCPltXrLchifzk3PZnKyczEMff99dh1TnDRc8Ym2GHRyIpCR/9KyAdOMOmaiCgLiUPpvIT+cUKlTXlmo3a383X2uNpa32JLEbkOAQ62gUgn5sNQkK9UzsFS9ZB3XufEs9g7AR3urgVRmA4cvhgZFzNubjYlmA328pGDkhtdCTSwY3oJTvWNodL0EBQci9NGF21pl+hWxzuqhu54+WfSOir67stu7fSAIIJzbuHUOmDlzQgOe82M9fPmOUzvNAkgGq8gPUcNEycDt1Q4dLX6FDS3A9SSJtMerg5hfxPNkvHtahJILD77l0sSBe/Tn7ulILNI7uWMWojQe0vfVtIUeGHIZ1x+jc9Vvaj+jI8k9GL+FDdKXPNHGUArRdkCFDkI+mTpwJPEmA+mVyU7v5p1sI9kIXriU77UFYPZEqv8IXCCOe8BWgeyk63c+nDSVeUKnNkSRhC4yo6/m2Lo9iilu54rdvqgwZiEIbE9soBLLCZe3fqIpie2w2kXj/yJN6gToUwbE8Y+kKmW0eAM1hXz8mcl47QlVessTTS8JRiv+KSm/CY2lg67uFQ6lh41I55nTPTsGqYRyWy0J8cAtku1JfoQF4puBCp2dsqglGcf6L0pYqJ2GKB6Q6b3LmDxrGRyk9Axpbed9Ap9axQnDoihR6G7CSuNNlcMFsJ+aPAkbtVuGVOw2kj0sRAifTR484pCED2Z2L6m/b35eTSe50KB3qB1TAvb1FTCpFDuEX+2y1bSHlT3UVsWTSznfNkT8iFCAYFgRIi9pFqk9uBb+Pt4jovxfPz+Fh1A1Ive/u9ufgZ05XkJ2AtHsfF2zd5s6fyTXd7hEpH1IT8va3TxAWr3xfYkaciKw+A73yGyEh5EmtN8UL7zEK4pJRdyiO1JSAYxHCvZ+m88tnK/sOeV/1AiO0N4tLrJPA7Zl9DVQqtxfYc584XsdiyWo1yQmIY0K4SqDiTR2oOqVvr9MsSXkqwUOd4tJTt2zdIjvmPd1AVipZLgJr5XrOFt1IaqKquAvlhAnaP4NgoS59axXtl6WSSb+16YB3CD8s3Jckz3tQPbafHgooDVagLLk0snLD1OrNGQ6yX8WJHIzPgS1ySJSV2ipPZV1zqr16JGrf08qJHCBfHd/9TTBV6Q8EAi0RbnLn1hXVB8yRC/VIVN8vMk6D+KlHEh69N7XNqQ4fk5sMHRIAaiIpKh2m5cs88gypWl8Eh2kUZtp6ZCorsAZ4MkfwxcmKNqXC2g8o3ek5BsLIX5sCvEHJ7JNFKvqCB1KborcQXLb1IvHDFWx7WIhnGYIXUmvGQ8ab5tHVt/JfLwf2GZMHBx1zFpkzNFMRXtNcb731VsFxNnO20aZsPXszhjvSXTSscPh8j+CVjOeYITuHA8zmdBUCd5FLUC0WLhBf/GRDUAgFftxFbZxIkJ7Pc2qtKO83lg9lv1+MYB32o1bKcEMo4Ih8QhAYFXRB/r7rkpyt+RuE1oxJdUNHYh2h790koRbnMNBAQ2HJ5vLiNf4Q86dfdgY0X16hR6f/nZa8vtjl/788hOMHWET5C6qDBAGWguXBAaeWG7b8ChctkexonaAavsXzrvHfWxvogLsA69PUkLyCdqc38Obm7RHdZ77JPQ4g7IlXDyizbqe7gg+F1EkJ6mZBMjCZp+abJ8hKFEN6n4eJx2zOQmz62hUsvyKqSQmAkjqnvnKvfD6frMlm4WEz92hwC/DZBF0a+auvwEoy1/uB1MGmOxyKEu3o1KRDFqnMRWIzzQ/HyNrzRv5wL9m0HgVipb3QagkQ8m7ih6EwGGnTpVG5kTRfyl15CmfgRtG7E8N21oINtxlYkySNljPdPdP9SOB7lILjlCOOR1bGSM5CsGRIrtaorVttZX9Pjbn15/ghX+VjoOXd0Qvk5K4i9tHQ3AS7hBRlb3YXHGTcrikRAFo0Ua/GP0WJR9zdg6f+AUVrCRFL5QP0TpXnYCoMCrcJO9L2k80wOtvpauem0OHbH6POgWADA/QYpmDveQ9IsNmuQE4KcSj5Cj/9aXf3Zc63v7Wtkv9b6mAolnj20bGVJDTUIUOKEDchAu2zMQiH7P5eQYqihE/W4rPnolFjl86gWhtfLeQYHr8dyOCI207vHO3IhXIK+2Bc3/aA4nC3IHyv0mrJDHWpTPz/QOyVagGncOkyQ8gJI7Pd2tDHcFBDQTVazH455yuVQHftj3y+b6LedkpbPhpw6WUeUdfw3lVA8iw2OqqatM0BpcmNDiITbYQekxq+LL10xx/rwAR3+tvPs14ULUEGcYxjYvz/0Z4aa+Q9yF9LLq9bl0quBTfW2RgTzAedXwn70ktbXfSTYz/fIHO/N/3pivsw+k2rr8KiUY6f0Tkdnyma3S792rtSdKptQlEy4J45hxeTwg0TIhB4xGbkyF1jRJ+PbqfnpzvHv6fU+GKB79tPLe7nFSSrSnYsaZMWwvOBM/ReSQ5CkQE7+qBUf33uuMYDkgUAnjQfO8rfaKisf9MNxQ21GUSZwyq1tbV7FCo3VkCKS/ikUxeoWsEL89Q2vbITBGYQZVDbdeP5obQItGvJgYkQrvb9FyNIK7x1u+6ZgG5N/Tb5DTqVuch4qDTqcic3gamTg6tfpYotoOmL0E2BuVkn96xmbXwB3ykes1jo/fCgna0/w/7nSqeqebUYlvkI1u35DJl2y8TJburkrLha1w/+zhrGKShFUU9zZT2WuCZ0l1VY1Si8W0dHYrZLb0GHZnif95cVKdkEEbko/jOlw01tCP6bdTcWizGS1C1HbRl08gOrla7r0oDQNrJDM4KCR792gOqurkXqmzNWYFAHGLJ4S0cc+bjIht9hLV/YIIl+DpzusRVTVdirsdJvG4kqClImuXdllTESslKDK7t/aCrTfplGkXgHSHItv0lWIFmmmK46Pl0uv/Cm7ffZF+QpkZ3v/BbsAKq97gwvDf5xQ9SDFNu+9lCLPrD0SlDiDxgYQqMLvegtUZbmFN9HaZ9xIxLJCWw98gvBuIkfGgIAkSjntHrqggWvSElpvP/OXe23N2KGQ1Ow3Fu9OWXnb58evVTeVPloMfx0yvn04H0i/ecTAIXEzbMbiEE0u0Gouu5i8TUKmURWX6Ty1H+znswpAbBfQF72n/Mym118mU757SEZnsT0RPf5VaO72ub/qZ4/D6Qo7cqpDK4Gg1tWWouMZ1a2hd2CuhfJuYNzN0q2ZwpSaSSFPauxEE/0bUC5TXFhBt/5xshNBsawRW1UTV+RQ6Tl+u2qVq/F/nf2EcKlIh1SYjr2CnNc3gySrvV/REop5CTZvJkP6IWF5TgCjquU1kgzQ8pWovXU+kJlSY9WIpgWkpzV7/cIvZf9/MPQSzESWd8btd2x6su4SzyWBDAs9t9MXAFa3y0iOJyuXfjKR+bL9fN2mi+ZhjBQg/83/E3px9XUBxBAgjZ0+cwHK0jyUWjce6Plhlaal9MjmDki8jsPWyMYd4WAqGMX+aastjW97Bbi5CNLrUPnWzp9zMsLg5hDO6djbuNcVSEGLjLv9BLARGbcCWBXJ8osqhnj/O4OzHNH5JMlVlsxHKI9LbBkJ9ERhPrZSFST8xKKBfH/+TNShscZW3E5UIWkWrgRFfEVUk5Omi+ANp5jMok3rvLPozCkqYYbrEDaxkxJcvW42cIJqA5l9YdUr/L4ANnWdVRkoinUKc6YthNCb86xzae4zC4YfMb2zv8erT4LtUCg2W8z8pn+G7+9VrVmvm/kU/nCePBMyooE21gaQ9h3/pk1MNDKn+cESbGSODG2LodIbhsFUP3LQVtr0EjktiVTRv7U9nUD9RxYXRy/tP3LFi/VqxQ3oI9sIH3fRsa909Zl7f43Gdz2JC6lKZHXimU5chN+Xik2yyCyWvphB4p5+h5y2KVZ0cxD76OqC7P8+9x5iOqhK+5yk/cO/DLxQfmhcVGM6t6THWZArqBGBeb5u6TIm7Jjp4bCCOCHe1thsqrpDce4Bezr9ssvbpdd9fvDY9LyCUYhqFMtpLWi0PZcN4m9Q5vFEsvNmLsc7Fu6NQwC6x6zbzRJ7VLo+Zth0uGYmJevapyzsxjYXKToA5qsWoRstfwlsgRuKfKqy/ndUKnU0K4Oxs52Up3ope9lDCTjjV3McrO4eSD7cuag0CHH3AFXOG7OHBrO5H48AmW2UIWGpOF9i5pcZNeiHq6wTE+XnRtHH4VAUTTTBjXWHZWetyvQQEZvYUYI4+gHnI54o3BfoYHflm27a8Aq0S6DtOuSWOtjuXuiTWilXjA3weC8hX5twCH9Z6zqe0ihV2tRcKCKbKvDxYn7iOGteA41n0WLBVP+dbBq0XBIVd6FOxI5r9INIo/W6VFq5ZNQeTBTPp1KI419AlIew6CnnJFfPRVhZRM/Eiy3K+sqznVRoAjwEQA4YF8spcljvSDL8K5prrbpfwUiRNjWj+IZm+22Qk2HKuHwgXJClEZNR285kxmx3s+1vuQFHqHwsoBONiF354vgZALlI5uqCYIomG9b+zbe9UgIU0tyLAjXcOwmDtmDzI0Por9mi+2OgDXKu7HAnzLPsF4oVhLHA7B6LoI4LiDBMMdEEK9lrknEVy64WE9Fv7gMggwfiYIJMjkGdA0UQgPunMi6K2usCj86Zpj8A+cUf2tTB6YUJBONPqNkpBTclZnW6MHOn19TXM3h/aIbkC0LuQ5DUZFgRl8JN/0MgoN/CMcRiAI2e4cQSiRIxV3u9kmvP66CQPUaHm6etBTHCb2YVlItJjmGZyDBMaujn8bc15agL3tZUU16tbDEJ+12nWhP/orSQ1mDGDPtNnFgnswyfb7OD5JLptSxZDt8/VMZEl2K0pYkpKnwgS/86eSwJ4LVPRoXO3naIIj1CjOgODwgKkUDuE+EUfpwbR0Wgy6FBoF8oCrYoY/Y0t7eyRgEnBYfYeGnhxwR2xEfPKI48bke4GcyhyzwpIY8fzMDEwXWZmCj2K6Pw/sXM1xK38KMv6zNU8w3jUl/SAze+Q7vM0gW381HKyLiYpql5lRVeMKBDLRNfbLkawc0XCWihEkxdbqebWkoKM/KeNRce6zU26s9usa9aWhFrB5GR9h6+XRZoZ3CySj3sJ7ruHg3gQ0R9/tPOxY6XKavWcF97oSlYonrPTFdd1S8On6elhZEppqTvY7PL8MPvc/KgvPlX0fBnqt/hyAqobNWAQdgrOcacCBr6TrKEMmZRomTjuBDztVMcNCUaoErcKKs+VF9Gr9B5Q+UsXEiqleTCq+TCpYnP9kQXMFFl15ceppurkkbOc3p1Hauw2XMvBShyWV8E5TS9pE461nqL8/EqjgQ5NASubhRn1yj9tbx4YptcMlslLUtazY9Wqst/64pR/oFK0TZDEe2+0X+9leQ9GW10TeIT8V5Ny+XWePKtywLEBi27cUXX7eykdW52Z1AbfD1DzJPvmnpgdUIAQhIZsB/8Yj+hECkJIV3CFvzqhk0Mn3HVfIJMGKuXwkerUpiZnS4dDMIV6Ch00KFBL5FGK+GXXnU/08WhkAZEgNXAJ0xKSpxO5ByASJXy1wmEf1B7qFdOUCRl/UnxkfZCqqT0zbPo2SvNUakPQPI10QS70o7h4Fe7Z3FxnZszFC7zsNHFVxu41JU+L9F7H6Ce6b/njaTTdryWbLIE8zbrPbX6wcEhg+3sSdqlxvpV1wIDrzZDg+jjrf0Z+4QHFX6yxG+4A0atCtQUfwE4iYD3X6AV7K4ukx8lCyp7STDv2BdC3BXWYC0dCMeUBuYJ9nmw8cFTWbGV65REqEZugrpaV2dy7CrffVwu8M5pqsRdmrns+EfSPfzRjPVS9nOOv2LeQhblfUXx0fwqVrd6AygHX4Rm1ryM86AFmIfQHmMA//fmpAyejaAnXL+kr2tqkgc7uAw3PFkfZxuc076okQrM70TrDsdZ4ZzGboR+LWs8cGE3oQRoXaTayD9rAMrevPgzzOw7KuKkiCy/b0nc9M1oyHoHrYAeyQXizEk2T8ae2RShoprK4cCqwtx1WINFfY2d45cC/ui4XFHYl/lSTbqDWiPJ5aLtAU/lXkUeSQLjKFBW/RjkbApfcVKikkZcrDtZtFSIsbqaFt2aKmuAD1jPHZ3qv7iKhM8B4IJOFfhBgX9XxS5Apa5V2YcTroymwOPVTlw3zanYg01H3eIoL99vEDaxKPNFr5YN1ZehtuGq9xfJ1KJr9nbp4MujXUwFeLT0nL9WGUfbbUofmOx4ocLHi71wa8WJyKhbj/i9eO4yzL6WVDtBE+gczK6Axqm2oCfG8KJrUNVT7fG0bWZcRmo07gCTtXwkFud/LJGII+5pW7/5d4jN3/ojohIbA1Lk5aA/LHRbNquEzY9pOo/NQSACng6fxF0jYRh2J0keEtjT+I1KE8QutPdwWJRq4gsYv38ptoB2WOamBU0C9DUZ/syI+OQjSC2riy1JAS0WEoucsWE+n6QcmMoY2uuZoHrb56JUq6dc/hkShQw38ohRir75KiJYM3jKQo9UuAc+jz1LbLq9VVwt4lAMWVFEiu/JvKx2h1L88FTMKaeDkHDynIhX6lpVdx/zogbTsFNIhQ6P10gVpjWzkIRz9j0/5c9pkeO7LyZuxPRQ+83b1EXP1ZCJSm7stpn37HC+H7EVRMVeSQUzln+Qm8HuN5hpo16axrf9CYa+mYyubxMjp+2dtpOPktnqeF7bFiUyGNgHbLLmBBVgy9ljiyLAYQ8u44ZS7KvUfABIvCoVJha1O4uwVqumxA3YDvQ3/w45BQI3h/sbd3FoC6v2Sk/nbHjMEhCFd6c2oC5AWvdFJWr+vULgPlvr5Nhjr5PSKb4PpKje25a0Hs/1PzKoEALkg8UP1t9RLLhvLtijpdyKDQJtupNuDFJpa09UZcGO3iMKH7QCs+fdNzkW9zSgRLKuZQVeYtRu8hlYCtyWhZYsWqQdT1MmK9emUtiKBez6VF9ByBhbQiUsSmw33sW2VJVej9PKxB0ywUBBFhp8jgciI/qC9MvHpsgAn+zs+tzqUOnjBjWPHeQut8LWASMrf6Yp0y5XQGVa4RyHPlGkH96Th/K498dpiEb5ERJ5/NKBF0U8iaXko2DQjeMV1WcxthpxkmdXhAtpHVU0LpXeNzVzlXfByRJ7b12ow+DTqQXbLH4hGwjrywGnrZYxa/W0S9HLBnGX88TvgkqQPUx+ePQcEA1y0fRkscz1IW1EAzAk+Szt3LwHGS1UBRDWiOjxg5OGc7u33rvv0fu9RdY2j2952ieQe5Cq4c1Mgvr0gGV1/DdBqdy2I7xEcMZyvP3QGV4O42xXz4sK3lwbXC6Y7U/T6W+a5X9itpVON0H/d6ohYNzNZseCIgyWJLMzSoJ8vLfToL+fpeLg6XD3UVzBtTvTVOD2f6b9GfaLqYRbfCtGIwTd7FOXh0/iXkvPZaAFj0p03BqspdLEYyrvQn4maennOEzPxNQY/SpGgf03ccZ314Qm8v0ul/l/hUZCiBcO2aPeXlclzWcyyMTGD5eAS/YeY1jBaKFnKh+7IuOCvG2Oe4W2mhlGBIx50tBOmY+DlI89hGxLUV1OLJfy4Z2qkbKKJSvjd4oufPJfWetEwGBePrRk2tDnifoIAa6BuA0F0z7/MNOUoUkrCSE0hdQKJElbEMa1iDW4F5EjjjLjFAYf2bcuqrcPt3c5naWjHqzpfmk2cZQZaAmd8hp/WMt8RB6oMgfzsz/bxHjCxcPCR0vFw8HqOsJbqjxaadmK3s0OaO93YkSxuQg6Lp/FIZNhFpuMQjiECBLh1lgwPFMhaipHHH6szUbpjG4G1XX/I+nISfXnEpqyK52Z9cHzLStbP0g+l+Lrc9cx1wzdhkeb1IjFLzASuZc7l92BKiCBjV8vbcfmgt/AG/J3WWTpT/j54hmoDTObTHlKOfBAxv4/zLamp4h4Kandq2xuBza1ZRPgiQi7iIE8kvBmICSV/PTmTIitmxTvbcP2nEGRLL81z9aUy+VIBTyHwIyxoVlLmKgeXNLU4rF45SgHXh2bOCEFNjYZ4+DIxlp/CD6dmcJiLQp2C/dK7HEBd70R6aMM+Kj7J6IstEQzr3KLeDqUMtLGMRgFM9fce3qMVgGoVCBpmAmGfD9lAEDh1gB0u4ruZiACWRPc9v4KuWizp9TYEJj5YGevWvUfwHFG3eX8ZDotSFk4/ZQj9Wp64J6vfUSYto3JqinKloQp+NE194HD3aPAY4wCCOgqzhixyRtoBnnh/Rl4PTnnS7b1Uk6K7oDebuv+Gny4Cyx/CHpCgIHkog9wdqAUB1omRg1fgij21j+b5hrWnpTX7B1mXbRwoEkUKD45xfLx0UE6EC527W2teNysf6sXfAwiQrZnx27qOdpJ57dBLBXiiwiJ0xlZglLxkxpC/qo/GYyyVeq80RT3WCqlZXgFEUXTz9XFCXFF54IQmRrUXuC8TD+WPE3dW7NB1w8dz8ae0hi2OkqaxZhyFi8i0zxYEXoa01Knhktob9GLzNPjYUKUIhQf43M7CjzKw04jkelXDoCMQKUGJkJI8jLdtWpsYbLPRoJtyGsO0K7rrekIzRP5qkk3WOzRuZwskW5Z06n/njQ6E2+nuOxuwrcy6dd3ruQz2S0ygaBep7izJw3Q9PxZWnQQfQL+lYBRu/8b02/6mQj1g8HlhjwTCaUmHQ0GCs8Zed/7OwBLED2Mij41rQXg1KeUcMoEgKWsXRc7gQI4ChzCgd0Q/L/wXd6C4A/+viYGdaL1xoyfInlzhsCoOsZCJ4dVvyU0qC0BJWgWcSpK6tNG+gFpDLRSGvaNWXWhMaGWhqj4Jki85C5kVFQi6Zx8tkFSDdlEqnB1XNGbTluq9U4+yveLBIyAVVJ34u+MMRBSr0XV/aZhDdF2xAAYBn4x6bfcdBymK97humW2kYWY7lH/kRZVD1MuU/wKd2USUfs81ukHPpOj2ivbSvh2axL9X7hXhQrb4BzqssYmutGr6Nv2ApDHPVsGOYC8q25WVcADStY7J8W/tNUsF2dm/RdYF8S+qFCYBbWd5FENVoXzAXs+eQabcxapNflnjcayK/aodJEzFaKhlp3rQJgVSEOTzfRSaHSKbdwcsbQhjUMn/K+H2Ji2JPCnb40iAMYkZUhVsRbzc/OoXGlGZXpN9Ih5+QIUYy0CPmNhEn0oPdBeJPG+FEvI5T0YIf6ah6krZMA3E7UI083DR6yBhe8EzIz+aeRn2jIW0ooVclISrGkVz8UcMwid07FFkaHux573jvIdE5TqsgXc5Z3BvoL9giB9mf50mf71HLP2nsxAVA1paptpORLfQZOKtdKhj2Q8lT8Bk4/2Y15Fzm3S8G70gn44hvb6tzyi2mwxHu24NQI1rgPpgrxRPhF0iGH5JOp4A8Zu8Qhnm4lIURaYW5/DmbIJHS+tGHcL7evMHqLQNyRD5dILuCZ/z/QsDwixzFkhvWFe8q6e4cE/HC8ZiyC8SvS15HfL6hjj0TJiecWCbowizJEF6dLpASBlOlE0rzIjEmrjJLFDKCysQyMBaFbGk5paDctFniCwAdTMk7LotBS3xRS4t6IXfJ91soDU4WQzcbO1rb7KqpaH84Ip5H4wPDV/Cg6X+rh2+EFq4F7YxWTh8KH7ZGG9lLzcyh43qI2LXisNKNXu4lQ/L/wA59ZYlUDMc72iUoByR6TMGgyIkabGZta6pL02idxcPPFlrlu3DfMiToFKFPj+STvzdp3c2TyUcxUsyCsLNM9zC6fuBGLBNlwmmfFxHu1W+NaqLMPervGww0D4PR48SkbQPUEkBKPMe5bBl1jFtjXj0bXkCbU6KBX+O8DcoBgYbjd5u0Rbl2mqJoAn3JhOmMi/uqaWCzxTHY2rrka0E0Q3s97XBtMP8+aHrUTuz3RBtHGjkAErvNgdsTEMvfJzuRfE3fZ97j2XG3nO8Pal3vWA1bVz5626QO92Jm+apLKn2hJu4xkjFhO0AhOwnkgYaw2RNH6ABExsjU4Yg1DmFD1mQKMM5S2TRMSgDss5XrLeUiJgFq4q1HKD/lnzeKRBryhJgjdIOtMubLn/ET7fwvACbheADaO7LiyUAitMC/2BLI9/y52+zuYy91BhcNX64ZgWbHeohK+I7uUrV3ycgv2DONIS8wubWABgJBcrUoojAPcRIfFlUYTi6V6k1LkR7u10c5tNwQFMwIKdgKmKhjrmKHN4Mn+2bOq/V+d/8rbNuYuZ5eZuYghw8sJtV7em1ks6dCHC0euu7UnnV7X8o0X4+kTzG8xkacWO/P98ercfs8Cf0QONrR/0fWPDy2xmV3jKJfaMlfvPQroJ2piqrgrhl5V7qT8rgLnxdZSpM+xRankL2zXCKf3RgxRZKVHsaOH0rT2doJxvB+ju6sZldk9j1z/3F8/q7QcpYN/29sCkV+iVCTVH7JWwbKgnOmmug8yTFnoo6+YBUNg4PE8ET2JehSz52k2tWRuoS8HQc5Y3eEReEREgafYfttHQnVUG0R572O0DyIy8htsDJVSnhqCMh243JmRCRTCtW/95NnVmotEASYoaiMUPZyjkEEdjHgE5nn0RE2Ryr9lWr4UiCF0G4WTOlyBo1Lo2XmdQEEoq54dtP+lAUSHZMdqHEybEkNvcgt4lmyfGiC2T4+T+g9rJINJ32fwhuIARyWgJN763I0zgbX/OcOcSqnHDZJCdjuq4luQzbWF6zHf2uJn67g+l8BSY3CQOSa8gbH7H/7T+R3HS/i1sz+WTXG0UFyDQKeJWDkgVmMJZ3Z6BenN0bPRi+1Aj0VlSbDlW81KB+R1oUN6yv4LFBtbS2FZ+LOhJN4hcmHWifDv9r2L2dygmx1KHkL481pQqfqYRQJcTd2N++wi6s983eMQ/PiedTxffR+lPE2pCZ3mmXnE6lHZVV78jhwFMgOlXspwS/s24MlGGOXRiL7VnAMhjw/xETxmLybCTwUt4kul63CUQ6yMOeC90MngqeSg9CoHYjLt8ONFVb/J4HjWsPN7OTUjmJqyPV0Sq7MldVPnM2O80AMiuqGL6kBwoDAgci1zV62lK6HnbT5LDm0+Byfo5cpF15Xs6mkAU4MUHlgOUdhKFU48s0PbUvpst3Z9SM+6fhtUo502Dzov6WcUw4IKxOOayIFZf/kaPauN5HHZuytSeMICmZqg7Ql/6RWgq45vftUF/HdRy3UtO8TzCWFcWJcnKBDJ0AiR82iutZsxUXKICvAEG9KeWOKenODMSZlwSR3tWe0EeUAprssgIN8793+idYScFhO2/dVHs0TY8NY87WgLRLhRvivG/TMm1Rfkf5d15tMi7RVQhND1bSu+ETA1oSzgSlAQUVRRqes+3nbgR/RVEpOXHFX0n2vlSHxxcMxqG188t1LohUx1D9jDHmH373AqKDefRwrDrpCsWOYgBOcZfw9Yz1rDOBR32+BWaGh6ntddtwapOKcwDxOhTXI5SrbHqMWCIU62fNe8JKU4/nPq1F1w8/+6054xKVYd0PR/oB7QsTEJ9GBnLT0nJw7amCW9Rl96/YgajuXLIj6r7mdEckoKqRfr5Uexw5Y6kvxXydP4ykgqf/pm+6pjsra7NCIfKzee7jdWhd9u21dA+K2qKlJdU6NTM/1Y9Zz6w64zzAAwd72uOTicrXtYd9+BXfVD8/g3jR3fRFzJ9abRXcLTKaAP6XtbhMSDQpfvh5xSYjIQrWz2140qX7uV89R77/WGKY4hAMacDGETCScSwJqD5vC4jKZYE8JOp7xvQw+WMn/KIRf+WQ+7Ae68K4r36jBH5AnBKYtEskgEbNauWhYTZad10AfjS9TkjUEg7ZPnb1z5zblJ3azMIfSH/aaHJyvU82IytuWxLniaaQ4DXZVV5X/2gh+pgn46viU1GSGAAAHcBe266Kb/d4cHmK1MdoXAyVmuMV/uB8jdEQzV8kgCF9vncL0WAje9vNyy7bBay4dbWuwYnjGOfeRIzKuMDA5UijispOTDQRI12ZXx5FavPRtZBWqGuRULkpFakshBSEAiVp91fNODmLMXWX5xwyRkBXLmH8UiFphywzO51HI7X5Qubs7s9/EyITHghdahhpzors1Tv9dLNKqfpc8NAJ4C60GSK+7m13TI8j3/A1UsryCuCdseGLyHKgkAXfy8zfQuYlTvasUWNX9itXwqV8tbQ2Lypz0zl1Abmrdh6XgF0ixpknLtOZs6oERNgCWyh+/7TGCx3GuJfAJAO3pHTa7MNuoi/cvD+O4miVMqhubkB/SLvYeXAk1alTS/MCDrgPxjV+1K6dETSuRRksAX1oMiLMYq5zv5qdMmvczRrCJMoGdkmcBomJX1+9pg7qeiSjZbgqw0OC5W4zy9A18PQx723DjxwZ3Pg6+rQh2w5T2ZsSrlEpWhcn+uVHd6DwL+zHeDd8hVWy/Rt17gtLZeVxK6frpTV0+3g5N9qBB7lQGzRCsDYX5JfEtF3mMqT2wJE9bl5bD7uLHoLF941yOjjS41CsN6GlP0rOZigvNSQ2xQxswd1lCalPK5jWs8DrI4vaZIK7ixHdrfvWWhS3UmK72nyw4L4Yx7RUYB7dPRGGmgT0aaV3XK/GH7VUkkimatoIH42EUDZcFmIcrpUi2lbeOZZhmlXm2vPYbjhCWF8vTfgO8jocSHjwoVNA6lmq8dUwF5yTCgn0Vhsc7zVjGWIsBQL4hooW9Kle0S+jW9EYUrhUlRyGw6fNr1jvSnC7OWkK5qvwqYGscycUYVfAuAXKQuBwbtHKN9CmL+67h9ykyD3LWIftf2obCz0So18fpBJ/8wta+6Mvyqqxwi+QSwAlcXWseQ7DZ3peftnpmJWRwbYNW+4Y3ix2pt5H+laW5IUyqfRFxmHdvy8hBTCV/TMNit6WBbGDSc0psVIuZGHNz+9nqRYkPPI2W9DIptEvZPO08DjC0y+KhtQUvTINXWC4IIHokRC1Bd0Y0L8MM6JX8BbGZdfzq2lSHVJmMVS43mRv75Eq+/rBJ7BRLDGbJXgD+vSt5E/qrJx3cfqzAMnFYdh7m5myZD7NlFXye1vJuqlAI4BaUUkTvBfAFhV9FhkgR6n5ooJZFXnKQisriJV9d4sUk3p/qzxAG/PjxD6vrrYFkNq3yjo6CizmrK3sp7pauO+g4cAmW2cptWnOi9jiFdIHgE5xgZYSBfdbslMLdiQy7Eb0j61h6rMhR581p5x7sXVq1xQkow5n9wOMOFwpFomT6lx+rUzsWPBYj8dTD4ybwRnUVP5HNHyjCxeBIe/m3EZ+ggBAgqHsuZYW9ZgOX8BGe1VQIuMES/r3hJm/UT+8uk1Ai/DuhCc7SQp2JPyMrKiYuZho0KL3WSPJDfU/nbcMLciTMxdSr4mv1BWEGGsoTpLThbPNwsYZGv45vwfPKSfOFOb3qH59hgkLclqbO60Ce1gZXsvw60xo+HVPL+jOC+Si6oLhjZR67xaZ4QoVrNA8FPXy1BKWLwRlruBi1TIJSdnc5tHqTRyvsw8LDub4iRlBWv7X3JNGyMkRjMwDOxKYz+uPSX3iBkuUX/WB0oUWxnlu7xD+94UpGdBRNAL/oL00sQCV4a6ao1ApeCe8ZfmZGa9hkmIfop3CYRIXe0ZbJMM77d3ndFfHhwzSEGHxhW9ASEFuHlx+2jq9XmmUwPtMELD6vwkngZ7a6ae5cBTWEMuGv8SyJP9TPCSbMAi+jX2NVdIHeMtyb72+XuzNtGeNJULCq+j1mj5SOTgzUHtW6XsyLHO1AK8lMHl5DcOSCWlUUQ4XaDoCYL1fdtfuhUHC2QvOCKXbKWbttMSQhDwMR0L3Lflc+SllQ+iqx6gapdzLcA5OmP7qoFti5nRhNwGOu1tPEouSo68xeIF64S8/ikX+K+JRyoyoM/19OG4unkbwhi7QdA/dzUDFT3FGc4SUuQoqv1Ijqau7JQxbyVzF8b4JZ8LWX2AOU6mh0g8mFufOZAKE/f+FNXhL6U5GcTW3q5kgFsdDuzHHSwzmo4Z+eTyX9pqDY3APwsQovL7d3Q5u2kAe2EcVkuqau/6zmYpnj1/zqF15EDlvA+hSWY2G/IHa4CQOgaBWnPnW531XI7Mvbf0oK8l8YYYVCf5qXfDTP3xzqll5pQpRWq4MFyXAUYQH77yPF+Gwp8i3yWG1LigcO8trluo4wwi1pNeqei7tWplrNvPrp0w4pQz9hkEDPnAaweBzGteGZZ6cLKyoEtGgf1i044Yu+2ZFzS2k+pYuueAI0mwEqdVK7DdR2kP7MTXFUjmARgNJx1cu6P7rA2A60tTcqai+n7oCdNfSQ3bjFipJMI2xLCQxcFRu4dARsCLlDXmbvsvVQNgv5nvZ3q8bCDBQt85YGDMjWCsAAZ5jhdZlS4EeNytjX83zktcW+fzeY3kxyuEBCL/VtfdDRFSHv6FbJ1GDh/BRWvT6MRzrwoOF+lAO5ZgNb4HwtQvstMzzGbBku9itT5REHeOaGt1rJ7ie//4zgjLLOTjmkUdA0BnQCftVV+u+sLHlQ7PiXL1OqdTfFOCjUR2Bcv9rf9jRoBP9eGbgCJudwPnw5QGWYDawQth25dizJwY4wSOSsg3uPxYVut1bjXKNrUTtwK1+PBXU63H8azUq96L+Ls45JRpveDJBDlTg6vEFY85bPf6jBwSVKVWUjEEBcUDTuO47PFJWHdYzwmMENTGJrL1XRMr5QHqH2iSJ2EoMDqwDAGJvohdZQRlU9JSKTUQ/AMRLXSP9cxM0DsehROdJa4723ZRFXB4e7+KAMBkDsFnQn0eCN7HGsJEcYvTMVSGkAPQggSh9tuAZ2WwSL3iNDI1etLU2SeYszsNzQlUVi81RaAA+liBm8BARxVQYWUVwGSxxm3ZN54aT9w/DYC5v6mK+MAH9OzOrNgWGauhG1ijwbNWOmirSizTenXnQOTTvXLsXRYKlZjP3lYKhJrC6aLMMEko+IUxWm805nJLQG7iy0bnuofOZVjCXfnr5mebjO8AqaugSg55hyUWFycu/5nvJy4wqfO3OgoG7UvNCnLxKe9L1XYI2UR0bKhcfDJT02VqHh+SMyXhzVXzQBeHBhZ2cbaqLzsYkvJw5EagYaFaJKpEWsSpApmcfFqQRK4fIJvP1uOM8LpDcls/hbYUnYmclY+5OglXd+HOlCmlMKByFyQ8XQGXFgE5DJ7oKWXdmJuiQ2/Eqdbe1vYKuH/eT9Oc/cZUyR6/aDnkGyEtR+FRyon1VrW3WtAZOt6Ljfw6LdhusQpvJ5dJFtVjrniVtcnTKW0cvsFmvYZ4bXSv68mM8SeECwz7WiVeraWTfQAYyZECUHj6rSEiKT7mjFOJpH+yVLB5ntfC5Nd1tA6h/pA2WzViIrUN5J0m8viU5ubVthazg1zaaiegRv1TEYNFpwmkho2BxD2BMpPxsw1wQJc0W7kBOqlSI6t2JTKSoZ2lqThQ4wcvJlzvqy8Ck7tjhzlhVrsGfJ4HpuDZOEbXPRT2qvm5oEMwB+mMzFNhrpo4v3FRoK3o17nXj9clrnLj+a+pah+M6OXiJ11WR8RERUpjlbk/+OILm+EkncS77NyyhQZe1QklkcZ4hSEURS7m8K7Jnz8TnYV54zgxYZW58dbaEMCll2D/FXbacAGiqpzFNHNbgiQH6BNQtXF+I5QY8LjWLmq0Pg5U69ioS7KDR48sCQPxKBkk9ayVc0hg12hfH+E3HYcahkElR7QhJFefExoOXOlO1TkAB2UfLHDz92um3DN32soJnhLcV33dEKWlkivnWdtS+TJjoC2zjwMz11YXcea2fRCmfjafo3PsuMBXn4j7r6ZEJmpItc46LNPfKRCJWAfH/nw6llik0+hpPFv2B7L+jeTnwuEhr+g63lMP/cEypW7MbIysR/QSZXUvwrm6zXpgrO2J5j3vVOdzYDBHEAhWZvau7qGTfvAB61ZpICv4zaePJG8hJytgd0PiTvdvP0uduLoB5luzzPAmO194h+JFIwwJe1cPTXAM2fveSfcSCajOeD8JWT4EqQ5lPgDExYO1QBtsRtt2+YR7Q5IkNJWmRVUT8qjiPjbyFpPjxbTG69GqEONVS/3rs4iy1x/ne3fDvCWeGsTLi42YbWQ987qlvgAyrLQmQ/moRUbxyViMO2v9Z9c2qih1gViwD2Xn+WRv+DUQLULqNA52pTDYJWOPZvF6FZ6j9oFsrnH3s26pox5iZeO+i29XpmhP2Su9owED7t2v0R2jB+z68+ZY+baY/h+6pN+YkGPoYzjAj1PveaKVcXfduheNVBS6yPxSOS1yrAW+rv567ajnApY5IP94CnMfLr/1ULLyPsgtAsMgWnDD4PJcDvsjkb+My+XPlzid9HZpSpU++Tf6kxQOF8SWBb3uIt4CEY2UW3p4Xy7xBei1erdoYC89rc73F85CEpHnIA6O9pxfM8WkeSnsdwLd94rPiS0wBzgYveey/fpmXUT7aT0kNiBTNd240D2nuA9fHX0ykx7ezDISggaXA9fVnMYHSOD6LJ1d2oICsQyfIuQ6Rp4I67yurSd8IzgdwIKN1y8AGKmJa0VtSfmEyWeGznW1bzZ5xwyPCV6qziYF3yce7KWBhIzxReLPRD40YP8XQ6iNReFMHjQ2GGCC+XB1i9xITciuUODnrHvmab/jXEJWYVgx9hWMIBwYBtYIdSO+5bKMOTUt79fVBEA3br113ZF/rNAupWwPtV3x4iGT0rN/rYgBhE/jmzen8fvasQGRGpc2okBTu7S/S50fcziAUEUz0LQkM1EQuozgEGdTODOabJz11D2wqEWzz5pRnpHCyY6C8WELtwBGUNAUjDyFmNCxmYbJfzKBuarB6KVrEIx0OTqFHJ8+vADSwDICNcp/5H8Ru8v1pNJfJ4Q0Q6vDMfs1TsOND3/gWhdckKMYy2UpMc7GtT8SThqSCM0BFwpgl9MqTL5CluQTn1gMvKUFBr1nioYlBmBazbztmF3JHhZ7OsmmWfpkU/d4KypIk+jForb5ksYB0NUPSdVd2FnJl+7lWLjsvKDybfKvEUoFj9xCf3FV6aPej2t+/S+tlU41xY9A39rikw75glOZ1gqvI2n3eNzjId6ZkMMZ7jjtu55V9z5xc9y1ReujG/hCDQiNqsW9rjZCCF9M10QG5bR5i5fxzyQOmjdATFIibO3GQcBSxm9+ILWnqKK3oUwkBxxFF3DWOAkUfbQ74v0jkilyPDN+B3dcp9IBkOiQmgsDzeVEaXt5p07op/iekxNlgLm2gQhVrpE3Xc/uuId7asTvPr58nIx3Y/OQLDldHJYrJSqXUbjKmM7PjrUmSeuwc8yOFn7i4tu53NrX7ofK5DBL2TESCd3a9B6swWR6VYoj2T3OeedkbLAJyBjQcf3ncVhNPCiv44wq6HTU5qTEa+jnWYoIG2lo7MjiWf0xlPsSEzLF+MQrUB1VAvswZmpCWcEccbvKTqS4p1CoHIOPoxNG41PbzSU2Z4zfREtPYj+ff32tgBj2QljPQjL8JIMfFBPCJEqxDn14zSK+q+Mx3fV6tT4lWuEXtmKIh3duI/PGJPC9GhHHoywiCH+bslUP+emfPhXQiXqAUB5aZXaGB8duDlX3BUxQb36Yh8R9W9kK0aieilr/dVvaGYx8Pnb5AK27PK6BnzaW0URLZVpfZZnvjnW+sN/GEqLW3iUXDgG/+YlSsx9F49ODiUCmSmQxQUKsObReTOEgmU04vW5IHS3TNubrpEZQEAI362jwhQlvuqKZNQ5r9PAsBBUj0344WFLVF8OZ1n583hUaXlbjLqETloqrx+sbV29dkXh9jTaeVGEPVpRNGljCX3eary3Nz+lX9VegecXeA5hxkVT6Z2Gih0aAtbzanyCaA4DpJ98xfaGvIq5hRkqywnHOuRPoLqpz5QBMLiCjsT6C2G2FP13BsCdxoexENHUtTeGHHJaF1y4gzlQCYQnkSX973kRU5O00MT8jBgfRNIXDplqEvc7xn1JGHF0msSGPQ88+ydLvWju6SBM6P8eQNt7wVZTvhlNwNRtxNmTDWqxofibYhPxTxZEyF3IqGh9sxmPI7CxUT0mzS26GtFpemVc6DCt6uM5akbl72iMIH6FAjsrtAqn+iTatp/fQWkJbgVlZJawiWkxee0p8N4Rj9N3zt21ggIdi0mB2yOtHaWRAKRBur0N5pm9n8SAP24KL3HJT5cj/afIswgSGEZ19OIwMqfoiSuXqIQcyoSnu3pXKdNJZkjG0NsTdlRo/Tf7m3croOg69jrD2xqh9Y2wVh6f+O891N7UrQDfK1cr1Ytp1k4wLzF+o5fmPSCtpIfy9EGMyPPDxB0Sngp0ejBna41cDn/Fzvcz8PFtsrFW3arj9TtkK0KIQvIKwjOBTnH+offaAPy9b3tsE0/RFu4luJS6xat++iADSW/MbjrpE6BZCfUPriFx1riFkS+HJ9qaAhB9LVhdLygpbOASn3OyuSRqP+wK/enHb7eIom4Y+Y70GAVL2HRzoONVZaNJYThwMJ/xhiX9BFNKdR0FIQCDg5lEXvbd4QpvEQYgO/1MelJrdjmcNTXfWPQs/q2GkStQmxrVZk+PuteIAwc7XZ4/lbpq/ky3D877sc7pzMQ5IN7BcZpwOIvcMCXWWaPfFTm9VemwFP3fIGDoJY3I2rp3Ngp9sj0XYZ+dl6F6XJVUr11/xg2N7VmxSf/rwfZ/dEjlEeeMp83lZ926XaWBK66l1mrgEHEwIqSGdKIRuyhwzBIYA6qiv+XVa+0TWsf7fqlcH/iv6aPbS6/5YY4xTP3vNArGGE4eQxFRmvJ+LJHcb5vMPvWbkVc2eJTFKPEIkSQgRevlgKLNt9iBivqvQi0ig77G0kgzm3kFq51Ynz8F3lyuf+ZathuLYlqTPxdoCOpeXgH+gXrPBlMvlsEGAD3rLDqsjAc6SLhdr5xpls4V/qw2V/NBIWNXDPApuISszLG/2iitRjYJ72AtQgaDxEVA31xIaDQHHoBDHFj6lT2NSGSmAbguN4RyWjCZYynJYisMgt7Ydrumh+80cQMpu3DyzL0hc6ZD7wlvhgYjQuWQO5sDoirr5JZe2MaKsOFEw7EQj3iAw4+GRzrlkisibLOF7y+Gf4Y0M1lV+RJ0X2FxeFodDfJ/QCsSmfbdtosv+UZiJA/3RV2wtSGXw0VsX4cmit1UMwyZ8/qKJHDkJ3EarxUEzetXgzhI1Y6l0SWem+XUlYNldlX2cVaj71tPN9OEj2XN62QgKQtEYpGc2Aml2EFlUTeZH//QXxCoQFvyS1jSMh7noJ7JIW31UMebMmztGFOxroiL92wY182Eid2yil/yqHcjTJeaeqQp5YA32JMpTWvn5MlN5ZrnXuhAccvHZxkcuzZvJxcieA7yu7eTnRRJC5vxiMEd467KKgWyfgW5H2avS2AR1OgA9UfR5IOYJsC5ivvLp4vHXW22j4YMV9UEU6cFKQJMRTkavocBMRh26qqPO1EcOCjT/MEmSqxqRorsjbgalPI8aG9OlAxlUVVp7syNVBMqWoBh1h7cnl3DQ0RVXodAvILS+KNhIQCZ/LAzaXTUZ1qdeMgfslWsL/9l/9MVgAu8rPNmP4rPckY6F4wKCIjL99wOZf9cwNFjCL63rFXO4/9b826cXiw6zEnoyVGoZXWtBv4C9AjzU8y8b09MZLCL9853HP8h5Na7wiw8wNiXzclJuAFfcaDA10cMXbmPGAaysa2apM1CuaYrAInYPNX0zYUBXjiZHCNCGHl9tVouZj1MT+lul/Au5Pqkpbk+i9KzCpfCzcb5lGQ8WBMnN/4JwvxzEMqpHoFxCqPVrOIpTCOWxr2Yn/nuc/a+LK2DqWfsJgPAr6K6zU14RD6bXI3Dv9czg6nzZWl3W69+9imAOhrqIHecJ1o3rrj91CXuv7gBVoj62EoUAdY7Ga9NPnpbYO2ZU3ueBD0pbo55zEnUSVCm8ah239jJe8DUrfdlWqSXQHRc2id1g6Or/13Wk4SKqlQzzQua9iiq2OZM4Mcw7Q2CkvUZxy1SBgUsXvT2VZcj++6wRvzqASbEleUb01Tj8QDND+xjm5gPRa3Rv1Ng57EHT8w3itTcxpA9gH78aMXvxdUBTtqNmUZah5ZaiFZpIhGhIZ+sUekU8+n6wXtaOyKbz2EhG2lQ/tib42oF9tfMshQW9VzNWaBbEyKcTutpgj2appPums/pMmvNM/J3QIs3AcpwUtztdCMVpe3niKmIY4sm/9iPez2qXqkNX242zk8yn5jKNE6qQgKDFiF9Vdc7+8Rluw+cMoCllriHq1lTQMBuy/99/1rITUz905L4DvZgxCapimTybjDyVJ4VauWLaAFjc9fXliXpdT2KyLx1GeTdRTf312pI2MjA4BKn1898sDI/BZNUg3d6OLVgBwBVtCp3WXPxa3LK84VLBNU6KbO+rJN4t7PD6V+eupj4xmcc/0cDFav7u1CLbxsmstFq3s5PJQRySoiOrUvr/sT26FWXscQrHiy42GOwx6/msW8T8zdJjR4vzSv1G5JgJnemy2ox5lIWFPSerLORQ39zJmSKwlu5xUJuTxZPKTmICEhbHEzICA3KSeSksyl6WJkLl64GmKMMKaDmeS8sghhKFrzoXibY4VZuxN128CmQrK6eNWh07cAfW1juqk040Ict2Og/csRgKrE4OSk4VmkPCIzvMRzQGNFX/zH2ujfKGZ0skWto9jsNJ681itJJHm5tega5A24HgOjGlZ78jwwu6XBENH9i5FxAK3R65RRL7Ju2Md2iG1SHoaNy9lhcCgXk/1Jj2rN0rr0RD9OGHP2ASy/pkSrEAuq+0LsXjnuk4mMFuVJWTxhq/uwAcgFijmlXUPgQYXGvIVC6KIGIiNiZzB9puqKVrnCyRT2WVFzBneo7Qz1FiimGaH6WtEZrRE55397Sr0eHuJa9NEnKu96VbtC1fck1QC9EAzQCOeIhkLs+7YxOpVgVx4bYrKe6FEK1hgHzCFmM+sD4EyMX4O7HUyR1Bx7jlmXyY7u4qupYQcVXeMujifYUEDaL8LhmuLl0huxIW/7YiIdgkmZmv3Y+HGt9w18OZpgkj5pxmRIw0ytUomuh/DmOexeFXxv0FVYNQlJ0yDd9FLQiXcQyqVJwab3KdIFbGAs7DtUh7Y8qiy0Qe9VCCLaZP5qiIBl8RxON22IeLFISTDKwnE4Isz2ATbOgtQF7vTTJyffwQ9g/A9AKfLIlt87NALiiqu+7F12AKD0VscVAuW5XoPjZhNZ22eYctbwCBMYXpX8ss3elhtwcdqrfA1ESmuWW3f5EyXuvfXyJyZtwX+k/IdY/PyvP1COS9A2jOfm/dowAWe4pOAMvuIWUXERreoP3PWYELkB0rX3L4/cHSqd2xddE+Fc/I76X1N1kN5boRwRw1JVJu1UHS2REponUGejGE1XWQQZal2MRmFp9Qqdbcnx+guJDAwdj1jAktM9ao5f20v9NlIGn1HCl3IeZgcxsPrEDaAeZXmX1xUOJZuYE9rCEDoqHCFebtCPEJjFBqs2h+sk8nCGTUSKKcEYr4S/uooivBwZ6t4mWLI1R+HI29M9Rfhk9tIbJJspAEX0IA5TLmb4/f8A+JfLnpjJeRH8MSOIPm2HurCkvaXhshBKO/v5rAdeBSIO/4HLxhpIcoL8D1axCyOO6YZqKw52IekzcaZMK4sf94z2uNZ2Mk5mu4kzRzbIRUWc6McGl08rGJOeF2uEmLU11voqdVLnJvMCYdKJNhfgxXH+rbgh+phAiUUNdjLxG2ZTmRCmqmo4/eQVxqOaQ+sLb2vetMhdRuqGj3R8iXVHVipKhTNXQ1KU1R/JSMNivZ4y1xE0I66nKvyHF5KA+SBxSL/SE9IXsd4WYG2BzXUvGVf6gxPtXu7qpvST7IdUDuIdAjopWF8pNLIEuF6GPxM7M1adIrUfay4CruLYcnip0qWT/yr3MCXQck+D66/dvUCvKKlQQaFpkf1Yc7lklRqCDPxD4lXJuO3Ds2wNJ1X9a9Hz0mBk30HlgscbMw7tadVJsirYx0nH+3VwmJzYjz4yGGKkH8ppDeGixEIO9l3gF/YZqW9PBA22vW7DTiYjksGxBmv/eMB0OxXqCzNA0XM7OAm76OL2TWflOD1g4nOcT0TIVPJsA6FJHk+/LPUFwPUf86lS1MupwOZFlgX4FC+U1ochN3agSwXq+Kx2V/Y8qQlMusctanHoKp87Lg1sgLsI7Wo8D5GtMyTOj7phgjOeCIYrVKiKTorgSUX7u9Lt43rw6VPN/QTVMVNDNX/HYZDAEDy+l3kEIbeEm0aBOwG6e3mg2mEWd7MovSv7obV1gpVO5gh3/a7oNs03jSUSEsjsOz8fvtM/azWrv42JIl/wRfJllXnStVvKB1AHWMBf9k72CucoK/6Xekk5ejz9w/9hp1qfv2qPaPBEbyJrX0LqrbgEAL+JMd05pOONubsiPzfyUkQvlRHFIMahkx/BbkSXmuzN8bOssFEcchBTjTe9HBm4QgFm6Uzrf3N0yjv/x7xDKJpKWVIYg0NFYoJjxulp4Ma07mLaZZ0hCqJ9FchdBg+d9Ekh1jbaaYI7DQmbNq/uk3OOSoAWnw/Cz8IKSzKVPenb3dI0JulxyZykJvNXB0JHTpCaLH4oFWf7O2rogSMpN9ekPfr27mrRK4cNk4TrvV5fZg074QPmsKVp08koveK6b+IJ2bn38SjJet65xScnZYZ4bpEbIv659qWq3tJVZqAq44kjZbjikqqqqZp3HtrJj3d2kmSJ4vJWfUh1ml0uGpHV4gUJ9jgyU+N1yQ7/NOAVSXbkT+uO6xHupY6gfTVlCILMi+Czj4ubhNQ6wGc3dP0PcXpt3EdDoInYnEWqNwhL2MZCsJ+kA5F+wvnpkOCELPn/0Lz5hpDVJxuF2ZsX2K83gNf+YZDpZt9nssmOW9WZfW/B/3USxwRB84M0sNxRySbJDy0RXQy4sv8QJARoV/+//ja10NfeQF52sCzaeF35rSMrDfRjESGYh7WeapC2wUWuknkjXcC2kVzN3yz5XPFimYbuOPqSYqDjfD5Koab1v0E5PxgdHmxICaqRkzpSrTahqKT9Sd2IUeqxj74DEqD+qf6mpzBwz0FLmZ2vx7/idfKQQz6/lr56nUQAvLpJC0gjuvJQmf4MODnY6Yxm5tq/r7d+DiA17419BVj31d7CGnFRmpbAhquG6swSXzvX5eXHzr1r+UMPtQjeuasuZi07KUaKaOBU1u+AFYKpPZ85V/tYUy668zSdWHeQjodjYS+fVGRVkOzHmC+WQeEcexC3yngz3ols5M2do1Inn1QFOGzfb0mioXQCR62cqGLJW654+fkfvZwwf9K+lNYs1jqzxl9yE41Mh0fnWIWzsjNzNeesx/xFDry2MzhgwS6WVdMyZPCT2iSjm5ClkeycZuISPSbk9s2rZ77FPbK1HSTyN6lhmyBxhRTv4TD8njxyRtEBrP6WpA9/l8rvt/ocskalIWqYI9f0V95qCk46WaiJU71YwBizK+85UFpN36yZlfeHJtS07vm/N3JnyS8pdCykHW8ETkO6kvmkeOg5jUtYprYSgWOu2rL8PDKlNPaoAIdpMgsAdrfj1sznsMaeg0ZenGOx4GbUATzJAlU91n8XsaXOs5zwceFEPBIGcW8JHEHpO15htm8TLVL7bfewYAEfUNqFPt7Fj/cqoIx2/Cdb/eD3IpZuwekomwQN4rFGgs7MPGtAJB7VEz9LilexrnL4iYK8fdkT5acI71c4b0GV83hp1TC5qNoww6A2hQUORI9AaJHPW5YfCyuErAer4TjymCDmh5fe2vyOTQWaxVAQcim/Kwb96x8hjrsF/obx840MHzgeQFIHkDyE0oRvwiVZoA/via3f+HU9EJ81pMaU7WP+djEgaigqRmQxpMy/6LUFLp29zZSnFfNSm3WA74ZsbTG6XNgEa2HjT0SB2BuQOaEJAlbYp8mBd6GDWZKDkcwyyg8V8w5y62Mhqn1VtGfu8Au0Xl7wbeZf+yOlcR5wubqLlOQ4DlmFxInT/g3qoNb4SIVi645vC87VDMW4fK8HcmXGsGLOBgh7P++y4b0JEq31Idkg22+B9J2JefmI8bmyNWcMGSeWO8J/nbAkX6yaGv3DIx2Al/KolZGhN4yFJFFOmolxOusCPKdfMqFZyoeSCYQCZ6Je5xuHqzmMlTdtQuThaVVx4W0tIJ7+Hj6WufS36n6MobAZBKdYlhlIy2hwE+DNNQyKK+AvtFTgLqi/Q3iad9sXdDU/QShpB9oNtG5lfw3vLsdUHJZBvk2O0hwQQXP2YIprzhLvLh+035rrVOgFDaOdZ0Zi8McfYFVDzm4G6+1OvRQTCaKpo+Vkq0ZQRxWmaaa1d4TX9vtDj+LHO///lw9en1wIG2gFe74kJtiJBNNBigcle0T+WYKrdUsiWzTA4zZpUu6aoF2kIWW6ejX/O0wWt43Kx6J3jA6ey5V7RpRXkbN6LAdV7+yhSgvG76mKrTdA5Yh6EupVkYe653euZ7Z+wmZEkjFNiHr18Tf2mRuySkN+MliPGqMxobEZPOS2VCTp2eWGfyGZ+6tcH149jxk3bqd2v9leV/AvvKYRgbWpMQbS0z+suKV31QDCwsJ7QWoqFC0agoDZzLbMhi4te1Jl2mLSKiOSnCgIrZTVfvp+o/Uj1SdKm8o683z7zWq7SzYetVFYDql5O1FRif6gRqbuJ6cYHUuocQfVq9dmj8DAcrRqpmL9R9sHMEk7b3m22QOj0sWaYjYOvyjcuKvJjp9LlXZ9W1ZbpjLM+3tjrI0YQGzBZOJdnm8P30xqZYGtPltxWLZxq44z9GzjRn85tFJGkDQbjAqtJuNaVxbiRsIdlY8zMXrpBiONC3H1wQkzHn2HFnjxva2dwtJD0Y3fIde5daQ5IwFD1Gvncf83dj4E3ax+vTtL2vhNpF9iB2dVD6X2DK9Muh6P2q0gxnA5NtnOYc3vmAuTh0kzZgj25v8VlaMUgFQAOPuWAKd/1bQEZjBFzesmQlPNvfhF3wVnOmHega7cBi2COq+4kUNqC9I7jGH5H7PvHlvMkcguCrckssyMkRkqe0Tg8SLc1qsU67SNbKssBX9nJM2Zl9H9cAWXB/xHRQgmWSYF0STB/6w01yboV3zMYqMlTmYS04Ydl2JzTdVLxDqrL1gv5dtUEL15tY0fkmsExi/77eWK3cBUbGMCSVGZk7Ti6Rk33NPQg0TeHS0s/wOpu3QZvnfPIb93c+zyqAj0ijksUXGjd8MuQv9e/DbMTOM4klMu5E1rLx5RZx42W3ruiWrraYCLG2Lt7tobSq3u2XlXM63K8UkPrwJb8AjaWx2eSvwcS2SqEK7Q/tQoWOts7cBd9ziH1zK2Y04hOjF0snOkUjF+xJExXToKZn7KkHvUrbLI5SsukBo9q2D5/c5Mf0I7CefQWwVA+HZ+gLIbsecxXhjNYpYVR+MyKBWFoooErBPaU7nKW7YvwJWpw/L24Q9cZiJLgugGzvC9m2oRD3jf9ki7MiiJre+lNGtScFWJ19PzVIoHhesCiU0vGzf8RqDbguEocV2acm5nWDthyRm0bvR+UwgUt4/JyjQiq9Ca2PkybUy8NKQXXTNWgXgVAcABH4vbSXf7CJ3ZCPuf50rO3y2z36WUFYLizpnHMTuG6ULxOwAqSpFOFDLkmkLzopAaXuvjhA+bmgsjw6s3eE6EqCfHmYowX9RQcVYYIaEu4zTx9Hum6bQTKs2ASOlS8jOZX0B5hs2Vcm4sZRQBsPx+nfoCTk8PSBo266PoseAUJ8hrPfFqri+/IF6HXlWcz246F6ARirEZIYmXa9Sn1rSqsn+vpb5/udL7pYhmDcPnKaClsq7CmM8UOO+KAP+nVrlp5/9Qc0WKTBZVa3jSGIV7dWTFyA+Qr78hfZakLRPeS2V3FyIX3cqheeATqZafTxvA0S6aVq6PwaKEwr6+FxdVUmKAlcbjviXTKQ7EDWNDwOq+Ulx32r+i+CTV++eFIvLC+ZvxdLmy3Ga4w1n3FnKb3LWnyti55o8QQG11wBbpFSubPWcSWl3X32GVMLfflF9E2gCWBqQyOhzxvghvTdWFO2j3jmM49/qDUqs+1RmZDySMRfcCDAJwznPIdvc2cAjDTaqnhqdGOkD1gO6vsU1/zAg0NzOBm8EiAyJbmoUjkicoKwjkv2A5vtLIzac0qCeDwD1KTJo+DczfND41cUqpmKgJ61e3zCIi5EYHvEAB/pgIsnWX8aKOGfqc90QvfeKf0l30z9+uklAiy3ge8lcrLkXkpwAr7lZjc15uoCvrKNDtntnYRukPRQAn20z4KqZIJ51CuCNUJ49LgXEw1lz5J7tsvCTHVryZne8YsGWAJQEwGUfGFgLPBr8WX+z21gUotR9zVxXtgeiwqy7BoMXXfeKvIevM0OTOZVgf8suSoC8chQW8pCt55bZRH2fBVePW1aeYZkhayKp821crhPlqTx9khmI5IknA3tRVJJj7qjxtJjb9mDlBX/+okSWoRXcX7pG+vdeZB7M2l75Nv/OWDsDSHkAafX6MN4TR+AkcSps8sRZyJK5vvVf6C5oLTiSI9exe3TJlzI/MIqX/O3E//bYwjFn+f9BOpI915StmDUoRZ6wSyJJ85xIjkk1Xak/CtwghEkqITpCpCzndGD/PwIeJfG0Y1NXYKdo8S4CYCPbUSBem537A450I9oBhEbm9+hmLTRp4B8iNxxyC4lUaodF/idP7k4vw932tcANyGIZpyPuMy0FBnYtDgX2yLeYC8VZb22WR0aszqAEf+0DP3WU4NrAa8Iw34lr6ggTmCrZf1O+4+u/YBO/hKTF4MHnofz0i3oRg4rshIy3ytF2sxKk0wz/ZXjTaMwMLLYwZ81ymBSjEhV9XjsbA4ANgYzIWBFX/NxEo4u9IV3DNPvUFGlflOh8HRZw0DZBU8oa3pi4b9pdX5IX3x4dDE2jX+LpFFdgKX3Xz4/6elxDk5tAO3WmroHL8sBT9cWpsHA6R1MOb9hHA8YpknlPaAmV+bHAffuhKZl1p5FP2LtxHhizBw7eGapzgKQy3g24VBGRLt9536UgfNFGwJ9eZLisSpYgVy8YrpQrH5iXb2D0I5mfoAFaPqNLrDf3FsXaUmSTZioI3DOwDkpTqJxgZDiukEip8VSSKlv72o26y7sYHYi8DwDTm6ZJeNTd7M0utZsv5FeV0Vpc3W7aYaO8rwjW/ObB0W9lduWsjPoAijpfbBb9StpzrKgaroeDu9HcjzRFZM76pdFSHCZl9CWhI9KrMsjIGPdECoCPBcmkrEOle0GMHzFz3VME4JtpKegfFgw1AHVj70HC+FqjmpSHrBZYiBcMVyfiz4Ou2n1ze90uUs95+xxrZB58guuvy4vedIfLAhJPrWs8BzTr9JJpRAqQdqykfJxUVj0DKtwYqnyVYPjMClJvmw9Up4VfWbC9B4vLoJghQ805kPHkPeQJRuyIMFi1QLBFwjUFvIOTVNUkPfpjAsk9NJmLQx2mYb19z1WD1r00+XqVrrBgNDgtezkoFQJeR4KyjgIcgk7arr4JuHfdeVTZp/ZCO4rAhACDieeNexsmj/CcTwmqCdT5x77C92s89kzn3C7UZc9pMJORNnBLIQcbTN2aWGIBPxkZ7RtjSa8uFn4M8h3b83Xp1C2b96x9CVkqmSpoj+EiTO83FXiKT4GrIcGsSIb20HgUf1l5WKhzNGdj4u0Dio+rSAE+lTKasfW5FxlEwrhC6GlSzLGLUR3IHUscc6hNbCkudfMTQ6alH8l8UWgPjydBEEwdTI8Wcj5hWpBcTLKMngOruHnY80TNm9D7rtaUR4wyzSGM2hKlmdR2f1IpYziEoNdOksh+DFF1ttPWIemmL+tdES1oo0Wcw03oWsSd/i589Rih5xP48Zp5lhftamjihI+AM51NiBtwqEdO3ngXt9g3lACdewAtQ8SYGXLaLYuGFY98TMeV3ZUNtcRGyfLAQ3+NA0jLub12+KYfjGcwuIAYQ4PZQpEraqHiZFH4BlOa3mVTNA2vYX8FXcpSQ8LZEEa2yL23PqU+GKJT1OfwL1t+VtzSWQYM1eqpLaXL7E560a5aCpkDgHONqJtGWP61KGSCdMxISMh+WC5oGV3APNYQEa/1X4AQ+LYkv8OOn5BWgBKec07s61581SJby1FUlEMxYv57IraKlADaaXV0wtaPm4O3KoLY4/UUx1YzDIdaS46zz5X9VQmo7/0QPwcOhwEVQ+6VHWhTg/t6qtqNSgqouSG1dr/5JYCCYhegJ/e5aH2fqeWN81NE3LheTl4V3qHdDNuiscBGpt7cEtQLn48wQDsn51LUEDLO2DreeWKzKqkfuD5WzBPB9bw6QP8MAsSIL9GJhw9vDtVOv0zmHUc+nz5IUlt0MlmdidAKfpMBHZtJpH8pWr223PvAj4YTaQD8KG5q+aJNvYkBsShmkEHGjnAcqDMUcsl26cZFcj7VTBtVetYhD2KHuiqRJBRhQRHiyB+lw11s3uRiVDX0yvhLXYBvLMBz2oWhUiv4Fb2nS0h56V9p9mugzn3mwjGGv/PZlzbdGe6ImllOXxjQXnM6s2TCM1tDDKJi1Y+GhCONMCalwf4x1L6UjSW76Nj/zfnEGXFYNe5xgywN94MfEQSeEOs5ZF+TCwfHZSkjao7OvqHsneiGssWr6u/aSuGRjI4DFBTYEtvLsi2MPMKpmOXQRgRkubYUEVpBVCqbMWIGAJj/9q6mn/TOI0nPL9DkBpDWp+p8E9XG2F+SwY1rDqLv8XKCmVTy+6/1h5KpMvowLPGkDlAAA0kmZNTly+EGGpRoD8urim9gNBO5Vr+Re4WAP3vAwHmZxKjmoS69BMfYHl4SZIWyGVKti0tbwwGdRUTwKKLqVUl9KJNiddMknlracRley08JA5VOBc7DhyW5vt1IsqgVhmx+CYfnR1L2BluNlpnW/1jIwzy4HAZAhg4p1b64lWArnhQAVh9AgxSr4Hj0RsDy7IlfzEKBIX+c5KujsUMSKmV6QcFELnUn6dKCABvXl/hSLNuWbvRA+EJNd96Al0YHx11XQnMksXFyk9crr8i1clc7MheAc4eNqhO6kbxXPdbWUktjKjAvCZb4tOrZmwzdZto5ys7XeOxnCzpZYrAOH2NhfyFKWtGt/RwUAUWbWH6/DrrQbWQYIKvqqGcw+DoLjUq6gPZjenNXd8FkAMi0bNlzoFE8bHdnBwhygM+H1BZNZu7B6spSW+Kih8Ma0pUp5rIEAVUnuzF/ZhaGMSvWJZoZHwplAxCML3xE5ezB5odY+4qCrXSey3bGX6fPWXodtVMW4v+axEskrt7BpgC422JbuGlee8ehBMAECqbeDE1hBu1mWuYpt7wOCWSdUIBEIRuGHJ9E33seRq/lnyIo8ttOztUkcZA/WYDv9lD36ZGfqY/Cleyy3na8E/mR9IsZujNgfS7hNJsNxPisQmiTKMnac8Jb/0Npx0WC1Y5mdYZnCgnJp2H35NpIdAjGW+3EtnQVQXd2rLak3FZqe7LCNvQkK6OLz3Z/VK+rK6PZYibW8wvdK9WpDwmyoGX/vCqPYJvF6HYTwPHl/MP5tq6V7HHjW4F7uwOOi+zvv2hGEfIl8e0zaMkPFrcw5WKoGj+BOPQd6PsrcKE3pNE+3dlq+dHNWVIQKp32eqE4mxK6U4L8uOt/9MTwzsVpQ5DI1qcxUl337n8jlHMSgOGZELl9iuIKSq+FNAtGtd+x8VJKM2YbxWFVknekeTIE+zo+WvJmNyWXE+sUEwMqpuYuHVxf6Qw1j18GtoHcGpSPIwC4r0HaC0236JAKOQ2x9w7aZyB7i6bEEKOY6ZVSJgyXssx8WPlb7LSqzou2vuY0PkEUPErbn+HOvNXDCRXMMzbiC0OIQTnRd24Vx1WRvK1umCh9FF/vaYo/I8paMbBTK3hhDYgppvLSwuwQSAZ8iKJNpCoYA50rIvvNPsR5Alap0FROL3XRSa3qezmZ5D606a2XKR8CsIG2JLVKtAX0sr0Ez312yBQMGyW44tLeXzNvg7BL98SYElMwW62v8RLcd6Pt6H9+974CRA9PbxDZ3QtTvTBwN3IBRExUtBtloSyVz2MztXfQY5O/MkXuvtPf/WiOB6+ZXe3HTKp9Fsox5RKgTfy2cpXKq0g/Qr++wfNCLm9DHND4eP+i2rWcdn1lh7WoTYTOgHMbNp4nvbu5ycKVEOq+Hsbuqf5wuAor0i7VVFa+sk3XOp0NS9tul28EWlAbGTp1E/hF3gq0Fs8YEqLJo5DAxfxi/TtxNjD5XiDbsTUgVMZycOo+ApziaHdi8O0JdQVnX4riugdoIybANL0FtWgXGaqmO2rETgkxuk4P0gMwswmpzAEVEtK/RUqXaGPW+OK6G6LBc4BIv2BTNOTR+JER9OAhZO1AzFX1P/gYKXwp2qI/JHkR6rBYCq6FgICLmVvG4fLiPiYTALIAxG+JAIs3o25wxt8l37JjM7tWs0HwkQ5o90otnyEFbZbVxpHhZTtIQWdTfrkoA4queCP7nFS4D4iRNioPlno8C1zncaHOaXXx3/pUSjsiFQt0eC3mS3e5JQCv8QssVJ8MFsDFWAJA0YGE075ByQ/7J49hYWXP2wl2cAou4u16jv3X0ftVXWAVJ0kQFSMOavNST2z9Vp2ztP2pFE5SpUB6ZAtuBc4utHBl3Rh0A7IOOH+bbZJyYElIikqxXRQcy8s1mydnzBtmCKT1xyEeD7RqklQeNII2Xhb8RjkTZ60OhpmU5t2cOwPCQKTyN1EJsTEawB8OqpeGzIqqNmaDnUzX78Ev5bytgr9ux/Dy/uMMUMHVpL1UFFumySJvq6P6UkNvrTdm0SNRU4iPkCnYfWVmgfkgCq6usL4xE6adBx6srGj0CHFZ69P//5/m+40EAqamvQNsUdNBZ3QlSDid8sWRLHZHlGO/HGW/2Asf6KHqcRhZXOBKwS+LEAX/cpXsBKNfyiwrzKwooea8Ac/NnqNrY2Z9wuoLJpdxmF8ae9LiyT2WZSUKgGiNtjjnPeybpmDZopqLRYt+f7gKi3syCkWaOfl48wDzrEGSH+fvGpwWxyuNr6dGe1YS9nMlgdEB1Rd+6C9/jaIC7DJQXF12EwcWQpzZ/XZY4CpjB0BCAoplYIFnvRNR09t6y1ZKonimjPZhZynhLLjchAZ0oOQSN+UHDRdk1/6noGp2srbJCIAeRoYpJr2f1TyVv0QiBt8G8JCeJOlacMEM2ozenAq1YNxtUhHSdfVSzHzWn1PBI7HExpoT1BdEJ7BD4TtV0WxDZ/aqCadHeXxNXRxBQGiYgatGlJX+s4zK2JkAZ/ILgDBT1tOH4emrYEKLYfBUWaU+Bv3lMGZqIXLNxJEd9wXIa+++Tq8Ax/DK3sa1QnBlszPdhe0hQJPLnN+LIqX1Zb7FUZfNOFr1FU8ZC16xyVoKsBTRhrvRNwhBNcy6wv0bjkOrB/EFcAi0oaXi5JpnSOySbNw6zywsUz5vKjKwGkzfkU6Fg+5oNDvcCUcU6+ktPR2sMulKwnuTc8tMnUGYbKPZJP+tgdPM5dzdAXHWb2oI3chaK3BJtE1vDt5SyKt2vnL25n0Y1DhZDqqXJHLu8OoGdveahSsZcedJu7oPgZQHdqSVFShsjrKeGLA6hnPX6JsycHwvLueEdt22DH198XYKG26tV+EoV11Dmn2NbftI1pRC6bDUzhNpdUKJNfcMac2prCpgPh655VZQyRujikMAFR2l7rpHe7Qy48v4t4jFgXahpAOFVaTr56frEQJb2wgDDG5y043kdrKvT8IfKGWF83J+uOlb79wa7YuguO66VU++yXrVd+PusmLZWQdjV48K/qzfNGpUfJ90k9al5VHinwwIH5kqw0abubTPRY5QlduFY+pQ/D64jaWG9FKyCBPbgcv3EuEVyOoHnKu5PidMCh8FmBuTqL2DbOaFN1u+yioMHmAQ2yXgqdP4XZbL3atTrclxv+8Ty8i8lu2YDEbJxOe5dlodB1PTZVimgO5t3PGXMsKGP/WlIjG/CWawMfdATwgSrw0eYMp/771Eq8yPaRw1KNGwyLZ0gQd9SaVUrbvVbPyvuDkeqx4J4GQNZiPtkS4XypvY29tNRDZQg8kPLoc9l2L46pRc5LA0OJcn/q0bSI4cQifHG3s9B7N2HmVBKdT+rYTWz02KrKs8yh0zJm+YmSBUwL65nrFidSEBmDAGVbsvcyJZAUR/cPtS/yXkQ2oSViy6bRnml78iW+HFNLWlHWMn8S2tGX13n8QPEInmSNF9gscLsn/WUm8R2gmvXzLKGbVsKBmYhgmmgOhJcfdK991c9vyEMn2nz4/DSPmNN+ZfqEI2zbT0tc1GXgSwMMa9yy/PAjZFVtLXjLQrf+W2WY/iSbycI2+nFguSdKWgvR9FkPNqKSe9mY8M0CXJogmccfIBBwu8cOV2DMh+Ve5CmgopBlcZRx46DYGZNQoIyYhuSv5BDiA/VY3UVM/K19gF9x5hrXKLQ93XrKD/ZRB/wLScEBK5/wo1bijclRuM5uXjFcFe3sRslCW/m+UYaUp3AsEjeOYiW9as5MysZ16BYZT57u6SWLV6FzyQNt0Map3/3tOz7dK6Fk1vaL5mEgLWOtzhn5jmfG5rcVHVdm6mfbSH3Fqv7N/d1EKuqxiaEP1frWm1CwxSBUkYT3s5xVT6Cj0SldQWYM4ms8ueVbRBOwRNXr2BnMcfBReOkkoupykPg8uMw62/JwprHVI1dKnJE+TTrLKSnb1cpXCx2USdh3FHvyLkdRxY3k/GcBpHuqBLIHBLEU9Fs6iAyX2Khc/rZE1XZLTOxxN2Wjq5KYtkhAQ4cR21ArPhYqzqFDQzj2QXvud+oEhH9IFq1b8RMb37KwIkB9DhaAG0Ih6TQh5SwB2cGtsYdJNecLjes+G1sAYgoEikRzJle55E+MH58N3sqnV/aRtU7u0xxJgs7celvLFMWPSuTOXEop1dhOoapVDIgDnwvRy/y6mTMqLZkeEIVGGLOVEuW8NplJEpimXbS/GPMT1MLWPlZFRZbHzidek7W0RFvx33IgEScb/wsW1+GSMhLBY2q0SjfZ8BtxIrKfzT42gPy6hLRs774Nr3Fr0amUR9zmhssHdEPzbjWwGTHBDHKyuZCSmj1S7ib5xTZwAKM11r/GtCVgmNvoJbdnmzDsc+FIza2RHyMnAlHVjfsNa9tQlmqFarZ8cYb7q4PZsV5mnE9688yHDE8bcBCiILe7qzKgTzPrfSZgCU43fUFCCkGXLvAnUM9QxGStdOzJQoHx4POgv5GAQBZl5UL/t1uyOXoH5r9eEyjskNQsYSUyCPJVFPl9vG8+1TeZMrIRBhEzdB3ChYG5YrqcFvZK2deTDtRAoh+ANSvrdg9taXuPuCqQP25uYjH0P8yPggJVqtcsWYtply/+TDAss/iY0CTAE+yd0vfs5sH1uS2i5uEePiyHeqaaF+T5Y1JqQxg9QGL+p/XvF3zKMGv5R+7ez6qSxi8zHM9IuNEgIeC8WLznlMVB2fSNubm00DDDwx5+xFeiOYz4wHYGSLg2MPoYx+kN4dXuo760ukTMYA82oDTtqzLXoMUXl1meyOZPI7eFnEuyf+SbEAqryc0THqoNO8iMMK6m3a/bv3CZkI1lXuTBdMpkGaYMQ2DQByWfD2mRUHZOvSR+qY9hTFTQRYnciXReQbk2ssisWQ8VKFeqTuICQ6Ci1B5rb2/YYZOOZh8dFc0Ea1BPavxi0FxFNTwC6eXh6npwI+B+fZTrQE+4pmhHbOioxuaFxflgOJ8MsAErAFT5JS2NqvphY6raMRVLvgzcarXRLY7Z+ciinliaYzJViD1ctwABRbkcUk3lX7Ip9ZAC3giXcSlXDyEsYRkKQhSYELt4THaYnq/oJXo5Smln50fgmcD0cgTgqGBaL93RCX4Hhk6BmdPUumv/nlC8kst2R02HILW/hAlpUoFDNxtqd5e8Q+AfLnpXHDVqD38D9UeeU4SLXpZgePLa5mvHV/0S8VyWx9j3lERCTwIrt/OmVK/Bm1iGWisDBQn+vFPzedUUbLxtLwtsMVS65kbHUSNmlEzE6Yw3TYzbuSfJ7bY3yP3ullXxcd4mEvV/2QIL+PBhqrN/3xT4hPkD5FhUZNc06CDRGhfSziFB6PUGHUNT9IgKfypFtlWi8rfcei23hyWEcPyNTI4BF//gtG00ita5tsOA5s+FFj12y7NMOkMljtCeThJIBgmJq8vtiFvM43CEkCilhnHpFXdG6ZalRSSp3moFSMLW4XnkhP33xxLW3IigvAjAhv/yapxo2IuxET+OJ6b2Yf51yevT4KyZPVXaCnf034h9riQOpT4sFJU5/UVy5mp7b9BkNwTHgyokwMOLttEMd3npzyDoyn/RRfCZxIGDMi/IGhZIUmEWeIo1reIXzXXk4UkiEHO2ipEnKeWE3QMXt9tsTW3WPzRVzDHqryXVTInXF89o8BxHsj9JPFmuYKgMnKAgcLqWPwoNTjwvV2xwETgnnw8cWvo1mjChM9y4EhbiI+c2akuwmJArbjuIup3esN786qcouLSx9r8614dqirzKvQeglfxNnX77Op4VyRwbuFVKGWcUaUdSa3IcpBlnyY5XGM9V4ZlAwupmBTXW5j14NAqcwLB0YMrofssWjSu4ZYxqUt28uzMkjz8+vklUtcYncvutndMyEfpnmTEkj4Q1yMEBYA7yGuP7DdQdAew0OjjRtYtfIa+mvUkIV6G9B+h7DnaOQp20H/hKQFTCGzgluuiZ1dHXMB2UHFF4QOIZglPM1uSYoQ9f6uNM6WUQu6Vd4rSI/kgHfCtoIQxsEPNFV6FzloXtkaPJiYAxBv8RuJfSbWpzaqE4sqo3wOLWDsnqmjJRMJiaCRq1c87ujM8WjUuq2g8CrLc6d9RUKVY5f2fiKLK77O96ar1ba6JuM5UbfS90gcifvLyaZoz6+8+dqAaBptVuoKpLFnrmU6uIvjCb3MpNXjpYLqvmjZV+YaQjlCScLAwyp1My7V7We1Q2GZu13ZJABKkCoh/Rxde90i49RrYy9z/1VwNiShPDTTqIJheGSERqWic3C0kTihX8/1g/tUyjH/OgCsgnW7oxj+AMZbHbxw7gCZhKGsMbOxZFX6O++k3M7Z7LlJu/ZUBPidWu491qVSzIjLPfFhiDWu+I6UtMyx9p7jUw9biw1NaRJf/PHoEL12/YNs3jQZ2W67Bu+ltDT3sunM7Vc5LM8Q+koAW/IGGnJbZM1LFDjoEmo6mPdE+8NLqGtnAW2Ke63gvfcs6I+8OpVOd+mL5w7X7SXvPzSPh0jEkxpAhY9ydE8W0JBIjdHwAErc003S7bnj64txLYZd2k6ABukwqBEzNIGKP2IOOUpmyy/IAMRjPupzhOa9R9N6aGV4MRGuzofCNtWyoh4jw2iXgRpoha2GqgOrhkHsfRedAAJbtJxFfveFesgZ+1h4XSDfJnLirYYdDX93hbTB9bD1Nn8o2wM44DiGTbeWSA18bXdICUcAT+fF8Y7iRsq94+wOIkomWS5xmvpKtsLWO2OKSOJzVPfAN29vQpL/KH4IG6Dp1eg3xC0qklpET0VUEh1QS6lfJySQW5evzsGkuIkwyjaZONFzRYLlazJTsjBpWfgQkk9S8n9HS8xuVvqDgIDunggzNPzMnsXCnf5ocR5Nn18WP6MwmtIkOJHPrLO8XvgHtx3bli9D+155laOgjfX6kN9a5fPemVSfLfSizgRXPCdym6mYcQ8vc2YCUOsNihes1VHp5IjIeRjULlH1tQ5IiK83/om9eM38EwRzw6tv5iLyicB9Sth+RZZoE5Llbm4pO0jWE6/A/0VMCpyqgu3ZfKNobj5nn4anTkXYr35tEV7zi/ywpqpm1lQal1DkXN9UYJAouU5fMMEeMGoW1WUmArWMpJbdxk+ziMN5f6ThoqSBlOPlavpqxSOyIo59c4pRO4klRFEKrATw4/00ro6n8DhTJmr4vqPbYOx53rfn+dEuZiUqiWzjnphXU7WuGY9S8q1AVRnSgfEJOySAg6eDeTS94BjeCHv0OaHJWJj3lQ0s7XTBtYhQCezHsCn1ZyJbXo/ggoyB1YHflRNlPvuFlunmTNJdxyhdBI+ZIldcNvpw84rQFIcf/dsh+5Mx8qTyjzr9AFP2EVpcaU4S3gsezLz9I8XgJk8uRUdY5qZjZtAr3TEhRotU+A1Wuqhxls4OZzKvRSzfVX+qD2nTWLfq0RdOuCvDKiw5A84GOa0I3zU9xWyeJhprgbCjN8QxtLN1A7iWQvrCpjpDNIJo3c2Cjk0lBDBXIYiwSpUw3pdROUFe3tsMJXbswwfqgxGz2ifyS9MHKhSfE0+riJr3OUhEagSkFmVsqPQUpRJrUfG8JNk8VTlSMXbcgfCLUA10G2VB2i663FAZRk0c/dBd9meUwpDZ80l9vohBFXPCrsp7zWEDVNB2veWCG4qqVqZhZPpeg8y6HdZ3JvRvzeXX95z0plF01+IXGaxN95SIAkVTzjUQEHx9NE2ZL5hXsZms7PkxHpyoU4zC2x3grNqy8WL2A7AKgx/s6ivDXbUhZtPou/Q4pe3dBHiLyNjjdZKB5H11Mj+AyqD3sLNs4SqQB57TzKSCE1OdqAcnL8hA81BY5qXmmYOFowXEf6c+oTEIM2N034Ke1viF5i4q65px5xApAN//lcpLJpfn+aceiCMF47t/mLC0pQ+uaNlkE3f0WrrKsDlfu42EC0+pqZnkCmiTTEjHJAX5aWilehih4XPCH00XlqS1cCcjM7KEfkMMNBu4yt62hStECO3t4SIHXQgdXHGSZgCQ9LgFdpiZTf5n5S3rCeOSjyNACnOpP960ps0bL2w10ReBzEkP5E6wmNS1bizfQmO+Y/GGZSkGlE1n1n101JotK6MVzeHKQtlivDCn55cTgNnbrjFja/1o/503wZEZMwxe+es/40Gb5uUML9sU4uJ6VoKb/hcHc4CKWqZQ4PgrABiWx7reJBJV0LrXCKT+4liuA8BL01SjJjfYXDoDUWyhxH5EWhFvdzG/sN2nrG2L7FN6NqMo30VqazpnvzqczRhu36PHm6dJKlaT4eSL/V/gxaNGZPB6WTGkuU3u6d/L79VxfPmviy9+Fs9VHO2OhWNYguO/zSdA6FWR07F3T+KHLFQiYnnVQIvwB88+4Bft2EjakOLVfQwdd9JNCeloaC50MlwapWk2XuBKvSQOLMo/jO19Muyq923+gcvE4pRDStVfQkJ0UjPWndppDzZED/arnNW5vKa54udS72B9PPBgKWGPCnyTtFVcjszHx/V95cXOsbiuBbAWnO0jYbDxp/3DCNrJ9hOkdIkjOgLdsy6E4sEdVFqK4OQQDvjR5PMynj/AHC9BMasngUlb1Idvvi1DF7qRn4itTAWM4aDUpvhDDyLqEWOohFoHaKnAUa7PZmxt7hx6gRdbTClwznABihwlHBdX2WEicBrSsfCNOxLnJcX2hitr3ZE8PEbMNxlEyF1smP/Cut9GKNnsXaa0bGPuI7fxW8g8TNUOzw099FWeuZGpWUfY1FARVApXZafACRtr50SPiTxhUGrobusEWK7i3PzmjjeGDmbQ2O0SwCqjzV7+ez6oqx5tzdEX+bvH59LL83loPql6c8/FpKWIt+KJ6Rg6tHh8zLfognALeeaW0EY7zjLJRSJPemfXCKckC+/XyldLoyDgXcOIP34e8S543dSPM9Wt/lYwR4wK9ed4dPTBlnjg7vZH5xwumtFT1q4JEMFjRVtg9BUxIgtzBmJcpZYT1OsO1HUGYObE13Etq1KXlnvCryrpqyhxeMSKz/k6vJR9o7NSOcv09lNggs5CmeiJJTioH+1L9ErnYUu/A7HyITJd4YiucWgGiGPOPtSK5XGwNMD4GI/YWr64OylAPRgASwqSuq1GX8ZW7ZASOmyNJtl07s8RERkiJ3t/2xd1tmyLGKqpo+1LL4rEw1HwQ9f1ACxtvOo8K0EAU/Xv+WhUaY5uznWU2MnO37h8ilXlHNye/QL0KrVw6/9Z90c7/up0t8NHpRuT2rvhUI9wxXxQdHxq3sDm8lH8AxQifmbqFiB6UOGE+vx9e7b5Jzzf9F09488F2yBy9VXCti8EDFQaJpXy2B7sSsoTDnDZf+d15460Z/0+W2F0fNOVDgq/+YtM5EEYaRCKfvwNLcMmE8rfMhO48G4ey65vxf9VjhHNFJaNsKEH1cn/W0XykDxstlKAaiNFqvmpCwKyzHDlH47t6Jkn5rN6TcV8sR3cvZaqyyt5NhxCV0jfMFZKf1I6ByMP3wtrsf6BvEfBuWsrV6pwVxatNYV90SN3tqWqjvW8Sr0z9gIJCM4HXhf5bb6mjKrz5g2eHQFFw6jG5ysqCwgX+LEHzIRZTy9l1/bOvn3C7f8sTeB0B9/t05D93nROsGWEJfJJpSh/XThclIBCLepjcEj13QotJnWy79kDEixRHts/8ccJPEZcyzXqR1jPRGhgn4+LjaOOxa+xDV4oN/QH8Yk3ryZ5qnY2j4iFVzDs/t4YrPbcpfY2ucWrtjW96WfIUULkQbu13sfkoOgpJQtuv4h+TzaXhKEMKb7UPBAmzSozIHp5Pjuu53Y4TFjSRid7CBEoscKy28u5mTiZIYnaLzbX4vMAdg/1HxXzANeZs0Si+JOS8vis4Es8sazEJYFBa39QSNYfTfBgydF7FK2cyvk8xbo5MbE8LcRES4BWHQ3fFa56+sxaMFNhatWz8WApFzW+lnhxrYhaJx4NUx4ERx7iOeuLDM26q0U+8MwegYW9iG3yKK+GutsOcHwMtJ/5lkrFoEL48AiyUV5tpz2kr+rhUPrAD3s3m1l7nqDGRTcDJj19bDywtKy1FpCbYYBcts/+1ojl2sQZ3IFa3eDa+3wPQo+nvTn+hQNVnAbIJyDlkOiqjGyeP81+F1/r3Li1JX4riiegh6NlhPhlX0VfUx2BStXAch11R6v5yQ5vvRM876OiG2x5PfdIPETVmZN8HxJGtG55wcU6XT7gtVXDqOpdxH+oXR5pu70/Kg2cFSkUnW9IIf8gp0qdjUMkKZjx0Igt9RPj8x0SWt1ak1WrfEPGVq9CX6tBlaCTFeUwTJkFIzNIh6XviNYavfVprAWHXy/FIi6Rg0AABGDy7IZJcf9Aak9IVj0JqkklCdFoaOEycjFJsTxw7ytG75dqnB23xKQ+CZuxISMVplLjOPUnWg0oar8qspjQ20rFah3O8lyqy8PyA7jg9Hbb8bI0WitBKnoYi5lrPPcsJTUqdNIuR7uzu7X3d/TrSQIN9vHKx8thi8xJWMig9dyki9jkkk7Z8GiZ1eUUBW7/YPJHmJ6pgB2+WGqOjaSZ/g4PYcB3CaQCHo8dNjPOBKvUTYC2Rya3VrDrGASB2FDdNpPrb6gTUEST8a2mUryX8jk/t4/HV52cxhRIolsxvLrcOwZ5vGF7TV4zrN2g8PQ/KEfuC6nm1ep9mrrwHZbM5l7l4r3Hv93fg8mhH8qnA2tc/KyzYte9ZeZDL/GjVbMC2F6fxEBOAGLKDPeCMAQQvC/VYwbGFXLf8XP4yyxhk8Xp6IXn3XvBBGNX8HKmbTRpdFerkJDgVimP/6LO9CHm/lodv5XdmEkwz/3JX9M7P0o+1TevbC0sBJMWd7jbuGYsGOXc8u5LL4BeO7HftwAO5Mh4iNJJBDI6Dwfy0pen7Z3/fj9JQMRCvSlip33CbUAkun/Cfd52nhKgqGyv5HlbtL8kHcS1ocjH/xpk3HQkh7AYPbv2fyUmoHYDI4MIu52NqONWnKZrQebezwllZ2zJclcfyeNceCIwxENHy3iqwgEwtxD3efP+fQ1wNuTgt8QYXpjBhu/K5Mr3ZIC7vWj/0YxEOTXVw1P+ReCinSuXgl9Iz+wD/2aubxrQtuqbWbK98eAnGcdSe4donJRryuWPHtAFlpLUfnBnloCfcQU0kaDZ0iPUm3flJlOtq7ZtPM7guso08vh9lceqDNF/YdEeCy8yhpASteJKKY+ToZwaX46WGf1uaUbM89WFOwWK/vlkcgOWxG3B7308ROD2bbjP8SYwVPB4bdR8J6dnNjbzAUH4TNpc47F7XZLPmQjCkS2qDG3aHHMcUNIQoa71ytcA9Re7Xbw0pZSdvr8r4P2/l9GztmdtK14Olg27ZiR313j1NyLmmgnTv71oVg4Sx7tEGgrbAEtk/8gSFWHS8dsf8f2CFhUsP2WuRH+8n3g4sf6Ve/21z7TKUwY+zxk3QS0tdkbhlmJA5jO4RdEzB7hHbrnzyuBy+bMdG4Mj+8EXyxs04lhyFxnAUt6MmaO6qA5/flKZ1rcH3QtnFuIE+nvNY/XhRzXLQjxMk6nbUiPO+9Dsc59PArlNoiIh9Reunu9XQkj3tOeoJYWoTYtKR6K6ZfE0e3dtCsoRDdrHcjJTbvrys5PgrrM6PCPrOhSqTRM4VxFbm1saU8qkWWG6/kDL1H/guWrWB9Dz6hbEtPH1jfEnbP3bLZq/TLtGqjrmj1wdo2L0aldmYDTfVzJBktdeeMbAcFLKHROGpeviLkWFqKDCy1lcKJvOK1WUhoBhgPrCjjhb2yq/XCVPK4JowCu3rH2L5WVsgbCz21CVGk8qR2ULOuNDAduSGpHKNVSjwz7TAiS4pnTKMOV8iVyuHwG0EgkVVrxz0Lh+5Bn0wR6CTuzvKUut46piW6GeiNYXrmlaPIkcF55Mgmf9+hn6YBTfeUNb3qApIvIzWhWKxE5VCNfBosmsSTTO/3aq26PMMtumuxnfYNKKZOoQali8ZmaDmx5W8JkpcILmoVm5mjh/8F/+oStj2OebZW82uRaGYAqSaDTD7tyHcPXJ+7uxp+H9IA3OfdPK3+98qX9bnmcVdxENWNE5qgt0c6XNbVpPmRn2dXCr+Wtkh4qeNDLQrkHvG5AEXu9SWfF4eofxZBx6dyrpNTiusHni0RAmXcLxaVg7ZVATrfc6Yb4G82F7gjyeZuIPmaETkViuutpRf+WjVDwHGANSfpLJim/wwjjQPVnLHLXNIPPooHoAA9GwHOg2aj0nQM4p1PgxvTr7k2t/8wlqF8ix6Cdjxic8gojrEUILrNSY2BDAAg5Ol4fgpi4/5rPXbeo428PjS1VwEZecx4Um2qbwXRPrRMSkpp3p3x7dI/TlhBG4y23CakezYYaU6MHP06b8z4G76D1wnkzhGM7z1x7v5Kxs9UzNV7KeLqBOGluzRsOufJNYDiJO81iXJ+hCjx31YHHti+1ZUlS6yfZ1tWbSiJedZT55f7qgAhhQklT09cjFxbfkuzPC/4wsszeQm2q9XMw5aLlQaNj14vKZf/+k/POC2dcXH5tXAOTRwwzIvA3oALAmo4j01r7FYk92RC0gpV5xS46YByhveROmpE8nRxrw3sXogIcplIl4XH3BDxhSOWYTywIktWaFS5Y/dqyttEjxhpE65w01hl87AVquHmvMx0x48pwyzbOYhIA99bs4XmSvadVrzEIBlgfi7l6E0Fk3bpcdW1iOZhpthwTzSWgm+rhqSvIkeJwaUL1S+QO6dP3Gk/KFdoo8WRvNNnMyoZKheltcWZmVvkXVrzZ+Qhb8drF5fvTwMf6lbyj7sQT9FKv8mQYk0U34D0RQoc6upyKUaoId9lg23bfSJVjsUSQ2dN6LqsmdO5SiLMvAOXkHBk9tIOVT6O5rXVVON+a0IfN6gmwA4t2quS40UCtiFI+Dkgz2d7H/VpV+8zTj7TWge1zp4TBq4RvgCFrypwldWQ1+J8Un0WCcaTc4py0bdG26gFQhC8jhGRqkJOzsabu5DMRn32XFqAYbFMUSZBYZgjbiTrjEveEbEfjhdTRQhx/rcDxJVHAXZ+SCWduFD1/xnifXlT1S2w87+cV5Rbs8za9+tfekUWqmrqYeJbE1Qninel8F8CrO0XvqpceBX7z9jlWzGs7OW239HDfiIkZHvNMCPJ2/xAhtrn7Rfzdjyaz0sr4PLT4fFoBx76amA3v+tUHdD46wBiLEr3MJJFyhSgwDw8QMJoCRAh0QUicz2jFazFS980CAoCyr1qdyyRrLPUOXsCgsfD3wJfmWRGRU3UI/mMUoiO+PAbSdzvFWRDCM4STtkZqPD21UM1LF12oL2Vh6i1yjGDZiZkufbvfV6N/IuC2aQ9U5DH4dfbwM0Yql+yrAcrsyFzSFrgQdpuoPBWMpNk9ObVT6bAMKWvDsmuOYmQk3DyL8drbNAH76MOOYlX9EGGPbxngKr7ZhIrT5pX5aNnubn9mMv6Ig3aGy8bEkOiUi5sHH33/6qqCpmW8/Vz76Cn1K/iTnq+pjg6YFcaN8tcqsubkj8yTb0w1xejKHjRNwunl+44GryqybdvTnSR9XxW3BbC7dLV34JFno7J0Ok4ksQjveecpo2vzM1wzQdUgSOKt7im5KM1HLomkdBLkbeI4ObCFw+6QJawf68u1NgGdjp/KzW2P3ObHSK1IdJEEQddQ1z76eMmlv8hHYpXioosm3Us78iC9giIuXivSa7zpBtZos70wuK49VmA7xfw5+EvXea4BNFlv3d3gC/Hk9Vj0BgDeCm7II0T6GHRCITC3uECOlIcVsECpVmNvuM3JC6P1YrqtZ8WW9yWyT71oHjHsWsi/EXXSPAwNy/DhAKeJALYfVVq+vNK1bvB/PCboQ7lFs+ivXLPOdx2+Wd2eKxQpWjVY2wxbBUoMCHJxuytkkJ1e1TF1CFg09oNMlbPdEDvfSCmoj+xe5B6b6o5YPYBvFXIZiWPdJO8oghoHq40GtcOONuekxE2ptZIrG0lzMT5oRgM+0E0yCODNvhxeaEzXzL23GJSzXf8CSX0PldlQ/UoMlujFEi7jpXDSfHgtm2GnRDFm5UKBxNeqw8SrUMMspAyA4oCXO456egRENJ0gP61+fWwaI8On15sIi30p1a/HHERlxWbPCIyep0Z638ETrrgp7/TcD5bGAXUknqy0nFMpbWV4ZaaTfnqmzRlm+cQGFHURKgUVQ81dvHP/aniGjAwZT+2J9B8LwRdWNgCS5gVDHUya7/8lq8uw1OOBs9dTco7BzuvTTUSFZEKMA01ZqAIKvMskr458ZoKwo5HJSshxdYhuARtztE0pQgu906vu6MfcCu+yvCJU0ojis3NAZZ7nf5zyVhc3ipXnVSOt+zvxxZPMjLAELVoPqlWP96Uo+zmsLQgWB7u4j48lbBL0WDOPDlXhQGVtKTKIhp2m9Mz4jkTRDzRR91crA13tOEK/E2gAAWj2JNMJbEnNV4axcOKxHF5nTP2kjxXvfS/9RfApnoQNXLvqaSZYrGYNPiuZzG5NcSXn+lSNbdJhLW8XR3uS5N+zM1pNDrNhSEqQW1ZwfRcHHgwvlr59HwuTIUCc5ZBiZpqGmfPe+G2zXWsYUtgSgMSIV5RQioyqtTygWYrTzOZdC+RFZjIE56s9xcaI5YbdXYU6NhiTdVH5tEDwXwTs2yYnv5usmsXVHj+vKb9HVJOM1lWJPQCyJLy+aMQqL2LRwv9URiZmC+9i1aLyjbQ+5eIKRKJwwXGdUar2Teu6lBTcMgvet/7hJnrpfK5b9S6PvcsfpD+QqoVStxe2FWMyJCWRJe7fgXhWKAm5VDK51M195RZVGiYshq9JCLBMphWo9nfy6P35JHGzyPPFVZpl1WU5lIRdb0ankhyOc//ASbjRFZhdhDzXkmTKfWp/a+9KWitQ0vO0x7cuv4Tp0m3cSQs4XDObkihlF2oSzyZqcs02MaTXkHiZxAwjuh57W1JJRwml1SI1+qLt0aS2ES9BPojU6ijT9bIYtAM8auBKTIFzinSUQDAA6C76mqD2mFtPnGelTBtRvZLHoR022pkeKuQspZou1LIJ2obr9hc4mhF5dsT73rIhA2Mu5esyvNg9feuXoytE99t6InuYy7f/ieXeknpDUQHG7UZT4mViWXSSJ78Tb5LwjFf7pTLmIQq+iKQVdnjZItn+ntNpzuVV/g7O4rmR/NYyXDP9df6V870nu1AIaQ76EmuzuOfMYr3WB9ZlkVXdOzAnsOHlVTBJq2JfSs/rMDXGAoOgyCDg1r6au4NI5reXoVaTNbm1WQqr9rE8SI5h1BfTyXgKCujvp0wwdUa858x1FcH+KzWcd8Cs5QNRirexBdnhoyMzWxQmMBBy3bzAgkUfnZ6RLKirCW/KR9ryldKmtqH+FsvoRiOZR/yupwmQxB+dHjNaSfRbRrfWLjEo+ThNC0dsbhwvklLcqzuNyfUZv+3vNQATw7aQRU1rnsByl8Mi14QlMDyN6d9wfo6eucZYlNox6mvt9q9rMIBkUoKulYMKNwgVfGpOGw3fJB0DCpsHz+Jq/Nz3GiB5PqQngJBivw7WtI7Aa83Obka8XLjO4Wea+07SnP2KteBWmkrWWMRh2+jIXh0KrW9PdWTvhbieOfuvK7t2uzTzdKStCbMlzHzsZJ8tp9g2qPEBTNahpmQUBBUwUE2QCSe3J2whzNw+X1FDm4EE9AafFxf7yRizWQta4W33Nm866QwFjWXQN+D8yqE8K1lMbZo7PyNOUHJQM9/UiIidM2rzNTvZHfrg5k2VhyH/HJPwJLORJgE15V7NhetintOWwHh3VltxDWwxvbtznNT6PQl4kgEOlsJpz8oLbZUVvWyTn3lkVUDjKGUmrgTSnZ7s3uC/QE45DJwFj4tcNvvLd6ai5irlFcvS1kJDCQtfFKbptVT7RgvayoWLqj7Cs1nDmmiJevthq22s3V+lIIgolqU1zcqEi0wG81BrXYvQvC2da4GX+Y9CC6wJ7FvwezM9bCcN/l0l8KTdZE6u8aKpgbzYzDoZfLU1kIRKoRsAn0RH3OgklJG2EBtNBwsT5C4NKzPioIGETAvmaG4D8vq3phY7RBY6r+vPVsUVXKPneLEoj29BlUkeYyY61f1CnNmJ7pLN7afCQM9N1jB/76J8LYqBmGestuePTevmf5WLsWe1BT9ydS98s0JZhsA/0ClGhAGUHPuxMmTxho57J0QQde3H+ma27ySFzU+7zbz9qE1qx+jDHEiTVYhsFeRmRUzJ4EMHuAV/gj0cuJAQyrNrN+mwilf4NR/gKF7OCrFdIfKR/PBfQWOM+LDLZtBXqMvKsI7EYPrgt70m5QeWIWAP18JyFvoDfgeCjjhRp4tZoJxxUR+LzdL8MO5sDHoHhUkuOul5vI2GArakoImGqp0qYjOJcQ/qAdeGfrN9sTx+v+/1GdiwaqOvugmkZcptm9Q/52ypSD9YDYXih+vh8KUJGh5Lhk3F9+c+2V/6B65odup6IEYU84WvD9I4qgJ3hEQH0FWLBsSKkKbueJf71bihLU7DNdAqO0jC/MR65omkOnKnRSG4uwCMRe3jqp9XB7CssFyw+x2NsbnLLZv/CJbATWngCOj1wD7a2mhBEJVC1jjAyWoCXKYMbHOzUzr+ru+7+o/th6oRL32Cg6ICCOzp/L8ysfIPyXrK4NPpSvuIuH325X1g9qAIWMwFnv7iRYv+XA6AWoltv6nk/5YMjLko/iX8S/1gSnywCTSLUSYMZ/2qY3S7gyQ4oTwBTsyI4KXl2QY7jSkjmUEG8zK8LPa45+LsyaMOWOX3sxMZlTSENhmELLH19/pNcKwUqJSBumxF5/4NtjQ0WcDLbUaD5/JLNMfWrveYS5zj/GYw3F+KHYex4AGX4MtiO6+3nBHdnky/AOMCplKw9P2tQz805ZzZ/AdEffMgpPlkwx4v80NGnVZzCq6FSyszaKJs3rgRgnvN5lYuboWQuJIQeB7SYQTV72JVF/Fvhe2o8EnlqU2BgIwU5PoJczUIDBPQmyN7O8MLwrvfGeRGEFx/3c6gzJ5102B/3GjTnZJWTC+XjGyhjVSv2XefNGJWcTI6pLrrXZBadBs54RAGzq9IJxL9wfcRm9cqOyh7OdTFwgkoh8E4EXsRBNeRjR4TPbi+Dyd6KW7zJUomSTX+UDKtZllQfLSKTJ5YwlFQ4wB//nTk9T9uOX78tOy4wrZhUJ1AWFVN2k/oAEBaDCxtkEWxgz7IvQ2jgzuRTIYclGzyVVPuw6l2GYaZsH/Dg8sXD6g+M09r2JMxjRqDdEuEj3owa6Wwj350A2PTQ0nJtrtcoGL3OPbFTHrR+WW8lQZRPFk1nfUwFN2lIlfQZZBlK4n2HmjExxETAXNnVaV/xi9VLJNGOGkyL8371WyS1+coBjR0roEl3RhZne8s/H3ZoUVonBExgHDnE0OVyDcpwmGSuKn0jy7DstjAZTURvu/BuD99Oic8hGOLt4wkUnLuMNkH4Yr0ZxL4/Kk5Wq9gb3pUiGGDz6TaJl+2q7DAus24phnJ+Z5hOi5F9DXV7iz/IHC//8lMXMSfyFOQz66jpAMxrWHiFlb4l+/m8eYS2wx8zOs9gNe1SYFFN4EGTx0x/9FM+s/RaaermC2q3+rNl8VNUe4I/keTOm8U24m6gVXrMiI/7zhP+nAXaGOmvS33a6AmeQuvaaL/smk8q/YKj6/nLIWk1Aw78j32nfY/3/7q3uUAmzmgBv8xumz6aDd+RaGAfexbgv9DdK2bzIHe7VDGpU7c2jfcKcfguGdQC4OxNN/7eICZ2bv+uFiIs+qIQFyQfrQp5pgGP68pecAV9niUfiBaWUKiITgGawAossWxAUYWTfF89JAkjR9N63aAhU5AzNFZdZLV1RmVnn24x7eLUpiLmOexIOlCBc+tWzmPC9Ig/dMFuuJS6za8T6McVnELf/1m7xMxzWVx2qh2wQXbZ/4OE2tbLm2SNKrAOtI5y858bRH46csLwVGwd3Ub+nrnE+VN/cDQ0tjb2Zj5I/FSFBOhIVvNYOfb9bv8YaKW1CZSSETBurOqEC5fFdXC0lQGvvEC2V7rKzVLoZXToTAJiuZDn8pEDjG550HC+/4S1998A92tqtNcEULgY43iO6LOBhweLZGzukV3TMT2Nq7twccMS6CyyQ/tDQRGVdj1QI1jHp4j5y2kn0sBfGtUhlqF+HWhsQjXVG7w7/HkuRMAxtz+r1A0pQ6GeTOaPHCObSFnMQyL8hsTpsc/yvsj5JLQDVZvNiD/vaiS90GYDGOPyAX6zwTRmeCteH9EJdupjiCaA16NfKWy9abEwfxXndd2lltdS8iUVHg+byYEiV3c6Keov2JioZxPM15WTp/tYgr+VouQ9Fyd9qARfvPf13/cFfGTSjOnP62eP1WW8P0c81vfTwFOOghn4UwOcQirLMDkJeJJa6Ov1EJucTJTY97PdUCRdg+jeglPv8nAmTXBfS4aQtERbWoReDXXMX72ObhiMxBX/r7nj3bVs6qbXsFKIrnTBzwPHytv14JYr/Eyw42MklKe7B5NxCrgzBUOzD5QJ6l09y4DK7pkJl0adGDfAAjNQMIeCWVU7VF1N3vmBMtze2KHiNnCrfpfL8osz4a5ynk4HYr3SVBhSlJQN4OUB5tsPiw6lXiqQHJWXuRsKBZlEzu+OVZzlYWjTr12bVjPkTQnki17vpLaX0KW7HB2KvU/luq7ruB45dY2usyPVyP5rW10b8RAok9Zn4x4S4JgmqSeyZXNTslAhXbPOe+9j1+0J4iw85Jt3+PWpK1S3h5Y4Hxuj6xbVDBY8+WlJi5D0pF0yd/EzHnqKzy0GcV2a0QtzaOurCfLJI4Vx3v5EvP8FScz4+kowJ0l8te2TO15MYlTgmkvJkrxy/460CwOfmyr9vy4HkwL1DEVzpRlcdU+3koAthd0FARQ9FJ+sgB6r4HkNj6wmKPoyT7q4+vduHTVVenfYhglu0sg+zyZ7w8iWt2Cf0M7cFwJus5ERNTiZR+d2vh5oxSj3zOTAJ+UvkjkeeEkp1VE9YGDpj+LBcIpyH7usGp62OFVbKclmsw1HNHGG2ROG0vjQIGW6KYTquRHpoM5i0v+tuC9ErLXBXW8LaAuk49wrlPrunkMnlpTgtu+MpEBLg+HjI+gvgdaRXXFaseX+CK0NiG8xcFIx1X6uIpycfwxRaGNMIOP+71aUgsCgOcKaevHHOEYphK1OvAx7yOjDupsRIG1S/aX6AXRYFdh66Hgy44KitVSLoaOiYdV2Fz0nrRwsI64J06jeAgHmB3jYQOEdPDrKPkGIjR1EpsR9uR+uKZD7lRqppEYTc0p6PWegvNYW4c65yn5DCkZFZ7kSYPwyNpoBlk5obsXdzYMtAUCaYr20LeA0oa6IaHIkEXQENPGVxq0MiJnJ5Eic6I53H10QozkCe4hSddCqVGp7sJ60zCVmUAvUE5H8c+H7atboRLxco0lAoF4waz6X/ZyF5krYlnwYV67RFXNzPDZDiKEAzjsiH3X9OgoipjzRjZq7BmQ+8UDdyYYgK2/hqnE4AHu1BCE5GoCMpVZO6rzNsX0c3vBpWoVVw/H+d1ExpSbd5N03AxAB+9Ny7pOHyMy6PPgMURIspcZFTLT+xOuKnm8ddyaw6V+htk2OdKnpO4QX2/3al/2DLr6cq4TUgawEjwwNM9k7+1DLNiRxXRHonVRiQUed34YotFY2W7ZRG1b7fDXXh+Rn3xtGH1rslLXFD6cCnp+b5tqhfAUkl+Vg7ePfFWdsInFDbaB5vw804aZf9kvsVweTlr5ay3rGukDOhnZe/0sMFmuvX/L/Udr6ut0y2r+FLDojlYJhB8gm3zwA2FeoufYuWNjiffrqvUZx5l2+6zq3IdWYLJyIg6Ni+kmLUWkiyFyIgKHhmALNnzsA4uc6zTWM77hYcQAOV7MoXQ8/rg3n4LDSeXyg/vpjVl/RvlN5WBlLRXkzV4X0W6/9I+QMgbXLe0AxleFTi3fxs0WxjSRZnG0bnUPyVFxFQD+2qw/PHrXC4CK5hyy9neNQzTAfTOMdpuNhlmamnsdF8NdQ3n6lW5vHqT1Wea8Dnmw+0KUVwZy/BpIdF6X5V3Xkb87PDpjSDUcMKQZfnES4gBjDmHgfni5N18DHvPg7/VOjAWmDqB0vZ2T3JQgWI3msUkq7Ea7NTDWEIx69Xw8jXkeuVLvzW58qCqHTn4EXJzbNpUMowkm94DE5rHQMn66gew6Td1Tg3Q6TROA+AqitG0gX8PgadTLFPNhg2IrHTBbXvemCOqFGxiVzh2gJtrAEy5CkcP59yJkEbTMmhpNoN0BAr7VQbNIKZiiLpm4SD49UXF8jhqbSHLbRqJ+bwd5KN9LCuxZ5TYqv/DAOTt315x34ojz2QAkE1Ndhja5atlNnBR8LifuVTpU6F3frLgrEXYG7MSx03lO/5BuHHJOTzLC2IQ8VzZMLcals7EDBNXmdPYtn1RqPRJ4fS2R4Axm623pVZoGIErtQs64TiFNj6zU4I0i+dr8cI5C0FWlfOK0qcUTGclA2Fmsb1prH2kMvgOZLjZ3+s2UnMNfuu84v8LL1JGOnfqJlsXdZrxJWtyhAlykaz83H7pJJGbQaLSpf3nH1fF7yF6j6Zgz8OxqXA/o0kcnQCos/onvP+Ba7K9kV86bcavreM9sbRPl8NpC/Gzrg9A5aNEm+RBEuAdXwdseF1DwhgCmZugy1dfeQ5IML50nTxQnWur6jMtxxKF3M7wQWHs3X9yXQiW88FZBz6kMA0fxs4Qt2JUaePuESHs1z7TitfnQdG1AgdTGs5ZK79z1cWwQ8HtpGrocK3In5zdHYULIO7BgECyjj6afjAdlF0UE6NmDmotrrT59DwXXAzCV9rna+REGKBPueNUVeHag+Y6Mxvfj/Fb+5bxUUhmGwrBK/H5CV3+sNcJwQbfNSDV+oRbVXRpt53i1gnMBeB5je44jcRgjVY5NN85h5QAHFQSpYprb/xBRaO3NnrKLWYYUM/E4FKI1oEA1X8bfG3EYraX5FNSGka9c+obWqIdvO44uyGLo6RvsP2r9IHTvQeKeAfjLswGBk5uwQnbST82Xd8sar5RV6FIq/jPO79f0yqZm/L0aWsAo2izZrCcA2bE8Ycq5OdszjPzDQhsJJEaIvTH5gCBcm+KnjWWX0S6nBa38RNyA+ojnxOKqkheJA8gpwbcEC+2lMVJl/PQ8+TZ7GQ1vPW7etKM77DzcvHKFMubLePfpBOLoE6PlISuetFiHG3LV/Sic0r9MzCf31fNgAFQiuN+V/ChaD41FwxyaXZ9SrQJwudOAxkJGGJBS+2HCPs0uoG4mv/LWWsd85XONcKZWw6J21IrVASCCA5H25DwAGQoi/hEpfPyG2V47uHqHDCHoAN1YU51BQHSreER008j49NhTmVZ+cxbZJp2VP6V72An7VJfAKREG5i1LqGGSNVJPMvqqyjep37vv6RBQfLmr957hRo7I0gMQ8P7AAZdoutf/MlWSLHQziQ0m0JG/I3yrsI1rhVuqB2FnPk1NbgxpB+IPQAEAPwUZdCB7nsp1njLDGgaNsBMIGHb4yr1Jzu0MedSgn+UcasOIfYIf4+q0HGGZohJpBUd7Xjki418bUprSg82dQg2kQWyvBXZMfYq3M4xei3H3N4PjsKEkoq8UM/xbO8mtcNAyQx2HZ3Vwt1WXUBdSLzGNjCyKayoJc4xaFVexrChx7UHuUE+aQwzEhUykz3ggkOPN5XpgBnSesSDfdQlX+HlIJQ8Jm+Ij1bM9O9C3ipM1e7ukUSy+lMg7aqjFJAuSSUT/1vPhLKrJeWZuMM4bbpVHQfGOnr78hr1rj1nP3eBEyzcMTTjAGZDFB4pJzIbTHKiTqi0za+py+PMvkP0aeuWVisqnfxDN9dovO7TmQ+pg++z9J73Zd6m2ipdFfyeCn4VtXH6GFdSh/XXSK6AFs4gGhu57dY3y7uP6zY10I7a3EnKL10hRwWOvp2dcU+/odu4NBZ4WRto93XMI3FDjf5lNEacirqD0ZgtxwbArYjhIC5+V+nAGA02uwcDsh1YZ4pt97GGVulC4GJwK489Ddp+B34N4/Ch3rpDyRwNo4u+dHpbYkK37ixVtgtEs7Pkq+SCV2uBgNTdlPT5zpUXfc+Gc3rY2LVnYhQ9MSaGyYZeEe/GThWpK7sCLelP0Mn0zT/3XAT1iawBqHmk+FPQL9W9+i+mBPA5Ap9zCzJhezfjFse6SF5uYywYmLZ5kG3XJgC6XFITZStz8TxQiIMVYpnaMneiNIxKR9ODnfPVfO0imT1Nn3hAb2o4dNaDgw4/S13MZA62Ge0XxCUrdxpP+YVmtzDbS8geKuTGKORxH19pt+JwQHUsMB4b4Ei+HO9nw14ogsry5xJQPyZmYYKlPuf+tLB8MsBSE2M0q7N1+yjnjo6Y5ZdgY53NSvLmrx75wt5xy0aXYo5JvBsVMOB6vh/tM2y2vHwgLvZ+cjxbxXBMgcWsgxfBxcn/P8M9xK0gZyg3OSfa0QlzdOqym5pYEs5TBAZDOSov7pmtKOM2lbnE6ifzTMEi49juRhQRJbTL+R5dck+SArzFMaJQ6PWXieqF6QTniNVSJU6K8AoRbLu1Gu4Bz0QsHdaVEeuIDVCkvq0KUbRMB53gYVNcVpbVd3NUUZsswbkhaj/wbdjyI3EADfYpHBvGxXAzVoUXiw/EHv1kw28jFVT8OTc/bJsMkp/njouPq2c9+Uqz/aUyjS8pYTf4lBNBbnRe9Bk2yRnaoZVhGNBm8HdfriwRYDR/MYbXpxkvza8B3gGsUXQNaZzjTlCMN5XtZ4GQmsiJpnYN24n78y9durUSbQqExM0Icq06oo/n0qCo+cp+Su80Y4fSl307aXG9vnklDA1oiw9F9bx5vXmnauij4wonC6PnaN1wLMhtEIfz5XwUbPqW1bBJiDVDZclpdKMYjk/ukhEApZApPtUTIppTQejN2Ab4oqi0+ICrtYw1voGWKAumYB2B81LSUHJLB7M2ZBmVxtnjXfBC9McFaSiUjYGAoyBlEqb1DV0x6m83MpLuJ9xAlTSx26CQ0QA3W95lbmsWzrB4tMfxS10MrfaRDkOM/EwnhQGsIEv/IHiPzpNokcswmWRf9N5uwfFF2cRZ3wypJR1EyWbesm0EjFJcWa1W0MYyq785QMBMTJIh+h5kUDXlo5FXHghQHy3Cj+Cwup9iNJtRIkKCiJolL6OPPW/SEWlUrf4szqGyFeMTLz5DsUpGSOuOzHBkOpwX83J/Qb2UrqgD3jrkZlKO9FiSFPOFVuTwDySR+2hvXvaaUwoiFxpfI0hoq+qqnhK3UMgVnxODShFa1UjNqEMsGh8GRzpiPibFm8o84PRhjcPP3VZ97m7cba6BKGEO2YN+B0xo3wpXxRZjOL7zdSlh7nepafUPF1jhBM1L19obL6VnqT71Z9VTutKAlAcRanXG3vhj2KJ2UVnClpqIDRJxv5eiG1mxg5GvLAKioUi5KZCPG8KlQVTswkX0v3x6sypT2seydNDWrpEZXkgWkYFIenlgZlZ+VJLRgwMoOzpPIohLO3/VYxElJu5qLZLxikP8eB0pgt3hgeNs9IVnj3AJIW3lnU1t/um9ocszYp1+3dkBjqd7h5adeCqPVZpYHy8H1W6jMCpTm0SU5zIfapLgXyS9q62HoryjQbAyvaJbuq6EVUqp1hM73nOt8AQbtkyMDEzkD7DrHUguZcX6m6sF8PBzndeHpOb510CJaXrXec3Fvk5gfFHL969MGsBKIK8r8t7apdQvN5cUzGeR6QF1JwS+ofJbZ2LXoAZf7UZC45A18DsgEkUW96ld8IEErJW3emF1ynBQoe5GYx9f+eoxWVgZBV45GyalTBex8m5FhL7QoBZgSrwfJOPbbvmIvrRyIs6t3vaU6jBsE4nxFmMCTCSS/eRUwhza23tqbD9Llh6X/cgW9w1AgYHgnTqoKywI8Gz2xWt9z5ljZKNMq8lCh2mTHsv0LbzR7Rskw3Yc1PUjwd4CWuVJynQtcHGZF2HBa0r5rjfT9NKLN/EaaqXI31bPoeL9pW6BW7zXhBzu2lne4ZjI38J6A7rH3rEIj7ZBPjdf5gDlg3c00Eh6VDD29iYbUVjWFoIMt+4wyl285Gl1FC2QQkIwzc4+XSuBWymlKTpoNPc6sg8l1vv1Yts/fsA/IqoHpznUcA/nlXR/Ju2XkWBs26cSHZlh4c0bfTa4u1dUHfJIB8TmFmAVDh8MIgNg2r0Eji/cR237YztE2BivEmn8XYuPKkaBzjVPWSHoPHvs2ILWHykublg4r8g4k3TvflfuhTPa3L3Acqk2UOiAoNy7LjvK6kTXaMq2buK2pvcPebWBbBtxEKdcHLkkKaBbLGDFBMxXf2xlxmMw1B4xvK+IUS9TedtApWHa1nofwO77Agz14GQsONoUuBq089YNt5hNzYgPOKWIEPIWzpL7C2a9qtK/3n/gWUKOw1CTjTdccnfq/CzChNtHbJCYR9nPttfAbBRG6z6fhBNcuV3j/QuG9Ebr7y+Nu8ih6JDTvmQXSG8Ofm2kZzoKLRoiw8Ijn7NSxvhSreJ5GZwSFcVvxy7kRKuZRmkwZDngTFcBpW07hSOamYvzTWDGL188bnzkWQwG00ZluinwVouiY97K9UCC1cyQHhBEbw4sVJeu1vdJg1Q2ex7B8ZPfcEvq8VdVxztuM6SLXl0F1t9RmzJZl7ImVm3aTOEfhBFDturSmdC2i+qfs1jKL+64uIP/g+F+OOlvT3uXusRhSIYnProHK2KUdJzjz7ZeRwj0+DF5BEdaWXrfG4cRwXhcRYogKZxcgNstC+mdek38KWdKZz9GmTgjke052hTGiNk5G5DY2hf66NdXzoEDYNeb+gmTvb7h9D0i5fP0p4EUzwHSI/5EzBG5yFj1bgZ4IufVlq9mS5h0+0lOe1OkRhohqXWb9hDiIZ/LC6F+m5IUecOV+U0rDQ/9QuaaAZzX4OD64LXQDaMPiGmqH8FgYIbx5jfrJyZe4LCss7XsPiBam1pdukyZ2jwKI6DfXSlFJUqZLjgqMv2pFSmxlb8TFl+Ju94JZv+RFfpq2OXarj8U7a7cXXWF7LKjH76Bhu6hFTXPa5lpUjqgSUkqf2ByKcNOk5LBkyQmUUbmJ5DaJERh9u86FnS3wMAp0GKM64tzDCZ0wBpEy5fp4DZ1xI1adnRajQvTuUAQypS6+4NGw5hAljJ8nBkFtGLAXS2JQAdnZ5qJ8VYQbVAcwxdqOga+LnTtKvKooWirNt+Hk6Qx0QOSBDYzFrdxJ54sTuO93jXl74L1VGgDQ20IN03pbDVAG+n90eWxHiAGI9i8wS7NSNhM2VbZwRVoEGqCxUWoJzHousdWg6J9yIotO92XELR5Cqb7W2GOQ9D9H6+DQGu3N9zB/AF6x7Wu9n5E7zOs1tlZ9BHt+HcsfTVBr0Efp+/y129s2dWqfef3RviETgwLgKMCKkfJUU90PUp+JEu6/WyfQXg//L8qfTkPd4atzv67/qGj66s8oAd/fW7CpxeMjMyz7T+Cyc3f+Yr06LIszPDUMrGlzgHMt/LHaB9cNbncYzKEYydeb5wIKCI5rE5/AYKZrlNb3ooyY/Y8w9KUQplXTf0wpd90bKnJs6jYoNLfq8B9pQ+vSiLvglwkpM/dECnRwIMhsxz3CaEl/mGn2xe4KxicP1zUYBprBLcE5Xq1qJqSeIilG4RnVZvIXrcYXDmXo1d8ecDG7AT9/0kQDFw9nL+ZKA9rNtGAOEQmsIIz7YhkJy5POCZuz0Bglstc0wPDBOy/rkAICA5PciBpxbrj1XgCQe3EbrlySSLXx7UNIeOIM6SKG64lSZwnc0bNKtyKi3WuDttVBoCWIoo/xEyYR0VcAFZ4TfLRu4/vlfBubbtm5ijm/inb/yd6N8Yf6XH+0jARhKeMwfgF1MReCEt29r4SHCjtIEeRqsn0ddeNkabZQijtTvvrjvOqE9h9odqOb67pE7NoL2vXrl7irBT3ONpyJc7N86ulSZ94vuOSFIRXphCOMILTQEEEKYewHIXeOyXgnkVbjn02CGtQl3M0gdYxi5ICYyvGV5MroVzDnAWoYsIn7HZgXSgSN14fB7H9ZjbavTaYOaXwD4f9ovAWKfUZ5XcGGvLdLTOk2OYIoo2qh/oOzNoTlvctcKD/dUmiM2Eg98tsZzi8apRys1u3+2UUg6NyD+rqi0UM6AlC+S2eNtoKoen5IZZViv5Pw/RJy1Dx48EG3WGdBPNWxzS5U+cEflrgeLmPX2g0ZXmEhu8kbc1V0P23ZDI0nOpHw2mKGEAQ0I7O01R19qQzGctJx2L/AzuEPgPZ/U8xKeN5t2DVsRlThJYCh87DQDqlxFvQe6WTuDEMZrxWS226aK6nfMUSeh7YQrEIpbyFnmaD+kwQDWuaMkmwgG4Qxp6pr+4Gi+Hzw8ouF6wG201YuzqD1JzUGdppD7dC8OEkYq04JpNmwy3ZcCpkR+6pLzApE4vW4U/9XkbNE/9PAJpcmVToaxglPk3Ll10Alib6Y1FAGEpE+WshFwJONhAIf0oH5HXbcPQ3S6KYD4f4za1mQvjJo93e+jsB21SJXhgafx/K8xQExl4YTp/Rk9I0me+8qhRhM3aKeLstjZ6T5UKhBtyKvCs9w6m9rydjpXe80ymqMtXfEUeFpmNHC/Yy4frBtDhDDj4tM+5/u4a+d2nLL2TnHe5dvz0ZP3lp6vIdRU5p5dxbZ08CjvOM1T7qart1dyfXfQbsK0CGIunBVmNE3qkOCAUgZ/82PyZ00PU+lPj01pQ0VPaJV4T/pexS+prYwU2nyM50CMYOpzrAG3LZBOywOK1bBrsKkOfRCxBFP4harC57W2/VcPlnHdmtvlUzI9qPOf0AM57FpeVrN+08udNKes5cKEKz9CQB9CUzeJnePghJzKveGlO6v53RDee5VK7zoeYZHpLKq312VYepHpmF+tMLGjEGTQhnxvIDC3kw8fHFT2/mXoXqBMkM887rCQm9Rn0TU6qDfyq53kIl0OmJ8TWk7jECiaAyUmqZqj1yN6JCM7nsXBe7ABp00wSbh8GVQrywe3Q+2/C8QDencOxZ9uDHdQkqmjQZFqugVfaPLLNOwxczDTaLa4p0Y97fifbUyy0UMONU/WI+9DbvoDeshscRf7LDzv1PUmbVd2cG5NtghaOxq14ZSJRNIS+D3bBzJNL9ARbtLIfGzwUS5NdroZtlvmJPwQeonOSU+HtenLqAlvuyFIs4Mf2g+EpGCnf7/Od/D8Yemy6/JdfDEFYezOAiZhhSmM5KrlNeBvwXQ2vpPzwSsYWdFlWxVEY3mzno2qmTPW50byR1JBoyy2ZTfMxsW+dbZK6VFAtMaSYbhaeshSb2G8Y/6NVU1WRK3DtxZDbX9YREhfvZBYuadPSG7swzA+Mun7ZMETJrF8OCLYp0u8ILa3MagYE4Su+LkhLVIyEFaKn7WaHbLO45nAg73wfco2jDvuC82W0gAsXsk9ZtJCE4Z5tmHpktqTe68uTJ1flsdNJ/J2cgVxhWKJehytw4J0TPwTYtNMJOn4t2f2BKR0OUhSzWIUuqJogkAfMsF4pZWMvbfc9wHZFT0RqtnQzFPhGB+xPcw0/XlB6AZQvHD8M8h8bm/wgZ8qXUC8RWhhTV5f6mevbvgJ1cz/xQzDOOnZPzle7qF/HQGebGuicGb1gyE0ks6YWIlJRz1JF2BkdBO22yd5blgTd3Q3y2v1F7Fu/jA1vxuzdKobOVwR6MdIHFLdthWBnLq9RrRmS4Hm3IP8XewMQz6ZlutEFzwJedEfySwBQaFpjFkiEX8lh1fWriFbHuQCV9FofHO+4ff1OuD7nSCPlNsceD4+ClS/ysKVvZt9OYPPCxP+0G7zcXrlsN7YFd7SlKANRd/M0zd1TUmFe9bpnF80pGHoBuA5IdCJDk8uD8r7W9tXlYdQFfuxo2kxs2Uyg8E+F5Op1fw/QZ2DoHucKnMm8Rje6RLZOqs0SHgIDfUqj3jS9WaiwezkteX+wBj3OU+qpugbUFBo2d26hgqUcSW/WiosEKVnf+Ju9jCXQvRw9EqKU4sSAwh3AEA2Q2Jrv6ZZhgx8I6GyS2EZinpAHiNQrlewjmoBprFh9bWPlEhzL2XbgmDa7A5iwCsw477CWI/xRW+m4B93Rkdn3TSyOQU/MpQfJZDrQn2l5GLopgb8vJ0apD1TnYo8cjCHssy0xvCmgGlGCgG03f5jGyy1CDuwWLBGcjEO/8a8+fKzf7ePmCyKChP9LppXf18AlX4dgplDj04sFHEiijJTRidomM+TodYDew+ZJQxo9kYvmUqcOAP4b6A5KJZ+MOUbMxc0E/VoLxlOBFFDTLgZqP8aaVL7dIdOQkjM/5+zM8cs7e68ngJNMydpO+e4YKJ0ra9o01e5u6v7gQH/070UWhkPMNnfjBkPFGu4Wg9B7AkmAYe6MZ7BTQ5GFS4ZCrmLSxkw3fxKwmsH+wMdDjgAUUv2taZ6H4dxemnX8OM3LRWbHqGlB2kTj2ISeJlzUzM5BrHhHSsozlKSXGJ6Ao+KXUfCOd8Li2Om+ruRTMYdsiEhGLnL66R7gsDTFZWeHhkr2hLqNKJHz6q92Gb2euQDe06j0Xgc1GyGvpcqmJKP+zF2BBQkZ3w14fucLTM3o6bpPfZqqOwPGOMe5J1C4c6tFwJ+iitjBfE6hSyDzFJKpQi2AKe/JvUe4NKG3vyilr2OvuPppNY9bZ3LaSoaDlR03iRlLgHa5qgM1ew2uxKVkGir8Z5enoiFp+VASynBjIdSBijjD+DZT4CtCYGbnSey+0ivq2tvEaFZKE+rtM3RPSShLQEBJHwgql2aw/cSMe+YG9WJrMmAUQ/gCHkvmkXarbv+A/rKxwfofuAsbXLtR9C2ewntkKflcB2xTDNNc1GO0Sitsi8RQWClwsTtDt4tWVgr3MMG2eQXm0Ej6xHRLmC2davFwwkrRWB5D1QKKhKnPicIGwTTbDAoM814ckdlSw1U2qqIVo9/pEVpuFqsWIyNCKrdA0dmjDP4Vv5tBJb62Em5S7r3RI4CbECqCIDok9h/K/xmx30JMr2qL4lhUjb/HSQZFKzztsNAl2SZm4Tc9ZfUmWyCNLlPX1rRGU8cmCPi5WqjviQc0ifhIaAl9P3HCBEJ9pt7N1MPqr8j1XoOjsHPHr6YML9vmrYrsyRfv3UCBpHg+30j5Om8uSAkzjKPFFW34jEC97rgQeIbRV05/eEN+EHP6GBJvSW+Z7q8c2/L10twPZVVNY7mtqcpR6wdjr7XCJXDy+12Puoo2138UT3+PnHkVFN5VKAXrcwEGEDkurf8vCgT8nWvKeltQC///eepV5KOWcq0s8OGSgu1P9XXfroaPNHtDq0dQ31oMybmFEs7TkGKwRsunpU8R3znTX6xaNZI7A3pWPIrmz5h3SwI/HQaKFwz/tSdJwPs5T26HYU/axORnrXPgkN73iqisGy8js3yECnTbVZrJijrJBXAHAgqOZ/YZP51ou6Lp0ocMvTxRrmPew9fzG7c+rWvUTQDSVsywhvHYKcesicZ6z1hZNhzDqnxMoYEJ/Bf9v6KOXr1ScsE0uDD3IiKxWEQpYh7PgT/DqzHirp12XccGOvpuFFDHxgDk6+euwYiKbbxHwdNtcwjhC+xSyDDwH7KMkZbY/080hMiMYa9GDn3xcIdBcGeeXKabliUjwvnktaIhHGoKfg9GfTrfMzsjFrgMw8bk4CxW62u9JMgYtZTdbQ++a6s5W+gE1ZcEnbUSswM/5dY1DVueSg44GoxIbuZcxcSX2zTQKeS4TxHd05602DQlhMk6Rop3b4M6hSjKard84hpPj88r6+Ff/9wKp7YOzhKSg8ycFvsiJTmZjKsa11tKoylGTwvWet200sA9nElzexzXx3zknnlNm9KEnO1inni0gviDsAQ41IVchqC3cD2b/81UdTz951AAWpqrEdcbhWd+k8PpEc2G0t6vvSotjI01jrqGGhJXTS1qSAVHnfiIlB08AKylGiSoB5qxwCzckADWqmHaSq764281el3GvY0KDp9cjCg1Sz7sIlX+E98XfLZvAPTp617Xi1Z9HOz9wQPWRSnMfQEkwnmi0+tGoYmSmEWtR8/A0dq3wBRV1lOkSsL9BGoAFUG0IahYsB4NiECrL+Mz7WSxXiDjhgkWa8XaNmuL7y+FlsaaV9DsRQO3wzGYXukOFKFdFo0Ov+44iDFJCdF+9iBjoCl8zOXyTePt2ttaOm0rLOWZFXEZglLgYPDG7hQalpsL4VYI5cPl8tC4L5BM7aUmSnq6djwsiNknjKUnClektRVJdUHMnEMofAlG8a32ZdS7Z4povaDSGbM+6Ez1fpTeA76WVlqHEi85Cnz0NSeSz1KX7Unr+Sdo1uoZCr316vXwpBnsEOmgLwR0OXg7ciGpBxr02Odod/wUCSJUQA+W8qnfYYaNPozwIr0BDbEGh0QlT023eNw1bg/KIY2cKdZNF/bITbQOuvddD7fwU39uFuEUd6oT6w9eIySYFmnXvux2E/I7tTADTJJieYS8BFMuE9Rrn2Pe8yBsPaPxDUNaurVOBYD1VRQ/qEdkhPrMeAPEKSiwzFKqML+eVehTuFeZedo0Vvyic1INtFgET+5B3WrgiQ2GHUWLx+ITXZnl/hlZsC+HOKxek2GX3Nln0Wg33DWHDcdmMnoIFzLbo5NFCBDpPfsWEvUstNAuFrTDba4/wbQHqyayB8UHh047eUBM5v3ULLc+XR91DWxBShwdx1Z8YWQNF6WDsZD2CvoCIHuBL5lolDxfif0CYdd4G0z2J/S04dtt2FrgFjOoKPdBJ42Y871F5C9DPool0Z1a5FszZOycttpT2rBt9O7KeSr2KI4HSGqMt0LXMXpiGgWQi6BDkXq+jNHowgz8BmBk1NdBZC4/a57fM3539qIXi1coOVbF2Mu2ajlzcRM/nN/IA7jzG9ZNkXcFzDcLx0E8/OI7gF/NnjmmT6w17v39s1cVHYpTrVzPbaMfP4VKYlvgcwVW6AoUPXy1M5WmbhR5PkWT5cBcK9hgw80CPLSdah9qwr9XlScKFbrpHCM8lW5o9GGpxc6aVX3kyxTxwhPNVZB5zbVAvPNuFTqKuPTZxAtdv4SBtkg9KamtCFc3xrknV7klMWdgp81kxR6oyjjRvM3txDT8/k1qYa+JzXJtK9bPB0s4FwntIgi8YP9xfdzpaSwKvRLShPIB52nF00nFW7t1pFtVvyRh6m0maZ73j7n9CIFZh2wiCJ5v+Y05sV6+9l3j3TL+7oxC2J8RXlDahdsrdxP7xaaCBQc0WY3Q3gmbxh/S8FSAjjLLtAUgaBEvT+KopV93ROJa3u78tPXRYzQZ9ucSOBUouTcFR7qc8BltUAgzXiyBdBbcz94Lr0gYtmHcsFfgxR7I5gYzyk/vlFvjoIPd4gG4maiFefEZNQiSncFQH87gIjRIU6HxN5EnF/eAj7+2oF96WHp84xZ497Kj/zKlbpQi55LzfHL8ad0hHyUMUoQdhpuCMW80xIfG+GCltuRkVL18ifWaivu9LRlRPuhZQyz5JlrTmP259hJbm/WfzAPkhxINXcNXVAaA9Ntasg2YRpuhopfDzNXA9ZVeTunHttWkwnZ1hy4SU7HqKRBSL5Xbp4jQDxzfT0kSqIbWOUdH+Ut4PuXNwkvWw21YXhH0+NNQYcHZlZvxWwftcZwvse/O2urLNy1t2iRUs1Dqi3tEhh6GaIKsPUozRFgzolOyrAITt+enY0xdMIqeR51AvdOjJJ/lk/S6RObxApEmlKqYhdlFkolq9n8OxLKpK0jUd0ZHdYJhGL+HBQqFMip7HW7m6KfZm9Pn0S/cppE7eYPDPzgqJMsS/HTW3eC2XRolyNqsP2gT+wd3vbZjLGIdBLMGPeo6YC7maZgZ9FctqEAvk2WKR76HKUU7Blgurajdoz2GgN2px5TbYOLS5HuBSRtf+cIvLiCJCo4zE8PLD2weM/WXnuGdqod7TBp8WgKNa5w6xmJvVNlFbZ0dg6qwTTEti8oyV7W+qrgYlh0eBbHhsZ06awdYqhxBGWceg8Dd3ZBvokmMql0ZA9TabkiKaVIXhrDnmpJLz5v9U93ezAgKwtk70K+jf8DSIXJtfuOq9V4hAATk9/P8clc8xQGIK1ROt5mKJTYuhZYp/ntfhEWBP3dCRjyUB56smvI2sGC5fDpyhjto0lFirYn0tQnK/LmcIFuGwGxE+duVKx/5S7o9ssEnROjQRb0lEsFA/P3YgBo0gZtouqGR9b6LJ3C8zRzbkrrqvClzSnurFCG1iSIr4FdORKwKIhVFMTvdpxJhw2xTlWXCa3TUifanBmg7L2Jqzw2XB6VuwHzTltnpzAfMK5wfiInUdXEXnwj5zHjiUgYyHmNz1XUhBFn4VIJqLhWJRDKUwQFZ8RuwoDj+41yz338Wz99oqvnbOJJfJC3ecRKHhYqHICrGNpLxe1cenafY+UaKu3G6pHMkO8/FY6rmAhYHz134ugynnr8C2tHeqhwFLDS6K/d9lp+bZvhi84lWT7HFugfUx97LMrQeih9QfbKuJ2AWReVFvp24FNJMNeA3S2dTGQiU3ql/99pNIvCZCR4UlsDr34StXiZkHrohUOJjbIp2V218XxyljngXp2AGz4sUFZ7HeCKX7F7nDNkweWo1FxfRZ5sykssgDDz8jSzknZIP86Vo9qkEvWv6IvzJkcN3+NTRHE9RFUlqeaubHZ4XO6Pil8udf4ch0YomCT56EYm0Xmf/tb90OuwMxLoTTBw9hXebh+DPtUbELl/sbrtPg79APUEaEIq66B1cp3JqvQaHuQmsEzMBaix94W62To50mqnntYkC6OpjCFI77WW3JhLGXduh2g6eB9X2hAk9KkcJ7+ql2F6u3bt0xMwCChIfIP12KRTViKbxLwtEtiwQSyKYasnMsX3YzY3O64xawdchRmXWmKoWFGakcY10iIUjmvFpfFuVL1jLh89lVh+zgTGbOg2RyKyHaqakMBH3M4eH8ffhhAHny11VVG3hesQKwUCnsuNfg4Z1xPuzRmG0NGDmBd+L0QusI2Lp6bo1kLWqLBSbDURMPOqVf114Pxolf6Chz+kkOw2iR/uF6vjijSQx7Mb2AvyVtrm8Rf8Ckdzx6RfptIgi6Xv9nYFQkaoA7uNxkC332jJk/6mL/67g7V34O06brB8yNoOBURqTpwxp7p0oQ56vQXA2rWnySRzcuKu2oRPJDFOroN8VEFJD6iSdgLCVvVAgvXv9Kb5p1WotQoxJTQtn2cX4UL4OuHDIMm+k1VFxPEtPMHWA7da4Z4bCq4DNNQ6Kvw9S0RibKD5nzox/fpK/1rTAIgIQKYxhLwwSN+zBlO5of37vtZ7RDlyBv8HqAnYs3xLRdv5JO80jg1Py4ItQjXjhrsXJ0naOfqKk9NHXGqOVN3PR4nEzQYavL9qOmvVeP0B3FDXiEDKs0cLFmk8/Sq64gYbKV0VXHU6Mebq5WWhQh/cr7Zdree8kphM3S2LLSMuQ8IwFe6bZG218l74TJF/y0rqs6iU0lZPzeLB8qztw6mSF5Ea4LjGnsndg8Y2dRY0bSiMUHU7lPaEO4d14XVuHht0+CULbrrLDvuwvr4CcykY4Gfkc7NalWOXv2SMKJJQcpGJW6bwIFe/s++WdrOl/zp2MXJgiGOWZJuWxas0UiBq8hQ7I+q0zuOGjmhYMgdyHQ5Hc8VhI5HSfON2aKayNswJoLW919PpE/9/obgRZFt1N2/bwF+m74Ncmp7NFKPA+D/mzoTEP95vvjIhvcwB946X2JFBHU/ibdZtnB8CQ/k3lNhy/Dq/AZy3RQRkArybkYoKdH9lCsGtGDfiffDGnBJtJ6xeTsIxySowUK1coQHZQsE1wLPGNzJTVYkwU2LfMWpMjt+3l7j3L7oGtlbsCNj7S39F5l+QBd3sU0izWxDgIEKSpvGGPB/i5g2iKYDH1Kq6UmwoSAU69sUABKMsdz9gPMRQnPOJB2vd31Sr+yyOqhBFAK4xTwF//bY/hBJMLHj6+/pwuhjatFchCHRzhuXEm+G1iWZDWJuUvSHPZKehrTQDkaxN5034Eoet0SdqYiOF2NAXlFSzS8qa1LbaxKxqwEJky1LfcK0yI4IjWTCS798t+QAjvLUirwxyhQDguqkb/uBCP8NFWKAXZ5hN6b8g8OdtJ/2iEbq9WA08iHukmcQPmRVH4He9U5BkyKtNQorQ19KaQBHcSczryK2pPQbb29rx+h3qLka0lMsA7CkiqaKQ+1kdq3YUM7Vm1tbwYpKGGvwOv7Sm4Erxukr2qyw6Bc1VjrsYb+/Xxu9OkfziIC+cJh9FPu/+wKQPQXNRhGPkaV3u2AK6wkd/Hxf4aKIhKTlWrZGnx9j8WJzCcTy3pMu6wtgSFnHlrraVbJFa9dLxxQ+OG/p592CmqrtsyW5WcMH6ejeMHy24La9Y5q4aHQZK/C60twkDeKVGbMUG3E0Bv5eo1Z4fR4tE3jwq2xtNNF3mIQwiemuBfxAhCV0rK9yL0gN6JuxcyjFnKmuBfr+HB89o4Xg98/3FTLkI1BNwY6LYwCfi7b2HBPdc2VqzuWBImVKdV2xcaq+xWjXxutP9QhJvuyWUl/UzFnmINRVfqY2SbtrVnQpGDJa1jZbwjkjlzxBV/9eHuklSXjNpmpONsnWvaD/H/swNXwk6GYRmltiZhXKZPK/6/0ithM1TbMLe5VKsFCIUswmEiexGUaGRS1wcjRWu2v/6vjlXI9CD2faBPZ/JjIjVrB30VyM2H2joToaQ1AXTj2HZOSw84YQAqWt3hE5wS6gAHxcGikXvSy7VZ6CrTqFQy6wVmXqeCJTeUPoo7yjaOIYMK5/dM1HXhCQIsgBBWxyNJW1GMhsUpTeu0dqYWWEgEuXGaRb+W4+i9tzBOMb2KjVHCwCh6w49OxgAqI1pjI3mZgRCRtgfHbw43OS7Xgr1lkTNTBvqkiVgJm9SFEw1y2p6ZhacpPRwulLXTEzwAxhfYNpXFmW9TeJVaEhyctHMcNZRwjB+x0+K3Si2yvwDmMqUHNHix1sVRpj838Bis0HFkYxeiqmYmzPzw4W+TagdzzVkycaI8n0B0Z2x8GN1fRPopiXCncBLqVL+UKm0f9y16ciKoS5/uesxn02AVMsDvZWKNK7LEFs7tklO7nyPE8P15p0b/vwq/wYIrVJFlGmdXcrf4QAzFg9CXG5SPBlf2gUxQWwYtwsJpzpFhfk4wgk1AcRnSFGbxVpK31g9X3TluFgNMhZtuuruSQ+IMNwGJAUAADm0AQ7HmPVubxiopGJTIaGkcfxRPUVQ3L2fm7Z/AEyXC0K36pdzmR1JZeta6RWhx+tHzQ9VNRexDz0cLcOUD8ONapocnJmgwTrphy7NEUQhk8qYoX/2sbdAseMyMHx7zsipFJ+Su4eLA4/ygUzg1pJd54hQV3VZ61hj33YtXsjj8N7w97K3SI8LQAhhlvJarDJtTlRaUA5OiTSfiCGUMyhTYBwQfZZ+82Ws2eeLD+hccS8SrhICNDXFrYRFeXPK0C43lGxZ2mGmzMYTgmCpPRMGuy349P6XVBsxsYzyQKPurLPL7sGR7qLWMk/ARPeOccbC4C0thPcnAgZKVEzmE2wdM1d6sddy6CNM5QucfGqT8eYiO6zPYv1Pmslv0+QmXaGoXToPBvlM1LoF/6TGWzX7gz7DoD6GExzGrf/sFO9d/8vGZXewZkwGL5ppiQTbt1zLw5SEZrXwj+Y99PaVAPWNYiOLh263tMYzmnyedzGMJMcTkMu5GIG8YMZU9IeyA6orpZ4nOpHfFv6r2ZLLTFknzvvrDGHhPlWELO7GCT5R1RM2JW8ebYFWP65QEqITU7Rwqc6pueJw6/2WjqxgiLc5gE2BDyf/G9mqXVXc4NyG6GaMS2pCMgqMMSQn6dOw/qVUBojRbcylV8bkiQHHFpa9mFUU7vCrBwaEFCsXHckjX6/3IUqYOOc3rdykUUl74xpWOu+l8IA7mr3zr1NntcxT2Pni0yIh7fRNWYFpJkdrOOe+U2EKzpBB414FLNNjjCQuee4Alq4Gei+/UwFDRKtYar1IOrsVutt6geI4BKH4/tLyya4XAFyHK7Hh0t6d4+aDsZAruInih4r+2YdVe4ceo5GIO4Ud6ODrHiQU1lU1egrpX4dIITBfujaHxPaNTCv++pWjjR5AgxlntV4RiJWOTaiP+/yExzv0iuYaNFkYqjAlohFLFA6b9bLi41IjD6jAhcfIx4kXxrFXS/8dzC2aTSjpKRWlxdASjK4N3ip64oiWNdLXbwuZWt3LSlkFSj/4ryxzc0YBwiMfpWcVGChSd78tW8dZGH0M2sX8m2QmMoCkGc2+3an7rs/blMk8maYN022v8lJzG5s62dsTMyvcSqU6Gr+8+7wk47iTsUsIXTYgF45hjl8awqTmHe7I/Xnk0W0Af8AyXSe0sglzwLT497z0h8XD5sq4ONisP9Hy/O6PVhkgEDJ8rRi7AFuU0K1r52cui+pCLKOW1rmySvZ0RGnxIb2l6mm3AiSjUNPVJtQVqVqcBdTGxbSswx8DdrAWotGUe/VWGhyx3wsrKcXIjS9FmxohS5LO5v0JSfqlJ1pZxuZ5kYUV6j3Mi8kAcY0LZ9L1jMg3pLxu8fPkIlGWfEz95sNz/dfa+YGybtgDbAHFKCh4p49WWEd3yp0YPmiz4L0dNNUJguuqXgqeF1X2Axs9ZnQjA2JADTlEGj55h8NXBTkMKxNn4ughlxY0sv/P8QyWX7lc4d47jVAzTQtPHCtJLNm35w1B7qYsxdvSlVnt/iEdhUcIRhRLuAqYWpmsmeTskukZwOCqRJVE2yf/Ia2Rg5VZTAmGfgMUbejpZJOrrU+csslSCkWkxniGZTiYEeBpZwjJm4NXrjgeemUTNTTktf8MeS+om9HH2+/ShdD62zF4s3pRaxlN3qWosa7FIYlQ6Zq4f0h14uKe5TLWGfIMx1bFzYzoF6gv60wnWsOMwlyExfmcLUnPMpSYbzJgvMEI8lIIVra5rVZn4RbnW+fftwoId//LARovQpoLy54EbR+Lk4zG3XzOxOaFsWfOSfCrDQ5icMZrtMrWjnrUvmqzI96WjNAFrngqUbxPExHlGRRsB051oNxpoua1emWoziya6ptJJl2l1evXoHlfDL/4rWqC6jfXaFAXrbntTKP37EQhss7gIjtX1saBx0faE2bCL0qkJZm9wKUiik75TouIFbyBph35qMGJ/QvMdHkJq4cOkq55oddec01fZvZkTbnVq9juxHKmh1SXclOfxwgstusPU59j1cSUEExsKtlAhQjC97ENXCoAwpynRhQGkW3h0nZRdGdk7yIC6x/Ghd8GGv9GQ8gJ34b1VosGxs86NrijCtisruZiwCh+XUeN7Q+NJsFFHxgwgZC/FYprnBPZl7j/j1eQdeZvE10Yjn9ze4ZfxzGl2/asER/+XNgAi7NrjaVhbZgH3jExWnSNBF8EwajSMjW1Sd8w6sx46AN5/qzhzd5F9xBPWscwl6Gm0ypXy9pcAUkuqNW55W7fM0Y6JBNgBHMiy2ZrYEo7w1fOOBP+lYJrsraF6Gqeo0/uNWp1M8KHRAhCBG9AgiuGaW5zL19BIF89uAz9CQMgkZfSuv10m1C7BQvOWM6SrA4NfmcEW6JCA83MfcHy4ns5MbFi0zuea880+532Twj4n2ppzhU80MUVjIoyZUHNAPytTpYNvfY60EYflg6NbWR3qYXWTrBAocI7RiY8GHoYXxKmAnbGnpDPL1YgoX17tTWJTNCLsOQobEuaE2/f49IFI613aIUfle1iVUwMPYqN5vcueZkq1sew60wettaxKeCJJ8QaoR4Ks/G5NO5MmnJ0X8Gheb1FVrQhiEIA/xr2VG2L21ftiyorRVJ+KpC2XKmuueHNhc2QA4RyaG0xYhW4LByX8BWMm36IgLvLoZm2WNAZqva05iTOz+9Eo57Bu46DITf0mDEPfkk7nHTYXXVKuOg21QbANuQJRmR5ArVqpX+Nbm2YkDbOetOWzsDSTYAyzo7bvBelG3T/WbEykJfEkI7cZn8XYupJwFCbizo7vCgJeNWXWayv3rQ6uBOwJJJQjzw7fax4XeWmCMBuHTE59WurLsZkV8F87+Ld+Q8ZDUlI8Q8zok42/gOQQ0m0HiOu2YFIe/kxqzpv2khEDqR/Zqe2kWusFvboYQb2MXDE7i3ldHkKNBbOYfZDScfozYfVZUHWKCrne7o2KBwBMopblUI/S+8Lwc9Zq01vnZdWZhBnApXew9YLcIIYuc8XJ8MIvCCWzyGTGPHZGWstTuWcmLnrDI/pw+UcExKGKO/gvJl/jhPanx6OcUQc2LYclrSQbTwfoZ3gohorZvAN4wH2QobAXczJzP/wiYOeRxICnBjWLsvcZC2/xyfvOPiYZD4uD6b5f+HvVdcGr6WiTbzUcJ1sk/s8ESla00qFNcPoxAoclJ64r1bRLQQ4dtCxbHJrMHFz1zoXLZqWycf5bsHnc66naBuyKkk7793OQb61aE3oU2xruc2oW2UYrqOD2VDvSc14ZuULGaRO5tfzHBa250GtWeXRA/m3fxLygc905AlAgB54TOb9RK6PDbQyMs/bXBRymsidyS66xjnwiHaBDGO3ZTq/ARFum78K4+zo3I0qflQNolQxZjoEW4sElSt/m3C9pHvoK20DShTiM0zvc8SF0EbVwVgQgmdOaJpToq6zbGX2oXhYWeJ/ZBY4+SB7YkscnCIQlKaI5PJevX9jL7TnjMiGPhjPoOnanLFFM7/Js5sWnMCsJEWV0J5Ou6C4Pwy2HsL409tHNf8KS1CqCzLJUFNfto+P8eFKEpvr0DUPimkVmF35aECCjyxjsR4azZJ4rYiq1qrYJD5x7DuVI8VdvRX1n67imtzV8q79syi33K8XIxrfXRt+Bs6qSUl7V1dNwYPe34UZynoWnumFL9zTlTHCz+QYwmoPXuwu+N143Idnj/fH8HFlsCW2bm6AOWFWdfpvEouPDsWOUeX9zkm6N0FsepTahBQWiLZvBOW3wOePEwrGhDnt8YUE5XsHFGhI5lkczQPYW8c8/iK1LUilLI/rDYmgv12L0rsEMr6qGLKtTjE0f2sRQGCOWHEqjzWmqtRfDCwEoAr37wMCxKv5v2vMdddJtQelRRXBOq7X44lwy9oDsjiJxyuQ77ipFFgEbw71ipzO7pBtlKlAcoi5s0T6it0N3fTi6DAG2gWng+iQk6MumVP4k93H2Ujba7wobPVr4TWhPYBIThW5FWeY0cb5Hk0nDg7l1YBvujtMDnjnkDiBMvgzfvRX2qsnIvKWa29nRsOM+yIIcef7TtI/HDx5qTpRV+G8qGNHz02iG4BCA9Gxjfido69LoUeC4ThiF21V9e6PUdjIlgPYioj+wg6xdhlJfzIocP2gUekEQdLiaMHVePPfaCv/R6XH42Ta0MMltlfVHKtWkMqHwzUzC/DMzAIEvYhLiYU3MxFfrruGzeqSYNs5ir7fU0KlIecx4zxduyumc7N16EdwmgbThTs02j6+kjobLF9yCTXpDmEfaiRtpUNs2oiD+IPH5m50SVydOPjywZiqhx65QEiLswY9KQu9iHyqQKr/VNBGdY3KtRpUhFUffexW5mS52tuxaModbZhYh0+1nRh5kcTadUFXf+ySmTo0vvRvLkm0isahJVS+KaZEW9LnvGOc1nrWhevXHln3QON/zMH3N92nS3KcWDahjQPIAIL9U7sA0Ww5QckmvpLuWM+BbIfJnpYrgigz2qf+7xgvbXaoe0EXtcl6iFnyFIqNhq1aPSVMyfH3nrV2PzaI2wm02/cz1dGNClPDGnnaX5u32Piodxz7VASuZDStTdoAdn8ogU7+1RXGFD+/td0klThhGTFpmQuGjBC7B3ftB+w2Cf7cA/9ywogdkC0r6tc6Zju3pMfxEnGi5Wh/dfam0ev5CAwmS/9UDNJK/G3XDNHHXe7ohVUtYq5GzxOxQtfL3v35JiT/Qw8DRR8F5W2M8ADo37qpORWNYRoBtD6RTrH9LtE2tzM+W2IS1D48eSlXmz35o42LYxaF3TQ+8n/pdtXxMLZ2VnmJ5kd1MY4996tv9IdDEoeYnOWjrm5YkopTn7BaDqd2hJEjsgPZxpeoWnwfgkicAbM4kWbAQjgOH+Wb31z4FK3OrwOhXwHPmAczOrH1I2hDgGYpXr4LzgB1zx7k6on4CbgDX9WltaKO1OWNog1s7UdHPIVm+rM4A6f8NQmdo5aXtHIBh83r9vu5sCuXi54TOfdlLDkGeyVbnLr/LH8Vasx3wAcwtMbhfeg3JmVioXB/7kBb+pMBEjReO7OVJcNR0THh9fOtje4OlmpznB09qYbpQszvMkdAZvnzY+/oBXYQ+wmPh/PFkQOHnWE7/ySwULdRRCfUOCaGJ7cFJnDEaWAaBrrNTcxysvE6HfX0Ox6g0Va16FlTC7f345JGgD3Lt9iYSJfHQEuF+ZxjO2Zrcye3LIIRuR62OQeNB84aXEnS7eRPvtlzivh9pKo2A8KyCKViotMH4dO6Jy8zULM/d8+Jk/P29MsVqFopgvwVR3WV/5e70ZuxWn68j5xZnHMD59vrJJ3XZvfz5Kc+ZB1ob9Vt7mSHiEaIE1BzvdiocTxPdAp4RaRUnheidfpI3j4aTYvIg2dT3yhZAkUuB/39wtxu+SthLCIgi5Lp9npGcum7CLDWhxYjITsZgV9xTgYeWHGZDwPGJ7jW0BF5SLlpGMaML9AIh3pUf5MD3qmfgCF+bBAHNdmy0CFzT8rnWUDtcge4OmwWLSes3CsOkwvcieYMYSDZ9HcZ8K7zqGN2G18X5VDJjBQ1zkoGtANflR0ioP6bGC78iyfUJq3uTOpSQFUfL6T5oDn5SfvvqSpqmmNh47xqnK9U5EMP1FxX/XRGUANdUWkS8pzliaQdS49WFHsa7m0m2pZoxNnpZugQ7zh4xykLDHOGULzfBD+srfnKkayW6ho6paY/nq9+03XUl6oQU9GKtvLc7QSZEL90raCUf6HLUvItxJBNBd6V3tYwo42P4ARjEHO9/WEWjRsz2vxMxdyaFpluAwLFebkRooKQ3+BbkYeZ+YDd9zuMLThllUct5LUfbDlCR1UxOQ1B0UQk5UfbGkxiF0V0WexgV5eweGKZ7MEWKMn07YqruoBjmjY268U0Plv8kFtmSCSZJqQHBQc35+WMO+4V0D9VUnoja1kxf2+4RNO857aRH4r7LxnTgBRxvBSoxVNBiXMwSWiHdcfXkwI1rN0egpk1mxF5N+coL4LBKi8S3wFjTuywuBB5GCSjaHjsjpanc9HwzAj4ri2H39+MloAiBrL5K9am4GXUdcfm6JXUsTqjsxxoHGsXRc28Of2ETIjRW1y93/X+ZV6gWM1lKgKNs0NRe7GMs7yyeHacmceUEGQPqCmY5CnAGNt1BWiSYEvw+4Z2FZFoXEBvOrnVH2I4T+GBOBBMZYCvfOOZZM6MWT4ANwf0JaetIfiCNWoeko1BxcDvXClzEwYQaX02dtLas9gMKQc21AUHwwX2BjTAFHGeBZnNh/hkQnhlvq+kMkrvXUmMDln2NpfqYHh468cXbhQcobjyzV6JcL+zEKkPQmZf6zVJ3sImVcofUV0TEXM51V5qcBsZLuxZH/QQ0ClSGrGDhjAjYb1NAwDYt55oiZEB2TC7S0VPAgQrYJq+88yS3psieRtpOrNNzFKxM0HPOsU5UiFPkPnsZTTQ29NYwo6MERuFO+NwPodZ5rYsE5CIIDS5s9IxQLlmefTEoSwxiqffpfjvTI9OA4SSVK6QS7RAtJGAbyhGRQxmF6XgG6kZbz5hAf6F79jWM01DevrMBkbztt4rvxXh5cLijY0SoxyAey60m874hlJGlnxqJh+xn1beFZoOOwrbGIF7VEzggIr/v48r+mOo2bdgoyh6Er1KjRQnyTCePpsLiGrlpT2BrPqwrbS/eEqVjhk81OWo8V9kRd2u+hcf+xaWyc5UAEh5KYDI4di4XP3nB82f1WOMiiYoIiLEIeq/mgxJgYtadLYRrg+ElMQbRwQbskT5TWgNf5YKO/HrS9rRBYAfI8XyoOhVeRHHN8Fe0SZFh4d+Z0iMp2Xp+LxzWTy8PJtziRr6WWSDuHCyw0aSn8p6T8nMfCWmbWA1B+TAOYZfxH6Gcx0k7wXxgIlCt7zwX6fLras25vD8mdai+PyPayhq27n5rtEaiVKIkN3giw6ray/3czVMiC8VIuvjcIA8DipsWoQ3GsWSnlBNkz4zkU16eGmvPfFjEUy6PBaSYPsUhslseEjQ2cmVaL0D+iKqaW08kS2DLSOjT97TxxdXTJFDzmN72DjmxQCftQ6oZMxc+TsWE7JlyDR4duTMQC69CoVySHkX99QCY7UCoEQUsmoSdFByDxLpZTFksJG7Jbx3b7KlB4CpeazwnUn0YxYVlDUO1tn2k05shrovE3XodJXAQj/flcV+8I1QDEc4d5y3haoZlTbhwv6DkO8RrfZDWOgRZsgdcaWZ7IEexw5WI3Myi74UdIEspAlGK9HlNO6/J08KKicwN+A6vmZ5hGkwdPKEa7vlbdFxGzmfbPUF5o9PZhOztdPvLJFdN9YthWiY+BQqyfm/CavIX6f0sg0xJZ28xtG25h65k33po+daQP8zd80xVF3Nqp6O+23MbYkpem5Pw4TavHvl+j6tQZaWTZzCxV59Zn/D2E3OId/Y32NtmCSCFjGsbaPFr3sfsU3U0v1pLF38seO7oaOYwBh4MKbeOnHxXLMn+Lb+gl8XkW+H1tlM3IAzbCOKfs/TwtwH8c+KessGD5WcglkmL7Qt1dpJvPhmIA78tdYwBt0LqK34CYUPNGsOwU7a6UfipYZPBi4qy4/Mr2BwDByNc44VlXVfJ0T4f45/d9R4IUSfrjyg2OzCNDRShGRbIPjeyL/EhIJ8yJ6IfNDjHBZdVxTFcdeULGyGkTS4viKjkYLl+9ysjheBbOJT5we6Aq3opzOgHTLIpbULNNCsTxSc1gWS5/tuupwj9sIkDEeW28Di0pChTfkDXIApwO7I8Pp4mS+kGIX2CJ309H9d+rNwaqv71D1xJrrmhMSXcWDENuyuOL2YN19aZ125Viy/CJNluOIa2HA9Y78lBs5kh6Pw0RQ9l+CKk+L6yhcatEfmKU87Fp9MO+k9mrQ2kJQXWRkdkPO4H9VPFiKiMZ3/9rs2ZGLDkfOYbOnGV/CwCC5Y15XvnZRratGREjhN/NYhCa0AH5JJ6tYE7wdXJPDbovQ8TlxemKpWjURZCoQd+e5rDpUuaBQbNZogLSc1Rlvq6neExB8YkCXeykvvgWRbdI7obLFv8ZXWGY4Gl+jxJClWPSRUYbBXV+mouLZ3cFJN2c1CJtImfi74B+TnVbhqUCgronBPMxpRdOytyuFe2YNA0JPlPJeiFWVqpf0GRGHxdXYPzWJGx4gH1XpQqlbrg8Xl2/Hxy117is80rBczC6Jxjcma+B2f+cPuQUPWMeJQ/hf6k0qHeNhvLQD4i8aV0l35X6Qhcl9+9gSGBRGoyU4aplR8pA61DXcczNgjjEmW/c5KPZI47ZpB9mXEtS/5t/idfP3kbivrWorrAZ3fSliOxBxgOpa5k9P+0jiR6//KceOyQMejEzV5u5PjarYLVrdm/TArfJA0pF9zAl3+1tBBZfD+8Zk51RMCFlavMHB6ClNTystNYrmFD/PVIJxXfbLjenPZl+ZcEGE4xfUsOprXvXBM0rFlu+4J5MB4L7xDRb3ri7BjxKsvfsm2wZc5iajWPuhzaigcdEC02wRPHGlpGietc8V6tNI0eLiE6Gvze5uLzYUpE6zbaFn4aSsSrZp42Fq+MFvDtSCEnsU3BQJKVT81QbymiDpB7Kik4tv0BeVz3SnEmrPh/Skvwn0F7102cAmj0p2M2CKZQvft+M9QLycY+PAYtxdwagQVNqaPp2GjmskEVakPmhxhATQx3SaQv4fjC88glahxgYmiHXvaoCPjyAmTuuenq9lAi0pXBgGpOyeyxUzTg6YadPTTqWh94n/L84I7Xyi5dKfovMhZUgUza9Q5nlhk7wXNStRB+HR105mxUu7gPcpOJ/LWaJnC+hvwymKVbenlN58llUuavnUKr18YFzK5Aowgdi367P/aH0AR6jWm5/aptYjayCWqMVC7cS/sjrFDit3koPPGluMWN7BYzTurDnKgOw9RF/yFXnAaKFOTG7D/6TDj2j6UDgr4xMsGbRd7aPAOcliVIS6JfwoDwuf+RpzHJ3nk8gWSCdu6N85UEoBUTKtDPrfSSq4MHDEq63RNt9F+e/03X2Rkv7d5Uj3jKh3T/BcQNtb0c/Ec97R6IzjCjR+rSal+dHChQiKk3dw8eD5BdzBCpyN1KDo4R8GYAi74ahwbCR+97EIQl+5L9h5XA+hwCTl3Cv/gheoaeC6cQzLifJOIHAd3iebj0z34WRSqLyJxRizVm87Q7xhptD7kchJ31Ou2hl7fzWOJUvbivbzZY0LxFhLei7yEsHMb21wumoolMaPZpVtRqJZFPaYA07b78UBvkzwMWT3isF1f0XQXEhXQCTD8qtBzEGAHvEuRZrv4EG6dkbU9F2RqPybmDX1EHbf8ueaFjZUhRKKnyWuavtmrnaHoNHnV8vH6UmWXbTmhS+abVCZRtEBHNeIaMJ+kXyJjnKozHDBFLvmtOSjIaUzTOjYrM70o2FlDnV8AyhqXIjLIBdh4fbahqZhK4ffKnghkHf1KUYnvi3h2UGFuap5wdLTdOpKJQBmywJfZVjsqLalKMAfdnCmQCmvDydHI6Bechr8pXPxliO3f3mvZ26jujLOqIaJn0hbR192y4dG/OnMo3HhRnDcifQEmdAtBCyjXly2fC35r40EQOdUUwirxpBFYeSt1dOa/Nj43owlksWoXqQYyyK+XCJidQYKCmZmGrpwRgZg5T0TFQi0HltxYDlDBOVNy2OWFbb6yQqtdcSGiqKTMHvueatUdxIEY36s1h+uYB6TXnfVoW1ntTbOQvU96xBoHzVDm71xoUsFydVu37MFlRfgzfVYJqB+33d+rFKgLksTTUPDvXHykGyu0dlqgFmW0nfwwzFTSjJY6FQh3KgjK5QIo4nP4o3e5iEZHSN21+b/PcOC42UuGHxb6+zBbV4h4bboNxdxjOpTch/kVwin+7wX5YpVrMu5Kk3Wzk2q1+SOTxQXahOcROrs6bdLf3GsWmgVIT0tM7B2mWKC5Y9FmWk8eF0kGcZmyEX2l8kC4lm2cbT4ObsoT0nvTNFx7T2PBUPKDg2JB09mZGXteAXYZtzqOo7qgkRLuL4rVMGiQKV62ggSNHYKiQf4GJpIAAwaCOQwYhC+Wtxwc0AZT7Kvc+5vapUGL7OC0FIpArkcVXxNaN9ws19KakMcq5Lw4fK89D8SJLVpm1ICVueDHliu1PQDtiglCUq8lF4mdcTOg6WzE/el8tg5aYpvA1VuQ3TGv4z0khoABAhEtIsibjwS1EESj05nSKnQTqMz8Zb+9f8fPc1ZnvW94oY88ZjOHqIKTFhrjZoO5CujNhyrh+TVUlX/I/wKxfDfdVe5sAFKpKVOqzT7Y2AUA3VMnh8b+Ev5/LWy2nW8YRHVurPBhoNMe1fSUdr/EXNiHQtZAbsqwKGMbhwgaPrXCsM13FPwMmp54MY8XvIWyXu+SI+2Mn9DqCHWHzCpPe1R4pCEoMEBeIHBZb2fUkNQ7uVzDE3D+U6Uu+9EKcgPxnWCRkSje0/MRraAkFyKgW2FGkaRv4k2bQ3puYYFLWf2jUM2kLOCrj5i/lMY6mj+acy9bsWpmlEBJn+TnQHojBLB6bD7RJoiYYUi2H0VarSduGWvifIGpB4OMX5nZoFrffdFD1F4UnN7SqZ3pBTj71b7Dgii9EACOU9zXLAqi0NmOEogjtIiLZPy+W1RsJ2rpdIqQNjlNIJ+N/cV3YcrTiQlVHRMdim9o4v2+aZYUGGmV+hiH2fY3eHwgueVyyaQzbjlYE849sg6cOq0oshvO/Mw4JSW5VY4I+lZ0fprku+BEw+MUPbCarArkA9NUpW25fvNgYID1KlsnYjXCgnCruGSd4DBGiP6gPn9zn9bZjikw6xJE4gI/OiMrfTWB55yCLpxPG5ZNDLmfyhxM/BLxKeFRNrlbnjzKLfr2hflKt4DghNp8wWo6LyVoUDabpTH34q20NfjeWCu3FmPAfTUoJqGfu2RRmp7XBsoY+vepzKUkBOaG/9teI8A5es/ZybDClOiICoVi2Yx8KZmSHDqEsZPzJTMObXz9vRn/zGI5AQsEzPdbdM2FQMR7lBtpLAHwjrVyL7AdFdEJETyb6xVVYZuxjmfjgRyfkVjYW8F2QQMCRnI29JCtwSLJGJO2WAQMEVkN7BhVe7qYeVXak5xaOzUH+pzAKDPXSeozao4sl/o7V7xXCSxGCdvhB2S8BM0K7/G6t//S4n+ZwOsso/VCKE0JhnliKYxZlgH1UK0G8lOhvl0k4cDqfpVycpiAUbXksuoTs3BP3VoDEUN5RVJescbWopj4QkkKZzhD9v6wZa6cUe6THTi5mOFx03NU0RH2pFFWYUpN2jtlz8MCT1XhXAmPemaobzkIOcvXV6wAYN9LGl53BwQp74G3XIQhu8g8NW8WKSHe3wHOvEpCWcpQPfL37AV3ThFxe/OgKVwXeerXRUcK7tCz80CnS89qlZyTEpwYb7fsdlr2JuQN04v+q1VgI2q1aP0kdzbuBkqhvNHL8ERUYMlA7RphR3NcXB+4s3JCZPohbs/FfQSsFi7/5uZXOIjQ1Rn/GrARA+3HuSbV4kClTrAi+hjzkgTzlIurJv3yG7wSsJnLXOM/QBYQOj43RMHNOfYJHZd+SEBhzDL0y0aLiz+9cUAxbLMl2MsAm3ozus/bITplzJNDO7PvKdb8OnBm7vkYY1bEQ3uHzP1q7ahQHXfBWRj8ug0kriXMPcxibh/1xalHHIcNPhK+6u47MKkxoE7JdytWpOfPjyMaAKsXWqUgohXCxMMe4K9ZmXUo8zpm2Zs4Mbar/atFAj1oZK4j5Q0vFKQ32mnP3XAj2M54ubqpFXNzlgsOQf0v9mr074z+ZuYib+2jLgbdc0rMx9N2VcSbogWkZWU58kFJqakJyccOD/CQaQUl3JuUY2gA57/B0n8o7KrQ+81Cs7/yiTVao+qQ5PrDCNLvVoOv+DIIvd7Lc+Tyw0E1WOnVKXFVp18b9cdPHFpMh5w6p96ch5pgedAyo7+4vDWrixr3Y1L+I3A2dbuVDufsY7NA5d37YWG+8KLoGPk0kKiczZKz3u4AprvMPsL6agzl1SBTHoV/AciFa4hbCVhO7gO6jbPHvydfuOn3cMeRVqV6FfcNj/WJuGzPOCUNEzcFn2E15af8JSwUkp9sBQ27KRfethLuGoIs7axHnV+JhRMd3EVfolqITmQZbEfzB17+0MPm0OtY2RFfcJOh1eoh1JtHKh5xogU0P+5UYL1c1AbMqw7VfmDxfZylxnsSfRw9bKeOvJMLbKacXot+OAXg039vgapHL2iQKTycUic1WcnStWTDzl9kKoxXhFzjJxYEkfvFXFi2AIAki9Js98awvJnHGSfoJo/QZg7GO6daPSe0sXMdVcP2QdK0hIymIJbJdOw9kmAhZR3CEMvlc+WnGAEOCMQaZSS5MLFoHcPs+1BWnAqhQPQbxOxOJTBMHalFyOftuXLpTHMZ4Y0F4pg8Fco3SzmkUsAd9arhmMwYKIk/Bu0g3gXxcoWWuEvjrPMxffGGJXfX/YGBEFRZfUlzJSP3RcChHIyjUYXCrPNd6salv3Yt2COJOMtoYCVn9YJZZsYAbeCZ9rkdSOZIutS5TwRHQPmGT0NgI132t+7VSKD1cZ2LTsDYmxK0i46e9mZneTEdoT2dWaC+Ckag74BxIc3qFa3XWNz8cLnXFe/YQ5DxyU+U4m6dp25I0aMoidSUHRmiHj373NwUS66qsxIJi2mIBs49dhPbgf/0HEP4dNz2Dn6PFMOrkLZi/vSDOCgHTNMB1vzSpUPmiErnwUIOKjVp27h8dpMnZKot1/TZLzdiReeCUSNjIyrZnAzun80b5Sisc/M8+eJ66/qQounRoWNjQzhz+SOIyABltqH+pcvimCxFSshOrcQDuhjL279yVRvEbMzz8HJZzHMKyv1BJB3oTxHTUJQyE3qcW/xzYi7z9e5RHhI4ozyoJSvmLRyzp8YMAFrgWj5I5u9HqJGvkP7Hd6elE5C6zO5dvMcPCX0+h7IwrKW0XFsSmsZKb3ay2JecujWNoI8iqyRjeKJRjPX790j6Jz3DqUWKzqbDhizxHPvnESrD1lLY1CSK9M8cm0e1U7Xsremlj12/SE/WbSCrotxdbj+E5WtKldTe49+xcHDb7NMhRbs5zGjP9/ITBOAGMyvrp+nin86evqJMfwOgk9oNx1mJSQcHHDqQeyhq6uT91WjkkJp+3tE7ooa8qMxBz3Fn4UA1RT5IXSHqjyOfa9GG+iMOJruXuGYjx/e+/KIjm0i6kS5IA7x7UOaPIEXQLITH5KqkesSwYTdwNwOpdbL9N6VwSvHYmPMwzRf1lxYdBVgoUmTppxr+lNDLQE3LYVZgvuiN8mNZZ3h2K+4a8yFu648mswBwauVPqQmfzk0psPkYBjJ1fsOwYBkhDcGWzhrx20gEkKdFfOCcpVCheHLRNNwuzMNWv3bvL3bLx8I8sr6ZHL3N8jt8w+DnbHJ0Oj8n/O5fg3SGUL9A8qICVDgFUM6FUq/M6bDZymZduMedXh8CSbpudzTfM1laaN5ta5XZyBn1HHDeGNaiccTsCH56sQ3mLA0eVRH/M038q5hxvF8LL5L+dokO/w/FkjDXyyzFiPczf5Eb5xgo7lGLsUk68rcFbb0ZOArk4rlZGnGWLjz0xTiA5x4HTyxZFgNQDgsSseloTMBwFWeijkXGle6Y9jqZJrimXJl5CufGWL1OqtwHg8kPBWlZnAK9UeaNYsEMewSABLxMLial/dUPWOSo0VGXkkqdF80xuWYjYJW9wnToumpr+nOpfc7RTOIOq/nNd1kXicuQbRsjdpmgZzWbXF3EQjFiQsK6LEzx34mnrUq+s8h2u145YsPkEyJBLUPPFp796yT4Q0iZAEtie3j99PHVrRY/9lAPCELG2p6FuHEuzps0hjKV9AFGf6gpK5LNy9oZUpiiLPQOevoFd0qxUT/fjEDpFB5UOVPx5fHt4EAcxTOmiC/Xa6ypG62pHYfcBbxvxbfUqVOBrFchvG/foK1um7S6BPMsXttzFSG5GKlNhc/Ba3EeYBeEQHkIGQjgpFkvfNMoE2R1zAdEVWD7R6/cEBlUQ/P+dGF092Ij56eV/e1dxlFnKJriVAHdVhEKtfTAp06p4xTvWGK959VtnqAHeYqMryanTuAs/eDIhWKfrLerTXtCQ8dj+hdnov0eE7aCfUV/tM+VZW/gV7xGkGtVH+4EQK4FfTiOxUAfbJphmhyTIYJ8Z1tb+AwBb9LefnxzO6M1wnzCTWZAQTeLz7SYTq3zg24EY8jfPcynTnPIA/FCbjzo1u4fP0b1w0Yklo01U2RoR4vuzQLXVu/4o9HGsAqmWe4KM4k5AUPYDwO8PUqwqAmeBSZwi7DaPYUQBlpORu56jPdqYrkDzQ5meuYlMfHl+c5QGG+gDeEZoc1hbUarUbTdPdw+p28k0uXwpTsQFih8sn+xZ2eBnfMEbEcAA7gnQqWrv6rr0cbi6I+m3aFjmJhN8u8BCYW32HVgoFYtUo+2OnDZc7sx7ex7vouvea6Yg5+vW9rw9+yMqYNtSStbNVE4mHIteFboSXXJdQkjNNAVzk7kuoatYcWSSVEz9knvigvouDYbmH9dVA+CX8e2qqWOyw+s15/55PVKvbyfVSQIb2yS+JxRN0xB9u36D426zjAHGqULTtn1pYyXynrbiM0M9PJBSoHqETTMymzqhEVguWouE6EWoz+dXA5jptm7Rx8iG9BBwZHKx/xVZB+CTXvnEOYz/DfiqmnPoopJvRcX4dOCt3MmZK8BwuoZnlPgkgl8s+ePzGUXNqdas2AO5o8FXPSfaO3LhcMHkAel2COZVJOJVNOq10+twJRbB1EJNKNSRQy6DGGwgN+Dla9Fha+TxFGUTlCR1E3oHBzGaMhDyczKadjd75mTx95Km3hHZPs58ekRN5QLnh7w0zwykLESNeAfKCSLhnfIxwd7LGl+tMUPJBlT1lV3o8ycDiHeIoUhha1f+dSF+VcQV7vym80R35X83qxZPatalvDWy91VoTaux+Y305dKiTHssrP5NeE46qi/VSkLffQAkYP1vhvnDC29QFQJG0hb1DRmF5T3VAcmaL1biyybKPsCtdxlsELLVdt1HfrOqdOB4W7gIsg2f0V4JPO8wAQDx/f7r+qODa0BTv8qQZf+o2apjNujfoUvXiY7lPGlmho1zJPtrOxzQFusqv7B6R/3fku8Pg7rkyuE2p/YVojc5nwI1IYPStjiPC/W0J2oVZi0gzfQ6QiHyO50kRQCGt6QGbIJWoe+uFQMAHramm9ul2p28wL48D487pQ8WpP1yus9EPe5pNPhDKQS6OoMiJGysZeNFM/i+m/Ks1rFTz+SUSzq/KVTP5haVTpaf6k+fBgDOI3mifKqQ13WeXrjGtYKs6v9dIq49qf2dW0OXkIGdXEBNa+0IclKvgyZrn2/A3LnP9AvTnYHK9uuDy4jKM2rFxczXOvIBH9/OrFeFDgSPSIaXEkmJvNexjWi/yQyLITiC3N4Z1Oj3+DYQzyV/QPVAq2DQ9mltQBmYqzFENHWi2anjMhp3joOYOopFYH5sdjqvm//R7CnWseALZm7wZvCWDclZL0KKY6wkfTUarWhDfAWBFLBkKp+uT7XQBTDqfAf1ZrcEmdEktyuvQopw1GdYR6BQAJWxhGLJfDgwgUMxqB4F6K+iboT126Y0YkhPn5iBa8dgF9Ds81WDuNU0o3ykdyTGH5zGFwY3or22sdiCV9l1mQJDu+nwi42J/5DgXLqT6RGc4bsC3yQju6eLaVRWbc1PjNMCt3nkwHOedY3s8vFFGALhg3ZbDbmknqXm6C47oK0HUL4tyMhSCiunmyTGDKwFQCc7j+3snbrNZVE1DeAJIu9rk2R2c0+PNK6mFeyJEHd2aQ0Y7+t4WKzIIXQQadcXwlWsJqEFIkFT/wdiAkskkuOQrApKPi6/Uic8AFFLB5PO2cZnROGhfjdXwxOiZ8+5KVr1MVwRxZ6yhih4HYRB0PWMcDF3G1xcDaRpPI/a6sxfw/ziYDqXup6Z7fH0Hx7dp9+/moKb561100OfLWNWcI2CcfQyXF32SvWXCx/BszD+LmVO7X49mRu2D+X361OoU/Zsu4iUT0xeOmUHMsxX++mB9qG5fhhJdaPNY6E6ToZHAHX9qfOy8cTI7YpJ6wb3Djk+v7oPNgbHadE2BSxeRbbxe6Rxh41CTJ3WCgGe0toGyHcdwya3QHy7ancrVfDA7p3p7+NlkQ6dkWBG1ehkp1goC1IvujHS3APVLz9gfmf3BA7eedTReY+ESig8G9shpaBRxu7TxUVPx+vASd688YwnUekkc7OvuznTiuPtEbpslz8mDjq2wV9s6YaAGQzVeRsXm4vn2lau216gT9M83mXRj/BNVlNtVpoGz+vwEOYx+OHj0/U3LHdvcIWsYjH6jtRlxBfnvbya4wt5LOSUZLFBnDobMCtMzWADbPCUAWA8ZkmN/SujNubB/uZiYejjidEKMduS9FWcOvTzbyI81liVbyXhXpuUL5SD6gi2m7r6cUZt/dG/TR6rHgz7JMKeu24oE1IeCb3syaWPejkn45F5DLuggLL12DSeieueVYsLbECxiefMHmzRSHQZIJmjEpMOn4Ly6f9cb1lJTghggPJSpzc4xAO4geHgsXhqeWkG06mRtVLzMxRF4GC9IDnNTAQoBadi+fFB0rKYSFArGqk2SFoLhBMGiRGC1cypQ7HA2lQg8C5fb5zMtpXmccFU5JLQBOPHL5DIgAe/cAodWT6c54lzX825dRZAkIDD/egt6qSZsFdD4pfCfc0nf4x5YO+yiLDE+5ed9wk/MnWtKOL+z7jozLWQlGuRzdU/fPbGWBpPEqUyLOpIJU7WqYGOxu5BQ5S1UtGX8dIC+tY2PxhjBw/CEAOOHPLL/dPGxpb3V3ZuwuKaHNvypVSVJ1N8ShXU06XseEdivY6rsGD6XEsro9XF4a+RwmpAg2nZtj+RQo0vbgmmn7CppUp+KVlEh9wc5wLC1puvPNaioFokhwIRF3nk3H5CBQDv2/LHETA35eQtIrpEaBnLC378VBfuEkKxM/fXDt9KoP9uOuMtVfuTkOwx4w6oZ93F/GUFd2bRwG3cqy0Zud0zGcQZ0fTQOz3l9cCMrWUJZeW7q5uABpld8Rpq5mfbRXtNc6z1VCF5CseUBuRv9nkCt3EpOPRh4BB/ObF2+s/ssOaVdAG8Zy9lG9Y6bCa2120sVEw38FvQJxR1USzcE8ehcxv17KZqXaNSMI3dho/3INtVd15KIFD0gOGot2fyUGMotP3jq4rPsV0zNGBhANL1VIMw/iyGuHa4WoC0p2Jrq6UugBm3Dlv02HViWurpXG2Y+MTYCKdMS/lruLjanKAFzV3HgBXqmiG76NrNDLmzG949hQNLpmuEQc1OT7rHqb5qVV00Km+s1z01tI5k3cAHjXXqghnaTu03UBqfZv8Gt6uQbdpRKQdWq0xcX6mXBL3kKCm6yMpnZ2/2+vgPHmB7p1e6/b8HBbH8k7KBcYKdVLVoE6Nzz1zRwuyzQTzV1vsMGVKwoUIiO1peZyYNWIosj0tmQ2Gv7WfLqgTIE8Rub9AO0me5ElSlPxi2P9E5/FDNGxScY1hrOKdKBtyCI6QWtnln5jVpJR+J9T6KaRejBQqe552fBRukW+J4MMM5eoSiD6G6XtBrvR+ovrZnZBJqx++IVE9lAsI2Y8wGae7GRIS88Seu6fT0i9VOaWyNQ0nZzspNAc7+JV+wFNF+yOkWFRNm7YIznP2d4+0quUMPiwikLpYEAOZsoQcMbo19jS7UCIKkIB5aQ72Nnjezm6w7OvBofh12MSoyjruNHRO2umusuFZ5CccPY4b+4sgS8Q67aTe2RsSQeBuWWKnEE7jG72uqlbiQXwPO5j5WLqEeMOR9A9tbI+uImujPGNpMT3p0qCMM/tXKladdcqDgiGOHEHfaOVahdSEgzpzzcJA5iCpK8P0/r68nenn/SB9UqkMAL18yjwY3Xb8IjwaPhiKSGjGchAZO8sEgStRpP2TsOdVCNzWDs+f0kPQb9+7neSy8kTGMkzhF3VzNwZJUFRCRMCN0qxAXWeqk6yRhEhJzL2983icLW+uuvY6JMpamuSPj2Wp3qVhwKQgq69qRi2Zuvy07R9RXQP9Q+EWoZ4BSDuwLGSX227j2SLubRm/xTkI8wSfBZCwNufSq/a9KxwZAiS+K19cyE5N78b/8g4eCgxix4VjmvFXoP6Q/hxMvqKMScbUHuBkg97ZdbhcwZiXZWVbQmUxewkGqEjqk2ytcfoZEONtoLSMrQ6HLpYaC0VgQnINfoqGe1+Os/W+9in9Hij54iZNbcUyvAqVKY2ES3k/ejwuHJr7wAfvgHh8CpvZ1Gd9YGwYkQuv+7YwGXj0FymW1Z0mC/HaE2VI2BPkR3ymDRP1seJEoML5sPfnZTeFuq4fZpqynhSLGFY3wNYLHln9KABlzLJY4tb7Wn3mYAvW8z9cLhMktcmEeF7KzNdkoGiBGamd5hTdob1e/TMp5gl8O5O40PL3goYanoEGJffB/rwuJMuN8Po6O1ZJWzaH5AxP7fKnXrrsFlH8qpNissRM8+h35KApoWs8WAqXE4ghaYMTAM0ODh0sT5gCl0VT6LfIsYov78ENznGKaaXC42h9iwrhdinn70Qwp504o+3z+L4l6i8tdm+EI3tnbBK/sswvBfKWF8A3pExYXg/mYs2EEmLbgIe5SHTbvCn/uhBzYfFzJ5OuSuA/nRU3eoN8+g1UryefnK4C2O+L0T0hD+NT3U7YhKWhKIbTh4G71MbpP7gWDpz7e9dG32s6ueSkWEbovST0ndsumVSWYkUU0ixE3IJJvJWVK+m6TyduyqU1lD+5mq03lVNjBBaH210BiCfDds39T29l1QXitXqmWMskait6W879XIaEjM6dGUvxr+HdqNrE2Gl5wpva0JQ42EgCLom76QriTTL/o3JBQ7ShX6FLHIA7jrr/ajiM4aooExCJA3cDtIoDgstGeRTvvvr/Wb1Egw9AZon/OhIcJsCoa5XoWuWdWL2/Bk5cmINSI94sfltUy+vaaTj4/FIrzvW99BcRPxRoBJOquxC5a7+DseJH0drqi4YGX9MzIMm4dL2Wz3H2/xHBSfruv1RFcuACirbCXUssN/bwAkkBlRm1kUvtvXOqkilObtmZJonkEpBTHXC5pDattTs/7Gr8qmLtUqJIyGHLxfooHQQxtX1n4O5G42svJcA+A8wYQMQwXzxWvq4MnFoGAfih+32deY8xIrxEspscZ0ct+V41fiyxM/9EAmvN1oPl5hq3yL2rQ/wI7O2SoYdBc5TLy9FhstV3RNF4HI4w8ebeSJyv6HEIC40/JN9SX6wg8wK7ZZAhNTnq3O2cXwaxvzr58Cx50H+W6d5w5Q2yd5JjGlK8RXf6dwOgrMd7W56cMPhT92gIgCkYWg7SV4dWgGE32ZPZD3rQrrdmvI3Ci1tr6uMSrlvkctOc4tL/OSc5MmFnM1bHWVmZt/oShuwQdx765eeOdHyjJW08m4mVOdwBZnTiiQXSHrcHABnjdLeYCwQDpjXlx0gpaCRLeZ0yhLllzncVpCMQbGTZReW3Sxk/fZdrsDA82BpM5mdG+N6nt21rTPbIagQX+3qAp4XVXXb4LXlUlMcD7gtJptCD6KfTp0DC3Rp/VmGv33PoXW5sCNnx3FPwzoz29TqESAvZH+bVkdL0PYUriDZ+GUl1CQQPbIRNkJ4rs1izSLkqMFAPYBPD958zzqxgwc7/aS5AbSyjK1R5DbGZI0jRCzxsi5RsM1eAbnp9/8QztxzaSx+uyJknjxcwo6Yg1G6uDby1+cXZAtMbMqaWvOYMvZe6JpEsJDruBd7juVsFlv/naI5iOkK42ZRgthI34zRpgZ/ocvjg7/rMRoKwxyl7PVT6Ls1hWuieWNPSD6NzxpcgUcYRE+JI08Xmc6c1iLbrdYvGcFeKMtbMQm8X6wjNTe893fwe5uZSAohPemCkCrbVI5TttfzO9n7NRyqOL+ULxYG4FulCHTcW/weJiocJUNyhEso0Cfl2yTF4UtxDDcoBiax/QN3NkTT2l7R10iAOGt9DXlSH2yxq9mGTZ2FUmIwwCbvs+x9jJw4O3ZfpatL7z5INX3UNjY6b+XD5tcmt4hWV9ow0A8jl1Hby/CHnvcYeleaeMSzfiOddfCr4d+/0x8ouiCoNFYCUfpCbOgeva1VnpP7KsKEudy90xctpGENWW2e1FYcwYdSdck22d6sPSQPfR1Ajgi1uqeGC+8Evmo3gHKJ957l8IPffB8Fts3D1IG5eodkB6iYVDCkC+leFhTA2NekfJelN6j2CHvsh6Zm1dqtlqvap+QgB0ZvqUs5bDHZYfJnI1U0z+TV8guSHtGel/puOdMW/vXP/BU96dDS3pk6gGKB60iYlvakeaoqoE/oRc6/FbPsXo3UaEUqj2mMp/J5XxoJ9ZLEpBEmBwVaO4io33gAEKGsbbuikPRM2QOZAoFkXbaZO39jLMWfurMABiPjm6AYLU4bbYlCUlZg5eZPjIhCJ2YnhyeKY5BpTpWa/Y7MXar+jz23BCu5VxjE+Gmc2EV0K+2Pbu/FYwLTZRCV2w+KhD4r6z9y8GqBKYM9hWSv420T+0lFU3Yp3K5le6V59V7bSi+k7aYPX6xkdE2jTzGgh1IaSPf3HaWs1u5U8XGX818HraqQCtExEkPgdKlC+hAsbQ0ZGN0jxpfzqeRU98kcdcZELUaXjDWqK5gWyy8c+vaorfWspdOQsfwzjuLxyvax+4vdflT2n2FmewQLgA0qE1pXKmK0+T0yCHdWCG5XKxRveYJt0+TNxzVTVGHnyUbe6gMKT1+/yVuCASd49vZkP/BOSQKvXa8eSWRqMD1DktT8TtdwvNPrWAxNsXGgYeH1BAS23w3SAlAZnec2ivCKtSd1S/rS6Hx1XApAdramOEv9jzGN7hT3eCksLIZQEDhBe15U4c/56wwQiDDSGQEpgx4D3QSXSv+JaqR8F+WegC0C+/lVlAzC3S2+QpVSQPNEmh2v0pwKqrepF2Fqwi37gU4EI6AMRnG+mekvuTuUyHU+Yqe4b+No6Hsz7kIAkHMAh/whA69cgJlm9PJk+SziXksEWhTf95V75yfuHRpE2ee3+DD7HttmtetLmNudmbV5XWCr1bkH+530ys0sqY1/omaUirIEIErb4/YUOeeSf5Pbjdgj6CFVgRfvx/t27JQ9dwHL9O7Ad/C4JVjaV90PuOga7Pd200CMdJhFBYJQuC70dOmmpyEYuhZGFWMCON99+7g5SazlXfWwT02gCo3cankTFz443Yh4bxZJlJBhDIVvqxxOfMyY6w9hoBkq9qcFwZNgBjO9bYzxmeC21P81rdZOnL/lxw9ZYKyLVpvhUrGG5tNZjwyw2bEWINF2SmcUjjv0tDewCJh8E3faZxHNoOLbeqkDVFl5DytWaC0iOw6P/i4p4EwJbofQ8UFBhf22lwufD0YpEAED37daTG+4Mf6B2WeJz581Nq9AxjNvbowmfMAu9pCFpuW6Nkn2TJ80Ai3l9GtZPrNWdoEHu53Rw5Ina7a+pBTxUq9cI85xyqEX9acdsuNrVkrgUz8azHrXGpfzSTEEAkSYDQNgQQJ6nH6DHrs1j5XrgWdvJNR+GKmh0uyN56zCClpphYZ4h0gRHoYT+8nDM8jNXAL4TUmDh/BXmmnhHylRgMHqgumPDhSqL0y55YvOFtinA4xHlhoZK8uBkkyPDn0eetNnAyc2SZLDCq58Si7YAGROx0eDWnj54al7+G2dacvguA10YN2I3+FGEaKdg2olSbSqV9kEOCDz1heZpcbNCAfEp/wpVwK8kWlPxonZpFYlIbm0EddCyudF4xRAxEuNEy0vVl98nyn1HxqgL568n/aNjFRB03OBtZTfgJgZVk6Hm/goRv1nFHL+z+TbdMAMS+Ho3+4bC/x7kPXbJpjWVff3UWYgkxxwDyc8ZStG/QYdIHdtA9OpDgtdUL17JWwf/sfXHbudbfnTr7r0XF0GwCVLL4MjbSU4g6xGc7nf+EPhMtuHUE83MSnpS0z2PYq8vOXlumjbxT/m+bbc8qLimiLqjHlhAWWVHbwTg4rga28FxfqUDkmkilFQ129oZbn4ZI5cOa6Sne1fYYMYHN0xZOkZgv13ixl5FF0GGaKo463UUOYJQahgEoe+re8pPpIhKqA5/eXm6l4qcaVVSYYqvKszZc0qHbtzkE4QK1MsNSurOEoq4s6zjaPs1kCj35/oirQn4yQeDowTp3GZCqtoOAkwpJgYiX9IYrG9AxNc1nhSyV8PsXd4MfXDkooQyl9UtuZsQNTl1c65oFAcHMekmq2To3zr1BD+n7/7IbeeumV9OHfN0HrVdPRIHAA2uRTzqvpb0tMoKrnsbcDIir36EGDSCWgsgIKryWFn9MhRcn3CfQg2k3LBzIKfFu6UuMaF/3lR/UkUVeHPWcNb17bcOqoFaR6ElSC6322En05JWWosDL6SHSj/Z+daLp1948M/sHesjwI6aQJIfsa8btIW1EnxO2m38sSDPG9MY3YViXQFpksdomK0o/WFKaBG+EI257GAOEYVKM0cM4EDCISZiWLBCQuDRRCPnxoGmo/4TOkV4gdijcrIHruwiMPsd5UgBkOw8xXUpXkeuqcUJlc6Rsyrxk63cJGvK2ykesUXuXg3IwR5NhdKVVgz+hySddgBTw56SeeZGApDz/KY0H+AOLuBufXuerDRUWq2sIUu6at5uLboLCgJus4VqDY8rDZpeXkuEfaF9I5inpbovTpTA5T7WvI7AsM/al2ummF8zMOdRzd5YGPylQt+YjpbHyVyEy/9w3JoXz3e0Z23PIwRzpaY/eNmrPJySr9iyoObLwDwQ29xN/3v2jPGqO8KcsL1W6ZqrHbKtvOk79T8VcVdKL4zOvWsSjGc2vDySZ1sjIVbY8ywj4IyBnqK/2Kz5D26WIWt4Sp7d0hqR40AX2QiCcv8L/Ylhl/JdjlvS9SnRqOe8JDsVEzuakR8YYSgM8CzZX/mIbAG6Yk9M+nD9diBVDHBngXjm9OwTLY/pWrWFOVT7/INwbftM7t5yQDC/KYxKcGSlefMgBwPda6HRMNPVryHJ2Bew04on7Uux05eG+/V+Wh0el2Vi8a4gnxFWfFroHQ6OIIaWBE7lS/ZrpRnstFXvuDL4Qh0O9fz0ltovmnWd2UL8cY5IOOapcFy8g21HC6Mv6n6rg2881xp9Np5mw36/YOuBAdbwpxyA2l67lKBqbficgMuVr1ba5XbCy6290pZF1K9pnhv151f1Iwt3GPcokPgdPBWLGxu10m2E6/AnRlWZtvmpvwTwNQa8tXUbmlQb6aj4fR37fYMakr2pRgvFQlpmNNbCQJlqv0Y7eGhtNs+DlMRY/YJLWIhMOeVIvAMvK2uBE25fSvc9IUrTdxtsjevQ4RR5AlwKefLeRxIlF8dGTVHSj9wmZno0BSmuoA8DWdE76GsdzfzNvRkbtMMR9BuUozqtmuNCxXzsZ/70Zu5LUbfA+SsqaWkE59WFROdJXhaSftuGh/TxXf7ZTIs/rw+IiPQUidmb1zI1flndUj5Ou8Y+VA+Gt9yUOuPZekvbnFs0lebk1tl6qWp814v+PHeuuXNTwrCvBzkSfzYdWAthK0PGR4yeaH+//uEi6wel/PiKKldmRR2LZnwCJOetSkb6PxzvO9ZB1xeHkWkJSPfupMfitruUeJLt/la70EZnbeEoddGflaQFVzca757LM05YCAAwmntB/ZSry57SsKAi2GukTqf5lGqxo6DBq+uhlB4g8vbxLziqWFWO85aWE50cIcsnke55ROJ65lB7MELiBfHYRCLkxEFj5rfHABXg4DnFnH6IZxrZVeUeQu/Mp8a5UMsFe2SMhO5zzaw1PTw1hppdrjHnqoz0UsSQSr6GXcBoqkTVP1p6LZf6JJ7ACN6eZ3XWudEMfSQuMcdytmcGkh5OHq3SzBJiMtSgu5kM4THSUNq3i39J8vMq4U4NQNbJ7lI+5QO9S7MxZA6D0NzFwLRTMqO5sGOvWoevWitBogW3G/+MHASLtGx+87jhFzp4p7UgXDEghSkGKVFWkg80+Iya7XI2TJRhl6fOGbQKIdqBKlQaZVCzsVbOBi1eTc0JkEPYAQApx016dGEgfMWJvxArxPa9yTcqFAUu6/VMQZrv4fUeaf/ODX1POxMYG8FqnJU4CBEF+3X7e2A0HwOONQiH8LGkvIgcvi9Q6i4d7QmCUQQvUpX3B9lhm85Lw3qQyCTvq0Ou1DaU+dtDzlJYdsB8sV+Xh6VjRMI1qn+MztO2ujjbfwvk+m85qX8+i4YOr1YA317dTijHlvoLh7fuJ+0vWOWe/+1SqUP5xOP/QfY8XsG22fNrzZ7jG2DNSvEtzYoF345KuTrtDWZYmfaSLDp2OnRzgFJJ5J9QjKYF1AWPwyXcYGRQ12Cu4rCxRsvdExIGyx/81FIePV39vsCw4dNBZQcEbV+zP7x4vSgnt55goaEH5TU+mYX7VMemAxllnVM+qyvk2HMlJXCmmFCIAnm1X1iNnpI3LpxyNbhqpywJA+dzLgL0OlSaXljrr96bEqs3Uth6saaytBkeE0egBrMD02ENH6SjDavsefdwh2SxBKd6OpDaEVXkgR9LI6ODh5THqwDhhph7UCzuGrhRE05M6mgTMqNLP3aFP8Wsn+7hpEinDyHj22/QXmXz0jCT5Hvga3OvSnxWi57I1r2tw+CEVKbVFbASllqeFEkMdZ/YoA+NAAeFeKl7Ybq5KtZVZocB1TnWahFZyt3+Zwt95DNEWW91SecX+/QZKyXU8icnqFff/O67EP28P9pJIMkb6nApFuYrTUkZ5v1OVIZaQjnPCW0zvpNfiJ9hyQXz413/8kArL1cJlvIR8/NoiU3WLhUYr58dOLVp6CLrxVOCHQmVYcwFKkB1SBUwbPyAQRHDS6/PPl26W7yeLJzEN3ihRMF42gz41F/ooFugZWwIKd2+lXQHBGQxFCHNLhpgk4pBkXdx1d7HygXLSux7861dsNAu44z1MfSZzYjhVFfZS2/QFj/Y6WCaCKeZLuVYmHeZDa9lsErXZVEtwjQ9ZwlDiS9wyzdNl2hC7wTcQIonG/X8h6z8BcnR1r2Uww62nkJcGc70ZFC6451g3clEMeEwbMa+YLiAmiuHwqI2NsSzuZVT2QRyJK7JvZ3BIbDIbDUq1g9Or6r6jEPzoz4O2eicIpZidyO7f8SEYcvEZkMiO12NwDeJ7bMMiCrY33ckjlZEu824BPlfetaB39gujeJ2JGGkoesmGFd6c0DLlFjd1PDwtE9ZeO7rIdJVWtzgHnGYCJzFxaKx0aWqUTxtW8qCra0DXA2jpi/p8EtRvbqmQ/ZExVCfo0DI4j1WsHuKDHedJwLSxFBoll15KyeSwWY0Am8eFW+335vNdU4miZgFPndeDlhwfAyNtic5W/XmJYousYB+dXHVtgnDjoEouBNpYYmjEfxJoSu2b2PpD7/0kkaeZtEWEcWy8kso8D5K6tF9vRcG68YOJg+XgXvW5sln1quViTUdiTQUnAYFwXVJD/VK/F8HhF2IXVhYtQYIZFgvAT6jXu6TqnS1Xqeh3l+ZcGrJVAVaVOeokHLyi+Hp9XfXoXGW6gTzBZ8mYt1dL9e8XN4FpFlOXYOXJGy0B641i0BM2WofD0Qns1zvBc+XcNWx3E4EyarpdotmFtbep4R/WkRUIl7i0HaYiqGnpnq831CnvZLZ57YtilH6bzinjZS39a49PZUDuuwzMF3V0wUCTv1XOn7p/oA3xV8rciFuop1JdOIXlZh2UyNNQteW2tupWyAW9JA5wtnlTRbivCfu26UjBX99ixCLI1F+RxBO16wY/ERNp1WtvRsk++PXvjVK93IEKU472VFmDFSpbBtNSu0aqWhqzqZKPhfgyOD6P00M64/kZjkozMnOpe/WfXexuHw7teI8D2P0nMvZpNn0O9s76enL7JnGb2DsLBxoe0fnugNAMF1/y55lfDToL6UPsriq19dKkyUQUXv/Snz+B7z5ULQ9XRcdu3CKNU9a/Wnlw7JBCjrK8UWV3Z0/2HpS+NjSSsSF2iaq/aFkL8wxfFmjXdz458wjtjPs2mNhx9DzERhuXljBFYcusrLK5818XQsE7tYHQmMtG/Z0Gzov0ZdVhPWcvObRdWOlNQ4BZT394xtqDmTMP4rEhCwocjhOqL733a9Z9nRJYdvFuAZh2MZpQ739CZSM7pBPsrNG+0nCpf7pv3FXjVIy/AJLklo8kbaol37o+g6IBz52AwuNUOnbPLAx9izuhnPSrGOSQT6ENR7B5+XC/CmHWqwkg0htcJ1M9U9lACcaFOYF4gQWIz+TWD02ljJ6Ic7xSxXp4Dtf3pZiaskpeFXCCaFeaaKuyo3l6yA5aZFtTA9TIQ9hLprTbuOaDjStxj7ypaJCzW74WZElTFWc0joepniTrEpbhuWDazKmxG8NmSxDM/N1NuxC75Zudzwa0jjYHO5h952J7TNaIEmucmAX62x/ADTjbVrd+JuOpg1USkFpQ/mCKNz0bZm3zH4RTU7pWNWmBj/oMv5812vltxQcZqkd40vIa/+FxIkvUFd7EPDgk7yfInxjqvUUJFynUjOxh/pHqd/Prxyqb1tJnPMAU4HlbLIodHCrzzlmynhVLr2HmlGGUAE/b+JaQW1b51iHDg2q1y+d8cEFBffjKaXgIW62STBhgMDD0LIyV4jYvEp2yInUHnS+LRC8A23Rn5NHcUh3gBBdFsYux+culpzJV1iVhw3l5iMXc1fq239xz+USgRgHlnNo7rLzTy/daeEnm893A2/ZSe1j/CqSKjN+wV1K8f3wt2oNEc9p+fF5KFztjChMlqWx6QvbjVFpZqM7h0z5pwaJoN/AnsbMucVWWQ7G/FGynKbWvHxeQhDFi/Bn0b9RqrjIzFj1XTzj3fKH+jSLrVrmJxY//gtNGkYZnUjGPzhiqbWC3HxMMSOYaRYTFG97MrNHIT4vuiTmb0m4dU1/AH2i0xSz3h71Fipf4RlRBtgqecVUR0JD24Sz9B7PnMsnL7FP8QgKaU/tGXAQ0TK3UY7qd7V/vXv+TqtMmMHbDoPSK8IeiLtYRQQHdVS7nA7UGi4yA6eGQF4pRzz/FhPFldfkp18cDFHs9BizDXoEuAipKm728gotPx4DpPhSW57GTuiVJL1JHQ9sHxbiUIIbZB405m8sWEwZsR8euDMR60d9yMeOPl48iijqcjEO2vR98jPLOKV/iQQbypCmDwJp7IUV/TipjyYPVRzZ1xE7HSvqJN+4KKCReWSs1S8QMUtX5CU+6HMz7QnIWzY4w9kE1s+Lb6PJMKEh8aGeIWoWrgQGvY1MKmwz+eGuc0NC8T2afn4XZf2ipMgT3r81rQd3yYimTbMpR+nMYScXYPVD0kklHpcRDS9TGGMYFhYaqixP/0jFOw1nNe5TrxbBTGdoyCOZRlf0Fdg6yGWOYucB/Vw9knojYc+bGykmz4+y2VI7ezUH5oIFdUk5pJ6Qqwbk/5uxw1wcbqGMS+1K6fTPkqm6NrQes7Wy7BcYMlJpP+Q/i5nGNS/4bw5/1n48G/aKQuiVOHchaF8JXZdsGmL/250L6pzoGwfbtXfc0tvKdAZn5WcbG7oM98n9Zqx/u2vTCS15tQlQqIUCNsoF2KHAPcdXkzDo6inKkO8LhN7IWfdLYAidn7aFh6Y/CNhVpoNFJcJiC8ima1IfYOzDbHGjqw3QX+KJrRFyC0ujKhbIYJkRHtznG6wdbWR6oN2RWHBzjWdTuJEKyKSAPF4iRttWxr3JKzh3WK7Jme+8cC1srqXGpqrupOO0pAjiwgIxbxDv2STGsJ5Ctemss9jhF0V7wwpTbbZkvqiqnk7TKQPRNgHVZgAgla9IP3JbCf8iz1vRUI8Y2pyRtvmcB0mfNg5m5osy+RZKZ+XJp0Ti9zH6uTFTHUzjNxRcXRArRD2C3W7F9D7XK29JqBxFc9iHkjO/IKlV5Sm5gz6EfwQpuhEmfgEFi5HSmcIf3XYTNCrJjlEzEeMhyPyDlmG2PG+6l8iLDDsUvJRKBwiZAFsuKW/2oRyRunl8IJjp29iukmj1HU/CQObEHQugsbX8HpOsBF/Ba2vm5+nbfJCWJCcCo81sDzhVp6wwPQ8QYAPttXHDSv/JGC/GrUcCouEsdfFc1nl4XDdTtkhQl3/TTbuNQs79S+WN128R1/Z+VQN5kG3NI7Yp1r9rLXW9Ct2HCh7ofgq7i+ns9XvLHWpf/C1cr9lb1VdZk4idtlDUAr9Fjbt43r6+Tt8M70k4FyRNyXutCweXeEqcciKxUTj/RfxZRa9lQ/O65KdfLUgtEq8FZfsRgfAVfwqiits3THfh3l/KQlU40OkA2YwyjB1HQynKRnRbXQ9xGzmqyQEdUWTuH6smnLv2oRvlUEL6IqUkMG/Xd18Ke105Sv0MqyqX3D1xM3SW/+NUOvkqnm5twRciqSQWqckVlxPREb+vCDDZm2wzAPxZbElgKlbFHV0WcrokTrFYKfBvWsaifY8pD+XwG5eosl+2Spbha4YGgoiJgqaW9IOmWqxrRg4E220Snd6hSzx9L9lTHdnPDUB+wWe4Xc+wBC1YgImYXVIcBPd0Q0MqQOltU40Y3iqqAiGYIGGlS+Ln8cRy5zf3aotiKUEOB1tz2kQTIM2aRwQzqFqZNraP8w56xgdpYrlZx/XCrXGeuv5Fo3UYZ63SIvd6uU81ade+bR849Brf4iAuQYM0z7EdIJeeXD281j2NpX5EZq11vlDwQBzGK+Cy1vje/+0L8hKEK2rWyP7muorhIvI7sKJIjqpiEPd//t0c09BEjvuGw4bogt/TV9SFaRpkSdk6HHHDjaYv+LAkHHQWD2NXy2snh0KR/tHFqBf0UIDcHFkW83rLyaC9JQOoQQT5m6lQ5roiZC6M69rOQ7ESChuPKx9MyZsuYN3rteQUNJc2zRYA1t8zKaC79x1288kLcUOtlrR7Ym16IWjZeyzpiLm7hDYOIE2K93X+/P8a/e8Plfi+WIDLP+TZGXFrDKBDxhr3DdAkTUpVZKIHIz3kdnPGLwdwJSemYI00eW8Gg4nsh//mBestFlfuhz/0b5Sp6JFfWB5YE7Ew0gvbhRyDKX1GYCb0zyPhefYyyifRYRnpTYKxjXxQgymT2z0wQ/YgiG8sts6rRKW1eDeh9ngWKkLEqVjdeAZzx/Ecy4FrSF3qv50eLzoCLxZ9uHqprW1dekJYWX5WbGXOMErxw2pGR8RVx2c6KvkiJtN4GM/xU8c25rUu91fWbNKNfP0SmLRraopYMiszP1IMX4sFdTsymZj3Itak7mzlq28pb6Yct8r/KihVk2ZRJTpObgoxTds0vlMjFqEO+Ha721DyMRfQWNgN5CkjiqHqmwlHM08X+lUqp7gwv1MsZ3K1PwSP3Ppi1g9EI4VTfMP9bPnP2iT5dcNR6jYvGVDbIL2gcC+6Y09B4mq0Mfbjw985TGO/uYSv9HomTINOa1Fx41/yo6E0i7rKPCjrzSxQYVTq1+cqRk3r0IZTLNvIHgtgZRx26dsvYLxeJcevxsNge54PEOWmxyHEL9SFnbcgOJ68UJ8Ix7For7DEQ/uNo0jjFtAwpMjr9IZLbXShYVsRXUEr/4q3KzlIbYasHcyzpk9xhVrZE0PrFwwC6YwENHfe44Ty09hXjOSY9cc4NFungRBAFxQ5Trdb+/f7bntjA5pkIGD9EealTZFusEEuiCw4Btjf6J4gjnKwSA5nH3hYEHuo1frdFfnBlqbJp1Bif1B1SjKqQL6b/4bU97my2PE2ltS7gfCVAB4ahPr9OGcSI+vkpKnZcJU1nUExJkpdquan2WA9W2NT5BmVGyvyM7nbWcmOt4vc1AMgZdjcpKIiwRdInACo+hIYBeo7XX3mg3q6wQTZhIhhdpZXkASvBt4QDH3fphgA3ax7jsFuXRTRPAmhLwswmutRRiG7Uyb4L5uyS5B2D2OlqZXEJ/x8GATF/CZxTdXd3fevrYND1cvTUHeRfWi3k0q9b+YXKdZlEo16l7L1qFqQqjfMW9QDPssse9QnlBooZxYyCuT/XBhb/vHhx23WrrsJqvTRa3z8OZeHGk9da7tqTm1fmxN1OmMFqYIZY+/MWUn0GCWjvDLhVma0qi8wkITyw5ksynwHNZNXj0ngCogWKInjAUh+3Zx5VoDFw9gnntD0vWd+FexUd1dTS1kNUCFYk3iPGstAbLR3R2Vdmkk6YYDeveH31/9D9VRRMFr9WumTplo5Cm0xlNKbRXQfjOB3Lwowy87zIOcXEAuF3DatxpxsugOFn8peDdwqIvuL04oTCrIH+VzqLWvjCzSnz61HGd5aQUjexJUdKZ+nW/TUzOBk+Zodvc+hY92f/vEQFrOJ3JcdxJoZX94qpQ88QSdBxHIlIPFogG3tBqDprZnRsp7h/gGedRGubUp9d1pusJWbEgQC2xzQ9u7UZf/5Z7XQrEl6xGCPk8Aa3JSfEOwLoNgh5pD2/O3RLxlQD4m+7LwhWdZq+g0d0UGW737m58a8oy1P5TRI9Enikue0aFR5KoohGdNaQBNgo2A3/ahURWgFF7GIFryjZZTA2pF97BaoRKXnpZp2OSCqyVJn0cxUNYnOzUmVZA7ZZTe6RSho7BpbH6tjiluP80visPiVPsJjcirk+BM+b2/T2bkKM6LjZcnjKiHZPwoK+YnA12wxktjduu9Ko6gANjKTBSiZIZ5rkZ5rxOZuPigZ+OwKj/aeqQZU6fOEPNcH+2UBanAVpvyypWoKvUKEjKS6F3wOq8NXXWes+qddvXWPdIPkS+wYMW2MCTFyEuWdbo+1xSLg4fzUxlGnuNmObZGIlI9rtAzA+Eg+W9Vj8sm2jBd79Xu7uJU+eqssZWvS7Q0/GSmnrYG9Sl65u+PE8t00KtSy37D+lbJvc9rP/I+J4a5eea4Ijqrw9yuXk/jwfAiBRpvEa1YFdYRRhW21JQ8MgWpjy46CIxeMxPgWOgvEZyR77gTaEXVyaoJYxBmYvWdyJWIyRTFVrHkoSpMRimFV9Efh0jG/n0Sv11YrvhRno+Gez9tdhGKRgspFIZjIlIyCWzmcUmH3o5ozLDMvb4w+GwPhzG/7MEAZT1xYwv5EM1sinkbOdrdjxd+A3Ek1+xkVYMExplIK3JjBhb3IDkQVPc0mMQyJ8WLf/SjJ4u6DJb7ERKMyURXsYRkyT3Htpg3eiSVFyoryhaIROiaJiHD1lusdGdL9kXV8TBSm/Z7OjE1++mIJrBH1GqHPuOFnA4irz5JNJjAziO6f4FSaKnAqMsx7/aDSjQ1a/+Uxd+Q7Tpzhj72JXSgX5LuR+l1qQaRgXQuExcLR/uKcEAfqYvEIKR+eD8jWYrEapNyur/tzil5k+lW1oa9ks3rXkEGZGuNYONvv6GLUwPFIDII2UC81mWwe4Rbj8vRB5ade/zYQ6lJHpGG5gqhdj5qkN06SwTHF2TXovZloF1GZQ8KcwnmQj5wuJi1Ebl+hru61DS8SkgDzwmaiblPvYKgASWXSEJMRsSxNWDFWGOFTBDFAfuaoRou0UO++wg5IlGUFu3/M6nXQrF8c8jjX0+9UVsT3lKr7/UVGVllBJgVKn5ByXdkSoRXC0PiydzNBfMtaCVGzdOWnDGi7GKX0a5yiOFQroEsgykix3S8syX2PQvTGoKWp38ImaYklchBuOSZXnv1ALwkhz3Hi3dMNYCUuRbxM7AJ1A32CWObW4uwhuRlujfe0Uk++drbn4GxmGRNNFwEk53HqbBlXUGo2lekw0SNgGj6i3i8iqWAu0NRH+boaZw9C+m1HZZ90nC9WJZswzmLGtOlJ/haS+1rFEunKfPXCgQPVJfPV80do5CkpZ0XUcs0DRsRlksaBBhKufidssp8r18+ksmJ/NuyQ8yoJmaiM1TdcHm/Yra/UU9s+RcQ6XPfvM8zw9mYHZrcSXnvyc2JdGH0e7xSzRZ06NlP38+jon6y5iEdEIlztw1Oky+SzDYLZ1QgRPW+tf0DG8R5ueWFSs9NIzNkz1yxVCqibHHD1IVFXuh2uryV9iYkr4/yv2Xc7+F1ULn1LqphZvu+IQGNUMfClUie8vmHz9I00DRO6j74rHCeTsKeB5n9vUgEGGGF2HKq4awmLpOg67cDAqycPBURKNXV/6OluRXW8dPfI5yjuMhKK/omfbssrVFbPyUJ+Q76ksJJVN7eKhhig2lsursngFOFvPgXpZ3ii+nRpMWzVviCfRrYv0m2l/ZxRlBM7muPAYmEiHrJzC82ZO6iC8mwY65zXFdFNLTvhEKsprbDCoUrG5oGFeiiqEF7hZb3ukrA49fmKvfLYfFD8dn10LZdd6pIEGqo8RnXeOjXncg/XwwsHOJ7v1vHJqsBth3bqsiEAP3ZUAZKaOHUEuHqGknW5plCppneHl6eFaKMOFvZ2CUqvLcNuAceo/qyixncYgyZqph/WCVQRBvJ8BqZ/ol7u3DfiOZjFiUR2Y7buLRd1s67Bi413QchZJpSUyte278o88h5qgdWe7+YKdBoKtWSDB7C6dx9I/pa1yOaQB2nXOSAKQqe0vIP427t3rWIsG56J6hAgr9unBEp3Hn4VkXf0mWpiNKs9BuKi7imMwF3V/mkWEelXlAuPFroRyDuDf8LRNIxwQLaBOw3uHlNmVr5rCRFj0O9ft+/aT393XhSt4TMVXYF292XQvBwaytEjZ29/kwkTOe+1PlW9clFTwfRklrBN7uMrF6U2FvH5qc/7B/UwevSb7mRUDoWrRtU2rphwSetuX3kW4cqE7W5oeeWHvW5jtf3Dt0rcU0s2UDwPHEbWhVOZ/hYYbitjJsv7QsEEDhlaB43ABctfKFVK1Bf4HqYBO0BLkjBlNrZCFZ2W+y969XoF6+hJrYW277jCFoo9F18myXmFLX6GmaZQxHSPw1T10yIzOCU53LwoyPB82bEjCMQ5TGO9OACKgJmrCIakg5JncaGCNZEjPzScz41ebl6wQH9FS+kLwptLzSVZW3isywqWFKUxUCwr8Wvd6pYD9jQI8/DdLwV6EoGukb/zoWyAaG0iBjGBVmvvU3KtcmvgzrYru9RKK3sBfn7pFpbLmZgOa5GI972e1Xfh08EUfGPedcQnnBgGXl8A95zwDdalWBlCGRiFNENofXRr+UMoopPrOk2+iYOM0ZCVgcEKgbOyi9HibUCd6BderyYduB546gQzzW2dlX0jq9tu6l3pyWpHZaXK6RKSx1Uls46gwK2FITqI8A8GerMW7/74jlA/pDivjSkvjgPwR8L/jbefBO/8NZ6OLcO0P3loiZZ1raL2hJuU3ofYkYW7HkK8RkqUidyPdtK/EBvFjKa52q4KkZrBGjhE5MppfazLOyr4ukuGgrb2BivJePvyH1vhG2EXJjoUkhgr7SAtDZpEk9U2519M050RFkBa9x02XM/LcA3HdZPqqHuAqGyUvjs7xCpjezYVwc7O1EKGgGAQzvMlZ2j1HT89BueBEkU31XuieVwX92rKD9LeTmmlj+9mYJXKH4xg6XQdmTzWtP9u2K/H5cYrDlp8TaRc1i83iCoMz9+NzVkxaWyEYpa3KPcMTelTxr9wZ3rW5+t1anjOfMN6yQL2BoLvjTCHfWTm+eo5CxbwpXpRAL9BiE9xgKRmTTMPU2Fqv/VwiDLPD/5yYRUNgAek4K7G4iMryTdLliN5lH//QKt2KsxDbKJRj8H7FQOSeXJr9IyhbxKfOLFsQe5Gb9AmQWlkYjHN1MAQCSz3COrzCvlnOURoUeuYr+fra/slbvr/99Bl0VKb56RELkBeWDwneq/KxUxgAE40Xf3Dd3M7OWUuLX5F6RkSKWvi+T/bomuAKCnU0yU3PSskn2n1XLB+K9paHQm1uMn1o0aZx8sXCiywcAvanR5NiXpgt8RhhApFld8MEMjKLzSUotKYOGTeEJE1T5bMXstdBpk7k60sUmZ4Ar8MCj6t+7Ux+NDvKbc1hcs8zqG7IdWqA80h3NXm2pft1Zqspy736BchvBLfMGkGDt9hdcLrczZ6lDzmARFiJK/WH9T/B6uoR9EOLe/28YurE3v2KDAxTIQ+43E9upLRSP1SNFHevZR31gjL6unQ5xb8MSmcRBtcyoSRh27hOtZMQWyJwAr44jcwbEaBi8CAS/6zxWIKFoU5tHc+q2DqxbDdS7+X8tzVo0Vja2O92F+jYgVv4Jr1Z7zyuWYLRPsT7/ojiasej3YkadgFjLQlETuThILNAaJN3kfVWaYeQ07TFtVM1ptk9sgK5XprqSqGJ7czlNyWZ+OTCwh83dFzBcHcxnNM57U9lL8p982oJqWOd1v4bOZ+tCauSnD+ekKRa9Vy62jhnZ0S+7WUM4hRjjNDOK0mI78QfBNeuIZkE3qm9855Oy37KHajB+dfds5BMaxZWBiOEYyBoaf7b5Xk4GHj65zy8+VqVSY11YBOTxY7K5dXQWa8NYIKUAHZa0ZgUIE6JO/kgYM5VDlevTqZ99y8cSEqZDR7obzMgfjHjErj89xpgzsAWbNMAUSdfUdPeFtTZKpv/IEimrPBj7HbRJRo0TThkVKE0fYMFt01DXj1gBY2VpUL1DlBIhwkqeMQjb/ZKuA1PTvQNdzXE3NrQpowwT3M6YWKZLZs5Qx07UgEmMdn+Zmt/hdtHNQ/mLeVe+2t9nq7viI2JBWosdQUVFgRm4mSIV3vhYFVvnPZEkm/LRsbLC8Lznv0qFe/7WPLSqw0DrXAM2OtIn5XsVGWFnpewnx0gS9QKLoSQsfflLgcBKWCBkMr6BC3yEYA0ol7yQflw2IwX07t7sGAlXqAGeuS5hK75zF8VlkcOlLSduvxeSX/BYc0azEhdGV1NUO8e7lYZvqbBaMVNqHSvE+aFMZTXTYWbh6/dGFGvIaZtzo3kCSlhTEOuP+SJXg+g6ok2X9eos2DTzv+VI1EpliqEv3mfBND6TL7/ZP74dovbwJmc8XxVtL3EssAxHb1GBB/JYE/gcP9+37OP21Obq2yWK6Xh/UQoNqTMtISDxm7e2Wm1js3F0uEf1h7NFwEH5KsJPWlXbw+zTQaNG43LT7ELliuFiImHExGF3sRWO9ORAeZfnjopCa8rqC1GV4Yb/GXY0eZnpLkWZFda3trKwKMBdSElRaL5X/6oJk2H4T/KGqOX/fz23OvimqBtNlY1XbT3gWR7XjgUHdpY04cdEe1Rq0Nj1IRemiLcZlPG6KbHSA0sqDulPisKg0tqvnalEAJhenMRino4ljqXhjn4hnOJInmEfcmlNY2Vagb6gBvg/JgoFBam7/iyFK6C0/qF/0LuqWk/0kKluiYGCRO3YhudujGGuQQIMnhcmqWvUe35c1uV/pchnZRztJ9mB98VrVHHDocL7t78DJk/3ra3/nwHqRXiwoB9812owd1U1aTofZtgqd4yoSU6RwPbXHMxmgtoChesCkVYV8m1iSd7Dh7tkt1YpwOXWi9euVuNq/EEue0T3/U5atUNvKeeaLjwisVJPGYoxkBGI8M9JyRyitFke3sgC3fSwPBenZWapvG0M4zxDLuSXr15NJhg1+NY+NxFSVCRbH9pyGjBFMImt4sbHX9o/GbUPyAPfK8qgxh8zy8i+KuEzvvYgZaeELl+4QrHQOhvHeTkbMu0Ta4eNbJ6kqjJyE7FndAMdD595Vj7xZdZsUrVTrr7gRk7+Uo/jCf/pcYq8dlH623hvAU5sO6ZKf+2L5S0r+JO64CLyC1L11e2+OHihCDWmBZArFwFw1JuJQeaPanrH0jl1RrbWvAPh8DBdLa0b9uniKUFcz/ttE1S3Mz0ASH4Uth9IPSxJa3OMMtBiE/taV4LfK261DgVOd/Pc4ZthfnUJCHFjDHJh+rdSN2niTka7p2awlT930D8gUlHf1PtC9I90l0bdKXNYWG47WwJ1EvCobvNLBv7NQI5/DOcusf+RQcTIA29Zd35niFmCAMG2AxqZx+pdJVNLgmH0xwiMY3mtFSojn2CN1I+usQJrbX5BP2Iri0VFeF58OTv0XhXbt7yjKj+7rkJoT1c6LOC/eZODDLsK4r079x6kFlObmoNBhR3bEzvY/iTxJ7mf/+EvMVzUew6OeM31ntQcuwEHRQpLJv2pdkNkqZFm9fXP7ljX67EngTH0bvCUk4jkZ7kJp3/mdh0r+hfSRpCIr7mk/eYmc2mXjRleSEBptzhx+581pwfkCFpcQTS8UoPfvUuPQ9o2cICkhQV4Emjdc9JDnfzDyfj6BJROGUdgJ20Kc4aF/ew+TJaM6KqzUDtuw7Zu1IO2oFvF0GEdJ30YCKx3KDSyX5Bzouxumf64ltjwEWGYH9EetAXVKxduTKKidvmyubBTThLcrlXUNNHxaiVq0E8rA0OILrSk4ZDTLBPH1Z/tSHWWySIQ6ldu3NfSa8BymBOWVCi5Qqn6r35vFxmnTNxM3jguj8FmoU1Xb+0Dk6QGI269mmdXXSLKDo/+d1+75tgPeFIyZwodFQv7DjoeIDKMYavCjLiDMbAhGDqXXznaEux7Zgvv5Dn1ATuYdzLlaUBDOGDzzl2Y2DBRq2Hutegwk8he6RJtxLQ29aZIud9C4gOl+mMbZHZmaSCYvipuEWXrgqjbgQ3J5dTU1aC4SHii4aJQU+wD0mhlCMP877dmBuSFoWFBkPykz+wGUA5C8zzRNH31uFHSnW6TJ0tNrRlbKMKp0uWUeiGBBmVmImnPAKJS0DxQK6NvXRAILEPFVhwyxzGv3+xXCDCWjtqoM/4gf76AdhUkTBwR6EyYJe2Hq/zE8PBSPHNrkYT/ae9AONYgkyXozflJdWCWFIdlaUQ48YUB6odsus2jL1iQ2GGgKcTUwqke5HIM0DOrc3MNXm2vg8QkY3/gxNulj23KiLhOBbXgUv8R4i4uLPTwiGBxcujE1Pr5wAyGLYzEJbwe1s++MaAkfMo7SjO0rrDVueVIb5KkFTOIx6J/x+MhFf+x8pGKy9skyML8nqGYD0HLrg4Ht1UxSQkdsfSjKvVAbKbhzw40NxWdBpEduqrfJG408JXzLU78mzm5M/ssmaIjo6+3Qfv87QDf31fxtrdmB7vQUZqoNVe2gZ6LkHmXEvVT1ayRItQf4oN076qisetuXOh8mzW5guuz3h2DuEfo1Vn2IEHRmrkOYEgHAth+yZr+C/ZK2aVygvwK1BYWMrQyWx6i6HhhhvR1bE3hOg4nLfKaZQiVoXA4fhVGwKHplZ8poHkh3slXYazOGNmkqQOn74b3T+s+FcmNlhc2RKB5Z3eC9ZQBVr2XuESzpHx540uCSUTwTSG5YD0K0EnQtQIkGNuegR3Ve5sDKzXuobGv/PBYlvLsdlD7EteU93CojqgX8ffukDoM8jCxT89KUmkKq9gdwweGzi9IJUahXVaV1KXI1AgA7ASkekoR52qnHgZS9HjyCdlz6Bj3aVtlBldYpQtPtUrKu30nBqARv7A79EQmmT1VEEuyq/ino0xVKkoaA9f8WBky3RbInbBFvl66b55/hHecOxX8jVAYJT00BTJgUeqqaa2cw2M6dCdABls91LhY5kQE72n/ZeSD0cm4jo1ED6/kA7wn1Epdr/BXYSweCBqUYnyAtdx5gURJRBz0qJIIKvoNN9PSNaet4Q7xBnl341Dta96v8wzAzZ4y9eawGZksVSyWYfLbMo4CNvyGvyDtfFCEGRtyaA8rSzMs9qG/JNjk65D9uMquPFNmga9pPeO18y4yATm6G1oJ3B/VKPsMjecGGuDjLN2ELSoX3S9pjUMZPCje0re0/mFSRABuLpWKzk+ouOf8n7dzAxQLBD7zfAKATI+gjYWzK3ELbyDwOuTJp/kzTmReOMDdBGBATv8FKhckSmjM+H9B7DJK+bsg+CowL+PEaJFbEwtbHMR/nkxBM/dbYJQMOBd3wiGvgweC8LCXG/dpH9x33oiupVDUcr57GA3rwoZ4UIov+FX8hThyWfP/1dxy85igigwbMS4j9MpCLfx7GeAiZYTkiNqbdvU0W2CgOeEWKSvQhlT1BbSDeGRl6ebzrT1jYDuHysM28bzhzq1uiOogNj8d7Aum6tZopHsgr2de98IqEyc6HXegvEugc4t6c3qkkXbIBveyNv5OIhMezHH007WN1knAL7x3mgwQLSnrGiI9/71EPKMszqesnVvpQ8YZV2nGU2FLnZ81enSGrIMk5gdvTdtAd95zrwv9kcfp4nAnf9kUZhWMGKy0AI9eLrCNmKcVe0cQKWEgIwTfDGmadVhVNH0Ya22jOrc0rGH+wOI7TkLvyozYDQ6zCeDpfzxrXs6++F3mDvDsx1xMn346MMIdiLnFtu7t0Fs89kXV96cemBRpPHKqbffAGxrrCCbRYsf3V4sSBoCWSKmOJBK83bMW2CqE8Juk5gyZ3xXZIKE0NQ6anbpM+YbPhPEw5uSde7/L4TxWTMmeNJCMO1FCzmT3l7OySqebbW8GWOMClQCrsS9lXgXFs0s0MIYHuCJoKlV8TZ0CUlPqSFIrQXd2m1KfSBHnyfZFxWUUgRq3GUw6Zb+zLUqTWCpDxMmvksj1j26+2xn+xuk/RbOv2ZkDP5mimoCA4cyf6KLjbabAE9cIo8FHWbQ1vl6TTvukNVe5Lcrvjhuzlihbqyo7doZ0DYfTppJvLZLsX38z8j788L34DrodaBmFv/i2dH442PQM7nmsH6+d7WU0n4DjsKOmSng1zyZij82iUiL9xFbFzpLVzkHVzLgu0UORUfFX6tVR6qT5FN9xLzXbD6nMgHwx3138KkQutGj8ZxaYkWLMxAkhYlbkjHrjf9dsOwiGQ0FMby9rhFHc6brWD9TK+fomrZqFOMGu2yu0ds3GpaHGd3RzDpUkjb6XVOv40V0LgpPWzuSM3ScxjwOfisSGwjxVMh2dq74H92wCxkSXN7Bwo9/HhvVPHz16sk44U/EF2ftRj/WOI9UtiCkqGwyHCkhFtnnnTa1LSgC6Xqhu3OhdpvATPOg0HXo1dIL+L+QfZlSsBA8Z9sEBJf14Z47GqLbXPaSbrG2O5j9JgG9vjG0qTviJxR2SID7MS9Y8mCAAOR3mlDM+wHIIwcMqmzgytXUt5Nd3D3CSmGg0AIiIE5kAV7Ybm1wd9wFhRALRIQp0wF0spcswCOdsvJVhbl6fs98rubmw8IQk4Fgoz8/NlppW9fZQ7/ZiDuJHUruLUVckQ2ZbbBEaNwvKd+MgwHVRuMjwO218dfDchhGS3eQxqYFptQ9D7dqJLUuw7d9nrWqaNbA1xNlZvWonn2vBPtEzuwvwCs6wV1ogdZEl8thL3epsIop2rUWmJjoJE5o1m71HD3Hl4DiyQzUpBeqxFazdJZajQcvFFV24i0CBUtCyrI2sHNNsKaVVd8/ieS6ZCW0HgOR/WBcCKFHHPo2g8YdEfdpQZKJaW4w2bFAr9I8UDBTjNIPQ1KPEuUUvXOQ9/cnf7j3/HIoZaWQaH2zKiXVAzpiBgOW+HxnLSMdo/ttCqN4+JB15tZxfS8Ij7ROeOYi/YDHMPotADSutw44rNIOHpE8eCyMbduF5+opYkI4MIOqmf69r4BWE6alz/3pp8mOGl8PpJmc9une7UdMty8ZEca6+Mx2pJLZgEZe18GmMi/m324GZEg3tVes2izI+PekI7dEMiogenQj4Ewu6YMew8AQzE8HMi1L2eT/bnlDjwh6ySwZOU3zkA8OqEsWr4UYqWkSTXPlSHGoYbaJBi2foH7ILqx/HmpO/ZNWGdkvFGAxcmTF8Z8ctbQE3fhA9WsWEAxOnY1Ff2bSU6fqtymhaA0nb/SKx8WUbln+LZY649/u4e4kausqX/K/+G2cA/WelShebouxSzFp1tmXuyYT2awX7BcYuhfSIz1eEmfTxDLxeBmNzJwIKLUaup1xUCuSkXrDZG4NpvWoPdvu9KhF9ZQ080RBheioHkcLiVqAs8AKUblc+fWc5vrSa+wDZ5u5sFqaB7Ur4pIHM1hrdR3kRIJmkLqQox5acphu4WDFFFu6LSrFydVxLTwdniquOsx9STGgBgQXrryTEKUOI/PgEmvXWe7yyq3VZckfGOnc35i2d6NsSLZ5TIKk3M7x2B75Zpp8KVh6QvLS6IGFKmUGlYjlKG3bM+jKoZGvTagzWvS8vvEGdzgEfT6C3mvHRHoMldjSPcstsMUuymEL1nfOVEiXirySJsEt+QAOSmP5p4OQLtl9nev1uyok0tYtjfjdOzdRCWBji/QWelFFHrL6x37iHtRnAuR2e1d8AqrbYx7Qd1ZMll7+c/x889rXdxdaCzJYZEVrXk2RP5kqxy0kh601jS0f1TfxYkmlVwWohkhhY+6YUc+g2sCLTykVGGBH+dGgHew1XGuVi5WYJut6443bhKB41iLMzGo7T1USM0GuJ8YjszmOTzypUnCfZe9/MFqLHcMf6PH5MhYZltGTiqjmG9FbARAUngQklyKMdLsAS9/rGqa2g+1GX1isFUKzZQ8YQDqUZWlFQ1SP4Ws34BAlK6WJnu2yihYHFT8Zul5sIAw4N72xFhFkjBDKUGOaGyK35URgTIwnTFavZCLch34N4orCWGtyTxa3d62qC2WWeBln118UV9mB6mk/gBvt846eShqlt4uRgK+vLSTrABuBnvsvQOKRAAe8nzR2UOqBU8X/F8U8z9GrjzLeKnl3dCOG3b8bi4HkZpnCNFnOsXb8tSgMZUjc3obRsLuegB3yDZjSw2BJFCraXHdBo/yZdbhEN0nYw/riNF6v2bFc7Ojxhxpbqo7rHhEDxwChikSn8cZGwGEI0GIYILeK8eO6V3O2KrLJbYRx/ngJdiIFkb6Y12JOBOqbgQBlj6lvdm1I7tK3sQOuCKbR52W6ym7FQoyQnAZHQ0fal+I1ga7gbJ744BfMPAvgKhKpmk71w/dayArz9Vev6QLHhapAH9Ru6y7iOxLI6zYDv91bXsogdFqEmOxj1FWTgQ+RozOh0F0FmOmQqLmRqErt4VIGkLZx/4atk/yc6sP1J0bI3dHSKzht8OhGfiAC5eF0bJwIMgu5IDTTsd8lSBvX97FJ1kdj5IxO/FHOGzIa8iwPM/97cbjodyNmv4F7QJX5plkFFAI0bGUiWBdbj35MYyezHciu44tkhdFKRNVX5jQkblnOOwxcaNcLDxK1P9vNEJx3DTmC6a+kSzLYP97yzLiH5bdUTF/yJuP54CgIMxN2hVLjYmW579Yb9Lq59nOI1TqdAjqWIK3tpnhV1kFWVxIWVlNJF4/j67C0u+2oPjNUWjEzvkZjvUDLbecI6lKSzMEI1SgpDdhMuQzfqM9OQxU+sVIAFtZq9NcJL4Ih50lRVgpcEwTZJZKEmxc7anpJc4YjIDtoe8t4L9uiDZCQL5LPXsoZ5Ns5xhWDIrqxr/dSgay0KukTt5ly4s56xi8u98nXjx5izF0Z8iZiy42tz3vmfyIu/w7j/WZfU56qCpRhCYRiX8r6VUveUBH66CdKdIgU6mTJRiGnNg15d6pgfx5pntoJAn2gg4fhDmMbINJR+LM/qVf2XcSMJjECNQrUQiODNY6jtIZD2AITa8mWM3glrtQslfN666ymg0GtTkbr+dQQ8uZy4rBwl+YoOu3/3lQBWa1Glc5PxGNanwXIkaFVeD0nr4fklLsDCODwIO3TOiajKYGWymmzM/yG2fc0oQM9xGG6wWWCOvoeVKNcFE9/vC9FeTikyWRArG3Hb/sFFBYCPT3AVrYGl/eqp556PbZUX38GjUqp2u3V8aetD06cJPPz6VGRo+a3u4l6FTJ/k/uAjMfFc2d07Ryd9Qfeyg4C218J+/8qPPeVZilU9h0i+DBG2pw6PP5ZQoFXmmDgul62n7DujKwRkXsmmNSC9h8NR2nNCwfc2Zvhe+ZQfN5z3BjOkzIivK0KiuvG9ixF3b5NNlbno8j95dSr96Xxm9ujeKByBFUPUNDBvPnFDGEgjsr2YeD3Gk5RuYcU23/6yeyreMEbzgieC3veF5PzoY5ieibGSrs6VRqye6zCUXNMJOBC8QY82FsdcqDUUDaZTDVWYoiOyrDulWO6D4712DOcTG1el/qhewTADqlrwOqve0gP1lIeUA/8Kc4md8iBfCCR0aEq8TN/LsNxIjBmu6+1MrYkUtAPwlP2LXfVFXpdl8O0s4pmMcYykN3RhPGypyLA4jWJXp1G9HSxMXEkW4sFGb6O9Hd2+zs+Xn4+WJmM+wzNDDYGDMOYJH8l0+bw8p09ptly6mlZabHIlvuKehrQA77fnNCo8sXuUy5DcoJi4MK1uKraxQjuv2mc0GBF/dBLv+yiv9tEh0y+5QlsfPToNeO3dUkJ8nszDBHai2o0Spf6P/JgE2kq8Jmkq/GRnKvLDJLts2nhpJx4tQexZkfF+a8MYAmEqiTFaPblF7uqdlRC2+IOIf5LRmnfdbHfwC24+OdhSJtQksy3QoTehu0oZu5K61E6qQt38l20xx5j4exv3S2MWmAMsRTIFXdegkttg7yx4uQvL0wdr2WmIEmevf0KkH3Y7zQu5EmmkO+qb0Zbb5JVSHxCWIyRQ6P9Ez0rO7BW0QXk7dcOdydlgiduqIdUqVLUblXw8wDkaLPo6JWkdvnvz8iKOSBm0DFs1RlDJclH9oEgn/F/zHJKvkhN82ViOkufd7tXj7uFrwh8WyJw0B1/x3tODbKMM/jmj0+T/WuKJtbUke9DmXNGKFHfBK9NIHzYPZd7d6saKFAMYPaMa9Ks4QFJtor5pLxp0txB9EnWihg47RBYwBhIZHbpK1fuble9i/gTsiTltjTOd19fSgUxG8W9d8a94GjpQM+U87OI+AKDQkM1FO4IcK1pF87BdNweWcrfx58UlqsgcGdyd6qhr/Ujt4VmTch+h4G/iw97QzaH6RmUkt4HfB1CUL3Fekas6okBBN2/fXJVHSYB2TQdfyTF+LszMgM04/QjoCCNm4yDiLa/G8HCL8lf41xZ2mus+6B1cbFnoNNekBvWE2B9Hn4CFCz/HROdDIllAGyeTN+A/DuAbopedPUTH2DM7/h76uIhgZxgUS1WiMcEs5XQSqm6G5qdd7G50ZtMOQUu6G1BsKfq1YyCjtoJ2dB7Qd9m3vGUXHLlh0Gzw0/UJY26CruVLWxyLqiQ3OQcq9wT0dhLXvuqSs5SZov1d0Hyy9NzC8W1O/ZETa1NvdNG6atVRCMJAC68Q2dEwJA3CpbaiUO7SRdzR8i6zPPNWUA3z/vEA2F5wagJWHuJo1nISiej3angBIOdZ/EB2mkLtgopjXF3bkaXiiOEThwdkIFpWE7lY3zCdrnLmMwDn+9SZJBxnoxWJz7b8LU7bZSgtPqA6yRvnaerC5yTibiyo3Z4Q2bU289mDaNmzhOAnYTX0Pf2Zdcc13okEbxU2ITeFQAnikEuTQ7LPFm+rFh8lqzszMxd6FkKxP/AdKppZ0P0XkZhslAaser9q3zVxsYTrdS15HcAOYCSMjXFYTURO9QQvUJsmIPXbfSmSSZ2audwGRyG92aGHbvfKtdp/EFtA5QJ9hCNGdHyEFEBuUYavfZ2eBMilBydfs9/yMoV1e7QfDghibci8pxAAYc/WEW8fJCFTdJf4ejXs19yxMr/3cvFscAjwKa5GWJkF4ZYgauSMX/trJRjISSRzhbFh9KTIvI/Hliu0MR3UhokrNw+borJsjz/LQfY7MraUxVNvchXMjcFyXZoXXWnjXtAZjmoic0tcW3EwQPNAB398uvFeOJ2p19T84+2vTWL8pGJdq+NAzZYA3cdQD44jprkaMwd45UTKMrCGWMbWuEKhGTP2gyqxurZja7pnz1eiOoHZpz4NUudKNKRBXCguBXeNXLIPGY0qZMlAJ3mEa7461f4uxJqR/qQ4OKk95QehnthQlC6CBvSi9uBbNTkAIpuzSkPCcDMcjDy9wQ1k8SOadb/7JLVIAuJl1D5Cg5SfxnyzwHHb47ZZZieUSL7C20dQBIbRm2KT16sCfoTVDl8H4W8P2MJdT5l+9uzcxsaWocHvFolRX8yj2k2+lnLSEK18L7Fnv7Y49XpZoSD5cdE9lDZW5PclgoHPvZ0rntgsI6G0ZskVgCctAq34MN5532PkvqlZJZbOp13qAfbb9MV7/eur0bpguD2jhcoejfObSlZu/V3iM0ti7Yp6aLQxbNAbdFzs7fclHUshzBaKAX4s4q7HtJEdSEFpY9fCfb7ZtSmIbrH7MJWXih/JZ7lYEF7NqIqilpqQdq2/mHYQTWYUD/U5nGFCWYA6ZuUUimq2PucJykVGaZSoM3wA2ukRYFmKXCpRzhEYd+RvRFoH3OiBY+X+DIiihSLLNTGtM5shccagB4rEtKivhsOFpR9/sFSijKJPjhdtHzpYq4mlblm82JFSpdCUnVaK7jHiojy6dVSg+cjvbngXBcNwslSWQQW67mETdkbeaA2iKyfmC3y/+qfQB5KKFjMnVg96i+fMPhzJYHVuoXLNLeq456eB9NjwpWAHZgcAQnHfCZmsDbb2S2VNevkf1k1mYfMHZS72GakGzWFmuhzAIXLki/XhKZuJmdfoKQXpeWJaXefkkmM3HJi+VAWDTZ8Hc2lvVENTrqLb/tevU7DkZA/opaZmQkZP02q3NIj0+dJCPcnE5/xLYbKzl3QVaihlRsSoQmlwdLlQ2YCeGM6P97Taa2ZTVF6rMAYe4RPAqsjapkL4WXeFUjm0M/s+BrpkF7Y8D97QvZ6j63nsCFU0WYAM9JmONDZUAOUZ2IvpMgaYCBC0Gvu4b1rHVFzMAvzQ2BYKikqDhH4RqTTkwZieDb8ni5ZEbAB/e2KNMtICnUcxR3KRkFJowpmiPQDg7VTCUlC8pqXJRKCw9PtXPcPkCG8Cep06OVy/mPIztvv1C4Bj5ODLZNz3khWYJVko4m5xTTlkGTHg9AQVYET1peVSvJPqLYQKceP1aIdjQ383rXSVsNDqKjv3x5bKIpNJtVFr5Vt/T1EPT7mFI42tvSyHW13TSBm5uG2Lgxn9jBHDmlFMULLJhNr9SxuSg5l5etxh23NRA3Akcy2UpEtcLmiKWJdxEvl6K5CgKFG8TF9ydC4exXJ5I+SVHMA7+k4Eg6HGDhnvUQnm+VgRX5kvODcxNgQqn+fo+0IPFjgxGruO9TqHmqPXwDjzEWvFTa84zNHbkFM18WyzVeQW371UBwQl7KlUlua4IrxJ5POmKLdf+gvRKeLzOodurz+/dLTAYL0KgfnYQBktALS4996KopdcNWnhZeG5mQJlWe/vcT0M/b3nSkbiAgqYl0JJuu3j4PYiKxP8tS2tDc1wjaoVqPdF+VKfW0bFXkvq9qhtZv0Fi9LM2ZSMXx0WByTRlT26gNmdNaQEbub5nrNZhh258ZAVmWFTqFObukM0DjTrrHMoWt2ZfbYMWgFFpleQUeCwx6/47g41xjgrUmavDMwJ6JyfQnM7YThKj/q4SVULiIaGtUGphbN/9UvwQznYmaumBzJuOR3t3z/qMbD7sEqnZQuSrBD8TW6rBFwDpQFOJ28AoLTqoB7cBK7y381LQnkf66/XFvEzuFvhfub+Gd8fOmCZYd7ys7n12hQRjRrHRbbhaT1OjvtwSSZoQ+fzAO9Ctu8KoKXiis00rBQ9twG5Ir7TJNLaSo+1EkpzB/5R8I83k2VIdhl/Fg+HkfipWcF3aVYswHvaMirRPtas+lqIkUcfvqK2fRg/U1SXcwPBd4l4aUOP1+iP7YGXe536C2OSU6lY95ufj5R3OVQ3TI+jWJtuecqN3B90/7ZjTD/ItcOhaoXCd6tId3/BuvD5fQ+hA2yPr0dM+58wbzZLt3ygpwwFkQvZ2b3VAjrK38jPN1rgrnFOpjAklJ3xN7qMOvxTZF0dx7F9nmz+6b1vSmA1KUJgotWntmP/r4JicLJtiwL8im9vCr2gSexjDN22htkONVOUVtDeHtm+iS5nidQWMYXUltHUDS4RNJUcWRpBaqSCAFao3NyReeqibjnztLzGOYHZWpm/H+RXLU2PpU11qqktE8CsrJc9+dOZ49qrdbdJ+KgPWNwY8zukf37eanOIae8w+cz+BRPAICiDDTmpbQooWRFEpMGPIMCRakq31VM4MhwQ1A5VXyt4sDO9hPJVIq8MzETnuvdDI7tP8BqVkAxMvoEREwNFbxEojMutukXllAA0kzvkH/9BuohIp6Qe1xfGeZUqADUj1clX9wIs/Q7xidjs1Jpf9yKSGQJ4X1lf2EmZQSEr3xKsVXaaxKR2WEIbn5HTdVfJ/B9tkuZ/mK+QzvOFtoDMibNzwHZekHL3RQmQUPLHn46eEHfUgkKxkdBsGnlnzT4fSh+xbdlprpER6kVtfUImcI2k0d2LDtKnVTqJy4C1oKWYnLYG4NIuDQSxVIdgi6pxkgS2N5W/viaGmAdybrvnbDwDVanitMRVFc9KfJ2dQ7hlJeHTG1uudrzBO8TfnVGPIqXMFLWY/KzB9A1wSwsRUtBJ2ggtTbOcw3fHlFW/sZI+jnnr1q9op1QZWlTetkUONntKX8YM6JCwkjjr8jwU/vddw26gavQh3HN8KkbUIVPBxeEOiksweCcsLNf9nnsxgBuhCLbn6gvyAsv1nMqwzj2bXsYAm6FRqlXQeWwS1+yclI0xAIuqMhOUJPnSmvxUujdZCWCY39AD/+KLqqEC+rH8BFT03kT9qkkumPpE0F/SzobOoQCneHzsCGaMXDEsvVPdsZJB3tJNGiUhbeh4cDqwy7DCtQFnlr7oRMlMscxE8cNF0mbTCIfrY3h8OZokfRgYmrYVT420FMmaIlclnYVwK8vE0B5tCLDL5CmUMs2B82dtTyhhwa+ba08NdNHKi4jQSnQm0QcpP9SklLT2bMqIFekikyP7KzFIKPn7IGB8VrCS4j/BeAt0B3F308SuVDhdwKMVDXVKZEcxRaOjH+/IhQQ+EHznDqXvAeBTRzLnDxITjWaTUD+1+n552eLUH8FnEhJNcukVYaPCfjmeYZZqfU92UM9Wni2s4NAAxzASRkUkyGp5hrgJnagGw7A5xkGV84kthL/fLEHnlLrr5o80hQRW/ZE3yFT01hXfJesBW3X4PzS2DziSRfgVSTfJgk8apah3MEsYVxnq6mfJNK58cUrrodw7wqnlkAXs4LlXU2vF+tuspbiqWACaXOPMHuoOvKlN/KwtMxDIHUqHO0iwU07Tf45TdYkzAc3P8J2F75LkunUIz8QVaphPEtHa1HKF5qb+MLrkD7Y75zJ3K0GXemY6vnx9OV03lhKGkQww2meeqe95XUBYFTjK3qoTQr0YdhjnIyHlTuJynBsCyAzShIQJla5DBbZ2AZV5oB/IpKJyXFs/+p6Nek+e8DE3vJidma8MytftITANbNS/o9oaBDrbwwKrLpq7J4EFZrleKzEe/C0yQkJQxSRYIdh2Kbg6jb6uUlpKLx+G5bRQHtGdTd/KzfLI/dsw8t5mFcvn+thS9oY/wDzvEyL/JHdkiOo7kfRSMd3B+X2Fnb0mbjJ9o22EDi+Ipq3q6GPUxydBBiyA4haxhnp5z99f17gM5dZN3DzWDQNVWQ0cLU/stsKzBvHMWkOcOFMdzEMDAIrXNoywwo3PTesgIRiqymapXLIMpdtuez2dTpssM5Ce6e3d6Bq3Exw+s7Zap+7DotlsBNgnGBrEAlrtX+Ub2o7BsFB+Sq0DdtIABa1oyJq1pq43DyO1cHJylPefnO3OBUA3TBnoM0k2OrBYeSEPHpsC4uoPxuaNnS0gnzQ9ZhF54SFdCSYf754JV+iXQo2cfviNHSx2gI2k+0W7PAJk+jaSWIBdPMZXWaRY4lIoD+8ZXMHzI5BskJ+cc5cLpUklofn0Xe/NcFDXmAO0IqXYWKCSjn6m2mkKFJBVo1D/s/gw3+CHb2fNJO8uNk8xPfmcJD3MUG0Surb0qpAPEawPtxq5irCBlpM7BE9jb2zTzq/BD7rBQbBWkHSgTr5zlo1wtBblqDgJketYJUMThTDRQfKPobrkLLvR0otbuecqkcv3YKAR5TMPb1L9MNyMv2ydGPcOYEad7369GjJpLCDCCYIpdKECc0ZZiKmSa6Xfmop34CqB3I0ocHDE6uxK2OudhJg1/Sah5vRy1UasrKBJsnfXp0HQcp2s7jUYfxiMsjARsEmLax9NdO1oJOkquXBhz9y4Wu3NQZD06e70dbtVLQV1dsB65OwDPeCB/G+3e5APjDW8SJO202Vi5sBr99LB3K/hwO88k6Zu6fEAT4cLFNESGnekVcp69rkvOpLSDXsWQ5JOmrdI8beGrKHtocb8MsqhH6Jne4Cgaos6zCYkeAxuRsptRzI13edHOB9lhlSnvvXtMx7ZvHOFwBox4o3nR0eDeN5ZiIgB5IiIogl3+FfEIE8jAW2it6OfFQ7cyHnW+17Omo1W+A3WT5yTK904+Cq5gZGPXR12LCXVpP5rekJo7ZEOiZ5vGm0JZcVrEx2SZ2p/eskD15hERdQJ8qHz+I5X8A9Izg9lKUCVZzMPlbZa/M189kI4rq4yNoDXZdhErD3G6q/veZn34NvN5wB4gY9l6YpjAgBGOQDcv3QYQLe+gAhw/eycb6xDNS7VMJrsmpcAxIL0AyzbManOIikJG09MlOhI7NGxGLLU4qtXf2pObunshvI7CUbdQmuaKu/hYBLVLFEO09Ln2tacHB1437N3LNzojRoeOdweRv1fZ11UmAvgZp6cV9Q4hU6tQ3dnU0gJQan5a3pkh5JFDg6OfVVoN1dfa/4eaOaFrReU9pzOP53Oi/DLDHiO+UibNx+AV5evB7GVfXrK5i1K7ZT4BJosvvUSLs3voFKwFwpXCGg3XwCI8yA0V0tActsxDH2Bhr5iG766P1kCGi2kUOF0Gc10ZbmFb19Bur1tZpIs3fKZieglD7OkxAgljuWt8MSC6+yNXvcgt6QUOLWZ/hB5BKNdyQyswPyevHbrjEe5Y7+0tLHUvsaoXRY8Qz6vzMCgMGs99+hJ+1PZiItIbt6ZQ4By4N8FkVlQUL5QYXNXi5k2OoNNyjcJ60uhzN3a2Zqw8SCychuD1/cfESa1oA35w+Q3w8Eepo7Y0pCuasDzPD2z33pekZHB5N1k1Sq8LTNYMJ2VtwjYxotzOOBRBMz4aX5ScO1emQz/axvIG8P8EKhVvUQE/xanyEUwPm1jhONMY4jIymwI7Z2CHED8gvxgYOeIRj29oSO04P3hMTYX9GZOgxbXcU3hw5EqMXccjtP5N6E0w5JX7wc7dMSWdQ3Z/zrYk2Q793Gecv2QRYj6rD9tb3T5GxJcI/E2hKyJUv9a2eXoY/eOaJIW/8R+Sf6LtplxGGgI4y29xV28rN4oilfjbGSQuaHpPZX+kIsmQSp0+c+VEjW8N106xQz/Isqb7x9UMZUCtRtu+4W3Ftcla1KtLHsdM1XKvgEE/L08ePNEaAbprEWisWDvHnsSJOr2ku/bSP9XwRxB+xQp8p9XKme9t5a7EuT6+ls3A2psYkjr5Bfuv9OXpKTAVP9xjvQjlSJJ0/AVKO5IuLWII7NhcmR2yRDiRA+gZ0WfZ4bVSeptjqVFnAEIg4nz2LT2sLmpY5GSMC377/xG4IiZ9YN45Qf7iBFj/dOQZPPWUq1YWHlHpuIyx4DuGlvHefJvnZvQhxMAONxomspOI8yD3QG8TrbFeUj8G7tuLDBzcfiSN9hTp3Fsbh2JAnBNKeeaqa8BvUijdG47BZS1ua/SC6wGRQFHxzfQFMZJ5N8hty6IHeBuhIjSErAvPBWBpg2cNwBURFdQ3Xe3NchPEnPetAGxX3ZnhLy5zP+fgvYz0InWc3AgGzzF7VuRQ4s96SI/mdbi/Kv6OQM4xHt4SFnqIj06wKjkuNAuqj8AF5+Vt2ILGGXLAbmoEMx2Mf30FFM2ejjKahr4SahP1Aph94siNBwLyCKLRUnX7r+v70PELkNn+kZD00O+QIrN9Tv9K+LYd1VVPh6Qs0rdQml21iOJKGJmE8DwyFfyibfytmI0pDmhR7hVFhb57LEVWTLeOAKFqUcBVLct0UCr/PeG2lmf99FJ++wIuH91yJTTuDzHo6b4lYGApBRIZfXBLOUMriDXujsl0/mYZgN3XmDB6NOc91mdH49O2JsSchY0KD6OvYWDNwZ8LeqnVltemJ65IN5myPI/Pu6vHz7XEuZLcJAWZzPBnPf6Rd6K4BYo2nYEpYq509CRV5XCa+Z8oE3rJT8pYSrjArCPzxZIZkteD7qpVONzSDUP5kCEjTb1jnN+jQlrv4vtXzWT2M+2PUGNOGKPKVTIQe4kJzOXmAJq0U8eaQc1lfw4ojp/XEnW4SU1cAAhc1FsAUiCeCdJWKatzYJRwcYJop1M4LVdZv/PVThktKUyJwgsuDtODymBhc6a1XCtzoyM2gLaQI1cjBNKgM+nfrb6XaQn2OqoPxL5VnEzl8NjbaSnsG1YmqBRjWugFVbYOYU5s9nE94NrgZ3p0Mx0Qi2GcYAKnom8pyD8z8CvAStmvYxDwFSVtwJe5rSgl5Gb/LkHugV1pc7OCrQMzfIGepgWCTMzmUlaKb1nUgVCL07oZNH+018W8UunISjNkT5tllOWHePRJKbxcqUO2G95XJ3Et9BxHMxac/y7bX1KcT7cW/sZgx5drTnOl4KU/xk4nOv3GFwrLZ9Ek8DBMPwyeuIrIuFeYJcLIAFnnEraRjmExg57w3HP9Zu8omscdsQVNDS1/2UCD0+2hdsqNVT9339TjqxJZ4EJfSVTI/aR3R8/tyxZB6/0iwJbF0a0bOTD+bAktGhPWxWkG7NMGPeVnPT7H4YPcOvxpDvkKJqcYx3I5/lw61P4ibCSD5Fii3AuI4E7PBwjQu8I0rsvXPBDYtwIEkMmehGkLbEGoSfvv8GPCHyiSWH1NsmUjNcFz8T7o4awZCGovTniweaUHvUnlDuckc9WqwDQWjbnsQnR1fVgeOkviSGX8Vq9jdPAY9Y6mEPCZLXAr0ONT7jsuL4bRV499EIJt7wuzIs2dI/MCqu3GQ6rZiVfDBjPxygFeHO5LHjTX9RscjG+i3ha/nDdJP+6X9BXcStkumXHjiKIxShPgXdMAmtIF5q1iyO1Rm8pvdbuk00GMtarPgKRdk9bwVGGjkpqvOtr7G8ZNFlDOP0TyLDOlmFPIKnqFr4exUslGvSfRENWlh/d06EzpATWJca+IT+zMVFaCw9ICcL3AQl4M2bZqDXio+OTYMw7w8ODb3ad65csWc9JBWlSNklLolFaniAcQAEzDjmFc8x002d/iPH3COrQITB6iKfuVKWC+fH9P78weKuDXg0tpHCqIRwn6tYNvZE5qggnSaKVHzbxbjI9ELYMwBUJJOvRT/o+kXtlxJ1bM85o9pQ3YYfLQ5OCY7dBlZUNps03JMg9fvEX5bEISwNBBzQGn7N+0vaz2f3H6djyTTU62EbnKnOMLCgc6yU70jhED4KMpitx6UoRRgV4820ooxSYaEKCmZNiS0YF9zEPkXks9aWNWz8138rezypc3BUD0Sr8YgmN9FE3quSeOQvLjy6gIOBN0nl+41U2LNN2Rb6P3AqMoqoizQQMshiFMjuYjoSTwkSmPTz5eg8hso2qMnau0Z/KX5rp8HWHmtWFinuctyTVqZemhlmIq/Bvm+k8iKiI78OMhOYJ3ZhI1LRVwwq/Ugcr2bWedmhW4idA1+RrfkDixja796y4verw2qVztjJa2aCgBPC6KF7gDAqtGDJSe8iMzIDeSIDL3cIwnEQOsPIGrjUN+xY81Wye2gJ5A/9l1dimY1DjFd+SjfMZy9fqmdhwitaiMQGsNK9tZXRijnjJv7WzGODjP7kO2X3qs6/p6Hjz/s75/1o5FXFYcicB38gmE+CY0Zi/XcnVpEOgDFmBgMZK+xIlAuLE9mt9C0Lqhwr4wVv0CHcTutYMl8E71G6HQYziOsiJPNHn3DTGXJAySuW5NcyOlSyRW5PTtjjl86UI43JFXDO1jTzmLtOhTNqxb5EUqO6PKFiWWn+bzOzodnWmM5tLqlshEtefVOocTmzoBnijImgp8Sm6EBmitItMGxeXvCyMNO7k26bqLFvJGmv2Vg0tUKf1RulI5/3tWocQ4EkI1pkYMiSe36hLiwt5tvESwVr68eges8aro4xEWbIGVxzoTvioqMI9XTcP48x6ypGywYH64MUsQ5kHCY3vAFrA+V2pAcWRfzzppmy1G8U2xJZewKwpoLsu2SjnxoFFcQUWy7dWDctCgR+i3BbQab12H0b8nbywFeANIMMhQ1NXdMKYNDIuRK5FtLpMNsiTVFaiByvW1O6oZ6cemuRokK3XPKuPJsjuJwQieko5W7JFkkjlBPdh0fr/iEJJvIAvymO3i9GXLVBHYQ2mJhwURklLITo8YiSTbrKiyDG/2ypvbyS6V2xz/FMVRan2xfYduEpNDpRQqJB7L/zSbeUyYcNy/tM5IBTETet0K298J+UO3tR+GRFvsupIgiaBBFgTGIeQQ7zqv5Y5aUydmmZB/MciIONzoMlkmXuy4D0zeD+bDVE1DiAfNzaO5upyRUSSGJPtfQfU2LMP+xNrkX7Lr8WN8Cl496cM5dLRzghKVMwGs4joTzw4/+OWDKUnwmrCBUs8Rm4O9MpYVTuK2gw2YYD6Sd6c0GXMmx6uQfeKLjRL6JOHv3AqzJRwHIYd7rfaPYHSmbWV2f1qNbFWjysYXRPu2XJFQLPSlEj4tYotTNwRp5fTzspRB6ROBQv1DtyEPXDR9iGKfZ6S5w37Fwu54+vhC/op7SGPXxcW3732svJhzpUa3IztTRr49jRNOcdFo2aBCrBV988j8ZXe87jrrT4PDV9nEL+IDr/z3j0df6DSy5uEM4V4WF0XHzpFEQiP+Knh6g31uh/CzSbfizQEFaMPvDoNTVD40dFiGQ3zVjGfxUMs1ET9Fd+rss2MRZVJ4SA8un2LdGkuFNOiXhJAmhz8/l4y3Qi7tYSR5Xcr/OM3j7KFV7OMJP82u37u/j15IuV7AsTGSel6VbDEsoXQJDhwJIJwRAp4/R3XkxiwNOYSeoefqFlf8kJmJMPAr3q7TuY8WHfI7BqbHk6VnC8T3Lp6QXU5pUUEU/0C+DSUzPDC0mgf84SehiHWkmdwyvZ+vj/MiV+50bBg7QsvJ5mkRcadkjt8eHYhqMqReo9XEh8KHdzltLbV7+1+eyOACwrYakuW4hqkWvkbVNUgKoCuheloiE/WUCo7l6dPtvtIGlnpDD1Ew/SCTru6z8N3ArwP+q7AaDoLqwox7j2zFSsbk0EWHBST+VcXgvQTWuXJhQ5j3qVZWmweSyXbiicVapd1uH5/m+/HBj4bucAXnAsOXGcN3JrkKcjROSnCVVj19vChjX6Nddf8DOc15SU+KgqFVdy32IVa0Da5FI9FH3L71zbnDtkOatN2nBdAV8YEB0Uae3WAUfJ4o3xG/8/7u8UP9rsaE3pZStcAuSp2ZoifLiCTQxO8bN0NsP1zPXM77ONyL+TEfSe7jGYujXkrbC0lPomAdbWwlb2yJ8+XkkDMISP+W9fda8Y81if/cQcYuJ/p4nXQWBed9O7MgvG4q89zNrEqqEMKsqSzi9hm3AxUAYAsluPwJlAQBM8JZlmyQLmhW01JfR1L4raCIjuKNP4/w+BnQWU6Q4srfh6o618WZGeqkt/2Esd/y/7QZ46oT91czcraWiODVnzpW/5Hm7Kn7/WZRnR6fNaK3Sj8FRPPCdR9cWyfq5MQduUUq0TeUAxEWRy0CobaJDnPpSYuRnO5s12jo5RRLyOV+2c/ErEfuCeF3tagSmpxcfmkLicXJChYOn9mWc026ilACPGnDh/wohUGud8Q0ROzcnnx58b8SHoXptro57pR6aISwV1YwCyCWUAW+d3MTsDacMh6CcTieSe4LQSYgAf82TrqlUtm376oAZnN20CqvsdKdQga9LUpexcKi+2kSmP1vocgXYbw1JQ3MyLNj1gljF0CK0dXQHKNCcJdsfg+HLg9mc1lC6jDP2w80KpJ4HTFjDQ6UfwHecxf3q1Elb9V8dQ+5Pu+jN2B4k2wWwX1hxaBlubIHW8zUPIOzxsIGz0jXntV5G2R2LhhPjQy8KpeTiKQoGbbHe0NTmUJ2+1WZyhR6sDgAV34VL2VeQ5cXFNMQB87hXCcgnMR19DWBI7gg6CU3OtFAWqrY6BzvhdzcrpNKfwFg3BdZjCF2knV48BP5kNWMiihvExViz6SQ3SToJWvU0VZOr4foBYvQwVTnnhxmKofZb64WWxCZT3Fz4ETgGoTioI6QgurAyvTRHXOI4bxrZIk5byqFk7Wgd+3Yfj1OR0B0uoKDUuetZO2GWDwvtBfao8SzojQcSPTUzSs6IEbmAjFStzmBtKPBRaoslElmqMefJ5V2jtGqmHpa8FeBLo2FZgv16tqs5d1ihEZzmShm0xhEYdXLYxBYtmWuMYiHDfVHWBpwUwIOY/VAgKxW+MAFI160FbsLkeg0WksGGRpczb6PKI8sJZ+BpoQv2cGz3o37ex2JxkkMde41hzwuMTJeoixexkwfGX6kCJxKM7E2gNZt8OrZZu/jWzuxFZ4a1oLVn0ttLJOPg1XaaetxYv8U/SaESKZDe6riWuyRNlICLFQcAL10c3ER7BVL6eWmNC8ZZ3oya2gxMW6A06eAGDLjn40v0jaODXrwjt53sdTIHqKxukJ30c6joLxV1k0WRn/vlF8TgYwWh1Hodc4vrDSwmcgcQMyX6rM0AaJgBq85reFAs/D/RW5JnNmr3a5kZ1bfpXiRVvGlxzXDPk67CCqNNywg0vUFbyd0awDKfftttfVPP/ocKbJtUkuXZUeQIcsUUOlGK0d5kGyTIawe8IYnRsu4m4OAKdfwRPojgMEKfS/Wnm5X/5vsja5cWqVn6hQpLPj91vT3LSXkeQn77ug5FE6jp9y8QGslFk2AresEkVHDBIurrIyYlNqV1chhFOshf9qXMP+JOhITJu62Z9SBerADxT5aoB5Xaln/9jw1W0p1+/lOsFVqSh2JNoe3nPQkcYjQ6zVVFv/XCUpDyjA+KYYxZQ+92yMX/F4lamJCAp0d0mzXdddEdpnQOzm7Q54MdNB48YGK2aKsZYxZ/VLBg/Xvh++1n99DIVHDaRyCCyfiOuyAbnA4RYvfZ1Wui86vQCU+AKsvrkuryYS1znF0PDQjq8/wwe2K694whS7cggUBjfWtdsv9IYd/YQJhEkqMls7IGtJ2WeuDaeKAyQRi2PAwRKCNg9J6sZtcYBZJ76y6eH8f1U+xqCT3E9U8KAcsQ/5SToOnPs/2l6uzfkINyhp/H0DVqaTn3I+hyRNIdlrkoIgC6j2E6WCmRcODSNAVwc5Oxo9udqc23OVZfbO/QLdiHn6ItWDjQXRC9VUt3oemc1YlyAR/XBQOKq20Z6+LhYj9bAVUfuKONRa47wbkajW3ow1NlflAvX3lxJBFkvvwyWm4Gl0LFltdWjCsU64wKFHv7o9TjEzfwd5QVki255p8vAYmpuvqFaklkcxn/3vT0J01eIHAzLzV1NeTywxyHqlqncsgBcCY4XoCDK2vPFIPr6XCPoDO5VduLr8sCPqfg/oxcmHK95q4dfUgI/KCXa4dzfP2I3sWCWVXUBGkmkZQqolU5WL2HhLG3n7Pg+rqXmoahMKV+itAp9pM8aQjqyuSLjqIYOGWZVLUCkFD63xVB9sD/0PejBccxyfCH1JuhC9iwx+mTvPEQeA/Dx/tDODQut8nQPKoqB8rQvSzqTStU1gq5v+8ZgPB1IbwdTKGf7zhKwPH8DYNXC+iJh3UhrpLT4lnzr7VyxvII5UV/ywKo0Y2H/Er/wQaTfDLKL0qLHUUrEwLMGZrf7DRMML4fqljT99JST1gFkcTEU/k6jI+tGG0xhkl2XKNE6AZusE4hk3RLzQUw8nFGk4B2M3m0OK2x+TNoY3V2DUJWhD5yPvzhkVbAKDkc3jezuKLtuwaLKrbY43K3jdY8JY27FV/EHg9dcgsPpxG4NKxikYYIh3dAWOasnVvIyWv1zdwbvUW5/krbrz/1JOVzRfB4tgHZuEQR6YvW1tuoBSbTNdfO8h8ZzG+PmcnFlpYX5RvbGp1iBJ8wNBHeXhgRDLmPgxnfO/zd3bDik5k+ijbucbMXGS2hVrRD565MvwCoapHW9M6sULU3c+qEw7PSSEcDXG1fsF1dSCLxAB9A/kpLXnbSowvIZMHXPAAnyejoSQiBt1/cFhjT2OlNrEMxWfPoTRLjNsbPFhzuTwZDJLNhQ20yPVcyH3TnHwoc+mnw1UiTqGmGCTwafID6kxSbxU7h2cmGV/JiRgapqJS6oB6dHMPBH9CNLO5mqSzpsLIsJl80baqy9YM7i0jipfWoistIA8fHi6xAR8WsdtjgIUBEAw03kFmphzStRK/KwuLB4FUDklN5dDk1kawbnwXb3jHTPZI4eiYpd8js2EYYknp34E3FRltQSbLJguJWxbDAlOkNi/gQrKi+TyuVhLIX7G2kMLPOx6JZ8SJFEevWHUSKncOEdF0l2ukRBfJ9rFuPOLR+AX+MVvOyOaouB0H55QDRQQRoG6bcpYQSmykSkIPKfUns7kzOYupacNOYtZegvmOQ+8GjPwNwSBZikumiu5RM77jtQcik8rHNgUNZ+xsir6HHG9FapNh+g6V8bTIeiMIaJlx9XsCPbutjgAflqsba+pU3e+sCXki6ly3H8i6N2bCzJAWRWsbjIYQlhPgtpd1gSQZj3p6pZkV+ImoJJ3gSxAmX11eGVn7N432+UFs82IfYc4cjEPMhknaOJbisLWKLPe96h2GUKs+/xXNmsKkLYIJmjW8Q/mD7BUeChPjjRD+1/X1s3GNcggGCS1EuRX+S/9hv5DdV+NZl9FF5Famb3PBPgd3OXVE+5+5sFsdIS5yDR8w8xbG1OcrxPwbr6yJvFEoIpx99aFlNheUpMo6O9Sbve6onZlzXw8MPZ13gNkL8QfnH4Dj6FhotgYGx2j+F8PUdm1Yc4pFQTweMcfWYpX4Dkqh9XaZAjaR0fkWtHbVFetDLXb9yCmgH47ncX5nNbGG479KJYU/1ekAvnuV9uVHCaqveY2DQ09uTxIaIvVMWNQfvktuyBvHILOCch8x+y3oLL//jHdmqARZvy3DhwfQXc+bAG7H7OQhgYvARThlzLG83ANgemK1ONV1GoYo0y7qiBYthl+k1rz/L4tBlD2r9Uc4xGfX5oytCfLT8xoFxre4ykagrl2uRLT3E+8gSTYGogdEa6a0mkmpW9EGsg+iqX/VadACHLPJiVZ8VPhZEmGesHT/I0zYAAOTfAWwvXC3YacQRz3Xsxyz9sItg4Iq5KFD72gizu31goSzf1jeTiK557dZK2nkIVluRhx9mQHd7PMRbrpEbLLIghj5rgIUE83ocAAFtFAlOPJbWPqh55NscZoBGQvFy5pzbFvQW7CSzorLO9tLPRJcJZMTSnWu0oyDFlXFBHsVotdnUaXvcQqGaDSiNBuuh5Sif2EBzdmqMyQCiFqO/NpbD+SWvi/pTtJf2a4hIyFvfKdFiUi5Gz+70Mj1SN0DhgzvENwq+m/ZEYO2lyfdxD/JaR3O9lvKFHC8BiCccRtQwhoIhDztmFLhhIHrPGpPwc6EkXMyt1xNWhJByuli0PboPXHPCrE10z78GQaQDOiatAEvL5+panKPnfm+6an+5qAIXS6rxSynnZXk+reW+EjJBhib6+0YL3CeXNxt4ge9U6DIbD1iRwqh8vAgj7VpYJkISOqA0tOCBQKAkoFoEWwuuPHHAGmCHZ7gTVvZTBezIU3D0GCvmRTWEiFFVNHQULiVP+hTdwonopBVcH9P6cMhMgKA+LXEMo/axxXQUU15VO37pVtNiHxkFrfNdzPme3WAQt8Q89Dx0ovkhk6N0MgUC4hIKtDW729Gl8ZhUnB32SFcO5GVT0BPpTvAz+5rMPaa+4N9ePS9FqEpwLmD0Of/JwjNPgeCJBfbReX0vulb6n5/5Vwk6q2lnMFrGxwj4XhbWtMsyWs8e/9wXo+BYWHHJIcdybQzO30EuaOmUNFO3ZrRc9UzPGxdPqTwRmJe5yUXtunx0h8wUFcuvE4sAeJSkrAuvbjNGegtigt4IcYEHoh/HxDIw6bWx5C5oiuWovZ+w8qMpjtdWf/lx46LZgNpo2kd99VXrBEA63NqYH5k7Us3sKfwtyv5mehGuOnEDj0Ctm7YUJRrIwZsFecYNZDBdmUIDrCjOeQfrN9sHL0igU3iP6JKR9HsBXecNw4kBP2LVgeR+uZHMQBuqwwTjn14S5HhnNk2ubJhnIpxE7/WqATLObxK0SK0dkmKr+J2H3imKWgKm7nojdwnrpKLpodUnzbtXqdKmBDkatZbvPKCuuTN2RjNoWTXzMk7Hjgmb5TjmFnIPNBuXaGG8bVU0lWwtrmQziGajEUdkjaS8nSprZnV1q7z27PkNZXjCGuZEFVpoHyv4RoWVJOSGsQeboNZVdE6V3/YWNNoWhJuDfN2+iVj2CblRr7Jrr834MP6GsaD/0nX71XPhlOMREqXvFwYwbu9o9M64sYWev+rzpX1L5BHqPhiAFOWywWz69kUu6wSdp/MIlZ6lsF+yam5XoYVbs2TH2oiEG1RoJ4PHqK9blUtNZ9gF3vCqWu7mkrql50m9RUweVUGFvUS67aoUb6XtI7Tc8c8krPm3J2iE6jGBfMqZfZZNi3YHNwCj6KAezmjHbKAPJQ/q3eKDBfisT+LYtaqiCuIbrSLaGFGuh0j0hQ3N5RWQauAmeH5M4t27xXZGBuH0nMNnBahOHMVKfhRCAEChYIaMg0pPiwbXkKu5O/opQuhMTArBAoY+StEahxDIJQGf0i9L9nrVte5GaS6v+APFPwGukPDSS9jpve3r7WxjasXABVOlySa4PnfR1kmfm115OKQk1rsDqygu8+/3qvi/N/LieKJr4fPmUqZSq/JN3Ru3JRZFS8bSEVIbA2FY8z1fJnUwaGSZXXl4Sqc7+4mHi558nJlvXZew/btVIdKkCwgKXWlawUl2xCSWVX6/sYj9qIgS8RohrUqu1GYxpxDeQuWPIM7gdJQ405+HWGdNM4WxXOveB/SCSmJp4Xe8qglPQYg9GIqqmahkPAYYOkgZA/qyrAA6zzE5Gm/MSObRclafZafW7nzH4Z0NoO2N9NHCLPMBgLBdjffftf9uH/ZxidCMDMve5o4OqKaUpgNCS3ZSAwS/BAObNY27p270EnVVOos0jX9XvRQfh7jatPsbywrakpdpHknlBptndprVvRXYpO9GUV08bGc93Z65FE8ZVzz84qO1bzwIB/lWgyaj0hCHxlEEq/FF2z6oi5ia/hYtcFd9D+41qEPXT2w2VaKXO4tFoZq7GAhn6dNnTYJLMsm1tFnHMXYseZx3r3Zc1GUWH9kPp4bQaVnMWVL045QHBIFAWckJVVGdL/e7hPa+GYZa4UHlRWES58Qgr9Qd3aw0SKq1Z7gh5oT2rZAv5sMhFqtqRofuGESH5f7TwNEmXwKvkxbTX0jcvkrrOyZkuRjuyCpO+pyD4PEfll4dmzskmuIAJR44vJTUrMfPIx7ChrtkmHKVsTITNta2tKCYIfw4THKtIvrgpxb5YgsZ0ncD29x+mcXmSFa7UCGO5lpBJgg94uIcPXLQri42mzhm7jzXhPDD3CzB85bXr55uSTIDopsx7TchL9KfVjw9VDV0NUvjEro1+0TUjPjNYWibw1o/pZsQktiROu3DQiuA6R94LC7u6ldH/ZnF1ihmNkIJ3PckWj0wA5L79Uq9HTPWGM+QyBuJDtLdWF5hP+5JGxU4bgW2wBAiApJZUvabfP9SCz3neHmj56sRihEg13m45rvNoZ/hNBp7L6gyRBgJkn5Qhs7Pom+IwkA7v654a3DI9FeYYwVZ1DU59O/cMlrGHCVf4mw0iCQalzefAUneAE0u9OUD1ROQAwDHhcbEQ4vC28JhVaT5d07Jg9jL0DS2pR9AAfhZpA9GXqyFIAYuScTtpd2CdModH//OKAoWmOjrcFgsdrG92NnoGC3jLTVlEM03orvNP7hM14jjZFgkcYm2cGYexyyLfpVCAVCwFD7cmMfUEHaLaF92XhScbVgPni2xUiJ8LPZHyvycXKgrNWb+7SFXIuThkhWUGWmXV+JZTNk61YCK40eDjFnfyU0LXxWkvzDCmFEgxqZZswJ1dNbqk3rRk1l8UR1fN+4ej73mY7tfr7uYbVmrZVtFAhr0OpKskUp6ii1c+kXtH0gal0B65R6kEow+3GkyuZ3XIdiSBGNc0ujJ13jk2wfHTI6h+Y4udo1VtJn6cJ/BRM8QdBKuXbnr3H+6dW5fAqj0gsD1UffjPtzy7ZEQ9n96U8sW1MyAgDwNH7xHwfPsRB1rs3zMunvHoTvTVvm3Qz5zi1efdDXwWckQYLoXw0O/HZXH3dN0A0YOmU7Ko6CBg3/o2OqcLZtubFxicqfFiumcq5eXO+WtDVxmDvkHUlBMgS8pczOqKtYbbN1fS+Tk+79BrT0ystQxrcSMwSycWwrN3c+wjON8UUhsAW4QOFFy5xM66vzUkOqcz5KpKED9FPyza2Cgvh39Yog7X2JpplWaTOvBVyV2SEQNKLOyNCvqSDwAx6DUljfTJyV5jYewBsgV6tB6vff6h183r4l5UK/RanZmZJZ0uxqGBMk9ZH1BBOmRlCoAyx7t5Ex2P8Yoa2Ysoup4WVI6rrlxPVJwdSRnES11111MgndwDtWw4zxNeDsWI+9tcdTKXm7uSqy04/Y+oI1NjwKIYGXA7xMGtwDd8BNSQ2rKWWHTVZ3VNZlQNdmjpy6TDbgdFgr6XXloek8aPonVXjaJ+oTh2fqBd7olHoinuDPU81aMUQWuuVt1mE65bKGJzKVuNOFfB08c9WvNofDZK8qDrMVh2dQGewRJPpY+K0KVfp6yx3B9tA/kTagohezZqrdzH/2nDdWkQLaZz+jYgBpwIp1A7mSeQYoVpRhisv/cHHfR5trVEfAPjl0wyLIXHqDYEoojCkCP3eU80IjTtN68xloM3nhRNa2jYD448Q396aR19WgGf2gVDvI0DwlbLtiwwzyMOEx5fcPNELCHISrEB4WBmPUl0FvTd4zidPLq/43oTt+95t8hzd37FPR0FfxMBXU3c+fov1VvNFkiG+nNYPQO238O3segdLCBNU9tVJtozprJQuPjQ0aZJWZTsq09aDGimYi+tRCrkQ6d3nC1gq/aJZN1fYt8Bls2n51Psryxlh6big91jIMiWPNQSasUp6ULYhGzKE5yMdKM48sFPDSlWalV6chkIg2N0VlsOe9QjQEW1xVoot3s3IJEQ+Z9mJTo0HKVSltYWN2W/99LSZAFJxTPg/LtFO4yDvK1wrKcIfVEy5lUwNLEjoEjs6ny7OANdGZGSdqxjjt6+o0yZ280nZbmvUcQmOUA6/x1/bzFV1Hx+m2BiOLTA0jUOOvVHV6UuFORSKh7g9rzOVzgA7YF6W/qD8dysC9yv0EtJFocvkpi9xIa10MGbPuxZAwi3tf9wpuUIB25hNDeyADliEqUIeaP3AKRTiWIttKuGy0+OKIuHe75bJMXvUwmwH0iZ5BQLiCwmMiTfLHc5r8b9DAUa59AW5z87x1dJ4YGK9kt+3N3Zz4GLeQghUKE/AdhpRJ+9re64Es/+61inAW+i0trqhvpIpUyn/R7u3oR6owKkBBK4YG6zWBC0uuSJ2dKXjxjP7Lv38DUM1N0V8lo+APHNZn3LYvg7ToTM0gcgNjm3USVB0Ffxk0BdpsUzQqX7gbS7ApYG42Tyv1LL9AUW8rm8AOOS4Ie7CXYEf4DlxgrVHCEIavpK+HeRtDDj017LPWbct7t67sz2VVX4JnomXAK9bXMtj1ysPAbKh+eFXT3aquKSw8XXvoBwfUUN54p/ozS6PRB5MrCwnz+ZxXzBCIwP4rE4TpaHsYd3GAA8A+64Yk8AzmqHkUlwTcwmSKG6JUW2Do/7blbRXelouGUnThNk38kwFJjzmBp1/SoM0SAtFZQTusU0QulDKBIVEW0r+kFs7Eeh+O5KbYBGw3N5oldIjlnkft6dh79iCvyCGPGgrelLJ+MhM0oedStMjf5Kwlz7HCh9yncSoTjgNVRaYcwNASZC1CqdhlSxCaaWvVgKU/hVTFHtzKmG666MWQj3JQNFb2pS/k4/LMfPEB/nCpwiB9IrdyigpTkDSyqrxSPxDwvnWjcLKPN+asqyVI2w8inOsY5u+3H8jgRUEta6ypUW6miPE3Lo28rIy4K2Le9YPQ3dbFDqRMdZSLjDhlxvVlqXgbDBD4IXy1mhusTPPePV0zpb2NjidRz8rUWSkEfXYDh7jRnTmMKQAXLps855MxcumkoOKXXlcBxs0pPARKNoLTEttczeS8bvoyCv/eh3kX1ULeVMSPYsja5zmlVczXDaWLU/pYk+4HA0YvHDqFlmSDmdmBFAzd++I/Oqfm4vyb0kMT/yH5WqSnM+Uwv0H9F/RJas4QHYfRZY5iS45cdjaGs8rNCUrSIxy1qI+NlBrbcCxO85eFchvLHsVOH1FJfX6WxmJTVMZbs9KQGXTf/ajNZjYEWW0mm4iennzuC7yvQ9iyS+x+7d1ZIln0+5HYMox2XXxPhpyNldTDVQiKS9nJQqS4hEsnEfOuK8XAAqyOxHpsnAnaTBSMqJy1VqwpcKIRr8oqh/5iIasnlkZxhbpapXIbnWyT9tXQSQVrJzANrGSU99BaIN8y3NHjzRt5TmkoPeVb6051Jt0UanfrvGYs+AdS/zXeGzkd1xoPdohSwQTBPlE6IhP6ekki1JDoYm8qjBEJM7GsvvJZ9rdMZ5nO4/qfh/Pjjsfj+vdWoRVB1U2tYwk5P1YPx6O6ZENeRviSnECy36aTCk/io0Hoxq3tE/XyXQjHmmYQ8HvNBRDWOE3UvEoyE2II6xMkP7BV+f9Z8gvlQx/TyNugKKMTl8dbGF3ivv+fZNBCZ+SJ/mnztZCGNsYaBGoW1bLSD3iHo/HzZXu3pqoyboT/fVjX3ahpeUOHEWZnM71byUiXja7soYDD+M75ybt8bHHhl7IXOarKkinIqBWjLLPiDecjSwDWaoJg5pMgjuX3c1c0JqlboIXtUc7QrkHUmBun2sx/sJ3CRwqC7OiyXxDzvl2Ep8iOfzIRLz8qQjWc8f1RJjPfqMRzAfzsFCFkfESpBs58NU/Yq08R0Nl6ehOq4zBPFSk/fjNv+/JWQjbpCtyWYaUGBdEibiMG3rBq6SrNKP+rawTORYBrgnQx14oDvth+MrSeocXCat22MmckUccQaR0/8G5z4q9Q1TcqHNmjpUyE7ubydUaO3FN2AqGFUJDx5iXVB8JbzxqGe+hRdJX/zALkQCtNv2TEffKzeBnwdTYTdJSwUGtKiap4OA4DgXS+M/nRtHdK5JZgT3XcuoPhhjOCxqWCXd74fX8ta0LfKZJUZEXYCObxeA8l5X3cz94tTjf8AaYKJUZwXj/0JNxLuv2v8rRQcAr3Nr1ykT10JBNGX1DPV2o8MezOKKq2z5WmBqUTEOP9u9ueIlZCfT9kWfr2VyITijmsgUWxBY6lh6JEY3jbzQ/wuus9Xpdz2Er3hVUy0E0jl6BiqW0m/ylT9V9MF5ykaiw022tzEwVzOLT6ZW590L7+WoUPGROv7F+VcHHD/3p+dltEydYWlDNWKKm+0DW7qxjB5tdaoBZQLEyWQ971jjtMZcUKZPARG0noZ2g/zKpDFavmX9fuf1pD3ZA7UJx5LLO37vQwMIGuQSimGTdfIf0Qjj3SmV2MnBUPErpaO8LoMQefEnV/S7wqVuj0CQyOqqDZ9hqqmVDv6fEa72qq1C3PpYbEfZkF3Q7HyPBE7pCoPHFWQJK5hQ5Blw46TUF9voSIQYlDYK/HMcJEXwXT5PdUlxJfH2lbl51zMG6WibBETinXAjlq8mS2FO1OOHpSGNxHELTCecF1upNr+4CRL5+hsNefJNFev+dcJ3+3FBv+4KLwAymjEadQwn4ypEQZ/4IbTjna4V8Ua9zGzEYwrgvAU1cECw8xTJ7ZAeOnR13+uurZ7FESvNh1M39VX1ppmazyvdHJglYSvADzVW6QaRqcoG/vQFnGeumSlLbGHu5C8zRBYlM0jYZTR8SunZkUZidULOHLYXhmo8mwI/T2wbrNXmJfLJq/TDcxVbcQLlJpvAxnQJB8vCNJd++d61PFpOoDZ5hZ8sQkNCF2jqsqhCJT+am0L4KRaWuaKmxf5o9vPCWAhHvWOiyGMdFfJXgT8v2V2br5Np51l2CBZiWZr5dtEXv0MexP3pAnQ/yoMIxClkYUaonMAwUqiiY3hN7/U4v8EUq3fFqFqOiEgjfwTkvl0mK9TOEir9CG3sHMsyNqvMUsheCkCvC46+NCfd3D54WCpXGmkP6W03Tt7LDh8v7/Dn2HkWM2RbAvZdqA4GkaD9S4XthaWEQ6xSGYFqOEvMuYWUxqLrN5JipQQ4wz5XbIH7q2dghw/W+2gL80/kt7+7XsuVLCJJ3Xp9qZWbHCtB6nh4VufI63FwLc0deru7/VQiVwITyfHcmJG1TtxvlAWnLUcwwbdPNG0THBMqYzL1tJSUO1rytzxQEEEFWPtSnHVPh9sAWPF7XLTMxMIjXWky3sD2fCXQOMzlevH0pbqPtov2CttJ2unjinrYu2wqSxBDZKgET3jkh1IUkjPScfivJVmh6hZmzY0Vd2LszQuSEeEUfgOCDN9SXzZvMiPFqVNU3DhjXQtBtQl3gdIbUZwtFQ/FO7WZ7OMxiBKKOCIDQ+PigHaMEzJLgCuxSoD7v2YJPHDd5qfa2OmvOXKrOW4LrAAMef7AG954mQ5y4oY3ofW9Et711l6Ed4ZDujeNiwSmi1V/Of9Vtk3rBCoiYFu7XFwVrIvcHhEWrx27ntlFcLemK2XRbi0Vc/l1iWgah+Jj5E57CH0x+7imHjlUgCF6Sd2nngawTznbexZzXLtX1MsaRK9Z3THcYKBspB2Zd3f70co9XxtZfGxEqDoKLegUhubDFRRQkwkiT/tqD0fiS8fLJ0vbNZZcyPLhP6YeP2f0I8Rgmmdh96LJiccHXWyFQqdRyLreFqfm7+q7gN6ayXobz2kzIZoJRJJR0lxFGMSLthBqQL3ZHu2mM8r39tpAmkr5aszN+7pzH51ARjLGb/NlG85/N9cqryaw/56gkskThKeFr7/lMSwu6ia+6rGvsJkrHFQO6uHLvWQf5CS9KGRXICkm8kJrXBf/SZU1bBNIwTuTW/+WL8A8+WWVGRY0ZwZmS12EKoNC39bH3/VzS3SNVmGkC/G0dT+ZYeySfuB2Vl1lVpv9SyoR1o75sLOxHsrKf0Jm7tc/mi5QVUwgCVeeGH1+pqr8cnepaJ9CI7Xs2Qvq2NeZ508+1vzJJboDmJPeGwOrdMBy1BVUBiNzs8N9OTSRaAR9oUm1VlUsJnEgBssi/mClj15G3QoxoMS/sH1q4Eh7eVh8IUYJreEdMY5xoP094jtPClgo8E7XyPE/tRkZeywqADisXmoUt7lQoxwsH5dxB7lQe4C2C8u552eCdK4Ke3+OtfT8KuuyEXlmw1s0wGCMkHz5VJkYp2y7VoEGeIdGjeEYSPhoJU+uQtzP6ogeuk/nvNmgwZQ+NOou2EgnD5dg5eenSaP344nuvvOXHbQf81RocNA70dGy4mPudPA7EpTPWxHly0kf0LIptqb7ZdFRKHZVGkCTVhpOxV72OihbQmOSZSnRnNtrUFlX22trpwKizfuxDMZbUfPwr1kb9rczvZnHF0Q9H5ylYJsmHCwvB5AGVyn1Zl9/DRNm4fUGZLEqq1ZEMlyRsT1LKIcHMjvyiSHBB6XPUsxKdaEtuAsE5x0hseSCit9gRjntZyVKtRSLsabVh5rBOfsT2TEmVOQvELNYWUeKMsIgbLQj1odUu3Co53whgFzRLwPAgApnosOrYDpZssRc5AZruAHPPFX9DBMUWtSKKsMYyeLQ3kH9Tm3qZaF8lZcfHfwJB18THn1O3i4VoxpqnLAe81tbvhAV2PF0qWR4dG8mJ0djlRPe6/pfhVVkyYNRVkfA5fN/D0nuWO5N+SEpb+4eOiABoxdSOm7HUl0+xacKf0mWv+1NoTwIOj4xxmgIJMY8SMDiXIP4yq/pKmWA4MUiArpI6srG/HKAA7stIRrFeIIQ+hP+DM8j/4dqDfUc5iIt++xIgabmwaNWDDcYSAwhmOK9OqF1y6uaEY1zJCCyofjwf4N44+I7Dl25t5S/DaiB3s2thsL1slFTzm/h5PS0SRf5NjkRUyRjWvmYnJmswuoXpLO4RFc/UTPOeBGr1uX8+a/XVhXz1YlfjuPZVmGr26SHTixzm0bhmAsK7hODsJl8xbJhwK9CkA8RLNU8KvvFbfhVY1Y5wkpaMRK1nJ2ecn431lYDJRQgNMUmq8qTfpZq53JQ9FYCcqp0vGOT0XjEZ/mty+AccEefi4EZAyndn3IYoG8E6ieGvSQSkpHYPrHtU7R34v6alcYwZnx/YdSsXbC5jHXUiG83VbCRg1fS06TRdcVA01u+TIeaSehbdgV6DF5tCCjq7Vu1y4BEfQg9xGXaOxlLbwrXs9/W+XOc35n0hNrNcxwHSgqwkXL6ljGwZFGoTiHI+Ufufh9jS7Tn3zNLmoxsujzyL96k9G36CAv/u3xgqXwDyT7du4vdTsQeJkzGb/KeVKoA7BF1RcwWvFQKv68BPMmS5dis/we4MaYYhsOOMfHmRBMalMG2xEFWKegropz7PUnBta61ZY34FWI3A4/MyuEVTfS9SaUecfd4lMKqQMMTW9T1zolpfX6l80aqJbpaab4wh9ilvay3pF3qKL8tENbrnhwcXG3OnzVAXBMBaZ39W9tQyF83Dh41ZO6HVc/PfPyq6U139q12Dl7rDY7Cd2xsKX/ABV7EVBzC9Q6/VOxQrlIBZI2QUTMNbSbPZZT0QzHwFFZjpB5ZK+/uYsvRDX1//JoAQ0tWrE3ewlePJvy44pEaQ5qnASaBLXx26SMTVUlf7HEY8QtYB2+pB+C4ojMnvMJ8VyxHHBw/JVm1qrPyBU9dt0HnWyfODslhzJXkCDPmP6QSUgkighNcTOF2Ye9cLkECLy1CrHpWtkGvHvh42AMROVyaT305uJQWC8dRUPoTxLZgAS8HpBRVREPl3ERtTHsoKC//xGp3+A1ITF9PxT13jvxWpxYYcy9I/6yylywkcv5XJ+GmP7eDHJhUasNLCQlgkPC6xSsfV5pq4vPT7zlwOW/qImeYHLPc8R2lDtEVeUNIodyyYZ1PmAGvPXKF+kfLJFHoiMwdQGsh0vhQ6/3Mpj6Bf5mrn3A4dhHECcXulDZv07LU4sJiZ74Gb85LdTE9Frp1jtmaR6AxTOO/Rs9NnUHDSaUBXna1bY9gL7hBNKSLoE9dOdWbP2AAo+QIHYxCKirDiEimHZazmyF2CacscGlvtd9W1aiXd9ewVgwLxmeKv7pDMsQqUHFRP5UOGKR0XDSX1ri0+vLNxpJ+znxr+0N4evPHwfJLvL6fw6kP6LElFI1JfFZ/W5Fv2MR4julgVcJiOyjaOPTzBu+DyWSSS78um/XV2LYP/7nXNdMZJ75HAkftg7EbDS5ictK2aNUW/Kcwd9gzy6YKDx/twwUhtzwBqd6A3wkFHe5mmPS2wwO+8NjmkobA5yWKl955hsTkEldC0bF9JzN+gEuis5dCn5WIQ7b9zZncCm5MKj6orDlwduhorg4wqrAcgwWUHiK7yc2cqVoAWm56uqKFblggf7cDDKofNHUuA4vpk+lbTvEembRa3btt0ldLCzJgbzOT8bSHYNckXar4q0qnTnOAWN0SAw7zn9IskTwv7LcwelAguAjcBdrsEzIwEc3PvdOsA5ewv7TgQ4y9ZGzOypHFbLH2wkzi9itPKSRDi3+1hgj8z3Ta/7bcZbvbdFajT3ktghbYuHtxH+k33V0F85pHvJBQThWyTCY64CT2iDENJAP8b9Nb9spr6j7xgv/ZKywm0ZcJKbKDm9lZALUYGGizbNPNTKTQyaJnu89LVr0pChnpqHNs4xtGFo8jfN4az8xXBdJF/GOkwy1mK2SsKkIxWcFJzWqxgL3qJUQI735+LyERCeUUpDxo63hZZn4La5LJwr1gl8Gi0IdFb4/NIXs74FMHqCt6bMXpaa2tV8bTPfGoVLYu8/EATR9wDZFvwasPxyUMPNM2LPSeLDtxmqaGWdiksGtsmmoFgGQNeZ8ZHwsLTJdjG2WxBB/DpRcEaBsWP3JbAeZqAFqqtCPxxv8/meAYA1VYrtFqB51KBF7+GP/msx1/VHXSF5dcBLmboVbI6yJgIKcIE2+Gtwvg+iBQmvAId3T5GtjoAtlC9/Y5ThvLnZzxygonTYExQ4FPIoFIBeTnbL0XZSUFjdPT2h84RQc/8MY6jN+EDOu+PjX5y9rb9SRONGgh/lOmv4/BhPdX6I7hvhTD2gGtZLNDPJl+va94zffFPqEH/U6UmcDshI1QsQaRhWP2zStDC/nrb4Pe/dtnm+YR8FeoGO4a5JMs+kLHA+xhVJMr224tM7v1h/8m0wX6XH1nMOYRJvEwpLRs7I9J6+4Q3u0gSOFBZ+91CzDVkTI/rCF1c5iPNqDr72y++hM8hgTKcOddMpSAAZLVwAEQzZ9Zj3pjM7NhRTTvC2Ay3Y3d4CZO9KafoVzNVmaiPcOoTIct/4BNAHkGiYwbe7BgRFh0RiBM7vmFfyaldlKrqmZOCYVnBBjwXU6nZFX2QJeZv6edpOSly7F7i1NfjHIzkPpev2d85ZpmVr4TXS0IwmZYBwNM35Hc/DwxilqkNLiI/SD9j1fI9iWikKV3xObtGOfgXcGz/8JewVPgDXkxkk8/tohAc/YX/+ZjNnT0vgD876xJKPo+8kBgFO1E4w8PQFXbwXSBb0e4S3DmWzmNGP4P4qedi3ZJuQvtFa5Gcw1o0ZM1ymMmKIwnGPElUNP+R73xcyPMY6mTNiiRAtuLelgtOnXcZyNkXyd7ikXp0ItIMIgRYrhCowfylgC42HXnMKDDKZyodT6eF5EgCyVO0rABgAuT2UbCxb1kvNrIXfcUdJ3pV870r+nxZQM3UcIJKjLsaqwlgEhHFNNFDOc702FbcwC0aRk+QQ7OgKWgWa6OcBqWlYXT0UD+NRexPvaPT/XoPm6BhM1OYkN8bmPyBC+dEg8+DvA9cP2JZuUQw6Qajaj1RP6w4ExGVohh0x1pLOJcYUR3NM/3AbfVOPxjNmgO76lS9D1xph79pI8egwlWVlyKwRd6iKiPtT2evvoRlKp5VpOBVutpq1k3Ml+OlewRyhQFJrEvsbWY6irShrJhvf8kpSlwHCfy5d+yLqywnPnOlb9mScXANAMYGpfshVRu5l2zniXKPC7ZsCtgBiM1tS6Kvf987pKAbiWr7XDvNSyAzGeJlg6SktEfV+fpdAjMguWWnazTiaVtmZXuo84RM8hbodJql6PtTRBnT1VZN2Iwh/ZxIpsjtVV8i3Xx/rK1u0dTbMv6WRn7CziNenfOpSjiGSiBhVbUbgDFgy4cIzwNTF/loIRw0uuH6TGZcBwRskjgHR2JBUN/GoHfFUmoqjiNPSmYetnznMqGCbV+2ienB2iDukWPZA8TYHkqN+NtjtHa7Zo36C8vq6HYEM1zwOdyTCOVRu/OZXEWbzJsCf+tahwhc5zDtCJxpcLrhx2j3zKEHwcATltL+lYulUFNI+T5n6KSlCwUwnRXvGrVY+W5Yumi0AH+eJDZr1BxoLdfd4LKqOZNdJ3gi2PRrzU7g16+AUT5UymaGzMb1k+2S29UHcsvWx1Vx7jjBee0fjvY38tJWwAzLW6lkkepK1lvAuttxqc99UbPUlKZ1n3Nz7dBYX7NPSsOgii2mRiYse+TXBnKRRgCLJASPEW+WYiP9yAQwfNKYurgNBUT2wN6zoMDo1SMKYAs88UUWaFjteMKP9Q46eFOAW9CYEW94iJixxyvOVV28xxcVF10eGmoqfmdCU2dDdvJVimIxbhXDl3LN4t3LJI6+/pioj8d3LGTWsg5iN+vIRLETW1k76DeQXk1YyQC59c/5l3OR2CGnfetzpIJWkG3qO8tTNNwQ+ndx1libBwVN4g2Jb9hhZKrFQShYssQDXkO4PqEOxy7qNwN6dbISlxedUWLrL6wUCW4L8bvEwB+eSln9VxPF0j/cKa9E5NT2Fshz2dNKAIYfKU2HDoVHMOiiML2+gTYIw/YB4StkcizPIsPPqRgj9m1HwNl2BIeXNMS8X8F27UFo5Cd9VFrAEOJRAzHK5qSGhQ5w3ouvgnmkel1m36RQjOK31ljAW0ZaRtbfYBFrbmlkxcX7nkknSBQpKbsJ8jl2NECqKXdRhB5l6QQULYDWBIUtHVu/xEOsK6MzPC+WlqJOWDM5KzqgqAKjZ5Epp6S5wrNfzspmytTd80ESF0ePbDHGBiqoaMWB7cfkn3uz1iTpdnEvF9YMmB0L97UsDs02YKFbFd0Ecn/17oUwsZKqpErM3oNrf3GRrC5LfinqqhGVSd2xIytTuaUp7tLIVAUB3SNmpSz7QX3euCTpL14q3KJE++UkBellW6I46vtp1LOk2zXxAqwCK3Bom6zeDMCWD6acnpLcSIooNaf63atgE7L36827cNpkg9PLS80ur4pD+dS3WUdU2yFfbMQoTPnFTInxvKFBI11suuuDOpYqccz079Uqn7EupQWfwUvvoNZrOE8NUtQ8fbVcivpnkePwUIbTyQKklhTaT8gpQ3OFvB5kLyexXHbMQ2JotKone7nBFSyYsjdtB9jIC9fqonuQum/W+UEbqEQy+2KyZ1SGYgUf7GnyvW4iDMlioNdS31aQT3ia8fHUccbiNT2s6PrwVti7d0Z081LTRgJ3g9toxB2uedIOP9s2LbtJlGt2/FYZ4lOMaEkf3mnl7QwtRx//I6wR60/JJ9XKaEG2+pqqexzpTavf29E/tA9a45ZrRf5QPQG+TR5VE4AeI0G+x9gUHYVyf9C7pGOCsiZdIq2T8XF2Sy8Jca6i1TUU3RCsykxL7AHLKpZhkDTU6rYE+n7ognXouWCaivZiuKdbRSxDa0eGmK/dX1HnMeeE9IYk7tWw+UNH+y0CKRqvjov1k2gUtcVkMORRjfSsXMS1HqxYt3PEX1wp9S5/2eXTUayppcUc2jtqJm+uCyx/8qYTsV32e3u36l4w8wE70BkIowJXLJLOsQolY70mzfnJ2UjnINDMpo6FN4u9Sog187w13EBv7PIEZW4Fuk12sygW/DJbWbJ/H1J3TYLil20V1yxJNrmDotoFIUE4mqmadREanQzL+ibqTyLc+3aEoAInIMVLnJXw/k5qiVHrbISt2tgLV0x+qWy5euy1SgVegePoxyQ/nav65tvSwJoBTvWOO19njaBiSQgiIKBnl+/j2sP3y/196Frht9dCPGBNQSzJGGyS/DJwr0r02foNFFG7SkTAuqskIgT+HhoIZ/fPvtM4tmpsQNLRLK3FZbVB8Po+MxjDCIQekgl/VJlVZ2HdbeXqfZYi61iVN9t7aCI0nQX00pRpyUDtogZndqyRMeE+zN40hU3AQGCnsPk4Hns8kO4P9IuqePu3LRDCJJo9rdhHp3io04ptCIpt9JbeGEn+YX93cqnSlp6RNVBgwn1FI++BSoY/33HeQeeQk5TOgJrT8PhhRukWRzw2s27kukzI8MVtvydN/TOCdUf/S2YfV+FCfOX7qQyJTsqV5L8gxFaY42HdcqXTbVhpCzpACi/tLuM4LomJoP+HXiy2xSGVgoq/u7AFAUwYFP1cwe+bsktiyugT8KaPkFs15piMzxuFiquEsejUpFr88BzHypIvg4kwBssat+JEqg+sY+PW7ZyOuA6iFKKiZp8DAHBtVEVBJkWm9Tr+JzGB6RAXpfXkj62mJe9b6r58tcF5GcIChQLkAnNpnVQKvZ8WrPr5c9vWdLPS+HdgMUFgCXl3I5VNPK26wiK/R++ftflX6X16NmWSKwBe9W1L17rgD3aBAp04gyfkvH0AETxoHAym1V2Rs/YUfabprpxx3G1HjLGJqtdenufIiTd2hi50j5Lykq5cEFOr2sWf7I7abvgEELfrl+ROQmz4rYAqCZ9zlWCsWOgvULtnUSJPZ+n8oMk1XOEL/yLFO/3NyX2Na125S9DGsj1M4/fgrS5ADB23oCB4F9Zds5IpKH05xh8YyVFismfVMpKr2Klh0hyWQiaE0IoKAhZMk+LHKOygsKiAFONxDkr1cQdHjhN99tFUsYpicpIqPlr3HGnSkR63X/oa4Nuv38jku9Pal5boJBSgBe0bLnMdnGaHiKqebVoHxj7WRXVxxNyHTdOyq6X9k6OSZQ/XUb4GOoGAOSSw6wkCCCTqN4891iEhIni3GAir8z+k1UGiVbfsAoqM/M9Zv6Yg0SqRqbOnd/plt4mXseweRzzmTQmKNcAuObhdhiiQTTZJgdxQqKwvLKxy6bbee6BWw4X9VuwqEZJ5odDfYnk34qcBEEEVlkeLkmiyqECnciZQd85d2UmjQbyolXSWZaeHFenbKBgR8NhD1JFnZ9XnXOw4Bcilv25NSORpJmhewl+bZYCV2qxv0/dAWSfWE6xn94gmCc8VyrYPKoaqCQtLK3WE0lgGGq4e3o/QhXrxrXQS1Xp2b/fvvHsBrZtal8liiHRWKD8RdkmiesaUEnX6u7swVGrLz4BREsh28Jr4m646dNnthk6vi8pShJw+FSF0pB3saXih85Lvfx7WaL1Wq1H4r6HsurhpKLxbTmqFuskIhcIiMd7tdgJhE/qMkx9g0KjiCAlDb78TZv+s4vzk9paIddvn0NmK/kpvb3NkjTzSqhkxIaq3i8y75qi//2dNmrd1Hs4PYUsIiZ9Saw0s5SOISbdOYnuKYnvXtM+IhuEwZpoNcqD3n/3BsrvhOUHr4j4Inztn9n2Piefb27qqDuQweRp9FObGgbWA03MoeUp6v2cxxr2/UYTfbgdevq0jSjU40bHdXInkSBjyi0vWlmAFd1X4mq91UMt16bNYbPPY9dgcNBOWWNdySKSnTYNtXbKWA81liSYraWthtBcFKhqrMwIAuV6fCSF2XT9yDwGxzNDfZFVtmff9il7qypxMiek3LuzsOhomYjK4XsZXLyXsyeDOqHczCSeh0cPsDhwPQn94U0F50XVaD3VOW04aCWoLHX9VTAKuLnRiCqyGeZGP6HhTp403vRnJG26Oij/+Lee+9rwf+JxK6ChFvnjes0DYy7Y5/+frhkHP8j++WvgZwKaNbYtq1nSz+eqM9pWkjMcOGhMsNwCn0cI+jY+3IpDiZI4R+MY5oTFr1Ig6I2HAov1IrL43bJtpMIKU1B3HdhZtRmtRpkgqhatgDRPkWnO3pZkGICWy3yXlwZqLtREZ4D56UruuSCBfYJ63qbT3T1d65IEk3Q7stjALNI8slx4eRAMhmiwZZagn/uiJCTfxmPNLb4o71+i8UGvZWDaDjz0wGXJNcGG1TE0b0rKiYitE6o/ZBxF/sEOL1ZPIrcrqIjSCtstAcS7K+OGpR4x4QxmRmVEZojJ3glvJMUPB28CkgJz0K7YdR25uv7h3iVpQvALdCeXSEjtJzTTZla0ftTylh6FuZZ4EfUKnmUaujGR7Qb7zYuxSkw7Mz+VvqeiHmXkBxFqy+c8bvRpexiBTKBviMNlZ8Maj54sKxszM82IcB4B/aUWPLMfGfMCyfiukWUEE5tR2SQEz2w3sBWn7MbvliDbZJzvlgnhmGB36m7bQbrlKY0x430yUpp8WYxti6l8w2/ii3M456byiCSZODUbn9l3FiLPqY4GsrdC95cDczgVMT4PTh5jr7K6Hh9F3qbkmBsdyXudXdDxaf27nsuK20jWRB/j8FAS7BieQG0razfwW8USSUpQSxR6Pulh7cFhAuMtknWyBk0wehIOIAVEGjfy2lSwKSIZPEnJjM5+PZ4QQfLIDGeKyk38SNjpBIttV4EhWcuXFiQssbyWKkOxSHkN5wu/2kK+NNx7CVcHXKMM+shXowKliGaBvp78MFx9FRfAM7t3h8ld0B6TlI/n8R5j8Z6nMwgNbPl9bnK3AqgfR31gryMQWoofNLU7coczV2tOR8aTNvh+/YGw7pTNh58OjFGxJnIJkhcYaKnActAgYoywKfNtOJFlhspIdFF9K7aRJlY6IAgl+rL6vYww5DNu7stwiIailxPkBkUq4WIb8xwOjzdxz4xA2/0lrSp/SEUahL5m8Hd9bxdsH5dS92zrmyPlSjWJqTYpff+RmxmQALh6XLzdcggQd4gn6lhxDAoS4ylGZrBRpZnw6jQUO5U+TuQ/tgU8MLwDdFfYlGNDigZqt6kTHIMudME4ZPWP9IHO9rjks9re4gkN1s/8VLjCpyFBuhGNT8GairksmXfUPSa7vonj/CGLeAwv32hLPQQSawuNFsgjRzRS2/SmWPsivpJWfidzk7u8yMkNFGgxiybryAlwl2F2WqSzTYWRygOp20y67W2k9KPLNF30CQ6Y/D0plLQlL987F4NLiQA0eul0k0B9q0XJFHc79iEQDnqjdVrTBVIsecNl3uuWWL4Wm8/EwKFtohFU/TEnnkeHwPQerlNbrs6AeFCKC006AcwoKcC3xlSy0o/2p1vQScqcFteMoQlG/LmV4hqcQ13/mx4sVQ6ZCCnwo1VZ2Gl2x9XiUhR+OE1xqJl+d05Tvzh6Xjh/jq2wbhSe5k5RJkw9Xw3eLFUUG3qGZsiZU1m9N/dMBNHc9On7dsUaRzzVIxg1saL9TSAsmeyMWdS8Knwj57jyzoxeoKvF3XEKV/fb3du/2pWtBpwErcfJbpAJOKFIN14AxfuEVwoXGUrsKiX0BP9N2UF2VFISIxuNd5N1zRkrNJCEuDq2QUx/EbYxJUS8MmRBWkJwpXXp0yeVJNQaWDowcsU+FHcK/SdQhkV4+IH0oL49lIdNGYp327KPLvYI1JJcny0tB5jLHABhyzvgNt07uCCuu9atly2V9f6qxtdxOEXHGiHnhJkKy/u7pxH6twYRrte9jjOf0yUm6T2O4NqsC7BJK0PZ3JEtm87KZsw4gkOg5ar96NGi3AAzlTaLQs63wLlaIUHeDuiTex0Rfm1Qv+ZHejerS6PeNCvbSTS5eJ0fGwPTn0Lt3EjprtETsSsAjC6GQt0iTP+qFkD/K5FW/qA2kemjUxfPdV2kdIotW7zhmJpFo9hwAAFXXaky2dfuFoEFase8/x1TLEu9XvMONrLSJBAr17EkPSi18waqViHGa/5Pe2XMnEPrXe/iipPy0YhW06+4UV6pLJlK6lhUiYK3ImOpKkfMEQE06b4HYh+70WEcP1hH8UNKlEvjcZYPG8ZqSiYlAP01XsF4zRjQ3FpaXusb6Uwlmedf0a5Z1acmuN/kci6SP8WBLk2tO435TIL8d1OSHJRd1RwXvd/dvxL9isNJTNOG37jittETFnp1IcTva6ZeLpP1al6bektaGu3HGT9KxU5zcCrZx4AIc5isQSvIiql2ehCyYQ26bffpoL8PNCski2ZOfpKKbA6qjuoCliy9k8DYHyE8Voe15jfK3wHtuEoehxSOvqohNfLPvU68RLhn4YiG/+JA9v/vsUQIsTQomRd3dA5RjeBHMKL5irgvOsjtvMtFt2GLGxm5jYj7+O1YoWheI0giUUrlOdyIHvHfj/J0B/b8qOrOZuOg+pZJQhQUjONaxxfoagYKax0GCfVULCUg2+3rJUh8/c7H2dL7lARR9+FiEATJsOuO1grcMc0I1HuxZNAuTsZ9pU9NbBLzjKdmh8/NSTfqpjj+tMsPbjK9/orKE5bKlFEAFooPgCdRDk2K3Ei2WmYkvAt7WLcP5+Fu+waTmdLam8nI9dvxHskEoz6B5F+rpYHyfZVYdjZIww4l5KUGN0nL/yk+iml8nJUkWHbdnfEia/4sGIyvxX1cXFKu1qz9N2TgztBllw55b4Eqy0OBtZ6vx6kTig95ubsEg4enZoypk/XA407BgNVEgqOQpiOEcjNKmTLHuTgrJvCCNt6mMJQI9i+B/jeJCkVsyYrMK/HKiUPz+H6GsHOuIhL5VB8E1ETCc4wHRhlozs+9v12Um89WBOjQEFy9gCZ3M7R+CkmjD59wIDFD7UnymAIr6b46yyOKR07Bll2zW9HQ4mgz3DL4g09HSuYORYRuJBNDEqIMAkn+Xo0nNA/wqnq1pMUOGJcjPO+UlvgsBiOLitmKWWCEMoD/PSruio2aLET/z6/Aa7uqlzAlvebEu5UREjNX5kBvElxSEXIzM92g/FOvAg9qCbYZAHh2P8BXzmQ/LwiG6I3FFPHXEiTorgO3E4lgC8xDPU7bvsVzv1xMi8HFr6iN/Mb1SSUNZkekePcl23G6gmjQR45N5H1HqWyOUjLIu3B7PDuom6WBS7lP7QpUjQyIkweqsCz/EnBUVLdcSNwTZQ5xa4SSHwtuZtgIXulHimTeV9ah9/grJvB/F+MWLhX26+R1H675xl8fIy5RqQ2TZbs9OO9ctx+RLr6igT0Dafz/kvYxT7QufgpFR8rKXPU33zIjqQhljXlWQsHu7exIjf7r1Pes7fJSfAOrbeg5YmkRdyjeasrf9hqcVeU98czI5W7QigAC7vcTaPlsBQBkfZzgXxxDhDYe30k2uTiLTM+zIomnjFhoIzUWsfIVUdB9a6oLPx+Hocgn1B3t6Bs3iN+45XMvYZsQupJeaedr07qsb4+Cpd5JTH4mbWoRVZEXhTn+tvv/izTdAqQ5a3T57wgUcpltaY/Oahn4kl+UTqQguiTNY9h3Awx+Ur/Ia+3Rklsr+feE1+DLVDEf41g1MGSg0V8tP0dJKmA4oaIsvRkuPcrjfn0G/3QlyMT+/i0M3iWef4PHEaQ2yrdodpa8oF/ipe9DdrcmgDrg4OKQDTlTNVNH8eG6wh0yHdOEXSF49gWVxYaKlhGcRowOoDF7vRQBDKwZQwITOiKVy2tW1mSkX7uXVKuNWhQvuFYQVqj40WNS4JI8NQGmxMr/DS7Qk6OQS8//xgl9HaWWMni8hHAMkjPJifQIYY6gSTTriN2ZxDnxtpQMGCLc0Tmz7OES/GvSzjkbcg6ERGJFXajnERBLg3s3gA6xenM8yt7y5InAqZMEP5hohiG5IgWmRLwjwq4k692bStiJoyhw7eBXBGBqoVX5PbEK3PLcMOtQVYgHEGlLCG8/AtVn/9DJKnClLAMm7aFwrOuwKf0QNMrsbyD6gI2ImDXJ/0zttXCY3gq8traeLOjcPzrxAxx/nWTAXjPmvkkpmzXpCSBUQM6IwUmUNDoQgUtE2lAVDP/88nDTJNryMwp6cxsJ26+nY2kiQGkXES8E04cLz271RatneRFMfrhQ55RKTwoZWyYbBwZMAwY+gyLJA2GnhYmf/jRQZcWGfVHE1R+unbeDinD9jNViURyO1ebRlIUfs8298jOEYYGxlRXRBDtdPmeu0vDC1HawmXy05aAydYiTv2gPCOe/A9KdMzJtiUz4zx6PeBJy3zQOpkhtQJeWjiCdg3QjnP2W8Zu+bJBB7Ww4O0LdsCD5gr3X1kRtA4+ur5w1ago0nnXxho8YuH2n8u9+h/9ti9GU7i458a6SFI856LfwDm6WQSd5Y7TL6xvPAyYIf7FuWkZALGWoRoKRKf3Kkls9FGDWcYyCWCsIcE2pdKzMXIfff2oYrVqt90ziAw6gmckkfsWGoTpSiGnQfT0yBzsRA1+QgtqtkJPnL9cpcqmgk35fsWXrKr6R+0dJt1ZIiEHooNaCjBHq3MDVQ2p2zuPPEg5B6r5z5l8sv+QxLNFGIvxoOaacpPjOQN33gYa+JnIj2EWmcXLohsdG1wLa/m1EG551mPBfLNS3dtHFQJ1yR9bstMk9I0JnwoyNfeDDT9A0ej/mosMNCfmqqUZC/4WMqSl0jb+lcKYjWKF1e0qQ7dQZ1sS5uDdZU9Sezt1ufZZXQuxhEkZitKF1m1gUeidY8hw2WzN2GpMy4JvAkgB/LdXS5vuUccuMF2Y6p4F+VXejMI5stnVMtTe61OFKX6jMIH6tUYCf7RM9kl668S1p1lHvTmkdN/x0VgLxzZqbYmX38i0j7glCfQR2H8xqV158ZlQZAoqFkKOyXLo2oIu/iUB58lnRDlVETIc7GWo9xbheSvAnP8D39uZQoObzqPCmySREbG1zfu0Hr1hWkuwVLJcC83qi/ZH3Gyvob96AJs/++UURl6kikoFtXIdd+2Z+bd0zggJHQa8ASFkj0alQfhcpRUKIoOJkl/6MSxnXl/kZHDlEOFlLQYCdiLd9JNTueiaGat0q+ysEg/jHQsDtOI57pcDJApGZiArzYW+09UuiTMAW/LsI40ECF2UPtcjkelk/Ljo/xFyq8uBHBXhZ9M7/iIRBq2jjfJpHuwr1Tuh/3pzn9yYzEsOqcWEr0OTF4kXjaAggk8ROxKxZZzuCiIa56VpFjmqXAj3PSHqZaMcPICrK4SxUzm/VWdtWF0TcoWquwbaJpo+cGGlemm9W5xlZtpyj4dh8/eA4ghHZz/a95A/rqJqArkZeZrNzPYg/9Be26yhdMn3iSKPi6K/BS6WuR30B5SzG2Qo2GfD1NhrcXe8F7kpJP3f+PiaNfCn9/URvg+6opXhHU54qeLlAcskIqqmigvojpKqhv79LsfATQn2RQCm0l++RCIalkJ3DKc7Pk0/9NgeYmGOYW9wsDE+NY03loTJiDsjq36ZTnmCSuf6LRDWc/UfFGy3y7nGSUCzwOjMVgK0r5KaC9H1bbPpmibiqq4RCGWbbg0//WkvcyUytWs/yU38VyvDe6Om4hzKuxrHypiv+SiHNWSVYmMTy1KgHrj/EaWmZyFtSP5TOwkkrz1qtAG4a1lYeR9ZnP5TG1TDuPuEI8v41da7V9mKRK9rkW3lXFihR208hk7j1qeegmL5qbwxKNJYVV1c6zyS0UYrP8S+2/pUIsMaS/MDBLBARCCA9a4ogu5+h45dcT0lbSkKxqujOSypTYEsjZUkzjmLr0SpUUxZ/bc5lxZjgNR/gBnNVjTgwaqHh18hBa+xLDcRvwJqZ+Wk9/ueEVmL/WwwhnrwzqLos6ZnuPtLV7tHWy36YH0pGJNzfbQqSgNGPcodsDK+fTBVrBw8y+z2aYrjagszKqMdx2d03Y78VJEvGtTb6Du6frrn/uY0yehs+WRhFCXwQ+wn0Bf6YC5UmAWGSXAPa07dmTvjMAfyMt7yBIhtSVcnFEmYCUIgJLHRpf1gDQB/Bp4e5IBNTbruhrTL7Yj7aJ3Raf7/RVLxO2kLuN6b1icELHBwFJQr2VQpPhOjrRXssbQNROYpcjP38ZFtz+NK/lonXOqVUPEJmsn2rUOOm1rWI4J3F8B+qotuwWO0cWwmEMCAfUJImMTLkpQ0n8iHsXAO9ZIfdYifQXS6yOVlk/78psUGbWQ1yTsYwWF29gnNrCEyYLiaStjaDU7ap5ytIGrsC8PRl2haDGDTWki1qegqbuDDYjk6SL2/1hrC2QwSAIKemW3JeQ8vGxSZ19/Wu5VHyjsQmltJbmGQ1WZLWhwy5/0BQWyondPfhYM24Ta3aaydT62QCVfNLWYB/SisFMCnifKQKEru7Z+abhnBPKWB0rXQQ82vuMMlXrsbbl3Uhw39T6uJ/Y+W+Hj3KyGP0gcrj/Je5RMHQgBU6+8z4SdVJFweV/BAqR+zYtjqp81uxPtHd3uIPoTgClWFOS49oQIKCnEie+h6iRRyTCtawgMrEIkIFaqGQc1cRAxLroKsVnIovGj9LKelY4MUiLvvDa70YKkN8x7XyHt17yC8PyQBKYiSYc/ZI9hr8a85lybBmvv6otSD67RVg2IcUDhN8wbY9oiGZJGvMGJAkWZsXuWHfP4NyeoRuqKp7qmbJmmeqRu9L9ugbT6ozKKdoOX45W6ve2MDuOvW0aai5Ar3MI8QhiYeP7wC//AJ3lcuLAusuX34EvJLyvyPzuu5Zq/oxjekHTDVV4hnQ8h+35TdwvGtkxpaJR9Ht9WZDS8M9Wem8PJU/EP7NXSyYPWROWol1VTCWYBht3rYAXV3HdAimc2yguwrjwUH5IZ+SqVoGPIovcG1B1TKW1hbLX5o17W5EOSn42neNv2YXfn9+maM3S5yi6EJZRwAT5Y3YtMXGfjUI3ilVtzdhHBxjZYnI+ksIGoz82Xwg/P6hRKzNKCezWsQG9kTAki7t5baPqD+xvav7AsTcnOLQzdvOaoWuV42EVssCqkUgbbbnMlct/MLXGa8yV9sYHjpejjmnVSk1LNHXqIBrbqqQ2/+7dsuw91sWe+YhXM2JgEwC5m3rHuzUbZnLtBjzwyWW99Rluhd0YRFHktYdK6mNhWf25dupyaBe2IkOE+sKJx/J68u1EIaBZUe87pL9h1T2g+CKEYwLIg3k6wCXjxAf33NoampC4mTRlw6Fw1idmyOiijteZuFgkDeAkP4FUVIY/9e7IQT1oE+VjQlVSNMxK1lNJ5ZGgmkUGq26XDF+OIOnz/2nS+I7slqHjv+kfrACpvvFUHEujuYZ80stTWsNHFpPH+TxuzfeuWdT7GU9R91izSjwwtS2ofCwdX7167sMHXtNdwpHVwpikyFPXwbZkxmKTERcMq79SqQSy8orDJI8a0Vn2/EgHlB5OMgT6eY8/75OCQ712sfAylL7m+HcVw6yIUYAgZ2JtPEYaSa05r+sfcnrC0zJQ3TOo50FJpV6WhxIP55MwopySldsa9jg8uneYuqm8W08tQTVQzrheEI7+BNRpVYNaVYqRPZcWfsjB7DjfK9Ybl9O6AWUDd/pkRe3efPNxd91y8HIhOVxefNvaBhCd3TzY/5llSCOAG1G1H2AXyz3GAd5x+SsQDYXaYjuY8C+dTuiopzrKGk8IfqWO0CVTat9A2Ha05oJpoAjw+9WlbmifYe1FDNAGKsxL7AArKrTxxhcHeT46wTz6yBdvV9iuQkbW692dtHV79/GjA2y6h+Dkd0umSuJOLuEqURW1q5YBReqKPeh+wjeMN37zAhKikBhE8KsUDq8vcZuSUIi+8SHKCJHHFoFh3lUfCJ9K3FBAM8GE4FiwEJsVoZwagCsXSQuVWE9Ng5fXYG5lYe7g7K43611b3ZGIu/VDmvi1UlFlq6pzdJ74N2oiMnwPiqwmwuF5kCv4K0N3/Z3rT61gF1kiCp2SisnOVe7sMqGaILbq1mklPlvKXInQ1MluFO4VQsSGCfB6Rw9YFKrlDXvJ2lMbKaMeOd2y/3rm/mAiWcC1IoTC3idfZX7JdYABvoHW9nVaVf/Xnns3at5Ml4EgP0G+5EMzzqC88FxuX0emD7SqLZvV7zyPxJ3j6270+6nv9Hu1B5Rw5nJKrYwf0zSdP+0grsLAvXjJwZCbFEzZMpJ8k5sdoG4Qc0xVdLVvdxNy5ZEHTxhrJKIppKf7/fueZegpHMvI1lsQA+z+CZh9PTbxT50KosDsSWuGWVMGisjFG+D5w66nzAVGVubtxEwjEhY/mlsQx5fP+6z6XfvIsVkkZqlV3jezRqdDssn5ZzvmpUcTrh8IFcgF5xxLfZKnHDUp6LcBPpfnLpy0+qAYyY6SqQA3RJrTjFJ16OuLDtz83f8gl0MYVNmN9q6CABamMAWqLEGeFMBWf+GcySR76y+qCUSQWFf6yYIUzoDS1P/oaTrCDh/G2DB7Qc2UBFsacj/tnqUnlm6ERm9rJRBaLGX87EFfI9dVLat4HCQ6aOq50IUH8yCbXQsWlXtR+y9S+AGkdHxvYRpPgL2Q3ylWrc7Ar0PBrjJRZP60hiaQk/25eEXDCvONh39L3Flrw1h+QdvD25kCvYc24XX9ENWjBTKhtE3/Ul+6n08BOu2tB5vr8yvvfjazmwI+brrKfgt+OPVxSXRNimDRZi3l3TJ0UCI8R8UJxjWzVQaIQMBwZxip/HA4WnEC9p1SnclWFUcDUuFN2mYlqZ+sLUXsUnG3BEfic0rOtn0EIMHWD2KeG1oskvVyR/c242bRvFbHKrfmuNFF5pewQNE/n38/524+CqKB17A3t8oienh4FMqB8KPVZODQtx6NROUlyevFT8VRSyQAon5v0ORk1lUqvcPQPy649DDISX0NXnj7xXQHDZA86ibyTv+Mqp9Jy5stBDA6vM0iiKXmoO8hQKGSoyq8v1+33MlBmluf0b97W6LkVeuQOAL/8NR8+UqvuGM0R3o57s7bUrTDUIUCyY5kH5XyWlEe0DEqGXMvlmWg1CrZqq1G9fH0W6JTeebwKiF4ccnObb+tHxl2LPGbTEdJW8m7/diNqk3CGpLxtAIoFCLQEGEQlMB5VyKvoOq7CoDs30JCSPfcE8K1dZRrDDMPQlA3ChDr0DGI7ZPUYwJgNrek7GYWhsx25430fFQBgbJ+3klgwKBf+eSOm4T7kTlM0HY45ndxzq5FgaStcDq7Oy0UqYmHg/H1y0XsSFLWCzAJaLGSoTi79lgFGif1I+NvEG6TlbvJ8knYgXEVIELd9mwuwvwRCS5oUs0Fq+Rvn0aLGmIgFqyTeXFpfKljOg0o5IM0Tdr8ynVrwSYELtNvV6tOSpXxKSUolRhjYI+dhtSkyXfhurJt/KO5H1xD7bF5fy64lW0fan3PuM72OkBpc/gzoA3yugyTcX4KTT3WPuDIkgOMqgQ8RhJ2l+BGuqsLbDg/I+amE464fUA77/fBTL+dsRisu2rBXgvQjXNYhTW09wLGeEYzcoWkVMptnL8ZtLMaR2Oq84ZFJPU9PzHaMKEa05qTIoiHolQ3ZjyAP7Pgc385hbawlHyqphoQ4u6WYnYMBZwHjVUnoDqpbmrCyNbq3lSg8yCu625rxWw7tT4/71jFimfPAEAv3Oz4EGzfv4uBkIqkaerkbRubhigAvxrfpXt+xIPT80cvthFYRShUoqjV6J5wIUz9qBDahIsiGga3qQMPI/wIw91ZkQ/Kwo5gA5o1tJWS5zHSAtZLX+3WeLly8YUEmEKcCS+sxF8qTBZ9hwkgY7fIcTmhcHI/Q/e+YjafjH9+lmR4puS7+RIpjz7OQ7iETbnC8Pl8CnwcIz6FRVGRskx+dDbHR4KzGZy/1L7jgYqAeUysFjgAc8Jf7xi4weW4RGkpLbmy2TgLK/WuDaQ0WguzSr+fvxxVioBawWxFB2Xq0QJC3OIri+sya5Muyxbk6uLj0ROXFVAWURZNbH3NDZd/j1LwS8NWPgyQjOtvolz9VvblsYb7rRYxeskH4GUTxH5ml33QR017zBKNTrDUSVAJbJyA/1/3z3p+PWZ4PfTW11UPhUFGSD3B/kDxx93dk9sGvdjZZofZTkN0OYGI2eFSojbrRse5zqkO6TOeYtTs5pNQ3iBYdtIpOYG8OSfhvQ5ahwshabDupQlwOdbJYeEAzzU0S/RYX7TWZJ6lPHtRC5RV08a+B0JVx0KNBXDyqQQR0oVGFFrJu9xg05r4JvRgTeyQuS/5xABC1b29FosvZhZ7t2QFNTM4Aaq8q6NGbZIqtLGWX7UIuhC+F9RY7l5t+EprF7gIrdsDCkRP7eQxNRVCt9AFuhDuM/PTCZCpjVqWGZqaRA/A62e5KouxWpWnuLFK5bnSBpUz6G/Jus8epQfD0wRfwvKKoggvNKYJ5ZPyTOKFVN1BQY2c4f8rdDuXgJnnFWZEXI2PieJWTtX8swaDDtkfuaW4bx48defpwqmwdaXgt8j/EibzQ/M+ycr4eOVo9zmNBoXp7adXAA+E+u+dl6qNpzZiHuSJ3R5TbjAlb3frEr7rpp/ATC40Narasd63qvvfsiz6Fvl39NxvTwCogq15ylvM+R1SmJAHuM5jvNmPwmGOvzy7a38B6LivItMgTwRDP/ZpmksslSlRTNC99wCOmUoF9Pxhdvzd6fUpVwKu0tKs8Zk8vTMpizKelywtYnCMfjjn9vh1anrBqmNFugk5/w42OFZ3UU8n6rVzUq0EkPX0WCIYKo1v4KQ639eqB632ntfflTamD000uK0WM/sFFnj+jWjeLOmiIll270Fu2Pq4yWQxvmVaBH0SkqduytKAy8QjxQyc0wsdETy/bSd7T5hJeWbrPUqr/URxvURqPkHAdvEDw2TgqnRPupFWzdZEIwlOOZhIBsupS6h22BXZBFuUOOGWjzxNL1CuHTqx7u/OEBlO60q2wJOb9tsyoigFiUK9zT/hzU2yKpEDA6oBnx2XXNFzuAvO6Zf8jXGKarp+uYWAOQu6vSZf4laEk27ddEXQyv2SJgTABU5sR3imWPBfE+mlsy5VaINfgxA3j9OBwaaOJen2rohOthVuJ4WJMppVnNFw0k+iu/1pGeHeX6/6Msqwhvh5YsD19Pjx7RQjhjwwZ36yr6s8BO7lRoOpnTqUxGIYD3BEm97oaih0SdzbEiSr0AWTxvmsLWpE4/LIZITaLN/WK5uz/eTIiDo2x+Rg50JSrNjKAJLyFf8EBAdkcTm9iGvXvqSa9ZpFeaJCj3JlCpbLBgaFUAgohHi7Wvx5cIYYtBFo4kgReL5VE2daT03NLZNzIZTwdVRBPLTuDAexprNvw9aTxCQX6BhBLTrq44VPMSxXaOFNsHM7PpkA1R5RA620pRmaPxIeisX9NCVR/Wxt9TYJyhrdbriXBEa1KJq7lf7yF5pJHJvuyYcpQnS43PljOUKBIzv5kvtpzEsBh8Y4uv1uILpqPAMGfb9cktK09Ht4tfftecNNoQY8LQL58eW6Jg4S/p4dib9+FTHZKG+HLxMnbwSYJX8oYlnJTTXnqbYYxIX0Yr62O66ULw1mSo6dVi5eA5UU0ypz35ttNFPQHvUkXlOFTVEVYZ3PvxovA86uP5ARWfS3p0uwLsdybCFTHQ4ghvLNYLjGjkJUmZc8GvU/gTatPpldWDv7sfo4P0m2tzs01NehXOXOXmelPFjChjeFDUBWyku50u5LmsP9evEVNWSryBKUx8WLa7GjXpit5LYpgcZ5kgAz7v/qjSMDgh/Ws9HjQ1a4mklFplqrLIhocDKA2YNP6nCAHaQ3Y59oBUrNU81b7vWFy6Ev1VSdfA8cu5t/+c+b7I80abKAGDE4ngexZFSh6B9qYBMZWVAyx8mc9JYGqMgBZ6q9+XEDl7NXdO+pAMx5l45efsvFximEdWnpFPqRtmmRi5dKJYUXbXDgSukfnXrj9szwZCq01Cia185F7jv1T+Gwejqq/VKAISThJQoQpyp+Yan1ktduUpDbqlc1pSHPPeZ2aJItB4aOAj/KZnvrkzDSwtKQPWcAnnveFSLYPSeX8cZJEN7ZtqS6E/gdV3MC0q/FTiQLpiVvK57g7zLOw57fG1UV1arv0MfCriBbsUO4cL3DZdd0/IJ+KPFgTz+EW/MVGP76bME1fNwl81oHSrvOG0KokOVEfpMWEeODSV99WNCHTBFSKiQ+/1BH9Sb3/SQGvm30zAiL5y+O8oo8oBxGtyCfa2NJKbXmldEH4/ltBqp5pTPr6X+8PrfwfnXuLAJ7Y0fos4edJCJe8hD7qGqYCWYBzNXV8u1d3h8XxB/Gck1X0O6S4yOAA++VvWcFoiiTQ41QNBLoFzVuOPgC1S00rHigg/wVxPipXQAIgst3l4JtFGQWK8AH5TYpFD/I4yRGGCr2kfoqNoNQR/tsB4zDbT07peMzRdvS6rtjCuJOYay6joBVvO386THgH6MPCGVBMBUcG2cFnY2jOUswD6/NBpfIrVJvRtQiBCj7/ZMIiwsDgovONJc6FlCVbB7SftwuCoITYJvGSajk8nntcFTWhge7ksMjv3gI46bZKuxohjtWAFrvCaoynaS9QdXrWZniDyi6p3jTuoLQuQVYn68GVqUrE5wIrVncQ4MRo48l99xh0MZzrmYsYhFtY1ckSDA6lx6UZaR9NRqZwA5G0iyMcg+zzi0+sq0lPPUAv2U10blatgR3SexTrIaxsbk9UrtTSP3wACUrAf8IdgznbzKYCe3nKqaEVk+zH62dAWGHWkPcLicr1db8aWco4RxwQJdxLiKbghwwJT2VSIdLbBciw5nII7LR0AtG6tjdVgHPt0yBew5bRHMK9jKvGeGlUC3zRKNqGAlh7nw9CG4dIJ63v9EJ9kgBkSo29DT56rlUVWIDLzab/lAecqVpYV5bRQY19TBQZchZboWAb+HUM4qqpyiOey86biWFte2FSIjN1E0idZwX6MVvZRgZ1ZAYNUIdq6zoFtsJyeXFcCn+5fCQxXEv4Oejm3Wim16bJpXvwkMUkCP6Q+hIPMNvlWC1bnZFqyqaLEic1yZ4DhXcb++WgK05LCPLrXJtoNpGHwxTQzgRMo2WzMSnLbCf+dOiEYp8+hE/p9FHVub8tryV7dUOPH89d2xepUfX/0Z8YVzNQsl8aEDCpI2xGX0K51jzeQw3VO8L10T8wcWVjU00fBKyfLM9ZLAp7BBsmzjMlenjZbaVI+f7LFfGS8b4niLapoOdUEYzSYwcnfLqVOAXFwV53JOK93X0kunU4Nn/1iCc3Jj8Z4ygm0gyfE3SI9fGcvkIII5KWWeE0AlhLb1cNUOu/cCYfZTkeUyaZ2C0m9NLf8liCDZq/7CY7y+x7IqNC2NZBUxsE+rp92Ie5TmK9sWl2w1UlBg77M9b2sKadIeYC5B7qHYmpGUmGd1qSdlTaPghFs8F98yyNkP6crAQwI2aIVzR8VNBsXyl25BsQIx+SA8F+mD2y331l9xF5sDQbsF4YnmOE5HFKAQ5ZIbXwLYW66Por6Yy3KCftkNipI1c3LrCuaEGTv21Tlqfr7I6WRQfqwUtB1k9LYGPkt1vdIG83J3PhaMIH//7+PBL/pxEUB8F8k4hdBa0XO2JyDahug/VhGiz8cLMSSZsAiGdKl6JzSOrUoqKevHO+jE5sJxZepGplIDYGFpxq6jmKjYFljS+y1rakkDVAl6tqpBu2aOX0fb9ne0zKqcRFLApGtzcOdgxiXzg0YooHzC3fdODEwGIYJuBMmiW3h7TY8x/LPb4YuHCCCxZ5bp9llvR8MJCEC0qANhaU96XVcS8F9z6sl0gmgTRYL4EAsKGW+ryUxhj1FNgJ3AwyoEJod2+QKkat0/NFOr6fQQjXyGtjB08ero5dWZ/gFeSzJ8/eO6YCk62rjzaTUmP7PZ0csOBmG/wXPTMIYR8vhg1OPPJx3cxCGcU/NjOFaIwuk/qfnd5xPA78Pg4RY/y3iIYUpvOPYuKWABWTWa4OisQ9mbIu9WUzz4Ethf4BEjVNDbvZ7LNX7Q1/HGQElarnD+NPcmWn/7/LU72KUows2Tmv7RqvZV7CoKYkUsRH3tHR0r1jzCmfMutwti220PxUoZorNHqHH4UNuTgpAye9k1zC/LX9dvKH5P6BqFC0+P+KDBag2cg7LZBGwufJ4UG/0+fYLJkla92jMAYdhPxOq9C4q1VwgPUsLEcZe/wkzfOyIwlvwj/0m+GmSue3v5SwOrssd12s1VSaziCfIbpiXfWzKjSfGGY0+LH1cDjye3M2c7JTICyqW8CR9OVniN2cf72XcgqnVbLsT6L19qe330Boqw1GgehBSyCJ+3b6AIMXuARjPuuzrJ/Mw7dQsC+Q02lZj5Md+yUKJ3jVVDBcy37LV3h3xTaWdS3tcYBznfnO/7HXEU11d3Ipn5jMn3Y3RJ3PoPtUuzQaO//MgpPHsojSpKiaN+BLUlgsX2ltteMrDxxG2vFxCPK5+ooqZeeh9gxQojivjxwpGKL4I+xUy27ZuYaVpQf1/jtI/MRChmLLnJzbGYA6hcYS8pGjRjyFug9r/+zjx7D1ZvvmYTkQUWCAbrkuxhooPWWjOjLxRZt/cU/7fP4gBDDubnvU32a6SMYnrxnJslF4cuN5jOA7nBrKyWXlJ6CxWd3TWyxQyW7FEy6mWb5IaI/Njl1Ab2krjYY/PZ9W9R02AfCLgjAoZ0VxrGWTOeW7ACtdkh4PtagpWNQcjOntDKtc2CwblxK3CmZibD5DmTUgKJRtH+4WBxCP69wwZVyUvHYkYLNcC5BPa8t30Ss4TE2xN1pzMvewuyEsdcu3wQktQqkq6gYehejaYqPsdvqNcl3oPqee9ml+32reCcHQfeElk5cpxbhhar3T7YGiV7cTpgBf9yqjQPh2mMDxTsl2B7dTzrypUEt/RXNOG2DHFQk9NcMpzVTRHAjyAmajuMnWSf95YKw+Nyuau+7TP795cwFN2SvdFAZJQTkXZpLNnpxL+fzPGncpWGv3MwaYUf8bBe5MRRMlcvFpTTVXJGaArBOYFhE/edF79OXxA1N2TQAUr5OelKZnDZp+kF4hVs4ozfT/xpWOcoYul0+573O6wXY3V2c9GmMTV1nFiRr09xI8CsyejCsijDnZfCfJK4RYY8CkyTdEtG/OGq++FqbePBqYCqkwLmDLRA+MQAo5s/V9LO6uhB9wZSA320j99XLhKhdKwMvk4H9RVImnhQsgFChYvI8lww8mBat+FPFJ0as1jq9jyAjN2YGPt04/fhN4zUj0pDwu7KLgEZ5G4qc3/Ymew+d+UnHeTr8ZLeJUmvQd/kfWdmR6fUN3oWc3p/EJuJxIThA+vg7fpWaJ/KtwZNqRPvKCqMj20lBS/7NWmlcYtuuK0tjnkyACmgUPxix3op7tufYlNW4Q11mwBmiXdYUPu/8ZjHms5d08Lg98qLndfIGuFvw925ISxrYnTuRzLGk1Ma1fqehXaW36VeyHMh6BDiVwuQU7SLkB0x65x7xwSkkjoAhi/H3SbhEiAjf69P2711VU6vh2GyW791WA7ktAwQIeIVIxmm2OOBnygcY83o3fg533dcDt2gIc23GJ7oRAZtCyxq/jiRWfsIczwmYiQMp5rY2v+CHqFhpDSNbxfbnHQUB8m5pr7+FZ0h76gP2h/ovW5vjI73KalOC00kMVLnL8edtvjp98o7btgjAtyoHLLI3cIlb7SnPXuotMQvHGIlC8SgaKP4CNSzrM/aXwfcU62qS+0qPNuxHLhwj1CDYEDoT9TDhV0+uJYkLKI/MvSlntwKtf02uhCW78xTVsuDoZWGXKpcCMflb4far9bLJwlK8L/1YZfnkM4vNgqE5QyQKXAAq6AKLo6dl2LmfTWoH4UPQvj3b2RO8aBVHBg+IyHfaTcg4Zwi6gYZGcaGXiTuXXbuTsUYA7s8ckMLJuVz3c7zynAqjpyIvtfgoUYzjFocWhCoBAID5fG23BjQUV3YFI5FOg+2eOzjQLd2A8CWH/4jDnkxYoakLs2/G0P6+oXK6wD0saJiFsRfsnq0K9sBZxRVcAoyH8LI0TD5HQZFfIAPZ0m3Nzi7YZlQgpr4GA7/lmAn5qiB6QtQVM9qroDOgK8GwRjKEr61FJJ5GkaMj2qYL8sBRduXa5t9tyP1KCoV2UuPTkLQNx9KijwEcMZEGiGs82WkneAukMvcKIlGNLQyYoLNRenDDO2FtvC6LcN2OhP767GY89pHrUbNtRt3PSnhQbYlJmcUh707zAmB1FbAnCUGY/kPvdj5Dpgs4VbqRuHU4rRpDJMFbykubTfe6utR+Zoojjd/enQatEL11s/dJ0UM0TgW7oG2JywAX2ZPlkz321dKS+T4VwoauygnbhLWn6cqdbJTW17nAyAaNoQH1TEWaZFhUqU/VWXkzbjztpsXhEL2g9Nef7xuMn4eD4fnWolHLSEyB3xH1OjCWuHdLv8wTTVY4mfyFnxFQkyz5hzPhG6xyYPmGZ6Xy1KcYpnDMCRwMJ/6rFz0++kpi9truGFNTxunlR26IJdzxnx99M2jLItvuXsUr7mTnYtaWxjutPxnjiPlnL2mpJgH/LpG/JJRm2qCR5ShY6dmMYRwJ6epDai5hYMvG08KyAs87el0xxyBbbE8RhzmDcwvocBJ+rbD8HeegN4S5BcO74KfSPs7o1sB2LAGvEQJTmCqLqbmegv3SCBWJSkrPLv/qSGHQt7Qq0Qf8BzlQ/I9q6z41gtMIt/YBi++bRQDUhCfzF3IKILuwwGBsLWOm8MizifaPagTwn5Gam2Ic4+8gps6aR6HwfuA3ufQItIsOU6xbX0JVZvJ4jgrux9YkIcFUPKZ94fsElxENtgwy2quzKhBxXcxbotfwbyLQAW+ff6PKnaeYIo925VYtDMNb0DcAGvgILVDfPRzH9V0BzoYVOfThCMYOM/8/4+uKLcZn7EFEY9nqTKWPvWULDNRXNdoXpw1oXGS1+n7akFG9QigG9JxAlppynvTW6wwp46trELcwnK0VJGr91nxoKch3efdpYcnNH841h4WHEDsZgeGIZH9lN6whpbNtuqEy82SgbXZ32wGrwQYXZoyC3qptT/n3fS24PTlOZ961nh7LVgg0mGvGX3LI9Vji35H2FJ2u0/ilGg4d2TmCVKud2Iu1lnW+9KilMxmnGx2vcNoYVhUZGnfuy4fi41c4RQl5pEc6KdlwczJjtoBixDeqGO1WwB5X7q0nW5dEWLUvMVkAODb/kAyOqywlkSeVqrPnR1FTQbd/ilotnSegiZXlpND/dKh16yySIUxbvtc6HhmxW8kOB47D3ZAs21otpopAuovoq7CmPSliqju6aC0IHiX4Y9FdqINH/HU4HDDy5J1y+1LR3FaDS0zkLPkmX0yNsOSeGbEQ8xSE4EtS+PAaTi5IIld0j/Lo5aDMh4XQoPvp9BDPsRVupxbUK4hSrbbw0byiQCLqbSdO2x83ZHKD+rwOxT6m10ROQ2B2a75LmsXVSAWFPAlCB82e32e9o8D5NQZCuvKhcHHuyT0HjgGr/toMLOzmOb+pbuLjeSN9WW0do4HWux/qr9fJULl81jUfM4RrM5z5W1l4bBzkG8AWVpv0mG63tvvfgVl00qQG3GqdmTEuen+G4rvNlgQU8dtOfD6zuAxJxhrL73oAsdceO1qw+T9iwOV9oYZpDGoU4bre1ZksM/mImHiNmy6M4cB3hR2rLZT50YI1+RZdtB10xlIP7pTkWWmxlg+5u+pc3y7Ed4zfVOb96Djop3afFYKMKXmJkQ3fCsWARaT54OBNnIDA50fUVjRAKZMewI2VP9/zxyHEKj8uRwz5qbiVWiIBOjj71pWmcB9nulvfFau2uv3oTcOnk8Y/4thDRNBYdoTH19luutFbPgWlv+C5yrSGxsP5yd8DbqQvuGNkqWk4rNKcMFtQaKKxIBTZCbVCyMr8iDqNAGVvmrATOeHS242sKSoLtM1w+5jDQODlDEm/G5RTH+4VR0HHEjS55vjWN2UCnXrZIsG/hhBoyOPCvvr2X4xmDcO4quO/GyvwcPV5bWqkHaMPwnCkrdAxNd+hDBritgpdzvss9EgkmQApANpQeW4P+5cVfbCSTLt74pvsO9ST5Ns3IAtiAi09QzRoMmaaJUvyhwYjzuyBC5USH09ZVDB2E08hP0a6O70JQu/WJHIaDb/J6H6XLZNnRhamu5GRxwErs/wVdS+r9O8Xpoe+y5+9g5ifxqfOkuT//+l2wjZ1kLXv1W1DbMTsyC/uJ0OT0qR3yFAfDlXXOWH+wi+uzT9Jl47KkJBXVibTVtlUDUhwkicFm7WlEcQro6joXFirPaCGi/UOhrfP5v8Ehie8PB5bUVxLGD23F+mmsgmtKBJPtn6XdJQf7Pigq/plcGuun6wg+LNikdMQ4KXwm9u4mkP0umPGNYLyT0RJRz8pW/CTO+F/ZWA9GfbxidazUAZPeAPmsglJGwYkEawZEUlvC25ZlKdFD6JdSbZ05hBHzArAlmqGQptAucPgJ0PmItbHhDHS9NYjumPDxcGBW3yoT+5ndpPXYuUpkEts29OqLYZCkoW9NjIpWuSNO6bgm/NDbCmtjChbfOH9XvPQdakTkaFHYHr7IdzTGUnxAcR6pC8r6iAEghsJcCDdsc0ODFGcRWEfBm7czg/r/bxIpxnLMn/VImf1T5utoNW+JlBsCPrca1nhefqn/ZltMJaRIq3ojjKqvxVsJef/QWyjp/G53fCY2p+xAdDpxUOSW1z3Qtl8TjALJnlnuEDWE96KaN0p1vtmlMTUC5Z4O0OG0cCODEReANZIJ1FtrkJbfgNZbMP92sMeuXqoZQdr3YDe1canEOKphlM/lOPLBrgonSrDKKMm3BfDJ8HdJYSJC+JRjLIkh7xA4czUaHjFivGEoj5IE1MXp66vps7uVcgs0hpb0sJIRU9VLhDJ6WOPWLLi9sZXk4MZtdzSFI0QJ2s/1o1zGxrnjwH7pBYg4Eo5ePjoKgr2LlAP1GiQvO3gB+gVDNqfOQOcYjeJQzQ1r8B35VSPkmxKZ6B7NThAvLfN/a1kD2mbHHOTY6YJ/OadvCPhqoY/9nRl8Na7njzWina6AFvmBONhA3eaXtETx6k2mKasRgkH57cLyK3CEiSwEo+ZW1g3+zDw8sEwmrLwJOfLf84DRuOf32pzQd09cG5wP0tGDWbu0p2lCK1Y+B9Y6JYvXVsAJ2XWSFCy1if7gsjetEQ7r4t4w7W+i1sC4yaf79uk6nCIwEOsLl3n7pwyMvuAc2s8kbD00As333XllzEaF0oq7NYyUzWJfjql5AUyI6TFbfWrDKKYSflrISO9/ZozySvMB6T7vrwfVx0WHIXEGjxXg6kgXkSBqxa93ultAeLB7vw2hF5/fJAxlIdl1RCNx3L621MdowfEUxzsfyk8xMIfNMlUj0zGIiaFROvTd8iaxujXsryRng/r+OwL5s9H53n3dss8F+oTHkhBaWnZuwAQxR3nIRsk4UkwTJpyZNQoop5beZXe2EnQl98wDNJ8C473+JOLOdY+sL7BPvfqR0b25wApQ5tl7MfHluKdfm+6Z4RAatk1gpa147ZnPa2GBBpG6xck4GThsQMyGZKaJ8rXPazubabMhxpDOso0+kJxTADnCVoiMJR3ohrjq5UsT5ZV7BOYztZMo/qKFGomWa5M2hI2wN7o6SvvrIWFDrn5A1Hi9KeYxqpAWlMUeNuxkkOPRhb2uCiWSLEsbREDgWkL2gKI0YLNwixGEGWeI69yv/C8tJnV6oT5s5m0BLXKpichuCgYd89ug/JAGBchvkm/QXIhQVpLOTnafLFKaoPe+MBzOU0M9EwXsowPWNNRj6pA2f6w6EhjyL5EiDsGXl7rYXaQIPVfYleC1WtnrxhNEUshoonKY6Ga7YUozbtKRWto7mpAihdHeuSW+TYVurdNF8wBbYcnOmi03uIZONjcwEmQSpwtoc2GrH0e4jw9moDSmDFXBqbxWA6exNp2h+YEcPliplW6ZFKs8HIPAFTFLiBAOLHUWf8VEo3pFAfcIb8yeHmIS6ogEn4Xc94Mh+aRCZEDJ4ZGEKaavHPHd2vsKLudh6KuTs3mOtVXwSXZFOKUgHHItgl2XV7RcYXMA0v79TDUUeZdWEGviN4OluwrW1y1/pJGyzXUJ0u4WA7FhUcySvVTY6aUGVB6XSZmWPFDUDrG0hR1aOYdy9a5R7evf9GpUeuV4tFSif6/tV2mhXvBcMIUVSTLf65jhUIE0NSxYiOaCWY0ma++hgtvk6kcuDU6EV+OJwZhOOoZrMV+GEYUH/hofTMl9DnxK75J0vY05SXVaAFiffvhGBOAHqYxKkFbvLeIz9euXeqOCFcKtBWfd8szlNzpJ/hOvOaM8krH+JeHM+FxcvfnMwJg+6fyq1BrgmbNeTo50gyvFKyIWG2tdgfrQq/zkfDd23XfOYd2zsb7mf9radCxfg+31RO1/bkLnOgJbe7Yq5Ka6jcBzpjupk5MiYuqn25opHdgnzosba16v/t80ujlM9VGuNzROzqp8pDtL++AE3Prr847LPe8s4wLms7tKA/zkJBvutxSp/DxFkhvfiY6/ZDqI5LYM4PZ9pSJWf7sH4e59J8keA9NDe6dkHdL/qtf69j2BtQaIyN4U0DXPf6S+5Xsho/MzqLDYSUMvJrvbs9s+Z/i3p87bYp4iXYBX4p40dRQqay1/VGKn09lrluxxSbH6Pa3mSiW9rYav66udW22tTz51vSBZNpGzc96SDRQULUg+b7cW/CNDBXPhC3tugDEctZcro0jsgbG6Di6bxTE6itUuX42KdbpHQcQVBdFNY2gbdirNsR1GYbzBEv08u1kL528iGgOypRGQDPPl5qBt8b5BXYCHYSoJ1yDp1F1x36BNV/2M9ay98faiKJ49HCeAZ194ZTOdlng006KbpA8AfT6GflqU5/1ONiglmn2X7AzCDPsHxuJ1BJU90z4LX0pW4DzBkTc46aG4TcmbKLrTumWc3fdiQLVEwtmMO7ChEGyVIqZhKuWPQi8W9Vdbi5ragDqUVFiCEbyjKcrEFjvIdl3JoOeD5O+40gOLQX/Bu3OqwwOCs3NOtTIJdB9WdePQ9CyTb0mgA8mfH50SfWTcgpjVFbC3fZY17AQRrxRtuo0vhsviUiF63ykeBf0/ihhRj7UvsBtglg1JXJUIW2uTzdYFX2V5ahfko0ZxkRluLMzMa1hFs1A1TvkrLhEDSIdctCBWsUNyQUI0+rQe2twXOkPULvEviKD3AtWcgCz/HecM7OrwOf7w1xTgUNYRG28DegRryBYD5olmezz9HMz493LRpOfrYd6/M010Qm1lQ7/uO0wX4pg2Kzqr/lTJp/mnNUiZ7u9GGUdnSmkWjOh9aTnb9kzzcgPCVminU0hnLw40f+L7WVjS32Y0ray6Uq62yeXGY2pKtpZAlVoxbZNL2wOqSc1t+9mBegN/1rSnfJ0gO9KQ03jxi6+qwoLwaBnsOC2r3IDyzwu+GZiaO5OFovl9gsQXAcQcwP3YvCXLhxUVCi4Uf8THWuzJgwzlY7KGCBgazFYX6CTJKmimrnT+IR5oXfiOwrPkdz81uDfKXNeZ8KRTJcBNwQ5t2BAjW+F4Ts3ewtzUB5aq0jBMn2AkGPbpqOXzozMrkqwzQOJn3JUMz6mLbaS61spY4KntsidtCst4QSoB5moYqzFGCwWTK+PNUi6v4hzZ5g2uLqnJtGKLsPue/1ugdeIJ3xo35iuJ1Ltz/WkZSoADZwYfZLTZIG7twe3PIcOlpCNaiKGNIXDhgtFCG/8aRSozp7GCc3pm8KjOVkgUQCKSS/zwsw4dGKbb4l02QT9ZolP0upBxiT0unhDSHdYSVKbo0k8r+xhsap3mYG5m+Qc6XuZp8E/TLoS9BPCpvGkSisVbpG1AbUQTiwknlY81i9PuxavkDgw5tf7SXahwQJZ9eTodJb74HTA+Wt9Pk4V05sxlZpnc9FRe62ihl+g/HmLZuDnf/DOXehaxmlLqy+jNsQBgmuKcvK+SnksaenznrhqSN7zHFUsh3dK/OTZFR+4Ti0HlidcEsw+QRuyqDyDd78nJOPMUCHL+Nw/SMON+Lk9i0kAUzEUSJ2PwB/Rk28FTHE7uTemtA0hKm25Q/9y2UcekaZsY2Nkofrmkmi61itHzZg7aLDT013W2cLd+YfzWgoKfONUq4TmCDbFNrR7tQcF14wTLigRi0ZoYoGmCDEzxwmJ3HmYpxI/3ASvkGP/3QD9yM5np3c7nVuouPpn8egsxDkoBqFZTaRbODnoCsGsq0Te+hnTqFfncZBQjab9Qz2ugRc9GAUy1EkXUOc5OIK5bVUudUsaVi344iqeZZ0lBEp3s9fdruhldd3JN8GzJ9a30xZG/nbXTmkDsznV39WNouaPztBfrvfUtwsTDVD9SjmAeqbA51Vd9pLqa1KR1PYUcVBHkz5wNjHVRF+/aVfbSITo6NSwpLKazxa9mNvmoOypmqhzxqEE/nmkx6mJSs4CrDgqd1UA+VXXVqnHykohivKYUnoeLCm10cEn2AFCIRPm9+TwHKt8sxCP9YM17jh4Dy9Iwac3jvfvi3yhCIROWsriGsUEYKYt2b+6G1DmEMfGAVGTWWha+xvixZ4OcYDj5NXTiL3SDrobJDCzr51cH0+KQVgqbNUFMmrlYjZ0eNWvTPAQHlQP00LH9CsCYsqPuRx0pFEjx7/ovXDvFEw2DyJJmaodQNNKRb6oZgfCLnHFLmvyGqONQ+V2yTo39wsKI9DX8aEZU2yBguBnYeTWEYa6TKtF2pptUQHjOUXyEPL6HwL0nkhOmZ6oYUEU17GJrWX1+oOrDJbVH8vB5vny3KWhjhv4dV0lDqpvpWie31PMohfz6IwrRfWRH+Are1RdT7i+JMw2bKsCPbytT7e07ZxnRA1OSZIoeF9NfkLzZsM2oSsU5C5sgzzsLPoGZgF0H8rzABn9U95qhlylPlNG3lZIdVqFTIvd9ahtSA30KT3jJv2VjRcAtjN4Y3dfkTEP+aO/mnxM//kAYr1ZM48J1J0SLEChbc+mmMxel5WrG1PJOrYr7DZzEMzTc2L8QEuQCgEWn7ZtS/11YpZAe8PPgszOhiTRYsksXl9EUgVfCukGzgIJyBvy5/gL+UwINfD9kAj+HmwL21rrJT+trdu/nHbT47fP3ajLgb8SFKKjpVghBIbq8GhUaaZ2RHjixes7uOS4pAFZ1nVlaeM97b/yHlAmKEuBTZbG8fqoqHqmePH+3A9M3H9a0rbpiyLBqILfDGKUo1oWsTUtGbzqeBFAdHuAQt64Pdis2nVAhPp5KgiGucllesabGW86hh4Kce5g90g2iM+Fr0tw/I00ymKFWjmMWZaXkp1BTc9IATIqse5y9bsjxgcKNaJccRt75DeyN049zoX3BNy6HHQhuVZeEkySTtEmmSrkIYQFuMqoWyoslJW0uyj8KWj2tQtGv3Kw+4gBI+vQDohbi7AbzQEdeV61F/xfgkemTpdSt76Hsh0bDTstAzpKC/DZwEvZ2BNmkIhaXp9DhRaYuPx5auDBJwS9gTA5iO/qVP+8QexnpVcyPkoiCtl4TZq4Y+Q5bcPA6WtNtdLg7vmdw5wXzRAeflBk/pp+gff19+O+3tf76tg9TWTXSFAXWbQHTUf/y6Y2v5Y6VDXTskT/fIw2eBgIEHf8Swk19RyPQcUvfQK/Kjcuvje9q9tUMkr26Iikj9DyRUFosYQM3+ttGnz9ThKFDoHOV7uudn9ABG09CYlTq3GgXreA4qmi0GKINPrsoq/H/PKTfcu/50/93BU+hnWgOb2UNtXmuOuZzSoqYVviLMpqwvzCVaNgpcN9iHXltK7EcjCCQMEqRpmqYW+6+SUQL9VZHkvCO2hy8KSYYchioI2kHwXzLEvAbogCQ8lMr7JGWPCaXnh1fslzPgCoCcqj8ej59pxIsOjDHgV1rpVHw//gq66Vq6eGMcbfhEbyFLEYF8HGU7s6tJD9ASmy4qqnz7BVBSbm2gxDVAxo4h2eytG8B3+oQB4YSwlsEKxSXeRmlyb5675bluy6iubt9MxfAJuSyNhLnWbnK2N2XQPsbQLfemNXwTX5ey1F03CWNcaW3QmFpyQE4Rd7u/axHYI5jdLi/Ya3sxkmZpFc5Iu6Le6PumuiBv6zTvO3p3Q0HwpYbKo/uyK5+th3DsJt/Rvsr+Nzh0N/yLvCJbSWOJk9MEfRk9t0GJJksOgPJmLULJbZaQNvnmFWnuG+dEqSK8EvY4F0hqu3e7X8i4zLKDQA6J7vAIzS50PDnc6cX3pI2Z6hFegWnxICRk3oXdqeKyWe04JNwLIkG05ZMw7JkGFu9N5laTyenWNkXnGe2eS4AFKsX3Fq0f91OWAyyOtQcSlsxx/8+S0B3IkFaqtPxMZrH0SCFjJAd8pCNQaSIikWX2yFdcDzBdfRCkbdCWV75xPJzuwNxU2r/x4GdF1OH6Pcl9SQnfDYGwA0opJMRhbtb6OCYHvtUVzWBtXfKMAWNdmaFcwNMWv+3/5ZIdWNco29h1V08oTyPoM9za4zxUges90r095qbB88G6m8lpJP02pbfP2Z/b/p4AcuWhJuH2+DnQTyUGtD6TIT67vqZBEuFg5Zw7o51rihcUXiaCGxHllJF0O9LnCEkSs9IC170bGUERtzSjNE8VxsfBz6XEDVkCVbgK4rBgypDwl7RGMcmU/vHOdJRhMLcZJzUK9qqHxaIDwnQSvlmUYd25zl8ix2ZSWX+0AIcpfprQ1HAUPWX63VuJncHsiSE7EV3rc9kPX/VDv6jsnrVqi9DtUpq0eV9F/T0Tyv9endvfAdUBKeSnCj2fbOIUEjmRF7T4QO234RXqCKgpMky9rbptOqbFzgCV6ujzBWut+MQDtyZJISotiMn2GqE0A4yJrLNfv+K5nTLsjtSV35MTqTlfFiC8qNnl6WCOkw9OobxZiKOPLEwN46oARrq28JnAQ9csl8vSkdBbYBUUYEC8GV3TZ/1KFcbo7h9wRWiky1CF0djIp3Z4z+XiLlf3GjPWiwKJBoIJRAzS1knKQJa1dgg3uOeI+NE5XmFrCrqrEbBK1fpJ4+OKvj5wyC/fmkpFi2XZuMIxlr1VGXeVONgWp+tPzDJo1xFlw1KOCNXD0xG1FNUaMm9ekimsFQyLzhH1IwfX2+GP1/RokMIQs6cl+X1/qExeeDZvlRkXOMHELcCJe+czmpPt7SLCSppPQDzBsJgBJs7TAXCPK6UbiHJKiI3aAc8QmZtNq6tM+IhQxdOBTNZx7Hg+E6dZs7Sds/tokpZsBNYt2e64zrhIAHfFP6b05c9e59XZAg72I27Us3wQIrSnmY9chBBdOXeBMHoatpjeMmmcCKZVYxdC2GstlfTz/oDqe2OMl9v5xAWKiOJIwj+63u+dVbBaorx0mmRM8r0NZwicMg5dMxi8N+KvMejgxgJjOFdkUjHqXY6KEB2/E3QAiBa4pdlhiVQ3V3tkjcQAOAgwZMXkK70pK5jFDMBJKh1QVeXDa8co2UrBkFrsF64+1uA6jN1qr/11TsIHlgEQZxgNgIMVrTRgj4SiHMcoF4ua6bDEQ+62/7fVaMLq6ngpKt+tX5+KV1V5jM+bX0uUWiY3z0kKpgKDuQBtME9iHiaOpFmqnU0r4WTJ8fZuZ6ZrcF5gpIXy8uH3f5F8xwR+pGDq6BdZeR7mjnZkdpHyqt3z6vhCddvgypDYN/nSVfhkSlUX6pa1rUXupiMZIgPZf1j1IiBw2W0YSqMnbmmxFpcuGEl2D1g95SymeG/srDvKrsXFWCUxxxC4SOyQRNUMaab5OtesbMRtk+wLDUBL8f93aQMJ7GMqWBEZIAV+CsmNXn1ZA61aT7njY8fUq/P5WlfHR2IJT5cIRbh7lXRm3C+1AKev7RoGjdwW8vxHMpW6v53RZ/53IVvVgRyEql1FmmdyoVNXoJeU9uQYtYW1gkT/wahsHt5ARfMhfqhTwCHw/fPGPoKLMg5Bfv339kke4sSD32t96kvB5d6230AGsV7EV+9n3gWoh196Lek2F4fVaQd9L9cwS3ypvD8xWxfgzOJCXWA4gZGHBRsFX7RAlZ59ZYUpEwKtUpvwZHVq5OJMskGk02ixaMrqk1FnQn7588DYgWUOvIvaqBZTyQzo47SBs8NYBNEN2cpoxhPrU+V4ir+YsaoT7LAKTGQQIHB71ps9FOadRqYVASSnK5N0cGUfpWqPjXP7UYesojw2PnGmRnoxlplcv7cWH4PTpgO3aG9YRqD3RG7foem24e6aLpNjl2TBek7Hr3IP/nZw75Eo0rfPMTPT5uWHqbVmH/K/s6+sEldH22ZajeKvkxcubCjulXFdlVbKea1DxV12uxlZvkIfkAxcHgZjvH8bTKpGktU/qhR0P6E58Q82CF59PnlwCp0VV8AtT9Z/il+H5GfwTJYD8zH+L/pMSSZMa5ksPL3pAclyHjSQ0NjwbWc0bjKgAAQ7gp0vxLxfb2wgMrLi7GtE6qXt4Y31fQ9Vf2ffrxXI+f8/uVk9+3d28Po3QwbfHP8VOQ0tJAsUQn6E4J6mFoLNz6+6r7XuWjlq9nGsONtomGCa/92uhJfjBRCT4pc/9kjA2nS2YiB4n6mOhx2QkUFSYZL2dubo3Ah2/nPjFi4zDD6oCqUh9LTzFttyfMKLYvfDlaAMboR2oL6Na1zagtBvesLmMwi3FmM3RJtTPmuA9rkV7AcfVsRXpXnndCtOgPCyCdrpCdxk8PKZlN6mUDqQAMLHximReKFKrrOopl3GlAf3nSuoqj9lqdlQebWKyQsrrTwtgujLFsrh3K6WVKDlRmrjhKRNgVyOz6CI/Ot2GVWUz0g2w09JwXwUo5JVjMnhrf/01tROXMEFqaWc/H3hwyytePT0GV4rLFkb4OIc+OA2lJxOglCTwOsX2gjeHA4O8fQJDevyxoBsrSTSFefdOaqLGS8n0/3CfNYfTDfRYCQ5ww8EYr8MNXoWRtDrqOs/68ntbN1QIaJ5L8wby3jyld5FqJOkbw2umWoj5Cb6alILhWP4XS1IXrUAElhaFASz+IC6HjK/Nx0CeKIOF3T5g+wMZm6ej2NgW9MzyB5Mj+xG/yVpJs18Inv0udc4uiRkbpkCBT5w55GgF19liWMvyVF4g5yH8Li635KzOAZTdFETfGe+gs2hR3rJ8wjT+CA7YiXCit1X8AX7hfAXoV0q9MaOxrJ0hDfqEviVAMH/Fj5ePwyMjqtsOW6X0+wNTzzxHe4pNkb4ldkzFtCZElgm3KunkYJiqbqmQcbiSTPOgk89Q77a76BOK7yKyZ+xOdUHKPj/A8Kt86gNDpYdO6vSn56RHHg4nTPRJbxc269FQ9SjJJlz5L7dzUC/sg98h7Z23lIjqiKXY53N9S5Yz7gDm45tat6gf5xUsTbZ2JPN7c7GGn/pAFVCqFsqwynFBA3q1sA7NczHBjKE1bMNlVtoq/9qj/9R+0AdeycuHmXbxac6QcoVMtaxLYreFMIj4kAs3ggfn2JCyziwuEQ5v22y/5EnlMLZ1ERq0/PQlJq744g/FoNKtvBWHTPfN88dusxjNctS9GOtQqKFV8qNGWwsAuOItivwNG3A2AMj2pS6MtNAg8A8oCPzsWjJBw6HDn4DekhdTkGSCU61OGr29gllktOjbmnwnQCeDj7GvFF/Y9a12HdyVf1aVFhOPnHlMqZHqtyM0+WsIuU056/gioDGq8T+0rdge6t0MxTHHus0wzRDxT+7CmSb2NcJ/GpqC4jGtUzkhDAnC+7YVIi9ZBdgoQDx0WWvd6RBF4RNyd4Mi0sbcP+RGYJq9LIeFztDcjtcg7mJ4tVDfq7A0DKsKcAzLJsglDf6D4VWjNo5HS0fmZsU0p6RJ9K6Q0f3GN7zsiBeLvROZ3yozerESImtSdImk2OTSQCTRPfViUFryZIvHRk0TUSUSXF2AIFs0izrpQBcBMeG5AN06wDZTpT9dGtnv0L3ccfPU2PHQ+x49EozYKs7hrFLPEo34kkc+lvfclPiGyJfklOZSxtCaEoMTJPbRaouhzg8IZeQYvJUL2zOSKjQS19EvNKOq+MuiUTVFNFKOlVU0VXsU/xNiVhzawx7ImwCOv+Kx+WLTAeJkll3MC/nQdKwPs2MTbpwbWeoRBg7SoQLLIFZE7RPCqvkVQTaQC8NFEalvpgznE03UeQf40FzVYyxMhDUd/7F9fmTinRlEnucAiVLtD8iDwX3k54tOqQ0/Ox3t5Ne2rk9VVpixw0Ko9i4DMC3zAXrKeHE/evbhyzmaEePpXxRIEuk77dVpWk7mtcmigB+r+hOeL8pmsplK/qgazYyQhhNuzMco9dmEa1SqH5WO+jA441vASkR8WsGk34l5WhADdUvqWG6tOW7z02o64hIqHV0hyLI4RU99KoOB1W1ai6xms5n16w/QVQ6UvP0xnynj8wIu8VUA8+yzFlGnfuf8QeBpoZg4uEh5e2pO0WZ4486tstp21u4MszwK6KEkxOGpfC3QfHKcZHo6A+JRtzbZ8j+UeHeKrz1/qsdZ++D78GYDkxO3Ybr+LWUADSU5NpDz4YIYEvVkNIWAQ+hduSw7kqW0jw6VCPycjWC1J8RPXxEClsj3f3wY82JYmnndfNaa6m74Vh+MEmrtOK8xxcNr+zCtukVCTl6D40UQueAbY8puWicWosVWa2glNFr2Pc+akrDaT966wLwkQ88VtdsTP9eBP88Hs93bV/yyVXcBTXOfP334hrzxNOpDi3tmi9GtWVT3A0NaLB4xUS6cZDCGRjJu5o253FRmZBJnrVWBB4WbFkR6QPcrimzqNpBjk34SxiCf1+ac4bAqrt+aBP4IGRy+suQ+ohB1HUm0oMrU3CM7AFJYpzOfP++LbhzSuJrMI/X/cQgQRncH5MtLRPbsQxwWHMk5zUigJzifKIC2z3dHrW5u20FLtXWzImyEcyf5YWnOB3CaRokPKzqCPpu12F05wG80+YVgaI3UVcluo+KETCpgLVmnTwIltmeX/ZglwFT41AfZcz9ILB3ZsOMHfDG/lbZLDnnHcU72Bwx/qADPzhtypEapoKkXMEfsSfjKP9eNgNseQsx/i5PZ8OJE4eE5aPr6nfuGiAWpW02aGrDPx/d9GecjRFgWmPCq8o+d4GdD+q4N6+Ju6zYV0k8CKzS85H9EJr9LNe1GIhq9HOvaeGwONBXQOdTKPtec9dmUTC/rV3eu3dwIWRFGeVkrBGLA8WkrDUM00tZJK/khzLfAO9VtCorI1NoYw/Jw90G0wnwBT+ShbwlOyMzQdtSzi6q0VNjLbTBjPiV1NX5oOh20hgB3eTX5NDGsBA8hNkiNdTjcBACWDtrbmy7hRgirH1i2qvQyLfVUoZMOvGKVzsk+R5AmySO70Mn9k00kI0gjgMgEgKrfhNGUgywo5Faoso3pDizEN3a2sXLfs6TrBMcrOIbwQqDR6cUpTB9iwX6SuxIn0KBxdBKe/7M93194kU0fuYzIICXePqozpNoisQycm5CrkyC5AVNBnP33290zgXRYGgD+ePbQjTDnMZYl+aVCx6AA7GcETf4/T9bwxBFzctFsQbSFIxXfQ7Ygz51jmSy603+klF3bqXNRVmnjqlvPFbgfWpKKnp05rxrrrGCX0MB4ajGmvtbh3wFPj3M6f6Q3Ar9oVIPUXwStzFjqPubWhOUNXPT5UNT4GvGqgy/6i+JOMfKusnoc76JDP/HWNy5NB/Xses8HyB1edOfKZIG/qhNFdUEKZeFcuLZvxl/SZVPr0mE+P0Gd0RI7xIS2F7cfVwYX9uq+ms38lBYVLazCbgsToQpAk0qLUDRneokgt0DXqhD1Lla2gQxztMhuqQVyLMuqnzs0tAHNNAKcjmmIe0CfEJAuttLADCxEZE8hnMCxKEgWrwZ+VLFfIOkAI9YvWbnZuQWRGmCWbE9MkRM+89aCYMsP+KmfN/sPwPma6byrYZcayGq6AWITg1zfASVCi3jQveNMsjodRTebpx3SSPlyJIjGH+hAKNI4YCu8pW0tsobxjyCzATeBGzI72T0jFuV/Zh3xLWSb+mP5HWGat/Yqf53MnTw0NfVbDs2sV4CWyvW7npI1XIAQzrnNx6niyU3YOhKAeYa8r3dZjFEnts4lX07kE9suDmRouyQCg3d5/gJVyi8T+PEDnhg064+YJzVZEecClYJ7US17VaTE5GIlIhmlbZrEip3WDLAyvcOogAqOK1ljc38LzBRMSpXr8aHiMwdv7XryGZ4Dp61qd/aNqXFRS+0762Qh31jmIRgqWnS3RKOL06/bvaIYYvbLRjr4R4T8kAMhtNOrmotsi0Uogpf2xvuXfbqaXG/FYBTdNbDZ98yAV9gmOHfzIGnTeQx+IG4pTmV3MMdsvxOwThdVlJK5UI288MxtKt2iD3tAcw0zDC2t1LTchWJnG7Sj2YtoCCTUEnviAgOpGmLvS5idMuPKFPhJSW1IW9R/rts0X8baLzL2QvTM81jHViucl8b7q1YpKIUlBRM6PRBrP2yOoTxLfZrtA7VVN9vqm6hG3Mp9nzu7iSjkNALQuqhTi5poGJQsC8mifrI0qjDCgyDQXc/LVIrpJYaxzAmzP7WGU6lq04PUuR4jqkPysFaCvqaO+q/7l/lkr+IWPYQPLBJZ2xT45a+z/apTRjj6ok+fRIyE82RZZ00U/lIVF1gt4spwpbgvfm3oxoCTX/W1g1lT6ofIVd37FSqTM61evABqJwqWTxNM6yOUzbejxC7TFPlGy0tS4fvaDFQB9p4Gj0ZoSQ2Lefoq9DWwEWwXX2TA9uwsBk/nUxDOblBjxmj/L0QbvZXnuVZ+4xC7WItvq2VG1Rhmbf6/ndS8teRtuopGfd+Nyq9NzhQmg0bUI2g1CgPeDi7bO6LYmNTKkJ9O82Dkv3ooJV4Cl+IOsMzIjFek0s368ZAE4tDB/B1EDxXglYOXbltm/mxVunEY1vSNbxMgvhlAGOhivJmQvfLjoIKhQUTzv9vzY3vdBA/1gnK3HHv2bIRQw04JSrhcleS8bpjgEqAlIAR2bQWZ3LpGsxEyFFlRNBeMANimQn8JsrzjFnczq+wpb0tgJYOnNVzyL03qKzfh4pooL9ir2udHTp66lp+cw/mork8wQMw6gNmB9IutCqgv0wCLxrAik0O+3XoQ4oW5QumqbFuQ2qlAXY8Y7gYev0GCX7B9K9bga+7N7d12i517y7x+KBJ9qn6AVYE3PpiV00Znts0X2c2+VpxM/IoUGhFUhI3ZAVp+IqwxC/u48/+48M88F9HAQIosJ/lZ6o2YRnd5hy5FDcm+HatsUUZhZwE1z+KwVhWmUS+AQJAlGJD5W+52dXxX6Xwq7b1QCzOGmVm5RalYwmKjZ/X5mCe/qPi4kGqkWl/u2MdT7S7sYEyVxJRxLOs1Kp8dhGnTpKD32z5mv1QArreKyOXfrxJvt2wd6Np+XZXaqAgql4rLsvxGPpeu8+qBpsIbBaDy3pnhgGlzQYyDgB+2IZ2ekGdD+kqgzc0OU1gFG/dnL4LMjxCOljhhS+TAOA9l5ZdLfpjK3MsBXi5FV/d5l2CLAm2abXJJCsgRikZSu051wILZs28ptYTI/ZEqiAPUbv6vPTuz/781XUlMOQ/5rEPEDqqdcAd+/zczf+KM/xAgFcIgDxZ15ba6iktb5bHdCmljkFzp/iUZfFEbohkYxFpoEOpGKJ7vFEbpqToq0oRjYilUDlKTIRjtvNqYVQDQgrD0faInZpeYm4PFQVUp3OI6bdUtKdHqMVZBODkrQ9q4CWWeTcbQjG4ByBEzKgcJqDsCuQFFSODZmsmfvScovD6ZkFrMM8+DqAb+0HfUhprqdYdU712DZAF3v0FAG8XF721I4vcN4Yz9DvThf/329dj/A0pzv4AkWpRKJQNJekbKNTGDLeWkiJYPm9xYBbs3pid386xUOBN2G4RCx8B3b0DLF3UjWkneZsmoMHDhpRhacJhcvYy6X224QYaDRU1x6Q7cBzI7a5O7WxMmL0BvAP19HYU9njeYODRB2DlxM70yxm3oCGXgJn7smGrYRRY7AecexUIFbU3M1lYlrdXbXfOz4qkEWA/JGMOQoH9i03n3HXU3E7cPo3EO2WTub4nOssmdm9pMUsfL0Bt6Z02y47FC7+j1sjIo7Km0annbqgpQxbItwA0AIb6iooh1NT3h3AUipNSxSnmahC5KGg6GMlTHJJS+iS9XV0J6uNINYWNUxjazThla6YEn34/j5Uuy6frTJL2mGK334q/HkD5NRIUm9w5vff9Z5jozOqJ+DMI3FTjwXqQUy9+Si4WEeJZZERWT7UJkdxCPT/Lz7tNRto6oBZsvMayXP53HCScgnNWa4Ufqa3DOsL2nN8cgQutHNqZFfNbjmTXSdwKP3xKp/kHbLIut5LGFE+Bek3nXksf9/Lf1j3vohk8XCwX6LkS0s1gjSh7bZ+hKcioC3XQGVjflcY3PjEee9dk6dtWsW7xlWMaeQUkGR9aCJ6Wv1HrO8iW9OONAS53kyzapqZB/YWkV9aqm0p/XcsZOWCLRivJ26p4FpgXt/KpChaIiJnLRMhYCZ7pYBWJOqoV+AIJZP/FbcXerud7HDa1tkmXGFnBaPsNCP6Y8v8QpzmN95TKKgp9dKujNvd26Cw5jPkdUf4wpLdn+0U8l8xOGTCHIC/PJQQdEEVC7Q8wQU9LlEOPMuw8x6IsBGf04BJxgcOFBGNah7VD9x9aDN3RhPekNF3tajp4bksg5sMx8fnBmqEch+Xu1REyIy+CzPJ8dF5ocTZSkODOBxEmHs6Qe/C8LWyFbMWvsI07aS8mkkkXohhyr1Z3iElCxDM/phuMNKiwf8UrZrAzaAh+iSUejbmESJkzSroys5LfM+LZUWJ8MpiIaV3KiXyeF6XcyaqA19TnfRZ6IoSYw0SpDY7weeIL+GyGfP5GMzsYGx2/6YKuLIZcgFn2x+Fm4ty2vnjAkGF5oIkKMVaEL7oGGV6h/x1AA+qMrfdFX/BbT3VtQ8ivVWspehplrMPDiU3Dk4wqPkQDzkuO64H5fVYPiClNCsl+kK3nob2NImxcZTGhtPcGO98dQLwrny82ilJg4uKhOeaDJC6EPVpEga7rSmqiDoxs0VKEEyfiqlKevEBod1D3pnhj0eAFjzt/4X8LGyEfgdjpFnfP6ArSUhP/4UCZ3n3zbPEjhexAdFe9n/XYSfw6oJInf1MmFIMuEcxiBvzG92+6Sl1S0iXGZUSxFZDkpcFaYcMDDEbnyVyYJdUZYxffW5s9kazfVGcqtcQk4bUpdPJAFPxwGFwPP914Pb9sZ1dIAklQwJ0iQda5JEnSa7BCo0G80+I26UGjc4umIsDHQfH2z/ztBn3bY1EjXSeEB6MFUBRvOjKGlcEeqFrsVSNcT2SeGflQXT+QLyEjD5HSNYsCNQFnhDF4CDS/WK13Y5exN1rGamNTIugsNzfDS6VcUvP4ynLqlCBhacCWIKsFZ3eVGVEZ+mR/dTUyQjif6gAeNW/fW2LZqvcwFrRMdmzDJFlWjFMXkx5X2ASjH3VzSFaqz8eS5TovH5Hs0mLcYDFCJ6+3MjlMwcPoKNdAbDJoV6MZ2FPuM2ZtlvRjSDZfLsFGkszZXfzwLxgbnU0IgYYvfV+dqkbc8Bkayvw+rUJntI0mFQizOG+PzDXi3gbTm8GDSdZAk3H7Cz0TZ/Oz9DWNRQGdted9h8ZaJAP3P37og1z/CHOGYh9an8sfaYZ7T158W8tjrqbEsRo7b/eAv7NQY2cWvsfHNSa0q5VHqMyIoK3D19IcW5BkFqA9GttCUWIaul78YzFWznJeRj4cCyAmJooNk1NLfGkhbxhLAG/mlZHVDTSx6H2gQGdVxiEOhx04IkLc7zuPJPEz/GH9pO93J2JKfdEuJmgUaqSfym+XJUqBV6Or7q4FVGLZ9fuuNZ2TUQVA83EZomCzmWzgsssO5i8TUtFB2tHpfABZri77zD7sxzoyyXWQmE1fUi56xTAGCLdKIrFYxYGmplG9KNa3jukBpnSn0MUJSBJZcwOhExHxm01PVO71WY+/2qedrOJA2LtPGFU/QqpiXIP5U5nAkPnRYrkXr6LbUHoSINDKRCNseIHcN13sDfqDTxHdjkyZH8QVb6VlUSs+eQbnw+VuCYKSXuw6Bf+cYR2UDpzDts7mFa1EDiDcgxSsvxrAyijBM1agzsr/vqJoBndJL8vs6aCkY48V0faYHih3Drc16yGDZM6DvLrT0MW1PUklXHmFtfO1RGbLdieJnEq953m9+d6zs8aDh08T4UnW35O1+ifbf0u+KoEDRfno0su2ygJsI9BJ1dKwdwbHjU7zilO8PcRcxq07ZpS+nhI3L+ScpaBhkt1qIVLOEWV+pVN/x3kdHPoKDP0bhZ5f+lDD2oXWcB3w9ukkPGl5Al5tym9Lo/+53mYQM+s9Bs2dhSVEhcoOFOckwUst+tFIkKADuuTzK8tH5jw7ukL8XxvRBaud/fz+LlLD4REprSMzE1O7haK6TKNG9eTl++O6bpU6RlVSUunCfGK8+F2zK/4y3rXgKLXFkZnvP0urHcVPI4k6KUVb/iVZ0DMVe1xEz+5Ixu6MLUl2sXRY4Y/FLwDZN3GdYOql6Ypxl0auLOs+wAw26MpD55H54k6ny5griwmJFkLD18HesGsmpw2X5S7AWQpuik2N+vAOb6l7KteEGWIh0tPCQoPds8wDX58xGOawsnSIsHB92egDblC7209ox1JYyim9TwryrnpALMvxQP8HfP0HHdCcZaG00+pPcrW/y0yXymB8Z587KqWxZtcfPzetNDZTKja8oEo3f4zzvvJeJkPJjabCapUbh4HEGk1RZfp0tbFrk7Jm2uK4EDjwlRMlVikccoetGmZbgUEOiI1vy7PcKKjkSNZeqMeD6dCsvnSZIQixQ6aKXv3/HUcjcsoqzBa/SSOdcOG5fv32PdAKFsq1qoTCkH0mhmSzJCTu+UPKzZL9ioUzXyYEIsTb8RKSW4ZpByTuXPVcgFOE1NxpRvaFckGrh0LOl9aG86/iM7JKg5cAQ0vMUVmj7fxnP+cC7lXROcH+NghzBXmy7pVfjth16Ceegn7zmhp73KbCAF28dN0jv4W4PuEWF/AXqGU4XDWjZY0Bxwe6+SKUnXKvGHN0iAr8us0nRKlcHyOaXPdqpzAJvyXOGUA9CDhOCNDNbMI8B8hKRboXvKdkgSAQwKLD75Zmqeb/aqrOiavknZPHNXg0arbsdLDcDx0is8FQXeiueu3gLfw+lLhkMGKGQ+KHr7ATw0TNjhuCs5Nz3BpETgZQhr6UV4zIABy7dmadJBANxNTzd3B+plAA5wT64K09KkfzHeKORaeTp6/eoNwLS+4bRM5O/36RueOUSCBNSkzN8bXx1SW4ciWJ0nFT4Gbxi/OZNVvrL1cmN95B8oFH9OH4s65LRLnkPL3f+aY1bzK7scKhHFM4arxuvgtVetWZgQswTclj1DxSWf1dYs9nkx281deqEZdOJClzp6SIiEKK085ChHM2gb6VaNTTKyw8hIUOcDJ1ipEmpSriQoHlu3btYBpTc9588lzgqRIH+QYqFmoSXU6uqzXjp4bOwM75KqmLLtQX2210avY5axHp2B9KpcgPVOtjJCbi6p7vwytIToniW51EQBDpkbc1ESje0ou9F7tVuDPbsdd4vgU4HfPArry1kgv+/YJ2C/BgLkOF8f7HnLPPa9jSydpVnPPjuC3HCddE6w1Xhz2TtGB6QPElG9od3+DjCE2NgnQB+XsOlZblX+UDXdxQrZuOiCMpLmPAbK2sBKJlX+6wlbwrodRtpvWuqEayRrW/bckcdN3xs8hs2D6qIHZK7QN1e40uEpepNgRoBA9CimoKWBXasC1+B8yT1ezHYt7CZCQ4eQBbztHJd6wuZOPPbC2UruagT6fvuSRIRCTI2fln7GJHjqVlfr3kXR9Nsw3KLxR4hou6imunL29SrdBq1nDOZU5xm5qVDaSLjn4Uf0CC1XrESp2jvV55owdWRxefYt9WirjKKYzpNAOm3WTXfv2eMaGN53ojoBwK47V9OdSNpUEZbuBCOurbevx9XY+7Hx3RZaHxa/oRtwKSDHVEsNAuZ3a8lqCHDBFBjipoYlAhmM12RXNwcXP/yiquKH2Sz63iALt73g8ZEXkchzHN1ojudoBfvKs5UFuIlJB7qbOpQ6vkokW22CmtdpbBgNeBJkrI7fBSqcEkmabAjuRunR/cwLliGLQ7VaYSD7l3MrZ5LTZbQx2l4eHzD2YP9UazWK/gdm3cWwK3cCdly35jJNfKVyaSc2h+IVIu0hV9XUc7o96256hl3uj/Sy6kcfh7Q/G7aEE5vdF1NW57YPGyaZDv609ZctXHhEUeJ8fd2eR7SLapQ9YeeA94j+yZV6+8Bw0V1SRnx3wzsbMDkkptCM46567z/74eCfM94LHOyu+5Kslf0ZzJQDeFb0JJQbNkkGQca06VBzn3qUCgeVW0aWM+6gUdTFkdxeSn2fxwzrvrJT3R4JzMD+04fmFx+IDn1nQay54Bu+jEMcyCyQ6BDfcDy8UyaXmqoWz46lSwbPOCRVOkFy1k8dEGTcNuEMOrd1K5I7GCmToU9qczXfedxNbwLShA+Z+lJD/5dMZ77P8JLxNMNEK4ypWCeJCz3OtZc2l/p8MEnW+GUqoEgmgUOiJokdURp4r9juJ2/Zi6EprqsDgP2yd8iOkoDVJWgsnWNOc1CgacGWD6T72sK63QFbjl2guPRPdGpRhV2ktKwqrOlLe/QwWmR/LM3EPZkzOqfol+jdfe1WYm6LNEkQ4jQhVmuMtSHn0M2shaSLzvXL9DP29+mjfEXpTfDy6cHdm0e5+kiCxrrUEuRxDVqt5DkNsii67UdmjytB8oeoPHK++jXQB7Czs2SSel1QNKRofpLLc0XrIKASEDKJeS1jloZ3MIg6PgrsQjCOoK4+EOD87UDbIzOQ8UnJd4qraowXZe1E3QCRWwuNNHdNgEJKUioXNZnD+a/wPHcIbaNcpZiUduyXnMY8f4inILGRWff0UIKKdC+rns2+O00z5W199urj2HfC8U9sumKoKMxc9YuT8hbi4z3F3H3PbCI+0M+wnpAVDw2VLplKU+333P6uRdhgSsfIQHaGkCk49t8s8dIGmWfjHk5DP+UVS5iGlNoYQGkqBdBc1LmdZmyA4C05ZBK9hZfvmg88H4Qj8X9E2EW2aCqNzEkEjgNJu3141ZkV1VS16rKpHH5m392zc2Yptxhp+2qTnTIgLrrbhBR143LwyBpBWhunn0vF4fDc4SHaPn22tSBGXjwqV1gLLaOo1MOlg5nRaVSxrJb2MjOzP6JX4w9Ye+sDLSjXe/LGaVaT3eWVHVPo6jcMiAn3Zr8uyya00ixdUqV7h4Kye07X8Z5eZlFzQ20zkXzdDhY5PB+jtiW/6wwctCBzkP4ooP2iMzZ9PQ96y0cNWA5AxwEPjNuqrf6H2yXXgJfdtT3WCRsZC90hCk2QXOIpoee3al482EtCtWg4GOklclJ4QyBONj2Nr6hs7JSHiE9dAnfQ9lHKM3zxbXtGZX0ag/KuytYGmEb+m/RSAyefqqvODOYvfnE+gnEogryp8b1GaKYUBsKWqtgrp8JAE3b/8y+kHgzk1RtotL+LSd/tvTWszxo6p9TzeWxqfFy8861hZK7ZHiGHY8gO6IUKB4/emx8HtJB0NU2pIm8/w3v57ilLmvyFkSFMsV7ENcO81aN+M5I/m7NJtgWUx5RTn3ghL1ypgy+S1jAmtTLvMJYeag2WZCaWOKKh6NaXwkNw8UEvkHAr8e5u7UYKESG17FgqifAwbKTPof0ukM9I0ikFAnJE7rc8bAiBfFBuZo76hZYKfRxY6uIoTAutqgZDEj3AAiR55dNKI4fXJuZ1HxVqP6DyNZ9RMBWzCeTDFYEkbtPDuTNfoqrtLf6iz8sqckcWJrg94rLW0pCBaCNT/AH19tZC2+0Kq50BOptfBhmkP4yAfnEWCQapK0ftbF3wCbUJ7bq07ao+weslj44vMLzVZAB4Yhx4vfY0k+T7/U/ueGi4/Lz0A6t3KmGRCtydczef3jcJtw3FvAgDCdK37PKimbTyaocCbXQtzy+pNoVCWHsx467PHN4IJcd82Ts7ieJndupewGwHAD9ipU79ev5/l4TfStguXwld8ulLVsSyZoB1D1kpej0N2YZYnKre8IjkoeBeKsFvJl9sqLgYzI3YCqJx8DsYo1FanWKeE5gFmyWk9gs1/46pIMmcKNzgA+8n5O38d267Hg+5YOZ60i66ooHdKLtQT8GhRBP64U1BQodb9SjjUWxQWuAgq+ZveKrlEX3jCYVCQ5I8UbsQb1jxLLfL1qw3MwQJ4IRXmAgymUUk3gYGfJTGuszt8ocXC1pXVq76JC2pMXJQtGkZI6XLRoNAydPWvqEdR1lrGzl+F8T8NIfC9rgMKy2VT5bsK7PfYMkyD+Q44x0dNjFARrrbiscupm9mSM0GMggXQJUNhhGp+sVXCjU1ulBWoo8wBCZPxp64tnTJClkuZkayeLazDSBEUhX3sc+0o2cOSRwRespzP+w170J38Ig2Wav/FyjR8baeBHG0kyztUkSro7Unw+VkrG+WdRkpR6jWVoUIhV0vHMovGSnfjZGwqBpIcHkKchEF+CRB+6dlGRwvSV5d5vL89JRbmnSbkT9ulInpkxtixvh1GgGo60f7q8j6FwySHQRObmUM7UnLGIsbJfhEPbqbq69VFbUYeFB8ZXqKsQuI4cF+uoK8YtG/ybVLHJl5+4/O4GBSFXnP9eIGdKAmlGgy4HcNzKP9y+rmjEJnGQfx9q/1UWIwCarE3buC01gi8YmhvvrHI19KahlPgUp7C+2tl4UjnZrC5HLc0MXr3UQ59/cZQMB69vKxiI+R9UCj2lxMFKSiyFvQta3R1Zfs2yQxVq4SZrnI2qMmO+Y+MQYu8UpbltyBgZvhWX2PXZd9nhxUcgGEflxq85cN94xgbQ3dqN74TKGDEbre0Y/6H3Ou5RTcp8k5saKMHcoRp2KGjqYlQVtnOelIs1jAzTD9P7UNVSa5FnTJ4jHVrONTmkQipswPevdoX9fEujGKC/Gu3uuK0/t364DQbMAMi8ZSa+z1HhJrTuQ8PH4SbpNwYkUTFe8emYjEjdogu6nGH6RzFFIgW/aE4U6uKgNhM4Osm1LhHPyOVeNAATDHUN4U1vivLBge6TfxYO3ryvkMYOol8RhSy+W6gxC7kY8NbE1SAaLULj3Y02Ld6KVpwQCelOyMj+ElkxVFdbT19OfVHx2N86nYRVyWn1laVujfW43wJY3LKbY0SgaZ8X3XlDhQCK3j9R1xsMFED9jG4gFN7MYsAlDLzdXAcsGy2fmxvK0xixLAgGj+KCeiJ44ATog6LGiV9nzn/BzyIzUgu0Cf+tURl32VGUkCapzi6yPEvWI6b1QoW1m+w2GiECXtsXTrq7klEG9egOCTRhDwcDQXCoYm7s5fCenTA1jIPDs87VioEMkSwlHwf4Kev5WmmynxxUBWRnpd/ncc3g+w7Isom1zgZJ05naTknW1mD8z3tZTtrwrOt7J56k3TdMzMAf73YDDiIubYwrWWB8k4beafblbghHZQWrsY6vRE7ngNq+buoicqyslaEk33cMYyUvBAdOwwWr8GtPgA/nnI15TFHPnUESlTp5SgOZcZQPL3vuh9s0XknJC008EYYxqzTcbk3qCgJT/ZchlM6Chlo3Q+QtyyCq9XcQGHYzsYHFzxlH1Vm7zm6OIi2R+q2y1Pn6hbbG7nAY8Ti1pEBFbJYCX9Q/ANHcpoOnnXb4f8jieOOtGPREXyGi9EIT/A5ft4EHNCBaMMSVKwqVJaFTypDBYtxWYfoHh/Z8MTwI+cl8xE0IXC/wHbgc6UgZXJg0cRXe/FRZCgPqAhgw2lA98HpzodhJr07vLRpLML93+fgDESrB2XRDgk/QtKeMp432z4IWmIlKCwtE6v4Tybr8bR3O3nQ3O6g7Y8InFxT9HwR0eDC0qqIe9z8G9VdVb6tZU1uVcGAy8bXcXZGjsbWWtU+QTZXKqTyKi454A61FSvNo6yFl5sckXt8y0r/fyK98SYv25/hkJImiw7Twn0ERqeQBZZ4we64hNLx52qoZgyaTR7WNbvHdeAvLyxuCuBARFqMF3oGc9SGGD7xjgYv5PEZiL55O4M4Ylb43Wb3ccu4IiXzJXDbrkvB4xe9q4jDwqjR5OYm9m8WKgp1mhNtS5bLddM16ba/wSkxtoYhaipN5TfpsXef+kMZOnpswF4BVExwI2sQHOpm/ndIn7vGO3gyzoQc/76iDp6x6x0R8qvixL2B71eNos4BFLfsPL7vmOIckdiV+xAAaTOzwLT1qoZiF5IzyiEFCJR5g2Apoda55sXGWKUqJBa5/yOHa8XLEHMcThbjljnM26s64DOYH305KyArLGgc3h0k/xLhQZqbidKFsKfcNX7VECtgELI4C4DT1zbc1/ZQzm7z/CnhlqxVoPm8gh0Aye6gdCtCaEy5benaSctr28K71YouMnGNcM/MikEwgSUk12OJeICLCxx+kx7CPPpEZ5ivote5AV9CgUteQKY3uUuVQc9SrVz0C+Hmi77FyfLamu+Q5r3RIoE2CthOKdlIcCcRu6sQ7K/y5FpT7IwI0VpOGF+oHURtQLF8lLna10RJsFWY+6G43T1GlKXGH1oQLh+tRkVD3bzyQrWNMV9OhO5XaFbU+3inRgDVy9F9hMkZuxqmsg9vn72dM0qP18Q5VV7Go8l3jxMlcXFrjt6hm5jyqXlCs1AsmaJQhnievJiZ7L+dkB/LeFWuh0nM1RyV2mnvyr805KfoKk5rEOZtrNJxNHd0nYjtGYXESzBqCT7w09iBumK87pjwiI1Fixjvp9sOHjV9vk/oJZYrlZSRhPz1KXFwxI/LFv98QaHfeA8Yj4SIT6whbiGsUSEGSzhFq1EKKCNKBSixxzoBZ0OYn1DHW2bKT+EJ/R6bRYTFxNl4kXWi3jD+BX0LPlxp/ZTc8eBAwSaSbUJ4Ma8oWKcGI9Ck+WXeCRMhdzBsOM2xVeLmh3Dp0xTW2d6lW4ILg2hpu4K3tKv1NXdSel9B7g4yEgISmaVfEwW8NRpX72eVRD0IJSoKx/Nu3rKW0rPDG9xV01KlFOGzlWVERCq4MVLSpcF7oB3iHd8nWSESXRrr1TGWX9POMLmMeawAiUteNeiqx3SK1OgCnvITnCwCmRn4Se2pyuQ957Qu1FCv3GUHBO+YMykg+jDDlKsCH+Fst4t31GGY1OQoL5QbR6eod+GeegJJ6GkQ8+acKrvxU+0AgaPAU8a2IMEQo8PUhan+y6jz7ZyTRltWqaxcATQdvOpcoQFx7MvtehYkEcHwvA2LSIdhBJC3GKLpXzX/X0/nZ/OG0dGtvyc8W/eKrsLYWvGvVp69O98M6jlP9mkB27Wk1aVXukRHSjxJZeU98cr/bSVbk6AymSQzQxUcm4haE5q1qSzM7l2ZaVMW6/H4Yl2w3cXB+Ya8zxG+JmjeONvQ/uPYzfJ9f1BPRjtI4msObc7JRkJwAmapZlif1vI7ndwbqYhNe/wsjHbIGr6EMJoNjuX0dlZQDOl9nEk0YpUu1/Jhgh48OwbVf5Vu61gBBQLRzQF4LDXQck/eaGH6WkfMO1wh1xWtEAcCnCHPxhgbiSTXEzbCR7xLCPDDUpkEU4nsPG+b/5QT5kWZYcl0M3wi+/uwUYqOtk+Y/8pTaolM8mQLhj/tcHj4nRVZYwztuPGEuICBWjKllLbRNVUo2jatoJm/9qxea1kpVlgqsnRR96kwzOblr1ng9Tb3/Jk50LfyeTPMspR15+uiB3SEFZSy7ChaVJVdADua3JhAkByXdtDq//wTVRsrLFjwoS1Bin6qXnWPdnrsY8KwPWtQ+f6soHkQmhjzipyzPtJUjT4hhJopcjH/4KE+0gYXBBnz/4GzRYTJ35AnKCc1CaEF8abe5po4wIjP6+yVn9eDx+bqHL1TJFsqgJp5KJ9krZNPYnWeIynDJJwl4MhmD2wfkI6XVkJi1nCyBvgwlmTwuq4IUlwxWfa1E0TMfwjZjq1XDVQsjn7jL68gqDT9Z2fH2OyEvXLrwSJLL2oCsa0a+NxELuQUib2Pmop1nz+EGBL86bX5MRJBSz9LOYWWP6SKMKUCVvkMnSCBrUlX0GPcDmzim0ijdj9qvFCPTKmmwewdn7tFka7k8nmj8MC/aH0NtLkBIoCifoJsPmv9adzM0p5U8F3NNYVRVgA1Jbf9DIyIjsd6IhorYbw3yeFVSuWn12cfKfd8r78sFcasYk+Gi4BjT0KYmHn8T17et75rz0WTKTOAlIE393ek2THbF+HW0rODIDQ/5/YMyMrV/BNdTMsiqRt4RKTVsdr1tM4pw4cEjmPyHYKjsAgRb8xyveDLpI3Qkn5SZhDbre9B6WketiAFuu/LvuZLINMmiD9GaDaGAs9UaO7QJsmuRknwgPfqHRY50aDvL2BLnyGUB0Sdo/BfNgQRFs6n1WMRNGUcf+8TEPVPOuaoTzUaqBa8Nsl0I9+ja51P09Svtu1tebBTCb+sN/VZc/ZpWl5IktFby5FY4P4GkShRCXJKGFgl8i13SN7vXEtaxHEXoWDADQkhepN7iNU6ZFlXLZRz/KlwZrOv+iHzDYx/BSQxA9wplAslWrOKfD8RhCv6lWaCn2yp6+nCpJkabuM9iYyD1Aa1xh15+S6J04vro1csTcsRtcTmdf4b6JB7yTeKEy+8jMG+WM5BjxlYsmV2H0JUBhQSP8B+KHDtqGzJ4xnI0WlmTv+ALQpNV+vpKm3sS/EuVr8/8if+4Wd+pCavnk/0S1J+eZjxGMmu3dpk6TpONXq2MpbVctxuL3M4qKlpqD2C1Fqqsqd8mUdqk4ncYTq4fjBCdipPlwHcprl/8+THWJOo4uGVu8BhxcAM8O84DVlrp0UumhwpkbO/8RV659DAN5QdJS2nS1RpFmnEVGhRlqFd3knQeUr8g97z+xPVyH4rlTdwxvDddxHWf/IqusFEJLGdRbHkDv+lSS0QYRlYxRGwrFAvdDrMpAlP3xfaeNbAt7auAjr1er69qr3thr0+im40h2/SNNqBHQDVsB4R2zknY2cQf97Cr7cvvtEUBXRY8N0WUcGslqu+tgGLvcyuY3sL8A/VBIo5Fxu9+hd21mbwUIMaQfRps3B4HWpyN1ShvNQLTeozn7NPZP7uQ9IrfKYR/Y8dQ29cacTjVg5HvjGwMHp1x6joM5bRxqsqkspa0V9L7ucGnsMNB0NdBEY/X1Aje4Z3/klYL2VFEMPJ/xk/k7BuwlW4UW0sexk09BULsaZhq1RrvCwVIpjuR/M3Prfq5Xu8h7EPZu3PeQfpcQVyHNEIikvAJv+/LBMopElwUw78q4FSmJHHrmAB+7N3XoYfs9fx/MiY+iguPMdEEZHYorcKs1hqZqBs01MZ6q8T+vhatVx3jTX3a/NxLt6SjwhgE2LTDGHky1r0ioy2NDA1KQm+WdEytXPqcn87trtLHeSQ+6/bg4lwoa3Lkw/r8u1cDJZCmIiplFEh1SGiEHaAB17RSzZyHhfN3cdOnEdOzZK1e0DoOOe0ewa0pWL+fcFno8EoE8h230s/iYbmwEx43yLwfw6KOUlk0CcDaQAOJSWOZKxFHaXqIedk3NiPxuDVrBH/2pMN0ZTl2ADpCDE6qkVlP1BCJNA6AoUGsX+kAQDXJGcbM3pMHqPbxpHK+yFGDN9Bo8BkgeqnhGz0Ua9hT52ePb3JQFkFTpAwVsVaHMY8Bic+lI/bcxdc5dbCuaazt1Ip/HWe8i9odWYfUroTpMhGz1+DXSqKqfPrVBH2hFTRcVeznkLaV65U963WpkNRj1jFoQmvB/1RylUfkOMv6D7/2GUf9zkJsLWZSNOv/C5M8h3GBWwdr+h2xCuwPLUQC8qxmiqIbvjskEp0aiBtLExhi3LV93x3/gB/1fEOvfYDgN4kVUgwB1tZbiAukTBoykOp3pWI02JXVUodHBSVzE/QGpdqOm6mSyw/vyz4BXUX8mrHHK7/ntAz3Ebqo5dAR/NVq59RGd0GaoaP8pS1a94WcmqphVWkk0h5AXN3fUQgM+m5f8HslNCVFcwT/uFSEoN0wRkXL8rwg+BUONOHACgHl2bU2lNotuTr4cEuvr9FjGBHMDT4srSv8ZBpaXaohib1hq2IIacdR53uLlj7s4SQtdDKhru+v8MHjldaGlQJoCujiteNT1kWTDLx7au5X1WOVgPpAk9A25fhu4dt1ADQM3NRF6i/4WUacJdb+/1wePOGh/GcmB0JN3XdsEV3+5RSMsKLfgqCBB5sRv+JNHbqST4eEvhdct74OIz0df+sSwHfZES6EEfBizXJz+ajNUcuzO2Z7kCu8PMvYFuQgvzx5B3oYeglKkOriV4qXnt8bHBN4xDAaKY/knkDIZoC39P4MxRD/dCsrbN0tAGphUuv/7O2YWOoabuzm5gxZ0NKNZm+ul8MHyvx5MeNamIIJh3qyyLF9JAI/0tm1brNMBvnSm8kLsCraS6uyVSxyjfJ4mLvaTW2Uis38SHGsQQ9OQQgjErhmGy41WEPOPd+O5CmvwvkSsOtyYg5/JWtSYUF2dwAxX7l4QvBDm/zGtVXZ8hutr0n3OCKHpPyy/NuxUwyLBMwpnmA2sNGpbuF+vLReH7K16c7M2fXpBzQrkq7HZVR0WvthCffuw8Mv7DkQ95aJaumcGLJa0nA5fCWxd/YJHxGAt8SWik1PVgLwyClnspuKAvGZ/QSM2Gjl7V3bTQmH83PajhZCONecX6/lBFJSt1CZ8SEMCap39ntS/8+//3sKnpm48nzlk3XIqmks5nqLmQXXoOvYotIrhkgVFoLIGG3gIqe7JDx85+1/HSNg9i/5NP5b3nH61SX2al1hwE6mFx2/eyLNeRqIdVBWQRacimhAmkn3UjacoUldloRdbXCBrA+bDSQ/ou2aqBMp8RZ1psJSapk1oIO4rDfODm93gvBGxBv0BNowHlHBPBnjSKKXGIQoxqgcdTovMyqP4UbkdoJ1d+b0oPzX5IHmA1EulzJ2UVLp4XR09/lcMoWEswZqR9quW8WpJ0EnuxvztvhLTtn4jJjcI2VYpiq+CqCEmFtMD75OXb9q4A5IFwUXekWQsok2Exfya9erTQliQQ9bBWOajLro/R7DLEyTZEPf/DMNvH0SIZ3wmh6SUjkp60Bnp4uLlpZFaBNXLdsIX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onblur="ASPx.ELostFocus('SearchTerm')" onchange="ASPx.EValueChanged('SearchTerm')" value="Brain Edema/etiology" type="text" /></td> </tr> </table><script id="dxss_543298418" type="text/javascript">  </script> <span class="search-icon-container"> <a class="search-icon" href="javascript:openCategorySelector(1);"><img src="/Contents/Images/search.png" /></a> </span> </li> <li class="fl"> <div class="dxbButton_MetropolisBlue SearchButton dxbButtonSys dxbTSys" id="SearchArticle" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="SearchArticle_I" class="dxb-hb" value="Find an Article" type="submit" name="ctl00$SearchArticle" /><span class="dx-vam">Find an Article</span> </div> </div><script id="dxss_842240986" type="text/javascript">  </script> </li> </ul> <div class="cl"></div> <div class="search-menu"> <span>Find an Article (56193960)</span>   <a href="/Categories" target="_blank">Find a Category (125)</a>   <a href="/SearchJournal" target="_blank">Find a Journal (6140)</a>   <a href="/searchscholar" target="_blank">Find a Scholar (3503)</a>   <a href="/searchacademicassistant" target="_blank">Find an Academic Assistant (18)</a> </div> <div class="search-menu" style="text-align:center;"> <span>Find an Article PDF (4674214)</span>   <a href="/TodayArticles" target="_self">Today's Articles (4469)</a> </div> </div> </div> </div> <script src="/bundles/UserAcademicAchievement?v=QYKvd9c2mOpOgKt90go7osO6NdxcNzivChzWAq_gw3g1"></script> <script type="text/javascript"> $(function () { try { var sort = getQueryString2('sort'); if (sort == null || sort == '') { sort = $("#SortedValue").val(); } if (sort != null && sort != '') { if ($("[field='st" + sort + "']").length) { $("[field='st" + sort + "']").addClass("sort-highlight"); } if ($("#" + sort + "sortedCheck").length) { $("#" + sort + "sortedCheck").prop("checked", true); } } $("a.readmore").click(function () { $(this).parent().toggle().next().toggle(); }); 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name="ctl00$RootHolder$RCAUserType" id="RCAUserType" /> <input type="hidden" name="ctl00$RootHolder$UserId" id="UserId" /> <input type="hidden" name="ctl00$RootHolder$IsCurrentUser" id="IsCurrentUser" /> <input type="hidden" name="ctl00$RootHolder$SortedValue" id="SortedValue" /> <div class="search-result-container cl"> <div class="search-centered cl"> <div class="search-result-center-container cl"> <div class="left-part"> <div id="RootHolder_ExportContainer" class="export-container"> <div class="dxbButton_MetropolisBlue DefaultButton-Oral dxbButtonSys dxbTSys" id="RootHolder_DownloadArticle" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_DownloadArticle_I" class="dxb-hb" value="Download" type="button" name="ctl00$RootHolder$DownloadArticle" /><span class="dx-vam">Download</span> </div> </div><script id="dxss_1963926087" type="text/javascript">  </script> </div> <div class="mnavbar"> <table class="total-count-container cl"> <tr> <td> <a href="/" target="_blank" class="white-link">Total Articles</a> </td> </tr> </table> </div> <div class="mnavbox"> <label id="RootHolder_TotalCountText" class="total-count-text">4206</label> <br /> <label style="font-size: 14px;">(from Reference Citation Analysis)</label> <div id="RootHolder_SearchArticlePDFContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithPdf" type="checkbox" id="RootHolder_ArticlesWithPdf" class="ArticlesWithPdf" onclick="SearchArticleWithPDF();" /> <label for="ArticlesWithPdf">Article PDFs (88)</label> </div> <div id="RootHolder_SearchTCContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithTC" type="checkbox" id="RootHolder_ArticlesWithTC" class="ArticlesWithTC" onclick="SearchArticleWithTC();" /> <label for="ArticlesWithTC">Cited by ≥ 1 (1260)</label> </div> </div> <div class="mnavbar" id="SearchedNameTitle"> <div> Searched Name </div> </div> <div class="mnavbox" id="SearchedNameText"> <label id="RootHolder_SearchTermText" class="search-term-text">Brain Edema/etiology</label> </div> <div id="yearFacetContainer"> <div class="mnavbar"> <div> Year Published </div> </div> <div class="mnavbox"> <div id="yearFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('year');" class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refineyearcheck" target="_self">Refine</a> </div> </div> </div> <div id="jsFacetContainer"> <div class="mnavbar"> <div> Article Statistics </div> </div> <div class="mnavbox"> <div id="jsFacetItemContainer"> </div> <div class="refine-btn-container cl" name="refinejscheck"> <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinejscheck" target="_self">Refine</a> </div> </div> </div> <div class="mnavbar"> <div> Ranked By </div> </div> <div class="mnavbox"> <ul class="ul sortedby-list"> <li> <input type="radio" id="aisortedCheck" onclick="SetSorted('ai')" name="sortedbycheck" value="aisorted" /> <a href="javascript:void(0);" name="sortedby" onclick="SetSorted('ai')" id="aisorted">Impact Index Per Article</a> </li> <li> <input type="radio" id="citedf6sortedCheck" onclick="SetSorted('citedf6')" name="sortedbycheck" value="citedf6sorted" /> <a href="javascript:void(0);" name="sortedby" onclick="SetSorted('citedf6')" id="citedf6sorted"> Citation(s) in <i>RCA</i> </a> </li> </ul> </div> <div id="RootHolder_ResultsAnalysisContainer"> <div class="mnavbar"> <div> Results Analysis </div> </div> <div class="mnavbox"> <ul class="ul analysis-list"> <li> <input type="checkbox" id="YearAnalysis" onclick="InitializeResultAnalysisBtn();" name="analysis-check" value="year" />  <label for="YearAnalysis">Year Published Analysis</label> </li> <li> <input type="checkbox" id="ArticleTypeAnalysis" onclick="InitializeResultAnalysisBtn();" name="analysis-check" value="at" 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Neuroimaging predictors of malignant brain oedema after thrombectomy in ischemic stroke: a systematic review and meta-analysis. <em class='incite-journal-name' onclick='ShowInCiteJournal(2141);'>Ann Med</em> 2025;<b>57</b>:2453635. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39834283' target='_blank'>39834283</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753013' target='_blank'>PMC11753013</a> DOI: <a href='https://dx.doi.org/10.1080/07853890.2025.2453635' target='_blank'>10.1080/07853890.2025.2453635</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/07853890.2025.2453635','39834283', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(1);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(1);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(1);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1080/07853890.2025.2453635' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(2141);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rp.tandfonline.com/submission/login' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 09/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 12/06/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 01/03/2025]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 01/22/2025]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv1" value="10.1080/07853890.2025.2453635" /> <div style="display: none" id="articleAbstract1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">We systematically reviewed neuroimaging predictors for malignant brain oedema (MBE) after thrombectomy in patients with ischemic stroke. </div><div class="abstract-label">METHODS</div><div class="abstract-content">We searched MEDLINE and EMBASE in November 2023 for studies of patients with ischemic stroke. We included studies investigating neuroimaging predictors or prediction models for MBE after thrombectomy. We estimated effect size for the association between predictors and MBE by odds ratios (ORs) or standardized mean differences (SMDs), and pooled results using random-effects modelling. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">We included 19 studies (n = 6007) with 17 neuroimaging factors and 5 models. Lower Alberta Stroke Program Early CT scores (ASPECTS, n = 3052, SMD -1.84, 95% CI -2.52 - -1.16; df = 9) and longer extent of arterial occlusion at baseline were associated with higher risk of MBE. Post-thrombectomy ASPECTS was associated with MBE in general stroke patients (n = 453, SMD -2.91, -4.02 - -1.79; df = 1), but not in successfully reperfused patients (n = 110, SMD 0.24, -0.16 - 0.65). Successful reperfusion reduced risk of MBE (n = 4851, OR 0.39, 0.30-0.51; df = 13). Contrast enhancement on CT after thrombectomy was associated with higher risk of MBE (n = 998, OR 4.82, 2.53-9.20; df = 4). More reserved brain volume capacity (baseline: n = 683, OR 0.83, 0.77-0.91, p < .001; post-thrombectomy: n = 329, OR 0.53, 0.37-0.77, p < .001) and good collaterals (baseline: n = 2301, OR 0.14, 0.10-0.20, df = 3; post-thrombectomy: n = 1006, OR 0.28, 0.15-0.51; df = 2) were associated with lower risk of MBE. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">Lower ASPECTS and longer arterial occlusion at baseline, and post-thrombectomy CT contrast enhancement increased risk of MBE. Reperfusion after thrombectomy, more reserved brain volume and good collaterals at baseline and post-thrombectomy reduced its risk. </div> <a href="javascript:ShowArticleAbstract(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+oedema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain oedema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ischemic+stroke%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ischemic stroke</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22neuroimaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">neuroimaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22systematic+review%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">systematic review</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22thrombectomy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">thrombectomy</a></li></ul> <a href="javascript:ShowArticleKeywords(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thrombectomy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thrombectomy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thrombectomy%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thrombectomy/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/surgery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroimaging%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroimaging/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Risk+Factors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Risk Factors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tomography%2c+X-Ray+Computed%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tomography, X-Ray Computed</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications/diagnostic imaging</a></li></ul> <a href="javascript:ShowArticleMeSH(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(1);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow2"> <td style="min-width: 40px; text-align: center;"> 2 </td> <td> <div id="citation2" class="article-citation"> <b>Hou Y</b>, Zhang L, Ma W, Jiang Y. NGR1 reduces neuronal apoptosis through regulation of ITGA11 following subarachnoid hemorrhage. <em class='incite-journal-name' onclick='ShowInCiteJournal(17029);'>Mol Med Rep</em> 2025;<b>31</b>:67. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39791208' target='_blank'>39791208</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11736250' target='_blank'>PMC11736250</a> DOI: <a href='https://dx.doi.org/10.3892/mmr.2025.13432' target='_blank'>10.3892/mmr.2025.13432</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3892/mmr.2025.13432','39791208', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(2);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(2);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(2);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.3892/mmr.2025.13432' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17029);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 01/12/2025]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv2" value="10.3892/mmr.2025.13432" /> <div style="display: none" id="articleAbstract2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Subarachnoid hemorrhage (SAH), a prevalent cerebrovascular condition associated with a high mortality rate, frequently results in neuronal apoptosis and an unfavorable prognosis. The adjunctive use of traditional Chinese medicine (TCM) with surgical interventions exerts a therapeutic impact on SAH, potentially by facilitating apoptosis. However, the mechanism by which TCM mediates apoptosis following SAH remains unclear. In the present study, C57BL/6J mice were subjected to the modified single‑clamp puncture method to produce an in vivo model of SAH. Treatment of these mice with notoginsenoside R1 (NGR1) prevented short‑term neurological deficits, reduced the expression levels of apoptosis‑associated proteins and mitigated brain edema. In addition, an in vitro model of SAH was established by treating HT22 mouse neuronal cells with oxyhemoglobin (OxyHb). Treatment of these cells with NGR1 resulted in attenuation of the OxyHb‑induced apoptosis. Furthermore, RNA sequencing analysis was used to examine NGR1 + OxyHb and OxyHb groups. Statistically significant changes in the expression levels of apoptosis‑associated genes in OxyHb‑stimulated HT22 cells upon administration of NGR1 were observed. The present study investigated the potential mechanism by which NGR1 mitigates neuronal apoptosis, presenting a novel therapeutic approach for treating SAH through the use of a single TCM component. </div> <a href="javascript:ShowArticleAbstract(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HT22%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HT22</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22apoptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">apoptosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22integrin+subunit+%ce%b111%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">integrin subunit α11</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22notogin%e2%80%91senoside+R1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">notogin‑senoside R1</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22subarachnoid+hemorrhage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">subarachnoid hemorrhage</a></li></ul> <a href="javascript:ShowArticleKeywords(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apoptosis%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apoptosis/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subarachnoid+Hemorrhage%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subarachnoid Hemorrhage/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subarachnoid+Hemorrhage%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subarachnoid Hemorrhage/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subarachnoid+Hemorrhage%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subarachnoid Hemorrhage/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurons%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurons/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurons%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurons/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ginsenosides%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ginsenosides/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Line%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Line</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oxyhemoglobins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oxyhemoglobins/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Regulation%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Regulation/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li></ul> <a href="javascript:ShowArticleMeSH(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(2);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow3"> <td style="min-width: 40px; text-align: center;"> 3 </td> <td> <div id="citation3" class="article-citation"> <b>Ogata A</b>, Ogasawara K, Nishihara M, Takamori A, Furukawa T, Ide T, Ito H, Yoshioka F, Nakahara Y, Masuoka J, Koike H, Irie H, Abe T. Subarachnoid iodine leakage on dual-energy computed tomography after mechanical thrombectomy is associated with malignant brain edema. <em class='incite-journal-name' onclick='ShowInCiteJournal(14700);'>J Neurointerv Surg</em> 2025;<b>17</b>:248-253. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38479800' target='_blank'>38479800</a> DOI: <a href='https://dx.doi.org/10.1136/jnis-2023-021413' target='_blank'>10.1136/jnis-2023-021413</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1136%2fjnis-2023-021413%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 1</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1136%2fjnis-2023-021413')">Impact Index Per Article: 1.0</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1136/jnis-2023-021413','38479800', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(3);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(3);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(3);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1136/jnis-2023-021413' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(14700);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 12/24/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 03/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/15/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv3" value="10.1136/jnis-2023-021413" /> <div style="display: none" id="articleAbstract3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Dual-energy computed tomography (DE-CT) can differentiate between hemorrhage and iodine contrast medium leakage following mechanical thrombectomy (MT) for acute ischemic stroke (AIS). We determined whether subarachnoid hemorrhage (SAH) and subarachnoid iodine leakage (SAIL) on DE-CT following MT were associated with malignant brain edema (MBE). </div><div class="abstract-label">METHODS</div><div class="abstract-content">We analyzed the medical records of 81 consecutive anterior circulation AIS patients who underwent MT. SAH or SAIL was diagnosed via DE-CT performed immediately after MT. We compared the procedural data, infarct volumes, MBE, and modified Rankin scale 0-2 at 90 days between patients with and without SAH and between patients with and without SAIL. Furthermore, we evaluated the association between patient characteristics and MBE. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">A total of 20 (25%) patients had SAH and 51 (63%) had SAIL. No difference in diffusion-weighted imaging (DWI)-infarct volume before MT was observed between patients with and without SAH or patients with and without SAIL. However, patients with SAIL had larger DWI-infarct volumes 1 day following MT than patients without SAIL (95 mL vs 29 mL; p=0.003). MBE occurred in 12 of 81 patients (15%); more patients with SAIL had MBE than patients without SAIL (22% vs 3%; p=0.027). Severe SAIL was significantly associated with MBE (OR, 12.5; 95% CI, 1.20-131; p=0.006), whereas SAH was not associated with MBE. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">This study demonstrated that SAIL on DE-CT immediately after MT was associated with infarct volume expansion and MBE. </div> <a href="javascript:ShowArticleAbstract(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CT%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CT</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subarachnoid%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subarachnoid</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thrombectomy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thrombectomy</a></li></ul> <a href="javascript:ShowArticleKeywords(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thrombectomy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thrombectomy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/surgery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subarachnoid+Hemorrhage%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subarachnoid Hemorrhage/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subarachnoid+Hemorrhage%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subarachnoid Hemorrhage/surgery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tomography%2c+X-Ray+Computed%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tomography, X-Ray Computed/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%2c+80+and+over%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged, 80 and over</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Iodine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Iodine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retrospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retrospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Contrast+Media%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Contrast Media</a></li></ul> <a href="javascript:ShowArticleMeSH(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(3);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow4"> <td style="min-width: 40px; text-align: center;"> 4 </td> <td> <div id="citation4" class="article-citation"> <b>Sun Y</b>, Shen B, Wang T, Zhang G, Wang P, Huang H, Shi Q, Dai Y. Restorative effects and mechanisms of neural stem cell transplantation on ischemic brain injury based on the Wnt signaling pathway. <em class='incite-journal-name' onclick='ShowInCiteJournal(11730);'>Int J Neurosci</em> 2025;<b>135</b>:219-227. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38108312' target='_blank'>38108312</a> DOI: <a href='https://dx.doi.org/10.1080/00207454.2023.2294261' target='_blank'>10.1080/00207454.2023.2294261</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/00207454.2023.2294261','38108312', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(4);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(4);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(4);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1080/00207454.2023.2294261' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11730);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 11/09/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 12/06/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 12/08/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 12/19/2023]</span></span> </div> <input type="hidden" name="doiv" id="doiv4" value="10.1080/00207454.2023.2294261" /> <div style="display: none" id="articleAbstract4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">OBJECTIVE</div><div class="abstract-content">To explore the restorative effects and mechanisms of neural stem cell (NSC) transplantation on ischemic brain injury based on the Wnt signaling pathway. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Out of 102 male KM mice, 15 were randomly selected as the control group without any intervention, while the remaining 87 underwent middle cerebral artery occlusion (MCAO) using the Zea-Longa suture method. Seven mice that did not successfully model MCAO were excluded, leaving 80 mice that successfully underwent MCAO, randomized into two groups: the Ischemic Brain Injury group (n = 40) receiving 10 μL of sterile PBS solution injected into the lateral ventricle, and the Ischemic Brain Injury + NSCs Transplantation group (n = 40) receiving 10 μL of NSCs suspension injected into the lateral ventricle. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Compared to the ischemic brain injury group, mice in the Ischemic Brain Injury + NSCs Transplantation group exhibited significantly alleviated edema in the middle cerebral artery supply area, with neurons displaying more normal morphological characteristics and fewer signs of degeneration and necrosis. The mice with NSC transplantation had significantly smaller infarct volume than those in the ischemic brain injury group (p < 0.05). The mice with NSC transplantation showed significantly lower Zea-Longa scores and a lower proportion of TUNEL-positive cells compared to those in the ischemic brain injury group (p < 0.05). </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">NSC transplantation can significantly inhibit neuronal apoptosis in the ischemic region of mice with ischemic brain injury, alleviate brain tissue edema, reduce infarct volume, and improve neurological function. The mechanism may be related to Wnt signaling pathway activation. </div> <a href="javascript:ShowArticleAbstract(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+brain+injury%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic brain injury</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Wnt+signaling+pathway%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Wnt signaling pathway</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cell+apoptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cell apoptosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22neural+stem+cell+transplantation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">neural stem cell transplantation</a></li></ul> <a href="javascript:ShowArticleKeywords(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Wnt+Signaling+Pathway%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Wnt Signaling Pathway/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neural+Stem+Cells%2ftransplantation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neural Stem Cells/transplantation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neural+Stem+Cells%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neural Stem Cells/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infarction%2c+Middle+Cerebral+Artery%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infarction, Middle Cerebral Artery/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Ischemia%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Ischemia/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stem+Cell+Transplantation%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stem Cell Transplantation/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li></ul> <a href="javascript:ShowArticleMeSH(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(4);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow5"> <td style="min-width: 40px; text-align: center;"> 5 </td> <td> <div id="citation5" class="article-citation"> <b>Verma Y</b>, Pringle C, Emsley H, Sonwalkar H, Alalade AF, Roberts GA. Perianeurysmal vasogenic oedema (PAVO): A single centre 10-year retrospective review. <em class='incite-journal-name' onclick='ShowInCiteJournal(168423);'>Neuroradiol J</em> 2025;<b>38</b>:52-58. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39066813' target='_blank'>39066813</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571596' target='_blank'>PMC11571596</a> DOI: <a href='https://dx.doi.org/10.1177/19714009241269509' target='_blank'>10.1177/19714009241269509</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1177/19714009241269509','39066813', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(5);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(5);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(5);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1177/19714009241269509' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(168423);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/30/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv5" value="10.1177/19714009241269509" /> <div style="display: none" id="articleAbstract5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">INTRODUCTION</div><div class="abstract-content">Perianeurysmal Vasogenic Oedema (PAVO) is a rare but important complication of endovascular treatment of intracranial aneurysms. Many potential risk factors have been identified including age, aneurysm size, aneurysm location, immunological profile, type of coil used, diabetes, hypertension, and smoking. PAVO can cause persistent post-procedural symptoms, subsequently increasing post-embolization morbidity. </div><div class="abstract-label">METHODS</div><div class="abstract-content">A 10-year retrospective review was conducted between 2011 and 2021 at Royal Preston Hospital, Preston, UK. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">We identified 8 patients that fit our inclusion criteria. This included 6 (75%) females and 2 (25%) males. The mean age was 64. All patients had anterior circulation aneurysms with the middle cerebral artery (MCA) being the most common site. The mean aneurysm size was 12 mm. Our patients were managed with a range of endovascular techniques. One patient had pre-treatment PAVO while 7 patients had post-embolization PAVO. Five patients were symptomatic, and 3 cases were asymptomatic with only radiological evidence of PAVO. Five patients were managed with varying courses of dexamethasone. PAVO resolution was achieved in 4 cases. The oedema significantly improved in 3 cases, but transiently progressed in 1 case. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">PAVO is a rare but important complication of endovascular management of intracranial aneurysms. We have shown that patients can be effectively managed with steroids with resultant oedema regression and symptomatic improvement. Many risk factors have been associated with PAVO, but further research is needed to better understand their role in PAVO development and help develop other therapeutic options. </div> <a href="javascript:ShowArticleAbstract(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aneurysm%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aneurysm</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22dexamethasone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">dexamethasone</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22embolisation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">embolisation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22endovascular+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">endovascular therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22oedema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">oedema</a></li></ul> <a href="javascript:ShowArticleKeywords(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retrospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retrospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intracranial+Aneurysm%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intracranial Aneurysm/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intracranial+Aneurysm%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intracranial Aneurysm/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intracranial+Aneurysm%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intracranial Aneurysm/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Embolization%2c+Therapeutic%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Embolization, Therapeutic/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endovascular+Procedures%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endovascular Procedures</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Risk+Factors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Risk Factors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dexamethasone%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dexamethasone/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li></ul> <a href="javascript:ShowArticleMeSH(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(5);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow6"> <td style="min-width: 40px; text-align: center;"> 6 </td> <td> <div id="citation6" class="article-citation"> <b>Izzo A</b>, Bove F, D'Alessandris QG, Genovese D, Tufo T, D'Ercole M, Pennisi G, Figà F, Obersnel M, Perotti V, Fuggetta MF, Bentivoglio AR, Calabresi P, Olivi A, Piano C, Montano N. Risk factors and significance of post-operative edema in Parkinson Disease patients submitted to deep brain stimulation. A ten-year case series. <em class='incite-journal-name' onclick='ShowInCiteJournal(17714);'>Neurol Sci</em> 2025;<b>46</b>:761-768. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39294408' target='_blank'>39294408</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11772388' target='_blank'>PMC11772388</a> DOI: <a href='https://dx.doi.org/10.1007/s10072-024-07774-4' target='_blank'>10.1007/s10072-024-07774-4</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s10072-024-07774-4','39294408', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(6);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(6);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(6);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(6);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1007/s10072-024-07774-4' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17714);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/20/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv6" value="10.1007/s10072-024-07774-4" /> <div style="display: none" id="articleAbstract6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Peri-electrode edema after deep brain stimulation (DBS) surgery for Parkinson Disease (PD) has been reported in up to 100% of cases. The clinical significance of this finding is unclear, with most papers suggesting a benign course. The risk factors are also poorly defined. We aimed at defining the incidence rate, the clinical significance and the predictive factors of peri-electrode edema in patients undergoing DBS for PD. </div><div class="abstract-label">METHODS</div><div class="abstract-content">We reviewed data of 119 patients treated with frameless stereotactic DBS for PD between 2012 and 2022 at our Institution. A mixed-technique targeting was adopted. Awake surgery was used in 64.7% cases; in most cases, microelectrode recording (MER) was adopted. The target was the subthalamic nucleus (STN) in 91.2% cases. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Ninety patients were included. Postoperative edema related to lead placement was noticed in 40% patients after a median time of 2 days since surgery; in 88.9% of these cases, it was limited to subcortical white matter. Symptomatic edema was registered only in one case (1.1%), confirming previous reports on the benign clinical course. The only independent predictive factor for edema onset was asleep surgery (p = 0.0451). Notably, the use of directional electrodes was not associated with an increased risk of edema at multivariable analysis. Clinical parameters including age, and timing of CT scanning, did not affect edema onset. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">We confirmed the very low rate of symptomatic edema in DBS for PD. When feasible, awake DBS using MER is the ideal technique to reduce the risk of radiologic postoperative edema. </div> <a href="javascript:ShowArticleAbstract(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Asleep%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Asleep</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Deep+brain+stimulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Deep brain stimulation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Directional+electrode%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Directional electrode</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Microelectrode+recording%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Microelectrode recording</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Parkinson+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Parkinson disease</a></li></ul> <a href="javascript:ShowArticleKeywords(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Deep+Brain+Stimulation%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Deep Brain Stimulation/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Deep+Brain+Stimulation%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Deep Brain Stimulation/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Parkinson+Disease%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Parkinson Disease/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Parkinson+Disease%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Parkinson Disease/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Risk+Factors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Risk Factors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Subthalamic+Nucleus%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Subthalamic Nucleus/surgery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retrospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retrospective Studies</a></li></ul> <a href="javascript:ShowArticleMeSH(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Universit%c3%a0+Cattolica+del+Sacro+Cuore%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Università Cattolica del Sacro Cuore</a></li></ul> <a href="javascript:ShowArticleGrant(6);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow7"> <td style="min-width: 40px; text-align: center;"> 7 </td> <td> <div id="citation7" class="article-citation"> <b>Greige T</b>, Tao BS, Dangayach NS, Gilmore EJ, O'Hana Nobleza C, Hinson HE, Chou SH, Jha RM, Wahlster S, Gebrewold MA, Lele AV, Ong CJ. Cerebral Edema Monitoring and Management Strategies: Results from an International Practice Survey. <em class='incite-journal-name' onclick='ShowInCiteJournal(17802);'>Neurocrit Care</em> 2025;<b>42</b>:207-221. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39085504' target='_blank'>39085504</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782636' target='_blank'>PMC11782636</a> DOI: <a href='https://dx.doi.org/10.1007/s12028-024-02077-0' target='_blank'>10.1007/s12028-024-02077-0</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s12028-024-02077-0','39085504', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(7);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(7);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(7);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(7);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1007/s12028-024-02077-0' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17802);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/02/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv7" value="10.1007/s12028-024-02077-0" /> <div style="display: none" id="articleAbstract7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Cerebral edema is a common, potentially life-threatening complication in critically ill patients with acute brain injury. However, uncertainty remains regarding best monitoring and treatment strategies, which may result in wide practice variations. </div><div class="abstract-label">METHODS</div><div class="abstract-content">A 20-question digital survey on monitoring and management practices was disseminated between July 2022 and May 2023 to clinicians who manage cerebral edema. The survey was promoted through email, social media, medical conferences, and the Neurocritical Care Society Web site. We used the χ2 test, Fisher's exact test, analysis of variance, and logistic regression to report factors associated with practice variation, diagnostic monitoring methods, and therapeutic triggers based on practitioner and institutional characteristics. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Of 321 participants from 160 institutions in 30 countries, 65% were from university-affiliated centers, 74% were attending physicians, 38% were woman, 38% had neurology training, and 55% were US-based. Eighty-four percent observed practice variations at their institutions, with "provider preference" being cited most (87%). Factors linked to variation included gender, experience, university affiliation, and practicing outside the United States. University affiliates tended to use more tests (median 3.87 vs. 3.43, p = 0.01) to monitor cerebral edema. Regarding management practices, 20% of respondents' preferred timing for decompressive hemicraniectomy was after 48 h, and 37% stated that radiographic findings only would be sufficient to trigger surgery. Fifty percent of respondents reported initiating osmotic therapy based on radiographic indications or prophylactically. There were no significant associations between management strategies and respondent or center characteristics. Twenty-seven percent of respondents indicated that they acquired neuroimaging at intervals of 24 h or less. Within this group, attending physicians were more likely to follow this practice (65.5% vs. 34.5%, p = 0.04). </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">Cerebral edema monitoring and management strategies vary. Features associated with practice variations include both practitioner and institutional characteristics. We provide a foundation for understanding practice patterns that is crucial for informing educational initiatives, standardizing guidelines, and conducting future trials. </div> <a href="javascript:ShowArticleAbstract(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cerebral+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cerebral edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Decompressive+craniectomy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Decompressive craniectomy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osmotic+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osmotic therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Practice+variation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Practice variation</a></li></ul> <a href="javascript:ShowArticleKeywords(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Practice+Patterns%2c+Physicians%27%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Practice Patterns, Physicians'/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Surveys+and+Questionnaires%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Surveys and Questionnaires</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Health+Care+Surveys%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Health Care Surveys</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Critical+Care%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Critical Care/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Decompressive+Craniectomy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Decompressive Craniectomy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Monitoring%2c+Physiologic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Monitoring, Physiologic</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Internationality%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Internationality</a></li></ul> <a href="javascript:ShowArticleMeSH(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">U01 NS124613 NINDS NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R21 NS131689 NINDS NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">K23 NS110828 NINDS NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">K23 NS116033 NINDS NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 NS115815 NINDS NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(7);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow8"> <td style="min-width: 40px; text-align: center;"> 8 </td> <td> <div id="citation8" class="article-citation"> <b>Ong CJ</b>, Huang Q, Kim ISY, Pohlmann J, Chatzidakis S, Brush B, Zhang Y, Du Y, Malinger LA, Benjamin EJ, Dupuis J, Greer DM, Smirnakis SM, Trinquart L. Association of Dynamic Trajectories of Time-Series Data and Life-Threatening Mass Effect in Large Middle Cerebral Artery Stroke. <em class='incite-journal-name' onclick='ShowInCiteJournal(17802);'>Neurocrit Care</em> 2025;<b>42</b>:77-89. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38955931' target='_blank'>38955931</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693775' target='_blank'>PMC11693775</a> DOI: <a href='https://dx.doi.org/10.1007/s12028-024-02036-9' target='_blank'>10.1007/s12028-024-02036-9</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s12028-024-02036-9','38955931', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(8);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(8);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(8);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(8);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1007/s12028-024-02036-9' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17802);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 11/14/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv8" value="10.1007/s12028-024-02036-9" /> <div style="display: none" id="articleAbstract8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Life-threatening, space-occupying mass effect due to cerebral edema and/or hemorrhagic transformation is an early complication of patients with middle cerebral artery stroke. Little is known about longitudinal trajectories of laboratory and vital signs leading up to radiographic and clinical deterioration related to this mass effect. </div><div class="abstract-label">METHODS</div><div class="abstract-content">We curated a retrospective data set of 635 patients with large middle cerebral artery stroke totaling 95,463 data points for 10 longitudinal covariates and 40 time-independent covariates. We assessed trajectories of the 10 longitudinal variables during the 72 h preceding three outcomes representative of life-threatening mass effect: midline shift ≥ 5 mm, pineal gland shift (PGS) > 4 mm, and decompressive hemicraniectomy (DHC). We used a "backward-looking" trajectory approach. Patients were aligned based on outcome occurrence time and the trajectory of each variable was assessed before that outcome by accounting for cases and noncases, adjusting for confounders. We evaluated longitudinal trajectories with Cox proportional time-dependent regression. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Of 635 patients, 49.0% were female, and the mean age was 69 years. Thirty five percent of patients had midline shift ≥ 5 mm, 24.3% of patients had PGS > 4 mm, and 10.7% of patients underwent DHC. Backward-looking trajectories showed mild increases in white blood cell count (10-11 K/UL within 72 h), temperature (up to half a degree within 24 h), and sodium levels (1-3 mEq/L within 24 h) before the three outcomes of interest. We also observed a decrease in heart rate (75-65 beats per minute) 24 h before DHC. We found a significant association between increased white blood cell count with PGS > 4 mm (hazard ratio 1.05, p value 0.007). </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">Longitudinal profiling adjusted for confounders demonstrated that white blood cell count, temperature, and sodium levels appear to increase before radiographic and clinical indicators of space-occupying mass effect. These findings will inform the development of multivariable dynamic risk models to aid prediction of life-threatening, space-occupying mass effect. </div> <a href="javascript:ShowArticleAbstract(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cerebral+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cerebral edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+stroke%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic stroke</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Midline+shift%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Midline shift</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Trajectory+analysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Trajectory analysis</a></li></ul> <a href="javascript:ShowArticleKeywords(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infarction%2c+Middle+Cerebral+Artery%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infarction, Middle Cerebral Artery/surgery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infarction%2c+Middle+Cerebral+Artery%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infarction, Middle Cerebral Artery/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infarction%2c+Middle+Cerebral+Artery%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infarction, Middle Cerebral Artery/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retrospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retrospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Decompressive+Craniectomy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Decompressive Craniectomy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pineal+Gland%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pineal Gland/surgery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pineal+Gland%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pineal Gland/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%2c+80+and+over%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged, 80 and over</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Longitudinal+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Longitudinal Studies</a></li></ul> <a href="javascript:ShowArticleMeSH(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">K23 NS116033 NINDS NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22American+Heart+Association-American+Stroke+Association%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">18SFRN34110082 American Heart Association-American Stroke Association</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 NS102574 NINDS NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">K23NS116033 NINDS NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RO1 EY024019 NINDS NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22American+Heart+Association-American+Stroke+Association%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">18SFRN34150007 American Heart Association-American Stroke Association</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22American+Heart+Association%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">AHA 18SFRN34150007 American Heart Association</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NHLBI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 HL092577 NHLBI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22American+Heart+Association-American+Stroke+Association%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">AHA_18SFRN34110082 American Heart Association-American Stroke Association</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NEI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 EY024019 NEI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22American+Heart+Association%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">23CDA1041762 American Heart Association</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NHLBI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01HL092577 NHLBI NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(8);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow9"> <td style="min-width: 40px; text-align: center;"> 9 </td> <td> <div id="citation9" class="article-citation"> <b>Qian A</b>, Zheng L, Duan J, Li L, Xing W, Tang S. Hyponatremia is associated with malignant brain edema after mechanical thrombectomy in acute ischemic stroke. <em class='incite-journal-name' onclick='ShowInCiteJournal(4084);'>BMC Neurol</em> 2025;<b>25</b>:41. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39875844' target='_blank'>39875844</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773710' target='_blank'>PMC11773710</a> DOI: <a href='https://dx.doi.org/10.1186/s12883-025-04051-5' target='_blank'>10.1186/s12883-025-04051-5</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1186/s12883-025-04051-5','39875844', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(9);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(9);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(9);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(9);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1186/s12883-025-04051-5' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(4084);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 11/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 01/21/2025]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 01/30/2025]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv9" value="10.1186/s12883-025-04051-5" /> <div style="display: none" id="articleAbstract9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Hyponatremia (< 135 mmol/L) is the most common electrolyte disturbance in patients with stroke. However, few studies have reported the relationship between hyponatremia at admission and outcomes in patients with acute ischemic stroke (AIS) treated with mechanical thrombectomy (MT). This study is aimed to explore the association between hyponatremia and clinical outcomes following MT. </div><div class="abstract-label">METHODS</div><div class="abstract-content">A retrospective study was conducted at our center. The primary outcome was postoperative malignant brain edema (MBE). The secondary outcomes included mortality and adverse function at the 90-day follow-up, which were defined as modified Rankin scale scores of 6 and > 2, respectively. Patients were classified into hyponatremia and nonhyponatremia groups based on their serum sodium concentration at admission before drug use. The occurrence of MBE was evaluated via computed tomography after MT, and 90-day outcomes were obtained through in-person interviews at the clinic or via telephone. Multivariate analysis was performed to investigate the associations among postoperative MBE, 90-day mortality, adverse function and hyponatremia. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">A total of 342 patients were enrolled into the study, of whom 52 (15.2%) had hyponatremia, 86 (25.1%) developed postoperative MBE, 93 (27.2%) died within 90 days after MT, and 201 (58.8%) had adverse functions at the 90-day follow-up. Multivariate analysis revealed that hyponatremia was significantly associated with postoperative MBE (odds ratio [OR] 3.91, 95% confidence interval [CI] 1.66 - 9.23, p = 0.002), 90-day mortality (OR 5.49, 95% CI 2.48 - 12.14, p < 0.001), and 90-day adverse function (OR 3.25, 95% CI 1.29 - 8.12, p = 0.012). In addition, mediation analysis revealed that postoperative MBE may partially account for the 90-day mortality/adverse function of patients with hyponatremia (regression coefficients changed by 18.6% and 23.9%, respectively). </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">Hyponatremia is an independent predictor of postoperative MBE, 90-day mortality, and adverse function. Correction of hyponatremia may reduce the postoperative MBE to improve the prognosis of patients. </div> <a href="javascript:ShowArticleAbstract(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+ischemic+stroke%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute ischemic stroke</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adverse+function%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adverse function</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hyponatremia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hyponatremia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Malignant+brain+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Malignant brain edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mechanical+thrombectomy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mechanical thrombectomy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mortality%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mortality</a></li></ul> <a href="javascript:ShowArticleKeywords(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hyponatremia%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hyponatremia/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retrospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retrospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/surgery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fblood%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/blood</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thrombectomy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thrombectomy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thrombectomy%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thrombectomy/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%2c+80+and+over%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged, 80 and over</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Treatment+Outcome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Treatment Outcome</a></li></ul> <a href="javascript:ShowArticleMeSH(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Research+Project+on+Medical+Youth+Innovation+in+Sichuan+Province%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Q22014 Research Project on Medical Youth Innovation in Sichuan Province</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Medical+Research+Project+of+Sichuan+Province%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">S23006 Medical Research Project of Sichuan Province</a></li></ul> <a href="javascript:ShowArticleGrant(9);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow10"> <td style="min-width: 40px; text-align: center;"> 10 </td> <td> <div id="citation10" class="article-citation"> <b>Singh S</b>, Kumar T, Narayan S. Unilateral diffuse cytotoxic oedema and crossed cerebellar diaschisis related to status epilepticus. <em class='incite-journal-name' onclick='ShowInCiteJournal(3964);'>BMJ Case Rep</em> 2025;<b>18</b>:e260783. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39870463' target='_blank'>39870463</a> DOI: <a href='https://dx.doi.org/10.1136/bcr-2024-260783' target='_blank'>10.1136/bcr-2024-260783</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1136/bcr-2024-260783','39870463', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(10);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(10);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(10);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1136/bcr-2024-260783' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3964);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 01/29/2025]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv10" value="10.1136/bcr-2024-260783" /> <div style="display: none" id="articleAbstract10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Postseizure brain changes on imaging are well-known facts. Many times, oedematous brain changes can mimic ischaemic stroke. Crossed cerebellar diaschisis refers to a depression in metabolism, affecting the cerebellar hemisphere due to contralateral supratentorial abnormalities. We report a unique case of postictal unilateral pan hemispheric diffuse brain oedema with simultaneous crossed cerebellar diaschisis, which is a very rare phenomenon. </div> <a href="javascript:ShowArticleAbstract(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+stem+%2f+cerebellum%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain stem / cerebellum</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Epilepsy+and+seizures%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Epilepsy and seizures</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuroimaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuroimaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Radiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Radiology</a></li></ul> <a href="javascript:ShowArticleKeywords(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Status+Epilepticus%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Status Epilepticus/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cerebellum%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cerebellum/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cerebellum%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cerebellum/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cerebellar+Diseases%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cerebellar Diseases/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cerebellar+Diseases%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cerebellar Diseases/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnetic+Resonance+Imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnetic Resonance Imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diagnosis%2c+Differential%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diagnosis, Differential</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li></ul> <a href="javascript:ShowArticleMeSH(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(10);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow11"> <td style="min-width: 40px; text-align: center;"> 11 </td> <td> <div id="citation11" class="article-citation"> <b>Wang Y</b>, Chang H, Bai P, Chen J. Evaluation of contralateral arterial flow compensation using transcranial Doppler in acute internal carotid artery occlusion and implications for neurological outcome. <em class='incite-journal-name' onclick='ShowInCiteJournal(20954);'>Sci Rep</em> 2025;<b>15</b>:2998. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39849031' target='_blank'>39849031</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758004' target='_blank'>PMC11758004</a> DOI: <a href='https://dx.doi.org/10.1038/s41598-025-86640-5' target='_blank'>10.1038/s41598-025-86640-5</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1038/s41598-025-86640-5','39849031', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(11);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(11);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(11);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(11);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1038/s41598-025-86640-5' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(20954);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 01/13/2025]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 01/25/2025]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv11" value="10.1038/s41598-025-86640-5" /> <div style="display: none" id="articleAbstract11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Acute internal carotid artery occlusion (AICAO) can result in malignant cerebral edema and unfavorable patient outcomes. This study evaluated the utility of transcranial Doppler (TCD) in assessing contralateral flow compensation and predicting outcomes in patients with AICAO. We enrolled 51 patients within 6 h of symptom onset and conducted TCD examinations to evaluate collateral circulation. Among the 51 patients, 40 (78.4%) had collateral flow. TCD showed excellent agreement with magnetic resonance angiography (MRA)/CT angiography (CTA) in assessing anterior communicating artery (ACoA) status (kappa = 0.873, p < 0.001). Our findings indicated that the absence of collaterals (OR = 7.649, p = 0.032), younger age (OR = 0.907, p = 0.048), and lower Alberta Stroke Program Early CT Score 24 h after onset (ASPECTs1) (OR = 0.276, p = 0.025) were independent predictors of malignant cerebral edema. Additionally, advanced age, elevated National Institutes of Health Stroke Scale Score (NIHSSs) in the Emergency Department, sole extracranial-to-intracranial collateral circulation (EICC), and absence ACoA were independently associated with worse outcomes (all p < 0.05). In conclusion, TCD evaluation of collateral circulation in AICAO patients can effectively predict the risk of malignant cerebral edema, with ACoA presence correlating with favorable outcomes and sole EICC linked to poorer prognosis. While age, NIHSSs and ASPECTs also contribute, TCD's assessment of collaterals provides key insights for patient management. </div> <a href="javascript:ShowArticleAbstract(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+internal+carotid+artery+occlusion%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute internal carotid artery occlusion</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Collateral+circulations%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Collateral circulations</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Malignant+cerebral+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Malignant cerebral edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Modified+Rankin+Scale%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Modified Rankin Scale</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcranial+Doppler%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcranial Doppler</a></li></ul> <a href="javascript:ShowArticleKeywords(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ultrasonography%2c+Doppler%2c+Transcranial%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ultrasonography, Doppler, Transcranial/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carotid+Artery%2c+Internal%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carotid Artery, Internal/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carotid+Artery%2c+Internal%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carotid Artery, Internal/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Collateral+Circulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Collateral Circulation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cerebrovascular+Circulation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cerebrovascular Circulation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnetic+Resonance+Angiography%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnetic Resonance Angiography/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carotid+Stenosis%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carotid Stenosis/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carotid+Stenosis%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carotid Stenosis/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Computed+Tomography+Angiography%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Computed Tomography Angiography/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%2c+80+and+over%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged, 80 and over</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prognosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prognosis</a></li></ul> <a href="javascript:ShowArticleMeSH(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Research+was+supported+by+Medical+Health+Science+and+technology+Project+of+Inner+Mongolia+Health+Commission%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">202201001 Research was supported by Medical Health Science and technology Project of Inner Mongolia Health Commission</a></li></ul> <a href="javascript:ShowArticleGrant(11);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow12"> <td style="min-width: 40px; text-align: center;"> 12 </td> <td> <div id="citation12" class="article-citation"> <b>Yamashita S</b>, Fujimori D, Igari S, Yamamoto Y, Mizuuchi T, Mori H, Hayashi H, Tahara K, Sawada T. Unique presentation of acute neuro-Behçet's disease involving a cytotoxic oedema core surrounded by vasogenic oedema. <em class='incite-journal-name' onclick='ShowInCiteJournal(168086);'>Mod Rheumatol Case Rep</em> 2025;<b>9</b>:188-192. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38874595' target='_blank'>38874595</a> DOI: <a href='https://dx.doi.org/10.1093/mrcr/rxae032' target='_blank'>10.1093/mrcr/rxae032</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1093/mrcr/rxae032','38874595', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(12);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(12);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(12);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1093/mrcr/rxae032' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(168086);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/19/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 04/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 05/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 06/15/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv12" value="10.1093/mrcr/rxae032" /> <div style="display: none" id="articleAbstract12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">A 53-year-old woman with recurrent stomatitis, genital ulcers, and folliculitis was admitted to Tokyo Medical University Hospital after experiencing visual disturbances for the past 2 weeks and a nonthrobbing headache for the past 3 days. She had also developed numbness in her left extremities. An ophthalmological examination revealed inflammatory changes in the eye. Cerebrospinal fluid analysis showed increased cell counts, protein, and interleukin-6 levels. Brain magnetic resonance imaging revealed multiple high signal intensities on T2-weighted/fluid-attenuated inversion recovery images of the pons and occipital and parietal lobes. The T2-weighted/fluid-attenuated inversion recovery high-signal-intensity lesion in the pons was hyperintense on diffusion-weighted imaging and hypointense on apparent diffusion coefficient mapping, suggesting cytotoxic oedema. Another high-signal-intensity lesion on T2-weighted/fluid-attenuated inversion recovery was isointense to hyperintense on diffusion-weighted imaging and hyperintense on apparent diffusion coefficient, indicating vasogenic oedema. The vasogenic oedema in the left occipital lobe contained a small core that was hyperintense on diffusion-weighted imaging and hypointense on apparent diffusion coefficient, suggesting cytotoxic oedema. The patient was diagnosed with acute neuro-Behçet's disease and responded well to high-dose glucocorticoid and colchicine treatment. The present report emphasises that patients with acute neuro-Behçet's disease may present with cytotoxic oedema in the pons and cerebral spheres. Further reports of similar cases would contribute to a better understanding of the role of cytotoxic oedema in the pathophysiology of neuro-Behçet's disease and help elucidate the mechanisms underlying a unique presentation characterised by a central cytotoxic oedema core within vasogenic oedema. </div> <a href="javascript:ShowArticleAbstract(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Beh%c3%a7et%e2%80%99s+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Behçet’s disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22acute+neuro-Beh%c3%a7et%e2%80%99s+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">acute neuro-Behçet’s disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cytotoxic+oedema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cytotoxic oedema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22pons%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">pons</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22vasogenic+oedema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">vasogenic oedema</a></li></ul> <a href="javascript:ShowArticleKeywords(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Behcet+Syndrome%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Behcet Syndrome/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Behcet+Syndrome%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Behcet Syndrome/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Colchicine%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Colchicine/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnetic+Resonance+Imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnetic Resonance Imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glucocorticoids%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glucocorticoids/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diffusion+Magnetic+Resonance+Imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diffusion Magnetic Resonance Imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Treatment+Outcome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Treatment Outcome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/diagnostic imaging</a></li></ul> <a href="javascript:ShowArticleMeSH(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(12);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow13"> <td style="min-width: 40px; text-align: center;"> 13 </td> <td> <div id="citation13" class="article-citation"> <b>Mandell M</b>, Grassia F, Riaz M. Malignant Cerebral Edema After Cranioplasty: A Case Report and Literature Insights. <em class='incite-journal-name' onclick='ShowInCiteJournal(162930);'>AMERICAN JOURNAL OF CASE REPORTS</em> 2025;<b>26</b>:e946230. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39774935' target='_blank'>39774935</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11725662' target='_blank'>PMC11725662</a> DOI: <a href='https://dx.doi.org/10.12659/ajcr.946230' target='_blank'>10.12659/ajcr.946230</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.12659/ajcr.946230','39774935', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(13);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(13);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(13);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.12659/ajcr.946230' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(162930);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 11/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 01/11/2025]</span></span> </div> <input type="hidden" name="doiv" id="doiv13" value="10.12659/ajcr.946230" /> <div style="display: none" id="articleAbstract13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">BACKGROUND Decompressive craniectomy is a common life-saving intervention in the setting of elevated intracranial pressure. Cranioplasty restores the calvarium and intracranial physiology once swelling recedes. Cranioplasty is often thought of as a low-risk intervention. However, numerous reports indicate that malignant cerebral edema (MCE) is an often-fatal complication of an otherwise uneventful cranioplasty. A careful review of the literature is needed to better understand this devastating condition. CASE REPORT A 41-year-old man presented after suffering a gunshot wound to the right frontal lobe. Upon initial evaluation, the patient had grossly visible brain matter, left-sided hemiparesis with a Glascow Coma Score (GCS) of 11, and vital signs concerning for elevated intracranial pressure. Computed tomography (CT) showed right-sided intraparenchymal and subarachnoid hemorrhage with a 5 mm leftward midline shift. The patient was taken to the operating room (OR) for right fronto-parietal craniectomy. Over the next 3 months, he recovered steadily and underwent PEEK cranioplasty on post-operative day 83. Pre-operative CT showed sunken skin flap syndrome with an 8-mm midline shift. Following an uneventful cranioplasty, he failed to regain consciousness. Examination revealed absent brainstem reflexes. CT showed global diffuse cerebral edema. The patient was declared brain dead. CONCLUSIONS Continued research is needed to better understand the pathophysiology of malignant cerebral edema so that future incidences may be prevented. A combination of negative-pressure suction drainage, sunken skin flap syndrome, and delayed time to cranioplasty likely play a significant role in the evolution of MCE. We urge neurosurgeons to consider the likelihood of MCE and adapt surgical planning accordingly. </div> <a href="javascript:ShowArticleAbstract(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22brain+death%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">brain death</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22craniocerebral+trauma%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">craniocerebral trauma</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22neurosurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">neurosurgery</a></li></ul> <a href="javascript:ShowArticleKeywords(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Decompressive+Craniectomy%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Decompressive Craniectomy/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Wounds%2c+Gunshot%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Wounds, Gunshot/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Wounds%2c+Gunshot%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Wounds, Gunshot/surgery</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tomography%2c+X-Ray+Computed%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tomography, X-Ray Computed</a></li></ul> <a href="javascript:ShowArticleMeSH(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(13);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow14"> <td style="min-width: 40px; text-align: center;"> 14 </td> <td> <div id="citation14" class="article-citation"> <b>Deng Q</b>, Yang Y, Bai H, Li F, Zhang W, He R, Li Y. Predictive Value of Machine Learning Models for Cerebral Edema Risk in Stroke Patients: A Meta-Analysis. <em class='incite-journal-name' onclick='ShowInCiteJournal(4002);'>Brain Behav</em> 2025;<b>15</b>:e70198. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39778917' target='_blank'>39778917</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11710891' target='_blank'>PMC11710891</a> DOI: <a href='https://dx.doi.org/10.1002/brb3.70198' target='_blank'>10.1002/brb3.70198</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1002/brb3.70198','39778917', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(14);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(14);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(14);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1002/brb3.70198' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(4002);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://mc.manuscriptcentral.com/brainandbehavior' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 11/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/28/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 01/11/2025]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv14" value="10.1002/brb3.70198" /> <div style="display: none" id="articleAbstract14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">INTRODUCTION</div><div class="abstract-content">Stroke patients are at high risk of developing cerebral edema, which can have severe consequences. However, there are currently few effective tools for early identification or prediction of this risk. As machine learning (ML) is increasingly used in clinical practice, its effectiveness in predicting cerebral edema risk in stroke patients has been explored. Nonetheless, the lack of systematic evidence on its predictive value challenges the update of simple and user-friendly risk assessment tools. Therefore, we conducted a systematic review to evaluate the predictive utility of ML for cerebral edema in stroke patients. </div><div class="abstract-label">METHODS</div><div class="abstract-content">We searched PubMed, Embase, Web of Science, and the Cochrane Database up to February 21, 2024. The risk of bias in selected studies was assessed using a bias assessment tool for predictive models. Meta-analysis synthesized results from validation sets. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">We included 22 studies with 25,096 stroke patients and 25 models, which were constructed using common and interpretable clinical features. In the validation cohort, the models achieved a concordance index (c-index) of 0.840 (95% CI: 0.810-0.871) for predicting poststroke cerebral edema, with a sensitivity of 0.76 (95% CI: 0.72-0.79) and a specificity of 0.87 (95% CI: 0.83-0.90). </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">ML models are significant in predicting poststroke cerebral edema, providing clinicians with a powerful prognostic tool. However, radiomics-based research was not included. We anticipate advancements in radiomics research to enhance the predictive power of ML for poststroke cerebral edema. </div> <a href="javascript:ShowArticleAbstract(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cerebral+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cerebral edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22machine+learning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">machine learning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22predictive+modeling%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">predictive modeling</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22stroke%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">stroke</a></li></ul> <a href="javascript:ShowArticleKeywords(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Machine+Learning%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Machine Learning</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stroke%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stroke/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Risk+Assessment%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Risk Assessment/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Predictive+Value+of+Tests%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Predictive Value of Tests</a></li></ul> <a href="javascript:ShowArticleMeSH(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(14);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow15"> <td style="min-width: 40px; text-align: center;"> 15 </td> <td> <div id="citation15" class="article-citation"> <b>McGrath K</b>, Frain M, Hey G, Rahman M. Complications following laser interstitial thermal therapy: a review. <em class='incite-journal-name' onclick='ShowInCiteJournal(17686);'>Neurochirurgie</em> 2025;<b>71</b>:101604. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39413572' target='_blank'>39413572</a> DOI: <a href='https://dx.doi.org/10.1016/j.neuchi.2024.101604' target='_blank'>10.1016/j.neuchi.2024.101604</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.neuchi.2024.101604','39413572', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(15);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(15);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(15);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1016/j.neuchi.2024.101604' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17686);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/18/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv15" value="10.1016/j.neuchi.2024.101604" /> <div style="display: none" id="articleAbstract15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Laser interstitial thermal therapy (LITT) is being performed more frequently for various lesions within neurosurgery, including epileptic foci, vascular malformations, and tumors. Though this technique generally has an excellent safety profile, it is important to be aware of potential complications. Thermal ablation of tissue leads to disruption of the blood brain barrier as well as an inflammatory response both of which cause the majority of complications from LITT. The most common complications of LITT include cerebral edema, focal neurologic deficits, and intracranial hemorrhage. Few studies have identified factors predicting development of these complications, but many of these are transient and resolve without intervention. Modifications to LITT technique that allows better visualization of patient anatomy along the tract, such as fusing vascular imaging with intraoperative MRI, reduce the risk of complications. </div> <a href="javascript:ShowArticleAbstract(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Complications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22LITT%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">LITT</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Laser+interstitial+thermal+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Laser interstitial thermal therapy</a></li></ul> <a href="javascript:ShowArticleKeywords(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Laser+Therapy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Laser Therapy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Laser+Therapy%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Laser Therapy/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurosurgical+Procedures%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurosurgical Procedures/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurosurgical+Procedures%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurosurgical Procedures/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Neoplasms%2fsurgery%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Neoplasms/surgery</a></li></ul> <a href="javascript:ShowArticleMeSH(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(15);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow16"> <td style="min-width: 40px; text-align: center;"> 16 </td> <td> <div id="citation16" class="article-citation"> <b>Luo J</b>, Zhao X, Xiao M, Wei L, Zhu Z, Li B, Ji Z, Wu Y, Lin Z, Pan S, Huang K. Clearance rate of contrast extravasation after endovascular therapy is associated with functional outcome and mediated by cerebral edema. <em class='incite-journal-name' onclick='ShowInCiteJournal(169693);'>J Cereb Blood Flow Metab</em> 2025;<b>45</b>:66-76. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39161252' target='_blank'>39161252</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572124' target='_blank'>PMC11572124</a> DOI: <a href='https://dx.doi.org/10.1177/0271678x241275763' target='_blank'>10.1177/0271678x241275763</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1177/0271678x241275763','39161252', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(16);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(16);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(16);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1177/0271678x241275763' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169693);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://mc.manuscriptcentral.com/jcbfm' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/21/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv16" value="10.1177/0271678x241275763" /> <div style="display: none" id="articleAbstract16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The brain's function of clearance and transport is closely related to the prognosis of acute ischemic stroke (AIS). In this study, we proposed a novel method, clearance rate of contrast extravasation (CROCE), to measure brain clearance and transport function in AIS patients undergoing endovascular therapy (EVT), and examined its association with cerebral edema and functional outcome. We conducted a pooled analysis of AIS patients of anterior circulation large vessel occlusion who underwent EVT in two academic hospitals. Patients who experienced contrast extravasation but not intracerebral hemorrhage following EVT were included. CROCE was defined as the mass of contrast agent cleared per hour on non-contrast CT (NCCT). Among the 215 patients finally included, we found that high CROCE was significantly associated with 90-day favorable functional outcome, and the association retained after adjustment for potential confounders. Different correlation analysis demonstrated a significant correlation between CROCE, cerebral edema, and functional outcome. Further mediation analysis revealed that cerebral edema mediated the effect of CROCE on functional outcome. These results revealed that CROCE may be a promising indicator of brain clearance function for patients who received EVT and had contrast extravasation. </div> <a href="javascript:ShowArticleAbstract(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+stroke%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic stroke</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22brain+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">brain edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22clearance+rate%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">clearance rate</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22contrast+media%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">contrast media</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22endovascular+procedures%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">endovascular procedures</a></li></ul> <a href="javascript:ShowArticleKeywords(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endovascular+Procedures%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endovascular Procedures/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endovascular+Procedures%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endovascular Procedures/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Extravasation+of+Diagnostic+and+Therapeutic+Materials%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Extravasation of Diagnostic and Therapeutic Materials</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Contrast+Media%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Contrast Media/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Treatment+Outcome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Treatment Outcome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic Stroke/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tomography%2c+X-Ray+Computed%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tomography, X-Ray Computed</a></li></ul> <a href="javascript:ShowArticleMeSH(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(16);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow17"> <td style="min-width: 40px; text-align: center;"> 17 </td> <td> <div id="citation17" class="article-citation"> <b>Deng A</b>, Xu H, Gaynor BJ, Cole JW, Giese AK, Schirmer MD, McArdle PF, Mitchell BD, Wu O, Rost NS, Kittner SJ. The association of SUR1 polymorphisms with acute infarct size: The MRI-GENIE study. <em class='incite-journal-name' onclick='ShowInCiteJournal(169278);'>J Stroke Cerebrovasc Dis</em> 2025;<b>34</b>:108109. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39489406' target='_blank'>39489406</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11710974' target='_blank'>PMC11710974</a> DOI: <a href='https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2024.108109' target='_blank'>10.1016/j.jstrokecerebrovasdis.2024.108109</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jstrokecerebrovasdis.2024.108109','39489406', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(17);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(17);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(17);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(17);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1016/j.jstrokecerebrovasdis.2024.108109' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169278);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/05/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv17" value="10.1016/j.jstrokecerebrovasdis.2024.108109" /> <div style="display: none" id="articleAbstract17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">The sulfonylurea receptor 1 (SUR1) is a known mediator of cerebral edema in large ischemic strokes, however, genetically induced response variability has yet to be evaluated. SUR1, encoded by the ABCC8 gene, is an ion channel regulator in ischemia-induced cerebral edema. Previous studies in severe traumatic brain injury demonstrated four tag single nucleotide polymorphisms (SNPs) of the ABCC8 gene to be associated with cerebral edema and functional outcome. We hypothesized that these four SNPs would also be associated with acute infarct size and functional outcome in non-lacunar ischemic stroke. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Using 2,205 MRI-GENetics Interface Exploration (MRI-GENIE) study subjects with acute non-lacunar ischemic strokes, we evaluated the association between the 4 ABCC8 tag-SNPs and stroke infarct size (as measured in a standardized fashion from MRIs using diffusion-weighted imaging), adjusting for age, sex and population stratification. Modified Rankin scale (mRS) outcome was available at 3-months for a subset of 798 strokes in MRI-GENIE and was evaluated as a dichotomous variable (0-2 vs. 3-6), adjusting for age, sex, stroke severity (baseline NIH Stroke Scale (NIHSS) score), and population stratification. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">The candidate SNPs, rs7105832, rs2237982, rs11024286, rs4148622, were not statistically associated with DWI (beta = -0.065, -0.057, 0.037, 0.018; p = 0.053, 0.078, 0.28, 0.61) or dichotomous mRS outcome (OR = 0.80, 0.86, 1.14, 0.90; p = 0.117, 0.289, 0.353, 0.502). </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">rs7105832, rs2237982, rs11024286, rs4148622 polymorphisms of the ABCC8 gene did not demonstrate a significant effect on acute ischemic infarct size or 3-month functional outcome. Nonetheless, further studies with delayed imaging and more sensitive outcome measures remain warranted. </div> <a href="javascript:ShowArticleAbstract(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ABCC8-polymorphisms%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ABCC8-polymorphisms</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+stroke%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ischemic stroke</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22MRI-GENIE%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MRI-GENIE</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sulfonylurea-receptor-1%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sulfonylurea-receptor-1</a></li></ul> <a href="javascript:ShowArticleKeywords(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a 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Patient outcomes and health care resource utilization in acute pancreatitis-related central nervous system complications: insights from a national cohort study. <em class='incite-journal-name' onclick='ShowInCiteJournal(14272);'>J Int Med Res</em> 2025;<b>53</b>:3000605241311405. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39883809' target='_blank'>39883809</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11783543' target='_blank'>PMC11783543</a> DOI: <a href='https://dx.doi.org/10.1177/03000605241311405' target='_blank'>10.1177/03000605241311405</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1177/03000605241311405','39883809', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(18);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(18);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(18);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1177/03000605241311405' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(14272);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 12/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 02/01/2025]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv18" value="10.1177/03000605241311405" /> <div style="display: none" id="articleAbstract18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">OBJECTIVES</div><div class="abstract-content">Central nervous system complications of acute pancreatitis (AP) can result in cerebral edema (CE). We assessed the risk of serious outcomes and health care features associated with CE in patients hospitalized with AP. </div><div class="abstract-label">METHODS</div><div class="abstract-content">We conducted a retrospective cohort study using the National Inpatient Sample database. Patients were divided into the AP-CE group that developed CE and the AP-only group that did not. Outcome data were analyzed using Stata software. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Among 543,464 patients hospitalized with AP, 220 (0.04%) developed CE. In multivariate analysis, primary outcomes included increased length of hospital stay (adjusted odds ratio [aOR] 10.1; 95% confidence interval [CI] 0.50-19.70), hospital charges (aOR USD 208,713; 95% CI 27,095-390,330), and risk of death (aOR 17.17; 95% CI 5.88-50.07) in the AP-CE group. Secondary outcomes showed patients with AP-CE had a significantly increased risk of serious complications, particularly cardiac arrest (aOR 64.24; 95% CI 24.27-170.02), and higher hospital resource utilization. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">Patients with AP who develop CE face worse outcomes, including increased mortality risk, prolonged hospital stay, and greater resource utilization. Timely identification and effective management of CE in AP may reduce mortality and ease the health care burden associated with this neurological complication. </div> <a href="javascript:ShowArticleAbstract(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pancreatitis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pancreatitis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22blood%e2%80%93brain+disruption%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">blood–brain disruption</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22caregiver+burden%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">caregiver burden</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22central+nervous+system%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">central nervous system</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cerebral+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cerebral edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22health+care+resource+utilization%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">health care resource utilization</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22intracranial+pressure%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">intracranial pressure</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22pancreatic+encephalopathy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">pancreatic encephalopathy</a></li></ul> <a href="javascript:ShowArticleKeywords(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pancreatitis%2feconomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pancreatitis/economics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pancreatitis%2fmortality%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pancreatitis/mortality</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pancreatitis%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pancreatitis/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pancreatitis%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pancreatitis/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retrospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retrospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Length+of+Stay%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Length of Stay/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Patient+Acceptance+of+Health+Care%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Patient Acceptance of Health Care/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Health+Resources%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Health Resources/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Health+Resources%2feconomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Health Resources/economics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+Disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute Disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hospitalization%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hospitalization/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hospitalization%2feconomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hospitalization/economics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Databases%2c+Factual%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Databases, Factual</a></li></ul> <a href="javascript:ShowArticleMeSH(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(18);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow19"> <td style="min-width: 40px; text-align: center;"> 19 </td> <td> <div id="citation19" class="article-citation"> <b>Case N</b>, Coppler PJ, Mettenburg J, Ratay C, Tam J, Faiver L, Callaway C, Elmer J. Time-dependent association of grey-white ratio on early brain CT predicting outcomes after cardiac arrest at hospital discharge. <em class='incite-journal-name' onclick='ShowInCiteJournal(20344);'>Resuscitation</em> 2025;<b>206</b>:110440. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39592066' target='_blank'>39592066</a> DOI: <a href='https://dx.doi.org/10.1016/j.resuscitation.2024.110440' target='_blank'>10.1016/j.resuscitation.2024.110440</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.resuscitation.2024.110440','39592066', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(19);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(19);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(19);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1016/j.resuscitation.2024.110440' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(20344);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 10/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 11/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/20/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/28/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv19" value="10.1016/j.resuscitation.2024.110440" /> <div style="display: none" id="articleAbstract19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Cerebral edema after cardiac arrest can be quantified by the ratio of grey matter to white matter radiodensity (GWR) on computed tomography (CT). Severe edema predicts worse outcomes. We hypothesized the sensitivity and false positive rate of GWR predicting outcomes change over the first 24 hours post-arrest. </div><div class="abstract-label">METHODS</div><div class="abstract-content">We performed a single-center retrospective cohort study including patients resuscitated from cardiac arrest between January 2010 and December 2023 who were unresponsive to verbal commands. We excluded patients who arrested from a primary traumatic or neurological etiology and those without brain imaging within 24 hours of arrest. We divided patients into groups based on time from arrest to CT, then quantified the performance of GWR dichotomized at <1.10 and <1.20, predicting in-hospital mortality and death by neurologic criteria (DNC). </div><div class="abstract-label">RESULTS</div><div class="abstract-content">We included 2,204 patients with mean age 59 (SD 16) years. Overall, 1651 (75%) died in the hospital, of whom 248 (11%) progressed to DNC. Sensitivity of GWR <1.10 and GWR <1.20 for predicting in-hospital mortality increased over the first four hours post-arrest, reaching a maximum of 25% after five hours, while false positive rates remained <5% at all time points. Similar temporal trends were observed with DNC, although absolute values of sensitivity and false positive rate (FPR) varied. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">The sensitivity and FPR of early GWR predicting in-hospital mortality and DNC after resuscitation from cardiac arrest varies over the initial post-arrest period. Reduced GWR on brain CTs is most sensitive for in-hospital mortality when obtained more than four hours post-arrest and for DNC when obtained between four and five hours. However, FPR remained execellent throughout, making early reductions in GWR a specific marker of poor outcome regardless of timing. While brain CTs obtained within the first 24 hours post-arrest may be indicated to evaluate for neurologic etiologies of arrest, they may be less informative as an independent marker of prognosis. </div> <a href="javascript:ShowArticleAbstract(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anoxic+brain+injury%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anoxic brain injury</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+death%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain death</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cardiac+arrest%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cardiac arrest</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Computed+tomography%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Computed tomography</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heart+arrest%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heart arrest</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypoxia%2c+brain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypoxia, brain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypoxia%e2%80%93ischemia%2c+brain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypoxia–ischemia, brain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypoxic-ischemic+brain+injury%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypoxic-ischemic brain injury</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Outcome+prediction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Outcome prediction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prognosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prognosis</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Predictive+Value+of+Tests%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Predictive Value of Tests</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prognosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prognosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22White%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">White</a></li></ul> <a href="javascript:ShowArticleMeSH(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(19);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow20"> <td style="min-width: 40px; text-align: center;"> 20 </td> <td> <div id="citation20" class="article-citation"> <b>Puy L</b>, Kuchcinski G, Leboullenger C, Auger F, Cordonnier C, Bérézowski V. Multimodal and serial MRI monitors brain peri-hematomal injury and repair mechanisms after experimental intracerebral hemorrhage. <em class='incite-journal-name' onclick='ShowInCiteJournal(169693);'>J Cereb Blood Flow Metab</em> 2025;<b>45</b>:140-152. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39113403' target='_blank'>39113403</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571976' target='_blank'>PMC11571976</a> DOI: <a href='https://dx.doi.org/10.1177/0271678x241270198' target='_blank'>10.1177/0271678x241270198</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1177/0271678x241270198','39113403', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(20);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(20);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(20);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1177/0271678x241270198' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169693);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://mc.manuscriptcentral.com/jcbfm' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 01/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 05/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/20/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv20" value="10.1177/0271678x241270198" /> <div style="display: none" id="articleAbstract20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The peri-hematomal area (PHA) emerges as a key but puzzling interface where edematous and neuroinflammatory events co-occur after intracerebral hemorrhage (ICH), while being considered either as deleterious or protective. We aimed at unraveling the pathogeny and natural history of PHA over time after experimental ICH. Male and female rats were longitudinally followed up to day 7 using multimodal brain MRI. MRI measures were compared to neuropathological and behavioural results. While the peak of PHA volume at day 3 was predictive for spontaneous locomotor deficit without sex-effect, its drop at day 7 fitted with locomotor recovery and hematoma resorption. The PHA highest water density was observed at onset despite microvascular hypoperfusion, taken over by blood-brain barrier (BBB) leakage at day 3. Water density dropped at day 7, when vascular integrity was normalized, and the highest number of reactive astrocytes, microglial cells, and siderophages found. This study shows that the PHA with edematous component is hematoma-driven at onset and BBB-driven at day 3, but this excess neuroinflammation enabled PHA volume reduction and significant hematoma resorption as soon as day 7. Therapeutic interventions should consider this pathogeny, and be monitored by multimodal MRI in preclinical ICH models. </div> <a href="javascript:ShowArticleAbstract(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cerebral+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cerebral edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22MRI%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MRI</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22intracerebral+hemorrhage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">intracerebral hemorrhage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22neuroinflammation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">neuroinflammation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22rodent+model%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">rodent model</a></li></ul> <a href="javascript:ShowArticleKeywords(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cerebral+Hemorrhage%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cerebral Hemorrhage/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cerebral+Hemorrhage%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cerebral Hemorrhage/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Magnetic+Resonance+Imaging%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Magnetic Resonance Imaging/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Blood-Brain+Barrier%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Blood-Brain Barrier/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Blood-Brain+Barrier%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Blood-Brain Barrier/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hematoma%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hematoma/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li></ul> <a href="javascript:ShowArticleMeSH(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(20);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow21"> <td style="min-width: 40px; text-align: center;"> 21 </td> <td> <div id="citation21" class="article-citation"> <b>Stafford R</b>, Chatzidakis S, Kim ISY, Zhang Y, Rina A, Brush B, Mian A, Abdalkader M, Greer DM, Smirnakis SM, Feske SK, Dupuis J, Ong CJ. Follow-up ASPECTS improves prediction of potentially lethal malignant edema in patients with large middle cerebral artery stroke. <em class='incite-journal-name' onclick='ShowInCiteJournal(14700);'>J Neurointerv Surg</em> 2024;<b>17</b>:e83-e86. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38160055' target='_blank'>38160055</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11214636' target='_blank'>PMC11214636</a> DOI: <a href='https://dx.doi.org/10.1136/jnis-2023-021145' target='_blank'>10.1136/jnis-2023-021145</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1136/jnis-2023-021145','38160055', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(21);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(21);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(21);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(21);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1136/jnis-2023-021145' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(14700);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 10/17/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 12/05/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 01/03/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv21" value="10.1136/jnis-2023-021145" /> <div style="display: none" id="articleAbstract21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Recent studies have shown that follow-up head CT is a strong predictor of functional outcomes in patients with middle cerebral artery stroke and mechanical thrombectomy. We sought to determine whether total and/or regional follow-up Alberta Stroke Program Early CT Score (ASPECTSfu) are associated with important clinical outcomes during hospitalization and improve the performance of clinical prediction models of potentially lethal malignant edema (PLME). </div><div class="abstract-label">METHODS</div><div class="abstract-content">We conducted a retrospective study of patients at three medical centers in a major North American metropolitan area with baseline and follow-up head CTs after large middle cerebral artery stroke between 2006 and 2022. We used multivariable logistic regression to test the association of total and regional ASPECTSfu with PLME (cerebral edema related death or surgery), adjusting for total baseline ASPECTS, age, sex, admission glucose, tissue plasminogen activator, and mechanical thrombectomy. We compared existing clinical risk models with and without total or regional ASPECTSfu using area under the curve. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">In our 560 patient cohort, lower total ASPECTSfu was significantly associated with higher odds of PLME when adjusting for confounders (OR 1.69, 95% CI 1.49 to 2.0), and improved model discrimination compared with existing models and models using baseline ASPECTS. Deep territory involvement (OR 2.46, 95% CI 1.53 to 4.01) and anterior territory involvement (OR 3.23, 95% CI 1.88 to 5.71) were significantly associated with PLME. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">Lower ASPECTSfu and certain locations on regional ASPECTSfu, including deep and anterior areas, were significantly associated with PLME. Including ASPECTSfu information improved discrimination of established edema prediction models and could be used immediately to help facilitate clinical management decisions and prognostication. </div> <a href="javascript:ShowArticleAbstract(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CT%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">CT</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stroke%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stroke</a></li></ul> <a href="javascript:ShowArticleKeywords(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retrospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retrospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infarction%2c+Middle+Cerebral+Artery%2fdiagnostic+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infarction, Middle Cerebral Artery/diagnostic imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Follow-Up+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Follow-Up Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tomography%2c+X-Ray+Computed%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tomography, X-Ray Computed</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thrombectomy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thrombectomy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%2c+80+and+over%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged, 80 and over</a></li></ul> <a href="javascript:ShowArticleMeSH(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NINDS+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">K23 NS116033 NINDS NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(21);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow22"> <td style="min-width: 40px; text-align: center;"> 22 </td> <td> <div id="citation22" class="article-citation"> <b>Wang J</b>, Liu Q, Hu F, Zheng H, Jiang X, Chen L, Zhou M, Guo J, Chen H, Guo F, Tang Y, Li J, Zhou D, He L. Characteristics of Mortality After Endovascular Thrombectomy in Patients with Acute Ischemic Stroke. <em class='incite-journal-name' onclick='ShowInCiteJournal(6642);'>Clin Interv Aging</em> 2024;<b>19</b>:2145-2155. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39712632' target='_blank'>39712632</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662908' target='_blank'>PMC11662908</a> DOI: <a href='https://dx.doi.org/10.2147/cia.s496733' target='_blank'>10.2147/cia.s496733</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.2147/cia.s496733','39712632', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(22);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(22);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(22);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.2147/cia.s496733' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rcastoragev2.blob.core.windows.net/cc63f78d80efd0685711e99e299dc131/cia-19-2145.PMC11662908.pdf' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.2147/cia.s496733');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(6642);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 09/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 12/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 12/24/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv22" value="10.2147/cia.s496733" /> <div style="display: none" id="articleAbstract22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">Purpose</div><div class="abstract-content">Despite significant advancements in the treatment of acute ischemic stroke (AIS) with endovascular thrombectomy (EVT), post-EVT mortality remains a considerable concern. However, there is a lack of real-world epidemiological data delineating the characteristics of mortality for EVT, particularly in recent years following the widespread promotion of EVT treatment for stroke patients. </div><div class="abstract-label">Methods</div><div class="abstract-content">This multicenter, retrospective study collected data from 721 AIS patients who died following EVT across 33 hospitals in Sichuan Province, China, from January 2019 to September 2022. The analysis sought to identify the primary causes of death within 30 days post-EVT and explore their related clinical features. </div><div class="abstract-label">Results</div><div class="abstract-content">The leading causes of death were malignant cerebral edema (MCE) in 365 patients (50.6%), pneumonia in 180 patients (25%), and symptomatic intracranial hemorrhage (sICH) in 94 patients (13%). MCE was the predominant cause of death in anterior circulation strokes, while pneumonia prevailed in posterior circulation strokes. MCE was also the primary cause of death within one week post-EVT, but pneumonia became increasingly dominant over time. Large vessel occlusion and lower reperfusion success rate were significantly correlated with MCE. Advanced age increases the risk of death from pneumonia. Tandem occlusion and procedural complications tend to correlate with mortality from sICH. </div><div class="abstract-label">Conclusion</div><div class="abstract-content">This study revealed that the principal causes of death after EVT included MCE, sICH, and pneumonia. MCE was found to be correlated with unsuccessful reperfusion. sICH was associated with procedural complications and the operators' experience. Pneumonia was linked to post-EVT management, particularly for those who survived for one week. </div> <a href="javascript:ShowArticleAbstract(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22acute+ischemic+stroke%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">acute ischemic stroke</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cerebral+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cerebral edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22endovascular+thrombectomy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">endovascular thrombectomy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22intracranial+hemorrhage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">intracranial hemorrhage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22mortality%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">mortality</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22pneumonia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">pneumonia</a></li></ul> <a href="javascript:ShowArticleKeywords(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Thrombectomy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Thrombectomy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ischemic+Stroke%2fmortality%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intracranial+Hemorrhages%2fmortality%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intracranial Hemorrhages/mortality</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intracranial+Hemorrhages%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intracranial Hemorrhages/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intracranial+Hemorrhages%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intracranial Hemorrhages/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Complications%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Complications/epidemiology</a></li></ul> <a href="javascript:ShowArticleMeSH(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(22);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow23"> <td style="min-width: 40px; text-align: center;"> 23 </td> <td> <div id="citation23" class="article-citation"> <b>Sun X</b>, Xu S, Wang J, Li X, Sun H, Zhao W. Long-term hypothermia amplified neuroprotection by antagonizing intracranial pressure rebound after severe traumatic brain injury in rats. <em class='incite-journal-name' onclick='ShowInCiteJournal(17747);'>Neuroreport</em> 2024;<b>35</b>:1107-1116. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39423323' target='_blank'>39423323</a> DOI: <a href='https://dx.doi.org/10.1097/wnr.0000000000002106' target='_blank'>10.1097/wnr.0000000000002106</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1097/wnr.0000000000002106','39423323', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(23);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(23);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1097/wnr.0000000000002106' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17747);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/21/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv23" value="10.1097/wnr.0000000000002106" /> <div style="display: none" id="articleAbstract23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Long-term hypothermia has been reported to prevent intracranial pressure (ICP) rebound in clinical patients, but the duration for hypothermia and the corresponding ICP data are not available. This study investigated the optimal duration of long-term hypothermia in traumatic brain injury (TBI) rats, and observed the effect on ICP and neurological function. In this study, we established a rat severe TBI model with electronic Controlled Cortical Injury device, and implemented hypothermia (33 °C) for different durations. The motor function of the rats in each group was evaluated by beam walking test and inclined-grid climbing test, brain water content was calculated by the wet-dry weight method, Evan's blue staining was used to measure the blood-brain barrier (BBB) permeability, the change of hippocampal neurons was observed by Nissl staining, the expressions of BrdU, NeuN, and CD86 positive cells were detected by immunofluorescence staining, and the expressions of Bcl-2, Bax, iNOS, IL-10, and Arg-1 were detected by Western blot. We found that therapeutic hypothermia improved neurological recovery after TBI with declining ICP, reducing brain edema, decreasing BBB permeability, promoting neurogenesis, inhibiting apoptosis, and regulating inflammation. Moreover, 48 h hypothermia amplified the neuroprotective effect after injury on the basis of 4 or 24 h hypothermic treatment. Both 4 and 24 h hypothermia led to ICP rebound during or after rewarming, whereas 48 h hypothermia completely abolished ICP rebound. Our study suggests that long-term hypothermia amplifies neuroprotection after TBI by antagonizing ICP rebound. </div> <a href="javascript:ShowArticleAbstract(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <a href="javascript:ShowArticleKeywords(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Injuries%2c+Traumatic%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Injuries, Traumatic/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Injuries%2c+Traumatic%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Injuries, Traumatic/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Injuries%2c+Traumatic%2fphysiopathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Injuries, Traumatic/physiopathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Injuries%2c+Traumatic%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Injuries, Traumatic/therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypothermia%2c+Induced%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypothermia, Induced/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fprevention+%26amp%3b+control%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/prevention & control</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Time+Factors%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Time Factors</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intracranial+Hypertension%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intracranial Hypertension/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intracranial+Hypertension%2fprevention+%26amp%3b+control%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intracranial Hypertension/prevention & control</a></li></ul> <a href="javascript:ShowArticleMeSH(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(23);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow24"> <td style="min-width: 40px; text-align: center;"> 24 </td> <td> <div id="citation24" class="article-citation"> <b>Peng W</b>, Ma H, Zhao R, Xu S, Lv M, Jing B, Hu Z. Role of intermittent hypoxic training combined with methazolamide in the prevention of high-altitude cerebral edema in rats. <em class='incite-journal-name' onclick='ShowInCiteJournal(20954);'>Sci Rep</em> 2024;<b>14</b>:30252. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39632926' target='_blank'>39632926</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11618614' target='_blank'>PMC11618614</a> DOI: <a href='https://dx.doi.org/10.1038/s41598-024-81226-z' target='_blank'>10.1038/s41598-024-81226-z</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1038/s41598-024-81226-z','39632926', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(24);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(24);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(24);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(24);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1038/s41598-024-81226-z' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(20954);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 12/07/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv24" value="10.1038/s41598-024-81226-z" /> <div style="display: none" id="articleAbstract24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Although intermittent hypoxia training (IHT) and methazolamide (MTZ) alone can prevent high-altitude cerebral edema (HACE) to varying degrees, their efficacy and dispersion remain limited. However, only a handful of trials have explored the effectiveness of the IHT and MTZ combination in preventing HACE. Rats were first exposed to hypobaric hypoxia (5000 m, 54.02 kPa, 10.8% fraction of inspired oxygen (FiO2)) with simultaneous exhaustive exercise (EE) for different durations to determine the ideal condition for establishing a rat model of HACE. Rats receiving various courses of IHT were subjected to this condition, and changes in behaviour, brain water content (BWC), pathology and brain protein expression were evaluated. Meanwhile, rats received different doses of MTZ before and during hypoxia exposure with simultaneous EE. Finally, rats receiving the IHT and MTZ combination were then exposed to hypoxia with simultaneous EE. Systemic inflammation and mild cerebral edema developed in rats after 6 h of hypobaric hypoxia with simultaneous EE. Rats showed severe impairment of spatial and memory functions after 2 days of hypobaric hypoxia with simultaneous EE, and the pathology of their brain showed significant dilated perivascular spaces, cell swelling, vacuolar degeneration and reduced neuron count. BWC, serum inflammatory factors and expression of vascular endothelial growth factor (VEGF) and aquaporin 4 (AQP4) proteins in the hippocampus increased significantly. Both IHT and MTZ differentially counteracted hypobaric hypoxia-induced spatial and memory function impairments and increased BWC, pathological changes and expression of AQP4 and VEGF proteins in the hippocampus. Among these, the long-course IHT (BID, 14 d) combined with MTZ (200 mg/kg/d) showed the most significant improvement, restoring the rats' indices to normal levels. Continuous hypobaric hypoxia with simultaneous EE for 2 days resulted in significant HACE in rats, which may be used to establish a rat model of HACE. Both IHT and MTZ alleviated HACE in rats to varying degrees, among which long-course IHT (BID, 14 d) combined with MTZ (200 mg/kg/d) effectively prevented HACE in rats. </div> <a href="javascript:ShowArticleAbstract(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+mountain+sickness%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute mountain sickness</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22High-altitude+cerebral+edema%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">High-altitude cerebral edema</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypobaric+hypoxia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypobaric hypoxia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intermittent+hypoxia+training%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intermittent hypoxia training</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Methazolamide%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Methazolamide</a></li></ul> <a href="javascript:ShowArticleKeywords(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fprevention+%26amp%3b+control%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/prevention & control</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain+Edema%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain Edema/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Altitude+Sickness%2fprevention+%26amp%3b+control%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Altitude Sickness/prevention & control</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Altitude+Sickness%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Altitude Sickness/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Altitude+Sickness%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Altitude Sickness/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Physical+Conditioning%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Physical Conditioning, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypoxia%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypoxia/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Methazolamide%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Methazolamide/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aquaporin+4%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aquaporin 4/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vascular+Endothelial+Growth+Factor+A%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vascular Endothelial Growth Factor A/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Altitude%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Altitude</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/pathology</a></li></ul> <a href="javascript:ShowArticleMeSH(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22National+Natural+Science+Foundation+of+China+(NSFC)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">82171858 National Natural Science Foundation of China (NSFC)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Science+and+Technology+Research+and+Development+Program+of+China+National+Railway+Group+Co.%2c+Ltd%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">K2019Z005 Science and Technology Research and Development Program of China National Railway Group Co., Ltd</a></li></ul> <a href="javascript:ShowArticleGrant(24);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow25"> <td style="min-width: 40px; text-align: center;"> 25 </td> <td> <div id="citation25" class="article-citation"> <b>Sheth KN</b>, Albers GW, Saver JL, Campbell BCV, Molyneaux BJ, Hinson HE, Cordonnier C, Steiner T, Toyoda K, Wintermark M, Littauer R, Collins J, Lucas N, Nogueira RG, Simard JM, Wald M, Dawson K, Kimberly WT. Intravenous glibenclamide for cerebral oedema after large hemispheric stroke (CHARM): a phase 3, double-blind, placebo-controlled, randomised trial. <em class='incite-journal-name' onclick='ShowInCiteJournal(15923);'>Lancet Neurol</em> 2024;<b>23</b>:1205-1213. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39577921' target='_blank'>39577921</a> DOI: <a href='https://dx.doi.org/10.1016/s1474-4422(24)00425-3' target='_blank'>10.1016/s1474-4422(24)00425-3</a>]<span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.referencecitationanalysis.com/citearticles?term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22c%22%2c%22o%22%3anull%2c%22v%22%3a%2210.1016%2fs1474-4422(24)00425-3%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d' target='_blank'>Citation(s) in <i>RCA</i>: 1</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInflu('10.1016%2fs1474-4422(24)00425-3')">Impact Index Per Article: 1.0</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/s1474-4422(24)00425-3','39577921', 'Brain Edema/etiology')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(25);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(25);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://doi.org/10.1016/s1474-4422(24)00425-3' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(15923);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/24/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv25" value="10.1016/s1474-4422(24)00425-3" /> <div style="display: none" id="articleAbstract25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">No treatment is available to prevent brain oedema, which can occur after a large hemispheric infarction. Glibenclamide has previously been shown to improve functional outcome and reduce neurological or oedema-related death in patients younger than 70 years who were at risk of brain oedema after an acute ischaemic stroke. We aimed to assess whether intravenous glibenclamide could improve functional outcome at 90 days in patients with large hemispheric infarction. </div><div class="abstract-label">METHODS</div><div class="abstract-content">CHARM was a phase 3, double-blind, placebo-controlled, randomised trial conducted across 143 acute stroke centres in 21 countries. We included patients aged 18-85 years with a large stroke, defined either by an Alberta Stroke Program Early CT Score (ASPECTS) of 1-5 or by an ischaemic core lesion volume of 80-300 mL on CT perfusion or MRI diffusion-weighted imaging. Patients were randomly assigned in a 1:1 ratio to either intravenous glibenclamide (8·6 mg over 72 h) or placebo. The study drug was started within 10 h of stroke onset. The primary efficacy outcome was the shift in the distribution of scores on the modified Rankin Scale at day 90, as a measure of functional outcome. The primary efficacy outcome was analysed in a modified intention-to-treat population, which included all randomly assigned patients aged 18-70 years. The safety population comprised all randomly assigned patients who received a dose. This trial is registered with ClinicalTrials.gov (NCT02864953). The trial was stopped early by the sponsor for strategic and operational reasons (slow enrolment because of COVID-19), before any unblinding or knowledge of the trial results. </div><div class="abstract-label">FINDINGS</div><div class="abstract-content">Between Aug 29, 2018, and May 23, 2023, 535 patients were enrolled and randomly assigned, of whom 518 received a dose (safety population) and 431 were aged 18-70 years and comprised the modified intention-to-treat population (217 were assigned glibenclamide and 214 placebo). The mean age of patients was 58·7 (SD 9·0) years in the placebo group and 58·0 (9·5) years in the glibenclamide group; the median US National Institutes of Health Stroke Scale (NIHSS) score was 19 (IQR 16-23) in the placebo group and 19 (IQR 16-22) in the glibenclamide group; and the mean time from stroke onset to study drug start was 8·9 h (SD 2·1) in the placebo group and 9·2 h (2·1) in the glibenclamide group. Intravenous glibenclamide was not associated with a favourable shift in the modified Rankin scale at 90 days (common odds ratio [OR] 1·17 [95% CI 0·80-1·71], p=0·42). 90-day mortality was 29% (61 of 214) in the placebo group and 32% (70 of 217) in the glibenclamide group (hazard ratio 1·20 [0·85-1·70]; p=0·30). Serious adverse events in the prespecified safety population were consistent with the known safety profile of glibenclamide and included hypoglycaemia in 15 (6%) of 259 patients in the glibenclamide group and in four (2%) of 259 patients in the placebo group, leading to dose interruption or reduction in seven (3%) patients in the glibenclamide group and in one (<1%) in the placebo group. </div><div class="abstract-label">INTERPRETATION</div><div class="abstract-content">Intravenous glibenclamide did not improve functional outcome in patients aged 18-70 years after large hemispheric infarction, although the trial was underpowered to make definitive conclusions because it was stopped early. Future prospective evaluation could be warranted to identify a possible benefit of intravenous glibenclamide in specific subgroups. </div><div class="abstract-label">FUNDING</div><div class="abstract-content">Biogen. </div> <a href="javascript:ShowArticleAbstract(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <a href="javascript:ShowArticleKeywords(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a 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id="RootHolder_userIndexComputePopup_InfluenceIndexTitle3">Article Influence Index</span><sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="RootHolder_userIndexComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_userIndexComputePopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_userIndexComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1286575841" type="text/javascript">  </script> <div id="RootHolder_articleExportPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:280px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow" style="font-size:11pt;"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_articleExportPopup_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Export Articles to File</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="dxtcLite_MetropolisBlue dxtcSys dxtc-init dxtc-top dxtc-pc" id="RootHolder_articleExportPopup_ExportFilePageControl" style="width:100%;"> <ul class="dxtc-strip dxtc-row dxtc-stripContainer"> <li class="dxtc-leftIndent"> </li><li class="dxtc-tab dxtc-lead" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-activeTab dxtc-lead"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-spacer"> </li><li class="dxtc-tab dxtc-last"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-activeTab dxtc-last" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-rightIndent"> </li> </ul><div class="dxtc-content"> <div> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_SearchTermText1">Brain Edema/etiology (4206 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:5px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_1662381219" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailEndIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_616434442" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_1167331127" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_54524200" type="text/javascript">  </script><script id="dxss_1678130197" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" style="font-weight:bold;">JCR Year:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" type="hidden" value="2023" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" value="2023" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2023</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2022</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2021</td> </tr> </table> </div></td> </tr> </table><script id="dxss_830317689" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_167955898" type="text/javascript">  </script><script id="dxss_2013408041" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1062639383" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_104403608" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1973673553" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_6" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLTSys dxflItemSys dxflCheckBoxWithTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" style="font-weight:bold;">Record Content:</label></td> </tr><tr> <td class="dxflNestedControlCell_MetropolisBlue"> <table> <tr> <td style="vertical-align: middle; padding: 5px;"> <table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields" style="color:#BD4100;"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$cbSelectAllFields" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label>Select All Fields</label></td> </tr> </table><script id="dxss_1176833720" type="text/javascript">  </script> </td> </tr> <tr> <td style="padding: 5px;"> <table class="dxeCheckBoxList_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields" style="width:100%;border-collapse:separate;"> <tr> <td class="dxe"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields" /><table style="width:100%;"> <tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB0" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Author(s)</label></td> </tr> </table><script id="dxss_771536870" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB1" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Title</label></td> </tr> </table><script id="dxss_1086331335" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB2" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Keywords</label></td> </tr> </table><script id="dxss_1308541020" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB3" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">MESH Headings</label></td> </tr> </table><script id="dxss_896786043" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB4" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Journal Title</label></td> </tr> </table><script id="dxss_450242410" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB5" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Year</label></td> </tr> </table><script id="dxss_765036875" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB6" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Type</label></td> </tr> </table><script id="dxss_1629835480" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB7" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Language</label></td> </tr> </table><script id="dxss_1218080503" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB8" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Published Date</label></td> </tr> </table><script id="dxss_1428514578" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB9" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author</label></td> </tr> </table><script id="dxss_1113720113" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB10" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author’s Affiliations</label></td> </tr> </table><script id="dxss_310841941" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB11" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author</label></td> </tr> </table><script id="dxss_1301541094" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB12" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author’s Affiliations</label></td> </tr> </table><script id="dxss_675718561" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB13" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Email</label></td> </tr> </table><script id="dxss_2006865700" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB14" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">All Authors's Affiliations</label></td> </tr> </table><script id="dxss_1204905793" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB15" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Grant</label></td> </tr> </table><script id="dxss_407477242" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB16" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">ISSN</label></td> </tr> </table><script id="dxss_218345291" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB17" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Publisher</label></td> </tr> </table><script id="dxss_1394037744" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB18" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexing / Abstracting</label></td> </tr> </table><script id="dxss_319681069" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB19" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Factor</label></td> </tr> </table><script id="dxss_1292701966" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB20" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">JCR Quartile</label></td> </tr> </table><script id="dxss_1844280938" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB21" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Index Per Article</label></td> </tr> </table><script id="dxss_838303323" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB22" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Category</label></td> </tr> </table><script id="dxss_1464125856" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB23" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Times Cited in RCA</label></td> </tr> </table><script id="dxss_148257179" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB24" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Peer-Reviewed Journal</label></td> </tr> </table><script id="dxss_950217086" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB25" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Open Access</label></td> </tr> </table><script id="dxss_1732367175" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB26" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">DOI</label></td> </tr> </table><script id="dxss_1936777588" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB27" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">PMID</label></td> </tr> </table><script id="dxss_745806673" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB28" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Citation</label></td> </tr> </table><script id="dxss_1835441810" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB29" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexed in RCA</label></td> </tr> </table><script id="dxss_847142451" type="text/javascript">  </script></td><td></td><td></td> </tr> </table></td> </tr> </table><script id="dxss_1169734383" type="text/javascript">  </script> </td> </tr> </table> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_7" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportedDetailFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_1198171345" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_1960175520" type="text/javascript">  </script> </div> </div><div style="display:none;"> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_SearchTermText2">Brain Edema/etiology (4206 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:10px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_814491935" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportEndSIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" value="600" type="text" /></td> </tr> </table><script id="dxss_1331245653" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:10px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_2046065225" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_1926633208" type="text/javascript">  </script><script id="dxss_228619664" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:20px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" type="hidden" value="1" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" value="Excel" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1509722775" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_960798088" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_835950349" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportedFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_308093146" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_424125632" type="text/javascript">  </script> </div> </div> </div> </div><b class="dx-clear"></b><table id="RootHolder_articleExportPopup_ExportFilePageControl_LP" class="dxtcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_TL">Loading…</span></td> </tr> </table><script id="dxss_2124675053" type="text/javascript">  </script> </div> </div><div class="dxpc-footer"> <div class="popup-footer-button-container"> <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles" 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All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA </div> <div class="scroll"> <a href="#top" target="_self"> <img src="/Contents/Images/backtop3.png" /> </a> </div> <div id="categorySelectorPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Select the Category</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="categorySelectorPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="categorySelectorPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="categorySelectorPopup_TL">Loading…</span></td> </tr> </table><div id="categorySelectorPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_166253781" type="text/javascript">  </script> <div id="pcLoginPopUp_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:700px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="pcLoginPopUp_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="pcLoginPopUp_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="pcLoginPopUp_TL">Loading…</span></td> </tr> </table><div id="pcLoginPopUp_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_430910140" type="text/javascript">  </script> <div id="aiComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:300px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Impact Index Per Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for Impact Index Per Article</b> </p> <p> Times Cited ÷ Number of Years = Impact Index Per Article<sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="aiComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="aiComputePopup_TL">Loading…</span></td> </tr> </table><div id="aiComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_698179129" type="text/javascript">  </script> <script type="text/javascript"> //<![CDATA[ var callBackFrameUrl='/WebResource.axd?d=beToSAE3vdsL1QUQUxjWdX-3aFLejnBliGvqSCZYULGFdxZmRlcJcqs71AKVNTQEXljNmd0slFkUZ_AFaCke4Q2&t=638628207619783110'; WebForm_InitCallback();//]]> </script> </form> </body> </html>