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fa-dropdown desktop-hidden"></i> </a></li></ul></div></div></div></div></div></div></div></header></div><div class="main-wrapper"><div class="main-container"><div class="page-wrapper"><div class="sections-container"><div id="page-header"><div class="remove-menu-padding remove-menu-padding-mobile header-wrapper header-uncode-block"><div data-parent="true" class="vc_row row-container with-kburns with-parallax" id="row-unique-0"><div class="row-background background-element"><div class="background-wrapper"><div class="background-inner srcset-bg" style="background-image: url(https://liondx.com/wp-content/uploads/2023/06/Soreveglianza-candida-auris.jpeg);background-repeat: no-repeat;background-position: center center;background-size: cover;"></div><div class="block-bg-overlay block-bg-blend-mode for-ie style-color-384205-bg" style="opacity: 1;"></div><div class="block-bg-overlay block-bg-blend-mode not-ie style-color-384205-bg" style="mix-blend-mode:multiply;"></div></div></div><div class="row single-top-padding single-bottom-padding triple-h-padding full-width row-parent row-header" data-height-ratio="70"><div class="wpb_row row-inner"><div class="wpb_column pos-middle pos-center align_left column_parent col-lg-12 single-internal-gutter"><div class="uncol style-dark" ><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ><div class="vc_row row-internal row-container"><div class="row row-next-to-blend row-child"><div class="wpb_row row-inner"><div class="wpb_column pos-middle pos-center align_left column_child col-lg-12 single-internal-gutter"><div class="uncol style-dark" ><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ><div class="empty-space empty-half" ><span class="empty-space-inner"></span></div><div class="vc_custom_heading_wrap "><div class="heading-text el-text bottom-t-top animate_when_almost_visible" data-delay="400"><h5 class="h5 fontspace-210350" ><span><a href="https://liondx.com/funghi-real-time-pcr/">FUNGHI: REAL TIME PCR</a></span></h5></div><div class="clear"></div></div><div class="vc_custom_heading_wrap "><div class="heading-text el-text" ><h1 class="font-weight-400" ><i><span>Candida auris</span></i></h1></div><div class="clear"></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div><script id="script-row-unique-0" data-row="script-row-unique-0" type="text/javascript" class="vc_controls">UNCODE.initRow(document.getElementById("row-unique-0"));</script></div></div></div></div></div><article id="post-103137" class="page-body style-color-xsdn-bg post-103137 post type-post status-publish format-standard hentry category-prodotti"><div class="post-wrapper"><div class="post-body"><div class="post-content un-no-sidebar-layout"><div data-parent="true" class="vc_row row-next-to-blend row-container onepage-section" data-label="neonatale" data-name="neonatale" id="row-unique-1"><div class="row double-top-padding single-bottom-padding triple-h-padding full-width row-parent"><div class="wpb_row row-inner"><div class="wpb_column pos-middle pos-left align_left column_parent col-lg-12 single-internal-gutter"><div class="uncol style-light" ><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ><div class="vc_row row-internal row-container"><div class="row row-child"><div class="wpb_row row-inner"><div class="wpb_column pos-top pos-left align_left column_child col-lg-12 single-internal-gutter"><div class="uncol style-light" ><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ><div class="vc_custom_heading_wrap "><div class="heading-text el-text left-t-right animate_when_almost_visible" data-delay="300"><h2 class="h2 text-accent-color" ><span><em>Auris</em>ID</span></h2></div><div class="clear"></div></div><div class="divider-wrapper left-t-right animate_when_almost_visible" data-delay="400" ><hr class="border-color-648163-color separator-no-padding" /></div></div></div></div></div></div></div></div></div></div></div></div></div></div><script id="script-row-unique-1" data-row="script-row-unique-1" type="text/javascript" class="vc_controls">UNCODE.initRow(document.getElementById("row-unique-1"));</script></div></div></div><div data-parent="true" class="vc_row row-container onepage-section" data-label="neonatale" data-name="neonatale" id="row-unique-2"><div class="row no-top-padding single-bottom-padding triple-h-padding full-width row-parent"><div class="wpb_row row-inner"><div class="wpb_column pos-middle pos-left align_left column_parent col-lg-12 single-internal-gutter"><div class="uncol style-light" ><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ><div class="vc_row row-internal row-container"><div class="row row-child"><div class="wpb_row row-inner"><div class="wpb_column pos-top pos-left align_left column_child col-lg-6 half-internal-gutter"><div class="uncol style-light animate_when_almost_visible bottom-t-top" data-delay="400"><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ><div class="vc_custom_heading_wrap "><div class="heading-text el-text" ><h3 class="fontheight-162334 font-weight-600 text-accent-color" ><span>L’unico test validato per lo screening di <em>Candida auris</em> su tamponi di sorveglianza, senza estrazione del DNA</span></h3></div><div class="clear"></div></div><div class="uncode_text_column" ><p><em>Auris</em>ID è un test <strong>Real-Time PCR marcato CE IVD per l’identificazione di <em>Candida auris</em> da:</strong></p><ul class="ul1"><li class="li1"><span class="s2"><b>tamponi di sorveglianza (ascellare / inguinale)<span class="Apple-converted-space"> </span></b></span></li><li class="li1"><span class="s2"><b>siero</b></span></li><li class="li1"><span class="s2"><b>plasma</b></span></li></ul><p><span class="s2">Attualmente risulta essere <b>l’unico test validato per lo screening su tamponi di sorveglianza</b>, senza la necessità di una fase di estrazione degli acidi nucleici, con una sensibilità analitica fino a 1 copia genoma/reazione.<span class="Apple-converted-space"> </span></span></p><p><span class="s2"><em>Auris</em>ID effettua lo screening su un <b>numero variabile di tamponi (da 1 a 94), in contemporanea,</b> <b>in meno di 1 ora</b>.<span class="Apple-converted-space"> </span></span></p><p><span class="s2">La possibilità di processare diverse matrici biologiche offre un maggiore range di applicabilità. <em>Auris</em>ID, infatti può essere usato:<br /> 1) per l’identificazione di sepsi (<b>da siero e plasma)</b>;<br /> 2) per programmi di sorveglianza della diffusione di <em>Candida auris</em> in ambiente nosocomiale (<b>da</b> <strong>t</strong><b>ampone di sorveglianza</b>);<br /> 3) per lo screening dei contatti diretti di soggetti positivi come indicato dal Ministero della Salute (<b>da</b> <strong>t</strong><b>ampone di sorveglianza</b>)<span class="Apple-converted-space"> </span></span></p><p><span class="s2">La facilità di esecuzione e la rapidità con la quale viene fornito il risultato garantiscono la <b>possibilità di gestione immediata del paziente in caso di positività</b>, riducendo il rischio di diffusione del lievito.<span class="Apple-converted-space"> </span></span></p><p><span class="s2"><strong>Il sistema è validato sui più comuni strumenti di Real-Time PCR</strong> presenti nei laboratori.</span></p></div><div class="uncode_text_column" ><p class="p1">Il test dimostra <b>sensibilità, specificità, NPV e PPV rispettivamente del 96,6%, 100%, 98,2% e 100%</b>, valori evidenziati nell’articolo Bayona et al., 2021 “Validation and implementation of a commercial Real-Time PCR assay for direct detection of <i>Candida auris</i> from surveillance samples”.<span class="Apple-converted-space"> </span></p></div><div class="uncode_text_column" ><ul class="ul1"><li class="li1"><span class="s2">Sensibilità <1 genoma di <em>Candida auris</em></span></li><li class="li1"><span class="s2">Rilevazione in un range di 6 ordini di grandezza (n° target da <1 a 10^6)</span></li><li class="li1"><span class="s2">Risultato in <1h senza estrazione del DNA.</span></li></ul></div></div></div></div></div></div><div class="wpb_column pos-top pos-center align_left column_child col-lg-6 single-internal-gutter"><div class="uncol style-light" ><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ><div class="uncode-single-media text-left"><div class="single-wrapper" style="max-width: 100%;"><div class="tmb tmb-light tmb-media-first tmb-media-last tmb-content-overlay tmb-no-bg"><div class="t-inside"><div class="t-entry-visual"><div class="t-entry-visual-tc"><div class="uncode-single-media-wrapper"><img decoding="async" class="srcset-async srcset-auto wp-image-103107" src="https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-scaled.jpg" width="2560" height="1386" alt="Candida auris" data-no-bp="" data-bp="720,1032" data-uniqueid="103107-203393" data-guid="https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-scaled.jpg" data-path="2023/07/Terapia-intensiva-rischio-Candida-auris-scaled.jpg" data-width="2560" data-height="1386" data-singlew="6" data-singleh="" data-crop="" loading="lazy" data-srcset="https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-scaled.jpg 2560w, https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-300x162.jpg 300w, https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-1024x554.jpg 1024w, https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-768x416.jpg 768w, https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-1536x831.jpg 1536w, https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-2048x1109.jpg 2048w, https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-350x189.jpg 350w, https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-scaled-uai-720x390.jpg 720w, https://liondx.com/wp-content/uploads/2023/07/Terapia-intensiva-rischio-Candida-auris-scaled-uai-1032x559.jpg 1032w" srcset="data:image/svg+xml;base64,PHN2ZyB3aWR0aD0iMjU2MCIgaGVpZ2h0PSIxMzg2IiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxwYXRoIGQ9Ik0wIDBoMXYxSDB6IiBmaWxsPSJub25lIiBmaWxsLXJ1bGU9ImV2ZW5vZGQiLz48L3N2Zz4="></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div><script id="script-row-unique-2" data-row="script-row-unique-2" type="text/javascript" class="vc_controls">UNCODE.initRow(document.getElementById("row-unique-2"));</script></div></div></div><div data-parent="true" class="vc_row style-color-lxmt-bg row-container onepage-section" data-label="neonatale" data-name="neonatale" id="row-unique-3"><div class="row double-top-padding double-bottom-padding triple-h-padding full-width row-parent"><div class="wpb_row row-inner"><div class="wpb_column pos-top pos-left align_left column_parent col-lg-6 single-internal-gutter"><div class="uncol style-light animate_when_almost_visible bottom-t-top" data-delay="300"><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ><div class="vc_custom_heading_wrap "><div class="heading-text el-text" ><h3 class="fontheight-162334 font-weight-600 text-accent-color" ><span>Sei pronto ad affrontare un caso di <em>Candida auris</em>?</span></h3></div><div class="clear"></div></div><div class="vc_custom_heading_wrap "><div class="heading-text el-text" ><h4 class="h4 fontheight-162334 font-weight-600 text-color-648163-color" ><span>Clicca sulle domande per ottenere le risposte</span></h4></div><div class="clear"></div></div><div class="uncode-accordion wpb_accordion wpb_content_element sign-size-rg w-border" data-collapsible="no" data-target="" data-active-tab="0" ><div class="panel-group wpb_wrapper wpb_accordion_wrapper" id="accordion_1097126682" role="tablist" aria-multiselectable="true" data-no-toggle=""><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1689846304933-15-6"><span>COS’È CANDIDA AURIS?</span></a></p></div><div id="1689846304933-15-6" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p class="p1">La <span class="s1"><i>Candida auris</i></span>, specie del genere <span class="s1"><i>Candida</i></span>, è un patogeno multi-resistente emergente a livello globale, causa di infezioni nosocomiali. Da quando è stato isolato per la prima volta, <span class="s1"><i>C. auris</i></span> è stato associato a infezioni del flusso sanguigno e delle ferite e ha causato epidemie ospedaliere in diversi paesi. <span class="s1"><i>C. auris</i></span> è comunemente resistente al fluconazolo, farmaco antimicotico di prima linea, e ne sono stati segnalati ceppi multiresistenti.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1682607896-1-9616894281727761689428277407"><span>Perché avviare un sistema di SORVEGLIANZA anche se nella tua struttura non si sono ancora verificati dei casi?</span></a></p></div><div id="1682607896-1-9616894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p class="p1">Perché la diffusione di ceppi resistenti del fungo <i>Candida auris</i> continua ad investire un numero sempre crescente di regioni italiane.<br /> E anche perché il fungo, come emanato dal Ministero della Salute: «è resistente ai trattamenti antimicotici di uso comune, inclusi azoli, echinocandine e polieni, e agli usuali prodotti antifungini per la pulizia delle superfici». Il fungo, infatti, costituisce un biofilm che lo rende poco suscettibile ai disinfettanti, dunque è particolarmente resistente sulle superfici.</p><p class="p1">Il MSAL dichiara che «è difficile da diagnosticare <i>Candida auris</i> mediante i metodi di laboratorio standard, che facilmente inducono a errori di identificazione e conseguente gestione inappropriata dei casi di infezione o colonizzazione» e il19 giugno 2023 emette linee guida molto precise per la gestione della sorveglianza di <em>Candida auris.</em></p><p class="p1"><a href="https://liondx.com/wp-content/uploads/2023/07/Sorveglianza-Candida-auris-Ministero-della-Salute.pdf" target="_blank" rel="noopener"><span class="s1">Vai alla Circolare del MSAL</span></a></p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1689846366145-16-3"><span>COSA CONSIGLIA DI FARE IL MINISTERO DELLA SALUTE?</span></a></p></div><div id="1689846366145-16-3" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p class="p1">«Il numero di casi di infezione/colonizzazione da <em>Candida auris</em> continua ad aumentare rapidamente in molti paesi. […] In Italia, nel periodo 1° luglio 2019 – 22 dicembre 2022 sono stati notificati allo scrivente Ministero 361 casi di infezione/colonizzazione (età mediana circa 64 anni, range 0–91, soprattutto maschi) da 17 strutture sanitarie in quattro regioni (Liguria 82%, Piemonte 13%, Emilia-Romagna 4%, Veneto 1 caso), di cui almeno 146 (40%) deceduti. Oltre il 90% dei casi erano colonizzati, almeno la metà presentavano comorbidità e almeno un terzo era SARS-CoV-2 positivo. Nello stesso periodo, altri casi di infezione/colonizzazione (almeno 206 casi) non sono stati notificati. Successivamente, sono stati notificati altri casi (circa 40), con l’interessamento anche di due Regioni che non avevano notificato casi in precedenza (Liguria, Piemonte, Lazio, Toscana). Si rappresenta, pertanto, un crescente rischio di trasmissione intraospedaliera, di possibile sviluppo di candidemia soprattutto in caso di colonizzazione simultanea multipla, e di diffusione comunitaria.</p><p class="p1">«[…] Pertanto, è opportuno identificare e sottoporre a screening i soggetti che hanno condiviso la stanza con un paziente infetto/colonizzato anche se questi sono stati dimessi dalla struttura.</p><p class="p1">«[…] Nei reparti critici in cui si continuano a registrare casi, è importante considerare l’opportunità di screening per il personale sanitario che vi è impegnato, per es. tramite coltura dell’impronta della mano su piastra agarizzata, oltre alle procedure di sanificazione ambientale ordinaria e straordinaria.</p><p class="p2">«[…] È indicato lo screening per <em>C. auris</em> al momento del ricovero nei soggetti con storia di degenza ospedaliera (di almeno una notte) o attività di riabilitazione, nei precedenti 12 mesi, in strutture di assistenza situate nelle regioni maggiormente interessate.»</p><p class="p1"><a style="text-decoration: underline;" href="https://liondx.com/wp-content/uploads/2023/07/Sorveglianza-Candida-auris-Ministero-della-Salute.pdf" target="_blank" rel="noopener"><span class="s1">Vai alla Circolare del MSAL</span></a></p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1682607896-2-3816894281727761689428277407"><span>Quali sono i vantaggi di un test molecolare rispetto a un test colturale?</span></a></p></div><div id="1682607896-2-3816894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p>2) Entrambi i test, se utilizzati correttamente, permettono l’identificazione di <em>Candida auris</em>. Rispetto a un test colturale, il cui risultato si ottiene dopo ~ 48 h, il test molecolare risulta molto più rapido.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1682608034443-2-216894281727761689428277407"><span>Qual è il metodo diagnostico più rapido ed efficace?</span></a></p></div><div id="1682608034443-2-216894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p>3) La Real-Time PCR è una metodica rapida, sensibile e specifica che permette di processare in breve tempo un ampio numero di campioni.<br /> <em>Auris</em>ID è un kit UNICO sul mercato. Ecco perché.<br /> È il più veloce e processivo: processa da 1 a 94 tamponi in 50 minuti;<br /> ha le migliori prestazioni: sensibilità, specificità, PPV, NPV ~ 100%;<br /> è l’unico da tamponi di sorveglianza (Copan) che non necessita di estrazione del DNA, validato e marcato CE-IVD.<br /> Data la sua elevata rapidità, <em>Auris</em>ID dà modo di mettere tempestivamente in atto tutte le misure per isolare il paziente colonizzato e per contenere la diffusione del fungo.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1682608063291-3-016894281727761689428277407"><span>Come si utilizza in laboratorio?</span></a></p></div><div id="1682608063291-3-016894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p>Il kit è compatibile con i tamponi eSwab Copan: si carica direttamente il liquido di trasporto del tampone nella mix di reazione, senza la necessità di una fase estrattiva. Questo permette di aumentare la processività del test riducendo i tempi di allestimento della seduta analitica. Il kit è compatibile con i più comuni strumenti di Real-Time. Grazie a questo si potranno sfruttare le risorse già esistenti nel tuo laboratorio. Nel caso in cui queste non fossero disponibili, LionDx può fornire strumenti in service.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1685626606884-11-1016894281727761689428277407"><span>Quali strumenti sono necessari per eseguire il test AurisID?</span></a></p></div><div id="1685626606884-11-1016894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p><strong><em>Auris</em></strong><strong>ID è un kit “aperto” in quanto è utilizzabile sui più comuni strumenti presenti nei laboratori. Ne citiamo solo alcuni. </strong></p><p>ESTRAZIONE: Qiagen EZ1, QiaSymphony, Qiagen QIAamp spin columns, Qiagen QiaCube, Roche MagnaPure e altri.</p><p>AMPLIFICAZIONE: ABI 7500, Qiagen RotorGene, BioRad CFX96, Illumina Eco, BMS MIC, Roche LC480 (II) e altri, Agilent AriaMx e altri.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1682611850270-4-516894281727761689428277407"><span>Come si interpreta il dato diagnostico?</span></a></p></div><div id="1682611850270-4-516894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p>Il protocollo si basa su 40 cicli di amplificazione, all’interno dei quali è possibile rilevare fino a <1copia/reazione. Il kit ha una specificità clinicamente provata del 100%, per cui se c’è amplificazione entro 40 cicli il test va interpretato come positivo.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1683104475231-5-516894281727761689428277407"><span>Come verificare se le superfici sono contaminate da Candida auris?</span></a></p></div><div id="1683104475231-5-516894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p>Grazie all’impiego del tampone, il kit <em>Auris</em>ID può aiutare a rilevare il DNA del fungo anche dalle superfici.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1683104569762-6-416894281727761689428277407"><span>Come procurarsi il miglior strumento diagnostico in emergenza?</span></a></p></div><div id="1683104569762-6-416894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p><em>Auris</em>ID è un kit altamente innovativo UNICO sul mercato (vedi punto 2). Dunque basterà richiedere a LionDx il “certificato di unicità” e procedere rapidamente con “trattativa diretta”.<br /> Nel caso in cui la tua struttura non possedesse uno strumento idoneo all’esecuzione di una Real-Time PCR, LionDx sarà lieta di fornirne uno in service.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1683104638917-7-216894281727761689428277407"><span>Il personale sanitario è stato formato?</span></a></p></div><div id="1683104638917-7-216894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p>LionDx, azienda specializzata in diagnostica fungina, mette a disposizione il proprio know-how nel caso in cui la tua struttura ne avesse bisogno. Inoltre, attraverso gli specialist, offre demo on-site oltre che “filo diretto” con i propri clienti per ogni necessità.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1683104696229-8-516894281727761689428277407"><span>Come fare un programma di PREVENZIONE contro Candida auris?</span></a></p></div><div id="1683104696229-8-516894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p>La sorveglianza è la miglior forma di prevenzione. Dal momento che la colonizzazione da parte di <em>Candida auris</em> è totalmente asintomatica e che il contagio avviene per contatto, è necessario effettuare lo screening di tutti i pazienti da ricoverare nei reparti ad alto rischio (come la terapia intensiva), così da evitare l’insorgenza di focolai. Nel caso in cui si riscontrasse la positività di un paziente, sarebbe necessario lo screening di tutte le persone entrate in contatto con il paziente colonizzato oltre che delle superfici ospedaliere potenzialmente contaminate (vedi punto 1).<br /> <em>Auris</em>ID è il kit perfetto per fare sorveglianza: dispone di 50 test utilizzabili singolarmente. L’attuale lotto scade a fine dicembre 2024.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1683104817048-9-016894281727761689428277407"><span>Quanto tempo dura un kit diagnostico prima di scadere?</span></a></p></div><div id="1683104817048-9-016894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p><em>Auris</em>ID è il kit perfetto per fare sorveglianza: dispone di 50 test utilizzabili singolarmente. L’attuale lotto scade a fine dicembre 2024.<br /> Dunque, se lo acquisti oggi hai quasi 2 anni per effettuare 50 test!<br /> Procurarsi almeno un kit <em>Auris</em>ID significa sottoscrivere una polizza contro <em>Candida auris</em>.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1683104938589-10-1016894281727761689428277407"><span>Nel tuo centro esiste un collegamento efficace fra clinica e laboratorio?</span></a></p></div><div id="1683104938589-10-1016894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p>LionDx si rende disponibile ad organizzare incontri formativi presso la tua struttura in modo da rendere più efficace il collegamento fra il comparto clinico e quello diagnostico.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1685627490405-12-616894281727761689428277407"><span>Sono stati fatti studi sul Kit AurisID prodotto da OLM Diagnostics?</span></a></p></div><div id="1685627490405-12-616894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p><strong>Il “Journal of Fungi, ha pubblicato il paper “Validation and implementation of a commercial real-time PCR assay for direct detection of <em>Candida auris</em> from surveillance samples”.</strong></p><p><strong>Gli autori sono: </strong>Juan V. Mulet Bayona, Carme Salvador García, Nuria Tormo Palop, Concepción Gimeno Cardona</p><p>Di cui riportiamo le conclusioni:</p><p>Our PCR method using the <em>Auris</em>ID® kit allows a reduction in the turnaround time for surveillance of <em>C. auris </em>compared with other methods. These results are expected to contribute to control C. auris outbreaks, allowing isolation of patients and cleaning of environmental surfaces in advance.</p></div><span class="btn-container" ><a href="https://liondx.com/wp-content/uploads/2023/06/Sorveglianza-Candida-auris-RealTime-PCR.pdf" class="custom-link btn btn-sm border-width-0 btn-color-648163 btn-icon-left" title="Candida Auris, Candidosi invasiva, CE-IVD, Real-Time PCR" target="_blank">STUDIO</a></span></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1685628086730-13-716894281727761689428277407"><span>Come acquistare AurisID in trattativa diretta sul MEPA?</span></a></p></div><div id="1685628086730-13-716894281727761689428277407" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p><em>Auris</em>ID si può acquistare tramite trattativa diretta sul MEPA, presentando domanda all’ufficio amministrazione della propria struttura. Il kit, infatti, ha prestazioni uniche sul mercato ed è accompagnato da dichiarazione di unicità. LionDx è a tua disposizione per formulare la migliore offerta e sostenerti nel percorso di richiesta e di acquisto.</p></div></div></div></div><div class="panel panel-default wpb_accordion_section group"><div class="panel-heading wpb_accordion_header ui-accordion-header" role="tab"><p class="panel-title font-weight- text- icon-size-rg"><a data-toggle="collapse" data-parent="#accordion_1097126682" href="#1689428335299-14-2"><span>Sorveglianza Candida auris - Circolare del Ministero della Salute</span></a></p></div><div id="1689428335299-14-2" class="panel-collapse collapse" role="tabpanel"><div class="panel-body wpb_accordion_content ui-accordion-content half-internal-gutter single-block-padding"><div class="uncode_text_column" ><p>«Il numero di casi di infezione/colonizzazione da <em>Candida auris</em> continua ad aumentare rapidamente in molti paesi. […] In Italia, nel periodo 1° luglio 2019 – 22 dicembre 2022 sono stati notificati allo scrivente Ministero 361 casi di infezione/colonizzazione (età mediana circa 64 anni, range 0–91, soprattutto maschi) da 17 strutture sanitarie in quattro regioni (Liguria 82%, Piemonte 13%, Emilia-Romagna 4%, Veneto 1 caso), di cui almeno 146 (40%) deceduti. Oltre il 90% dei casi erano colonizzati, almeno la metà presentavano comorbidità e almeno un terzo era SARS-CoV-2 positivo. Nello stesso periodo, altri casi di infezione/colonizzazione (almeno 206 casi) non sono stati notificati. Successivamente, sono stati notificati altri casi (circa 40), con l’interessamento anche di due Regioni che non avevano notificato casi in precedenza (Liguria, Piemonte, Lazio, Toscana). Si rappresenta, pertanto, <strong>un crescente rischio di trasmissione intraospedaliera, di possibile sviluppo di candidemia soprattutto in caso di colonizzazione simultanea multipla, e di diffusione comunitaria.</strong></p><p>[…] Pertanto, è opportuno <strong>identificare e sottoporre a screening i soggetti che hanno condiviso la stanza con un paziente infetto/colonizzato anche se questi sono stati dimessi dalla struttura. </strong></p><p>[…]<strong> Nei reparti critici in cui si continuano a registrare</strong> <strong>casi, è importante considerare l’opportunità di screening per il personale sanitario che vi è impegnato, per es. tramite</strong> <strong>coltura dell’impronta della mano su piastra agarizzata, oltre alle procedure di sanificazione ambientale ordinaria e</strong> <strong>straordinaria. </strong></p><p><span style="color: #ff0000;">[…] È indicato lo screening per <em>C. auris </em>al momento del ricovero nei soggetti con storia di degenza ospedaliera (di almeno una notte) o attività di riabilitazione, nei precedenti 12 mesi, in strutture di assistenza situate nelle regioni maggiormente interessate.»</span></p></div></div></div></div></div></div></div></div></div></div></div><div class="wpb_column pos-top pos-left align_left column_parent col-lg-6 single-internal-gutter"><div class="uncol style-light animate_when_almost_visible bottom-t-top" data-delay="600"><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ></div></div></div></div></div><script id="script-row-unique-3" data-row="script-row-unique-3" type="text/javascript" class="vc_controls">UNCODE.initRow(document.getElementById("row-unique-3"));</script></div></div></div><div data-parent="true" class="vc_row row-container onepage-section" data-label="neonatale" data-name="neonatale" id="row-unique-4"><div class="row double-top-padding single-bottom-padding triple-h-padding full-width row-parent"><div class="wpb_row row-inner"><div class="wpb_column pos-top pos-left align_left column_parent col-lg-6 single-internal-gutter"><div class="uncol style-light animate_when_almost_visible bottom-t-top" data-delay="300"><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ><div class="vc_row row-internal row-container"><div class="row row-child"><div class="wpb_row row-inner"><div class="wpb_column pos-top pos-center align_left column_child col-lg-8 single-internal-gutter"><div class="uncol style-light" ><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ><span class="btn-container btn-block" ><a href="https://liondx.com/wp-content/uploads/2024/02/Kit-Candida-auris-CE-IVD-PCR-2024.pdf" class="custom-link btn btn-sm border-width-0 btn-color-648163 btn-block btn-no-scale btn-icon-left" title="Candida Auris, Candidosi invasiva, CE-IVD, Real-Time PCR" target="_blank">PIù INFORMAZIONI</a></span><span class="btn-container btn-block" ><a href="https://liondx.com/wp-content/uploads/2023/06/Sorveglianza-Candida-auris-RealTime-PCR.pdf" class="custom-link btn btn-sm border-width-0 btn-color-648163 btn-block btn-no-scale btn-icon-left" title="Candida Auris, Candidosi invasiva, CE-IVD, Real-Time PCR" target="_blank">STUDIO</a></span><span class="btn-container btn-block" ><a href="https://liondx.com/wp-content/uploads/2023/07/Sorveglianza-Candida-auris-Ministero-della-Salute.pdf" class="custom-link btn btn-sm border-width-0 btn-color-648163 btn-block btn-no-scale btn-icon-left" title="Candida Auris, Candidosi invasiva, CE-IVD, Real-Time PCR" target="_blank">CIRCOLARE DEL MINISTERO DELLA SALUTE</a></span></div></div></div></div></div><div class="wpb_column pos-top pos-center align_left column_child col-lg-4 single-internal-gutter"><div class="uncol style-light" ><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ></div></div></div></div></div></div></div></div></div></div></div></div></div><div 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border-width-0 text-default-color btn-no-scale btn-icon-left" title="Candida Auris, Candidosi invasiva, CE-IVD, Real-Time PCR"><i class="fa fa-arrow-left2"></i>TORNA A FUNGHI: REAL TIME PCR</a></span></div></div></div></div></div><div class="wpb_column pos-top pos-center align_left column_parent col-lg-6 single-internal-gutter"><div class="uncol style-light" ><div class="uncoltable"><div class="uncell no-block-padding" ><div class="uncont" ></div></div></div></div></div><script id="script-row-unique-5" data-row="script-row-unique-5" type="text/javascript" class="vc_controls">UNCODE.initRow(document.getElementById("row-unique-5"));</script></div></div></div><div class="row-container"><div class="row row-parent style-light no-top-padding double-bottom-padding" style="max-width: 1200px; margin: auto;"><div class="post-tag-share-container flex-center"><div class="post-share text-center"><div class="detail-container margin-auto"><div class="share-button share-buttons share-inline 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