Isolation and Antifungal Susceptibility Pattern of Candida albicans from Endocervical and High Vaginal Swabs of Pregnant Women Attending State Specialist Hospital Gombe, Nigeria

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Susceptibility Pattern of Candida albicans from Endocervical and High Vaginal Swabs of Pregnant Women Attending State Specialist Hospital Gombe, Nigeria</title> <meta name="description" content="Isolation and Antifungal Susceptibility Pattern of Candida albicans from Endocervical and High Vaginal Swabs of Pregnant Women Attending State Specialist Hospital Gombe, Nigeria"> <meta name="keywords" content="Candida albicans, candidiasis, endocervical, vaginal swab, antifungal susceptibility, imidazole, triazoles "> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link 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A. Mu鈥檌nat</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20U.%20Maigari"> F. U. Maigari</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20A.%20Mani"> M. A. Mani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Candida albicans is the common cause of both oral and vaginal candidiasis in humans. This candidiasis leads to a wide range of physical, psychological and even physiological problems in humans particularly pregnant women. Samples of endocervical and high vaginal swab were collected from 200 women attending Gombe Specialist Hospital and inoculated on Saboraud Dextrose Agar (SDA) incorporated with chloramphenicol to get rid of the unwanted bacterial contaminants. Gram staining technique and germ tube test were employed for the identification, as Candida albicans is positive for both. Gram positive samples were 70% (n=140) and were further subjected to germ tube test. The remaining 30% (n=60) were found to be Gram negative. 90% (n=126) of the Gram positive ones isolated were also found to be positive for germ tube test; confirming the presence of Candida albicans. Antifungal susceptibility testing revealed that members of Imidazole (Ketoconazole, Miconazole) and those of Triazoles (Fluconazole and Itraconazole) were found to be more effective at concentrations of 20, 50 and 100 碌g/disc compared to Griseofulvin (Fulcin) with only 26.00 mm zone of inhibition at 100 碌g/disc concentration. <iframe src="https://publications.waset.org/abstracts/13954.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Candida%20albicans" title="Candida albicans">Candida albicans</a>, <a href="https://publications.waset.org/abstracts/search?q=candidiasis" title=" candidiasis"> candidiasis</a>, <a href="https://publications.waset.org/abstracts/search?q=endocervical" title=" endocervical"> endocervical</a>, <a href="https://publications.waset.org/abstracts/search?q=vaginal%20swab" title=" vaginal swab"> vaginal swab</a>, <a href="https://publications.waset.org/abstracts/search?q=antifungal%20susceptibility" title=" antifungal susceptibility"> antifungal susceptibility</a>, <a href="https://publications.waset.org/abstracts/search?q=imidazole" title=" imidazole"> imidazole</a>, <a href="https://publications.waset.org/abstracts/search?q=triazoles" title=" triazoles "> triazoles </a> </p> <a href="https://publications.waset.org/abstracts/13954/isolation-and-antifungal-susceptibility-pattern-of-candida-albicans-from-endocervical-and-high-vaginal-swabs-of-pregnant-women-attending-state-specialist-hospital-gombe-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13954.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">332</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div 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Isolation and Antifungal Susceptibility Pattern of Candida albicans from Endocervical and High Vaginal Swabs of Pregnant Women Attending State Specialist Hospital Gombe, Nigeria