CINXE.COM

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Krebs - Facts" data-related="1" > Edwin G. Krebs - Facts </a> </li> </ol> </noscript> <div id="pjax-well" class="container page-content-area"> <div class="pjax-container" > <section class="page-section laureate-facts laur-447"> <aside class="page-aside border-top"> <header class="header"> <h5 class="heading"> <a href="https://www.nobelprize.org/prizes/medicine/1992/summary/"> The Nobel Prize in Physiology or Medicine 1992 </a> </h5> </header> <nav class="aside-navigation aside-navigation--desktop" aria-label="In Page Navigation"> <ul class="aside-navigation__list"><li class="aside-navigation__list-item"> <a href="https://www.nobelprize.org/prizes/medicine/1992/summary/" aria-current="false" > Summary </a> </li><li class="aside-navigation__list-item">Laureates<ul class="aside-navigation__list"><li class="aside-navigation__list-item"> <a href="https://www.nobelprize.org/prizes/medicine/1992/fischer/facts/" aria-current="false" > Edmond H. Fischer </a> </li><li class="aside-navigation__list-item">Edwin G. 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Krebs </h1> <h2>Facts</h2> </header> <select class="aside-navigation aside-navigation--mobile js-aside-navigation--mobile" name="Go to laureate page"> <option value="" selected disabled>Navigate to:</option> <option value="https://www.nobelprize.org/prizes/medicine/1992/summary/"> Summary</option><optgroup label=" Laureates"><option value="https://www.nobelprize.org/prizes/medicine/1992/fischer/facts/">- Edmond H. Fischer</option><optgroup label="- Edwin G. Krebs"><option value="https://www.nobelprize.org/prizes/medicine/1992/krebs/facts/" disabled selected>-- Facts</option><option value="https://www.nobelprize.org/prizes/medicine/1992/krebs/biographical/">-- Biographical</option><option value="https://www.nobelprize.org/prizes/medicine/1992/krebs/lecture/">-- Nobel Lecture</option><option value="https://www.nobelprize.org/prizes/medicine/1992/krebs/other-resources/">-- Other resources</option></optgroup></optgroup><option value="https://www.nobelprize.org/prizes/medicine/1992/press-release/"> Press release</option><option value="https://www.nobelprize.org/prizes/medicine/1992/illustrated-information/"> Illustrated information</option><option value="https://www.nobelprize.org/prizes/medicine/1992/ceremony-speech/"> Award ceremony speech</option></select> <div class="image"> <picture ><source data-srcset="https://www.nobelprize.org/images/krebs-13441-portrait-mini-2x.jpg" media="(min-width: 220px)" /><source data-srcset="https://www.nobelprize.org/images/krebs-13441-portrait-small-2x.jpg" media="(min-width: 900px)" /><source data-srcset="https://www.nobelprize.org/images/krebs-13441-portrait-medium-2x.jpg" media="(min-width: 1400px)" /><img class="lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" alt="Edwin G. Krebs" /><noscript><img src="https://www.nobelprize.org/images/krebs-13441-portrait-medium.jpg" alt="Edwin G. Krebs" /></noscript></picture><figcaption class="figcaption"><p class="figcaption__attribution">Photo from the Nobel Foundation archive.</p></figcaption> </div> <div class="content"> <p> Edwin G. Krebs<br> The Nobel Prize in Physiology or Medicine 1992 </p> <p class="born-date">Born: 6 June 1918, Lansing, IA, USA </p> <p class="dead-date">Died: 21 December 2009, Seattle, WA, USA </p> <p> Affiliation at the time of the award: University of Washington, Seattle, WA, USA </p> <p> Prize motivation: “for their discoveries concerning reversible protein phosphorylation as a biological regulatory mechanism” </p> <p> Prize share: 1/2 </p> </div> <div class="description border-top"> <h3> Work </h3> <p> <p>The element phosphorus and phosphate groups, consisting of phosphorous and oxygen atoms, play an important role in several vital biochemical processes. In the mid-1950s Edwin Krebs and Edmond Fischer were able to describe how processes in which proteins emit and absorb phosphate groups can take place in both directions. They demonstrated how the process is governed by special enzymes—proteins that speed up the transformation of other proteins without being incorporated in the final products of the process. These processes are important in the regulation of metabolism in the body and other functions.</p> </p> </div> <footer class="border-top pagecite" itemscope itemtype="http://schema.org/citation"> <p> To cite this section <br> MLA style: Edwin G. Krebs – Facts. NobelPrize.org. Nobel Prize Outreach AB 2024. 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