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Pre-Conference Workshop - 3rd Targeted Radiopharmaceuticals Summit US 2024
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fl-node-t96q3n8fzoje" data-node="t96q3n8fzoje"> <div class="fl-col fl-node-bhi6p8jeudvw fl-col-bg-color fl-col-small" data-node="bhi6p8jeudvw"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-icon fl-node-ju7lygv2n9zp" data-node="ju7lygv2n9zp"> <div class="fl-module-content fl-node-content"> <div class="fl-icon-wrap"> <span class="fl-icon"> <a href="https://targeted-radiopharma-us.com/whats-on/speakers/" target="_self"> <i class="fas fa-angle-double-left" aria-hidden="true"></i> </a> </span> </div> </div> </div> </div> </div> <div class="fl-col fl-node-ci6r5gpsdnv1 fl-col-bg-color" data-node="ci6r5gpsdnv1"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-heading fl-node-toe4crmgl6p8" data-node="toe4crmgl6p8"> <div class="fl-module-content fl-node-content"> <h2 class="fl-heading"> <span class="fl-heading-text"><b>Pre-Conference Workshop Day</b><br>Tuesday, July 30 2024</span> </h2> </div> </div> </div> </div> <div class="fl-col fl-node-20ivd49qmg58 fl-col-bg-color fl-col-small" data-node="20ivd49qmg58"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-icon fl-node-3k9swfbe67cg" data-node="3k9swfbe67cg"> <div class="fl-module-content fl-node-content"> <div class="fl-icon-wrap"> <span class="fl-icon"> <a href="https://targeted-radiopharma-us.com/whats-on/agenda/day-one/" target="_self"> <i class="fas fa-angle-double-right" aria-hidden="true"></i> </a> </span> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="fl-row fl-row-fixed-width fl-row-bg-none fl-node-8xpvuntficz3 fl-row-default-height fl-row-align-center" data-node="8xpvuntficz3"> <div class="fl-row-content-wrap"> <div class="fl-row-content fl-row-fixed-width fl-node-content"> <div class="fl-col-group fl-node-vimc02hen8sq" data-node="vimc02hen8sq"> <div class="fl-col fl-node-zd6ct0xw14ev fl-col-bg-color" data-node="zd6ct0xw14ev"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-8k7dfoi5aen4" data-node="8k7dfoi5aen4"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #ebf6fc"> <h3> <span class="time"> 7:30 am </span> <center><span style="color: #67A5CB;">Check-in & Light Breakfast</span></center> </h3> <!-- Speaker List --> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> </div> <!-- /Agenda content --> </div> <div class="inner-agenda" style="background: #f0f0f0"> <h3> <span class="time"> </span> </h3> <style id='fl-builder-layout-22669-inline-css'> .fl-node-h9aztwvbkp1j {width: 50%;}.fl-node-nxbcotuhrj05 {width: 50%;}.inner-agenda {background: #f0f0f0;margin-bottom: 20px;padding: 20px;}.inner-agenda:last-child {margin-bottom: 0px;}.inner-agenda span.time {color: #082883 ;}.inner-agenda h3 {color: #000;font-size: 16px;}h3.eehw-agenda-synopsis {color: #082883 ;padding-top: 20px;}h1.eehw-agenda-title {background: #082883 ;color: #fff;font-weight: bold;margin-bottom: 20px;margin-top: 0px;padding: 20px;}h1.eehw-agenda-title p {margin: 0;font-size: 18px;font-weight: bold;margin-top: 5px;}.fl-module-ee-agenda ul.non-expand-speaker-list {padding-left: 0px;}.fl-module-ee-agenda ul.non-expand-speaker-list li {list-style: none;text-indent: 0px;}.eehw-speaker {margin-top: 30px;}.eehw-speakers-thumb {float: left;margin-right: 20px;}.inner-agenda-workshop p ul li {list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 100%;}.inner-agenda-workshop h2 {font-size: 22px;}a.view-speaker {display: block;}.fl-module-ee-agenda .fl-builder-layout-template .fl-row-content-wrap {margin: 0;padding: 0;background: #f0f0f0;margin-bottom: 20px;}@media screen and (max-width: 768px) {}.inner-agenda {background: #f0f0f0;margin-bottom: 20px;padding: 20px;}.inner-agenda:last-child {margin-bottom: 0px;}.inner-agenda span.time {color: #082883 ;}.inner-agenda h3 {color: #000;font-size: 16px;}h3.eehw-agenda-synopsis {color: #082883 ;padding-top: 20px;}h1.eehw-agenda-title {background: #082883 ;color: #fff;font-weight: bold;margin-bottom: 20px;margin-top: 0px;padding: 20px;}h1.eehw-agenda-title p {margin: 0;font-size: 18px;font-weight: bold;margin-top: 5px;}.fl-module-ee-agenda ul.non-expand-speaker-list {padding-left: 0px;}.fl-module-ee-agenda ul.non-expand-speaker-list li {list-style: none;text-indent: 0px;}.eehw-speaker {margin-top: 30px;}.eehw-speakers-thumb {float: left;margin-right: 20px;}.inner-agenda-workshop p ul li {list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 100%;}.inner-agenda-workshop h2 {font-size: 22px;}a.view-speaker {display: block;}.fl-module-ee-agenda .fl-builder-layout-template .fl-row-content-wrap {margin: 0;padding: 0;background: #f0f0f0;margin-bottom: 20px;}@media screen and (max-width: 768px) {} </style> <div class="fl-builder-content fl-builder-content-22669 fl-builder-template fl-builder-layout-template fl-builder-global-templates-locked" data-post-id="22669"><div class="fl-row fl-row-fixed-width fl-row-bg-none fl-node-smn2kp4zqfw9 fl-row-default-height fl-row-align-center" data-node="smn2kp4zqfw9"> <div class="fl-row-content-wrap"> <div class="fl-row-content fl-row-fixed-width fl-node-content"> <div class="fl-col-group fl-node-p9ygoh6tz1f3" data-node="p9ygoh6tz1f3"> <div class="fl-col fl-node-h9aztwvbkp1j fl-col-bg-color fl-col-small" data-node="h9aztwvbkp1j"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-xvhazrl9ku5b" data-node="xvhazrl9ku5b"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #666665"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop A</span></center> </h3> <!-- Speaker List --> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> </div> <!-- /Agenda content --> </div> <div class="inner-agenda" style="background: #f1f1f1"> <h3> <span class="time"> 8:30 am </span> Evaluating Novel Radiopharmaceutical Targeting Agents for Enhanced Specificity & Efficacy </h3> <!-- Speaker List --> <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22650" class="view-speaker" speaker-id="22650"><span>Jack Hoppin</span></a></em> Chief Executive Officer, Ratio Therapeutics </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22649" class="view-speaker" speaker-id="22649"><span>Simon Read</span></a></em> Founder & Chief Executive Officer, Mariana Oncology </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker23475" class="view-speaker" speaker-id="23475"><span>Zdravka Medarova</span></a></em> Chief Scientific Officer & Co-Founder, TransCode Therapeutics Inc. </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker23607" class="view-speaker" speaker-id="23607"><span>Sujiet Puthenveetil</span></a></em> Director, AstraZeneca </li> </ul> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>As we see more innovation to improve targeting approaches across radio conjugates, the design and development of these molecules is no easy ride. With the aim to balance the <strong>specificity</strong>, <strong>efficacy</strong> and <strong>radiation exposure</strong> to <strong>non-targeted tissues</strong>, this workshop will critically analyze current targeting approaches.</p> <p></p> <p>Hear the latest content and dive into discussions on:</p> <p>• Delving into pharmacokinetic profiles to understand the parameters that dictates a successful radiopharmaceutical</p> <p>• Uncovering novel<strong> bispecific antibodies </strong>to target tissues</p> <p>• Exploring <strong>small molecules</strong>: substrate analogues and metabolic tracers for targeting</p> <p>• Evaluating novel <strong>peptide ligands</strong></p> <p>• Considerations for use in varying beta and alpha emitting isotopes</p> <p>• Comparing different approaches</p> <p>• Regulatory challenges for new modalities</p> </div> <!-- /Agenda content --> </div> </div> </div> </div> </div> </div> <div class="fl-col fl-node-nxbcotuhrj05 fl-col-bg-color fl-col-small" data-node="nxbcotuhrj05"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-wfe75h84xbap" data-node="wfe75h84xbap"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #73328e"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop D</span></center> </h3> <!-- Speaker List --> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> </div> <!-- /Agenda content --> </div> <div class="inner-agenda" style="background: #f1ebf4"> <h3> <span class="time"> 8:30 am </span> Addressing the Silos to Move Toward an Integrated Approach With Enhanced Trial Design & Execution Across Radiopharmaceutical Research </h3> <!-- Speaker List --> <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22661" class="view-speaker" speaker-id="22661"><span>Mary Jessel</span></a></em> Senior Vice President - Global Medical Affairs, Telix Pharmaceuticals </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22660" class="view-speaker" speaker-id="22660"><span>Scott Tagawa</span></a></em> Professor, Weill Cornell University </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22772" class="view-speaker" speaker-id="22772"><span>Matthew Korn</span></a></em> Global Medical Lead, Bayer </li> </ul> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>Radiopharmaceutical development is driven by collaboration between <strong>radio pharmacists</strong>, <strong>nuclear medicine specialists</strong>, <strong>chemists</strong>, <strong>bioengineers </strong>and more. While the industry is on the brink of expanding their horizons to even more unmet medical needs, there is a clear bottleneck in the blend of expertise required to design and run a radiopharmaceutical trial.</p> <p></p> <p>Learn perspectives from key clinicians and industry players to learn exactly how the field can operationalize clinical research:</p> <ul> <li>Identify the bottlenecks to uncover areas to be streamlined</li> <li>Explore specialized training solutions</li> <li>Integrating the sponsor and the clinicians toward a unified end goal</li> <li>Maintaining a <strong>patient-centric </strong>approach in trial design</li> <li>Enhancing <strong>integration of nuclear medicine</strong> in the clinic</li> <li>Understanding new challenges specific to <strong>alpha emitters</strong></li> </ul> </div> <!-- /Agenda content --> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="inner-agenda" style="background: #ebf6fc"> <h3> <span class="time"> 10:30 am </span> <center><span style="color: #67A5CB;">Morning Break & Networking</span></center> </h3> <!-- Speaker List --> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> </div> <!-- /Agenda content --> </div> <div class="inner-agenda" style="background: #f0f0f0"> <h3> <span class="time"> </span> </h3> <style id='fl-builder-layout-22699-inline-css'> .fl-node-w5kfb2m7xavl {width: 50%;}.fl-node-v0mgbshur8aq {width: 50%;}.inner-agenda {background: #f0f0f0;margin-bottom: 20px;padding: 20px;}.inner-agenda:last-child {margin-bottom: 0px;}.inner-agenda span.time {color: #082883 ;}.inner-agenda h3 {color: #000;font-size: 16px;}h3.eehw-agenda-synopsis {color: #082883 ;padding-top: 20px;}h1.eehw-agenda-title {background: #082883 ;color: #fff;font-weight: bold;margin-bottom: 20px;margin-top: 0px;padding: 20px;}h1.eehw-agenda-title p {margin: 0;font-size: 18px;font-weight: bold;margin-top: 5px;}.fl-module-ee-agenda ul.non-expand-speaker-list {padding-left: 0px;}.fl-module-ee-agenda ul.non-expand-speaker-list li {list-style: none;text-indent: 0px;}.eehw-speaker {margin-top: 30px;}.eehw-speakers-thumb {float: left;margin-right: 20px;}.inner-agenda-workshop p ul li {list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 100%;}.inner-agenda-workshop h2 {font-size: 22px;}a.view-speaker {display: block;}.fl-module-ee-agenda .fl-builder-layout-template .fl-row-content-wrap {margin: 0;padding: 0;background: #f0f0f0;margin-bottom: 20px;}@media screen and (max-width: 768px) {}.inner-agenda {background: #f0f0f0;margin-bottom: 20px;padding: 20px;}.inner-agenda:last-child {margin-bottom: 0px;}.inner-agenda span.time {color: #082883 ;}.inner-agenda h3 {color: #000;font-size: 16px;}h3.eehw-agenda-synopsis {color: #082883 ;padding-top: 20px;}h1.eehw-agenda-title {background: #082883 ;color: #fff;font-weight: bold;margin-bottom: 20px;margin-top: 0px;padding: 20px;}h1.eehw-agenda-title p {margin: 0;font-size: 18px;font-weight: bold;margin-top: 5px;}.fl-module-ee-agenda ul.non-expand-speaker-list {padding-left: 0px;}.fl-module-ee-agenda ul.non-expand-speaker-list li {list-style: none;text-indent: 0px;}.eehw-speaker {margin-top: 30px;}.eehw-speakers-thumb {float: left;margin-right: 20px;}.inner-agenda-workshop p ul li {list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 100%;}.inner-agenda-workshop h2 {font-size: 22px;}a.view-speaker {display: block;}.fl-module-ee-agenda .fl-builder-layout-template .fl-row-content-wrap {margin: 0;padding: 0;background: #f0f0f0;margin-bottom: 20px;}@media screen and (max-width: 768px) {} </style> <div class="fl-builder-content fl-builder-content-22699 fl-builder-template fl-builder-layout-template fl-builder-global-templates-locked" data-post-id="22699"><div class="fl-row fl-row-fixed-width fl-row-bg-none fl-node-1c3qfgk8odb9 fl-row-default-height fl-row-align-center" data-node="1c3qfgk8odb9"> <div class="fl-row-content-wrap"> <div class="fl-row-content fl-row-fixed-width fl-node-content"> <div class="fl-col-group fl-node-acy4r57o2ki0" data-node="acy4r57o2ki0"> <div class="fl-col fl-node-w5kfb2m7xavl fl-col-bg-color fl-col-small" data-node="w5kfb2m7xavl"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-g5ov7is31402" data-node="g5ov7is31402"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #666665"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop B</span></center> </h3> <!-- Speaker List --> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> </div> <!-- /Agenda content --> </div> <div class="inner-agenda" style="background: #ededed"> <h3> <span class="time"> 11:00 am </span> Maximizing Combination Approaches to Transform Safety & Efficacy Profiles </h3> <!-- Speaker List --> <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22692" class="view-speaker" speaker-id="22692"><span>Zachary Morris</span></a></em> Associate Professor and Vice-Chair, University of Wisconsin-Madison </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22660" class="view-speaker" speaker-id="22660"><span>Scott Tagawa</span></a></em> Professor, Weill Cornell University </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22712" class="view-speaker" speaker-id="22712"><span>Volker Wagner</span></a></em> Chief Medical Officer, OranoMed </li> </ul> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>Garnering excitement across the precision oncology field, combination-based approaches have proven to expand therapeutic efficacy and optimize treatment outcomes. It is no surprise that the radiopharmaceuticals space is following full steam ahead, as we see early clinical data and uncover more about the preclinical learnings in dual therapies.</p> <p></p> <p>Discover more on combinations:</p> <p>• Explore<strong> immune checkpoint modulators</strong> with radioligands</p> <p>• Utilize DNA repair inhibitors such as <strong>PARP</strong>, <strong>ATM/ATR</strong> and <strong>DNA methyltransferases</strong></p> <p>• Uncovering immune profiles stimulated by alpha and beta emission</p> <p>• Understand challenges with increased complexity of treatment regimens</p> </div> <!-- /Agenda content --> </div> </div> </div> </div> </div> </div> <div class="fl-col fl-node-v0mgbshur8aq fl-col-bg-color fl-col-small" data-node="v0mgbshur8aq"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-wgka2todp3x1" data-node="wgka2todp3x1"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #73328e"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop E</span></center> </h3> <!-- Speaker List --> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> </div> <!-- /Agenda content --> </div> <div class="inner-agenda" style="background: #f1ebf4"> <h3> <span class="time"> 11:00 am </span> Advancing Dosimetry Data: An Invaluable Tool to Optimize Therapeutic Outcomes </h3> <!-- Speaker List --> <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22650" class="view-speaker" speaker-id="22650"><span>Jack Hoppin</span></a></em> Chief Executive Officer, Ratio Therapeutics </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22684" class="view-speaker" speaker-id="22684"><span>Nadine Mallak</span></a></em> Associate & Assistant Professor, OHSU - Oregon Health & Science University </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22686" class="view-speaker" speaker-id="22686"><span>Shankar Vallabhajosula</span></a></em> Vice President, Radiopharmaceutical Sciences, Convergent Therapeutics </li> </ul> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>Dosimetry data gives precise insight into radiation <strong>dose delivery</strong> and <strong>tissue penetration</strong>, but there is still work to be done to unlock the true potential of this tool. From understanding dose-response relationships and establishing safe dose limits for normal organs to overcoming logistical hurdles in <strong>clinical implementation</strong>. There is ongoing research and development efforts to improve <strong>dosimetry models</strong>, enhance imaging techniques, and gather more data on radiopharmaceutical pharmacokinetics and biodistribution – but how can this truly be implemented in the clinic?</p> <p></p> <p>Partake in this workshop to accelerate the field of dosimetry and hear insights on:</p> <ul> <li>Revealing current regulatory perspectives and guidelines and identifying the need for future clarification</li> <li>Reaching new definitions to overcome <strong>external beam</strong> challenges</li> <li>Uncovering new <strong>analytical tools</strong></li> <li>Addressing <strong>differences in the image analysis</strong></li> <li>Machine learning and AI to enhance dosimetry insights</li> <li><strong>Alpha vs</strong>.<strong> beta dosimetry</strong> of therapeutic radiopharmaceuticals</li> <li>Relative biological effect (RBE) and alpha dosimetry</li> <li>Role of alpha dosimetry in the design of clinical trials</li> </ul> </div> <!-- /Agenda content --> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="inner-agenda" style="background: #ebf6fc"> <h3> <span class="time"> 1:00 pm </span> <center><span style="color: #67A5CB;"> Lunch Break & Networking</span></center> </h3> <!-- Speaker List --> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> </div> <!-- /Agenda content --> </div> <div class="inner-agenda" style="background: #f0f0f0"> <h3> <span class="time"> </span> </h3> <style id='fl-builder-layout-22734-inline-css'> .fl-node-7gs9zwmpkhtf {width: 50%;}.fl-node-znjt68hkm7xp {width: 50%;}.inner-agenda {background: #f0f0f0;margin-bottom: 20px;padding: 20px;}.inner-agenda:last-child {margin-bottom: 0px;}.inner-agenda span.time {color: #082883 ;}.inner-agenda h3 {color: #000;font-size: 16px;}h3.eehw-agenda-synopsis {color: #082883 ;padding-top: 20px;}h1.eehw-agenda-title {background: #082883 ;color: 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;padding-top: 20px;}h1.eehw-agenda-title {background: #082883 ;color: #fff;font-weight: bold;margin-bottom: 20px;margin-top: 0px;padding: 20px;}h1.eehw-agenda-title p {margin: 0;font-size: 18px;font-weight: bold;margin-top: 5px;}.fl-module-ee-agenda ul.non-expand-speaker-list {padding-left: 0px;}.fl-module-ee-agenda ul.non-expand-speaker-list li {list-style: none;text-indent: 0px;}.eehw-speaker {margin-top: 30px;}.eehw-speakers-thumb {float: left;margin-right: 20px;}.inner-agenda-workshop p ul li {list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 100%;}.inner-agenda-workshop h2 {font-size: 22px;}a.view-speaker {display: block;}.fl-module-ee-agenda .fl-builder-layout-template .fl-row-content-wrap {margin: 0;padding: 0;background: #f0f0f0;margin-bottom: 20px;}@media screen and (max-width: 768px) {} </style> <div class="fl-builder-content fl-builder-content-22734 fl-builder-template fl-builder-layout-template fl-builder-global-templates-locked" data-post-id="22734"><div class="fl-row fl-row-fixed-width fl-row-bg-none fl-node-kp5rjtyhvmdn fl-row-default-height fl-row-align-center" data-node="kp5rjtyhvmdn"> <div class="fl-row-content-wrap"> <div class="fl-row-content fl-row-fixed-width fl-node-content"> <div class="fl-col-group fl-node-4qv65b3orzp2" data-node="4qv65b3orzp2"> <div class="fl-col fl-node-7gs9zwmpkhtf fl-col-bg-color fl-col-small" data-node="7gs9zwmpkhtf"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-ym029pzcslw1" data-node="ym029pzcslw1"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #666665"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop C</span></center> </h3> <!-- Speaker List --> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> </div> <!-- /Agenda content --> </div> <div class="inner-agenda" style="background: #ededed"> <h3> <span class="time"> 2:00 pm </span> Refining Your Drug Candidates Through Pre-Clinical Lead Optimization to Ensure Translational Success – Dive into the Discussions </h3> <!-- Speaker List --> <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22649" class="view-speaker" speaker-id="22649"><span>Simon Read</span></a></em> Founder & Chief Executive Officer, Mariana Oncology </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22711" class="view-speaker" speaker-id="22711"><span>Anna Karmann</span></a></em> Chief Medical Officer, AdvanCell </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22715" class="view-speaker" speaker-id="22715"><span>Nicholas Pullen</span></a></em> CSO, ARTBIO </li> </ul> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>Refining potential drug targets before they advance to costly and time-intensive clinical trials is important. With more organizations working across novel targeting agents, further radioisotopes,<strong> new linkers </strong>and <strong>chelators </strong>– lead optimization is integral for translational success leading to the development of safer and more effective drugs for patients.</p> <p></p> <p>Join this interactive workshop to hear more on:</p> <ul> <li>Uncovering <strong>preclinical evaluation </strong>processes to select efficiently good radiolabeled molecules</li> <li>Assessing the addition of<strong> linkers</strong> and choice of <strong>chelating</strong> agent</li> <li>Screening combinations of <strong>radiometal complexes</strong>, linker and <strong>conjugation</strong> function</li> <li>Novel platforms to design new molecules</li> <li>Enhancing PKPD, binding affinity and biodistribution</li> <li>Assessing and mitigating your translational risk</li> </ul> </div> <!-- /Agenda content --> </div> </div> </div> </div> </div> </div> <div class="fl-col fl-node-znjt68hkm7xp fl-col-bg-color fl-col-small" data-node="znjt68hkm7xp"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-adoh0ki6b8c5" data-node="adoh0ki6b8c5"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #73328e"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop F</span></center> </h3> <!-- Speaker List --> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> </div> <!-- /Agenda content --> </div> <div class="inner-agenda" style="background: #f1ebf4"> <h3> <span class="time"> 2:00 pm </span> A Personalized Future: Tailoring the Optimal Patient Care </h3> <!-- Speaker List --> <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22722" class="view-speaker" speaker-id="22722"><span>Elcin Zan</span></a></em> Assistant Professor, Cleveland Clinic </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22726" class="view-speaker" speaker-id="22726"><span>Amir Iravani</span></a></em> Associate Professor, University of Washington- Fred Hutchinson Cancer Center, Seattle, WA </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker22728" class="view-speaker" speaker-id="22728"><span>Andrew Thompson</span></a></em> Radiation Oncologist, Beaumont Health System </li> <li> <em><a href="https://targeted-radiopharma-us.com/speakers/#speaker23436" class="view-speaker" speaker-id="23436"><span>Darshan Dalal</span></a></em> Global Product Leader, AstraZeneca </li> </ul> <!-- /Speaker List --> <div class="clearfix"></div> <!-- Agenda content --> <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>Explore the potential of personalized approach in radiopharmaceutical therapies and the obstacles to its broader adoption. With the unique opportunity to take advantage of dosimetry data, the industry is exploring how the next TRPs can be individually adapted.</p> <p></p> <p>Explore future perspectives for tailored treatments by joining this workshop:</p> <ul> <li>Use dosimetry to guide personalized treatment and dosing approaches</li> <li>Leverage <strong>artificial intelligence</strong> and machine learning to further enhance radiopharmaceuticals’ potential for predictive modelling, image analysis, and treatment optimization</li> <li>Advance personalization with <strong>combination treatments</strong></li> <li>Gain <strong>regulatory perspectives</strong></li> </ul> </div> <!-- /Agenda content --> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="inner-agenda" style="background: #ebf6fc"> <h3> <span class="time"> 4:00 pm </span> <center><span style="color: #67A5CB;">End of Pre-Conference Day</span></center> </h3> <!-- Speaker List --> <!-- /Speaker List --> 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Limited is registered in England & Wales, number 06752216.<br />Registered Office: Eastcastle House, 27/28 Eastcastle Street, London, W1W 8DH.</small></p> </div> </div> </div> </div> </div> </div> </div> </div> </div> </footer> </div><!-- .fl-page --> <script type="text/javascript"> // EE Custom Code document.addEventListener('DOMContentLoaded', function() { var url = new URL(window.location.href); // Get current URL var search_params = new URLSearchParams(url.search); // Get URL params // Function to remove the hash from the URL function removeHash() { if (url.hash) { var cleanUrl = window.location.origin + window.location.pathname + window.location.search; history.replaceState(null, null, cleanUrl); url = new URL(cleanUrl); // Update the URL object to the clean URL } } // Remove the hash immediately on page load removeHash(); // Check if UTM params exist if (search_params.has('utm_source') || search_params.has('utm_medium') || search_params.has('utm_campaign') || 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FLBuilderMenu({id:'5cb735f42d5d2',type:'horizontal',mobile:'text',mobileBelowRow:true,mobileFlyout:false,breakPoints:{large:1200,medium:992,small:768},mobileBreakpoint:'medium-mobile',postId:'54',mobileStacked:true,});});})(jQuery);;jQuery(function($){$(function(){$('.fl-node-fbin57uzaw2o .fl-photo-img').on('mouseenter',function(e){$(this).data('title',$(this).attr('title')).removeAttr('title');}).on('mouseleave',function(e){$(this).attr('title',$(this).data('title')).data('title',null);});});window._fl_string_to_slug_regex='a-zA-Z0-9';});;jQuery(function($){$(function(){$('.fl-node-xdh0wrma6eil .fl-photo-img').on('mouseenter',function(e){$(this).data('title',$(this).attr('title')).removeAttr('title');}).on('mouseleave',function(e){$(this).attr('title',$(this).data('title')).data('title',null);});});window._fl_string_to_slug_regex='a-zA-Z0-9';});;jQuery(function($){$(function(){$('.fl-node-htnd6kv9pmwj 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header=$('.fl-builder-content[data-type=header]'),windowSize=this.win.width(),makeSticky=false;makeSticky=this._makeWindowSticky(windowSize);if(makeSticky||(this.breakpointWidth>0&&windowSize>=this.breakpointWidth)){this.win.on('scroll.fl-theme-builder-header-sticky',$.proxy(this._doSticky,this));if(e&&'resize'===e.type){if(this.header.hasClass('fl-theme-builder-header-sticky')){this._doSticky(e);} this._adjustStickyHeaderWidth();} if(Number(header.attr('data-shrink'))){this.header.data('original-height',this.header.outerHeight());this.win.on('resize',$.throttle(500,$.proxy(this._initShrink,this)));this._initShrink();} this._initFlyoutMenuFix(e);}else{this.win.off('scroll.fl-theme-builder-header-sticky');this.win.off('resize.fl-theme-builder-header-sticky');this.header.removeClass('fl-theme-builder-header-sticky');this.header.removeAttr('style');this.header.parent().css('padding-top','0');}},_makeWindowSticky:function(windowSize){var makeSticky=false;switch(this.stickyOn){case'xl':makeSticky=windowSize>FLBuilderLayoutConfig.breakpoints['large'];break;case'':case'desktop':makeSticky=windowSize>=FLBuilderLayoutConfig.breakpoints['medium'];break;case'desktop-medium':makeSticky=windowSize>FLBuilderLayoutConfig.breakpoints['small'];break;case'large':makeSticky=windowSize>FLBuilderLayoutConfig.breakpoints['medium']&&windowSize<=FLBuilderLayoutConfig.breakpoints['large'];break;case'large-medium':makeSticky=windowSize>FLBuilderLayoutConfig.breakpoints['small']&&windowSize<=FLBuilderLayoutConfig.breakpoints['large'];break;case'medium':makeSticky=(windowSize<=FLBuilderLayoutConfig.breakpoints['medium']&&windowSize>FLBuilderLayoutConfig.breakpoints['small']);break;case'medium-mobile':makeSticky=(windowSize<=FLBuilderLayoutConfig.breakpoints['medium']);break;case'mobile':makeSticky=(windowSize<=FLBuilderLayoutConfig.breakpoints['small']);break;case'all':makeSticky=true;break;} return makeSticky;},_doSticky:function(e){var winTop=Math.floor(this.win.scrollTop()),headerTop=Math.floor(this.header.data('original-top')),hasStickyClass=this.header.hasClass('fl-theme-builder-header-sticky'),hasScrolledClass=this.header.hasClass('fl-theme-builder-header-scrolled'),beforeHeader=this.header.prevAll('.fl-builder-content'),bodyTopPadding=parseInt(jQuery('body').css('padding-top')),winBarHeight=$('#wpadminbar').length?$('#wpadminbar').outerHeight():0,headerHeight=0;if(isNaN(bodyTopPadding)){bodyTopPadding=0;} if(this.hasAdminBar&&this.win.width()>600){winTop+=Math.floor(winBarHeight);} if(winTop>headerTop){if(!hasStickyClass){if(e&&('scroll'===e.type||'smartscroll'===e.type)){this.header.addClass('fl-theme-builder-header-sticky');if(this.overlay&&beforeHeader.length){this.header.css('top',winBarHeight);}} if(!this.overlay){this._adjustHeaderHeight();}}} else if(hasStickyClass){this.header.removeClass('fl-theme-builder-header-sticky');this.header.removeAttr('style');this.header.parent().css('padding-top','0');} this._adjustStickyHeaderWidth();if(winTop>headerTop){if(!hasScrolledClass){this.header.addClass('fl-theme-builder-header-scrolled');}}else if(hasScrolledClass){this.header.removeClass('fl-theme-builder-header-scrolled');} this._flyoutMenuFix(e);},_initFlyoutMenuFix:function(e){var header=this.header,menuModule=header.closest('.fl-menu'),flyoutMenu=menuModule.find('.fl-menu-mobile-flyout'),isPushMenu=menuModule.hasClass('fl-menu-responsive-flyout-push')||menuModule.hasClass('fl-menu-responsive-flyout-push-opacity'),isOverlay=menuModule.hasClass('fl-menu-responsive-flyout-overlay'),flyoutPos=menuModule.hasClass('fl-flyout-right')?'right':'left',flyoutParent=header.parent().is('header')?header.parent().parent():header.parent();isFullWidth=this.win.width()===header.width(),flyoutLayout='',activePos=250,headerPos=0;if(!flyoutMenu.length){return;} if(this.win.width()>header.parent().width()){headerPos=(this.win.width()-header.width())/ 2;} if(isOverlay){activePos=headerPos;} else 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