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PDB-101: Video Challenge

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onclick="location.href=&quot;/events/video-challenge/2022-awards&quot;" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">2022 Awards</div> <div class="pdb101-left-menu-item-chevron"><span class="fa fa-chevron-right fade"></span></div> </div> <div onclick="location.href=&quot;/events/video-challenge/2021-awards&quot;" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">2021 Awards</div> <div class="pdb101-left-menu-item-chevron"><span class="fa fa-chevron-right fade"></span></div> </div> <div onclick="location.href=&quot;/events/video-challenge/2020-awards&quot;" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">2020 Awards</div> <div class="pdb101-left-menu-item-chevron"><span class="fa fa-chevron-right fade"></span></div> </div> <div onclick="location.href=&quot;/events/video-challenge/2019-awards&quot;" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">2019 Awards</div> <div class="pdb101-left-menu-item-chevron"><span class="fa fa-chevron-right fade"></span></div> </div> <div onclick="location.href=&quot;/events/video-challenge/2018-awards&quot;" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">2018 Awards</div> <div class="pdb101-left-menu-item-chevron"><span class="fa fa-chevron-right fade"></span></div> </div> <div onclick="location.href=&quot;/events/video-challenge/2017-awards&quot;" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">2017 Awards</div> <div class="pdb101-left-menu-item-chevron"><span class="fa fa-chevron-right fade"></span></div> </div> <div onclick="location.href=&quot;/events/video-challenge/2016-awards&quot;" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">2016 Awards</div> <div class="pdb101-left-menu-item-chevron"><span class="fa fa-chevron-right fade"></span></div> </div> <div onclick="location.href=&quot;/events/video-challenge/2015-awards&quot;" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">2015 Awards</div> <div class="pdb101-left-menu-item-chevron"><span class="fa fa-chevron-right fade"></span></div> </div> <div onclick="location.href=&quot;/events/video-challenge/2014-awards&quot;" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">2014 Awards</div> <div class="pdb101-left-menu-item-chevron"><span class="fa fa-chevron-right fade"></span></div> </div> </div> </div> <div class="col-sm-12 col-md-9 pdb101-page-content"> <style> .rowMargin{ margin-top: 10px;; padding-top: 10px; border-top: 1px solid #ddd; } .noPadLeft{ padding-left: 0; } </style> <h1>Video Challenge for High School Students</h1> <p><em>An annual competition held 2014-2023</em></p> <p>For 10 years, PDB-101 has hosted a Video Challenge that demonstrated how high school students are excellent science communicators. Teams from across the United States created videos that using tremendous creativity and many storytelling approaches to communicate how PDB structures help our understanding of HIV, Diabetes, Anti-microbial Resistance, Opioids, and Cancer.</p> <p>Since the inaugural event in 2014, 376 videos have been created by more than one thousand high school students.</p> <p>The videos were reviewed by expert judges. Click on the <em>Judges</em> link below to see the criteria for each year. A winner and two runner-ups were selected each year. In addition, the general public voted for the Viewer's Choice Award.</p> <p><strong>Many thanks to the expert judges, students, teachers, parents, and voters who made this exciting competition happen for so many years.</strong></p> <p>Explore the annual events using the section below.</p> <div id="onediv"></div> <script> const videoChallenge = [ { year: '2023', topic: 'Molecular Mechanisms of Targeted Cancer Therapies', image: 'header-23.jpg' }, { year: '2022', topic: 'Molecular Mechanisms of Cancer', image: 'header-22.jpg' }, { year: '2021', topic: 'Molecular Mechanisms of Drugs for Mental Disorders', image: 'header-21.jpg' }, { year: '2020', topic: 'Molecular Mechanisms of Opioid Action', image: 'header-20.jpg' }, { year: '2019', topic: 'Mechanisms of Bacterial Resistance to Aminoglycoside Antibiotics', image: 'header-19.jpg' }, { year: '2018', topic: 'Mechanisms of Bacterial Resistance to Beta-lactam Antibiotics', image: 'header-18.jpg' }, { year: '2017', topic: 'Molecular View of Diabetes Treatment and Management', image: 'header-17.jpg' }, { year: '2016', topic: 'Structural Biology & Diabetes', image: 'header-16.jpg' }, { year: '2015', topic: 'Detecting & Combating HIV in 3D', image: 'header-15.jpg' }, { year: '2014', topic: 'Structural View of HIV/AIDS', image: 'header-14.jpg' }, ] const onediv= document.getElementById("onediv") for(i=0; i<videoChallenge.length; i++){ const eachRow = document.createElement('div'); eachRow.className = 'row rowMargin'; onediv.appendChild(eachRow) const imageDiv = document.createElement('div'); imageDiv.className = 'col-xs-2'; eachRow.appendChild(imageDiv) var themeImage = document.createElement('img'); Object.assign(themeImage, { className: 'img-responsive', src: 'https://cdn.rcsb.org/pdb101/events/video-challenge/images/'+videoChallenge[i].image, alt: "Decorative Icon" }) imageDiv.appendChild(themeImage) const textDiv = document.createElement('div'); textDiv.className = 'col-xs-10 noPadLeft'; textDiv.innerHTML = `<h4>${videoChallenge[i].year}: ${videoChallenge[i].topic}</h4> <p><a href="/events/video-challenge/${videoChallenge[i].year}-awards">Winners</a> | <a href="/events/video-challenge/submissions/${videoChallenge[i].year}">Entries</a> | <a href="/events/video-challenge/judges-${videoChallenge[i].year}">Judges</a> | <a href="/events/video-challenge/${videoChallenge[i].year}-awards#intro">Overview</a> | <a href="/events/video-challenge/${videoChallenge[i].year}-awards#learningResources">Learning Resources</a></p>` eachRow.appendChild(textDiv) } </script> <!-- <style> .indented{ padding-left: 30px; } </style> <h1>2023 Challenge Description</h1> <div class="col-xs-4 pull-right"><a href="https://cdn.rcsb.org/pdb101/events/video-challenge/flyer-2023.pdf"><img src="https://cdn.rcsb.org/pdb101/events/video-challenge/images/flyer-2023.png" class="img-responsive border"/></a> <a href="https://cdn.rcsb.org/pdb101/events/video-challenge/flyer-2023.pdf" target="_blank">A PDF flyer describing this challenge is available for download and distribution.</a> </div> <p>Cancer cells are normal human cells that multiply faster due to mutations in the key genes that regulate the protein division and growth. The traditional cancer chemotherapies that have been in use since the 1940s target all fast-growing and dividing cells. As cancer researchers learn more and more about the genetic mechanisms driving the disease, they design therapies that target specific proteins in cancer cells. These therapies are referred to as Targeted Cancer Therapies. Most drugs used targeted therapies are monoclonal antibodies (antibodies developed in the lab), or small molecules. </p> <p>In the 2023 challenge you will research one of the examples of targeted therapies listed below:</p> <ol> <li>Fighting breast cancer by targeting HER2 receptor</li> <li>Preventing blood vessel formation in tumors by targeting VegF </li> <li>Interrupting cancer cell growth by targeting the G12C variant of ras protein </li> </ol> <p>Then you will create a video entry that tells a coherent story that communicates the following components to the viewers:</p> <ul> <li> A brief introduction to the concept of targeted therapy </li> <li>A brief introduction to the structure and function of the targeted protein</li> <li>An explanation of the molecular mechanism by which the cancer cells respond to targeted therapy</li> </ul> <p>Imagine you are teaching this content to another high school student, whose overall knowledge of biology is similar to yours, but has not studied the molecular pathways leading to cell division.</p> <p>In order to qualify to win the challenge, the entry must fulfill the following requirements:</p> <ul> <li> The entry must include a molecular visualization of the target protein and the target protein/drug complex using examples from the Protein Data Bank Archive (see <a href="learn#table1">Table 1</a>, <a href="learn#table2">Table 2</a>, and <a href="learn#table3">Table 3</a> in the <a href="learn">Learn</a> section) </li> <li> The storytelling part is no longer than 2 minutes </li> <li> The title represents the video's story </li> <li> Included narration is at natural speed, not artificially sped up </li> <li> The entry doesn&rsquo;t contain any copyrighted materials </li> <li> The entry concludes with a credits section that lists the references to all research materials, citations of the PDB structures shown, and image and sound credits (can run in addition to the 2 minutes allotted for storytelling). </li> <li> The video ends with the<a href="https://cdn.rcsb.org/pdb101/events/video-challenge/images/pdb101-slide.png"> PDB-101 branding slide</a> </li> </ul> <p>Refer to the<a href="/events/video-challenge/rules"> Rules</a> section for more details. Refer to the <a href="learn">Learn</a> section for topic overview, links to further resources, and examples of topic-relevant PDB structures. </p> <h3>Who can participate?</h3> <p>All students enrolled in any high school in the United States and equivalent level home-schooled students are eligible to participate in groups comprising from 1 to 4 students. Each participant has to submit the <a href="https://cdn.rcsb.org/pdb101/events/video-challenge/parent-permission.pdf">Permission Form</a>. Entries lacking signed permission forms will be disqualified. Refer to the <a href="participate">Participate</a> and <a href="rules">Rules</a> sections for more details.</span></p> <hr /> <a class="anchor" name="timeline"></a> <h3>Important Dates</h3> <table class='important-dates'> <tbody> <tr> <td width="174" class='important-dates-label'>Submission Opens</td> <td width="555">January 17, 2023</td> </tr> <tr> <td width="174" class='important-dates-label'>Submission Closes</td> <td width="555">April 24, 2023 at 11:59 pm PST</td> </tr> <tr> <td class='important-dates-label'>Judging and Voting</td> <td>May 2 - May 8, 2023</td> </tr> <tr> <td class='important-dates-label'>Results</td> <td>Award winners will be announced at rcsb.org and pdb101.rcsb.org on May 16, 2023.</td> </tr> </tbody> </table> <hr /> <h3>Awards</h3> <div class="col-xs-4 pull-right"><a href="https://cdn.rcsb.org/pdb101/events/video-challenge/judging-criteria.pdf"><img src="https://cdn.rcsb.org/pdb101/events/video-challenge/images/criteria.png" class="img-responsive border"/></a> <a href="https://cdn.rcsb.org/pdb101/events/video-challenge/judging-criteria.pdf" target="_blank">Detailed description of judging criteria</a> </div> <p>All qualifying entries will be eligible to win one or more of the following:</p> <h5>Judge's Award</h5> <p>A panel of <a href="judges">expert judges </a>will review the videos. All qualified entries will be judged on the following criteria (<a href="https://cdn.rcsb.org/pdb101/events/video-challenge/judging-criteria.pdf">see the detailed description of each criterion</a>): </p> <ul> <li>Quality of Narrative Storytelling 30% </li> <li>Quality of Science Communication 30%</li> <li>Originality and Creativity 20% </li> <li>Quality of Production 10%</li> <li>Proper Accreditation 10%</li> </ul> <h5>Viewer's Choice Award</h5> <p>As voted by the viewers.</p> <p>The winning entries will be recognized on rcsb.org, pdb101.rcsb.org, and in an upcoming <a href="http://www.rcsb.org/pdb/static.do?p=general_information/news_publications/newsletters/newsletter.html" target="_blank">RCSB PDB Newsletter</a>.</p> --> </div> </div> </div> <div id="footer_main" class="hidden-print"> <div class="container"> <div class="row"> <div class="col-sm-12 col-md-7"> <p><strong>About PDB-101</strong></p> <p>Researchers around the globe make 3D structures freely available from the Protein Data Bank (PDB) archive. PDB-101 training materials help graduate students, postdoctoral scholars, and researchers use PDB data and RCSB PDB tools. Outreach content demonstrate how PDB data impact fundamental biology, biomedicine, bioengineering/biotechnology, and energy sciences in 3D for a diverse and multidisciplinary user community. Education Materials provide lessons and activities for teaching and learning.</p> <p>PDB-101 is developed by the <a href="https://rcsb.org" target="_blank">RCSB PDB</a>.</p> </div> <div class="col-sm-12 col-md-5 text-center"> <p>RCSB PDB (<a href="http://nar.oxfordjournals.org/content/28/1/235.abstract" target="blank">citation</a>) is hosted by</p><img src="//cdn.rcsb.org/pdb101/common/images/Logo_Rutgers-2024.png" alt="Rutgers University logo" usemap="#rutgers-map" height="32" style="padding:0px 10px; border-right: 1px solid #000000;"><img src="//cdn.rcsb.org/pdb101/common/images/Logo_UCSD-SDSC.png" alt="University of California San Diego/San Diego Supercomputer Center logos" usemap="#UCSD-SDSC-map" height="26" style="padding: 0px 10px; border-right: 1px solid #000000;"><img src="//cdn.rcsb.org/pdb101/common/images/Logo_UCSF.png" alt="Univesity of California San Franciscologo" usemap="#UCSF-map" height="26" style="padding-left: 10px;"><map name="rutgers-map"> <area shape="rect" coords="0,0,115,26" href="http://www.rutgers.edu/" alt="Rutgers" target="_blank"></map><map name="UCSD-SDSC-map"> <area shape="rect" coords="0,0,150,26" href="http://ucsd.edu/" alt="UCSD" target="_blank"> <area shape="rect" coords="151,0,255,26" href="http://www.sdsc.edu/" alt="SDSC" target="_blank"></map><map name="UCSF-map"> <area shape="rect" coords="0,0,64,26" href="http://www.ucsf.edu/" alt="UCSF" target="_blank"></map><br><br> <p>RCSB PDB is a member of <span id='pdbmembers_footer'><a href='http://www.wwpdb.org/' target='_blank'><img src='//cdn.rcsb.org/pdb101/common/images/Logo_wwpdb.png' width='70'></a><span class='pipe'></span><a href='http://www.emdatabank.org/' target='_blank'><img src='https://cdn.rcsb.org/pdb101/common/images/EMDataResourcelogo.png' width='100'></a></p> </div> </div> </div> </div> <div id="footer_grant" class="hidden-print"> <div class="container"> <div class="row"> <p>RCSB PDB Core Operations are funded by the <a href="http://www.nsf.gov/" target="_blank">U.S. National Science Foundation</a> (DBI-2321666), the <a href="http://science.energy.gov/" target="_blank">US Department of Energy</a> (DE-SC0019749), and the <a href="http://www.cancer.gov/" target="_blank">National Cancer Institute</a>, <a href="http://www.niaid.nih.gov/" target="_blank">National Institute of Allergy and Infectious Diseases</a>, and <a href="http://www.nigms.nih.gov/" target="_blank">National Institute of General Medical Sciences</a> of the <a href="http://www.nih.gov/" target="_blank">National Institutes of Health</a> under grant R01GM157729.</p> </div> </div> </div> <div id="jira-fdbck"></div><script> //Google Analytics tracking code {/* (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){ (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) })(window,document,'script','//www.google-analytics.com/analytics.js','ga'); ga('create', 'UA-71059016-1', 'auto'); ga('send', 'pageview'); */} </script> </div> </body> </html>

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