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[r]" accesskey="r"><span>Nedavne izmjene</span></a></li><li id="n-randompage" class="mw-list-item"><a href="/wiki/Posebno:Nasumi%C4%8Dna_stranica" title="Učitaj nasumičnu stranicu [x]" accesskey="x"><span>Nasumična stranica</span></a></li> </ul> </div> </div> <div id="p-interaction" class="vector-menu mw-portlet mw-portlet-interaction" > <div class="vector-menu-heading"> Interakcija </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="n-help" class="mw-list-item"><a href="/wiki/Pomo%C4%87:Sadr%C5%BEaj" title="Mjesto gdje možete nešto da naučite."><span>Pomoć</span></a></li><li id="n-sidebar-sandbox" class="mw-list-item"><a href="/wiki/Wikipedia:Igrali%C5%A1te"><span>Igralište</span></a></li><li id="n-portal" class="mw-list-item"><a href="/wiki/Wikipedia:Vrata_zajednice" title="O projektu, šta možete da uradite, gdje se šta nalazi"><span>Vrata zajednice</span></a></li><li id="n-sidebar-village-pump" class="mw-list-item"><a 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class="vector-menu-content-list"> <li id="pt-sitesupport-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_bs.wikipedia.org&uselang=bs" class=""><span>Donacije</span></a> </li> <li id="pt-createaccount-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Posebno:Napravi_ra%C4%8Dun&returnto=SCN1A" title="Predlažemo vam da napravite račun i prijavite se; međutim, to nije obavezno" class=""><span>Napravi korisnički račun</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=Posebno:Korisni%C4%8Dka_prijava&returnto=SCN1A" title="Predlažemo vam da se prijavite, iako to nije obavezno [o]" accesskey="o" class=""><span>Prijavi me</span></a> </li> 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me</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> Stranice za odjavljene urednike <a href="/wiki/Pomo%C4%87:Uvod" aria-label="Saznajte više o uređivanju"><span>detaljnije</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Posebno:Moji_doprinosi" title="Spisak izmjena napravljenih s ove IP-adrese [y]" accesskey="y"><span>Doprinosi</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Posebno:Moj_razgovor" title="Rasprava o izmjenama s ove IP-adrese [n]" accesskey="n"><span>Razgovor</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"><div 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id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Sadržaj" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Sadržaj</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">sakrij</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Početak</div> </a> </li> <li id="toc-Lokacija_gena" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Lokacija_gena"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Lokacija gena</span> </div> </a> <ul id="toc-Lokacija_gena-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Aminokiselinska_sekvenca" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Aminokiselinska_sekvenca"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Aminokiselinska sekvenca</span> </div> </a> <ul id="toc-Aminokiselinska_sekvenca-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Funkcija" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Funkcija"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Funkcija</span> </div> </a> <ul id="toc-Funkcija-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Klinički_značaj" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Klinički_značaj"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Klinički značaj</span> </div> </a> <ul id="toc-Klinički_značaj-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Interakcije" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Interakcije"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Interakcije</span> </div> </a> <ul id="toc-Interakcije-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Također_pogledajte" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Također_pogledajte"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Također pogledajte</span> </div> </a> <ul id="toc-Također_pogledajte-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reference" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Reference"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Reference</span> </div> </a> <ul id="toc-Reference-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Dopunska_literatura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Dopunska_literatura"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>Dopunska literatura</span> </div> </a> <ul id="toc-Dopunska_literatura-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Vanjski_linkovi" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Vanjski_linkovi"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>Vanjski linkovi</span> </div> </a> <ul id="toc-Vanjski_linkovi-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Sadržaj" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Uključi/isključi sadržaj" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Uključi/isključi sadržaj</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading">SCN1A</h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Idi na članak na drugom jeziku. Dostupno na 4 jezika" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-4" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">4 jezika</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/SCN1A" title="SCN1A – engleski" lang="en" hreflang="en" data-title="SCN1A" data-language-autonym="English" data-language-local-name="engleski" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/Nav1.1" title="Nav1.1 – perzijski" lang="fa" hreflang="fa" data-title="Nav1.1" data-language-autonym="فارسی" data-language-local-name="perzijski" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/SCN1A" title="SCN1A – francuski" lang="fr" hreflang="fr" data-title="SCN1A" data-language-autonym="Français" data-language-local-name="francuski" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/SCN1A" title="SCN1A – ukrajinski" lang="uk" hreflang="uk" data-title="SCN1A" data-language-autonym="Українська" data-language-local-name="ukrajinski" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q18031391#sitelinks-wikipedia" title="Uredi međujezičke linkove" class="wbc-editpage">Uredi veze</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Imenski prostori"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/SCN1A" title="Prikaži stranicu sa sadržajem [c]" accesskey="c"><span>Stranica</span></a></li><li id="ca-talk" class="new vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Razgovor:SCN1A&action=edit&redlink=1" rel="discussion" class="new" title="Razgovor o sadržaju (stranica ne postoji) [r]" accesskey="r"><span>Razgovor</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Promijeni varijantu jezika" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">bosanski</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Pregledi"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/SCN1A"><span>Čitaj</span></a></li><li id="ca-ve-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=SCN1A&veaction=edit" title="Uredite ovu stranicu [v]" accesskey="v"><span>Uredi</span></a></li><li id="ca-edit" class="collapsible vector-tab-noicon mw-list-item"><a href="/w/index.php?title=SCN1A&action=edit" title="Uredite izvorni kod ove stranice [e]" accesskey="e"><span>Uredi izvor</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=SCN1A&action=history" title="Prethodne izmjene ove stranice [h]" accesskey="h"><span>Historija</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Alati" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Alati</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Alati</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">sakrij</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="More options" > <div class="vector-menu-heading"> Radnje </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/SCN1A"><span>Čitaj</span></a></li><li id="ca-more-ve-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=SCN1A&veaction=edit" title="Uredite ovu stranicu [v]" accesskey="v"><span>Uredi</span></a></li><li id="ca-more-edit" class="collapsible vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=SCN1A&action=edit" title="Uredite izvorni kod ove stranice [e]" accesskey="e"><span>Uredi izvor</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=SCN1A&action=history"><span>Historija</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> Općenito </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Posebno:%C5%A0ta_vodi_ovamo/SCN1A" title="Spisak svih članaka koji su povezani s ovim [j]" accesskey="j"><span>Šta vodi ovamo</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Posebno:Srodne_izmjene/SCN1A" rel="nofollow" title="Nedavne izmjene na stranicama koje su povezane sa ovom [k]" accesskey="k"><span>Srodne izmjene</span></a></li><li id="t-upload" class="mw-list-item"><a href="/wiki/Wikipedia:Upload" title="Postavi slike i druge medije [u]" accesskey="u"><span>Postavi datoteku</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Posebno:Posebne_stranice" title="Spisak svih posebnih stranica [q]" accesskey="q"><span>Posebne stranice</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=SCN1A&oldid=3534928" title="Trajni link ove verzije stranice"><span>Trajni link</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=SCN1A&action=info" title="Više informacija o ovoj stranici"><span>Informacije o stranici</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Posebno:Citiraj&page=SCN1A&id=3534928&wpFormIdentifier=titleform" title="Informacije kako citirati ovu stranicu"><span>Citiraj ovu stranicu</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Posebno:Skra%C4%87iva%C4%8D_adresa&url=https%3A%2F%2Fbs.wikipedia.org%2Fwiki%2FSCN1A"><span>Skraćeni link</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Posebno:QrCode&url=https%3A%2F%2Fbs.wikipedia.org%2Fwiki%2FSCN1A"><span>Preuzmi QR kod</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Štampanje / izvoz </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=Posebno:Kolekcija&bookcmd=book_creator&referer=SCN1A"><span>Napravi knjigu</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Posebno:DownloadAsPdf&page=SCN1A&action=show-download-screen"><span>Preuzmi kao PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=SCN1A&printable=yes" title="Verzija ove stranice za štampanje [p]" accesskey="p"><span>Za štampanje</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> Na drugim projektima </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q18031391" title="Link na povezane podatke spremišnih stavki [g]" accesskey="g"><span>Stavka na Wikipodacima</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Page tools"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Izgled"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Izgled</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">premjesti na bočnu traku</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">sakrij</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">S Wikipedije, slobodne enciklopedije</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="bs" dir="ltr"><table class="infobox" style="width:26.4em"><tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">SCN1A</th></tr><tr><td colspan="4" style="text-align:center"><span typeof="mw:File"><a href="/wiki/Datoteka:SCN1A.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/SCN1A.png/250px-SCN1A.png" decoding="async" width="250" height="127" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/SCN1A.png/375px-SCN1A.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2d/SCN1A.png/500px-SCN1A.png 2x" data-file-width="1920" data-file-height="975" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Dostupne strukture</th></tr><tr><th rowspan="2" style="background-color:#c3fdb8;width:43px"><a href="/wiki/Proteinska_banka_podataka" title="Proteinska banka podataka">PDB</a></th><td colspan="2" style="background-color:#eee">Pretraga ortologa: <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/searchResults.html?display=both&term=A2APX8%20or%20P35498">PDBe</a> <a rel="nofollow" class="external text" href="https://www.rcsb.org/search?q=rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_name:UniProt%20AND%20rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_accession:A2APX8,P35498">RCSB</a> </span></td></tr><tr><td><table class="mw-collapsible mw-collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr style="background-color:#ddd;text-align:center"><th colspan="2">Spisak PDB ID kodova</th></tr><tr><td colspan="2" style="background-color:#eee"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/7DTD">7DTD</a></span></p></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ddd">Identifikatori</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><span class="plainlinks"><a href="/wiki/Nomenklatura_gena" class="mw-redirect" title="Nomenklatura gena">Aliasi</a></span></th><td colspan="3" style="background:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/10585">SCN1A</a></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">Vanjski ID-jevi</th><td colspan="3" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/OMIM" title="OMIM">OMIM</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/182389">182389</a> <a href="/wiki/Informatika_o_mi%C5%A1jem_genomu" title="Informatika o mišjem genomu">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:98246">98246</a> <a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=21375">21375</a> <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <a rel="nofollow" class="external text" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=SCN1A">SCN1A</a> </span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="mw-collapsible mw-collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Lokacija gena (<a href="/wiki/Ljudski_genom" title="Ljudski genom">čovjek</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/Datoteka:Ideogram_human_chromosome_2.svg" class="mw-file-description" title="Hromosom 2 (čovjek)"><img alt="Hromosom 2 (čovjek)" src="//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/300px-Ideogram_human_chromosome_2.svg.png" decoding="async" width="300" height="120" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/450px-Ideogram_human_chromosome_2.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/600px-Ideogram_human_chromosome_2.svg.png 2x" data-file-width="474" data-file-height="189" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Hromosom" title="Hromosom">Hrom.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Hromosom_2_(%C4%8Dovjek)" class="mw-redirect" title="Hromosom 2 (čovjek)">Hromosom 2 (čovjek)</a><sup id="cite_ref-refGRCh38Ensembl_1-0" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/Datoteka:Human_chromosome_2_ideogram.svg" class="mw-file-description" title="Hromosom 2 (čovjek)"><img alt="Hromosom 2 (čovjek)" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/77/Human_chromosome_2_ideogram.svg/300px-Human_chromosome_2_ideogram.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/77/Human_chromosome_2_ideogram.svg/450px-Human_chromosome_2_ideogram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/77/Human_chromosome_2_ideogram.svg/600px-Human_chromosome_2_ideogram.svg.png 2x" data-file-width="1125" data-file-height="216" /></a></span><div style="position: absolute; left: 196.28085002693px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/Datoteka:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomska lokacija za SCN1A"><img alt="Genomska lokacija za SCN1A" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 202.3px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/Datoteka:Red_rectangle_2x18.png" class="mw-file-description" title="Genomska lokacija za SCN1A"><img alt="Genomska lokacija za SCN1A" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Lokus_(gen)" title="Lokus (gen)">Bend</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">2q24.3</span></td><th scope="row" style="background-color:#c3fdb8">Početak</th><td style="background-color:#eee"><span class="plainlinks">165,984,641 <a href="/wiki/Bazni_par" title="Bazni par">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-1" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">Kraj</th><td style="background-color:#eee"><span class="plainlinks">166,149,214 <a href="/wiki/Bazni_par" title="Bazni par">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-2" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="mw-collapsible mw-collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Lokacija gena (<a href="/wiki/Laboratorijski_mi%C5%A1" title="Laboratorijski miš">miš</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/Datoteka:Ideogram_house_mouse_chromosome_2.svg" class="mw-file-description" title="Hromosom 2 (miš)"><img alt="Hromosom 2 (miš)" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Ideogram_house_mouse_chromosome_2.svg/260px-Ideogram_house_mouse_chromosome_2.svg.png" decoding="async" width="260" height="111" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Ideogram_house_mouse_chromosome_2.svg/390px-Ideogram_house_mouse_chromosome_2.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Ideogram_house_mouse_chromosome_2.svg/520px-Ideogram_house_mouse_chromosome_2.svg.png 2x" data-file-width="470" data-file-height="200" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Hromosom" title="Hromosom">Hrom.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks">Hromosom 2 (miš)<sup id="cite_ref-refGRCm38Ensembl_2-0" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/Datoteka:Ideogram_of_house_mouse_chromosome_2.svg" class="mw-file-description" title="Hromosom 2 (miš)"><img alt="Hromosom 2 (miš)" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b4/Ideogram_of_house_mouse_chromosome_2.svg/300px-Ideogram_of_house_mouse_chromosome_2.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b4/Ideogram_of_house_mouse_chromosome_2.svg/450px-Ideogram_of_house_mouse_chromosome_2.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b4/Ideogram_of_house_mouse_chromosome_2.svg/600px-Ideogram_of_house_mouse_chromosome_2.svg.png 2x" data-file-width="1200" data-file-height="231" /></a></span><div style="position: absolute; left: 101.49803052182px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/Datoteka:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomska lokacija za SCN1A"><img alt="Genomska lokacija za SCN1A" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 107.5px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/Datoteka:Red_rectangle_2x18.png" class="mw-file-description" title="Genomska lokacija za SCN1A"><img alt="Genomska lokacija za SCN1A" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Lokus_(gen)" title="Lokus (gen)">Bend</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">2 C1.3|2 39.13 cM</span></td><th scope="row" style="background-color:#c3fdb8">Početak</th><td style="background-color:#eee"><span class="plainlinks">66,101,122 <a href="/wiki/Bazni_par" title="Bazni par">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-1" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">Kraj</th><td style="background-color:#eee"><span class="plainlinks">66,271,184 <a href="/wiki/Bazni_par" title="Bazni par">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-2" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="mw-collapsible mw-collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Obrazac <a href="/wiki/Ekspresija_gena" title="Ekspresija gena">RNK ekspresije</a></th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/Datoteka:PBB_GE_SCN1A_210383_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/2/22/PBB_GE_SCN1A_210383_at_fs.png/250px-PBB_GE_SCN1A_210383_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/22/PBB_GE_SCN1A_210383_at_fs.png/375px-PBB_GE_SCN1A_210383_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/22/PBB_GE_SCN1A_210383_at_fs.png/500px-PBB_GE_SCN1A_210383_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/6323/">Više referentnih podataka o ekspresiji</a></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="mw-collapsible mw-collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Ontologija_gena" title="Ontologija gena">Ontologija gena</a></th></tr><tr><th style="background-color:#c3fdb8">Molekularna funkcija</th><td style="background-color:#eee"><span class="plainlinks"><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005272">sodium channel activity</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005244">voltage-gated ion channel activity</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005216">ion channel activity</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005248">voltage-gated sodium channel activity</a><br /></span></td></tr><tr><th style="background-color:#c3fdb8">Ćelijska komponenta</th><td style="background-color:#eee"><span class="plainlinks"><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0001518">voltage-gated sodium channel complex</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016021">integral component of membrane</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016020">membrana</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005654">nukleoplazma</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005886">ćelijska membrana</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016604">nuclear body</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0014704">Interkalirani disk</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030018">Z discdkac</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030315">T-tubule</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030424">Akson</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0033268">Ranvijerov čvor</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0034706">sodium channel complex</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043025">soma</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043194">axon initial segment</a><br /></span></td></tr><tr><th style="background-color:#c3fdb8">Biološki proces</th><td style="background-color:#eee"><span class="plainlinks"><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0086010">membrane depolarization during action potential</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0035725">sodium ion transmembrane transport</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0034765">regulation of ion transmembrane transport</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006811">ion transport</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0055085">transmembrane transport</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0034220">ion transmembrane transport</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006814">sodium ion transport</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0086002">cardiac muscle cell action potential involved in contraction</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0001508">Akcijski potencijal</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007628">adult walking behavior</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0019227">neuronal action potential propagation</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0019228">neuronal action potential</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0042391">regulation of membrane potential</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050884">neuromuscular process controlling posture</a><br /><big>•</big> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050966">detection of mechanical stimulus involved in sensory perception of pain</a><br /></span></td></tr><tr><td colspan="4" style="background-color:#eee;text-align:center">Izvori:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Homologija_sekvence#Ortologija" title="Homologija sekvence">Ortolozi</a></th></tr><tr><th scope="row" style="background-color:#c3fdb8">Vrste</th><td><b>Čovjek</b></td><td><b>Miš</b></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=6323&rn=1">6323</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=20265&rn=1">20265</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000144285;db=core">ENSG00000144285</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000064329;db=core">ENSMUSG00000064329</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P35498">P35498</a></p></td></tr></tbody></table></td><td><table style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/A2APX8">A2APX8</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (mRNK)</th><td><table class="mw-collapsible mw-collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001165963">NM_001165963</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001165964">NM_001165964</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001202435">NM_001202435</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_006920">NM_006920</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353948">NM_001353948</a><br /></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353949">NM_001353949</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353950">NM_001353950</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353951">NM_001353951</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353952">NM_001353952</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353954">NM_001353954</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353955">NM_001353955</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353957">NM_001353957</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353958">NM_001353958</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353960">NM_001353960</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001353961">NM_001353961</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_018733">NM_018733</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001313997">NM_001313997</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (bjelančevina)</th><td><table class="mw-collapsible mw-collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001159435">NP_001159435</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001159436">NP_001159436</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001189364">NP_001189364</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_008851">NP_008851</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340877">NP_001340877</a><br /></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340878">NP_001340878</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340879">NP_001340879</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340880">NP_001340880</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340881">NP_001340881</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340883">NP_001340883</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340884">NP_001340884</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340886">NP_001340886</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340887">NP_001340887</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340889">NP_001340889</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001340890">NP_001340890</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001300926">NP_001300926</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_061203">NP_061203</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">Lokacija (UCSC)</th><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg38&position=chr2:165984641-166149214">Chr 2: 165.98 – 166.15 Mb</a></span></td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm0&position=chr2:66101122-66271184">Chr 2: 66.1 – 66.27 Mb</a></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/PubMed" title="PubMed">PubMed</a> pretraga</th><td><span class="plainlinks"><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></span></td><td><span class="plainlinks"><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;font-size:x-small;background-color:#eee"><a href="/wiki/Wikipodaci" title="Wikipodaci">Wikipodaci</a></td></tr><tr><td colspan="4" style="text-align:center;font-size:x-small;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:#eee;text-align:center;font-size:x-small"><a href="https://www.wikidata.org/wiki/Q18031391" class="extiw" title="d:Q18031391">Pogledaj/uredi – čovjek</a></td><td colspan="2" style="background-color:#eee;text-align:center;font-size:x-small"><a href="https://www.wikidata.org/wiki/Q18253948" class="extiw" title="d:Q18253948">Pogledaj/uredi – miš</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>Podjedinica alfa proteinskog tipa 1 <a href="/wiki/Natrijski_kanal" title="Natrijski kanal">natrijskog kanala</a> </b> (<b>SCN1A</b>), jest <a href="/wiki/Protein" class="mw-redirect" title="Protein">protein</a> koji je kod <a href="/wiki/Ljudi" class="mw-redirect" title="Ljudi">ljudi</a> <a href="/wiki/Kodon" title="Kodon">kodiran</a> <a href="/wiki/Gen" title="Gen">genom</a> <b>SCN1A</b> sa <a href="/wiki/Hromosom_2" title="Hromosom 2">hromosoma 2</a>.<sup id="cite_ref-entrez_5-0" class="reference"><a href="#cite_note-entrez-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid8062593_6-0" class="reference"><a href="#cite_note-pmid8062593-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid11823106_7-0" class="reference"><a href="#cite_note-pmid11823106-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid16382098_8-0" class="reference"><a href="#cite_note-pmid16382098-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Lokacija_gena">Lokacija gena</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SCN1A&veaction=edit&section=1" title="Uredi odlomak "Lokacija gena"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=SCN1A&action=edit&section=1" title="Edit section's source code: Lokacija gena"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Kodljudi, <a href="/wiki/Gen" title="Gen">gen</a> <b>SCN1A</b> nalazi se na hromosomu 2, i sastoji se od 26 <a href="/wiki/Egzon" title="Egzon">egzona</a> koji obuhvataju ukupnu dužinu od 6.030 parova <a href="/wiki/Nukleotid" title="Nukleotid">nukleotidnih</a> baza (bp).<sup id="cite_ref-:0_9-0" class="reference"><a href="#cite_note-:0-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-:1_10-0" class="reference"><a href="#cite_note-:1-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> <a href="/wiki/Alternativna_prerada_RNK" title="Alternativna prerada RNK">Alternativna prerada</a> egzona 5 dovodi do dva alternativna egzona.<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> <a href="/wiki/Promotor_(genetika)" title="Promotor (genetika)">Promotor</a> je identificiran 2,5 kilobaznih parova (kb) uzvodno od mjesta početka transkripcije, a 5'-netranslirani egzoni mogu poboljšati ekspresiju gena SCN1A u SH-SY5Y ćelijama, ljudske <a href="/wiki/Kultura_%C4%87elija" title="Kultura ćelija">ćelijske linije</a> izvedenoj od <a href="/w/index.php?title=Neuroblastom&action=edit&redlink=1" class="new" title="Neuroblastom (stranica ne postoji)">neuroblastoma</a>.<sup id="cite_ref-:2_12-0" class="reference"><a href="#cite_note-:2-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Aminokiselinska_sekvenca">Aminokiselinska sekvenca</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SCN1A&veaction=edit&section=2" title="Uredi odlomak "Aminokiselinska sekvenca"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=SCN1A&action=edit&section=2" title="Edit section's source code: Aminokiselinska sekvenca"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Dužina <a href="/wiki/Polipeptid" class="mw-redirect" title="Polipeptid">polipeptidnog</a> lanca je 2.009 <a href="/wiki/Aminokiselina" title="Aminokiselina">aminokiselina</a>, a <a href="/wiki/Molekularna_masa" class="mw-redirect" title="Molekularna masa">molekulska težina</a> 228.972 <a href="/wiki/Dalton_(jedinica)" class="mw-redirect" title="Dalton (jedinica)">Da</a>.<sup id="cite_ref-entrez_5-1" class="reference"><a href="#cite_note-entrez-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p> <style data-mw-deduplicate="TemplateStyles:r3312387">.mw-parser-output .div-col{margin-top:0.3em;column-width:30em}.mw-parser-output .div-col-small{font-size:90%}.mw-parser-output .div-col-rules{column-rule:1px solid #aaa}.mw-parser-output .div-col dl,.mw-parser-output .div-col ol,.mw-parser-output .div-col ul{margin-top:0}.mw-parser-output .div-col li,.mw-parser-output .div-col dd{page-break-inside:avoid;break-inside:avoid-column}</style><div class="div-col" style="column-width: 25em;"> <p><small> </small></p><small> </small><ul><small><li><b>C</b>: <a href="/wiki/Cistein" title="Cistein">Cistein</a></li> <li><b>D</b>: <a href="/wiki/Asparaginska_kiselina" title="Asparaginska kiselina">Asparaginska kiselina</a></li> <li><b>E</b>: <a href="/wiki/Glutaminska_kiselina" title="Glutaminska kiselina">Glutaminska kiselina</a></li> <li><b>F</b>: <a href="/wiki/Fenilalanin" title="Fenilalanin">Fenilalanin</a></li> <li><b>G</b>: <a href="/wiki/Glicin" title="Glicin">Glicin</a></li> <li><b>H</b>: <a href="/wiki/Histidin" title="Histidin">Histidin</a></li> <li><b>I</b>: <a href="/wiki/Izoleucin" title="Izoleucin">Izoleucin</a></li> <li><b>K</b>: <a href="/wiki/Lizin" class="mw-redirect" title="Lizin">Lizin</a></li> <li><b>L</b>: <a href="/wiki/Leucin" title="Leucin">Leucin</a></li> <li><b>M</b>: <a href="/wiki/Metionin" title="Metionin">Metionin</a></li> <li><b>N</b>: <a href="/wiki/Asparagin" title="Asparagin">Asparagin</a></li> <li><b>P</b>: <a href="/wiki/Prolin" title="Prolin">Prolin</a></li> <li><b>Q</b>: <a href="/wiki/Glutamin" title="Glutamin">Glutamin</a></li> <li><b>R</b>: <a href="/wiki/Arginin" title="Arginin">Arginin</a></li> <li><b>S</b>: <a href="/wiki/Serin" title="Serin">Serin</a></li> <li><b>T</b>: <a href="/wiki/Treonin" title="Treonin">Treonin</a></li> <li><b>V</b>: <a href="/wiki/Valin" class="mw-redirect" title="Valin">Valin</a></li> <li><b>W</b>: <a href="/wiki/Triptofan" title="Triptofan">Triptofan</a></li> </small><li><small><b>Y</b>: <a href="/wiki/Tirozin" title="Tirozin">Tirozin</a></small></li></ul> </div> <table style="font-family:monospace;"> <tbody><tr style="text-align:right;"><th>10</th><th></th><th>20</th><th></th><th>30</th><th></th><th>40</th><th></th><th>50</th></tr> <tr style="background-color: #eee;"><td>MEQTVLVPPG</td><td style="background-color: #f9f9f9;"></td><td>PDSFNFFTRE</td><td style="background-color: #f9f9f9;"></td><td>SLAAIERRIA</td><td style="background-color: #f9f9f9;"></td><td>EEKAKNPKPD</td><td style="background-color: #f9f9f9;"></td><td>KKDDDENGPK</td></tr> <tr style="background-color: #eee;"><td>PNSDLEAGKN</td><td style="background-color: #f9f9f9;"></td><td>LPFIYGDIPP</td><td style="background-color: #f9f9f9;"></td><td>EMVSEPLEDL</td><td style="background-color: #f9f9f9;"></td><td>DPYYINKKTF</td><td style="background-color: #f9f9f9;"></td><td>IVLNKGKAIF</td></tr> <tr style="background-color: #eee;"><td>RFSATSALYI</td><td style="background-color: #f9f9f9;"></td><td>LTPFNPLRKI</td><td style="background-color: #f9f9f9;"></td><td>AIKILVHSLF</td><td style="background-color: #f9f9f9;"></td><td>SMLIMCTILT</td><td style="background-color: #f9f9f9;"></td><td>NCVFMTMSNP</td></tr> <tr style="background-color: #eee;"><td>PDWTKNVEYT</td><td style="background-color: #f9f9f9;"></td><td>FTGIYTFESL</td><td style="background-color: #f9f9f9;"></td><td>IKIIARGFCL</td><td style="background-color: #f9f9f9;"></td><td>EDFTFLRDPW</td><td style="background-color: #f9f9f9;"></td><td>NWLDFTVITF</td></tr> <tr style="background-color: #eee;"><td>AYVTEFVDLG</td><td style="background-color: #f9f9f9;"></td><td>NVSALRTFRV</td><td style="background-color: #f9f9f9;"></td><td>LRALKTISVI</td><td style="background-color: #f9f9f9;"></td><td>PGLKTIVGAL</td><td style="background-color: #f9f9f9;"></td><td>IQSVKKLSDV</td></tr> <tr style="background-color: #eee;"><td>MILTVFCLSV</td><td style="background-color: #f9f9f9;"></td><td>FALIGLQLFM</td><td style="background-color: #f9f9f9;"></td><td>GNLRNKCIQW</td><td style="background-color: #f9f9f9;"></td><td>PPTNASLEEH</td><td style="background-color: #f9f9f9;"></td><td>SIEKNITVNY</td></tr> <tr style="background-color: #eee;"><td>NGTLINETVF</td><td style="background-color: #f9f9f9;"></td><td>EFDWKSYIQD</td><td style="background-color: #f9f9f9;"></td><td>SRYHYFLEGF</td><td style="background-color: #f9f9f9;"></td><td>LDALLCGNSS</td><td style="background-color: #f9f9f9;"></td><td>DAGQCPEGYM</td></tr> <tr style="background-color: #eee;"><td>CVKAGRNPNY</td><td style="background-color: #f9f9f9;"></td><td>GYTSFDTFSW</td><td style="background-color: #f9f9f9;"></td><td>AFLSLFRLMT</td><td style="background-color: #f9f9f9;"></td><td>QDFWENLYQL</td><td style="background-color: #f9f9f9;"></td><td>TLRAAGKTYM</td></tr> <tr style="background-color: #eee;"><td>IFFVLVIFLG</td><td style="background-color: #f9f9f9;"></td><td>SFYLINLILA</td><td style="background-color: #f9f9f9;"></td><td>VVAMAYEEQN</td><td style="background-color: #f9f9f9;"></td><td>QATLEEAEQK</td><td style="background-color: #f9f9f9;"></td><td>EAEFQQMIEQ</td></tr> <tr style="background-color: #eee;"><td>LKKQQEAAQQ</td><td style="background-color: #f9f9f9;"></td><td>AATATASEHS</td><td style="background-color: #f9f9f9;"></td><td>REPSAAGRLS</td><td style="background-color: #f9f9f9;"></td><td>DSSSEASKLS</td><td style="background-color: #f9f9f9;"></td><td>SKSAKERRNR</td></tr> <tr style="background-color: #eee;"><td>RKKRKQKEQS</td><td style="background-color: #f9f9f9;"></td><td>GGEEKDEDEF</td><td style="background-color: #f9f9f9;"></td><td>QKSESEDSIR</td><td style="background-color: #f9f9f9;"></td><td>RKGFRFSIEG</td><td style="background-color: #f9f9f9;"></td><td>NRLTYEKRYS</td></tr> <tr style="background-color: #eee;"><td>SPHQSLLSIR</td><td style="background-color: #f9f9f9;"></td><td>GSLFSPRRNS</td><td style="background-color: #f9f9f9;"></td><td>RTSLFSFRGR</td><td style="background-color: #f9f9f9;"></td><td>AKDVGSENDF</td><td style="background-color: #f9f9f9;"></td><td>ADDEHSTFED</td></tr> <tr style="background-color: #eee;"><td>NESRRDSLFV</td><td style="background-color: #f9f9f9;"></td><td>PRRHGERRNS</td><td style="background-color: #f9f9f9;"></td><td>NLSQTSRSSR</td><td style="background-color: #f9f9f9;"></td><td>MLAVFPANGK</td><td style="background-color: #f9f9f9;"></td><td>MHSTVDCNGV</td></tr> <tr style="background-color: #eee;"><td>VSLVGGPSVP</td><td style="background-color: #f9f9f9;"></td><td>TSPVGQLLPE</td><td style="background-color: #f9f9f9;"></td><td>VIIDKPATDD</td><td style="background-color: #f9f9f9;"></td><td>NGTTTETEMR</td><td style="background-color: #f9f9f9;"></td><td>KRRSSSFHVS</td></tr> <tr style="background-color: #eee;"><td>MDFLEDPSQR</td><td style="background-color: #f9f9f9;"></td><td>QRAMSIASIL</td><td style="background-color: #f9f9f9;"></td><td>TNTVEELEES</td><td style="background-color: #f9f9f9;"></td><td>RQKCPPCWYK</td><td style="background-color: #f9f9f9;"></td><td>FSNIFLIWDC</td></tr> <tr style="background-color: #eee;"><td>SPYWLKVKHV</td><td style="background-color: #f9f9f9;"></td><td>VNLVVMDPFV</td><td style="background-color: #f9f9f9;"></td><td>DLAITICIVL</td><td style="background-color: #f9f9f9;"></td><td>NTLFMAMEHY</td><td style="background-color: #f9f9f9;"></td><td>PMTDHFNNVL</td></tr> <tr style="background-color: #eee;"><td>TVGNLVFTGI</td><td style="background-color: #f9f9f9;"></td><td>FTAEMFLKII</td><td style="background-color: #f9f9f9;"></td><td>AMDPYYYFQE</td><td style="background-color: #f9f9f9;"></td><td>GWNIFDGFIV</td><td style="background-color: #f9f9f9;"></td><td>TLSLVELGLA</td></tr> <tr style="background-color: #eee;"><td>NVEGLSVLRS</td><td style="background-color: #f9f9f9;"></td><td>FRLLRVFKLA</td><td style="background-color: #f9f9f9;"></td><td>KSWPTLNMLI</td><td style="background-color: #f9f9f9;"></td><td>KIIGNSVGAL</td><td style="background-color: #f9f9f9;"></td><td>GNLTLVLAII</td></tr> <tr style="background-color: #eee;"><td>VFIFAVVGMQ</td><td style="background-color: #f9f9f9;"></td><td>LFGKSYKDCV</td><td style="background-color: #f9f9f9;"></td><td>CKIASDCQLP</td><td style="background-color: #f9f9f9;"></td><td>RWHMNDFFHS</td><td style="background-color: #f9f9f9;"></td><td>FLIVFRVLCG</td></tr> <tr style="background-color: #eee;"><td>EWIETMWDCM</td><td style="background-color: #f9f9f9;"></td><td>EVAGQAMCLT</td><td style="background-color: #f9f9f9;"></td><td>VFMMVMVIGN</td><td style="background-color: #f9f9f9;"></td><td>LVVLNLFLAL</td><td style="background-color: #f9f9f9;"></td><td>LLSSFSADNL</td></tr> <tr style="background-color: #eee;"><td>AATDDDNEMN</td><td style="background-color: #f9f9f9;"></td><td>NLQIAVDRMH</td><td style="background-color: #f9f9f9;"></td><td>KGVAYVKRKI</td><td style="background-color: #f9f9f9;"></td><td>YEFIQQSFIR</td><td style="background-color: #f9f9f9;"></td><td>KQKILDEIKP</td></tr> <tr style="background-color: #eee;"><td>LDDLNNKKDS</td><td style="background-color: #f9f9f9;"></td><td>CMSNHTAEIG</td><td style="background-color: #f9f9f9;"></td><td>KDLDYLKDVN</td><td style="background-color: #f9f9f9;"></td><td>GTTSGIGTGS</td><td style="background-color: #f9f9f9;"></td><td>SVEKYIIDES</td></tr> <tr style="background-color: #eee;"><td>DYMSFINNPS</td><td style="background-color: #f9f9f9;"></td><td>LTVTVPIAVG</td><td style="background-color: #f9f9f9;"></td><td>ESDFENLNTE</td><td style="background-color: #f9f9f9;"></td><td>DFSSESDLEE</td><td style="background-color: #f9f9f9;"></td><td>SKEKLNESSS</td></tr> <tr style="background-color: #eee;"><td>SSEGSTVDIG</td><td style="background-color: #f9f9f9;"></td><td>APVEEQPVVE</td><td style="background-color: #f9f9f9;"></td><td>PEETLEPEAC</td><td style="background-color: #f9f9f9;"></td><td>FTEGCVQRFK</td><td style="background-color: #f9f9f9;"></td><td>CCQINVEEGR</td></tr> <tr style="background-color: #eee;"><td>GKQWWNLRRT</td><td style="background-color: #f9f9f9;"></td><td>CFRIVEHNWF</td><td style="background-color: #f9f9f9;"></td><td>ETFIVFMILL</td><td style="background-color: #f9f9f9;"></td><td>SSGALAFEDI</td><td style="background-color: #f9f9f9;"></td><td>YIDQRKTIKT</td></tr> <tr style="background-color: #eee;"><td>MLEYADKVFT</td><td style="background-color: #f9f9f9;"></td><td>YIFILEMLLK</td><td style="background-color: #f9f9f9;"></td><td>WVAYGYQTYF</td><td style="background-color: #f9f9f9;"></td><td>TNAWCWLDFL</td><td style="background-color: #f9f9f9;"></td><td>IVDVSLVSLT</td></tr> <tr style="background-color: #eee;"><td>ANALGYSELG</td><td style="background-color: #f9f9f9;"></td><td>AIKSLRTLRA</td><td style="background-color: #f9f9f9;"></td><td>LRPLRALSRF</td><td style="background-color: #f9f9f9;"></td><td>EGMRVVVNAL</td><td style="background-color: #f9f9f9;"></td><td>LGAIPSIMNV</td></tr> <tr style="background-color: #eee;"><td>LLVCLIFWLI</td><td style="background-color: #f9f9f9;"></td><td>FSIMGVNLFA</td><td style="background-color: #f9f9f9;"></td><td>GKFYHCINTT</td><td style="background-color: #f9f9f9;"></td><td>TGDRFDIEDV</td><td style="background-color: #f9f9f9;"></td><td>NNHTDCLKLI</td></tr> <tr style="background-color: #eee;"><td>ERNETARWKN</td><td style="background-color: #f9f9f9;"></td><td>VKVNFDNVGF</td><td style="background-color: #f9f9f9;"></td><td>GYLSLLQVAT</td><td style="background-color: #f9f9f9;"></td><td>FKGWMDIMYA</td><td style="background-color: #f9f9f9;"></td><td>AVDSRNVELQ</td></tr> <tr style="background-color: #eee;"><td>PKYEESLYMY</td><td style="background-color: #f9f9f9;"></td><td>LYFVIFIIFG</td><td style="background-color: #f9f9f9;"></td><td>SFFTLNLFIG</td><td style="background-color: #f9f9f9;"></td><td>VIIDNFNQQK</td><td style="background-color: #f9f9f9;"></td><td>KKFGGQDIFM</td></tr> <tr style="background-color: #eee;"><td>TEEQKKYYNA</td><td style="background-color: #f9f9f9;"></td><td>MKKLGSKKPQ</td><td style="background-color: #f9f9f9;"></td><td>KPIPRPGNKF</td><td style="background-color: #f9f9f9;"></td><td>QGMVFDFVTR</td><td style="background-color: #f9f9f9;"></td><td>QVFDISIMIL</td></tr> <tr style="background-color: #eee;"><td>ICLNMVTMMV</td><td style="background-color: #f9f9f9;"></td><td>ETDDQSEYVT</td><td style="background-color: #f9f9f9;"></td><td>TILSRINLVF</td><td style="background-color: #f9f9f9;"></td><td>IVLFTGECVL</td><td style="background-color: #f9f9f9;"></td><td>KLISLRHYYF</td></tr> <tr style="background-color: #eee;"><td>TIGWNIFDFV</td><td style="background-color: #f9f9f9;"></td><td>VVILSIVGMF</td><td style="background-color: #f9f9f9;"></td><td>LAELIEKYFV</td><td style="background-color: #f9f9f9;"></td><td>SPTLFRVIRL</td><td style="background-color: #f9f9f9;"></td><td>ARIGRILRLI</td></tr> <tr style="background-color: #eee;"><td>KGAKGIRTLL</td><td style="background-color: #f9f9f9;"></td><td>FALMMSLPAL</td><td style="background-color: #f9f9f9;"></td><td>FNIGLLLFLV</td><td style="background-color: #f9f9f9;"></td><td>MFIYAIFGMS</td><td style="background-color: #f9f9f9;"></td><td>NFAYVKREVG</td></tr> <tr style="background-color: #eee;"><td>IDDMFNFETF</td><td style="background-color: #f9f9f9;"></td><td>GNSMICLFQI</td><td style="background-color: #f9f9f9;"></td><td>TTSAGWDGLL</td><td style="background-color: #f9f9f9;"></td><td>APILNSKPPD</td><td style="background-color: #f9f9f9;"></td><td>CDPNKVNPGS</td></tr> <tr style="background-color: #eee;"><td>SVKGDCGNPS</td><td style="background-color: #f9f9f9;"></td><td>VGIFFFVSYI</td><td style="background-color: #f9f9f9;"></td><td>IISFLVVVNM</td><td style="background-color: #f9f9f9;"></td><td>YIAVILENFS</td><td style="background-color: #f9f9f9;"></td><td>VATEESAEPL</td></tr> <tr style="background-color: #eee;"><td>SEDDFEMFYE</td><td style="background-color: #f9f9f9;"></td><td>VWEKFDPDAT</td><td style="background-color: #f9f9f9;"></td><td>QFMEFEKLSQ</td><td style="background-color: #f9f9f9;"></td><td>FAAALEPPLN</td><td style="background-color: #f9f9f9;"></td><td>LPQPNKLQLI</td></tr> <tr style="background-color: #eee;"><td>AMDLPMVSGD</td><td style="background-color: #f9f9f9;"></td><td>RIHCLDILFA</td><td style="background-color: #f9f9f9;"></td><td>FTKRVLGESG</td><td style="background-color: #f9f9f9;"></td><td>EMDALRIQME</td><td style="background-color: #f9f9f9;"></td><td>ERFMASNPSK</td></tr> <tr style="background-color: #eee;"><td>VSYQPITTTL</td><td style="background-color: #f9f9f9;"></td><td>KRKQEEVSAV</td><td style="background-color: #f9f9f9;"></td><td>IIQRAYRRHL</td><td style="background-color: #f9f9f9;"></td><td>LKRTVKQASF</td><td style="background-color: #f9f9f9;"></td><td>TYNKNKIKGG</td></tr> <tr style="background-color: #eee;"><td>ANLLIKEDMI</td><td style="background-color: #f9f9f9;"></td><td>IDRINENSIT</td><td style="background-color: #f9f9f9;"></td><td>EKTDLTMSTA</td><td style="background-color: #f9f9f9;"></td><td>ACPPSYDRVT</td><td style="background-color: #f9f9f9;"></td><td>KPIVEKHEQE</td></tr> <tr style="background-color: #eee;"><td>GKDEKAKGK</td></tr> </tbody></table> <div class="mw-heading mw-heading2"><h2 id="Funkcija">Funkcija</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SCN1A&veaction=edit&section=3" title="Uredi odlomak "Funkcija"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=SCN1A&action=edit&section=3" title="Edit section's source code: Funkcija"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Ki%C4%8Dmenjaci" title="Kičmenjaci">Kičmenjački</a> <a href="/wiki/Natrijski_kanal" title="Natrijski kanal">natrijski kanal</a> je <a href="/w/index.php?title=Naponski-ovisni_ionki_kanal&action=edit&redlink=1" class="new" title="Naponski-ovisni ionki kanal (stranica ne postoji)">naponski-ovisni ionki kanal</a>, neophodan za stvaranje i širenje <a href="/wiki/Akcijski_potencijal" title="Akcijski potencijal">akcijskih potencijala</a>, uglavnom u nervima i <a href="/wiki/Mi%C5%A1i%C4%87" title="Mišić">mišićima</a>. Natrijski kanali osetljivi na napon su heteromerni kompleksi koji se sastoje od velike centralne glikozilovane alfa podjedinice koja stvara pore i dvije manje pomoćne beta podjedinice. Funkcionalne studije su pokazale da je transmembranska alfa podjedinica moždanih natrijevih kanala dovoljna za ekspresiju funkcionalnih natrijevih kanala.<sup id="cite_ref-pmid2429308_13-0" class="reference"><a href="#cite_note-pmid2429308-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> Alfa podjedinice moždanih natrijskih kanala mozga formiraju potporodicu gena sa nekoliko strukturno različitih <a href="/wiki/Izoforma" class="mw-redirect" title="Izoforma">izoformi</a> grupisanih na hromosomskoj ref+giji 2q24, tipovi I, II (<a href="/w/index.php?title=Nav1.2&action=edit&redlink=1" class="new" title="Nav1.2 (stranica ne postoji)">Na<sub>v</sub>1.2</a>) i III (<a href="/w/index.php?title=SCN3A&action=edit&redlink=1" class="new" title="SCN3A (stranica ne postoji)">Na<sub>v</sub>1.3</a>). Također postoji nekoliko različitih izoformi alfa podjedinica natrijevih kanala u skeletnim i srčanim mišićima (<a href="/w/index.php?title=Nav1.4&action=edit&redlink=1" class="new" title="Nav1.4 (stranica ne postoji)">Na<sub>v</sub>1.4</a><sup id="cite_ref-pmid1315496_14-0" class="reference"><a href="#cite_note-pmid1315496-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> i <a href="/w/index.php?title=Nav1.5&action=edit&redlink=1" class="new" title="Nav1.5 (stranica ne postoji)">Na<sub>v</sub>1.5</a>).<sup id="cite_ref-pmid1309946_15-0" class="reference"><a href="#cite_note-pmid1309946-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> </p><p>SCN1A gen kodira <a href="/w/index.php?title=G_protein&action=edit&redlink=1" class="new" title="G protein (stranica ne postoji)">alfa podjedinicu</a> napo-ovisnog natrijevog ionskog kanala, što ga čini članom deset <a href="/w/index.php?title=Homologija_sekv_ence&action=edit&redlink=1" class="new" title="Homologija sekv ence (stranica ne postoji)">paralognih</a> porodica gena koje kodiraju <a href="/w/index.php?title=Naponski-ovisni_natrijski_kanal&action=edit&redlink=1" class="new" title="Naponski-ovisni natrijski kanal (stranica ne postoji)">naponski natrijev</a> <a href="/wiki/Transmembranski_protein" title="Transmembranski protein">transmembranski protein</a> Na<sub>V</sub>1.1. Unutar porodice gena koji kodiraju druge dijelove naponski-oviksnihnatrijskih kanala, mutacije SCN1A su prve identificirane, jer su mutacije ovog gena uzrokovale <a href="/wiki/Epilepsija" title="Epilepsija">epilepsiju</a> i febrilne <a href="/wiki/Epilepsijski_napad" class="mw-redirect" title="Epilepsijski napad">napade</a>.<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> Odista, gen SCN1A je jedan od najčešće mutiranih gena u ljudskom <a href="/wiki/Genom" title="Genom">genomu</a> koji je povezan s epilepsijom, što mu je dalo titulu „gena super krivca“.<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> Postoji 900 različitih <a href="/wiki/Mutacija" title="Mutacija">mutacija</a> prijavljenih za gen SCN1A, otprilike polovina prijavljenih mutacija su skraćivanja koja rezultiraju bez sinteze proteina.<sup id="cite_ref-:3_18-0" class="reference"><a href="#cite_note-:3-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> Preostala polovina mutacija su <a href="/wiki/Misens_mutacija" title="Misens mutacija">misens mutacije</a>, za koje se predviđa da će ili uzrokovati <a href="/w/index.php?title=Amorf&action=edit&redlink=1" class="new" title="Amorf (stranica ne postoji)">gubitsk funkcije</a> ili <a href="/w/index.php?title=Hipermorf&action=edit&redlink=1" class="new" title="Hipermorf (stranica ne postoji)">dobitak funkcija</a>, iako je vrlo malo njih testirano na funkcionalnost u laboratoriji.<sup id="cite_ref-:0_9-1" class="reference"><a href="#cite_note-:0-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p><p>Suptilne razlike u naponskim kanalima natrijevih iona, mogu imati razorne fiziološke efekte i biti u osnovi abnormalnog neurološkog funkcionisanja.<sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> Mutations to the SCN1A gene most often result in different forms of seizure disorders, the most common forms of seizure disorders are Dravet Syndrome (DS), Intractable childhood epilepsy with generalized tonic-clonic seizures (ICEGTC), and severe myoclonic epilepsy borderline (SMEB).<sup id="cite_ref-:3_18-1" class="reference"><a href="#cite_note-:3-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> Klinički, 70-80% pacijenata sa DS je identifikovano s mutacijama specifičnim za gen SCN1A, koje su uzrokovane <i><a href="/wiki/De_novo" title="De novo">de novo</a></i> <a href="/wiki/Heterozigot" title="Heterozigot">heterozigotnim</a> mutacijama gena SCN1A.<sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> Do sada postoje dvije <a href="/wiki/Baze_podataka" class="mw-redirect" title="Baze podataka">baze podataka</a> o SCN1A mutacijama, <a rel="nofollow" class="external text" href="http://www/scn1a.info/">Infobase</a> i <a rel="nofollow" class="external text" href="http://www.molgen.ua.ac.be/SCN1AMutations/">SCN1A varijantna baza podataka</a> <a rel="nofollow" class="external text" href="https://web.archive.org/web/20190722223010/http://www.molgen.ua.ac.be/SCN1AMutations/">Arhivirano</a> 22. 7. 2019. na <a href="/wiki/Wayback_Machine" title="Wayback Machine">Wayback Machine</a>. </p><p>Miševi s <a href="/wiki/Nokaut-mi%C5%A1" title="Nokaut-miš">nok-in</a> SCN1A mutacijama, koji su <a href="/wiki/Modelni_organizmi" class="mw-redirect" title="Modelni organizmi">modelni organizmi</a> za DS, brzo razvijaju napade, što ukazuje na značajno smanjenje funkcije Na<sub>V</sub>1.1.<sup id="cite_ref-:1_10-1" class="reference"><a href="#cite_note-:1-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> Pretpostavljeno je da smanjene struje natrija zbog Na<sub>V</sub>1.1 mutacija mogu uzrokovati hipoekscitabilnost u <a href="/w/index.php?title=GABAA-receptor&action=edit&redlink=1" class="new" title="GABAA-receptor (stranica ne postoji)">GABA inhibitornim interneuronima</a>, što dovodi do <a href="/wiki/Epilepsija" title="Epilepsija">epilepsije</a>.<sup id="cite_ref-:2_12-1" class="reference"><a href="#cite_note-:2-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> Miševi i u <a href="/wiki/Homozigot" title="Homozigot">homozigotnom</a> i u <a href="/wiki/Heterozigot" title="Heterozigot">heterozigotnolm</a> stanju razvijaju <a href="/wiki/Fenotip" title="Fenotip">fenotip</a> <a href="/wiki/Epilepsijski_napad" class="mw-redirect" title="Epilepsijski napad">napada</a> i ataksiju. Iako homozigotni miševi umiru u prosjeku tokom druge do treće sedmice života, a otprilike 50% heterozigotnih nul-miševa preživi u odrasloj dobi.<sup id="cite_ref-:1_10-2" class="reference"><a href="#cite_note-:1-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-:2_12-2" class="reference"><a href="#cite_note-:2-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Klinički_značaj"><span id="Klini.C4.8Dki_zna.C4.8Daj"></span>Klinički značaj</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SCN1A&veaction=edit&section=4" title="Uredi odlomak "Klinički značaj"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=SCN1A&action=edit&section=4" title="Edit section's source code: Klinički značaj"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Mutacije u genu SCN1A uzrokuju nasljedne <a href="/w/index.php?title=Febrilni_napad&action=edit&redlink=1" class="new" title="Febrilni napad (stranica ne postoji)">febrilne napade</a> i <a href="/w/index.php?title=Generalizirana_epilepsija_s_febrilnim_napadima_plus&action=edit&redlink=1" class="new" title="Generalizirana epilepsija s febrilnim napadima plus (stranica ne postoji)">GEFS+, tip 2</a>.<sup id="cite_ref-pmid10742094_24-0" class="reference"><a href="#cite_note-pmid10742094-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid11567038_25-0" class="reference"><a href="#cite_note-pmid11567038-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid12821740_26-0" class="reference"><a href="#cite_note-pmid12821740-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-urlwww.scn1a.info_–_SCN1A_infobase_27-0" class="reference"><a href="#cite_note-urlwww.scn1a.info_–_SCN1A_infobase-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Interakcije">Interakcije</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SCN1A&veaction=edit&section=5" title="Uredi odlomak "Interakcije"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=SCN1A&action=edit&section=5" title="Edit section's source code: Interakcije"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Pokazalo se da Na<sub>v</sub>1.1 ima <a href="/wiki/Interakcija_protein-protein" title="Interakcija protein-protein">reakcije</a> sa <a href="/w/index.php?title=Sintropin_alfa_1&action=edit&redlink=1" class="new" title="Sintropin alfa 1 (stranica ne postoji)">sintropinom alfa 1</a>.<sup id="cite_ref-pmid9412493_28-0" class="reference"><a href="#cite_note-pmid9412493-28"><span class="cite-bracket">[</span>28<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Također_pogledajte"><span id="Tako.C4.91er_pogledajte"></span>Također pogledajte</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SCN1A&veaction=edit&section=6" title="Uredi odlomak "Također pogledajte"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=SCN1A&action=edit&section=6" title="Edit section's source code: Također pogledajte"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Natrijski_kanal" title="Natrijski kanal">Natrijski kanal</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Reference">Reference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SCN1A&veaction=edit&section=7" title="Uredi odlomak "Reference"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=SCN1A&action=edit&section=7" title="Edit section's source code: Reference"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r3312388">.mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-refGRCh38Ensembl-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCh38Ensembl_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000144285">GRCh38: Ensembl release 89: ENSG00000144285</a> - <a href="/wiki/Ensembl_projekt_genomskih_podataka" title="Ensembl projekt genomskih podataka">Ensembl</a>, maj 2017</span> </li> <li id="cite_note-refGRCm38Ensembl-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCm38Ensembl_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Mus_musculus/Gene/Summary?db=core;g=ENSMUSG00000064329">GRCm38: Ensembl release 89: ENSMUSG00000064329</a> - <a href="/wiki/Ensembl_projekt_genomskih_podataka" title="Ensembl projekt genomskih podataka">Ensembl</a>, maj 2017</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a 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a{background:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-ws-icon a{background:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-maint{display:none;color:#33aa33;margin-left:0.3em}.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output 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title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Primary+structure+and+functional+expression+of+the+human+cardiac+tetrodotoxin-insensitive+voltage-dependent+sodium+channel&rft.volume=89&rft.issue=2&rft.pages=554-8&rft.date=1992-01&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC48277%23id-name%3DPMC&rft_id=info%3Apmid%2F1309946&rft_id=info%3Adoi%2F10.1073%2Fpnas.89.2.554&rft_id=info%3Abibcode%2F1992PNAS...89..554G&rft.aulast=Gellens&rft.aufirst=ME&rft.au=George%2C+AL&rft.au=Chen%2C+LQ&rft.au=Chahine%2C+M&rft.au=Horn%2C+R&rft.au=Barchi%2C+RL&rft.au=Kallen%2C+RG&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC48277&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ASCN1A" class="Z3988"></span></span> </li> <li id="cite_note-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-16">^</a></b></span> <span class="reference-text">Escayg, 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Pristupljeno 30. 10. 2009</span>. <q>compilation of genetic variations in the SCN1A gene that alter the expression or function of Nav1.1</q></cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=SCN1A+infobase&rft.au=Lossin+C&rft_id=http%3A%2F%2Fwww.scn1a.info%2F&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ASCN1A" class="Z3988"></span></span> </li> <li id="cite_note-pmid9412493-28"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid9412493_28-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFGeeMadhavanLevinsonCaldwell1998" class="citation journal cs1">Gee SH, Madhavan R, Levinson SR, Caldwell JH, Sealock R, Froehner SC (januar 1998). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC6793384">"Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins"</a>. <i>The Journal of Neuroscience</i>. <b>18</b> (1): 128–37. <a href="/wiki/Doi_(identifikator)" class="mw-redirect" title="Doi (identifikator)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1523%2Fjneurosci.18-01-00128.1998">10.1523/jneurosci.18-01-00128.1998</a>. <a href="/wiki/PMC_(identifikator)" class="mw-redirect" title="PMC (identifikator)">PMC</a> <span class="cs1-lock-free" title="Slobodno dostupno"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC6793384">6793384</a></span>. <a href="/wiki/PMID_(identifikator)" class="mw-redirect" title="PMID (identifikator)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/9412493">9412493</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Neuroscience&rft.atitle=Interaction+of+muscle+and+brain+sodium+channels+with+multiple+members+of+the+syntrophin+family+of+dystrophin-associated+proteins&rft.volume=18&rft.issue=1&rft.pages=128-37&rft.date=1998-01&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6793384%23id-name%3DPMC&rft_id=info%3Apmid%2F9412493&rft_id=info%3Adoi%2F10.1523%2Fjneurosci.18-01-00128.1998&rft.aulast=Gee&rft.aufirst=SH&rft.au=Madhavan%2C+R&rft.au=Levinson%2C+SR&rft.au=Caldwell%2C+JH&rft.au=Sealock%2C+R&rft.au=Froehner%2C+SC&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6793384&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ASCN1A" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Dopunska_literatura">Dopunska literatura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SCN1A&veaction=edit&section=8" title="Uredi odlomak "Dopunska literatura"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=SCN1A&action=edit&section=8" title="Edit section's source code: Dopunska literatura"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r3303351">.mw-parser-output .refbegin{font-size:90%;margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-100{font-size:100%}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}</style><div class="refbegin refbegin-columns references-column-width" style="column-width: 33em"> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFLercheJurkat-RottLehmann-Horn2001" class="citation journal cs1">Lerche H, Jurkat-Rott K, Lehmann-Horn F (2001). 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title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Epilepsy+Research&rft.atitle=Autosomal+dominant+epilepsy+with+febrile+seizures+plus+with+missense+mutations+of+the+%28Na%2B%29-channel+alpha+1+subunit+gene%2C+SCN1A&rft.volume=48&rft.issue=1%E2%80%932&rft.pages=15-23&rft.date=2002-01&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A25555020%23id-name%3DS2CID&rft_id=info%3Apmid%2F11823106&rft_id=info%3Adoi%2F10.1016%2FS0920-1211%2801%2900313-8&rft.aulast=Ito&rft.aufirst=M&rft.au=Nagafuji%2C+H&rft.au=Okazawa%2C+H&rft.au=Yamakawa%2C+K&rft.au=Sugawara%2C+T&rft.au=Mazaki-Miyazaki%2C+E&rft.au=Hirose%2C+S&rft.au=Fukuma%2C+G&rft.au=Mitsudome%2C+A&rft.au=Wada%2C+K&rft.au=Kaneko%2C+S&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ASCN1A" class="Z3988"></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="Vanjski_linkovi">Vanjski linkovi</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SCN1A&veaction=edit&section=9" title="Uredi odlomak "Vanjski linkovi"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=SCN1A&action=edit&section=9" title="Edit section's source code: Vanjski linkovi"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/books/NBK1388/">GeneReviews/NCBI/NIH/UW entry on Familial Hemiplegic Migraine</a></li> <li><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=gefs">GeneReviews/NCBI/NIH/UW entry on SCN1A-Related Seizure Disorders</a></li> <li><a rel="nofollow" class="external text" href="//www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?mode=&term=SCN1A+protein,+human">SCN1A protein, human</a> na <i>US National Library of Medicine</i> <a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">Medical Subject Headings</a> (MeSH)</li></ul> <div role="navigation" class="navbox" aria-labelledby="PDB_galerija" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><style data-mw-deduplicate="TemplateStyles:r3312386">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}.mw-parser-output .infobox .navbar{font-size:100%}.mw-parser-output .navbox .navbar{display:block;font-size:100%}.mw-parser-output .navbox-title .navbar{float:left;text-align:left;margin-right:0.5em}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-pogledaj"><a href="/wiki/%C5%A0ablon:PDB_Galerija" title="Šablon:PDB Galerija"><abbr title="Pogledaj šablon" style=";;background:none transparent;border:none;box-shadow:none;padding:0;">p</abbr></a></li><li class="nv-razgovor"><a href="/w/index.php?title=Razgovor_o_%C5%A1ablonu:PDB_Galerija&action=edit&redlink=1" class="new" title="Razgovor o šablonu:PDB Galerija (stranica ne postoji)"><abbr title="Razgovor o šablonu" style=";;background:none transparent;border:none;box-shadow:none;padding:0;">r</abbr></a></li><li class="nv-uredi"><a class="external text" href="https://bs.wikipedia.org/w/index.php?title=%C5%A0ablon:PDB_Galerija&action=edit"><abbr title="Uredi šablon" style=";;background:none transparent;border:none;box-shadow:none;padding:0;">u</abbr></a></li></ul></div><div id="PDB_galerija" style="font-size:114%;margin:0 4em">PDB galerija</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=%C5%A0ablon:PDB_Gallery/6323&action=edit&redlink=1" class="new" title="Šablon:PDB Gallery/6323 (stranica ne postoji)">Šablon:PDB Gallery/6323</a></div></td></tr></tbody></table></div> <div role="navigation" class="navbox" aria-labelledby="Protein_membranskog_transporta:_ionski_kanali_(TC_1A)" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3312386"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-pogledaj"><a href="/wiki/%C5%A0ablon:Navbox_with_collapsible_groups" title="Šablon:Navbox with collapsible groups"><abbr title="Pogledaj šablon" style=";;background:none transparent;border:none;box-shadow:none;padding:0;">p</abbr></a></li><li class="nv-razgovor"><a href="/w/index.php?title=Razgovor_o_%C5%A1ablonu:Navbox_with_collapsible_groups&action=edit&redlink=1" class="new" title="Razgovor o šablonu:Navbox with collapsible groups (stranica ne postoji)"><abbr title="Razgovor o šablonu" style=";;background:none transparent;border:none;box-shadow:none;padding:0;">r</abbr></a></li><li class="nv-uredi"><a class="external text" href="https://bs.wikipedia.org/w/index.php?title=%C5%A0ablon:Navbox_with_collapsible_groups&action=edit"><abbr title="Uredi šablon" style=";;background:none transparent;border:none;box-shadow:none;padding:0;">u</abbr></a></li></ul></div><div id="Protein_membranskog_transporta:_ionski_kanali_(TC_1A)" style="font-size:114%;margin:0 4em"><a href="/wiki/Protein_membranskog_transporta" class="mw-redirect" title="Protein membranskog transporta">Protein membranskog transporta</a>: <a href="/wiki/Ionski_kanal" title="Ionski kanal">ionski kanali</a> (<a href="/wiki/Transporter_Classification_Database#1._Channels/Pores" class="mw-redirect" title="Transporter Classification Database">TC 1A</a>)</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks mw-collapsible autocollapse navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style=";"><div id="Ca2+:_Kalcijev_kanal" style="font-size:114%;margin:0 4em"><i>Ca<sup>2+</sup>:</i> <a href="/wiki/Kalcijev_kanal" class="mw-redirect" title="Kalcijev kanal">Kalcijev kanal</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px;width:auto;;background-color: AntiqueWhite;"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Inositol_trisphosphate_receptor&action=edit&redlink=1" class="new" title="Inositol trisphosphate receptor (stranica ne postoji)">Inositol trisphosphate receptor</a> <ul><li><a href="/w/index.php?title=ITPR1&action=edit&redlink=1" class="new" title="ITPR1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=ITPR2&action=edit&redlink=1" class="new" title="ITPR2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=ITPR3&action=edit&redlink=1" class="new" title="ITPR3 (stranica ne postoji)">3</a></li></ul></li> <li><a href="/w/index.php?title=Ryanodine_receptor&action=edit&redlink=1" class="new" title="Ryanodine receptor (stranica ne postoji)">Ryanodine receptor</a> <ul><li><a href="/wiki/RYR1" title="RYR1">1</a></li> <li><a href="/w/index.php?title=Ryanodine_receptor_2&action=edit&redlink=1" class="new" title="Ryanodine receptor 2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=RYR3&action=edit&redlink=1" class="new" title="RYR3 (stranica ne postoji)">3</a></li></ul></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0px;width:auto;"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=L-tip_kalcijev_kanal&action=edit&redlink=1" class="new" title="L-tip kalcijev kanal (stranica ne postoji)">L-type</a>/<i>Ca<sub>v</sub>α</i> <ul><li><a href="/wiki/Cav1.1" title="Cav1.1">1.1</a></li> <li><a href="/wiki/Cav1.2" title="Cav1.2">1.2</a></li> <li><a href="/w/index.php?title=Cav1.3&action=edit&redlink=1" class="new" title="Cav1.3 (stranica ne postoji)">1.3</a></li> <li><a href="/wiki/Cav1.4" title="Cav1.4">1.4</a></li></ul></li> <li><a href="/w/index.php?title=N-tip_kalcijev_kanal&action=edit&redlink=1" class="new" title="N-tip kalcijev kanal (stranica ne postoji)">N-type</a>/<i>Ca<sub>v</sub>α2.2</i></li> <li><a href="/w/index.php?title=P-tip_kalcijev_kanal&action=edit&redlink=1" class="new" title="P-tip kalcijev kanal (stranica ne postoji)">P-type</a>/<i>Ca<sub>v</sub>α</i> <ul><li><a href="/wiki/Cav2.1" class="mw-redirect" title="Cav2.1">2.1</a></li></ul></li> <li><a href="/w/index.php?title=Q-tip_kalcijev_kanal&action=edit&redlink=1" class="new" title="Q-tip kalcijev kanal (stranica ne postoji)">Q-type</a>/<i>Ca<sub>v</sub>α2.1</i></li> <li><a href="/w/index.php?title=R-tip_kalcijev_kanal&action=edit&redlink=1" class="new" title="R-tip kalcijev kanal (stranica ne postoji)">R-type</a>/<i>Ca<sub>v</sub>α2.3</i></li> <li><a href="/w/index.php?title=T-tip_kalcijev_kanal&action=edit&redlink=1" class="new" title="T-tip kalcijev kanal (stranica ne postoji)">T-type</a>/<i>Ca<sub>v</sub>α</i> <ul><li><a href="/w/index.php?title=CACNA1G&action=edit&redlink=1" class="new" title="CACNA1G (stranica ne postoji)">3.1</a></li> <li><a href="/w/index.php?title=CACNA1H&action=edit&redlink=1" class="new" title="CACNA1H (stranica ne postoji)">3.2</a></li> <li><a href="/w/index.php?title=CACNA1I&action=edit&redlink=1" class="new" title="CACNA1I (stranica ne postoji)">3.3</a></li></ul></li></ul> <ul><li><i>α<sub>2</sub>δ-subunits</i> <ul><li><a href="/w/index.php?title=CACNA2D1&action=edit&redlink=1" class="new" title="CACNA2D1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=CACNA2D2&action=edit&redlink=1" class="new" title="CACNA2D2 (stranica ne postoji)">2</a></li></ul></li> <li><i>β-subunits</i> <ul><li><a href="/w/index.php?title=CACNB1&action=edit&redlink=1" class="new" title="CACNB1 (stranica ne postoji)">β1</a></li> <li><a href="/wiki/CACNB2" title="CACNB2">β2</a></li> <li><a href="/w/index.php?title=CACNB3&action=edit&redlink=1" class="new" title="CACNB3 (stranica ne postoji)">β3</a></li> <li><a href="/w/index.php?title=CACNB4&action=edit&redlink=1" class="new" title="CACNB4 (stranica ne postoji)">β4</a></li></ul></li> <li><i>γ-subunits</i> <ul><li><a href="/w/index.php?title=CACNG1&action=edit&redlink=1" class="new" title="CACNG1 (stranica ne postoji)">γ1</a></li> <li><a href="/w/index.php?title=CACNG2&action=edit&redlink=1" class="new" title="CACNG2 (stranica ne postoji)">γ2</a></li> <li><a href="/w/index.php?title=CACNG3&action=edit&redlink=1" class="new" title="CACNG3 (stranica ne postoji)">γ3</a></li> <li><a href="/w/index.php?title=CACNG4&action=edit&redlink=1" class="new" title="CACNG4 (stranica ne postoji)">γ4</a></li></ul></li></ul> <ul><li><a href="/w/index.php?title=Cation_channels_of_sperm&action=edit&redlink=1" class="new" title="Cation channels of sperm (stranica ne postoji)">Cation channels of sperm</a> <ul><li><a href="/w/index.php?title=CatSper1&action=edit&redlink=1" class="new" title="CatSper1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=CatSper2&action=edit&redlink=1" class="new" title="CatSper2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=CatSper3&action=edit&redlink=1" class="new" title="CatSper3 (stranica ne postoji)">3</a></li> <li><a href="/w/index.php?title=CatSper4&action=edit&redlink=1" class="new" title="CatSper4 (stranica ne postoji)">4</a></li></ul></li> <li><a href="/w/index.php?title=Two-pore_channel&action=edit&redlink=1" class="new" title="Two-pore channel (stranica ne postoji)">Two-pore channel</a> <ul><li><a href="/w/index.php?title=TPCN1&action=edit&redlink=1" class="new" title="TPCN1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=TPCN2&action=edit&redlink=1" class="new" title="TPCN2 (stranica ne postoji)">2</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks mw-collapsible uncollapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style=";"><div id="Na+:_Natrijev_kanal" style="font-size:114%;margin:0 4em"><i>Na<sup>+</sup>:</i> <a href="/wiki/Natrijev_kanal" class="mw-redirect" title="Natrijev kanal">Natrijev kanal</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px;width:auto;;background-color: AntiqueWhite;"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Epithelial_sodium_channel&action=edit&redlink=1" class="new" title="Epithelial sodium channel (stranica ne postoji)">Epithelial sodium channel</a> <ul><li><a href="/wiki/SCNN1A" title="SCNN1A">α</a></li> <li><a href="/wiki/SCNN1B" title="SCNN1B">β</a></li> <li><a href="/wiki/SCNN1G" title="SCNN1G">γ</a></li> <li><a href="/wiki/SCNN1D" title="SCNN1D">δ</a></li></ul></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0px;width:auto;"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Acid-sensing_ion_channel&action=edit&redlink=1" class="new" title="Acid-sensing ion channel (stranica ne postoji)">Amiloride-sensitive cation channel</a> <ul><li><a href="/w/index.php?title=ACCN1&action=edit&redlink=1" class="new" title="ACCN1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=ACCN2&action=edit&redlink=1" class="new" title="ACCN2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=ACCN3&action=edit&redlink=1" class="new" title="ACCN3 (stranica ne postoji)">3</a></li> <li><a href="/w/index.php?title=ACCN4&action=edit&redlink=1" class="new" title="ACCN4 (stranica ne postoji)">4</a></li></ul></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px;width:auto;;background-color: AntiqueWhite;"><div style="padding:0em 0.25em"> <ul><li><i>Na<sub>v</sub>α</i> <ul><li><a href="/w/index.php?title=Nav1.1&action=edit&redlink=1" class="new" title="Nav1.1 (stranica ne postoji)">1.1</a></li> <li><a href="/w/index.php?title=Nav1.2&action=edit&redlink=1" class="new" title="Nav1.2 (stranica ne postoji)">1.2</a></li> <li><a href="/w/index.php?title=SCN3A&action=edit&redlink=1" class="new" title="SCN3A (stranica ne postoji)">1.3</a></li> <li><a href="/w/index.php?title=Nav1.4&action=edit&redlink=1" class="new" title="Nav1.4 (stranica ne postoji)">1.4</a></li> <li><a href="/w/index.php?title=Nav1.5&action=edit&redlink=1" class="new" title="Nav1.5 (stranica ne postoji)">1.5</a></li> <li><a href="/w/index.php?title=SCN8A&action=edit&redlink=1" class="new" title="SCN8A (stranica ne postoji)">1.6</a></li> <li><a href="/w/index.php?title=Nav1.7&action=edit&redlink=1" class="new" title="Nav1.7 (stranica ne postoji)">1.7</a></li> <li><a href="/w/index.php?title=SCN10A&action=edit&redlink=1" class="new" title="SCN10A (stranica ne postoji)">1.8</a></li> <li><a href="/w/index.php?title=Nav1.9&action=edit&redlink=1" class="new" title="Nav1.9 (stranica ne postoji)">1.9</a></li> <li><a href="/w/index.php?title=SCN7A&action=edit&redlink=1" class="new" title="SCN7A (stranica ne postoji)">7A</a></li></ul></li> <li><i>Na<sub>v</sub>β</i> <ul><li><a href="/wiki/SCN1B" title="SCN1B">1</a></li> <li><a href="/w/index.php?title=SCN2B&action=edit&redlink=1" class="new" title="SCN2B (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=SCN3B&action=edit&redlink=1" class="new" title="SCN3B (stranica ne postoji)">3</a></li> <li><a href="/wiki/SCN4B" title="SCN4B">4</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks mw-collapsible autocollapse navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style=";"><div id="K+:_Kalijev_kanal" style="font-size:114%;margin:0 4em"><i>K<sup>+</sup>:</i> <a href="/wiki/Kalijev_kanal" class="mw-redirect" title="Kalijev kanal">Kalijev kanal</a></div></th></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks mw-collapsible autocollapse navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style=";"><div id="Razno" style="font-size:114%;margin:0 4em"><i>Razno</i></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px;width:auto;;background-color: AntiqueWhite;"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Calcium-activated_chloride_channel&action=edit&redlink=1" class="new" title="Calcium-activated chloride channel (stranica ne postoji)">Calcium-activated chloride channels</a> <ul><li><i>Anoctamin</i> <ul><li><a href="/w/index.php?title=ANO1&action=edit&redlink=1" class="new" title="ANO1 (stranica ne postoji)">ANO1</a></li></ul></li> <li><i>Bestrophin</i> <ul><li><a href="/w/index.php?title=Bestrophin_1&action=edit&redlink=1" class="new" title="Bestrophin 1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=BEST2&action=edit&redlink=1" class="new" title="BEST2 (stranica ne postoji)">2</a></li></ul></li> <li><i>Chloride Channel Accessory</i> <ul><li><a href="/w/index.php?title=CLCA1&action=edit&redlink=1" class="new" title="CLCA1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=CLCA2&action=edit&redlink=1" class="new" title="CLCA2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=CLCA3&action=edit&redlink=1" class="new" title="CLCA3 (stranica ne postoji)">3</a></li> <li><a href="/w/index.php?title=CLCA4&action=edit&redlink=1" class="new" title="CLCA4 (stranica ne postoji)">4</a></li></ul></li></ul></li> <li><a href="/w/index.php?title=Cystic_fibrosis_transmembrane_conductance_regulator&action=edit&redlink=1" class="new" title="Cystic fibrosis transmembrane conductance regulator (stranica ne postoji)">CFTR</a></li> <li><i>CLCN</i> <ul><li><a href="/wiki/CLCN1" title="CLCN1">1</a></li> <li><a href="/w/index.php?title=CLCN2&action=edit&redlink=1" class="new" title="CLCN2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=CLCN3&action=edit&redlink=1" class="new" title="CLCN3 (stranica ne postoji)">3</a></li> <li><a href="/w/index.php?title=CLCN4&action=edit&redlink=1" class="new" title="CLCN4 (stranica ne postoji)">4</a></li> <li><a href="/wiki/CLCN5" title="CLCN5">5</a></li> <li><a href="/w/index.php?title=CLCN6&action=edit&redlink=1" class="new" title="CLCN6 (stranica ne postoji)">6</a></li> <li><a href="/wiki/CLCN7" title="CLCN7">7</a></li> <li><a href="/w/index.php?title=CLCNKA&action=edit&redlink=1" class="new" title="CLCNKA (stranica ne postoji)">KA</a></li> <li><a href="/wiki/CLCNKB" title="CLCNKB">KB</a></li></ul></li> <li><i>CLIC</i> <ul><li><a href="/w/index.php?title=CLIC1&action=edit&redlink=1" class="new" title="CLIC1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=CLIC2&action=edit&redlink=1" class="new" title="CLIC2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=CLIC3&action=edit&redlink=1" class="new" title="CLIC3 (stranica ne postoji)">3</a></li> <li><a href="/wiki/CLIC4" title="CLIC4">4</a></li> <li><a href="/w/index.php?title=CLIC5&action=edit&redlink=1" class="new" title="CLIC5 (stranica ne postoji)">5</a></li> <li><a href="/w/index.php?title=CLIC6&action=edit&redlink=1" class="new" title="CLIC6 (stranica ne postoji)">6</a></li> <li><a href="/w/index.php?title=CLCC1&action=edit&redlink=1" class="new" title="CLCC1 (stranica ne postoji)">L1</a></li></ul></li> <li><i>CLNS</i> <ul><li><a href="/w/index.php?title=CLNS1A&action=edit&redlink=1" class="new" title="CLNS1A (stranica ne postoji)">1A</a></li> <li><a href="/w/index.php?title=CLNS1B&action=edit&redlink=1" class="new" title="CLNS1B (stranica ne postoji)">1B</a></li></ul></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0px;width:auto;"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=HVCN1&action=edit&redlink=1" class="new" title="HVCN1 (stranica ne postoji)">HVCN1</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px;width:auto;;background-color: AntiqueWhite;"><div style="padding:0em 0.25em"> <ul><li><i>α</i> <ul><li><a href="/w/index.php?title=Cyclic_nucleotide-gated_channel_alpha_1&action=edit&redlink=1" class="new" title="Cyclic nucleotide-gated channel alpha 1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=Cyclic_nucleotide-gated_channel_alpha_2&action=edit&redlink=1" class="new" title="Cyclic nucleotide-gated channel alpha 2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=Cyclic_nucleotide-gated_channel_alpha_3&action=edit&redlink=1" class="new" title="Cyclic nucleotide-gated channel alpha 3 (stranica ne postoji)">3</a></li> <li><a href="/w/index.php?title=Cyclic_nucleotide-gated_channel_alpha_4&action=edit&redlink=1" class="new" title="Cyclic nucleotide-gated channel alpha 4 (stranica ne postoji)">4</a></li></ul></li> <li><i>β</i> <ul><li><a href="/w/index.php?title=CNGB1&action=edit&redlink=1" class="new" title="CNGB1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=Cyclic_nucleotide-gated_channel_alpha_4&action=edit&redlink=1" class="new" title="Cyclic nucleotide-gated channel alpha 4 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=Cyclic_nucleotide_gated_channel_beta_3&action=edit&redlink=1" class="new" title="Cyclic nucleotide gated channel beta 3 (stranica ne postoji)">3</a></li></ul></li> <li><i><a href="/w/index.php?title=HCN_kanal&action=edit&redlink=1" class="new" title="HCN kanal (stranica ne postoji)">HCN</a></i> <ul><li><a href="/w/index.php?title=Funny_current&action=edit&redlink=1" class="new" title="Funny current (stranica ne postoji)">FC</a></li> <li><a href="/w/index.php?title=HCN1&action=edit&redlink=1" class="new" title="HCN1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=HCN2&action=edit&redlink=1" class="new" title="HCN2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=HCN3&action=edit&redlink=1" class="new" title="HCN3 (stranica ne postoji)">3</a></li> <li><a href="/w/index.php?title=HCN4&action=edit&redlink=1" class="new" title="HCN4 (stranica ne postoji)">4</a></li></ul></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0px;width:auto;"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=TRPA_(kanal)&action=edit&redlink=1" class="new" title="TRPA (kanal) (stranica ne postoji)">TRPA</a> (<a href="/w/index.php?title=Transient_receptor_potential_cation_channel,_member_A1&action=edit&redlink=1" class="new" title="Transient receptor potential cation channel, member A1 (stranica ne postoji)">1</a>)</li> <li><a href="/w/index.php?title=TRPC&action=edit&redlink=1" class="new" title="TRPC (stranica ne postoji)">TRPC</a> <ul><li><a href="/w/index.php?title=TRPC1&action=edit&redlink=1" class="new" title="TRPC1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=TRPC2&action=edit&redlink=1" class="new" title="TRPC2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=TRPC3&action=edit&redlink=1" class="new" title="TRPC3 (stranica ne postoji)">3</a></li> <li><a href="/w/index.php?title=TRPC4&action=edit&redlink=1" class="new" title="TRPC4 (stranica ne postoji)">4</a></li> <li><a href="/w/index.php?title=TRPC4AP&action=edit&redlink=1" class="new" title="TRPC4AP (stranica ne postoji)">4AP</a></li> <li><a href="/w/index.php?title=TRPC5&action=edit&redlink=1" class="new" title="TRPC5 (stranica ne postoji)">5</a></li> <li><a href="/wiki/TRPC6" title="TRPC6">6</a></li> <li><a href="/w/index.php?title=TRPC7&action=edit&redlink=1" class="new" title="TRPC7 (stranica ne postoji)">7</a></li></ul></li> <li><a href="/w/index.php?title=TRPM&action=edit&redlink=1" class="new" title="TRPM (stranica ne postoji)">TRPM</a> <ul><li><a href="/w/index.php?title=TRPM1&action=edit&redlink=1" class="new" title="TRPM1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=TRPM2&action=edit&redlink=1" class="new" title="TRPM2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=TRPM3&action=edit&redlink=1" class="new" title="TRPM3 (stranica ne postoji)">3</a></li> <li><a href="/w/index.php?title=TRPM4&action=edit&redlink=1" class="new" title="TRPM4 (stranica ne postoji)">4</a></li> <li><a href="/w/index.php?title=TRPM5&action=edit&redlink=1" class="new" title="TRPM5 (stranica ne postoji)">5</a></li> <li><a href="/w/index.php?title=TRPM6&action=edit&redlink=1" class="new" title="TRPM6 (stranica ne postoji)">6</a></li> <li><a href="/w/index.php?title=TRPM7&action=edit&redlink=1" class="new" title="TRPM7 (stranica ne postoji)">7</a></li> <li><a href="/w/index.php?title=TRPM8&action=edit&redlink=1" class="new" title="TRPM8 (stranica ne postoji)">8</a></li></ul></li> <li><a href="/w/index.php?title=TRPML&action=edit&redlink=1" class="new" title="TRPML (stranica ne postoji)">TRPML</a> <ul><li><a href="/w/index.php?title=Mucolipin-1&action=edit&redlink=1" class="new" title="Mucolipin-1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=MCOLN2&action=edit&redlink=1" class="new" title="MCOLN2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=MCOLN3&action=edit&redlink=1" class="new" title="MCOLN3 (stranica ne postoji)">3</a></li></ul></li> <li><a href="/w/index.php?title=TRPN&action=edit&redlink=1" class="new" title="TRPN (stranica ne postoji)">TRPN</a></li> <li><a href="/w/index.php?title=TRPP&action=edit&redlink=1" class="new" title="TRPP (stranica ne postoji)">TRPP</a> <ul><li><a href="/w/index.php?title=PKD1&action=edit&redlink=1" class="new" title="PKD1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=Polycystic_kidney_disease_2&action=edit&redlink=1" class="new" title="Polycystic kidney disease 2 (stranica ne postoji)">2</a></li></ul></li> <li><a href="/w/index.php?title=TRPV&action=edit&redlink=1" class="new" title="TRPV (stranica ne postoji)">TRPV</a> <ul><li><a href="/wiki/TRPV1" title="TRPV1">1</a></li> <li><a href="/w/index.php?title=TRPV2&action=edit&redlink=1" class="new" title="TRPV2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=TRPV3&action=edit&redlink=1" class="new" title="TRPV3 (stranica ne postoji)">3</a></li> <li><a href="/w/index.php?title=TRPV4&action=edit&redlink=1" class="new" title="TRPV4 (stranica ne postoji)">4</a></li> <li><a href="/w/index.php?title=TRPV5&action=edit&redlink=1" class="new" title="TRPV5 (stranica ne postoji)">5</a></li> <li><a href="/w/index.php?title=TRPV6&action=edit&redlink=1" class="new" title="TRPV6 (stranica ne postoji)">6</a></li></ul></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px;width:auto;;background-color: AntiqueWhite;"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Aquaporin&action=edit&redlink=1" class="new" title="Aquaporin (stranica ne postoji)">Aquaporin</a> <ul><li><a href="/w/index.php?title=MIP_(gene)&action=edit&redlink=1" class="new" title="MIP (gene) (stranica ne postoji)">0</a></li> <li><a href="/w/index.php?title=Aquaporin_1&action=edit&redlink=1" class="new" title="Aquaporin 1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=Aquaporin_2&action=edit&redlink=1" class="new" title="Aquaporin 2 (stranica ne postoji)">2</a></li> <li><a href="/wiki/Aquaporin_3" class="mw-redirect" title="Aquaporin 3">3</a></li> <li><a href="/w/index.php?title=Aquaporin_4&action=edit&redlink=1" class="new" title="Aquaporin 4 (stranica ne postoji)">4</a></li> <li><a href="/w/index.php?title=AQP5&action=edit&redlink=1" class="new" title="AQP5 (stranica ne postoji)">5</a></li> <li><a href="/w/index.php?title=AQP6&action=edit&redlink=1" class="new" title="AQP6 (stranica ne postoji)">6</a></li> <li><a href="/w/index.php?title=AQP7&action=edit&redlink=1" class="new" title="AQP7 (stranica ne postoji)">7</a></li> <li><a href="/w/index.php?title=AQP8&action=edit&redlink=1" class="new" title="AQP8 (stranica ne postoji)">8</a></li> <li><a href="/w/index.php?title=AQP9&action=edit&redlink=1" class="new" title="AQP9 (stranica ne postoji)">9</a></li></ul></li> <li><a href="/w/index.php?title=Voltage-dependent_anion_channel&action=edit&redlink=1" class="new" title="Voltage-dependent anion channel (stranica ne postoji)">Voltage-dependent anion channel</a> <ul><li><a href="/w/index.php?title=VDAC1&action=edit&redlink=1" class="new" title="VDAC1 (stranica ne postoji)">1</a></li> <li><a href="/w/index.php?title=VDAC2&action=edit&redlink=1" class="new" title="VDAC2 (stranica ne postoji)">2</a></li> <li><a href="/w/index.php?title=VDAC3&action=edit&redlink=1" class="new" title="VDAC3 (stranica ne postoji)">3</a></li></ul></li> <li><a href="/w/index.php?title=General_bacterial_porin_family&action=edit&redlink=1" class="new" title="General bacterial porin family (stranica ne postoji)">General bacterial porin family</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0px;width:auto;"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Connexin&action=edit&redlink=1" class="new" title="Connexin (stranica ne postoji)">Connexin</a> <ul><li>A <ul><li><a href="/wiki/GJA1" class="mw-redirect" title="GJA1">GJA1</a></li> <li><a href="/w/index.php?title=GJA3&action=edit&redlink=1" class="new" title="GJA3 (stranica ne postoji)">GJA3</a></li> <li><a href="/w/index.php?title=GJA4&action=edit&redlink=1" class="new" title="GJA4 (stranica ne postoji)">GJA4</a></li> <li><a href="/w/index.php?title=GJA5&action=edit&redlink=1" class="new" title="GJA5 (stranica ne postoji)">GJA5</a></li> <li><a href="/w/index.php?title=GJA8&action=edit&redlink=1" class="new" title="GJA8 (stranica ne postoji)">GJA8</a></li> <li><a href="/w/index.php?title=GJD2&action=edit&redlink=1" class="new" title="GJD2 (stranica ne postoji)">GJA9</a></li> <li><a href="/w/index.php?title=GJA10&action=edit&redlink=1" class="new" title="GJA10 (stranica ne postoji)">GJA10</a></li></ul></li> <li>B <ul><li><a href="/wiki/GJB1" title="GJB1">GJB1</a></li> <li><a href="/wiki/GJB2" title="GJB2">GJB2</a></li> <li><a href="/wiki/GJB3" title="GJB3">GJB3</a></li> <li><a href="/wiki/GJB4" title="GJB4">GJB4</a></li> <li><a href="/w/index.php?title=GJB5&action=edit&redlink=1" class="new" title="GJB5 (stranica ne postoji)">GJB5</a></li> <li><a href="/wiki/GJB6" title="GJB6">GJB6</a></li> <li><a href="/w/index.php?title=GJB7&action=edit&redlink=1" class="new" title="GJB7 (stranica ne postoji)">GJB7</a></li></ul></li> <li>C <ul><li><a href="/w/index.php?title=GJC1&action=edit&redlink=1" class="new" title="GJC1 (stranica ne postoji)">GJC1</a></li> <li><a href="/w/index.php?title=GJC2&action=edit&redlink=1" class="new" title="GJC2 (stranica ne postoji)">GJC2</a></li> <li><a href="/w/index.php?title=GJC3&action=edit&redlink=1" class="new" title="GJC3 (stranica ne postoji)">GJC3</a></li></ul></li> <li>D <ul><li><a href="/w/index.php?title=GJD2&action=edit&redlink=1" class="new" title="GJD2 (stranica ne postoji)">GJD2</a></li> <li><a href="/w/index.php?title=GJD3&action=edit&redlink=1" class="new" title="GJD3 (stranica ne postoji)">GJD3</a></li> <li><a href="/w/index.php?title=GJD4&action=edit&redlink=1" class="new" title="GJD4 (stranica ne postoji)">GJD4</a></li></ul></li></ul></li> <li><a href="/w/index.php?title=Innexin&action=edit&redlink=1" class="new" title="Innexin (stranica ne postoji)">Innexin</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks mw-collapsible autocollapse navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style=";"><div id="By_gating_mechanism" style="font-size:114%;margin:0 4em"><i>By gating mechanism</i></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px;width:auto;;background-color: AntiqueWhite;"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Ligand-gated_ion_channel&action=edit&redlink=1" class="new" title="Ligand-gated ion channel (stranica ne postoji)">Ligand-gated</a></li> <li><a href="/w/index.php?title=Light-gated_ion_channel&action=edit&redlink=1" class="new" title="Light-gated ion channel (stranica ne postoji)">Light-gated</a></li> <li><a href="/w/index.php?title=Voltage-gated_ion_channel&action=edit&redlink=1" class="new" title="Voltage-gated ion channel (stranica ne postoji)">Voltage-gated</a></li> <li><a href="/w/index.php?title=Stretch-activated_ion_channel&action=edit&redlink=1" class="new" title="Stretch-activated ion channel (stranica ne postoji)">Stretch-activated</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite; padding: 0px;"><div><i>također pogledati <a href="/wiki/%C5%A0ablon:Kanalopatije" title="Šablon:Kanalopatije">poremećaji</a></i></div></td></tr></tbody></table></div> <p><i>Ovaj članak uključuje tekst iz <a href="/wiki/Nacionalna_medicinska_biblioteka_Sjedinjenih_Dr%C5%BEava" class="mw-redirect" title="Nacionalna medicinska biblioteka Sjedinjenih Država">Nacionalne medicinske biblioteke Sjedinjenih Država</a>, koji je u <a href="/wiki/Javno_vlasni%C5%A1tvo" title="Javno vlasništvo">javnom vlasništvu</a>.</i> </p></div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Preuzeto iz "<a dir="ltr" href="https://bs.wikipedia.org/w/index.php?title=SCN1A&oldid=3534928">https://bs.wikipedia.org/w/index.php?title=SCN1A&oldid=3534928</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Posebno:Kategorije" title="Posebno:Kategorije">Kategorije</a>: <ul><li><a href="/wiki/Kategorija:Geni_na_hromosomu_2" title="Kategorija:Geni na hromosomu 2">Geni na hromosomu 2</a></li><li><a href="/w/index.php?title=Kategorija:Wikipedia_%C4%8Dlanci_koji_uklju%C4%8Duju_tekst_iz_Nacionalne_medicinske_biblioteke_Sjedinjenih_Dr%C5%BEava&action=edit&redlink=1" class="new" title="Kategorija:Wikipedia članci koji uključuju tekst iz Nacionalne medicinske biblioteke Sjedinjenih Država (stranica ne postoji)">Wikipedia članci koji uključuju tekst iz Nacionalne medicinske biblioteke Sjedinjenih Država</a></li><li><a href="/wiki/Kategorija:Ionski_kanali" title="Kategorija:Ionski kanali">Ionski kanali</a></li><li><a href="/wiki/Kategorija:Ljudski_proteini" title="Kategorija:Ljudski proteini">Ljudski proteini</a></li><li><a href="/wiki/Kategorija:Proteomika" title="Kategorija:Proteomika">Proteomika</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Sakrivena kategorija: <ul><li><a href="/wiki/Kategorija:Webarchive_template_wayback_links" title="Kategorija:Webarchive template wayback links">Webarchive template 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