CINXE.COM
The Nobel Prize in Physiology or Medicine 1967 - NobelPrize.org
<!DOCTYPE html> <html lang="en-US" class="no-js"> <head> <meta charset="UTF-8"><script type="text/javascript">(window.NREUM||(NREUM={})).init={privacy:{cookies_enabled:true},ajax:{deny_list:["bam.eu01.nr-data.net"]},distributed_tracing:{enabled:true}};(window.NREUM||(NREUM={})).loader_config={agentID:"212354677",accountID:"3196970",trustKey:"3196970",xpid:"VwcOV19UCBACVVNRAgUCUlc=",licenseKey:"NRJS-0940f7eaf4cb46e1cfe",applicationID:"212354543"};;/*! For license information please see nr-loader-spa-1.274.0.min.js.LICENSE.txt */ (()=>{var e,t,r={8122:(e,t,r)=>{"use strict";r.d(t,{a:()=>i});var n=r(944);function i(e,t){try{if(!e||"object"!=typeof e)return(0,n.R)(3);if(!t||"object"!=typeof t)return(0,n.R)(4);const r=Object.create(Object.getPrototypeOf(t),Object.getOwnPropertyDescriptors(t)),o=0===Object.keys(r).length?e:r;for(let a in o)if(void 0!==e[a])try{if(null===e[a]){r[a]=null;continue}Array.isArray(e[a])&&Array.isArray(t[a])?r[a]=Array.from(new Set([...e[a],...t[a]])):"object"==typeof e[a]&&"object"==typeof t[a]?r[a]=i(e[a],t[a]):r[a]=e[a]}catch(e){(0,n.R)(1,e)}return r}catch(e){(0,n.R)(2,e)}}},2555:(e,t,r)=>{"use strict";r.d(t,{Vp:()=>c,fn:()=>s,x1:()=>u});var n=r(384),i=r(8122);const o={beacon:n.NT.beacon,errorBeacon:n.NT.errorBeacon,licenseKey:void 0,applicationID:void 0,sa:void 0,queueTime:void 0,applicationTime:void 0,ttGuid:void 0,user:void 0,account:void 0,product:void 0,extra:void 0,jsAttributes:{},userAttributes:void 0,atts:void 0,transactionName:void 0,tNamePlain:void 0},a={};function s(e){try{const t=c(e);return!!t.licenseKey&&!!t.errorBeacon&&!!t.applicationID}catch(e){return!1}}function c(e){if(!e)throw new Error("All info objects require an agent identifier!");if(!a[e])throw new Error("Info for ".concat(e," was never set"));return a[e]}function u(e,t){if(!e)throw new Error("All info objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.info=a[e])}},9417:(e,t,r)=>{"use strict";r.d(t,{D0:()=>h,gD:()=>g,xN:()=>p});var n=r(993);const i=e=>{if(!e||"string"!=typeof e)return!1;try{document.createDocumentFragment().querySelector(e)}catch{return!1}return!0};var o=r(2614),a=r(944),s=r(384),c=r(8122);const u="[data-nr-mask]",d=()=>{const e={mask_selector:"*",block_selector:"[data-nr-block]",mask_input_options:{color:!1,date:!1,"datetime-local":!1,email:!1,month:!1,number:!1,range:!1,search:!1,tel:!1,text:!1,time:!1,url:!1,week:!1,textarea:!1,select:!1,password:!0}};return{ajax:{deny_list:void 0,block_internal:!0,enabled:!0,harvestTimeSeconds:10,autoStart:!0},distributed_tracing:{enabled:void 0,exclude_newrelic_header:void 0,cors_use_newrelic_header:void 0,cors_use_tracecontext_headers:void 0,allowed_origins:void 0},feature_flags:[],generic_events:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},harvest:{tooManyRequestsDelay:60},jserrors:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},logging:{enabled:!0,harvestTimeSeconds:10,autoStart:!0,level:n.p_.INFO},metrics:{enabled:!0,autoStart:!0},obfuscate:void 0,page_action:{enabled:!0},page_view_event:{enabled:!0,autoStart:!0},page_view_timing:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},performance:{capture_marks:!1,capture_measures:!1},privacy:{cookies_enabled:!0},proxy:{assets:void 0,beacon:void 0},session:{expiresMs:o.wk,inactiveMs:o.BB},session_replay:{autoStart:!0,enabled:!1,harvestTimeSeconds:60,preload:!1,sampling_rate:10,error_sampling_rate:100,collect_fonts:!1,inline_images:!1,fix_stylesheets:!0,mask_all_inputs:!0,get mask_text_selector(){return e.mask_selector},set mask_text_selector(t){i(t)?e.mask_selector="".concat(t,",").concat(u):""===t||null===t?e.mask_selector=u:(0,a.R)(5,t)},get block_class(){return"nr-block"},get ignore_class(){return"nr-ignore"},get mask_text_class(){return"nr-mask"},get block_selector(){return e.block_selector},set block_selector(t){i(t)?e.block_selector+=",".concat(t):""!==t&&(0,a.R)(6,t)},get mask_input_options(){return e.mask_input_options},set mask_input_options(t){t&&"object"==typeof t?e.mask_input_options={...t,password:!0}:(0,a.R)(7,t)}},session_trace:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},soft_navigations:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},spa:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},ssl:void 0,user_actions:{enabled:!0}}},l={},f="All configuration objects require an agent identifier!";function h(e){if(!e)throw new Error(f);if(!l[e])throw new Error("Configuration for ".concat(e," was never set"));return l[e]}function p(e,t){if(!e)throw new Error(f);l[e]=(0,c.a)(t,d());const r=(0,s.nY)(e);r&&(r.init=l[e])}function g(e,t){if(!e)throw new Error(f);var r=h(e);if(r){for(var n=t.split("."),i=0;i<n.length-1;i++)if("object"!=typeof(r=r[n[i]]))return;r=r[n[n.length-1]]}return r}},5603:(e,t,r)=>{"use strict";r.d(t,{a:()=>c,o:()=>s});var n=r(384),i=r(8122);const o={accountID:void 0,trustKey:void 0,agentID:void 0,licenseKey:void 0,applicationID:void 0,xpid:void 0},a={};function s(e){if(!e)throw new Error("All loader-config objects require an agent identifier!");if(!a[e])throw new Error("LoaderConfig for ".concat(e," was never set"));return a[e]}function c(e,t){if(!e)throw new Error("All loader-config objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.loader_config=a[e])}},3371:(e,t,r)=>{"use strict";r.d(t,{V:()=>f,f:()=>l});var n=r(8122),i=r(384),o=r(6154),a=r(9324);let s=0;const c={buildEnv:a.F3,distMethod:a.Xs,version:a.xv,originTime:o.WN},u={customTransaction:void 0,disabled:!1,isolatedBacklog:!1,loaderType:void 0,maxBytes:3e4,onerror:void 0,ptid:void 0,releaseIds:{},appMetadata:{},session:void 0,denyList:void 0,timeKeeper:void 0,obfuscator:void 0},d={};function l(e){if(!e)throw new Error("All runtime objects require an agent identifier!");if(!d[e])throw new Error("Runtime for ".concat(e," was never set"));return d[e]}function f(e,t){if(!e)throw new Error("All runtime objects require an agent identifier!");d[e]={...(0,n.a)(t,u),...c},Object.hasOwnProperty.call(d[e],"harvestCount")||Object.defineProperty(d[e],"harvestCount",{get:()=>++s});const r=(0,i.nY)(e);r&&(r.runtime=d[e])}},9324:(e,t,r)=>{"use strict";r.d(t,{F3:()=>i,Xs:()=>o,Yq:()=>a,xv:()=>n});const n="1.274.0",i="PROD",o="CDN",a="^2.0.0-alpha.17"},6154:(e,t,r)=>{"use strict";r.d(t,{A4:()=>s,OF:()=>d,RI:()=>i,WN:()=>h,bv:()=>o,gm:()=>a,lR:()=>f,m:()=>u,mw:()=>c,sb:()=>l});var n=r(1863);const i="undefined"!=typeof window&&!!window.document,o="undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self.navigator instanceof WorkerNavigator||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis.navigator instanceof WorkerNavigator),a=i?window:"undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis),s="complete"===a?.document?.readyState,c=Boolean("hidden"===a?.document?.visibilityState),u=""+a?.location,d=/iPad|iPhone|iPod/.test(a.navigator?.userAgent),l=d&&"undefined"==typeof SharedWorker,f=(()=>{const e=a.navigator?.userAgent?.match(/Firefox[/\s](\d+\.\d+)/);return Array.isArray(e)&&e.length>=2?+e[1]:0})(),h=Date.now()-(0,n.t)()},7295:(e,t,r)=>{"use strict";r.d(t,{Xv:()=>a,gX:()=>i,iW:()=>o});var n=[];function i(e){if(!e||o(e))return!1;if(0===n.length)return!0;for(var t=0;t<n.length;t++){var r=n[t];if("*"===r.hostname)return!1;if(s(r.hostname,e.hostname)&&c(r.pathname,e.pathname))return!1}return!0}function o(e){return void 0===e.hostname}function a(e){if(n=[],e&&e.length)for(var t=0;t<e.length;t++){let r=e[t];if(!r)continue;0===r.indexOf("http://")?r=r.substring(7):0===r.indexOf("https://")&&(r=r.substring(8));const i=r.indexOf("/");let o,a;i>0?(o=r.substring(0,i),a=r.substring(i)):(o=r,a="");let[s]=o.split(":");n.push({hostname:s,pathname:a})}}function s(e,t){return!(e.length>t.length)&&t.indexOf(e)===t.length-e.length}function c(e,t){return 0===e.indexOf("/")&&(e=e.substring(1)),0===t.indexOf("/")&&(t=t.substring(1)),""===e||e===t}},1687:(e,t,r)=>{"use strict";r.d(t,{Ak:()=>c,Ze:()=>l,x3:()=>u});var n=r(7836),i=r(3606),o=r(860),a=r(2646);const s={};function c(e,t){const r={staged:!1,priority:o.P3[t]||0};d(e),s[e].get(t)||s[e].set(t,r)}function u(e,t){e&&s[e]&&(s[e].get(t)&&s[e].delete(t),h(e,t,!1),s[e].size&&f(e))}function d(e){if(!e)throw new Error("agentIdentifier required");s[e]||(s[e]=new Map)}function l(e="",t="feature",r=!1){if(d(e),!e||!s[e].get(t)||r)return h(e,t);s[e].get(t).staged=!0,f(e)}function f(e){const t=Array.from(s[e]);t.every((([e,t])=>t.staged))&&(t.sort(((e,t)=>e[1].priority-t[1].priority)),t.forEach((([t])=>{s[e].delete(t),h(e,t)})))}function h(e,t,r=!0){const o=e?n.ee.get(e):n.ee,s=i.i.handlers;if(!o.aborted&&o.backlog&&s){if(r){const e=o.backlog[t],r=s[t];if(r){for(let t=0;e&&t<e.length;++t)p(e[t],r);Object.entries(r).forEach((([e,t])=>{Object.values(t||{}).forEach((t=>{t[0]?.on&&t[0]?.context()instanceof a.y&&t[0].on(e,t[1])}))}))}}o.isolatedBacklog||delete s[t],o.backlog[t]=null,o.emit("drain-"+t,[])}}function p(e,t){var r=e[1];Object.values(t[r]||{}).forEach((t=>{var r=e[0];if(t[0]===r){var n=t[1],i=e[3],o=e[2];n.apply(i,o)}}))}},7836:(e,t,r)=>{"use strict";r.d(t,{P:()=>c,ee:()=>u});var n=r(384),i=r(8990),o=r(3371),a=r(2646),s=r(5607);const c="nr@context:".concat(s.W),u=function e(t,r){var n={},s={},d={},l=!1;try{l=16===r.length&&(0,o.f)(r).isolatedBacklog}catch(e){}var f={on:p,addEventListener:p,removeEventListener:function(e,t){var r=n[e];if(!r)return;for(var i=0;i<r.length;i++)r[i]===t&&r.splice(i,1)},emit:function(e,r,n,i,o){!1!==o&&(o=!0);if(u.aborted&&!i)return;t&&o&&t.emit(e,r,n);for(var a=h(n),c=g(e),d=c.length,l=0;l<d;l++)c[l].apply(a,r);var p=v()[s[e]];p&&p.push([f,e,r,a]);return a},get:m,listeners:g,context:h,buffer:function(e,t){const r=v();if(t=t||"feature",f.aborted)return;Object.entries(e||{}).forEach((([e,n])=>{s[n]=t,t in r||(r[t]=[])}))},abort:function(){f._aborted=!0,Object.keys(f.backlog).forEach((e=>{delete f.backlog[e]}))},isBuffering:function(e){return!!v()[s[e]]},debugId:r,backlog:l?{}:t&&"object"==typeof t.backlog?t.backlog:{},isolatedBacklog:l};return Object.defineProperty(f,"aborted",{get:()=>{let e=f._aborted||!1;return e||(t&&(e=t.aborted),e)}}),f;function h(e){return e&&e instanceof a.y?e:e?(0,i.I)(e,c,(()=>new a.y(c))):new a.y(c)}function p(e,t){n[e]=g(e).concat(t)}function g(e){return n[e]||[]}function m(t){return d[t]=d[t]||e(f,t)}function v(){return f.backlog}}(void 0,"globalEE"),d=(0,n.Zm)();d.ee||(d.ee=u)},2646:(e,t,r)=>{"use strict";r.d(t,{y:()=>n});class n{constructor(e){this.contextId=e}}},9908:(e,t,r)=>{"use strict";r.d(t,{d:()=>n,p:()=>i});var n=r(7836).ee.get("handle");function i(e,t,r,i,o){o?(o.buffer([e],i),o.emit(e,t,r)):(n.buffer([e],i),n.emit(e,t,r))}},3606:(e,t,r)=>{"use strict";r.d(t,{i:()=>o});var n=r(9908);o.on=a;var i=o.handlers={};function o(e,t,r,o){a(o||n.d,i,e,t,r)}function a(e,t,r,i,o){o||(o="feature"),e||(e=n.d);var a=t[o]=t[o]||{};(a[r]=a[r]||[]).push([e,i])}},3878:(e,t,r)=>{"use strict";function n(e,t){return{capture:e,passive:!1,signal:t}}function i(e,t,r=!1,i){window.addEventListener(e,t,n(r,i))}function o(e,t,r=!1,i){document.addEventListener(e,t,n(r,i))}r.d(t,{DD:()=>o,jT:()=>n,sp:()=>i})},5607:(e,t,r)=>{"use strict";r.d(t,{W:()=>n});const n=(0,r(9566).bz)()},9566:(e,t,r)=>{"use strict";r.d(t,{LA:()=>s,ZF:()=>c,bz:()=>a,el:()=>u});var n=r(6154);const i="xxxxxxxx-xxxx-4xxx-yxxx-xxxxxxxxxxxx";function o(e,t){return e?15&e[t]:16*Math.random()|0}function a(){const e=n.gm?.crypto||n.gm?.msCrypto;let t,r=0;return e&&e.getRandomValues&&(t=e.getRandomValues(new Uint8Array(30))),i.split("").map((e=>"x"===e?o(t,r++).toString(16):"y"===e?(3&o()|8).toString(16):e)).join("")}function s(e){const t=n.gm?.crypto||n.gm?.msCrypto;let r,i=0;t&&t.getRandomValues&&(r=t.getRandomValues(new Uint8Array(e)));const a=[];for(var s=0;s<e;s++)a.push(o(r,i++).toString(16));return a.join("")}function c(){return s(16)}function u(){return s(32)}},2614:(e,t,r)=>{"use strict";r.d(t,{BB:()=>a,H3:()=>n,g:()=>u,iL:()=>c,tS:()=>s,uh:()=>i,wk:()=>o});const n="NRBA",i="SESSION",o=144e5,a=18e5,s={STARTED:"session-started",PAUSE:"session-pause",RESET:"session-reset",RESUME:"session-resume",UPDATE:"session-update"},c={SAME_TAB:"same-tab",CROSS_TAB:"cross-tab"},u={OFF:0,FULL:1,ERROR:2}},1863:(e,t,r)=>{"use strict";function n(){return Math.floor(performance.now())}r.d(t,{t:()=>n})},7485:(e,t,r)=>{"use strict";r.d(t,{D:()=>i});var n=r(6154);function i(e){if(0===(e||"").indexOf("data:"))return{protocol:"data"};try{const t=new URL(e,location.href),r={port:t.port,hostname:t.hostname,pathname:t.pathname,search:t.search,protocol:t.protocol.slice(0,t.protocol.indexOf(":")),sameOrigin:t.protocol===n.gm?.location?.protocol&&t.host===n.gm?.location?.host};return r.port&&""!==r.port||("http:"===t.protocol&&(r.port="80"),"https:"===t.protocol&&(r.port="443")),r.pathname&&""!==r.pathname?r.pathname.startsWith("/")||(r.pathname="/".concat(r.pathname)):r.pathname="/",r}catch(e){return{}}}},944:(e,t,r)=>{"use strict";function n(e,t){"function"==typeof console.debug&&console.debug("New Relic Warning: https://github.com/newrelic/newrelic-browser-agent/blob/main/docs/warning-codes.md#".concat(e),t)}r.d(t,{R:()=>n})},5284:(e,t,r)=>{"use strict";r.d(t,{t:()=>c,B:()=>s});var n=r(7836),i=r(6154);const o="newrelic";const a=new Set,s={};function c(e,t){const r=n.ee.get(t);s[t]??={},e&&"object"==typeof e&&(a.has(t)||(r.emit("rumresp",[e]),s[t]=e,a.add(t),function(e={}){try{i.gm.dispatchEvent(new CustomEvent(o,{detail:e}))}catch(e){}}({loaded:!0})))}},8990:(e,t,r)=>{"use strict";r.d(t,{I:()=>i});var n=Object.prototype.hasOwnProperty;function i(e,t,r){if(n.call(e,t))return e[t];var i=r();if(Object.defineProperty&&Object.keys)try{return Object.defineProperty(e,t,{value:i,writable:!0,enumerable:!1}),i}catch(e){}return e[t]=i,i}},6389:(e,t,r)=>{"use strict";function n(e,t=500,r={}){const n=r?.leading||!1;let i;return(...r)=>{n&&void 0===i&&(e.apply(this,r),i=setTimeout((()=>{i=clearTimeout(i)}),t)),n||(clearTimeout(i),i=setTimeout((()=>{e.apply(this,r)}),t))}}function i(e){let t=!1;return(...r)=>{t||(t=!0,e.apply(this,r))}}r.d(t,{J:()=>i,s:()=>n})},3304:(e,t,r)=>{"use strict";r.d(t,{A:()=>o});var n=r(7836);const i=()=>{const e=new WeakSet;return(t,r)=>{if("object"==typeof r&&null!==r){if(e.has(r))return;e.add(r)}return r}};function o(e){try{return JSON.stringify(e,i())??""}catch(e){try{n.ee.emit("internal-error",[e])}catch(e){}return""}}},5289:(e,t,r)=>{"use strict";r.d(t,{GG:()=>o,sB:()=>a});var n=r(3878);function i(){return"undefined"==typeof document||"complete"===document.readyState}function o(e,t){if(i())return e();(0,n.sp)("load",e,t)}function a(e){if(i())return e();(0,n.DD)("DOMContentLoaded",e)}},384:(e,t,r)=>{"use strict";r.d(t,{NT:()=>o,US:()=>d,Zm:()=>a,bQ:()=>c,dV:()=>s,nY:()=>u,pV:()=>l});var n=r(6154),i=r(1863);const o={beacon:"bam.nr-data.net",errorBeacon:"bam.nr-data.net"};function a(){return n.gm.NREUM||(n.gm.NREUM={}),void 0===n.gm.newrelic&&(n.gm.newrelic=n.gm.NREUM),n.gm.NREUM}function s(){let e=a();return e.o||(e.o={ST:n.gm.setTimeout,SI:n.gm.setImmediate,CT:n.gm.clearTimeout,XHR:n.gm.XMLHttpRequest,REQ:n.gm.Request,EV:n.gm.Event,PR:n.gm.Promise,MO:n.gm.MutationObserver,FETCH:n.gm.fetch,WS:n.gm.WebSocket}),e}function c(e,t){let r=a();r.initializedAgents??={},t.initializedAt={ms:(0,i.t)(),date:new Date},r.initializedAgents[e]=t}function u(e){let t=a();return t.initializedAgents?.[e]}function d(e,t){a()[e]=t}function l(){return function(){let e=a();const t=e.info||{};e.info={beacon:o.beacon,errorBeacon:o.errorBeacon,...t}}(),function(){let e=a();const t=e.init||{};e.init={...t}}(),s(),function(){let e=a();const t=e.loader_config||{};e.loader_config={...t}}(),a()}},2843:(e,t,r)=>{"use strict";r.d(t,{u:()=>i});var n=r(3878);function i(e,t=!1,r,i){(0,n.DD)("visibilitychange",(function(){if(t)return void("hidden"===document.visibilityState&&e());e(document.visibilityState)}),r,i)}},8139:(e,t,r)=>{"use strict";r.d(t,{u:()=>f});var n=r(7836),i=r(3434),o=r(8990),a=r(6154);const s={},c=a.gm.XMLHttpRequest,u="addEventListener",d="removeEventListener",l="nr@wrapped:".concat(n.P);function f(e){var t=function(e){return(e||n.ee).get("events")}(e);if(s[t.debugId]++)return t;s[t.debugId]=1;var r=(0,i.YM)(t,!0);function f(e){r.inPlace(e,[u,d],"-",p)}function p(e,t){return e[1]}return"getPrototypeOf"in Object&&(a.RI&&h(document,f),h(a.gm,f),h(c.prototype,f)),t.on(u+"-start",(function(e,t){var n=e[1];if(null!==n&&("function"==typeof n||"object"==typeof n)){var i=(0,o.I)(n,l,(function(){var e={object:function(){if("function"!=typeof n.handleEvent)return;return n.handleEvent.apply(n,arguments)},function:n}[typeof n];return e?r(e,"fn-",null,e.name||"anonymous"):n}));this.wrapped=e[1]=i}})),t.on(d+"-start",(function(e){e[1]=this.wrapped||e[1]})),t}function h(e,t,...r){let n=e;for(;"object"==typeof n&&!Object.prototype.hasOwnProperty.call(n,u);)n=Object.getPrototypeOf(n);n&&t(n,...r)}},3434:(e,t,r)=>{"use strict";r.d(t,{Jt:()=>o,YM:()=>c});var n=r(7836),i=r(5607);const o="nr@original:".concat(i.W);var a=Object.prototype.hasOwnProperty,s=!1;function c(e,t){return e||(e=n.ee),r.inPlace=function(e,t,n,i,o){n||(n="");const a="-"===n.charAt(0);for(let s=0;s<t.length;s++){const c=t[s],u=e[c];d(u)||(e[c]=r(u,a?c+n:n,i,c,o))}},r.flag=o,r;function r(t,r,n,s,c){return d(t)?t:(r||(r=""),nrWrapper[o]=t,function(e,t,r){if(Object.defineProperty&&Object.keys)try{return Object.keys(e).forEach((function(r){Object.defineProperty(t,r,{get:function(){return e[r]},set:function(t){return e[r]=t,t}})})),t}catch(e){u([e],r)}for(var n in e)a.call(e,n)&&(t[n]=e[n])}(t,nrWrapper,e),nrWrapper);function nrWrapper(){var o,a,d,l;try{a=this,o=[...arguments],d="function"==typeof n?n(o,a):n||{}}catch(t){u([t,"",[o,a,s],d],e)}i(r+"start",[o,a,s],d,c);try{return l=t.apply(a,o)}catch(e){throw i(r+"err",[o,a,e],d,c),e}finally{i(r+"end",[o,a,l],d,c)}}}function i(r,n,i,o){if(!s||t){var a=s;s=!0;try{e.emit(r,n,i,t,o)}catch(t){u([t,r,n,i],e)}s=a}}}function u(e,t){t||(t=n.ee);try{t.emit("internal-error",e)}catch(e){}}function d(e){return!(e&&"function"==typeof e&&e.apply&&!e[o])}},9300:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.ajax},3333:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,Zp:()=>i,mq:()=>s,nf:()=>a,qN:()=>o});const n=r(860).K7.genericEvents,i=["auxclick","click","copy","keydown","paste","scrollend"],o=["focus","blur"],a=4,s=1e3},6774:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.jserrors},993:(e,t,r)=>{"use strict";r.d(t,{ET:()=>o,TZ:()=>a,p_:()=>i});var n=r(860);const i={ERROR:"ERROR",WARN:"WARN",INFO:"INFO",DEBUG:"DEBUG",TRACE:"TRACE"},o="log",a=n.K7.logging},3785:(e,t,r)=>{"use strict";r.d(t,{R:()=>c,b:()=>u});var n=r(9908),i=r(1863),o=r(860),a=r(3969),s=r(993);function c(e,t,r={},c=s.p_.INFO){(0,n.p)(a.xV,["API/logging/".concat(c.toLowerCase(),"/called")],void 0,o.K7.metrics,e),(0,n.p)(s.ET,[(0,i.t)(),t,r,c],void 0,o.K7.logging,e)}function u(e){return"string"==typeof e&&Object.values(s.p_).some((t=>t===e.toUpperCase().trim()))}},3969:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,XG:()=>s,rs:()=>i,xV:()=>a,z_:()=>o});const n=r(860).K7.metrics,i="sm",o="cm",a="storeSupportabilityMetrics",s="storeEventMetrics"},6630:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewEvent},782:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewTiming},6344:(e,t,r)=>{"use strict";r.d(t,{BB:()=>d,G4:()=>o,Qb:()=>l,TZ:()=>i,Ug:()=>a,_s:()=>s,bc:()=>u,yP:()=>c});var n=r(2614);const i=r(860).K7.sessionReplay,o={RECORD:"recordReplay",PAUSE:"pauseReplay",REPLAY_RUNNING:"replayRunning",ERROR_DURING_REPLAY:"errorDuringReplay"},a=.12,s={DomContentLoaded:0,Load:1,FullSnapshot:2,IncrementalSnapshot:3,Meta:4,Custom:5},c={[n.g.ERROR]:15e3,[n.g.FULL]:3e5,[n.g.OFF]:0},u={RESET:{message:"Session was reset",sm:"Reset"},IMPORT:{message:"Recorder failed to import",sm:"Import"},TOO_MANY:{message:"429: Too Many Requests",sm:"Too-Many"},TOO_BIG:{message:"Payload was too large",sm:"Too-Big"},CROSS_TAB:{message:"Session Entity was set to OFF on another tab",sm:"Cross-Tab"},ENTITLEMENTS:{message:"Session Replay is not allowed and will not be started",sm:"Entitlement"}},d=5e3,l={API:"api"}},5270:(e,t,r)=>{"use strict";r.d(t,{Aw:()=>c,CT:()=>u,SR:()=>s});var n=r(384),i=r(9417),o=r(7767),a=r(6154);function s(e){return!!(0,n.dV)().o.MO&&(0,o.V)(e)&&!0===(0,i.gD)(e,"session_trace.enabled")}function c(e){return!0===(0,i.gD)(e,"session_replay.preload")&&s(e)}function u(e,t){const r=t.correctAbsoluteTimestamp(e);return{originalTimestamp:e,correctedTimestamp:r,timestampDiff:e-r,originTime:a.WN,correctedOriginTime:t.correctedOriginTime,originTimeDiff:Math.floor(a.WN-t.correctedOriginTime)}}},3738:(e,t,r)=>{"use strict";r.d(t,{He:()=>i,Kp:()=>s,Lc:()=>u,Rz:()=>d,TZ:()=>n,bD:()=>o,d3:()=>a,jx:()=>l,uP:()=>c});const n=r(860).K7.sessionTrace,i="bstResource",o="resource",a="-start",s="-end",c="fn"+a,u="fn"+s,d="pushState",l=1e3},3962:(e,t,r)=>{"use strict";r.d(t,{AM:()=>o,O2:()=>s,Qu:()=>c,TZ:()=>a,ih:()=>u,tC:()=>i});var n=r(860);const i=["click","keydown","submit"],o="api",a=n.K7.softNav,s={INITIAL_PAGE_LOAD:"",ROUTE_CHANGE:1,UNSPECIFIED:2},c={INTERACTION:1,AJAX:2,CUSTOM_END:3,CUSTOM_TRACER:4},u={IP:"in progress",FIN:"finished",CAN:"cancelled"}},7378:(e,t,r)=>{"use strict";r.d(t,{$p:()=>x,BR:()=>b,Kp:()=>R,L3:()=>y,Lc:()=>c,NC:()=>o,SG:()=>d,TZ:()=>i,U6:()=>p,UT:()=>m,d3:()=>w,dT:()=>f,e5:()=>A,gx:()=>v,l9:()=>l,oW:()=>h,op:()=>g,rw:()=>u,tH:()=>E,uP:()=>s,wW:()=>T,xq:()=>a});var n=r(384);const i=r(860).K7.spa,o=["click","submit","keypress","keydown","keyup","change"],a=999,s="fn-start",c="fn-end",u="cb-start",d="api-ixn-",l="remaining",f="interaction",h="spaNode",p="jsonpNode",g="fetch-start",m="fetch-done",v="fetch-body-",b="jsonp-end",y=(0,n.dV)().o.ST,w="-start",R="-end",x="-body",T="cb"+R,A="jsTime",E="fetch"},4234:(e,t,r)=>{"use strict";r.d(t,{W:()=>o});var n=r(7836),i=r(1687);class o{constructor(e,t){this.agentIdentifier=e,this.ee=n.ee.get(e),this.featureName=t,this.blocked=!1}deregisterDrain(){(0,i.x3)(this.agentIdentifier,this.featureName)}}},7767:(e,t,r)=>{"use strict";r.d(t,{V:()=>o});var n=r(9417),i=r(6154);const o=e=>i.RI&&!0===(0,n.gD)(e,"privacy.cookies_enabled")},425:(e,t,r)=>{"use strict";r.d(t,{j:()=>j});var n=r(860),i=r(2555),o=r(3371),a=r(9908),s=r(7836),c=r(1687),u=r(5289),d=r(6154),l=r(944),f=r(3969),h=r(384),p=r(6344);const g=["setErrorHandler","finished","addToTrace","addRelease","addPageAction","setCurrentRouteName","setPageViewName","setCustomAttribute","interaction","noticeError","setUserId","setApplicationVersion","start",p.G4.RECORD,p.G4.PAUSE,"log","wrapLogger"],m=["setErrorHandler","finished","addToTrace","addRelease"];var v=r(1863),b=r(2614),y=r(993),w=r(3785),R=r(2646),x=r(3434);function T(e,t,r,n){if("object"!=typeof t||!t||"string"!=typeof r||!r||"function"!=typeof t[r])return(0,l.R)(29);const i=function(e){return(e||s.ee).get("logger")}(e),o=(0,x.YM)(i),a=new R.y(s.P);return a.level=n.level,a.customAttributes=n.customAttributes,o.inPlace(t,[r],"wrap-logger-",a),i}function A(){const e=(0,h.pV)();g.forEach((t=>{e[t]=(...r)=>function(t,...r){let n=[];return Object.values(e.initializedAgents).forEach((e=>{e&&e.api?e.exposed&&e.api[t]&&n.push(e.api[t](...r)):(0,l.R)(38,t)})),n.length>1?n:n[0]}(t,...r)}))}const E={};var S=r(9417),N=r(5603),O=r(5284);const _=e=>{const t=e.startsWith("http");e+="/",r.p=t?e:"https://"+e};let I=!1;function j(e,t={},g,R){let{init:x,info:j,loader_config:P,runtime:C={},exposed:k=!0}=t;C.loaderType=g;const L=(0,h.pV)();j||(x=L.init,j=L.info,P=L.loader_config),(0,S.xN)(e.agentIdentifier,x||{}),(0,N.a)(e.agentIdentifier,P||{}),j.jsAttributes??={},d.bv&&(j.jsAttributes.isWorker=!0),(0,i.x1)(e.agentIdentifier,j);const H=(0,S.D0)(e.agentIdentifier),D=[j.beacon,j.errorBeacon];I||(H.proxy.assets&&(_(H.proxy.assets),D.push(H.proxy.assets)),H.proxy.beacon&&D.push(H.proxy.beacon),A(),(0,h.US)("activatedFeatures",O.B),e.runSoftNavOverSpa&&=!0===H.soft_navigations.enabled&&H.feature_flags.includes("soft_nav")),C.denyList=[...H.ajax.deny_list||[],...H.ajax.block_internal?D:[]],C.ptid=e.agentIdentifier,(0,o.V)(e.agentIdentifier,C),e.ee=s.ee.get(e.agentIdentifier),void 0===e.api&&(e.api=function(e,t,h=!1){t||(0,c.Ak)(e,"api");const g={};var R=s.ee.get(e),x=R.get("tracer");E[e]=b.g.OFF,R.on(p.G4.REPLAY_RUNNING,(t=>{E[e]=t}));var A="api-",S=A+"ixn-";function N(t,r,n,o){const a=(0,i.Vp)(e);return null===r?delete a.jsAttributes[t]:(0,i.x1)(e,{...a,jsAttributes:{...a.jsAttributes,[t]:r}}),I(A,n,!0,o||null===r?"session":void 0)(t,r)}function O(){}g.log=function(e,{customAttributes:t={},level:r=y.p_.INFO}={}){(0,a.p)(f.xV,["API/log/called"],void 0,n.K7.metrics,R),(0,w.R)(R,e,t,r)},g.wrapLogger=(e,t,{customAttributes:r={},level:i=y.p_.INFO}={})=>{(0,a.p)(f.xV,["API/wrapLogger/called"],void 0,n.K7.metrics,R),T(R,e,t,{customAttributes:r,level:i})},m.forEach((e=>{g[e]=I(A,e,!0,"api")})),g.addPageAction=I(A,"addPageAction",!0,n.K7.genericEvents),g.setPageViewName=function(t,r){if("string"==typeof t)return"/"!==t.charAt(0)&&(t="/"+t),(0,o.f)(e).customTransaction=(r||"http://custom.transaction")+t,I(A,"setPageViewName",!0)()},g.setCustomAttribute=function(e,t,r=!1){if("string"==typeof e){if(["string","number","boolean"].includes(typeof t)||null===t)return N(e,t,"setCustomAttribute",r);(0,l.R)(40,typeof t)}else(0,l.R)(39,typeof e)},g.setUserId=function(e){if("string"==typeof e||null===e)return N("enduser.id",e,"setUserId",!0);(0,l.R)(41,typeof e)},g.setApplicationVersion=function(e){if("string"==typeof e||null===e)return N("application.version",e,"setApplicationVersion",!1);(0,l.R)(42,typeof e)},g.start=()=>{try{(0,a.p)(f.xV,["API/start/called"],void 0,n.K7.metrics,R),R.emit("manual-start-all")}catch(e){(0,l.R)(23,e)}},g[p.G4.RECORD]=function(){(0,a.p)(f.xV,["API/recordReplay/called"],void 0,n.K7.metrics,R),(0,a.p)(p.G4.RECORD,[],void 0,n.K7.sessionReplay,R)},g[p.G4.PAUSE]=function(){(0,a.p)(f.xV,["API/pauseReplay/called"],void 0,n.K7.metrics,R),(0,a.p)(p.G4.PAUSE,[],void 0,n.K7.sessionReplay,R)},g.interaction=function(e){return(new O).get("object"==typeof e?e:{})};const _=O.prototype={createTracer:function(e,t){var r={},i=this,o="function"==typeof t;return(0,a.p)(f.xV,["API/createTracer/called"],void 0,n.K7.metrics,R),h||(0,a.p)(S+"tracer",[(0,v.t)(),e,r],i,n.K7.spa,R),function(){if(x.emit((o?"":"no-")+"fn-start",[(0,v.t)(),i,o],r),o)try{return t.apply(this,arguments)}catch(e){const t="string"==typeof e?new Error(e):e;throw x.emit("fn-err",[arguments,this,t],r),t}finally{x.emit("fn-end",[(0,v.t)()],r)}}}};function I(e,t,r,i){return function(){return(0,a.p)(f.xV,["API/"+t+"/called"],void 0,n.K7.metrics,R),i&&(0,a.p)(e+t,[(0,v.t)(),...arguments],r?null:this,i,R),r?void 0:this}}function j(){r.e(478).then(r.bind(r,8778)).then((({setAPI:t})=>{t(e),(0,c.Ze)(e,"api")})).catch((e=>{(0,l.R)(27,e),R.abort()}))}return["actionText","setName","setAttribute","save","ignore","onEnd","getContext","end","get"].forEach((e=>{_[e]=I(S,e,void 0,h?n.K7.softNav:n.K7.spa)})),g.setCurrentRouteName=h?I(S,"routeName",void 0,n.K7.softNav):I(A,"routeName",!0,n.K7.spa),g.noticeError=function(t,r){"string"==typeof t&&(t=new Error(t)),(0,a.p)(f.xV,["API/noticeError/called"],void 0,n.K7.metrics,R),(0,a.p)("err",[t,(0,v.t)(),!1,r,!!E[e]],void 0,n.K7.jserrors,R)},d.RI?(0,u.GG)((()=>j()),!0):j(),g}(e.agentIdentifier,R,e.runSoftNavOverSpa)),void 0===e.exposed&&(e.exposed=k),I=!0}},8374:(e,t,r)=>{r.nc=(()=>{try{return document?.currentScript?.nonce}catch(e){}return""})()},860:(e,t,r)=>{"use strict";r.d(t,{$J:()=>o,K7:()=>n,P3:()=>i});const n={ajax:"ajax",genericEvents:"generic_events",jserrors:"jserrors",logging:"logging",metrics:"metrics",pageAction:"page_action",pageViewEvent:"page_view_event",pageViewTiming:"page_view_timing",sessionReplay:"session_replay",sessionTrace:"session_trace",softNav:"soft_navigations",spa:"spa"},i={[n.pageViewEvent]:1,[n.pageViewTiming]:2,[n.metrics]:3,[n.jserrors]:4,[n.spa]:5,[n.ajax]:6,[n.sessionTrace]:7,[n.softNav]:8,[n.sessionReplay]:9,[n.logging]:10,[n.genericEvents]:11},o={[n.pageViewTiming]:"events",[n.ajax]:"events",[n.spa]:"events",[n.softNav]:"events",[n.metrics]:"jserrors",[n.jserrors]:"jserrors",[n.sessionTrace]:"browser/blobs",[n.sessionReplay]:"browser/blobs",[n.logging]:"browser/logs",[n.genericEvents]:"ins"}}},n={};function i(e){var t=n[e];if(void 0!==t)return t.exports;var o=n[e]={exports:{}};return r[e](o,o.exports,i),o.exports}i.m=r,i.d=(e,t)=>{for(var r in t)i.o(t,r)&&!i.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})},i.f={},i.e=e=>Promise.all(Object.keys(i.f).reduce(((t,r)=>(i.f[r](e,t),t)),[])),i.u=e=>({212:"nr-spa-compressor",249:"nr-spa-recorder",478:"nr-spa"}[e]+"-1.274.0.min.js"),i.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),e={},t="NRBA-1.274.0.PROD:",i.l=(r,n,o,a)=>{if(e[r])e[r].push(n);else{var s,c;if(void 0!==o)for(var u=document.getElementsByTagName("script"),d=0;d<u.length;d++){var l=u[d];if(l.getAttribute("src")==r||l.getAttribute("data-webpack")==t+o){s=l;break}}if(!s){c=!0;var f={478:"sha512-1vUqEfJPB8Pihje9mv5CfYgkitO1FWcS+UQb84DbXqP8oYctRv4/lzl/MzNLPlRhcY1WVDBGL20I8vm6s2VV7g==",249:"sha512-Y/BeZAh6VSTmUtUNmS5XdyKxL92s30Fyyj8xVW76HSPxcKItL4+x2+kGMZc8pMJnUpZDz1L4eftZQAJh3D8NnA==",212:"sha512-Gn2tQ3qog5Yhrx/gRutkSTYPp+7nkKFt4/mIXg99LxcNpMDAYJZDBYmAACdoHNM86+iq1F3cBcQotFNzjIX8bw=="};(s=document.createElement("script")).charset="utf-8",s.timeout=120,i.nc&&s.setAttribute("nonce",i.nc),s.setAttribute("data-webpack",t+o),s.src=r,0!==s.src.indexOf(window.location.origin+"/")&&(s.crossOrigin="anonymous"),f[a]&&(s.integrity=f[a])}e[r]=[n];var h=(t,n)=>{s.onerror=s.onload=null,clearTimeout(p);var i=e[r];if(delete e[r],s.parentNode&&s.parentNode.removeChild(s),i&&i.forEach((e=>e(n))),t)return t(n)},p=setTimeout(h.bind(null,void 0,{type:"timeout",target:s}),12e4);s.onerror=h.bind(null,s.onerror),s.onload=h.bind(null,s.onload),c&&document.head.appendChild(s)}},i.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})},i.p="https://js-agent.newrelic.com/",(()=>{var e={38:0,788:0};i.f.j=(t,r)=>{var n=i.o(e,t)?e[t]:void 0;if(0!==n)if(n)r.push(n[2]);else{var o=new Promise(((r,i)=>n=e[t]=[r,i]));r.push(n[2]=o);var a=i.p+i.u(t),s=new Error;i.l(a,(r=>{if(i.o(e,t)&&(0!==(n=e[t])&&(e[t]=void 0),n)){var o=r&&("load"===r.type?"missing":r.type),a=r&&r.target&&r.target.src;s.message="Loading chunk "+t+" failed.\n("+o+": "+a+")",s.name="ChunkLoadError",s.type=o,s.request=a,n[1](s)}}),"chunk-"+t,t)}};var t=(t,r)=>{var n,o,[a,s,c]=r,u=0;if(a.some((t=>0!==e[t]))){for(n in s)i.o(s,n)&&(i.m[n]=s[n]);if(c)c(i)}for(t&&t(r);u<a.length;u++)o=a[u],i.o(e,o)&&e[o]&&e[o][0](),e[o]=0},r=self["webpackChunk:NRBA-1.274.0.PROD"]=self["webpackChunk:NRBA-1.274.0.PROD"]||[];r.forEach(t.bind(null,0)),r.push=t.bind(null,r.push.bind(r))})(),(()=>{"use strict";i(8374);var e=i(944),t=i(6344),r=i(9566);class n{agentIdentifier;constructor(e=(0,r.LA)(16)){this.agentIdentifier=e}#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}addPageAction(e,t){return this.#e("addPageAction",e,t)}setPageViewName(e,t){return this.#e("setPageViewName",e,t)}setCustomAttribute(e,t,r){return this.#e("setCustomAttribute",e,t,r)}noticeError(e,t){return this.#e("noticeError",e,t)}setUserId(e){return this.#e("setUserId",e)}setApplicationVersion(e){return this.#e("setApplicationVersion",e)}setErrorHandler(e){return this.#e("setErrorHandler",e)}addRelease(e,t){return this.#e("addRelease",e,t)}log(e,t){return this.#e("log",e,t)}}class o extends n{#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}start(){return this.#e("start")}finished(e){return this.#e("finished",e)}recordReplay(){return this.#e(t.G4.RECORD)}pauseReplay(){return this.#e(t.G4.PAUSE)}addToTrace(e){return this.#e("addToTrace",e)}setCurrentRouteName(e){return this.#e("setCurrentRouteName",e)}interaction(){return this.#e("interaction")}wrapLogger(e,t,r){return this.#e("wrapLogger",e,t,r)}}var a=i(860),s=i(9417);const c=Object.values(a.K7);function u(e){const t={};return c.forEach((r=>{t[r]=function(e,t){return!0===(0,s.gD)(t,"".concat(e,".enabled"))}(r,e)})),t}var d=i(425);var l=i(1687),f=i(4234),h=i(5289),p=i(6154),g=i(5270),m=i(7767),v=i(6389);class b extends f.W{constructor(e,t,r=!0){super(e.agentIdentifier,t),this.auto=r,this.abortHandler=void 0,this.featAggregate=void 0,this.onAggregateImported=void 0,!1===e.init[this.featureName].autoStart&&(this.auto=!1),this.auto?(0,l.Ak)(e.agentIdentifier,t):this.ee.on("manual-start-all",(0,v.J)((()=>{(0,l.Ak)(e.agentIdentifier,this.featureName),this.auto=!0,this.importAggregator(e)})))}importAggregator(t,r={}){if(this.featAggregate||!this.auto)return;let n;this.onAggregateImported=new Promise((e=>{n=e}));const o=async()=>{let o;try{if((0,m.V)(this.agentIdentifier)){const{setupAgentSession:e}=await i.e(478).then(i.bind(i,6526));o=e(t)}}catch(t){(0,e.R)(20,t),this.ee.emit("internal-error",[t]),this.featureName===a.K7.sessionReplay&&this.abortHandler?.()}try{if(t.sharedAggregator)await t.sharedAggregator;else{t.sharedAggregator=i.e(478).then(i.bind(i,9337));const{EventAggregator:e}=await t.sharedAggregator;t.sharedAggregator=new e}if(!this.#t(this.featureName,o))return(0,l.Ze)(this.agentIdentifier,this.featureName),void n(!1);const{lazyFeatureLoader:e}=await i.e(478).then(i.bind(i,6103)),{Aggregate:a}=await e(this.featureName,"aggregate");this.featAggregate=new a(t,r),n(!0)}catch(t){(0,e.R)(34,t),this.abortHandler?.(),(0,l.Ze)(this.agentIdentifier,this.featureName,!0),n(!1),this.ee&&this.ee.abort()}};p.RI?(0,h.GG)((()=>o()),!0):o()}#t(e,t){switch(e){case a.K7.sessionReplay:return(0,g.SR)(this.agentIdentifier)&&!!t;case a.K7.sessionTrace:return!!t;default:return!0}}}var y=i(6630);class w extends b{static featureName=y.T;constructor(e,t=!0){super(e,y.T,t),this.importAggregator(e)}}var R=i(384);var x=i(9908),T=i(2843),A=i(3878),E=i(782),S=i(1863);class N extends b{static featureName=E.T;constructor(e,t=!0){super(e,E.T,t),p.RI&&((0,T.u)((()=>(0,x.p)("docHidden",[(0,S.t)()],void 0,E.T,this.ee)),!0),(0,A.sp)("pagehide",(()=>(0,x.p)("winPagehide",[(0,S.t)()],void 0,E.T,this.ee))),this.importAggregator(e))}}var O=i(3969);class _ extends b{static featureName=O.TZ;constructor(e,t=!0){super(e,O.TZ,t),this.importAggregator(e)}}var I=i(6774),j=i(3304);class P{constructor(e,t,r,n,i){this.name="UncaughtError",this.message="string"==typeof e?e:(0,j.A)(e),this.sourceURL=t,this.line=r,this.column=n,this.__newrelic=i}}function C(e){return H(e)?e:new P(void 0!==e?.message?e.message:e,e?.filename||e?.sourceURL,e?.lineno||e?.line,e?.colno||e?.col,e?.__newrelic)}function k(e){const t="Unhandled Promise Rejection";if(!e?.reason)return;if(H(e.reason))try{return e.reason.message=t+": "+e.reason.message,C(e.reason)}catch(t){return C(e.reason)}const r=C(e.reason);return r.message=t+": "+r?.message,r}function L(e){if(e.error instanceof SyntaxError&&!/:\d+$/.test(e.error.stack?.trim())){const t=new P(e.message,e.filename,e.lineno,e.colno,e.error.__newrelic);return t.name=SyntaxError.name,t}return H(e.error)?e.error:C(e)}function H(e){return e instanceof Error&&!!e.stack}class D extends b{static featureName=I.T;#r=!1;constructor(e,r=!0){super(e,I.T,r);try{this.removeOnAbort=new AbortController}catch(e){}this.ee.on("internal-error",(e=>{this.abortHandler&&(0,x.p)("ierr",[C(e),(0,S.t)(),!0,{},this.#r],void 0,this.featureName,this.ee)})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.#r=e})),p.gm.addEventListener("unhandledrejection",(e=>{this.abortHandler&&(0,x.p)("err",[k(e),(0,S.t)(),!1,{unhandledPromiseRejection:1},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),p.gm.addEventListener("error",(e=>{this.abortHandler&&(0,x.p)("err",[L(e),(0,S.t)(),!1,{},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var M=i(8990);let K=1;const U="nr@id";function V(e){const t=typeof e;return!e||"object"!==t&&"function"!==t?-1:e===p.gm?0:(0,M.I)(e,U,(function(){return K++}))}function G(e){if("string"==typeof e&&e.length)return e.length;if("object"==typeof e){if("undefined"!=typeof ArrayBuffer&&e instanceof ArrayBuffer&&e.byteLength)return e.byteLength;if("undefined"!=typeof Blob&&e instanceof Blob&&e.size)return e.size;if(!("undefined"!=typeof FormData&&e instanceof FormData))try{return(0,j.A)(e).length}catch(e){return}}}var F=i(8139),B=i(7836),W=i(3434);const z={},q=["open","send"];function Z(t){var r=t||B.ee;const n=function(e){return(e||B.ee).get("xhr")}(r);if(z[n.debugId]++)return n;z[n.debugId]=1,(0,F.u)(r);var i=(0,W.YM)(n),o=p.gm.XMLHttpRequest,a=p.gm.MutationObserver,s=p.gm.Promise,c=p.gm.setInterval,u="readystatechange",d=["onload","onerror","onabort","onloadstart","onloadend","onprogress","ontimeout"],l=[],f=p.gm.XMLHttpRequest=function(t){const r=new o(t),a=n.context(r);try{n.emit("new-xhr",[r],a),r.addEventListener(u,(s=a,function(){var e=this;e.readyState>3&&!s.resolved&&(s.resolved=!0,n.emit("xhr-resolved",[],e)),i.inPlace(e,d,"fn-",y)}),(0,A.jT)(!1))}catch(t){(0,e.R)(15,t);try{n.emit("internal-error",[t])}catch(e){}}var s;return r};function h(e,t){i.inPlace(t,["onreadystatechange"],"fn-",y)}if(function(e,t){for(var r in e)t[r]=e[r]}(o,f),f.prototype=o.prototype,i.inPlace(f.prototype,q,"-xhr-",y),n.on("send-xhr-start",(function(e,t){h(e,t),function(e){l.push(e),a&&(g?g.then(b):c?c(b):(m=-m,v.data=m))}(t)})),n.on("open-xhr-start",h),a){var g=s&&s.resolve();if(!c&&!s){var m=1,v=document.createTextNode(m);new a(b).observe(v,{characterData:!0})}}else r.on("fn-end",(function(e){e[0]&&e[0].type===u||b()}));function b(){for(var e=0;e<l.length;e++)h(0,l[e]);l.length&&(l=[])}function y(e,t){return t}return n}var Y="fetch-",X=Y+"body-",J=["arrayBuffer","blob","json","text","formData"],Q=p.gm.Request,ee=p.gm.Response,te="prototype";const re={};function ne(e){const t=function(e){return(e||B.ee).get("fetch")}(e);if(!(Q&&ee&&p.gm.fetch))return t;if(re[t.debugId]++)return t;function r(e,r,n){var i=e[r];"function"==typeof i&&(e[r]=function(){var e,r=[...arguments],o={};t.emit(n+"before-start",[r],o),o[B.P]&&o[B.P].dt&&(e=o[B.P].dt);var a=i.apply(this,r);return t.emit(n+"start",[r,e],a),a.then((function(e){return t.emit(n+"end",[null,e],a),e}),(function(e){throw t.emit(n+"end",[e],a),e}))})}return re[t.debugId]=1,J.forEach((e=>{r(Q[te],e,X),r(ee[te],e,X)})),r(p.gm,"fetch",Y),t.on(Y+"end",(function(e,r){var n=this;if(r){var i=r.headers.get("content-length");null!==i&&(n.rxSize=i),t.emit(Y+"done",[null,r],n)}else t.emit(Y+"done",[e],n)})),t}var ie=i(7485),oe=i(5603);class ae{constructor(e){this.agentIdentifier=e}generateTracePayload(e){if(!this.shouldGenerateTrace(e))return null;var t=(0,oe.o)(this.agentIdentifier);if(!t)return null;var n=(t.accountID||"").toString()||null,i=(t.agentID||"").toString()||null,o=(t.trustKey||"").toString()||null;if(!n||!i)return null;var a=(0,r.ZF)(),s=(0,r.el)(),c=Date.now(),u={spanId:a,traceId:s,timestamp:c};return(e.sameOrigin||this.isAllowedOrigin(e)&&this.useTraceContextHeadersForCors())&&(u.traceContextParentHeader=this.generateTraceContextParentHeader(a,s),u.traceContextStateHeader=this.generateTraceContextStateHeader(a,c,n,i,o)),(e.sameOrigin&&!this.excludeNewrelicHeader()||!e.sameOrigin&&this.isAllowedOrigin(e)&&this.useNewrelicHeaderForCors())&&(u.newrelicHeader=this.generateTraceHeader(a,s,c,n,i,o)),u}generateTraceContextParentHeader(e,t){return"00-"+t+"-"+e+"-01"}generateTraceContextStateHeader(e,t,r,n,i){return i+"@nr=0-1-"+r+"-"+n+"-"+e+"----"+t}generateTraceHeader(e,t,r,n,i,o){if(!("function"==typeof p.gm?.btoa))return null;var a={v:[0,1],d:{ty:"Browser",ac:n,ap:i,id:e,tr:t,ti:r}};return o&&n!==o&&(a.d.tk=o),btoa((0,j.A)(a))}shouldGenerateTrace(e){return this.isDtEnabled()&&this.isAllowedOrigin(e)}isAllowedOrigin(e){var t=!1,r={};if((0,s.gD)(this.agentIdentifier,"distributed_tracing")&&(r=(0,s.D0)(this.agentIdentifier).distributed_tracing),e.sameOrigin)t=!0;else if(r.allowed_origins instanceof Array)for(var n=0;n<r.allowed_origins.length;n++){var i=(0,ie.D)(r.allowed_origins[n]);if(e.hostname===i.hostname&&e.protocol===i.protocol&&e.port===i.port){t=!0;break}}return t}isDtEnabled(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.enabled}excludeNewrelicHeader(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.exclude_newrelic_header}useNewrelicHeaderForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!1!==e.cors_use_newrelic_header}useTraceContextHeadersForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.cors_use_tracecontext_headers}}var se=i(9300),ce=i(7295),ue=["load","error","abort","timeout"],de=ue.length,le=(0,R.dV)().o.REQ,fe=(0,R.dV)().o.XHR;class he extends b{static featureName=se.T;constructor(e,t=!0){super(e,se.T,t),this.dt=new ae(e.agentIdentifier),this.handler=(e,t,r,n)=>(0,x.p)(e,t,r,n,this.ee);try{const e={xmlhttprequest:"xhr",fetch:"fetch",beacon:"beacon"};p.gm?.performance?.getEntriesByType("resource").forEach((t=>{if(t.initiatorType in e&&0!==t.responseStatus){const r={status:t.responseStatus},n={rxSize:t.transferSize,duration:Math.floor(t.duration),cbTime:0};pe(r,t.name),this.handler("xhr",[r,n,t.startTime,t.responseEnd,e[t.initiatorType]],void 0,a.K7.ajax)}}))}catch(e){}ne(this.ee),Z(this.ee),function(e,t,r,n){function i(e){var t=this;t.totalCbs=0,t.called=0,t.cbTime=0,t.end=R,t.ended=!1,t.xhrGuids={},t.lastSize=null,t.loadCaptureCalled=!1,t.params=this.params||{},t.metrics=this.metrics||{},e.addEventListener("load",(function(r){T(t,e)}),(0,A.jT)(!1)),p.lR||e.addEventListener("progress",(function(e){t.lastSize=e.loaded}),(0,A.jT)(!1))}function o(e){this.params={method:e[0]},pe(this,e[1]),this.metrics={}}function s(t,r){e.loader_config.xpid&&this.sameOrigin&&r.setRequestHeader("X-NewRelic-ID",e.loader_config.xpid);var i=n.generateTracePayload(this.parsedOrigin);if(i){var o=!1;i.newrelicHeader&&(r.setRequestHeader("newrelic",i.newrelicHeader),o=!0),i.traceContextParentHeader&&(r.setRequestHeader("traceparent",i.traceContextParentHeader),i.traceContextStateHeader&&r.setRequestHeader("tracestate",i.traceContextStateHeader),o=!0),o&&(this.dt=i)}}function c(e,r){var n=this.metrics,i=e[0],o=this;if(n&&i){var a=G(i);a&&(n.txSize=a)}this.startTime=(0,S.t)(),this.body=i,this.listener=function(e){try{"abort"!==e.type||o.loadCaptureCalled||(o.params.aborted=!0),("load"!==e.type||o.called===o.totalCbs&&(o.onloadCalled||"function"!=typeof r.onload)&&"function"==typeof o.end)&&o.end(r)}catch(e){try{t.emit("internal-error",[e])}catch(e){}}};for(var s=0;s<de;s++)r.addEventListener(ue[s],this.listener,(0,A.jT)(!1))}function u(e,t,r){this.cbTime+=e,t?this.onloadCalled=!0:this.called+=1,this.called!==this.totalCbs||!this.onloadCalled&&"function"==typeof r.onload||"function"!=typeof this.end||this.end(r)}function d(e,t){var r=""+V(e)+!!t;this.xhrGuids&&!this.xhrGuids[r]&&(this.xhrGuids[r]=!0,this.totalCbs+=1)}function l(e,t){var r=""+V(e)+!!t;this.xhrGuids&&this.xhrGuids[r]&&(delete this.xhrGuids[r],this.totalCbs-=1)}function f(){this.endTime=(0,S.t)()}function h(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-added",[e[1],e[2]],r)}function g(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-removed",[e[1],e[2]],r)}function m(e,t,r){t instanceof fe&&("onload"===r&&(this.onload=!0),("load"===(e[0]&&e[0].type)||this.onload)&&(this.xhrCbStart=(0,S.t)()))}function v(e,r){this.xhrCbStart&&t.emit("xhr-cb-time",[(0,S.t)()-this.xhrCbStart,this.onload,r],r)}function b(e){var t,r=e[1]||{};if("string"==typeof e[0]?0===(t=e[0]).length&&p.RI&&(t=""+p.gm.location.href):e[0]&&e[0].url?t=e[0].url:p.gm?.URL&&e[0]&&e[0]instanceof URL?t=e[0].href:"function"==typeof e[0].toString&&(t=e[0].toString()),"string"==typeof t&&0!==t.length){t&&(this.parsedOrigin=(0,ie.D)(t),this.sameOrigin=this.parsedOrigin.sameOrigin);var i=n.generateTracePayload(this.parsedOrigin);if(i&&(i.newrelicHeader||i.traceContextParentHeader))if(e[0]&&e[0].headers)s(e[0].headers,i)&&(this.dt=i);else{var o={};for(var a in r)o[a]=r[a];o.headers=new Headers(r.headers||{}),s(o.headers,i)&&(this.dt=i),e.length>1?e[1]=o:e.push(o)}}function s(e,t){var r=!1;return t.newrelicHeader&&(e.set("newrelic",t.newrelicHeader),r=!0),t.traceContextParentHeader&&(e.set("traceparent",t.traceContextParentHeader),t.traceContextStateHeader&&e.set("tracestate",t.traceContextStateHeader),r=!0),r}}function y(e,t){this.params={},this.metrics={},this.startTime=(0,S.t)(),this.dt=t,e.length>=1&&(this.target=e[0]),e.length>=2&&(this.opts=e[1]);var r,n=this.opts||{},i=this.target;"string"==typeof i?r=i:"object"==typeof i&&i instanceof le?r=i.url:p.gm?.URL&&"object"==typeof i&&i instanceof URL&&(r=i.href),pe(this,r);var o=(""+(i&&i instanceof le&&i.method||n.method||"GET")).toUpperCase();this.params.method=o,this.body=n.body,this.txSize=G(n.body)||0}function w(e,t){if(this.endTime=(0,S.t)(),this.params||(this.params={}),(0,ce.iW)(this.params))return;let n;this.params.status=t?t.status:0,"string"==typeof this.rxSize&&this.rxSize.length>0&&(n=+this.rxSize);const i={txSize:this.txSize,rxSize:n,duration:(0,S.t)()-this.startTime};r("xhr",[this.params,i,this.startTime,this.endTime,"fetch"],this,a.K7.ajax)}function R(e){const t=this.params,n=this.metrics;if(!this.ended){this.ended=!0;for(let t=0;t<de;t++)e.removeEventListener(ue[t],this.listener,!1);t.aborted||(0,ce.iW)(t)||(n.duration=(0,S.t)()-this.startTime,this.loadCazptureCalled||4!==e.readyState?null==t.status&&(t.status=0):T(this,e),n.cbTime=this.cbTime,r("xhr",[t,n,this.startTime,this.endTime,"xhr"],this,a.K7.ajax))}}function T(e,r){e.params.status=r.status;var n=function(e,t){var r=e.responseType;return"json"===r&&null!==t?t:"arraybuffer"===r||"blob"===r||"json"===r?G(e.response):"text"===r||""===r||void 0===r?G(e.responseText):void 0}(r,e.lastSize);if(n&&(e.metrics.rxSize=n),e.sameOrigin){var i=r.getResponseHeader("X-NewRelic-App-Data");i&&((0,x.p)(O.rs,["Ajax/CrossApplicationTracing/Header/Seen"],void 0,a.K7.metrics,t),e.params.cat=i.split(", ").pop())}e.loadCaptureCalled=!0}t.on("new-xhr",i),t.on("open-xhr-start",o),t.on("open-xhr-end",s),t.on("send-xhr-start",c),t.on("xhr-cb-time",u),t.on("xhr-load-added",d),t.on("xhr-load-removed",l),t.on("xhr-resolved",f),t.on("addEventListener-end",h),t.on("removeEventListener-end",g),t.on("fn-end",v),t.on("fetch-before-start",b),t.on("fetch-start",y),t.on("fn-start",m),t.on("fetch-done",w)}(e,this.ee,this.handler,this.dt),this.importAggregator(e)}}function pe(e,t){var r=(0,ie.D)(t),n=e.params||e;n.hostname=r.hostname,n.port=r.port,n.protocol=r.protocol,n.host=r.hostname+":"+r.port,n.pathname=r.pathname,e.parsedOrigin=r,e.sameOrigin=r.sameOrigin}const ge={},me=["pushState","replaceState"];function ve(e){const t=function(e){return(e||B.ee).get("history")}(e);return!p.RI||ge[t.debugId]++||(ge[t.debugId]=1,(0,W.YM)(t).inPlace(window.history,me,"-")),t}var be=i(3738);const{He:ye,bD:we,d3:Re,Kp:xe,TZ:Te,Lc:Ae,uP:Ee,Rz:Se}=be;class Ne extends b{static featureName=Te;constructor(e,t=!0){super(e,Te,t);if(!(0,m.V)(this.agentIdentifier))return void this.deregisterDrain();const r=this.ee;let n;ve(r),this.eventsEE=(0,F.u)(r),this.eventsEE.on(Ee,(function(e,t){this.bstStart=(0,S.t)()})),this.eventsEE.on(Ae,(function(e,t){(0,x.p)("bst",[e[0],t,this.bstStart,(0,S.t)()],void 0,a.K7.sessionTrace,r)})),r.on(Se+Re,(function(e){this.time=(0,S.t)(),this.startPath=location.pathname+location.hash})),r.on(Se+xe,(function(e){(0,x.p)("bstHist",[location.pathname+location.hash,this.startPath,this.time],void 0,a.K7.sessionTrace,r)}));try{n=new PerformanceObserver((e=>{const t=e.getEntries();(0,x.p)(ye,[t],void 0,a.K7.sessionTrace,r)})),n.observe({type:we,buffered:!0})}catch(e){}this.importAggregator(e,{resourceObserver:n})}}var Oe=i(2614);class _e extends b{static featureName=t.TZ;#i;#o;constructor(e,r=!0){let n;super(e,t.TZ,r),this.replayRunning=!1,this.#o=e;try{n=JSON.parse(localStorage.getItem("".concat(Oe.H3,"_").concat(Oe.uh)))}catch(e){}(0,g.SR)(e.agentIdentifier)&&this.ee.on(t.G4.RECORD,(()=>this.#a())),this.#s(n)?(this.#i=n?.sessionReplayMode,this.#c()):this.importAggregator(e),this.ee.on("err",(e=>{this.replayRunning&&(this.errorNoticed=!0,(0,x.p)(t.G4.ERROR_DURING_REPLAY,[e],void 0,this.featureName,this.ee))})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.replayRunning=e}))}#s(e){return e&&(e.sessionReplayMode===Oe.g.FULL||e.sessionReplayMode===Oe.g.ERROR)||(0,g.Aw)(this.agentIdentifier)}#u=!1;async#c(e){if(!this.#u){this.#u=!0;try{const{Recorder:t}=await Promise.all([i.e(478),i.e(249)]).then(i.bind(i,8589));this.recorder??=new t({mode:this.#i,agentIdentifier:this.agentIdentifier,trigger:e,ee:this.ee}),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording}catch(e){}this.importAggregator(this.#o,{recorder:this.recorder,errorNoticed:this.errorNoticed})}}#a(){this.featAggregate?this.featAggregate.mode!==Oe.g.FULL&&this.featAggregate.initializeRecording(Oe.g.FULL,!0):(this.#i=Oe.g.FULL,this.#c(t.Qb.API),this.recorder&&this.recorder.parent.mode!==Oe.g.FULL&&(this.recorder.parent.mode=Oe.g.FULL,this.recorder.stopRecording(),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording))}}var Ie=i(3962);class je extends b{static featureName=Ie.TZ;constructor(e,t=!0){if(super(e,Ie.TZ,t),!p.RI||!(0,R.dV)().o.MO)return;const r=ve(this.ee);Ie.tC.forEach((e=>{(0,A.sp)(e,(e=>{a(e)}),!0)}));const n=()=>(0,x.p)("newURL",[(0,S.t)(),""+window.location],void 0,this.featureName,this.ee);r.on("pushState-end",n),r.on("replaceState-end",n);try{this.removeOnAbort=new AbortController}catch(e){}(0,A.sp)("popstate",(e=>(0,x.p)("newURL",[e.timeStamp,""+window.location],void 0,this.featureName,this.ee)),!0,this.removeOnAbort?.signal);let i=!1;const o=new((0,R.dV)().o.MO)(((e,t)=>{i||(i=!0,requestAnimationFrame((()=>{(0,x.p)("newDom",[(0,S.t)()],void 0,this.featureName,this.ee),i=!1})))})),a=(0,v.s)((e=>{(0,x.p)("newUIEvent",[e],void 0,this.featureName,this.ee),o.observe(document.body,{attributes:!0,childList:!0,subtree:!0,characterData:!0})}),100,{leading:!0});this.abortHandler=function(){this.removeOnAbort?.abort(),o.disconnect(),this.abortHandler=void 0},this.importAggregator(e,{domObserver:o})}}var Pe=i(7378);const Ce={},ke=["appendChild","insertBefore","replaceChild"];function Le(e){const t=function(e){return(e||B.ee).get("jsonp")}(e);if(!p.RI||Ce[t.debugId])return t;Ce[t.debugId]=!0;var r=(0,W.YM)(t),n=/[?&](?:callback|cb)=([^&#]+)/,i=/(.*)\.([^.]+)/,o=/^(\w+)(\.|$)(.*)$/;function a(e,t){if(!e)return t;const r=e.match(o),n=r[1];return a(r[3],t[n])}return r.inPlace(Node.prototype,ke,"dom-"),t.on("dom-start",(function(e){!function(e){if(!e||"string"!=typeof e.nodeName||"script"!==e.nodeName.toLowerCase())return;if("function"!=typeof e.addEventListener)return;var o=(s=e.src,c=s.match(n),c?c[1]:null);var s,c;if(!o)return;var u=function(e){var t=e.match(i);if(t&&t.length>=3)return{key:t[2],parent:a(t[1],window)};return{key:e,parent:window}}(o);if("function"!=typeof u.parent[u.key])return;var d={};function l(){t.emit("jsonp-end",[],d),e.removeEventListener("load",l,(0,A.jT)(!1)),e.removeEventListener("error",f,(0,A.jT)(!1))}function f(){t.emit("jsonp-error",[],d),t.emit("jsonp-end",[],d),e.removeEventListener("load",l,(0,A.jT)(!1)),e.removeEventListener("error",f,(0,A.jT)(!1))}r.inPlace(u.parent,[u.key],"cb-",d),e.addEventListener("load",l,(0,A.jT)(!1)),e.addEventListener("error",f,(0,A.jT)(!1)),t.emit("new-jsonp",[e.src],d)}(e[0])})),t}const He={};function De(e){const t=function(e){return(e||B.ee).get("promise")}(e);if(He[t.debugId])return t;He[t.debugId]=!0;var r=t.context,n=(0,W.YM)(t),i=p.gm.Promise;return i&&function(){function e(r){var o=t.context(),a=n(r,"executor-",o,null,!1);const s=Reflect.construct(i,[a],e);return t.context(s).getCtx=function(){return o},s}p.gm.Promise=e,Object.defineProperty(e,"name",{value:"Promise"}),e.toString=function(){return i.toString()},Object.setPrototypeOf(e,i),["all","race"].forEach((function(r){const n=i[r];e[r]=function(e){let i=!1;[...e||[]].forEach((e=>{this.resolve(e).then(a("all"===r),a(!1))}));const o=n.apply(this,arguments);return o;function a(e){return function(){t.emit("propagate",[null,!i],o,!1,!1),i=i||!e}}}})),["resolve","reject"].forEach((function(r){const n=i[r];e[r]=function(e){const r=n.apply(this,arguments);return e!==r&&t.emit("propagate",[e,!0],r,!1,!1),r}})),e.prototype=i.prototype;const o=i.prototype.then;i.prototype.then=function(...e){var i=this,a=r(i);a.promise=i,e[0]=n(e[0],"cb-",a,null,!1),e[1]=n(e[1],"cb-",a,null,!1);const s=o.apply(this,e);return a.nextPromise=s,t.emit("propagate",[i,!0],s,!1,!1),s},i.prototype.then[W.Jt]=o,t.on("executor-start",(function(e){e[0]=n(e[0],"resolve-",this,null,!1),e[1]=n(e[1],"resolve-",this,null,!1)})),t.on("executor-err",(function(e,t,r){e[1](r)})),t.on("cb-end",(function(e,r,n){t.emit("propagate",[n,!0],this.nextPromise,!1,!1)})),t.on("propagate",(function(e,r,n){this.getCtx&&!r||(this.getCtx=function(){if(e instanceof Promise)var r=t.context(e);return r&&r.getCtx?r.getCtx():this})}))}(),t}const Me={},Ke="setTimeout",Ue="setInterval",Ve="clearTimeout",Ge="-start",Fe=[Ke,"setImmediate",Ue,Ve,"clearImmediate"];function Be(e){const t=function(e){return(e||B.ee).get("timer")}(e);if(Me[t.debugId]++)return t;Me[t.debugId]=1;var r=(0,W.YM)(t);return r.inPlace(p.gm,Fe.slice(0,2),Ke+"-"),r.inPlace(p.gm,Fe.slice(2,3),Ue+"-"),r.inPlace(p.gm,Fe.slice(3),Ve+"-"),t.on(Ue+Ge,(function(e,t,n){e[0]=r(e[0],"fn-",null,n)})),t.on(Ke+Ge,(function(e,t,n){this.method=n,this.timerDuration=isNaN(e[1])?0:+e[1],e[0]=r(e[0],"fn-",this,n)})),t}const We={};function ze(e){const t=function(e){return(e||B.ee).get("mutation")}(e);if(!p.RI||We[t.debugId])return t;We[t.debugId]=!0;var r=(0,W.YM)(t),n=p.gm.MutationObserver;return n&&(window.MutationObserver=function(e){return this instanceof n?new n(r(e,"fn-")):n.apply(this,arguments)},MutationObserver.prototype=n.prototype),t}const{TZ:qe,d3:Ze,Kp:Ye,$p:Xe,wW:Je,e5:Qe,tH:$e,uP:et,rw:tt,Lc:rt}=Pe;class nt extends b{static featureName=qe;constructor(e,t=!0){if(super(e,qe,t),!p.RI)return;try{this.removeOnAbort=new AbortController}catch(e){}let r,n=0;const i=this.ee.get("tracer"),o=Le(this.ee),a=De(this.ee),s=Be(this.ee),c=Z(this.ee),u=this.ee.get("events"),d=ne(this.ee),l=ve(this.ee),f=ze(this.ee);function h(e,t){l.emit("newURL",[""+window.location,t])}function g(){n++,r=window.location.hash,this[et]=(0,S.t)()}function m(){n--,window.location.hash!==r&&h(0,!0);var e=(0,S.t)();this[Qe]=~~this[Qe]+e-this[et],this[rt]=e}function v(e,t){e.on(t,(function(){this[t]=(0,S.t)()}))}this.ee.on(et,g),a.on(tt,g),o.on(tt,g),this.ee.on(rt,m),a.on(Je,m),o.on(Je,m),this.ee.on("fn-err",((...t)=>{t[2]?.__newrelic?.[e.agentIdentifier]||(0,x.p)("function-err",[...t],void 0,this.featureName,this.ee)})),this.ee.buffer([et,rt,"xhr-resolved"],this.featureName),u.buffer([et],this.featureName),s.buffer(["setTimeout"+Ye,"clearTimeout"+Ze,et],this.featureName),c.buffer([et,"new-xhr","send-xhr"+Ze],this.featureName),d.buffer([$e+Ze,$e+"-done",$e+Xe+Ze,$e+Xe+Ye],this.featureName),l.buffer(["newURL"],this.featureName),f.buffer([et],this.featureName),a.buffer(["propagate",tt,Je,"executor-err","resolve"+Ze],this.featureName),i.buffer([et,"no-"+et],this.featureName),o.buffer(["new-jsonp","cb-start","jsonp-error","jsonp-end"],this.featureName),v(d,$e+Ze),v(d,$e+"-done"),v(o,"new-jsonp"),v(o,"jsonp-end"),v(o,"cb-start"),l.on("pushState-end",h),l.on("replaceState-end",h),window.addEventListener("hashchange",h,(0,A.jT)(!0,this.removeOnAbort?.signal)),window.addEventListener("load",h,(0,A.jT)(!0,this.removeOnAbort?.signal)),window.addEventListener("popstate",(function(){h(0,n>1)}),(0,A.jT)(!0,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var it=i(3333);class ot extends b{static featureName=it.TZ;constructor(e,t=!0){super(e,it.TZ,t);const r=[e.init.page_action.enabled,e.init.performance.capture_marks,e.init.performance.capture_measures,e.init.user_actions.enabled];p.RI&&e.init.user_actions.enabled&&(it.Zp.forEach((e=>(0,A.sp)(e,(e=>(0,x.p)("ua",[e],void 0,this.featureName,this.ee)),!0))),it.qN.forEach((e=>(0,A.sp)(e,(e=>(0,x.p)("ua",[e],void 0,this.featureName,this.ee)))))),r.some((e=>e))?this.importAggregator(e):this.deregisterDrain()}}var at=i(993),st=i(3785);class ct extends b{static featureName=at.TZ;constructor(e,t=!0){super(e,at.TZ,t);const r=this.ee;this.ee.on("wrap-logger-end",(function([e]){const{level:t,customAttributes:n}=this;(0,st.R)(r,e,n,t)})),this.importAggregator(e)}}new class extends o{constructor(t,r){super(r),p.gm?(this.features={},(0,R.bQ)(this.agentIdentifier,this),this.desiredFeatures=new Set(t.features||[]),this.desiredFeatures.add(w),this.runSoftNavOverSpa=[...this.desiredFeatures].some((e=>e.featureName===a.K7.softNav)),(0,d.j)(this,t,t.loaderType||"agent"),this.run()):(0,e.R)(21)}get config(){return{info:this.info,init:this.init,loader_config:this.loader_config,runtime:this.runtime}}run(){try{const t=u(this.agentIdentifier),r=[...this.desiredFeatures];r.sort(((e,t)=>a.P3[e.featureName]-a.P3[t.featureName])),r.forEach((r=>{if(!t[r.featureName]&&r.featureName!==a.K7.pageViewEvent)return;if(this.runSoftNavOverSpa&&r.featureName===a.K7.spa)return;if(!this.runSoftNavOverSpa&&r.featureName===a.K7.softNav)return;const n=function(e){switch(e){case a.K7.ajax:return[a.K7.jserrors];case a.K7.sessionTrace:return[a.K7.ajax,a.K7.pageViewEvent];case a.K7.sessionReplay:return[a.K7.sessionTrace];case a.K7.pageViewTiming:return[a.K7.pageViewEvent];default:return[]}}(r.featureName).filter((e=>!(e in this.features)));n.length>0&&(0,e.R)(36,{targetFeature:r.featureName,missingDependencies:n}),this.features[r.featureName]=new r(this)}))}catch(t){(0,e.R)(22,t);for(const e in this.features)this.features[e].abortHandler?.();const r=(0,R.Zm)();delete r.initializedAgents[this.agentIdentifier]?.api,delete r.initializedAgents[this.agentIdentifier]?.features,delete this.sharedAggregator;return r.ee.get(this.agentIdentifier).abort(),!1}}}({features:[he,w,N,Ne,_e,_,D,ot,ct,je,nt],loaderType:"spa"})})()})();</script> <meta name="viewport" content="width=device-width, initial-scale=1" /> <link rel="preload" href="https://www.nobelprize.org/wp-content/themes/nobelprize/assets/fonts/ivar/AlfredSerifText-Regular.woff2" as="font" type="font/woff2" crossorigin="anonymous"> <link rel="preload" href="https://www.nobelprize.org/wp-content/themes/nobelprize/assets/fonts/alfred/AlfredSans-Regular.woff2" as="font" type="font/woff2" crossorigin="anonymous"> <link rel="profile" href="http://gmpg.org/xfn/11"> <script>(function(html){html.className = html.className.replace(/\bno-js\b/,'js')})(document.documentElement);</script> <meta name='robots' content='index, follow, max-image-preview:large, max-snippet:-1, max-video-preview:-1' /> <!-- This site is optimized with the Yoast SEO plugin v23.2 - https://yoast.com/wordpress/plugins/seo/ --> <title>The Nobel Prize in Physiology or Medicine 1967 - NobelPrize.org</title> <meta property="og:locale" content="en_US" /> <meta property="og:type" content="website" /> <meta property="og:site_name" content="NobelPrize.org" /> <meta name="twitter:card" content="summary_large_image" /> <script type="application/ld+json" class="yoast-schema-graph">{"@context":"https://schema.org","@graph":[{"@type":"WebSite","@id":"https://www.nobelprize.org/#website","url":"https://www.nobelprize.org/","name":"NobelPrize.org","description":"The official website of the Nobel Prize","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://www.nobelprize.org/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"}]}</script> <!-- / Yoast SEO plugin. --> <link rel='dns-prefetch' href='//www.nobelprize.org' /> <link rel='dns-prefetch' href='//stats.wp.com' /> <link rel='stylesheet' id='mediaelement-css' href='https://www.nobelprize.org/wp-includes/js/mediaelement/mediaelementplayer-legacy.min.css?ver=4.2.17' type='text/css' media='all' /> <link rel='stylesheet' id='wp-mediaelement-css' href='https://www.nobelprize.org/wp-includes/js/mediaelement/wp-mediaelement.min.css?ver=6.6.2' type='text/css' media='all' /> <style id='jetpack-sharing-buttons-style-inline-css' type='text/css'> .jetpack-sharing-buttons__services-list{display:flex;flex-direction:row;flex-wrap:wrap;gap:0;list-style-type:none;margin:5px;padding:0}.jetpack-sharing-buttons__services-list.has-small-icon-size{font-size:12px}.jetpack-sharing-buttons__services-list.has-normal-icon-size{font-size:16px}.jetpack-sharing-buttons__services-list.has-large-icon-size{font-size:24px}.jetpack-sharing-buttons__services-list.has-huge-icon-size{font-size:36px}@media print{.jetpack-sharing-buttons__services-list{display:none!important}}.editor-styles-wrapper .wp-block-jetpack-sharing-buttons{gap:0;padding-inline-start:0}ul.jetpack-sharing-buttons__services-list.has-background{padding:1.25em 2.375em} </style> <style id='global-styles-inline-css' type='text/css'> :root{--wp--preset--aspect-ratio--square: 1;--wp--preset--aspect-ratio--4-3: 4/3;--wp--preset--aspect-ratio--3-4: 3/4;--wp--preset--aspect-ratio--3-2: 3/2;--wp--preset--aspect-ratio--2-3: 2/3;--wp--preset--aspect-ratio--16-9: 16/9;--wp--preset--aspect-ratio--9-16: 9/16;--wp--preset--color--black: #2e2a25;--wp--preset--color--cyan-bluish-gray: #abb8c3;--wp--preset--color--white: #ffffff;--wp--preset--color--pale-pink: #f78da7;--wp--preset--color--vivid-red: #cf2e2e;--wp--preset--color--luminous-vivid-orange: #ff6900;--wp--preset--color--luminous-vivid-amber: #fcb900;--wp--preset--color--light-green-cyan: #7bdcb5;--wp--preset--color--vivid-green-cyan: #00d084;--wp--preset--color--pale-cyan-blue: #8ed1fc;--wp--preset--color--vivid-cyan-blue: #0693e3;--wp--preset--color--vivid-purple: #9b51e0;--wp--preset--color--black-400: #969492;--wp--preset--color--grey-500: #8a8a8d;--wp--preset--color--grey-400: #c8c8c8;--wp--preset--color--grey-100: #f1f1f1;--wp--preset--color--nobel-gold: #cc9b40;--wp--preset--color--nobel-pale: #f2f0ee;--wp--preset--color--nobel-smoke: #f9f5ed;--wp--preset--color--blue-700: #004b87;--wp--preset--color--blue-500: #3880c3;--wp--preset--color--blue-400: #a0c5d8;--wp--preset--color--blue-300: #c2ced9;--wp--preset--color--blue-100: #ebf2f8;--wp--preset--color--red: #bc1836;--wp--preset--color--green-100: #eaefed;--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple: linear-gradient(135deg,rgba(6,147,227,1) 0%,rgb(155,81,224) 100%);--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan: linear-gradient(135deg,rgb(122,220,180) 0%,rgb(0,208,130) 100%);--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange: linear-gradient(135deg,rgba(252,185,0,1) 0%,rgba(255,105,0,1) 100%);--wp--preset--gradient--luminous-vivid-orange-to-vivid-red: linear-gradient(135deg,rgba(255,105,0,1) 0%,rgb(207,46,46) 100%);--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray: linear-gradient(135deg,rgb(238,238,238) 0%,rgb(169,184,195) 100%);--wp--preset--gradient--cool-to-warm-spectrum: linear-gradient(135deg,rgb(74,234,220) 0%,rgb(151,120,209) 20%,rgb(207,42,186) 40%,rgb(238,44,130) 60%,rgb(251,105,98) 80%,rgb(254,248,76) 100%);--wp--preset--gradient--blush-light-purple: linear-gradient(135deg,rgb(255,206,236) 0%,rgb(152,150,240) 100%);--wp--preset--gradient--blush-bordeaux: linear-gradient(135deg,rgb(254,205,165) 0%,rgb(254,45,45) 50%,rgb(107,0,62) 100%);--wp--preset--gradient--luminous-dusk: linear-gradient(135deg,rgb(255,203,112) 0%,rgb(199,81,192) 50%,rgb(65,88,208) 100%);--wp--preset--gradient--pale-ocean: linear-gradient(135deg,rgb(255,245,203) 0%,rgb(182,227,212) 50%,rgb(51,167,181) 100%);--wp--preset--gradient--electric-grass: linear-gradient(135deg,rgb(202,248,128) 0%,rgb(113,206,126) 100%);--wp--preset--gradient--midnight: linear-gradient(135deg,rgb(2,3,129) 0%,rgb(40,116,252) 100%);--wp--preset--font-size--small: 13px;--wp--preset--font-size--medium: clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.682), 20px);--wp--preset--font-size--large: clamp(22.041px, 1.378rem + ((1vw - 3.2px) * 1.586), 36px);--wp--preset--font-size--x-large: clamp(25.014px, 1.563rem + ((1vw - 3.2px) * 1.93), 42px);--wp--preset--font-size--14: 0.875rem;--wp--preset--font-size--15: clamp(0.875rem, 0.875rem + ((1vw - 0.2rem) * 0.115), 0.938rem);--wp--preset--font-size--16: clamp(0.875rem, 0.875rem + ((1vw - 0.2rem) * 0.227), 1rem);--wp--preset--font-size--18: clamp(0.875rem, 0.875rem + ((1vw - 0.2rem) * 0.455), 1.125rem);--wp--preset--font-size--22: clamp(0.915rem, 0.915rem + ((1vw - 0.2rem) * 0.836), 1.375rem);--wp--preset--font-size--24: clamp(0.984rem, 0.984rem + ((1vw - 0.2rem) * 0.938), 1.5rem);--wp--preset--font-size--32: clamp(1.5rem, 1.5rem + ((1vw - 0.2rem) * 0.909), 2rem);--wp--preset--font-size--48: clamp(2rem, 2rem + ((1vw - 0.2rem) * 1.818), 3rem);--wp--preset--font-size--100: clamp(4rem, 4rem + ((1vw - 0.2rem) * 4.091), 6.25rem);--wp--preset--font-family--primary: 'Alfred Sans Regular', 'Helvetica Neue', 'Arial', sans-serif;--wp--preset--font-family--secondary: 'Alfred Serif Regular', 'Times', 'Times New Roman', serif;--wp--preset--spacing--20: 0.5rem;--wp--preset--spacing--30: 1rem;--wp--preset--spacing--40: 1.25rem;--wp--preset--spacing--50: 1.5rem;--wp--preset--spacing--60: 2rem;--wp--preset--spacing--70: 2.5rem;--wp--preset--spacing--80: 3rem;--wp--preset--spacing--10: 0.25rem;--wp--preset--spacing--90: 3.5rem;--wp--preset--spacing--100: 4rem;--wp--preset--spacing--110: 4.5rem;--wp--preset--spacing--120: 5rem;--wp--preset--spacing--130: 5.5rem;--wp--preset--spacing--140: 6rem;--wp--preset--spacing--150: 6.5rem;--wp--preset--spacing--160: 7rem;--wp--preset--shadow--natural: 6px 6px 9px rgba(0, 0, 0, 0.2);--wp--preset--shadow--deep: 12px 12px 50px rgba(0, 0, 0, 0.4);--wp--preset--shadow--sharp: 6px 6px 0px rgba(0, 0, 0, 0.2);--wp--preset--shadow--outlined: 6px 6px 0px -3px rgba(255, 255, 255, 1), 6px 6px rgba(0, 0, 0, 1);--wp--preset--shadow--crisp: 6px 6px 0px rgba(0, 0, 0, 1);--wp--custom--image-ratio--regular: 3/2;--wp--custom--image-ratio--landscape: 16/9;--wp--custom--image-ratio--portrait: 2/3;--wp--custom--line-height--xs: 1;--wp--custom--line-height--s: 1.125;--wp--custom--line-height--sm: 1.25;--wp--custom--line-height--m: 1.3;--wp--custom--line-height--l: 1.4;--wp--custom--line-height--xl: 1.5;--wp--custom--font-variant--heading--1--font-size: var(--wp--preset--font-size--48);--wp--custom--font-variant--heading--1--line-height: var(--wp--custom--line-height--xs);--wp--custom--font-variant--heading--1--font-family: var(--wp--preset--font-family--primary);--wp--custom--font-variant--heading--2--font-size: var(--wp--preset--font-size--32);--wp--custom--font-variant--heading--2--line-height: var(--wp--custom--line-height--s);--wp--custom--font-variant--heading--2--font-family: var(--wp--preset--font-family--primary);--wp--custom--font-variant--heading--3--font-size: var(--wp--preset--font-size--24);--wp--custom--font-variant--heading--3--line-height: var(--wp--custom--line-height--s);--wp--custom--font-variant--heading--3--font-family: var(--wp--preset--font-family--primary);--wp--custom--font-variant--heading--4--font-size: var(--wp--preset--font-size--18);--wp--custom--font-variant--heading--4--line-height: var(--wp--custom--line-height--sm);--wp--custom--font-variant--heading--4--font-family: var(--wp--preset--font-family--primary);--wp--custom--font-variant--heading--5--font-size: var(--wp--preset--font-size--16);--wp--custom--font-variant--heading--5--line-height: var(--wp--custom--line-height--m);--wp--custom--font-variant--heading--5--font-family: var(--wp--preset--font-family--primary);--wp--custom--font-variant--heading--6--font-size: var(--wp--preset--font-size--15);--wp--custom--font-variant--heading--6--line-height: var(--wp--custom--line-height--xl);--wp--custom--font-variant--heading--6--font-family: var(--wp--preset--font-family--primary);--wp--custom--font-variant--paragraph--xsmall--font-size: var(--wp--preset--font-size--14);--wp--custom--font-variant--paragraph--xsmall--line-height: var(--wp--custom--line-height--l);--wp--custom--font-variant--paragraph--xsmall--font-family: var(--wp--preset--font-family--secondary);--wp--custom--font-variant--paragraph--small--font-size: var(--wp--preset--font-size--16);--wp--custom--font-variant--paragraph--small--line-height: var(--wp--custom--line-height--l);--wp--custom--font-variant--paragraph--small--font-family: var(--wp--preset--font-family--secondary);--wp--custom--font-variant--paragraph--medium--font-size: var(--wp--preset--font-size--18);--wp--custom--font-variant--paragraph--medium--line-height: var(--wp--custom--line-height--m);--wp--custom--font-variant--paragraph--medium--font-family: var(--wp--preset--font-family--secondary);--wp--custom--font-variant--paragraph--large--font-size: var(--wp--preset--font-size--22);--wp--custom--font-variant--paragraph--large--line-height: var(--wp--custom--line-height--m);--wp--custom--font-variant--paragraph--large--font-family: var(--wp--preset--font-family--secondary);--wp--custom--font-variant--button--small--font-size: var(--wp--preset--font-size--14);--wp--custom--font-variant--button--small--line-height: var(--wp--custom--line-height--sm);--wp--custom--font-variant--button--small--font-family: var(--wp--preset--font-family--primary);--wp--custom--font-variant--button--large--font-size: var(--wp--preset--font-size--16);--wp--custom--font-variant--button--large--line-height: var(--wp--custom--line-height--sm);--wp--custom--font-variant--button--large--font-family: var(--wp--preset--font-family--primary);--wp--custom--font-variant--info--counters--font-size: var(--wp--preset--font-size--100);--wp--custom--font-variant--info--counters--line-height: var(--wp--custom--line-height--xs);--wp--custom--font-variant--info--counters--font-family: var(--wp--preset--font-family--primary);--wp--custom--font-variant--info--legal--font-size: var(--wp--preset--font-size--14);--wp--custom--font-variant--info--legal--line-height: var(--wp--custom--line-height--l);--wp--custom--font-variant--info--legal--font-family: var(--wp--preset--font-family--primary);}.wp-block-nobel-prize-queried-content{--wp--preset--color--grey-100: #f1f1f1;--wp--preset--color--nobel-pale: #f2f0ee;--wp--preset--color--nobel-smoke: #f9f5ed;--wp--preset--color--blue-100: #ebf2f8;--wp--preset--color--green-100: #eaefed;}.has-black-color{color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-color{color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-color{color: var(--wp--preset--color--white) !important;}.has-pale-pink-color{color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-color{color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-color{color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-color{color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-color{color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-color{color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-color{color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-color{color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-color{color: var(--wp--preset--color--vivid-purple) !important;}.has-black-400-color{color: var(--wp--preset--color--black-400) !important;}.has-grey-500-color{color: var(--wp--preset--color--grey-500) !important;}.has-grey-400-color{color: var(--wp--preset--color--grey-400) !important;}.has-grey-100-color{color: var(--wp--preset--color--grey-100) !important;}.has-nobel-gold-color{color: var(--wp--preset--color--nobel-gold) !important;}.has-nobel-pale-color{color: var(--wp--preset--color--nobel-pale) !important;}.has-nobel-smoke-color{color: var(--wp--preset--color--nobel-smoke) !important;}.has-blue-700-color{color: var(--wp--preset--color--blue-700) !important;}.has-blue-500-color{color: var(--wp--preset--color--blue-500) !important;}.has-blue-400-color{color: var(--wp--preset--color--blue-400) !important;}.has-blue-300-color{color: var(--wp--preset--color--blue-300) !important;}.has-blue-100-color{color: var(--wp--preset--color--blue-100) !important;}.has-red-color{color: var(--wp--preset--color--red) !important;}.has-green-100-color{color: var(--wp--preset--color--green-100) !important;}.has-black-background-color{background-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-background-color{background-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-background-color{background-color: var(--wp--preset--color--white) !important;}.has-pale-pink-background-color{background-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-background-color{background-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-background-color{background-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-background-color{background-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-background-color{background-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-background-color{background-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-background-color{background-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-background-color{background-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-background-color{background-color: var(--wp--preset--color--vivid-purple) !important;}.has-black-400-background-color{background-color: var(--wp--preset--color--black-400) !important;}.has-grey-500-background-color{background-color: var(--wp--preset--color--grey-500) !important;}.has-grey-400-background-color{background-color: var(--wp--preset--color--grey-400) !important;}.has-grey-100-background-color{background-color: var(--wp--preset--color--grey-100) !important;}.has-nobel-gold-background-color{background-color: var(--wp--preset--color--nobel-gold) !important;}.has-nobel-pale-background-color{background-color: var(--wp--preset--color--nobel-pale) !important;}.has-nobel-smoke-background-color{background-color: var(--wp--preset--color--nobel-smoke) !important;}.has-blue-700-background-color{background-color: var(--wp--preset--color--blue-700) !important;}.has-blue-500-background-color{background-color: var(--wp--preset--color--blue-500) !important;}.has-blue-400-background-color{background-color: var(--wp--preset--color--blue-400) !important;}.has-blue-300-background-color{background-color: var(--wp--preset--color--blue-300) !important;}.has-blue-100-background-color{background-color: var(--wp--preset--color--blue-100) !important;}.has-red-background-color{background-color: var(--wp--preset--color--red) !important;}.has-green-100-background-color{background-color: var(--wp--preset--color--green-100) !important;}.has-black-border-color{border-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-border-color{border-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-border-color{border-color: var(--wp--preset--color--white) !important;}.has-pale-pink-border-color{border-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-border-color{border-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-border-color{border-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-border-color{border-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-border-color{border-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-border-color{border-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-border-color{border-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-border-color{border-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-border-color{border-color: var(--wp--preset--color--vivid-purple) !important;}.has-black-400-border-color{border-color: var(--wp--preset--color--black-400) !important;}.has-grey-500-border-color{border-color: var(--wp--preset--color--grey-500) !important;}.has-grey-400-border-color{border-color: var(--wp--preset--color--grey-400) !important;}.has-grey-100-border-color{border-color: var(--wp--preset--color--grey-100) !important;}.has-nobel-gold-border-color{border-color: var(--wp--preset--color--nobel-gold) !important;}.has-nobel-pale-border-color{border-color: var(--wp--preset--color--nobel-pale) !important;}.has-nobel-smoke-border-color{border-color: var(--wp--preset--color--nobel-smoke) !important;}.has-blue-700-border-color{border-color: var(--wp--preset--color--blue-700) !important;}.has-blue-500-border-color{border-color: var(--wp--preset--color--blue-500) !important;}.has-blue-400-border-color{border-color: var(--wp--preset--color--blue-400) !important;}.has-blue-300-border-color{border-color: var(--wp--preset--color--blue-300) !important;}.has-blue-100-border-color{border-color: var(--wp--preset--color--blue-100) !important;}.has-red-border-color{border-color: var(--wp--preset--color--red) !important;}.has-green-100-border-color{border-color: var(--wp--preset--color--green-100) !important;}.has-vivid-cyan-blue-to-vivid-purple-gradient-background{background: var(--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple) !important;}.has-light-green-cyan-to-vivid-green-cyan-gradient-background{background: var(--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan) !important;}.has-luminous-vivid-amber-to-luminous-vivid-orange-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange) !important;}.has-luminous-vivid-orange-to-vivid-red-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-orange-to-vivid-red) !important;}.has-very-light-gray-to-cyan-bluish-gray-gradient-background{background: var(--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray) !important;}.has-cool-to-warm-spectrum-gradient-background{background: var(--wp--preset--gradient--cool-to-warm-spectrum) !important;}.has-blush-light-purple-gradient-background{background: var(--wp--preset--gradient--blush-light-purple) !important;}.has-blush-bordeaux-gradient-background{background: var(--wp--preset--gradient--blush-bordeaux) !important;}.has-luminous-dusk-gradient-background{background: var(--wp--preset--gradient--luminous-dusk) !important;}.has-pale-ocean-gradient-background{background: var(--wp--preset--gradient--pale-ocean) !important;}.has-electric-grass-gradient-background{background: var(--wp--preset--gradient--electric-grass) !important;}.has-midnight-gradient-background{background: var(--wp--preset--gradient--midnight) !important;}.has-small-font-size{font-size: var(--wp--preset--font-size--small) !important;}.has-medium-font-size{font-size: var(--wp--preset--font-size--medium) !important;}.has-large-font-size{font-size: var(--wp--preset--font-size--large) !important;}.has-x-large-font-size{font-size: var(--wp--preset--font-size--x-large) !important;}.has-14-font-size{font-size: var(--wp--preset--font-size--14) !important;}.has-15-font-size{font-size: var(--wp--preset--font-size--15) !important;}.has-16-font-size{font-size: var(--wp--preset--font-size--16) !important;}.has-18-font-size{font-size: var(--wp--preset--font-size--18) !important;}.has-22-font-size{font-size: var(--wp--preset--font-size--22) !important;}.has-24-font-size{font-size: var(--wp--preset--font-size--24) !important;}.has-32-font-size{font-size: var(--wp--preset--font-size--32) !important;}.has-48-font-size{font-size: var(--wp--preset--font-size--48) !important;}.has-100-font-size{font-size: var(--wp--preset--font-size--100) !important;}.has-primary-font-family{font-family: var(--wp--preset--font-family--primary) !important;}.has-secondary-font-family{font-family: var(--wp--preset--font-family--secondary) !important;}.wp-block-nobel-prize-queried-content.has-grey-100-color{color: var(--wp--preset--color--grey-100) !important;}.wp-block-nobel-prize-queried-content.has-nobel-pale-color{color: var(--wp--preset--color--nobel-pale) !important;}.wp-block-nobel-prize-queried-content.has-nobel-smoke-color{color: var(--wp--preset--color--nobel-smoke) !important;}.wp-block-nobel-prize-queried-content.has-blue-100-color{color: var(--wp--preset--color--blue-100) !important;}.wp-block-nobel-prize-queried-content.has-green-100-color{color: var(--wp--preset--color--green-100) !important;}.wp-block-nobel-prize-queried-content.has-grey-100-background-color{background-color: var(--wp--preset--color--grey-100) !important;}.wp-block-nobel-prize-queried-content.has-nobel-pale-background-color{background-color: var(--wp--preset--color--nobel-pale) !important;}.wp-block-nobel-prize-queried-content.has-nobel-smoke-background-color{background-color: var(--wp--preset--color--nobel-smoke) !important;}.wp-block-nobel-prize-queried-content.has-blue-100-background-color{background-color: var(--wp--preset--color--blue-100) !important;}.wp-block-nobel-prize-queried-content.has-green-100-background-color{background-color: var(--wp--preset--color--green-100) !important;}.wp-block-nobel-prize-queried-content.has-grey-100-border-color{border-color: var(--wp--preset--color--grey-100) !important;}.wp-block-nobel-prize-queried-content.has-nobel-pale-border-color{border-color: var(--wp--preset--color--nobel-pale) !important;}.wp-block-nobel-prize-queried-content.has-nobel-smoke-border-color{border-color: var(--wp--preset--color--nobel-smoke) !important;}.wp-block-nobel-prize-queried-content.has-blue-100-border-color{border-color: var(--wp--preset--color--blue-100) !important;}.wp-block-nobel-prize-queried-content.has-green-100-border-color{border-color: var(--wp--preset--color--green-100) !important;} :where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;} :where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;} :root :where(.wp-block-pullquote){font-size: clamp(0.984em, 0.984rem + ((1vw - 0.2em) * 0.938), 1.5em);line-height: 1.6;} </style> <link rel='stylesheet' id='nobelprize_block_library_admin-css' href='https://www.nobelprize.org/wp-content/plugins/nobelprize-block-library/dist/css/frontend.css?ver=9af3caa4ba4635a79486' type='text/css' media='all' /> <link rel='stylesheet' id='styles-css' href='https://www.nobelprize.org/wp-content/themes/nobelprize/dist/css/frontend.css?ver=0fc4ea04d626abf846ed' type='text/css' media='all' /> <script type="text/javascript" id="loadjs-js-extra"> /* <![CDATA[ */ var fallback = {"path":"\/var\/www\/html\/wp-content\/themes\/nobelprize\/\/assets\/js\/frontend\/lib\/respimg\/ls.respimg.min.js"}; /* ]]> */ </script> <script type="text/javascript" src="https://www.nobelprize.org/wp-content/themes/nobelprize/assets/js/frontend/lib/loadjs.js?ver=1732293022" id="loadjs-js"></script> <style>img#wpstats{display:none}</style> <link type="text/plain" rel="author" href="https://www.nobelprize.org/wp-content/themes/nobelprize/humans.txt" /> <script> window.VIDEOJS_NO_BASE_THEME = true; window.VIDEOJS_NO_DYNAMIC_STYLE = true; </script> <!-- OneTrust Cookies Consent Notice start for www.nobelprize.org --> <script type="text/javascript" src="https://cdn.cookielaw.org/consent/d75760b8-7732-445e-9a87-2de3e237d0fe/OtAutoBlock.js"></script> <script src="https://cdn.cookielaw.org/scripttemplates/otSDKStub.js" type="text/javascript" charset="UTF-8" data-domain-script="d75760b8-7732-445e-9a87-2de3e237d0fe"></script> <script type="text/javascript"> function OptanonWrapper() { } </script> <!-- OneTrust Cookies Consent Notice end for www.nobelprize.org --> <!-- Google Tag Manager --> <script type="text/javascript">(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-WDHZ8W5');</script> <!-- End Google Tag Manager --> <!-- //start Title specific social meta tags --> <meta name="twitter:title" content="The Nobel Prize in Physiology or Medicine 1967"><!-- Twitter --> <meta itemprop="name" content="The Nobel Prize in Physiology or Medicine 1967" /><!-- Google+ --> <meta property="og:title" content="The Nobel Prize in Physiology or Medicine 1967" /><!-- OG --> <!-- //end Title specific social meta tags --> <!-- //start Description specific social meta tags --> <meta name="twitter:description" content="The Nobel Prize in Physiology or Medicine 1967 was awarded jointly to Ragnar Granit, Haldan Keffer Hartline and George Wald "for their discoveries concerning the primary physiological and chemical visual processes in the eye""><!-- Twitter --> <meta itemprop="description" content="The Nobel Prize in Physiology or Medicine 1967 was awarded jointly to Ragnar Granit, Haldan Keffer Hartline and George Wald "for their discoveries concerning the primary physiological and chemical visual processes in the eye"" /><!-- Google+ --> <meta property="og:description" content="The Nobel Prize in Physiology or Medicine 1967 was awarded jointly to Ragnar Granit, Haldan Keffer Hartline and George Wald "for their discoveries concerning the primary physiological and chemical visual processes in the eye"" /><!-- OG --> <!-- //end Description specific social meta tags --> <!-- //start Image specific social meta tags --> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:image" content="https://www.nobelprize.org/images/granit-13196-landscape-medium.jpg" /><!-- Twitter --> <meta itemprop="image" content="https://www.nobelprize.org/images/granit-13196-landscape-medium.jpg" /><!-- Google+ --> <meta property="og:image" content="https://www.nobelprize.org/images/granit-13196-landscape-medium.jpg" /><!-- OG --> <meta property="og:image" content="https://www.nobelprize.org/images/hartline-13197-landscape-medium.jpg" /><!-- OG --> <meta property="og:image" content="https://www.nobelprize.org/images/wald-13198-landscape-medium.jpg" /><!-- OG --> <!-- //end Image specific social meta tags --> <meta property="og:url" content="https://www.nobelprize.org/prizes/medicine/1967/summary/" /><!-- OG --> <link rel="icon" href="https://www.nobelprize.org/uploads/2018/08/Nobel-favicon-50x50.png" sizes="32x32" /> <link rel="icon" href="https://www.nobelprize.org/uploads/2018/08/Nobel-favicon-232x232.png" sizes="192x192" /> <link rel="apple-touch-icon" href="https://www.nobelprize.org/uploads/2018/08/Nobel-favicon-188x188.png" /> <meta name="msapplication-TileImage" content="https://www.nobelprize.org/uploads/2018/08/Nobel-favicon.png" /> <style type="text/css" id="wp-custom-css"> .summit-event-nav .prizes-nav-top-tier li:last-of-type { border-right: 0; } .ot-sdk-show-settings:hover, .ot-sdk-show-settings { background-color: #CEA152 !important; border-color: #CEA152 !important; color: #FFFFFF !important; } </style> </head> <body class="prize-content-type "> <!-- Google Tag Manager (noscript) --> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-WDHZ8W5" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <!-- End Google Tag Manager (noscript) --> <!--[if lte IE 9]> <p class="browserupgrade">You are using an <strong>outdated</strong> browser. Please <a href="https://browsehappy.com/">upgrade your browser</a> to improve your experience and security.</p> <![endif]--> <a class="skip-link screen-reader-text" href="#content"> Skip to content </a> <header class="site-header js-site-header" role="banner" itemscope="itemscope" itemtype="http://schema.org/WPHeader"> <div class="site-header__wrapper container"> <div class="site-banner" itemscope itemtype="http://schema.org/Organization"> <div class="site-banner-logo" itemscope itemtype="http://schema.org/Organization"> <h1 class="site-logo" itemprop="logo"> <a itemprop="url" href="https://www.nobelprize.org" name="top" aria-label="The Nobel Prize"> <svg class="site-logo-icon site-logo-icon--big" xmlns="http://www.w3.org/2000/svg" width="77" height="60" fill="none" viewBox="0 0 77 60"><path d="M25.298 1.997h-4.631v14.66h-2.21V1.997h-4.674V0h11.515v1.997ZM42.126 0v16.657h-2.21V8.711h-9.179v7.946h-2.21V0h2.21v6.714h9.179V0h2.21Zm14.617 16.657V14.66h-7.691V8.711h7.011V6.714h-7.011V1.997h7.564V0h-9.731v16.657h9.858Zm-43.045 5.014V38.33h-1.53L2.225 25.41v12.918H.1V21.67h1.7l9.773 12.578V21.671h2.125Zm12.025-.34c-4.801 0-8.71 3.867-8.71 8.669 0 4.802 3.909 8.669 8.71 8.669 4.802 0 8.711-3.867 8.711-8.669 0-4.802-3.91-8.669-8.71-8.669Zm.043 2.083c3.527 0 6.459 2.932 6.459 6.586 0 3.654-2.932 6.586-6.46 6.586-3.526 0-6.458-2.932-6.458-6.586 0-3.654 2.932-6.586 6.459-6.586Zm23.116 9.943c0 2.932-2.125 4.972-5.227 4.972h-5.779V21.67h5.27c3.059 0 4.971 1.53 4.971 3.995 0 1.614-.85 2.89-2.252 3.527 1.87.68 3.017 2.167 3.017 4.164Zm-8.796-9.73v4.8h3.06c1.53 0 2.846-.934 2.846-2.506 0-1.573-1.232-2.295-2.847-2.295h-3.06Zm6.629 9.772c0-1.87-1.445-3.017-3.145-3.017h-3.484v6.034h3.484c1.7-.042 3.145-1.147 3.145-3.017Zm15.467 4.93V36.33h-7.649v-5.949h7.012v-1.997h-7.012V23.67h7.564V21.67h-9.773V38.33h9.858ZM76.29 36.33v1.998h-9.731V21.67h2.21v14.66h7.52Zm-65.057 15.85c2.89 0 4.93-1.784 4.93-4.419 0-2.592-2.04-4.42-4.972-4.42H5.41V60h2.21v-7.819h3.612Zm0-6.841c1.615 0 2.72.892 2.72 2.422 0 1.53-1.105 2.422-2.72 2.422H7.621V45.34h3.612Zm12.11 6.756h-1.742V60h-2.21V43.343h5.78c2.89 0 4.929 1.742 4.929 4.376 0 2.423-1.742 4.08-4.25 4.335l6.035 7.904H29.25l-5.906-7.862ZM21.602 50.1h3.612c1.657 0 2.72-.85 2.72-2.38 0-1.53-1.105-2.38-2.72-2.38h-3.612v4.76Zm15.17-6.756h-2.21V60h2.21V43.343Zm3.442 14.915L49.86 45.34h-8.71v-1.997h11.557v1.614l-9.73 13.046h9.985V60H40.213v-1.742ZM66.304 60v-1.997h-7.691v-5.95h7.011v-1.996h-7.011V45.34h7.564v-1.997h-9.731V60h9.858Z"/></svg> <svg class="site-logo-icon site-logo-icon--small" xmlns="http://www.w3.org/2000/svg" width="171" height="16" fill="none" viewBox="0 0 171 16"><path d="M10.3 2.222H6.256v12.684H4.344V2.222H.3V.494h9.963v1.728h.037ZM24.822.494v14.412H22.91V8.03h-7.94v6.875h-1.913V.494h1.912v5.809h7.941V.494h1.912Zm12.61 12.684v1.728h-8.53V.494h8.42v1.728h-6.544v4.081h6.066v1.728h-6.066v5.147h6.654ZM57.322.494v14.412h-1.324L47.397 3.729v11.177h-1.839V.494h1.47l8.457 10.883V.494h1.838ZM60.19 7.7c0-4.154 3.382-7.5 7.537-7.5 4.154 0 7.536 3.346 7.536 7.5s-3.382 7.5-7.537 7.5c-4.154 0-7.536-3.346-7.536-7.5Zm13.162 0c0-3.162-2.537-5.699-5.589-5.699-3.051 0-5.588 2.537-5.588 5.699s2.537 5.699 5.588 5.699c3.052 0 5.588-2.537 5.588-5.699Zm14.411 2.904c0 2.537-1.838 4.302-4.522 4.302h-5.037V.494h4.56c2.646 0 4.3 1.324 4.3 3.456 0 1.397-.735 2.5-1.948 3.051 1.655.589 2.647 1.875 2.647 3.603Zm-7.61-8.419V6.34H82.8c1.324 0 2.463-.81 2.463-2.17 0-1.36-1.066-1.985-2.463-1.985h-2.647Zm5.735 8.456c0-1.617-1.25-2.61-2.72-2.61h-3.015v5.22h3.015c1.47-.036 2.72-.992 2.72-2.61Zm13.383 2.537v1.728h-8.53V.494h8.42v1.728h-6.545v4.081h6.103v1.728h-6.066v5.147h6.618Zm12.206 0v1.728h-8.42V.494h1.912v12.684h6.508Zm15.514-8.86c0 2.28-1.765 3.823-4.265 3.823h-3.125v6.765h-1.911V.494h5c2.537 0 4.301 1.581 4.301 3.824Zm-1.912 0c0-1.324-.955-2.096-2.353-2.096h-3.125v4.191h3.125c1.398 0 2.353-.772 2.353-2.095Zm8.089 3.75h-1.508v6.838h-1.911V.494h5c2.5 0 4.264 1.507 4.264 3.787 0 2.095-1.507 3.53-3.676 3.75l5.22 6.838h-2.279l-5.11-6.801Zm-1.471-1.728h3.125c1.434 0 2.353-.736 2.353-2.06 0-1.323-.956-2.058-2.353-2.058h-3.125V6.34ZM142.91.494h1.912v14.412h-1.912V.494ZM147.8 13.4l8.346-11.177h-7.537V.494h10v1.397l-8.419 11.287h8.639v1.728H147.8v-1.508Zm22.537-.221v1.728h-8.53V.494h8.42v1.728h-6.545v4.081h6.067v1.728h-6.067v5.147h6.655Z"/></svg> </a> </h1> </div> <div class="mobile-actions"> <div class="mobile-search"> <button type="button" id="search-mobile-trigger-js" aria-controls="header-search-form" aria-expanded="false"> <svg class="search-open" xmlns="http://www.w3.org/2000/svg" width="24" height="24" viewBox="0 0 24 24" fill="none" role="img" aria-labelledby="desktop-search-title"> <title id="desktop-search-title">Open the search menu</title> <path fill="#2E2A25" d="m19.6 21-6.3-6.3A6.096 6.096 0 0 1 9.5 16c-1.817 0-3.354-.63-4.612-1.887C3.629 12.854 3 11.317 3 9.5c0-1.817.63-3.354 1.888-4.612C6.146 3.629 7.683 3 9.5 3c1.817 0 3.354.63 4.613 1.888C15.37 6.146 16 7.683 16 9.5a6.096 6.096 0 0 1-1.3 3.8l6.3 6.3-1.4 1.4ZM9.5 14c1.25 0 2.313-.438 3.188-1.313C13.562 11.813 14 10.75 14 9.5c0-1.25-.438-2.313-1.313-3.188C11.813 5.438 10.75 5 9.5 5c-1.25 0-2.313.438-3.188 1.313S5 8.25 5 9.5c0 1.25.438 2.313 1.313 3.188C7.188 13.562 8.25 14 9.5 14Z"/> </svg> <svg class="search-close" xmlns="http://www.w3.org/2000/svg" width="24" height="24" fill="#2E2A25" role="img" aria-labelledby="desktop-search-title"> <title id="desktop-search-title">Close the search menu</title> <path d="M6.4 19 5 17.6l5.6-5.6L5 6.4 6.4 5l5.6 5.6L17.6 5 19 6.4 13.4 12l5.6 5.6-1.4 1.4-5.6-5.6L6.4 19Z"/> </svg> </button> <!-- Note: Exists only to close the mobile navigation when JS is disabled --> <noscript> <a id="mobile-close-js" class="toggle-close" href="#"> <span>Close Mobile Menu</span> </a> </noscript> </div> <div class="mobile-nav"> <button type="button" id="mobile-nav-js" class="toggle" aria-controls="main-navigation-js" aria-expanded="false"> <span> Toggle Mobile Menu </span> </button> </div> </div> </div> <nav id="main-navigation-js" class="site-main-navigation" role="navigation" itemscope="itemscope" itemtype="http://schema.org/SiteNavigationElement" aria-label="Main menu" aria-hidden="true"> <ul id="menu-header_top" class="main-menu" role="menu"><li id="menu-item-28259" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-28259" role="menuitem"><a href="/prizes/">Nobel Prizes & laureates</a> <ul class="sub-menu" role="menu" aria-hidden="true"> <li id="menu-item-175174" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-175174" role="menuitem"><a href="/prizes/lists/all-nobel-prizes/">All Nobel Prizes</a></li> <li id="menu-item-222451" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-222451" role="menuitem"><a href="https://www.nobelprize.org/all-nobel-prizes-2024/">All Nobel Prizes 2024</a></li> <li id="menu-item-48853" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-48853" role="menuitem"><a href="/prizes/physics/">Physics prize</a></li> <li id="menu-item-48854" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-48854" role="menuitem"><a href="/prizes/chemistry/">Chemistry prize</a></li> <li id="menu-item-48855" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-48855" role="menuitem"><a href="/prizes/medicine/">Medicine prize</a></li> <li id="menu-item-48856" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-48856" role="menuitem"><a href="/prizes/literature/">Literature prize</a></li> <li id="menu-item-48857" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-48857" role="menuitem"><a href="/prizes/peace/">Peace prize</a></li> <li id="menu-item-48858" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-48858" role="menuitem"><a href="/prizes/economic-sciences/">Prize in economic sciences</a></li> </ul> </li> <li id="menu-item-28260" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-28260" role="menuitem"><a href="/about/">About</a> <ul class="sub-menu" role="menu" aria-hidden="true"> <li id="menu-item-43405" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-43405" role="menuitem"><a href="/about-the-nobel-prize/">About the prize</a></li> <li id="menu-item-43408" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-43408" role="menuitem"><a href="/alfred-nobel">Alfred Nobel</a></li> <li id="menu-item-43407" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-43407" role="menuitem"><a href="/about/nobel-prize-award-ceremonies/">Award ceremonies</a></li> <li id="menu-item-43409" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-43409" role="menuitem"><a href="/nomination">Nomination</a></li> <li id="menu-item-43406" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-43406" role="menuitem"><a href="/the-nobel-prize-organisation">Organisation</a></li> </ul> </li> <li id="menu-item-28261" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-28261" role="menuitem"><a href="/stories/">Stories</a></li> <li id="menu-item-28262" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-28262" role="menuitem"><a href="/educational/">Educational</a></li> <li id="menu-item-219562" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-219562" role="menuitem"><a href="/events-museums/">Events & museums</a></li> <li role="menuitem" class="searchform"> <button type="button" id="search-trigger-js" aria-controls="header-search-form" aria-expanded="false"> <svg class="search-open" xmlns="http://www.w3.org/2000/svg" width="24" height="24" viewbox="0 0 24 24" fill="none" role="img" aria-labelledby="desktop-search-title"> <title id="desktop-search-title">Open the search menu</title> <path fill="#2E2A25" d="m19.6 21-6.3-6.3A6.096 6.096 0 0 1 9.5 16c-1.817 0-3.354-.63-4.612-1.887C3.629 12.854 3 11.317 3 9.5c0-1.817.63-3.354 1.888-4.612C6.146 3.629 7.683 3 9.5 3c1.817 0 3.354.63 4.613 1.888C15.37 6.146 16 7.683 16 9.5a6.096 6.096 0 0 1-1.3 3.8l6.3 6.3-1.4 1.4ZM9.5 14c1.25 0 2.313-.438 3.188-1.313C13.562 11.813 14 10.75 14 9.5c0-1.25-.438-2.313-1.313-3.188C11.813 5.438 10.75 5 9.5 5c-1.25 0-2.313.438-3.188 1.313S5 8.25 5 9.5c0 1.25.438 2.313 1.313 3.188C7.188 13.562 8.25 14 9.5 14Z"></path> </svg> <svg class="search-close" xmlns="http://www.w3.org/2000/svg" width="24" height="24" fill="#2E2A25" role="img" aria-labelledby="desktop-search-title"> <title id="desktop-search-title">Close the search menu</title> <path d="M6.4 19 5 17.6l5.6-5.6L5 6.4 6.4 5l5.6 5.6L17.6 5 19 6.4 13.4 12l5.6 5.6-1.4 1.4-5.6-5.6L6.4 19Z"></path> </svg> </button> </li> </ul> </nav> </div> <div id="header-search-form" class="header-search-form js-header-search-form" aria-hidden="true"> <div class="container"> <form class="searchform -header" method="GET" action="/search/" > <label for="search-form-input-header" class="screen-reader-text"> Header Search </label> <input type="search" class="input" name="s" id="search-form-input-header" placeholder="Enter your search here" value="" required> <button type="submit"> <svg width="24" height="24" viewBox="0 0 24 24" xmlns="http://www.w3.org/2000/svg" fill="#2E2A25" role="img" aria-labelledby="submit-search-title-header -header"> <title id="submit-search-title-header">Submit a search term</title> <path d="m19.6 21-6.3-6.3A6.096 6.096 0 0 1 9.5 16c-1.817 0-3.354-.63-4.612-1.887C3.629 12.854 3 11.317 3 9.5c0-1.817.63-3.354 1.888-4.612C6.146 3.629 7.683 3 9.5 3c1.817 0 3.354.63 4.613 1.888C15.37 6.146 16 7.683 16 9.5a6.096 6.096 0 0 1-1.3 3.8l6.3 6.3-1.4 1.4ZM9.5 14c1.25 0 2.313-.438 3.188-1.313C13.562 11.813 14 10.75 14 9.5c0-1.25-.438-2.313-1.313-3.188C11.813 5.438 10.75 5 9.5 5c-1.25 0-2.313.438-3.188 1.313S5 8.25 5 9.5c0 1.25.438 2.313 1.313 3.188C7.188 13.562 8.25 14 9.5 14Z"/> </svg> </button> </form> </div> </div> </header> <main id="content" role="main" class="nobel-content"> <noscript id="noscript-list"> <h3> Enhanced Page Navigation </h3> <ol> <li> <a href="https://www.nobelprize.org/prizes/medicine/1967/summary/" title="The Nobel Prize in Physiology or Medicine 1967" data-related="0" > The Nobel Prize in Physiology or Medicine 1967 </a> </li> <li> <a href="https://www.nobelprize.org/prizes/medicine/1967/ceremony-speech/" title="Award ceremony speech" data-related="1" > Award ceremony speech </a> </li> </ol> </noscript> <div id="pjax-well" class="container page-content-area"> <div class="pjax-container"> <section class="page-section laureate-facts"> <aside class="page-aside border-top"> <header class="header"> <h5 class="heading"> The Nobel Prize in Physiology or Medicine 1967 </h5> </header> <nav class="aside-navigation aside-navigation--desktop" aria-label="In Page Navigation"> <ul class="aside-navigation__list"><li class="aside-navigation__list-item"> <a href="https://www.nobelprize.org/prizes/medicine/1967/summary/" aria-current="page" > Summary </a> </li><li class="aside-navigation__list-item">Laureates<ul class="aside-navigation__list"><li class="aside-navigation__list-item"> <a href="https://www.nobelprize.org/prizes/medicine/1967/granit/facts/" aria-current="false" > Ragnar Granit </a> </li><li class="aside-navigation__list-item"> <a href="https://www.nobelprize.org/prizes/medicine/1967/hartline/facts/" aria-current="false" > Keffer Hartline </a> </li><li class="aside-navigation__list-item"> <a href="https://www.nobelprize.org/prizes/medicine/1967/wald/facts/" aria-current="false" > George Wald </a> </li></ul></li><li class="aside-navigation__list-item"> <a href="https://www.nobelprize.org/prizes/medicine/1967/ceremony-speech/" aria-current="false" > Presentation Speech </a> </li></ul></nav> <footer class="footer"> <div class="share-this"> <h6 class="heading"> Share this </h6> <ul class="socialicons" aria-label="Social sharing links"> <li class="socialicon" data-social="facebook"> <a href="https://www.facebook.com/sharer.php?u=https%3A%2F%2Fwww.nobelprize.org%2Fprizes%2Fmedicine%2F1967%2Fsummary%2F&t=The+Nobel+Prize+in+Physiology+or+Medicine+1967" data-target="https://www.nobelprize.org/prizes/medicine/1967/summary/" target="_blank" rel="noreferrer" > <svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40"><path d="M14.526 34h-3.96A4.572 4.572 0 0 1 6 29.43V10.57C6 8.051 8.051 6 10.571 6H29.43A4.577 4.577 0 0 1 34 10.57v18.854c0 2.52-2.051 4.57-4.571 4.57h-3.492a.573.573 0 0 1-.571-.571V22.305c0-.314.257-.571.571-.571h2.229l.405-3.228h-2.634a.573.573 0 0 1-.571-.571v-3.28c0-.314.257-.57.571-.57h2.709v-3.229h-4.892a1.62 1.62 0 0 0-1.617 1.617v5.462a.573.573 0 0 1-.571.571h-2.709v3.228h2.709c.314 0 .571.257.571.571v11.118a.59.59 0 0 1-.166.406c-.148.148-.171.171-7.44.171h-.005ZM10.57 7.143a3.43 3.43 0 0 0-3.428 3.427v18.854a3.43 3.43 0 0 0 3.423 3.428h10.423V22.87H18.28a.573.573 0 0 1-.571-.572v-4.37c0-.314.257-.571.571-.571h2.709v-4.89c0-1.52 1.24-2.76 2.76-2.76h5.462c.315 0 .572.257.572.571v4.37a.573.573 0 0 1-.572.572h-2.708v2.137h2.708a.56.56 0 0 1 .429.194c.109.126.16.286.137.451l-.548 4.37a.573.573 0 0 1-.566.504h-2.16v9.975h2.92a3.43 3.43 0 0 0 3.428-3.428V10.57a3.43 3.43 0 0 0-3.428-3.427H10.57Z"/></svg> <span class="screen-reader-text"> Facebook </span> </a> </li> <li class="socialicon" data-social="twitter"> <a href="https://twitter.com/intent/tweet?text=The+Nobel+Prize+in+Physiology+or+Medicine+1967&url=https%3A%2F%2Fwww.nobelprize.org%2Fprizes%2Fmedicine%2F1967%2Fsummary%2F" data-target="https://www.nobelprize.org/prizes/medicine/1967/summary/" target="_blank" rel="noreferrer" > <svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40"><path fill-rule="evenodd" d="M11.143 6h17.714A5.148 5.148 0 0 1 34 11.143v17.714A5.148 5.148 0 0 1 28.857 34H11.143A5.148 5.148 0 0 1 6 28.857V11.143A5.148 5.148 0 0 1 11.143 6Zm17.714 26.857c2.205 0 4-1.795 4-4V11.143c0-2.205-1.795-4-4-4H11.143c-2.205 0-4 1.795-4 4v17.714c0 2.205 1.795 4 4 4h17.714Zm-.995-22.384a.572.572 0 0 1 .847.768l-6.933 7.65 6.977 9.923a.572.572 0 0 1-.468.9h-3.714a.571.571 0 0 1-.468-.243l-5.205-7.404-6.76 7.46a.57.57 0 0 1-.808.04.572.572 0 0 1-.04-.808l6.934-7.65-6.977-9.923a.572.572 0 0 1 .468-.9h3.714c.186 0 .36.09.467.243l5.206 7.404 6.76-7.46Zm-15.047.956L24.869 28.57h2.317L15.132 11.43h-2.317Z" clip-rule="evenodd"/></svg> <span class="screen-reader-text"> X </span> </a> </li> <li class="socialicon" data-social="linkedin"> <a href="https://www.linkedin.com/shareArticle?mini=true&url=https%3A%2F%2Fwww.nobelprize.org%2Fprizes%2Fmedicine%2F1967%2Fsummary%2F&title=The+Nobel+Prize+in+Physiology+or+Medicine+1967" data-target="https://www.nobelprize.org/prizes/medicine/1967/summary/" target="_blank" rel="noreferrer" > <svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40"><path fill-rule="evenodd" d="M12.909 14.251a2.557 2.557 0 0 1-2.555-2.554 2.56 2.56 0 0 1 2.555-2.554 2.56 2.56 0 0 1 2.554 2.554 2.56 2.56 0 0 1-2.554 2.554Zm0-3.965c-.778 0-1.412.634-1.412 1.411s.634 1.412 1.412 1.412c.777 0 1.411-.635 1.411-1.412 0-.777-.634-1.411-1.411-1.411Z" clip-rule="evenodd"/><path d="M28.771 28.211c0 .315.258.572.572.572l-.006-.006a.573.573 0 0 0 .572-.571v-7.292c0-3.605-2.509-4.891-4.852-4.891-1.457 0-2.497.383-3.44 1v-.532a.573.573 0 0 0-.571-.571h-3.612a.573.573 0 0 0-.571.571v11.715c0 .314.257.571.571.571a.573.573 0 0 0 .572-.571V17.063h2.468v1.108a.574.574 0 0 0 .943.44c1.057-.891 2.034-1.44 3.646-1.44 1.114 0 3.708.366 3.708 3.749v7.291ZM14.611 28.783a.573.573 0 0 1-.571-.572V17.07h-2.543V28.21a.573.573 0 0 1-.571.572.573.573 0 0 1-.572-.572V16.497c0-.314.257-.571.572-.571h3.685c.315 0 .572.257.572.571v11.714a.573.573 0 0 1-.572.572Z"/><path d="M25.657 28.783a.573.573 0 0 1-.571-.572V22.83c0-1.286-.412-1.738-1.577-1.738-1.252 0-1.886.458-1.886 1.355v5.765a.573.573 0 0 1-.572.572.573.573 0 0 1-.571-.572v-5.765c0-1.56 1.131-2.497 3.029-2.497 1.897 0 2.72.971 2.72 2.88v5.382a.573.573 0 0 1-.572.572Z"/><path fill-rule="evenodd" d="M11.143 34h17.714A5.15 5.15 0 0 0 34 28.857V11.143A5.15 5.15 0 0 0 28.857 6H11.143A5.15 5.15 0 0 0 6 11.143v17.714A5.15 5.15 0 0 0 11.143 34Zm-4-22.857c0-2.206 1.794-4 4-4h17.714c2.206 0 4 1.794 4 4v17.714c0 2.206-1.794 4-4 4H11.143c-2.206 0-4-1.794-4-4V11.143Z" clip-rule="evenodd"/></svg> <span class="screen-reader-text"> LinkedIn </span> </a> </li> <li class="socialicon" data-social="email"> <a data-target="https://www.nobelprize.org/prizes/medicine/1967/summary/" href="/cdn-cgi/l/email-protection#5e612d2b3c343b3d2a63182c31337b6c6e10313c3b320e2c37243b70312c39647b6c6e0a363b7b6c6e10313c3b327b6c6e0e2c37243b7b6c6e37307b6c6e0e36272d3731323139277b6c6e312c7b6c6e133b3a373d37303b7b6c6e6f676869787d6e6d66653c313a2763362a2a2e2d6471712929297030313c3b322e2c37243b70312c39712e2c37243b2d71333b3a373d37303b716f676869712d2b33333f2c2771" target="_blank" rel="noreferrer"> <svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40"><path fill-rule="evenodd" d="M12.229 14.02A1.37 1.37 0 0 0 11 15.384v9.84a1.37 1.37 0 0 0 1.37 1.37h15.26a1.37 1.37 0 0 0 1.37-1.37V15.37A1.37 1.37 0 0 0 27.63 14H12.37a.5.5 0 0 0-.141.02Zm.256.98a.504.504 0 0 1-.114.013.37.37 0 0 0-.371.37v9.841a.37.37 0 0 0 .37.37h15.26a.37.37 0 0 0 .37-.37V15.37a.37.37 0 0 0-.37-.37H12.485Zm.288.88a.5.5 0 0 1 .699-.107L20 20.577l6.528-4.804a.5.5 0 0 1 .593.805l-6.825 5.023a.5.5 0 0 1-.592 0l-6.825-5.023a.5.5 0 0 1-.106-.699Z" clip-rule="evenodd"/><path fill-rule="evenodd" d="M28.857 6H11.143A5.148 5.148 0 0 0 6 11.143v17.714A5.148 5.148 0 0 0 11.143 34h17.714A5.148 5.148 0 0 0 34 28.857V11.143A5.148 5.148 0 0 0 28.857 6Zm4 22.857c0 2.205-1.795 4-4 4H11.143c-2.205 0-4-1.795-4-4V11.143c0-2.205 1.795-4 4-4h17.714c2.205 0 4 1.795 4 4v17.714Z" clip-rule="evenodd"/></svg> <span class="screen-reader-text"> Email this page </span> </a> </li> </ul> </div> </footer> </aside> <article class="page-content prize-introduction border-top" > <header class="heading"> <h1> The Nobel Prize in Physiology or Medicine 1967 </h1> </header> <select class="aside-navigation aside-navigation--mobile input-select js-aside-navigation--mobile" name="Go to laureate page"> <option value="" selected disabled>Navigate to:</option> <option value="https://www.nobelprize.org/prizes/medicine/1967/summary/" disabled selected> Summary</option><optgroup label=" Laureates"><option value="https://www.nobelprize.org/prizes/medicine/1967/granit/facts/">- Ragnar Granit</option><option value="https://www.nobelprize.org/prizes/medicine/1967/hartline/facts/">- Keffer Hartline</option><option value="https://www.nobelprize.org/prizes/medicine/1967/wald/facts/">- George Wald</option></optgroup><option value="https://www.nobelprize.org/prizes/medicine/1967/ceremony-speech/"> Presentation Speech</option></select> <div class="list-laureates border-top"> <figure class="list-laureate" itemscope itemtype="http://schema.org/Person"> <a href="https://www.nobelprize.org/prizes/medicine/1967/granit/facts/"><picture ><source data-srcset="https://www.nobelprize.org/images/granit-13196-portrait-mini-2x.jpg" media="(min-width: 220px)" /><source data-srcset="https://www.nobelprize.org/images/granit-13196-portrait-small-2x.jpg" media="(min-width: 900px)" /><source data-srcset="https://www.nobelprize.org/images/granit-13196-portrait-medium-2x.jpg" media="(min-width: 1400px)" /><img class="lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" alt="Ragnar Granit" /><noscript><img src="https://www.nobelprize.org/images/granit-13196-portrait-medium.jpg" alt="Ragnar Granit" /></noscript></picture></a><figcaption class="figcaption"><p class="figcaption__attribution">Photo from the Nobel Foundation archive.</p></figcaption> <figcaption> <h3 itemprop="name"> <a href="https://www.nobelprize.org/prizes/medicine/1967/granit/facts/" title="Title text" itemprop="url" > Ragnar Granit </a> </h3> <p itemprop="description"> Prize share: 1/3 </p> </figcaption> </figure> <figure class="list-laureate" itemscope itemtype="http://schema.org/Person"> <a href="https://www.nobelprize.org/prizes/medicine/1967/hartline/facts/"><picture ><source data-srcset="https://www.nobelprize.org/images/hartline-13197-portrait-mini-2x.jpg" media="(min-width: 220px)" /><source data-srcset="https://www.nobelprize.org/images/hartline-13197-portrait-small-2x.jpg" media="(min-width: 900px)" /><source data-srcset="https://www.nobelprize.org/images/hartline-13197-portrait-medium-2x.jpg" media="(min-width: 1400px)" /><img class="lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" alt="Haldan Keffer Hartline" /><noscript><img src="https://www.nobelprize.org/images/hartline-13197-portrait-medium.jpg" alt="Haldan Keffer Hartline" /></noscript></picture></a><figcaption class="figcaption"><p class="figcaption__attribution">Photo from the Nobel Foundation archive.</p></figcaption> <figcaption> <h3 itemprop="name"> <a href="https://www.nobelprize.org/prizes/medicine/1967/hartline/facts/" title="Title text" itemprop="url" > Haldan Keffer Hartline </a> </h3> <p itemprop="description"> Prize share: 1/3 </p> </figcaption> </figure> <figure class="list-laureate" itemscope itemtype="http://schema.org/Person"> <a href="https://www.nobelprize.org/prizes/medicine/1967/wald/facts/"><picture ><source data-srcset="https://www.nobelprize.org/images/wald-13198-portrait-mini-2x.jpg" media="(min-width: 220px)" /><source data-srcset="https://www.nobelprize.org/images/wald-13198-portrait-small-2x.jpg" media="(min-width: 900px)" /><source data-srcset="https://www.nobelprize.org/images/wald-13198-portrait-medium-2x.jpg" media="(min-width: 1400px)" /><img class="lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" alt="George Wald" /><noscript><img src="https://www.nobelprize.org/images/wald-13198-portrait-medium.jpg" alt="George Wald" /></noscript></picture></a><figcaption class="figcaption"><p class="figcaption__attribution">Photo from the Nobel Foundation archive.</p></figcaption> <figcaption> <h3 itemprop="name"> <a href="https://www.nobelprize.org/prizes/medicine/1967/wald/facts/" title="Title text" itemprop="url" > George Wald </a> </h3> <p itemprop="description"> Prize share: 1/3 </p> </figcaption> </figure> </div> <blockquote class="border-top pageblockquote" itemscope itemtype="http://schema.org/Quotation"> The Nobel Prize in Physiology or Medicine 1967 was awarded jointly to Ragnar Granit, Haldan Keffer Hartline and George Wald "for their discoveries concerning the primary physiological and chemical visual processes in the eye" </blockquote> <footer class="border-top pagecite" itemscope itemtype="http://schema.org/citation"> <p> To cite this section <br> MLA style: The Nobel Prize in Physiology or Medicine 1967. NobelPrize.org. Nobel Prize Outreach AB 2024. Wed. 27 Nov 2024. <https://www.nobelprize.org/prizes/medicine/1967/summary/> </p> </footer> <div class="back-to-top"> <a href="#content" class="back-top-link"> Back to top </a> <svg width="18px" height="15px" viewBox="0 0 20 17" version="1.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" role="image" aria-labelledby="back-to-top-title back-to-top-desc"> <title id="back-to-top-title">Back To Top</title> <desc id="back-to-top-desc">Takes users back to the top of the page</desc> <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"> <g transform="translate(-474.000000, -9998.000000)" fill="#2E2A25"> <g transform="translate(474.000000, 9998.000000)"> <g transform="translate(10.000000, 10.000000) rotate(45.000000) translate(-10.000000, -10.000000) translate(3.000000, 3.000000)"> <rect x="0" y="0" width="2" height="14"></rect> <rect x="0" y="0" width="14" height="2"></rect> </g> <rect x="9" y="3" width="2" height="14"></rect> </g> </g> </g> </svg> </div> </article> </section> <section class="article-grid featured-content featured-content__color--default var-half-width-a "> <header class="section-header border-top"> <h3 class="section-header-h3">Nobel Prizes and laureates</h3> </header> <article class="article -halfwidth-a "> <div class="content-wrapper"> <header class="content"> <div class="title"> <h2 class="headline"> <a href="https://www.nobelprize.org/all-nobel-prizes-2024/"> <p>Nobel Prizes 2024</p> </a> </h2> </div> </header> <div class="text"> <p>Six prizes were awarded for achievements that have conferred the greatest benefit to humankind. The 12 laureates' work and discoveries range from proteins' structures and machine learning to fighting for a world free of nuclear weapons.</p> <p>See them all presented here.</p> </div> </div> <figure class="featuredimage"> <a href="https://www.nobelprize.org/all-nobel-prizes-2024/"><picture><source data-srcset="https://www.nobelprize.org/uploads/2024/10/nobelprizes_2024-992x656.jpg" media="(min-width: 220px)" /><source data-srcset="https://www.nobelprize.org/uploads/2024/10/nobelprizes_2024-1520x1008.jpg" media="(min-width: 900px)" /><source data-srcset="https://www.nobelprize.org/uploads/2024/10/nobelprizes_2024-2048x1352.jpg" media="(min-width: 1400px)" /><img class="lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" alt="Illustration" /><noscript><img src="https://www.nobelprize.org/uploads/2024/10/nobelprizes_2024-1024x676.jpg" alt="Illustration" /></noscript></picture></a> </figure> </article> </section> <section class="explore-laureates page-section"> <header class="section-header border-top"> <h3> Explore prizes and laureates </h3> <div class="info"> Look for popular awards and laureates in different fields, and discover the history of the Nobel Prize. </div> </header> <form class="exploreform" id="67477bba1ff7c" method='GET' action=''> <div class="dropdown"> <label for="mobile-dropdown" class="screen-reader-text"> Select the category or categories you would like to filter by </label> <select id="mobile-dropdown" name="filtermobile"> <option value="physics" > Physics </option> <option value="chemistry" > Chemistry </option> <option value="medicine" selected='selected' > Medicine </option> <option value="literature" > Literature </option> <option value="peace" > Peace </option> <option value="economic-sciences" > Economic Sciences </option> </select> </div> <div class="selector"> <label class="screen-reader-text">Select the category or categories you would like to filter by</label> <div class="labelbutton" tabindex="0"> <label for="physics"> <input id="physics" name="filter" type="radio" value="physics" hidden> <span> Physics </span> </label> </div> <div class="labelbutton" tabindex="0"> <label for="chemistry"> <input id="chemistry" name="filter" type="radio" value="chemistry" hidden> <span> Chemistry </span> </label> </div> <div class="labelbutton" tabindex="0"> <label for="medicine"> <input id="medicine" name="filter" type="radio" checked='checked' value="medicine" hidden> <span> Medicine </span> </label> </div> <div class="labelbutton" tabindex="0"> <label for="literature"> <input id="literature" name="filter" type="radio" value="literature" hidden> <span> Literature </span> </label> </div> <div class="labelbutton" tabindex="0"> <label for="peace"> <input id="peace" name="filter" type="radio" value="peace" hidden> <span> Peace </span> </label> </div> <div class="labelbutton" tabindex="0"> <label for="economic-sciences"> <input id="economic-sciences" name="filter" type="radio" value="economic-sciences" hidden> <span> Economic Sciences </span> </label> </div> </div> <div class="incrementor"> <label for="increment-down" class="screen-reader-text"> Decrease the year by one </label> <button id="increment-down" class="increment-down" type="button"> - </button> <label for="increment-input" class="screen-reader-text"> Choose a year you would like to search in </label> <input id="increment-input" name="prize_year" type="text" maxlength="4" class="increment-input" placeholder="2023" value="1967"> <label for="increment-up" class="screen-reader-text"> Increase the year by one </label> <button id="increment-up" class="increment-up" type="button"> + </button> </div> <div class="submit"> <button type="submit"> Explore </button> </div> </form> </section> <div class="long-scroll-preloader prize-explorer-preloader" style="text-align: center; display: none" data-target="67477bba1ff7c"> <img style="display: inline-block" src="https://www.nobelprize.org/wp-content/themes/nobelprize/assets/images/spinner.gif"> </div> <div class="prize-explorer-content container search-results" data-target="67477bba1ff7c"> </div> </div> </div> </main> <footer class="site-footer" role="contentinfo"> <div class="container"> <section class="footer-information"> <h4 class="heading"> <a href="/the-nobel-prize-organisation/">About the Nobel Prize organisation</a> </h4> <div class="footer-sections"> <div class="footer-section"> <h5> <a href="/the-nobel-prize-organisation/the-nobel-foundation/">The Nobel Foundation</a> </h5> <p>Tasked with a mission to manage Alfred Nobel's fortune and has聽ultimate responsibility for fulfilling the intentions of Nobel's will.</p> </div> <div class="footer-section"> <h5> <a href="/the-nobel-prize-organisation/prize-awarding-institutions/">The prize-awarding institutions</a> </h5> <p>For more than a century, these academic institutions have worked independently to select Nobel Prize laureates.</p> </div> <div class="footer-section"> <h5> <a href="/the-nobel-prize-organisation/outreach-organisations/">Outreach organisations</a> </h5> <p>Several outreach organisations and activities have been developed to inspire generations and disseminate knowledge about the Nobel Prize.</p> </div> </div> </section> <section class="footer-nav"> <nav class="footer-menu" role="navigation" itemscope="itemscope" itemtype="http://schema.org/SiteNavigationElement"> <ul id="menu-footer_col_1" class="footer-column-items" role="menu"><li id="menu-item-28266" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-28266" role="menuitem"><a href="https://www.nobelprize.org/press-room/">Press</a></li> <li id="menu-item-42845" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-42845" role="menuitem"><a href="https://www.nobelprize.org/contact">Contact</a></li> <li id="menu-item-28265" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-28265" role="menuitem"><a href="https://www.nobelprize.org/frequently-asked-questions/">FAQ</a></li> </ul> </nav> <nav class="footer-menu" role="navigation" itemscope="itemscope" itemtype="http://schema.org/SiteNavigationElement"> <ul id="menu-footer_col_2" class="footer-column-items" role="menu"><li id="menu-item-28268" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-28268" role="menuitem"><a href="/about/privacy-policy/">Privacy policy</a></li> <li id="menu-item-28269" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-28269" role="menuitem"><a href="/about/technical-support/">Technical support</a></li> <li id="menu-item-42844" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-42844" role="menuitem"><a href="/about/terms-of-use/">Terms of use</a></li> </ul> </nav> <nav class="footer-menu" role="navigation" itemscope="itemscope" itemtype="http://schema.org/SiteNavigationElement"> <ul id="menu-footer_col_3" class="footer-column-items" role="menu"><li id="menu-item-28272" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-28272" role="menuitem"><a href="/about/developer-zone/">For developers</a></li> <li id="menu-item-42843" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-42843" role="menuitem"><a href="/mediaplayer/">Media player</a></li> <li id="menu-item-224329" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-224329" role="menuitem"><a href="https://careers.nobelprize.org">Careers</a></li> </ul> </nav> <nav class="footer-menu footer-social" role="navigation" itemscope="itemscope" itemtype="http://schema.org/SiteNavigationElement"> <h6> Join us </h6> <ul id="menu-footer_social" class="socialmenu"><li id="menu-item-28273" class="facebook menu-item menu-item-type-custom menu-item-object-custom menu-item-28273" role="menuitem"><a href="https://www.facebook.com/nobelprize/"> <svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40"><path d="M14.526 34h-3.96A4.572 4.572 0 0 1 6 29.43V10.57C6 8.051 8.051 6 10.571 6H29.43A4.577 4.577 0 0 1 34 10.57v18.854c0 2.52-2.051 4.57-4.571 4.57h-3.492a.573.573 0 0 1-.571-.571V22.305c0-.314.257-.571.571-.571h2.229l.405-3.228h-2.634a.573.573 0 0 1-.571-.571v-3.28c0-.314.257-.57.571-.57h2.709v-3.229h-4.892a1.62 1.62 0 0 0-1.617 1.617v5.462a.573.573 0 0 1-.571.571h-2.709v3.228h2.709c.314 0 .571.257.571.571v11.118a.59.59 0 0 1-.166.406c-.148.148-.171.171-7.44.171h-.005ZM10.57 7.143a3.43 3.43 0 0 0-3.428 3.427v18.854a3.43 3.43 0 0 0 3.423 3.428h10.423V22.87H18.28a.573.573 0 0 1-.571-.572v-4.37c0-.314.257-.571.571-.571h2.709v-4.89c0-1.52 1.24-2.76 2.76-2.76h5.462c.315 0 .572.257.572.571v4.37a.573.573 0 0 1-.572.572h-2.708v2.137h2.708a.56.56 0 0 1 .429.194c.109.126.16.286.137.451l-.548 4.37a.573.573 0 0 1-.566.504h-2.16v9.975h2.92a3.43 3.43 0 0 0 3.428-3.428V10.57a3.43 3.43 0 0 0-3.428-3.427H10.57Z"></path></svg> <span class="screen-reader-text">Facebook</span> </a></li> <li id="menu-item-28274" class="twitter menu-item menu-item-type-custom menu-item-object-custom menu-item-28274" role="menuitem"><a href="https://twitter.com/NobelPrize"> <svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40"><path fill-rule="evenodd" d="M11.143 6h17.714A5.148 5.148 0 0 1 34 11.143v17.714A5.148 5.148 0 0 1 28.857 34H11.143A5.148 5.148 0 0 1 6 28.857V11.143A5.148 5.148 0 0 1 11.143 6Zm17.714 26.857c2.205 0 4-1.795 4-4V11.143c0-2.205-1.795-4-4-4H11.143c-2.205 0-4 1.795-4 4v17.714c0 2.205 1.795 4 4 4h17.714Zm-.995-22.384a.572.572 0 0 1 .847.768l-6.933 7.65 6.977 9.923a.572.572 0 0 1-.468.9h-3.714a.571.571 0 0 1-.468-.243l-5.205-7.404-6.76 7.46a.57.57 0 0 1-.808.04.572.572 0 0 1-.04-.808l6.934-7.65-6.977-9.923a.572.572 0 0 1 .468-.9h3.714c.186 0 .36.09.467.243l5.206 7.404 6.76-7.46Zm-15.047.956L24.869 28.57h2.317L15.132 11.43h-2.317Z" clip-rule="evenodd"></path></svg> <span class="screen-reader-text">Twitter</span> </a></li> <li id="menu-item-43144" class="instagram menu-item menu-item-type-custom menu-item-object-custom menu-item-43144" role="menuitem"><a href="https://www.instagram.com/nobelprize_org/?hl=en"> <svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40"><path fill-rule="evenodd" d="M28.857 34H11.143A5.15 5.15 0 0 1 6 28.857V11.143A5.15 5.15 0 0 1 11.143 6h17.714A5.15 5.15 0 0 1 34 11.143v17.714A5.15 5.15 0 0 1 28.857 34ZM11.143 7.143c-2.206 0-4 1.794-4 4v17.714c0 2.206 1.794 4 4 4h17.714c2.206 0 4-1.794 4-4V11.143c0-2.206-1.794-4-4-4H11.143Zm8.857 20c-3.937 0-7.143-3.206-7.143-7.143s3.206-7.143 7.143-7.143 7.143 3.206 7.143 7.143-3.206 7.143-7.143 7.143ZM20 14c-3.309 0-6 2.691-6 6s2.691 6 6 6 6-2.691 6-6-2.691-6-6-6Zm6-2.286a2.285 2.285 0 1 0 4.57.001 2.285 2.285 0 0 0-4.57 0Zm1.143 0c0-.628.514-1.143 1.143-1.143.628 0 1.143.515 1.143 1.143 0 .629-.515 1.143-1.143 1.143a1.146 1.146 0 0 1-1.143-1.143Z" clip-rule="evenodd"></path></svg> <span class="screen-reader-text">Instagram</span> </a></li> <li id="menu-item-43145" class="youtube menu-item menu-item-type-custom menu-item-object-custom menu-item-43145" role="menuitem"><a href="https://www.youtube.com/thenobelprize"> <svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40"><path fill-rule="evenodd" d="M11.143 34h17.714A5.15 5.15 0 0 0 34 28.857V11.143A5.15 5.15 0 0 0 28.857 6H11.143A5.15 5.15 0 0 0 6 11.143v17.714A5.15 5.15 0 0 0 11.143 34Zm-4-22.857c0-2.206 1.794-4 4-4h17.714c2.206 0 4 1.794 4 4v17.714c0 2.206-1.794 4-4 4H11.143c-2.206 0-4-1.794-4-4V11.143Zm20.2 15.143H12.65a2.753 2.753 0 0 1-2.748-2.749v-7.074a2.753 2.753 0 0 1 2.748-2.749h14.692a2.753 2.753 0 0 1 2.748 2.749v7.074a2.753 2.753 0 0 1-2.748 2.749ZM12.65 14.857c-.885 0-1.605.72-1.605 1.606v7.074c0 .886.72 1.606 1.605 1.606h14.692c.886 0 1.606-.72 1.606-1.606v-7.074c0-.886-.72-1.606-1.606-1.606H12.65Zm5.643 8.766a.753.753 0 0 1-.746-.749l-.022-5.748c0-.275.148-.526.383-.657a.753.753 0 0 1 .76.017l4.537 2.8a.746.746 0 0 1 .354.628.77.77 0 0 1-.337.64l-4.52 2.949a.766.766 0 0 1-.409.12Zm0 0h.003-.006.003Zm.375-5.794.017 4.32 3.394-2.218-3.411-2.108v.006Z" clip-rule="evenodd"></path></svg> <span class="screen-reader-text">Youtube</span> </a></li> <li id="menu-item-164548" class="linkedin menu-item menu-item-type-custom menu-item-object-custom menu-item-164548" role="menuitem"><a href="https://www.linkedin.com/company/nobelprize/"> <svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40"><path fill-rule="evenodd" d="M12.909 14.251a2.557 2.557 0 0 1-2.555-2.554 2.56 2.56 0 0 1 2.555-2.554 2.56 2.56 0 0 1 2.554 2.554 2.56 2.56 0 0 1-2.554 2.554Zm0-3.965c-.778 0-1.412.634-1.412 1.411s.634 1.412 1.412 1.412c.777 0 1.411-.635 1.411-1.412 0-.777-.634-1.411-1.411-1.411Z" clip-rule="evenodd"></path><path d="M28.771 28.211c0 .315.258.572.572.572l-.006-.006a.573.573 0 0 0 .572-.571v-7.292c0-3.605-2.509-4.891-4.852-4.891-1.457 0-2.497.383-3.44 1v-.532a.573.573 0 0 0-.571-.571h-3.612a.573.573 0 0 0-.571.571v11.715c0 .314.257.571.571.571a.573.573 0 0 0 .572-.571V17.063h2.468v1.108a.574.574 0 0 0 .943.44c1.057-.891 2.034-1.44 3.646-1.44 1.114 0 3.708.366 3.708 3.749v7.291ZM14.611 28.783a.573.573 0 0 1-.571-.572V17.07h-2.543V28.21a.573.573 0 0 1-.571.572.573.573 0 0 1-.572-.572V16.497c0-.314.257-.571.572-.571h3.685c.315 0 .572.257.572.571v11.714a.573.573 0 0 1-.572.572Z"></path><path d="M25.657 28.783a.573.573 0 0 1-.571-.572V22.83c0-1.286-.412-1.738-1.577-1.738-1.252 0-1.886.458-1.886 1.355v5.765a.573.573 0 0 1-.572.572.573.573 0 0 1-.571-.572v-5.765c0-1.56 1.131-2.497 3.029-2.497 1.897 0 2.72.971 2.72 2.88v5.382a.573.573 0 0 1-.572.572Z"></path><path fill-rule="evenodd" d="M11.143 34h17.714A5.15 5.15 0 0 0 34 28.857V11.143A5.15 5.15 0 0 0 28.857 6H11.143A5.15 5.15 0 0 0 6 11.143v17.714A5.15 5.15 0 0 0 11.143 34Zm-4-22.857c0-2.206 1.794-4 4-4h17.714c2.206 0 4 1.794 4 4v17.714c0 2.206-1.794 4-4 4H11.143c-2.206 0-4-1.794-4-4V11.143Z" clip-rule="evenodd"></path></svg> <span class="screen-reader-text">LinkedIn</span> </a></li> </ul> </nav> </section> <section class="colophon border-top"> <div class="footer-logo" itemscope itemtype="http://schema.org/Organization"> <p class="site-logo" itemprop="logo"> <a itemprop="url" href="https://www.nobelprize.org"> The Nobel Prize </a> </p> </div> <div class="copyright"> Copyright © Nobel Prize Outreach AB 2024 </div> </section> </div> </footer> <button type="button" class="to-top" tabindex="-1"> <span class="screen-reader-text"> Scroll to top </span> <svg xmlns="http://www.w3.org/2000/svg" width="45.999" height="26.001" viewBox="0 0 45.999 26.001"><path xmlns="http://www.w3.org/2000/svg" fill="#FFF" d="M5.905 24.997a3.484 3.484 0 0 1-4.893 0 3.403 3.403 0 0 1 0-4.845l19.54-19.149a3.486 3.486 0 0 1 4.895 0l19.538 19.15a3.4 3.4 0 0 1 0 4.845 3.485 3.485 0 0 1-4.893.001L22.999 9.294z"/></svg></button> <script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script type="text/javascript" src="https://www.nobelprize.org/wp-content/plugins/nobelprize-block-library/dist/js/frontend.js?ver=9af3caa4ba4635a79486" id="nobelprize_block_library_frontend-js"></script> <script type="text/javascript" src="https://www.nobelprize.org/wp-content/themes/nobelprize/dist/js/frontend.js?ver=0fc4ea04d626abf846ed" id="frontend-js"></script> <script type="text/javascript" src="https://www.nobelprize.org/wp-content/themes/nobelprize/assets/js/frontend/lib/bgset/ls.bgset.min.js?ver=1732293022" id="lazy-sizes-bg-set-js"></script> <script type="text/javascript" src="https://www.nobelprize.org/wp-content/themes/nobelprize/assets/js/frontend/lib/lazysizes/lazysizes.min.js?ver=1732293022" id="lazy-sizes-js"></script> <script type="text/javascript" src="https://www.nobelprize.org/wp-content/themes/nobelprize/assets/js/frontend/lib/objectfit/ls.object-fit.min.js?ver=1732293022" id="lazy-sizes-object-fit-js"></script> <script type="text/javascript" src="https://www.nobelprize.org/wp-content/plugins/nobelprize/assets/js/admin/lib/flickity/flickity.pkgd.js?ver=1732293022" id="flickity-js"></script> <script type="text/javascript" src="https://www.nobelprize.org/wp-content/themes/nobelprize/assets/js/frontend/lib/clamp/clamp.min.js?ver=1732293022" id="clamp-js"></script> <script type="text/javascript" src="https://stats.wp.com/e-202448.js" id="jetpack-stats-js" data-wp-strategy="defer"></script> <script type="text/javascript" id="jetpack-stats-js-after"> /* <![CDATA[ */ _stq = window._stq || []; _stq.push([ "view", JSON.parse("{\"v\":\"ext\",\"blog\":\"197939892\",\"post\":\"0\",\"tz\":\"1\",\"srv\":\"www.nobelprize.org\",\"j\":\"1:13.9.1\"}") ]); _stq.push([ "clickTrackerInit", "197939892", "0" ]); /* ]]> */ </script> <script type="text/javascript" src="https://www.nobelprize.org/wp-includes/js/jquery/jquery.min.js?ver=3.7.1" id="jquery-core-js"></script> <script type="text/javascript" src="https://www.nobelprize.org/wp-includes/js/jquery/jquery-migrate.min.js?ver=3.4.1" id="jquery-migrate-js"></script> <script type="text/javascript">window.NREUM||(NREUM={});NREUM.info={"beacon":"bam.eu01.nr-data.net","licenseKey":"NRJS-0940f7eaf4cb46e1cfe","applicationID":"212354543","transactionName":"MhBSZQoZXUZZB0UMCwtac0QLDFxYFyZdCgNFJVFWHQ==","queueTime":0,"applicationTime":209,"atts":"HldFE0IDThkaBRNfHxgI","errorBeacon":"bam.eu01.nr-data.net","agent":""}</script></body> </html> <!-- Performance optimized by Redis Object Cache. Learn more: https://wprediscache.com Retrieved 3929 objects (3 MB) from Redis using PhpRedis (v5.3.4). -->