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href="#Interphase_within_sequences_of_cellular_processes"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Interphase within sequences of cellular processes</span> </div> </a> <button aria-controls="toc-Interphase_within_sequences_of_cellular_processes-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Toggle Interphase within sequences of cellular processes subsection</span> </button> <ul id="toc-Interphase_within_sequences_of_cellular_processes-sublist" class="vector-toc-list"> <li id="toc-Interphase_and_the_cell_cycle" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Interphase_and_the_cell_cycle"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.1</span> <span>Interphase and the cell cycle</span> </div> </a> <ul id="toc-Interphase_and_the_cell_cycle-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Interphase_and_other_cellular_processes" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Interphase_and_other_cellular_processes"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2</span> <span>Interphase and other cellular processes</span> </div> </a> <ul id="toc-Interphase_and_other_cellular_processes-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>See also</span> </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Interphase_(Materials)" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Interphase_(Materials)"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Interphase (Materials)</span> </div> </a> <ul id="toc-Interphase_(Materials)-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="Table of Contents" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Toggle 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Available in 40 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-40" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">40 languages</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%B7%D9%88%D8%B1_%D8%A8%D9%8A%D9%86%D9%8A" title="طور بيني – Arabic" lang="ar" hreflang="ar" data-title="طور بيني" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-az mw-list-item"><a href="https://az.wikipedia.org/wiki/%C4%B0nterfaza" title="İnterfaza – Azerbaijani" lang="az" hreflang="az" data-title="İnterfaza" data-language-autonym="Azərbaycanca" data-language-local-name="Azerbaijani" class="interlanguage-link-target"><span>Azərbaycanca</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%87%E0%A6%A8%E0%A7%8D%E0%A6%9F%E0%A6%BE%E0%A6%B0%E0%A6%AB%E0%A7%87%E0%A6%9C" title="ইন্টারফেজ – Bangla" lang="bn" hreflang="bn" data-title="ইন্টারফেজ" data-language-autonym="বাংলা" data-language-local-name="Bangla" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D1%84%D0%B0%D0%B7%D0%B0" title="Интерфаза – Bulgarian" lang="bg" hreflang="bg" data-title="Интерфаза" data-language-autonym="Български" data-language-local-name="Bulgarian" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Interfaza_(mitoza)" title="Interfaza (mitoza) – Bosnian" lang="bs" hreflang="bs" data-title="Interfaza (mitoza)" data-language-autonym="Bosanski" data-language-local-name="Bosnian" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Interfase" title="Interfase – Catalan" lang="ca" hreflang="ca" data-title="Interfase" data-language-autonym="Català" data-language-local-name="Catalan" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Interf%C3%A1ze" title="Interfáze – Czech" lang="cs" hreflang="cs" data-title="Interfáze" data-language-autonym="Čeština" data-language-local-name="Czech" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Interphase" title="Interphase – German" lang="de" hreflang="de" data-title="Interphase" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Interfaas" title="Interfaas – Estonian" lang="et" hreflang="et" data-title="Interfaas" data-language-autonym="Eesti" data-language-local-name="Estonian" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%9C%CE%B5%CF%83%CF%8C%CF%86%CE%B1%CF%83%CE%B7" title="Μεσόφαση – Greek" lang="el" hreflang="el" data-title="Μεσόφαση" data-language-autonym="Ελληνικά" data-language-local-name="Greek" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Interfase" title="Interfase – Spanish" lang="es" hreflang="es" data-title="Interfase" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A7%DB%8C%D9%86%D8%AA%D8%B1%D9%81%D8%A7%D8%B2" title="اینترفاز – Persian" lang="fa" hreflang="fa" data-title="اینترفاز" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Interphase" title="Interphase – French" lang="fr" hreflang="fr" data-title="Interphase" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Interfase" title="Interfase – Galician" lang="gl" hreflang="gl" data-title="Interfase" data-language-autonym="Galego" data-language-local-name="Galician" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Interfaza" title="Interfaza – Croatian" lang="hr" hreflang="hr" data-title="Interfaza" data-language-autonym="Hrvatski" data-language-local-name="Croatian" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Interfase" title="Interfase – Indonesian" lang="id" hreflang="id" data-title="Interfase" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Interfase" title="Interfase – Italian" lang="it" hreflang="it" data-title="Interfase" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ka mw-list-item"><a href="https://ka.wikipedia.org/wiki/%E1%83%98%E1%83%9C%E1%83%A2%E1%83%94%E1%83%A0%E1%83%A4%E1%83%90%E1%83%96%E1%83%90" title="ინტერფაზა – Georgian" lang="ka" hreflang="ka" data-title="ინტერფაზა" data-language-autonym="ქართული" data-language-local-name="Georgian" class="interlanguage-link-target"><span>ქართული</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D1%84%D0%B0%D0%B7%D0%B0" title="Интерфаза – Kazakh" lang="kk" hreflang="kk" data-title="Интерфаза" data-language-autonym="Қазақша" data-language-local-name="Kazakh" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-ht mw-list-item"><a href="https://ht.wikipedia.org/wiki/Ent%C3%A8faz" title="Entèfaz – Haitian Creole" lang="ht" hreflang="ht" data-title="Entèfaz" data-language-autonym="Kreyòl ayisyen" data-language-local-name="Haitian Creole" class="interlanguage-link-target"><span>Kreyòl ayisyen</span></a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/%C3%8Enterfaz" title="Înterfaz – Kurdish" lang="ku" hreflang="ku" data-title="Înterfaz" data-language-autonym="Kurdî" data-language-local-name="Kurdish" class="interlanguage-link-target"><span>Kurdî</span></a></li><li class="interlanguage-link interwiki-ky mw-list-item"><a href="https://ky.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D1%84%D0%B0%D0%B7%D0%B0" title="Интерфаза – Kyrgyz" lang="ky" hreflang="ky" data-title="Интерфаза" data-language-autonym="Кыргызча" data-language-local-name="Kyrgyz" class="interlanguage-link-target"><span>Кыргызча</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Interf%C4%81ze" title="Interfāze – Latvian" lang="lv" hreflang="lv" data-title="Interfāze" data-language-autonym="Latviešu" data-language-local-name="Latvian" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Interfaz%C4%97" title="Interfazė – Lithuanian" lang="lt" hreflang="lt" data-title="Interfazė" data-language-autonym="Lietuvių" data-language-local-name="Lithuanian" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D1%84%D0%B0%D0%B7%D0%B0" title="Интерфаза – Macedonian" lang="mk" hreflang="mk" data-title="Интерфаза" data-language-autonym="Македонски" data-language-local-name="Macedonian" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E9%96%93%E6%9C%9F_(%E7%B4%B0%E8%83%9E%E5%88%86%E8%A3%82)" title="間期 (細胞分裂) – Japanese" lang="ja" hreflang="ja" data-title="間期 (細胞分裂)" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Interfase" title="Interfase – Norwegian Bokmål" lang="nb" hreflang="nb" data-title="Interfase" data-language-autonym="Norsk bokmål" data-language-local-name="Norwegian Bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-uz mw-list-item"><a href="https://uz.wikipedia.org/wiki/Interfaza" title="Interfaza – Uzbek" lang="uz" hreflang="uz" data-title="Interfaza" data-language-autonym="Oʻzbekcha / ўзбекча" data-language-local-name="Uzbek" class="interlanguage-link-target"><span>Oʻzbekcha / ўзбекча</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Interfaza" title="Interfaza – Polish" lang="pl" hreflang="pl" data-title="Interfaza" data-language-autonym="Polski" data-language-local-name="Polish" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Int%C3%A9rfase" title="Intérfase – Portuguese" lang="pt" hreflang="pt" data-title="Intérfase" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Interfaz%C4%83" title="Interfază – Romanian" lang="ro" hreflang="ro" data-title="Interfază" data-language-autonym="Română" data-language-local-name="Romanian" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru badge-Q17559452 badge-recommendedarticle mw-list-item" title="recommended article"><a href="https://ru.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D1%84%D0%B0%D0%B7%D0%B0" title="Интерфаза – Russian" lang="ru" hreflang="ru" data-title="Интерфаза" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Interf%C3%A1za" title="Interfáza – Slovak" lang="sk" hreflang="sk" data-title="Interfáza" data-language-autonym="Slovenčina" data-language-local-name="Slovak" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Interfaza" title="Interfaza – Slovenian" lang="sl" hreflang="sl" data-title="Interfaza" data-language-autonym="Slovenščina" data-language-local-name="Slovenian" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D1%84%D0%B0%D0%B7%D0%B0" title="Интерфаза – Serbian" lang="sr" hreflang="sr" data-title="Интерфаза" data-language-autonym="Српски / srpski" data-language-local-name="Serbian" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Interfas" title="Interfas – Swedish" lang="sv" hreflang="sv" data-title="Interfas" data-language-autonym="Svenska" data-language-local-name="Swedish" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/%C4%B0nterfaz" title="İnterfaz – Turkish" lang="tr" hreflang="tr" data-title="İnterfaz" data-language-autonym="Türkçe" data-language-local-name="Turkish" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%86%D0%BD%D1%82%D0%B5%D1%80%D1%84%D0%B0%D0%B7%D0%B0" title="Інтерфаза – Ukrainian" lang="uk" hreflang="uk" data-title="Інтерфаза" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/K%E1%BB%B3_trung_gian" title="Kỳ trung gian – Vietnamese" lang="vi" hreflang="vi" data-title="Kỳ trung gian" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E9%96%93%E6%9C%9F" title="間期 – Chinese" lang="zh" hreflang="zh" data-title="間期" data-language-autonym="中文" data-language-local-name="Chinese" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q835950#sitelinks-wikipedia" title="Edit interlanguage links" class="wbc-editpage">Edit links</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Namespaces"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a 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class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">G1, S and G2 phases of the cell cycle</div> <style data-mw-deduplicate="TemplateStyles:r1236090951">.mw-parser-output .hatnote{font-style:italic}.mw-parser-output div.hatnote{padding-left:1.6em;margin-bottom:0.5em}.mw-parser-output .hatnote i{font-style:normal}.mw-parser-output .hatnote+link+.hatnote{margin-top:-0.5em}@media print{body.ns-0 .mw-parser-output .hatnote{display:none!important}}</style><div role="note" class="hatnote navigation-not-searchable">Not to be confused with <a href="/wiki/Interface_(chemistry)" class="mw-redirect" title="Interface (chemistry)">Interface (chemistry)</a>.</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236090951" /><div role="note" class="hatnote navigation-not-searchable">This article is about the phase in the cell cycle. For the video game, see <a href="/wiki/Interphase_(video_game)" title="Interphase (video game)">Interphase (video game)</a>.</div> <figure class="mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/File:Interphase.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/b/b5/Interphase.png" decoding="async" width="159" height="152" class="mw-file-element" data-file-width="159" data-file-height="152" /></a><figcaption>An illustration of interphase. The <a href="/wiki/Chromatin" title="Chromatin">chromatin</a> has not yet condensed, and the cell is undergoing its normal functions.</figcaption></figure> <figure class="mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/File:Interphase_and_part_of_Telophase_of_HT1080.PNG" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dc/Interphase_and_part_of_Telophase_of_HT1080.PNG/159px-Interphase_and_part_of_Telophase_of_HT1080.PNG" decoding="async" width="159" height="85" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/d/dc/Interphase_and_part_of_Telophase_of_HT1080.PNG 1.5x" data-file-width="180" data-file-height="96" /></a><figcaption>An image of the nucleus of a cell (<a href="/wiki/HT1080" title="HT1080">HT1080</a>) currently in interphase (likely G1). Note: <a href="/wiki/Cytoplasm" title="Cytoplasm">Cytoplasm</a> of this cell or the neighboring cell is not visible (top-left), which is currently in the <a href="/wiki/Telophase" title="Telophase">telophase</a> of <a href="/wiki/Mitosis" title="Mitosis">mitosis</a>. Image taken using an optical microscope and <a href="/wiki/DAPI" title="DAPI">DAPI</a> staining of DNA.</figcaption></figure> <p><b>Interphase</b> is the active portion of the <a href="/wiki/Cell_cycle" title="Cell cycle">cell cycle</a> that includes the <a href="/wiki/G1_phase" title="G1 phase">G1</a>, <a href="/wiki/S_phase" title="S phase">S</a>, and <a href="/wiki/G2_phase" title="G2 phase">G2</a> phases, where the cell <a href="/wiki/Cell_growth" title="Cell growth">grows</a>, <a href="/wiki/DNA_replication" title="DNA replication">replicates its DNA</a>, and prepares for <a href="/wiki/Mitosis" title="Mitosis">mitosis</a>, respectively. Interphase was formerly called the "<b>resting phase</b>," but the cell in interphase is not simply <a href="/wiki/G0_phase" title="G0 phase">dormant</a>. Calling it so would be misleading since a cell in interphase is very busy <a href="/wiki/Protein_biosynthesis" title="Protein biosynthesis">synthesizing proteins</a>, <a href="/wiki/Transcription_(biology)" title="Transcription (biology)">transcribing DNA into RNA</a>, <a href="/wiki/Endocytosis" title="Endocytosis">engulfing extracellular material</a>, and <a href="/wiki/Signal_transduction" title="Signal transduction">processing signals</a>, to name just a few activities. The cell is quiescent only in <a href="/wiki/G0_phase" title="G0 phase">G0</a>. Interphase is the phase of the <a href="/wiki/Cell_cycle" title="Cell cycle">cell cycle</a> in which a typical <a href="/wiki/Cell_(biology)" title="Cell (biology)">cell</a> spends most of its life. Interphase is the "daily living" or <a href="/wiki/Metabolism" title="Metabolism">metabolic</a> phase of the cell, in which the cell obtains <a href="/wiki/Nutrient" title="Nutrient">nutrients</a> and <a href="/wiki/Metabolism" title="Metabolism">metabolizes</a> them, grows, replicates its DNA in preparation for <a href="/wiki/Mitosis" title="Mitosis">mitosis</a>, and conducts other "normal" cell functions.<sup id="cite_ref-Marieb2000_1-0" class="reference"><a href="#cite_note-Marieb2000-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p><p>A common misconception is that interphase is the first stage of <a href="/wiki/Mitosis" title="Mitosis">mitosis</a>, but since mitosis is the division of the <a href="/wiki/Cell_nucleus" title="Cell nucleus">nucleus</a>, <a href="/wiki/Prophase" title="Prophase">prophase</a> is actually the first stage.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>In interphase, the cell gets itself ready for <a href="/wiki/Mitosis" title="Mitosis">mitosis</a> or <a href="/wiki/Meiosis" title="Meiosis">meiosis</a>. <a href="/wiki/Somatic_cell" title="Somatic cell">Somatic cells</a>, or normal <a href="/wiki/Diploid" class="mw-redirect" title="Diploid">diploid</a> cells of the body, go through mitosis in order to reproduce themselves through cell division, whereas diploid <a href="/wiki/Germ_cell" title="Germ cell">germ cells</a> (i.e., primary <a href="/wiki/Spermatocyte" title="Spermatocyte">spermatocytes</a> and primary <a href="/wiki/Oocyte" title="Oocyte">oocytes</a>) go through <a href="/wiki/Meiosis" title="Meiosis">meiosis</a> in order to create haploid <a href="/wiki/Gametes" class="mw-redirect" title="Gametes">gametes</a> (i.e., <a href="/wiki/Sperm" title="Sperm">sperm</a> and <a href="/wiki/Ovum" class="mw-redirect" title="Ovum">ova</a>) for the purpose of sexual reproduction. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Stages_of_interphase">Stages of interphase</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interphase&action=edit&section=1" title="Edit section: Stages of interphase"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>There are three stages of cellular interphase, with each phase ending when a <a href="/wiki/Cell_cycle_checkpoint" title="Cell cycle checkpoint">cellular checkpoint</a> checks the accuracy of the stage's completion before proceeding to the next. The stages of interphase are: </p> <ul><li><a href="/wiki/G1_phase" title="G1 phase">G<sub>1</sub></a> (Gap 1), in which the cell grows and functions normally. During this time, a high amount of <a href="/wiki/Protein_biosynthesis" title="Protein biosynthesis">protein synthesis</a> occurs and the cell grows (to about double its original size) – more <a href="/wiki/Organelle" title="Organelle">organelles</a> are produced and the volume of the <a href="/wiki/Cytoplasm" title="Cytoplasm">cytoplasm</a> increases. If the cell is not to divide again, it will enter <a href="/wiki/G0_phase" title="G0 phase">G<sub>0</sub></a>.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></li> <li><a href="/wiki/S_phase" title="S phase">Synthesis</a> (S), in which the cell synthesizes its DNA and the amount of DNA is doubled but the number of chromosomes remains constant (via <a href="/wiki/Semiconservative_replication" title="Semiconservative replication">semiconservative replication</a>).</li> <li><a href="/wiki/G2_phase" title="G2 phase">G<sub>2</sub></a> (Gap 2), in which the cell resumes its growth in preparation for division. The cell continues to grow until mitosis begins. In plants, chloroplasts divide during G2.</li> <li>In addition, some cells that do not divide often or ever, enter a stage called <a href="/wiki/G0_phase" title="G0 phase">G<sub>0</sub></a> (Gap zero), which is either a stage separate from interphase or an extended <a href="/wiki/G1_phase" title="G1 phase">G<sub>1</sub></a>.</li></ul> <p>The duration of time spent in interphase and in each stage of interphase is variable and depends on both the type of cell and the species of organism it belongs to. Most cells of adult <a href="/wiki/Mammal" title="Mammal">mammals</a> spend about 24 hours in interphase; this accounts for about 90%-96% of the total time involved in cell division.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> Interphase includes G1, S, and G2 phases. <a href="/wiki/Mitosis" title="Mitosis">Mitosis</a> and <a href="/wiki/Cytokinesis" title="Cytokinesis">cytokinesis</a>, however, are separate from interphase. </p><p>DNA double-strand breaks can be <a href="/wiki/DNA_repair" title="DNA repair">repaired</a> during interphase by two principal processes.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> The first process, <a href="/wiki/Non-homologous_end_joining" title="Non-homologous end joining">non-homologous end joining</a> (NHEJ), can join the two broken ends of DNA in the <a href="/wiki/G1_phase" title="G1 phase">G1</a>, <a href="/wiki/S_phase" title="S phase">S</a> and <a href="/wiki/G2_phase" title="G2 phase">G2</a> phases of interphase. The second process, <a href="/wiki/Homologous_recombination" title="Homologous recombination">homologous recombinational</a> repair (HRR), is more accurate than NHEJ in repairing double-strand breaks. However HRR is only active during the S and G2 phases of interphase when <a href="/wiki/DNA_replication" title="DNA replication">DNA replication</a> is either partially or fully accomplished, since HRR requires two adjacent <a href="/wiki/Homologous_chromosomes" class="mw-redirect" title="Homologous chromosomes">homologous chromosomes</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Interphase_within_sequences_of_cellular_processes">Interphase within sequences of cellular processes</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interphase&action=edit&section=2" title="Edit section: Interphase within sequences of cellular processes"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Interphase_and_the_cell_cycle">Interphase and the cell cycle</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interphase&action=edit&section=3" title="Edit section: Interphase and the cell cycle"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>When G<sub>2</sub> is completed, the cell enters a relatively brief period of nuclear and cellular division, composed of mitosis and cytokinesis, respectively. After the successful completion of mitosis and cytokinesis, both resulting <a href="/wiki/Daughter_cell" class="mw-redirect" title="Daughter cell">daughter cells</a> re-enter G<sub>1</sub> of interphase. </p><p>In the <a href="/wiki/Cell_cycle" title="Cell cycle">cell cycle</a>, interphase is preceded by <a href="/wiki/Telophase" title="Telophase">telophase</a> and <a href="/wiki/Cytokinesis" title="Cytokinesis">cytokinesis</a> of the <a href="/wiki/Cell_division" title="Cell division">M phase</a>. In alternative fashion, interphase is sometimes interrupted by <a href="/wiki/G0_phase" title="G0 phase">G<sub>0</sub> phase</a>, which, in some circumstances, may then end and be followed by the remaining stages of interphase. After the successful completion of the <a href="/wiki/Cell_cycle_checkpoint#G2_Checkpoint" title="Cell cycle checkpoint">G<sub>2</sub> checkpoint</a>, the final checkpoint in interphase, the cell proceeds to <a href="/wiki/Prophase" title="Prophase">prophase</a>, or in plants to <a href="/wiki/Preprophase" title="Preprophase">preprophase</a>, which is the first stage of mitosis. </p><p>G<sub>0</sub> phase is viewed as either an extended G<sub>1</sub> phase where the cell is neither dividing nor preparing to divide, or as a distinct <a href="https://en.wiktionary.org/wiki/quiescent" class="extiw" title="wikt:quiescent">quiescent</a> stage which occurs outside of the cell cycle.<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Interphase_and_other_cellular_processes">Interphase and other cellular processes</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interphase&action=edit&section=4" title="Edit section: Interphase and other cellular processes"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In <a href="/wiki/Gamete" title="Gamete">gamete</a> production, interphase is succeeded by <a href="/wiki/Meiosis" title="Meiosis">meiosis</a>. In <a href="/wiki/Programmed_cell_death" title="Programmed cell death">programmed cell death</a>, interphase is followed or preempted by <a href="/wiki/Apoptosis" title="Apoptosis">apoptosis</a>. </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interphase&action=edit&section=5" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Prophase" title="Prophase">Prophase</a></li> <li><a href="/wiki/Prometaphase" title="Prometaphase">Prometaphase</a></li> <li><a href="/wiki/Metaphase" title="Metaphase">Metaphase</a></li> <li><a href="/wiki/Anaphase" title="Anaphase">Anaphase</a></li> <li><a href="/wiki/Telophase" title="Telophase">Telophase</a></li> <li><a href="/wiki/Cytokinesis" title="Cytokinesis">Cytokinesis</a></li> <li><a href="/wiki/Cytoskeleton" title="Cytoskeleton">Cytoskeleton</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Interphase_(Materials)"><span id="Interphase_.28Materials.29"></span>Interphase (Materials)</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interphase&action=edit&section=6" title="Edit section: Interphase (Materials)"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The transition region between two materials. For example between the <a href="/wiki/Fiber" title="Fiber">fibre</a> and matrix of a <a href="/wiki/Composite_material" title="Composite material">composite material</a>. </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Interphase&action=edit&section=7" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-Marieb2000-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-Marieb2000_1-0">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFMarieb2000" class="citation book cs1">Marieb E (2000). <i>Essentials of human anatomy and physiology</i>. San Francisco: Benjamin Cummings. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0805349405" title="Special:BookSources/978-0805349405"><bdi>978-0805349405</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Essentials+of+human+anatomy+and+physiology&rft.place=San+Francisco&rft.pub=Benjamin+Cummings&rft.date=2000&rft.isbn=978-0805349405&rft.aulast=Marieb&rft.aufirst=Elaine&rfr_id=info%3Asid%2Fen.wikipedia.org%3AInterphase" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.biology.arizona.edu/Cell_bio/tutorials/cell_cycle/cells3.html">"The Cell Cycle & Mitosis Tutorial"</a>. <i>The Biology Project – Cell Biology</i>. University of Arizona.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=The+Biology+Project+%E2%80%93+Cell+Biology.&rft.atitle=The+Cell+Cycle+%26+Mitosis+Tutorial&rft_id=http%3A%2F%2Fwww.biology.arizona.edu%2FCell_bio%2Ftutorials%2Fcell_cycle%2Fcells3.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AInterphase" class="Z3988"></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFCummings2014" class="citation book cs1">Cummings MR (2014). <i>Human Heredity: Principles and Issues</i> (10th ed.). Belmont, CA: Brooks/Cole. pp. <span class="nowrap">28–</span>29.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Human+Heredity%3A+Principles+and+Issues&rft.place=Belmont%2C+CA&rft.pages=%3Cspan+class%3D%22nowrap%22%3E28-%3C%2Fspan%3E29&rft.edition=10th&rft.pub=Brooks%2FCole&rft.date=2014&rft.aulast=Cummings&rft.aufirst=MR&rfr_id=info%3Asid%2Fen.wikipedia.org%3AInterphase" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFMader2007" class="citation book cs1">Mader SS (2007). <i>Biology</i> (9th ed.). Boston, MA, USA: McGraw Hill Higher Education. <a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/978-0-07-325839-3" title="Special:BookSources/978-0-07-325839-3"><bdi>978-0-07-325839-3</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Biology&rft.place=Boston%2C+MA%2C+USA&rft.edition=9th&rft.pub=McGraw+Hill+Higher+Education&rft.date=2007&rft.isbn=978-0-07-325839-3&rft.aulast=Mader&rft.aufirst=SS&rfr_id=info%3Asid%2Fen.wikipedia.org%3AInterphase" class="Z3988"></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text">Shibata A. Regulation of repair pathway choice at two-ended DNA double-strand breaks. Mutat Res. 2017 Oct;803-805:51-55. doi: 10.1016/j.mrfmmm.2017.07.011. Epub 2017 Jul 29. Review. PMID 28781144</span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFCram" class="citation web cs1">Cram E. <a rel="nofollow" class="external text" href="http://www.madsci.org/posts/archives/nov99/942335648.Cb.r.html">"Re: Are the cells in the G0 (g zero) phase of mitosis really suspended?"</a>. <i>MadScience Network</i>. Molecular and Cellular Biology, University of California, Berkeley. 1999.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=MadScience+Network&rft.atitle=Re%3A+Are+the+cells+in+the+G0+%28g+zero%29+phase+of+mitosis+really+suspended%3F&rft.aulast=Cram&rft.aufirst=Erin&rft_id=http%3A%2F%2Fwww.madsci.org%2Fposts%2Farchives%2Fnov99%2F942335648.Cb.r.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AInterphase" class="Z3988"></span></span> </li> </ol></div></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl 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title="Cyclin B2">B2</a>, B3)</li> <li><a href="/wiki/Cyclin_D" title="Cyclin D">D</a> (<a href="/wiki/Cyclin_D1" title="Cyclin D1">D1</a>, <a href="/wiki/Cyclin_D2" title="Cyclin D2">D2</a>, <a href="/wiki/Cyclin_D3" title="Cyclin D3">D3</a>)</li> <li><a href="/wiki/Cyclin_E" title="Cyclin E">E</a> (<a href="/wiki/Cyclin_E1" title="Cyclin E1">E1</a>, <a href="/wiki/Cyclin_E2" title="Cyclin E2">E2</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cyclin-dependent_kinase" title="Cyclin-dependent kinase">CDK</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cyclin-dependent_kinase_1" title="Cyclin-dependent kinase 1">1</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_2" title="Cyclin-dependent kinase 2">2</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_3" title="Cyclin-dependent kinase 3">3</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_4" title="Cyclin-dependent kinase 4">4</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_5" title="Cyclin-dependent kinase 5">5</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_6" title="Cyclin-dependent kinase 6">6</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_7" title="Cyclin-dependent kinase 7">7</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_8" title="Cyclin-dependent kinase 8">8</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_9" title="Cyclin-dependent kinase 9">9</a></li> <li><a href="/wiki/Cyclin-dependent_kinase_10" title="Cyclin-dependent kinase 10">10</a></li> <li><a href="/wiki/CDC2L2" title="CDC2L2">11A</a></li> <li><a href="/wiki/CDC2L1" title="CDC2L1">11B</a></li> <li><a href="/wiki/CDK12" title="CDK12">12</a></li> <li><a href="/wiki/CDK13" title="CDK13">13</a></li> <li><a href="/wiki/PFTK1" title="PFTK1">14</a></li> <li><a href="/wiki/CDK-activating_kinase" title="CDK-activating kinase">CDK-activating kinase</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cyclin-dependent_kinase_inhibitor_protein" title="Cyclin-dependent kinase inhibitor protein">CDK inhibitor</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/INK4" title="INK4">INK4a/ARF</a> (<a href="/wiki/P14arf" title="P14arf">p14arf</a>/<a href="/wiki/P16" title="P16">p16</a>, <a href="/wiki/CDKN2B" title="CDKN2B">p15</a>, <a href="/wiki/CDKN2C" title="CDKN2C">p18</a>, <a href="/wiki/CDKN2D" title="CDKN2D">p19</a>)</li> <li><a href="/wiki/Cell_cycle#Inhibitors" title="Cell cycle">cip/kip</a> (<a href="/wiki/P21" title="P21">p21</a>, <a href="/wiki/CDKN1B" title="CDKN1B">p27</a>, <a href="/wiki/Cyclin-dependent_kinase_inhibitor_1C" title="Cyclin-dependent kinase inhibitor 1C">p57</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/P53_p63_p73_family" title="P53 p63 p73 family">P53 p63 p73 family</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/P53" title="P53">p53</a></li> <li><a href="/wiki/TP63" title="TP63">p63</a></li> <li><a href="/wiki/P73" title="P73">p73</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cdk1" class="mw-redirect" title="Cdk1">Cdc2</a></li> <li><a href="/wiki/Cdc25" title="Cdc25">Cdc25</a></li> <li><a href="/wiki/CDC42" title="CDC42">Cdc42</a></li> <li><a href="/wiki/Cellular_apoptosis_susceptibility_protein" title="Cellular apoptosis susceptibility protein">Cellular apoptosis susceptibility protein</a></li> <li><a href="/wiki/E2F" title="E2F">E2F</a></li> <li><a href="/wiki/Maturation_promoting_factor" title="Maturation promoting factor">Maturation promoting factor</a></li> <li><a href="/wiki/Wee1" title="Wee1">Wee</a></li> <li><a href="/wiki/Cullin" title="Cullin">Cullin</a> (<a href="/wiki/CUL7" title="CUL7">CUL7</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Phases and<br />checkpoints</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a class="mw-selflink selflink">Interphase</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/G1_phase" title="G1 phase">G<sub>1</sub> phase</a></li> <li><a href="/wiki/S_phase" title="S phase">S phase</a></li> <li><a href="/wiki/G2_phase" title="G2 phase">G<sub>2</sub> phase</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cell_division" title="Cell division">M phase</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Mitosis" title="Mitosis">Mitosis</a> (<a href="/wiki/Preprophase" title="Preprophase">Preprophase</a></li> <li><a href="/wiki/Prophase" title="Prophase">Prophase</a></li> <li><a href="/wiki/Prometaphase" title="Prometaphase">Prometaphase</a></li> <li><a href="/wiki/Metaphase" title="Metaphase">Metaphase</a></li> <li><a href="/wiki/Anaphase" title="Anaphase">Anaphase</a></li> <li><a href="/wiki/Telophase" title="Telophase">Telophase</a>)</li> <li><a href="/wiki/Cytokinesis" title="Cytokinesis">Cytokinesis</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cell_cycle_checkpoint" title="Cell cycle checkpoint">Cell cycle checkpoints</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Restriction_point" title="Restriction point">Restriction point</a></li> <li><a href="/wiki/Spindle_checkpoint" title="Spindle checkpoint">Spindle checkpoint</a></li> <li><a href="/wiki/Postreplication_checkpoint" title="Postreplication checkpoint">Postreplication checkpoint</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other cellular phases</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Apoptosis" title="Apoptosis">Apoptosis</a></li> <li><a href="/wiki/G0_phase" title="G0 phase">G<sub>0</sub> phase</a></li> <li><a href="/wiki/Meiosis" title="Meiosis">Meiosis</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table></div>    </div><noscript><img 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