Vaccines Development | Therapeutics

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height="136" alt="icon-and-you-mdd.jpg" loading="eager" title="icon-and-you-mdd.jpg" /> </div> </div> </div> <span class="h4">ICON and You</span> <p class="section-overview--desktop">Partners making a difference.</p> </a> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a href="/therapeutics" aria-expanded="false" class="nav-link dropdown-toggle" data-toggle="dropdown" role="button"> Therapeutics <span></span> </a> <div class="menu_link_content menu-link-contentmain view-mode-main-navigation dropdown-menu"> <button class="navbar-btn navbar-btn--back" type="button"> <span class="navbar-btn__icon"></span> </button> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-xl-3"> <div class="paragraph paragraph--type--mega-menu-text paragraph--view-mode--default"> <div class="mega-menu-title"><a href="/therapeutics" target="_self">Therapeutics</a></div> </div> <a class="dropdown-item" href="/therapeutics/cardiovascular">Cardiovascular</a> <a 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combination therapies requires appropriate obesity-specific trial designs, long-term follow-up studies and diverse patient recruitment.</p> </a> </div> <div class="col-xl-3"> <a href="/insights/therapeutics" class="dropdown-item dropdown-item--with-image"> <div class="image image--zoom-on-hover"> <div><div><img src="https://icon.widen.net/content/78559377-8cc3-4bc6-b6f2-cc20a04e1504/web/cells-menu-hero.jpg?crop=yes&w=260&h=136&itok=750H7OG2" width="260" height="136" alt="cells-menu-hero.jpg" loading="eager" title="cells-menu-hero.jpg" /> </div> </div> </div> <span class="h4">Therapeutics insights</span> <p class="section-overview--desktop">ICON's therapeutic experts contribute regularly to industry publications and the creation of thought leadership content. Read more. </p> </a> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a href="/insights" aria-expanded="false" class="nav-link dropdown-toggle" data-toggle="dropdown" role="button"> Insights <span></span> </a> <div class="menu_link_content menu-link-contentmain view-mode-main-navigation dropdown-menu"> <button class="navbar-btn navbar-btn--back" type="button"> <span class="navbar-btn__icon"></span> </button> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-xl-3"> <div class="paragraph paragraph--type--mega-menu-text paragraph--view-mode--default"> <div class="mega-menu-title"><a href="/insights" target="_self">Insights</a></div> </div> <a class="dropdown-item" href="/insights/digital-disruption">Digital Disruption</a> <a class="dropdown-item" href="/insights/patient-centricity">Patient Centricity</a> <a class="dropdown-item" href="/insights/regulatory-intelligence">Regulatory Intelligence</a> <a class="dropdown-item" 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efficient; the methods and technologies advancing Alzheimer’s and Parkinson’s R&D</span> <p class="section-overview--desktop">In this CNS whitepaper we examine how innovative methodologies and technologies are being implemented to improve the success rate of neurodegenerative clinical trials.</p> </a> </div> <div class="col-xl-3"> <a href="/sectors/biotech/early-phase-challenges-biotechs" class="dropdown-item dropdown-item--with-image"> <div class="image image--zoom-on-hover"> <div><div><img src="https://icon.widen.net/content/fc13f816-bd06-455c-a1ae-4daf6cb35f40/web/Thumbnail_biotech_whitepaper.jpeg?crop=yes&w=260&h=136&itok=XglqHZSI" width="260" height="136" alt="Early phase challenges for biotechs_whitepaper" loading="eager" title="Early phase challenges for biotechs_whitepaper" /> </div> </div> </div> <span class="h4">Early phase challenges for biotechs</span> <p class="section-overview--desktop">Approaching early phase trials strategically and anticipating obstacles can be critical to the later success of a therapeutic</p> </a> </div> <div class="col-xl-3"> <a href="/insights/regulatory-intelligence/exploring-fda-guidance-modern-data-monitoring-committees" class="dropdown-item dropdown-item--with-image"> <div class="image image--zoom-on-hover"> <div><div><img src="https://icon.widen.net/content/eaa349ef-9f6c-4c5c-b00f-e90cfc4bbedf/web/MDD_FDA_guidance_DMC.jpg?crop=yes&w=260&h=136&itok=KqupIbhv" width="260" height="136" alt="MDD_FDA_guidance_DMC.jpg" loading="eager" title="MDD_FDA_guidance_DMC.jpg" /> </div> </div> </div> <span class="h4">Exploring FDA guidance for modern Data Monitoring Committees</span> <p class="section-overview--desktop">What you need to know for compliant, efficient safety and efficacy monitoring</p> </a> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a href="/news-events" aria-expanded="false" class="nav-link dropdown-toggle" data-toggle="dropdown" role="button"> News & Events <span></span> </a> <div class="menu_link_content menu-link-contentmain view-mode-main-navigation dropdown-menu"> <button class="navbar-btn navbar-btn--back" type="button"> <span class="navbar-btn__icon"></span> </button> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-xl-3"> <div class="paragraph paragraph--type--mega-menu-text paragraph--view-mode--default"> <div class="mega-menu-title"><span class="h4">News & Events</span></div> <div class="section-overview--desktop"> <p>ICON regularly contributes thought leadership to industry media publications and conferences, and has been recognised as one of the world’s leading Contract Research Organisations through a number of high-profile industry awards.</p> </div> <a class="dropdown-item section-overview--desktop" href="/news-events">Read more</a> </div> </div> <div class="col-xl-3"> <div class="mega-menu-title"> </div> <a href="/news-events/press-releases" class="dropdown-item" data-drupal-link-system-path="node/33789">Press releases</a> <a href="/news-events/thought-leadership" class="dropdown-item" data-drupal-link-system-path="node/34266">In the News</a> <a href="/news-events/mediakit" class="dropdown-item" data-drupal-link-system-path="node/33787">Mediakit</a> <a href="/news-events/awards" class="dropdown-item" data-drupal-link-system-path="node/33778">Awards</a> <a href="/news-events/events" class="dropdown-item" data-drupal-link-system-path="node/34258">Events</a> <a href="/news-events/events/webinars" class="dropdown-item" data-drupal-link-system-path="node/34260">Webinars</a> <a href="/news-events/social-media" class="dropdown-item" data-drupal-link-system-path="node/33790">Social media</a> </div> <div class="col-xl-3"> <a href="/news-events/events/webinars/strategies-adc-bioanalysis" class="dropdown-item dropdown-item--with-image"> <div class="image image--zoom-on-hover"> <div><div><img src="https://icon.widen.net/content/eddc41a3-e26a-4b00-938f-7ba6fe776d32/web/Thumbnail_ACDs_webinar.jpg?crop=yes&w=260&h=136&itok=rTBCMcVB" width="260" height="136" alt="ACDs mollecule" loading="eager" title="ACDs mollecule" /> </div> </div> </div> <span class="h4">Strategies for ADC bioanalysis</span> <p class="section-overview--desktop">19 March 2025<br /> </p> </a> </div> <div class="col-xl-3"> <a href="/news-events/events/webinars/implementing-digital-health-technologies-patient-centred-trials" class="dropdown-item dropdown-item--with-image"> <div class="image image--zoom-on-hover"> <div><div><img src="https://icon.widen.net/content/deed9bfc-d284-4b69-bb2b-0622ed48952a/web/DHT_wearable_Thumbnail_1110x678px.jpg?crop=yes&w=260&h=136&itok=4hwkD-Ew" width="260" height="136" alt="DHT_wearable" loading="eager" title="DHT_wearable" /> </div> </div> </div> <span class="h4">Implementing digital health technologies for patient-centred trials</span> <p class="section-overview--desktop">25 March 2025</p> </a> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a href="/about" aria-expanded="false" class="nav-link dropdown-toggle" data-toggle="dropdown" role="button"> About ICON <span></span> </a> <div class="menu_link_content menu-link-contentmain view-mode-main-navigation dropdown-menu"> <button class="navbar-btn navbar-btn--back" type="button"> <span class="navbar-btn__icon"></span> </button> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-xl-3"> <div class="paragraph paragraph--type--mega-menu-text paragraph--view-mode--default"> <div class="mega-menu-title"><a href="/about" target="_self">About ICON</a></div> </div> <a class="dropdown-item" href="/about/company-history">Company history</a> <a class="dropdown-item" href="/about/icon-glance">ICON at a glance</a> <a class="dropdown-item" href="/about/healthcare-intelligence">Healthcare Intelligence</a> <a class="dropdown-item" href="/about/icon-in-asia-pacific">ICON in 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Evolved.</p> </a> </div> </div> </div> </div> </li> </ul> <ul region="primary_menu" class="navbar-nav navbar-nav-secondary"> <li class="nav-item"> <a href="https://careers.iconplc.com/" class="nav-link" target="_blank">Careers</a> </li> <li class="nav-item"> <a href="http://investor.iconplc.com/" class="nav-item-separator nav-link" target="_blank">Investors</a> </li> <li class="nav-item"> <a href="/contact" class="nav-item-separator nav-link" target="_self" data-drupal-link-system-path="node/33596">Contact</a> </li> <li class="nav-item"> <a href="https://iconplc.co.jp/" class="nav-link" target="_blank">日本語</a> </li> <li class="nav-item"> <a href="https://china.iconplc.com/" class="nav-link nav-item-separator" target="_blank">简体中文</a> </li> <li class="nav-item d-none d-xl-block"> <a class="nav-link" data-toggle="modal" href="#search-modal"> <i aria-hidden="true" class="icon-ui-search-loupe"></i> </a> </li> </ul> </div> <div class="navbar-revealer"></div> </div> <div class="navigation-backdrop fade"></div> </nav> </header> <div class="region region-highlighted"> <div data-drupal-messages-fallback class="hidden"></div> </div> <main role="main"> <a id="main-content" tabindex="-1"></a> <div class="layout-content"> <div class="region region-content"> <div id="block-iconplc-content"> <article> <div> <div class="layout layout--onecol"> <div class="layout__region layout__region--content"> <div id="7bcbde80-879e-49d6-aeb3-2e5c1e74f871" class="promo--wrapper"> <div class="breadcrumb-wrapper "> <ol class="breadcrumb"> <li class="breadcrumb-item"> <a href="/" class="breadcrumb__link">Home</a> </li> <li class="breadcrumb-item"> <a href="/therapeutics" class="breadcrumb__link">Therapeutics</a> </li> <li class="breadcrumb-item"> Vaccines </li> </ol> </div> <div> <div class="promo promo--subpage" data-title="Vaccines"> <div class="promo__content"> <div class="promo__image-overlay promo__image-overlay--gray-light"></div> <div title="ICON Vaccines Development" data-responsive-backgrounds="true" data-responsive-background-lg="https://icon.widen.net/content/1cccad98-7dc6-45d8-bf98-51db5eac574c/web/Vaccines-landing-page-banners-cell%20green.jpg?crop=yes&w=1920&h=507&a=0,0&itok=sT9CYDQr" data-responsive-background-md="https://icon.widen.net/content/1cccad98-7dc6-45d8-bf98-51db5eac574c/web/Vaccines-landing-page-banners-cell%20green.jpg?crop=yes&w=1895&h=600&a=25,0&itok=M_eBdqz2" data-responsive-background-sm="https://icon.widen.net/content/1cccad98-7dc6-45d8-bf98-51db5eac574c/web/Vaccines-landing-page-banners-cell%20green.jpg?crop=yes&w=1566&h=600&a=354,0&itok=jE2dXvqM" data-responsive-background-xs="https://icon.widen.net/content/1cccad98-7dc6-45d8-bf98-51db5eac574c/web/Vaccines-landing-page-banners-cell%20green.jpg?crop=yes&w=402&h=600&a=1156,0&itok=fAxFZDWt" class="promo__image-container"></div> <div class="promo__text-container"> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-md-9"> <h1>Vaccines</h1> <p class="lead">ICON has lead the development of 18 vaccines resulting in FDA/EMA approvals, including the world’s first approved vaccine for COVID-19.</p> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="container-fluid container-fluid--xl"> <div class="row no-gutters"> <div class="col-md-9 order-2"> <section class="main-content"> <div class="content-box sidebar-content"> <div id="39131a35-b614-45e4-a695-e440b576afc7"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h2>We work with global biotech, pharma, government and NGOs in the design, execution, and commercialisation of vaccines to prevent infectious diseases.</h2> <h3> </h3> <div><p>The number of new and re-emerging infectious diseases continues to rise and pose a threat to world health. Our global team have built up extensive vaccine expertise, with over 200 years experience across our leadership team alone. This enables us to anticipate the challenges in your drug development plan and consistently beat aggressive vaccine start up timelines and enrolment goals. We are applying this experience to the COVID-19 vaccine trials we are currently running. We focus on driving your milestone success and on providing high quality deliverables within budget.</p><p>Our work has resulted in 18 vaccine approvals by the United States (US) Food and Drug Administration (FDA) and the European Medicines Agency (EMA). And our team have winners of “Best CRO” at the Vaccine Industry Excellence (ViE) <a href="/news-events/awards/" target="_self">Awards</a> three times (2020, 2017 and 2014) and have been named a finalist every year since 2011.</p><p>We are also prime contractors for the US Government and qualified provider for the <a href="https://www.gatesfoundation.org/" target="_blank">Bill and Melinda Gates Medical Research Institute</a>. Our broad portfolio of services and global footprint also serve the needs of other global health organisations such as <a href="https://wellcome.ac.uk/" target="_blank">Wellcome Trust</a>, <a href="https://www.theglobalfund.org/" target="_blank">Global Fund</a> and <a href="https://cepi.net/" target="_blank">CEPI</a>.</p></div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="d84b3599-6171-4aea-90c1-c2841c02e40f" class="icon-group icon-group--horizontal"> <div class="container-fluid container-fluid--xl"> <ul class="icon-group__items icon-group__items__columns-3"> <li class="icon-group__item--blue"> <div lang="en" class="icon-group__wrapper" > <i class="icon-notes"></i> <p class="mb-2 icons-large-text">194+</p> <small>Studies conducted</small> </div> </li> <li class="icon-group__item--green-bright"> <div lang="en" class="icon-group__wrapper" > <i class="icon-partnership-2"></i> <p class="mb-2 icons-large-text">405,750</p> <small>Patients involved</small> </div> </li> <li class="icon-group__item--blue-light"> <div lang="en" class="icon-group__wrapper" > <i class="icon-global"></i> <p class="mb-2 icons-large-text">5,800+</p> <small>Sites worldwide</small> </div> </li> </ul> </div> </div> <div id="2338ed3c-08c1-4954-90ff-c0e559b4bbf4"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> Experience our partners can trust </h3> <div><p>Our team understands the urgency, complexities, and potential challenges associated with running trials in normal times. During this pandemic we are running over 130 <a href="https://www.iconplc.com/insights/therapeutics/infectious-diseases/covid-19-vaccine-trials" target="_self">COVID-19 trials </a>and have extensive prophylactic vaccine study experience. ICON provided clinical trial services to the <a href="/news-events/press-releases/icon-pfizer-biontech/" target="_self">Pfizer and BioNTech SE investigational COVID-19 vaccine programme</a>. We make data-driven recommendations and apply <a href="/solutions/clinical-and-scientific-operations/covid-19/treatment-vaccine-trials/" target="_self">best practices to execute your COVID-19 study</a>, while safeguarding trial participants. By selecting us as your contract research organisation (CRO) partner, you will benefit from:</p><ul><li>A leadership team focused specifically in Vaccines with well over 100 years of combined experience in vaccine clinical development who provide insight into your protocol and strategies to operationalize execution</li><li>Direct involvement in the design, implementation and / or execution of clinical trials</li><li>Specialized, scalable infectious disease and vaccine-experienced resources ready to deploy for COVID-19 studies</li><li><a href="/solutions/site-and-patient-solutions/clinical-site-solutions/" target="_self">Global Site Networ</a>k and <a href="/solutions/site-and-patient-solutions/" target="_self">Patient Solutions</a> comprised of ICON’s proprietary vaccine-experienced sites with PBMC isolation capabilities that are prepared to conduct <a href="/solutions/clinical-and-scientific-operations/covid-19/treatment-vaccine-trials/" target="_self">COVID-19 vaccine trials</a></li><li><a href="/solutions/technologies/firecrest/" target="_self">FIRECREST digital solutions</a> including an Investigator Portal for document distribution and protocol-specific training for site staff</li></ul></div> </div> </div> </div> </div> </div> </div> </div> </div><div id="2af9349d-acd5-4002-b308-a0f7e90162c6"> <div> <div class="file file--with-thumbnail"> <div class="container-fluid container-fluid--xl"> <a href="/insights/therapeutics/infectious-diseases/covid-19-vaccines-pass" target="_self" title="COVID-19 vaccines: Post-authorisation safety surveillance"> <span class="file__thumbnail"> <div> <div><div><img src="https://icon.widen.net/content/adc13667-27e5-4bf6-88f2-74481ec8d9df/web/covid-19-vaccines.png?h=240&itok=lZr8Plsv" width="170" height="240" alt="covid-19-vaccines.png" loading="lazy" title="covid-19-vaccines.png" /> </div> </div> </div> </span> <span class="file__details"> <h3>COVID-19 vaccines: Post-authorisation safety surveillance</h3> <p>This whitepaper explores the multifaceted challenges of COVID-19 post-authorisation safety surveillance studies and how business intelligence tools can benefit these efforts. </p> </span> </a> </div> </div> </div> </div> <div id="ece61238-4ab0-4eed-8909-8527ef624e02"> <div> <div class="file file--with-thumbnail"> <div class="container-fluid container-fluid--xl"> <a href="/insights/therapeutics/infectious-diseases/hiv" target="_self" title="The evolution of HIV treatments: From antiretroviral therapy to vaccines, where we are today and what’s next"> <span class="file__thumbnail"> <div> <div><div><img src="https://icon.widen.net/content/6a2e203d-1a81-4d53-93fb-767058b31f03/web/11484-HIV-Whitepaper_thumbnail.jpg?h=240&itok=tMNZ9x8c" width="170" height="240" alt="11484-HIV-Whitepaper_thumbnail.jpg" loading="lazy" title="11484-HIV-Whitepaper_thumbnail.jpg" /> </div> </div> </div> </span> <span class="file__details"> <h3>The evolution of HIV treatments: From antiretroviral therapy to vaccines, where we are today and what’s next</h3> <p>This whitepaper looks at the significant advancements in the management of human immunodeficiency virus (HIV) over the past decade and where treatment is going in the decade ahead</p> </span> </a> </div> </div> </div> </div> <div id="28e24fa8-2238-45ba-85ae-8623c55dabb7"> <div> <div class="file file--with-thumbnail"> <div class="container-fluid container-fluid--xl"> <a href="/insights/therapeutics/infectious-diseases/covid-19-vaccine-trials" target="_self" title="Whitepaper: Pandemic respiratory vaccine clinical trials: A departure from business as usual"> <span class="file__thumbnail"> <div> <div><div><img src="https://icon.widen.net/content/ca01b175-7389-48cd-b6c4-708849d40d3c/web/uuid_d8792750-a3cf-44c8-94dc-a4e7d69050fd_vaccines-covid19.jpg?h=240&itok=dRul633P" width="170" height="240" alt="uuid_d8792750-a3cf-44c8-94dc-a4e7d69050fd_vaccines-covid19.jpg" loading="lazy" title="uuid_d8792750-a3cf-44c8-94dc-a4e7d69050fd_vaccines-covid19.jpg" /> </div> </div> </div> </span> <span class="file__details"> <h3>Whitepaper: Pandemic respiratory vaccine clinical trials: A departure from business as usual</h3> <p>Focus on the corresponding success factors that can keep pandemic respiratory vaccine trials running at optimal speed and efficiency.</p> </span> </a> </div> </div> </div> </div> <div id="7a4dc931-8b70-4883-b5b4-b2b077be6b6c"> <div> <div class="file file--with-thumbnail"> <div class="container-fluid container-fluid--xl"> <a href="https://www2.iconplc.com/factsheet_Vaccines" target="_blank" title="Factsheet: Vaccines"> <span class="file__thumbnail"> <div> <div><div><img src="https://icon.widen.net/content/fe5e398b-4717-49ee-b977-18b1044036e2/web/vaccine-congress-rapid-mobilsation.png?h=240&itok=u7TLEFq2" width="170" height="240" alt="vaccine-congress-rapid-mobilsation.png" loading="lazy" title="vaccine-congress-rapid-mobilsation.png" /> </div> </div> </div> </span> <span class="file__details"> <h3>Factsheet: Vaccines</h3> <p>Rapid mobilisation advancing vaccine development. </p> </span> </a> </div> </div> </div> </div> <div id="edcb0ef1-1473-4777-9156-e2aa455503f0"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> Vaccines experience & capabilities </h3> <div> <p>Our vaccine research experience encompasses prophylaxes for seasonal, vector, sexually-transmitted, enteric and other viral and bacterial infections across all populations including maternal participants.</p> <p><strong>Vaccine types </strong></p> <table border="0" cellpadding="1" cellspacing="1" style="width: 100%;"> <tbody> <tr> <td style="width: 50%; vertical-align: top;"> <ul> <li>Live-attenuated vaccines</li> <li>Inactivated vaccines</li> <li>Mono, polyvalent, and combination vaccines</li> <li>Subunit, recombinant, polysaccharide, & conjugate vaccines</li> </ul> </td> <td style="vertical-align: top;"> <ul> <li>DNA vaccines</li> <li>Recombinant vector</li> <li>Vaccines (platform-based)</li> <li>mRNA Toxoid vaccines</li> </ul> </td> </tr> </tbody> </table> <p><br> Watch the videos below for an overview of ICON's experience and capabilities in vaccines, including details of vaccine types, participant populations and indications, as well as the range of our services.</p> </div> </div> </div> </div> </div> </div> </div> </div> </div><div id="c26ff68f-8f1b-4516-a868-a7f79d366ff5"> <div class="container-fluid container-fluid--xl"> <div class="video-player video-player--with-playlist"> <video id="player-1660310604482435696" data-playlist-id="1660310604482435696" data-account="108289197001" data-player="default" data-embed="default" data-application-id="" class="video-js" controls=""> </video> <script src="//players.brightcove.net/108289197001/default_default/index.min.js"></script> <div class="vjs-playlist"></div> <script src="https://players.brightcove.net/videojs-bc-playlist-ui/3/videojs-bc-playlist-ui.min.js"></script> <script type="text/javascript"> videojs.getPlayer('player-1660310604482435696').ready(function() { // Get a reference to the player var myPlayer = this, // Create an object in which you will place options options = {}; // Set options options.horizontal = true; options.autoadvance = 0; // Call plugins method passing in options object myPlayer.bcPlaylistUi(options); }); </script> <div class="video-label"></div> </div> </div> </div> <div id="5e6e3c8d-b46f-4321-bb0c-ae0786b5d1c0"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> Our Vaccines service offerings </h3> <div><p>Our extensive services include:</p><ul><li><a href="/solutions/clinical-and-scientific-operations/" target="_self">Clinical monitoring and study management</a> </li><li><a href="/solutions/consulting/" target="_self">Expert consultation</a> and operational delivery Phase I-IV</li><li>Life cycle management and <a href="/solutions/consulting/commercial-positioning-consulting/patient-reported-outcomes/">outcomes research protocol development</a></li><li><a href="/solutions/consulting/regulatory-affairs-consulting/" target="_self">Regulatory consultancy with phase specific quality systems</a></li><li><a href="/solutions/clinical-and-scientific-operations/medical-affairs/" target="_self">Medical affairs</a> and <a href="/solutions/clinical-and-scientific-operations/pharmacovigilance/" target="_self">pharmacovigilance</a></li><li><a href="/solutions/clinical-and-scientific-operations/data-management/" target="_self">Data management</a> and <a href="/solutions/clinical-and-scientific-operations/biostatistics/" target="_self">biostatistics</a></li><li><a href="/sectors/government-and-public-health/" target="_self">Vaccine government experience</a></li><li><a href="/solutions/site-and-patient-solutions/global-recruitment-solutions/patient-recruitment/" target="_self">Patient recruitment</a></li></ul></div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="4ba22a52-0052-4cf1-8b28-9027deb8ece1"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> Accellacare, ICON's Global Site Network </h3> <div> <p><a href="http://www.accellacare.com" target="_blank">Accellacare</a>, ICON's Global Site Network combines our proprietary site network and healthcare alliance sites across North America, Europe, Africa and Middle East to provide greater access to patients and multi-specialty physicians for our clients. This network of research sites, offers proven, professional clinical research resources and infrastructure for your clinical research.</p> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="3b16fa40-387f-4eab-8331-c3c4c8cf6b47"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> Adaptive design trials </h3> <div> <p>We are the only full service CRO with the knowledge, software, systems, and global footprint to make <a href="/solutions/consulting/asset-development/adaptive-trials/" target="_self">adaptive clinical trials</a> a reality. Our full service includes the design, simulation, and execution of adaptive clinical trials that can be effectively applied in these studies.</p> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="ba94673e-ee8d-43ff-8b26-21bd6c427c31"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> Digital solutions for education and automation to increase efficiency in clinical trials </h3> <div> <p><a href="/solutions/technologies/firecrest/" target="_self">FIRECREST digital solutions</a> provide you with the tools and support to move your training on line - whether it is the training that you would usually deliver in group meetings or the training that CRAs provide on site.   </p> <p>The FIRECREST Study Portal, which is fully customisable to your study, provides single sign-on to a range of education and automation solutions. Connectivity to site and study staff will lead to increased engagement and improved study performance.</p> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="bde7427d-967f-414d-b219-cec6c166d9d3"> <div class="bg-gray"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper "> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h2>Infectious diseases and vaccines insights</h2> <h3> </h3> <div> <p>ICON's Infectious Diseases and Vaccines teams contribute regularly to media and industry conversations in addition to the production of thought leadership content in the form of whitepapers and blogs.</p> </div> <a class="btn btn-primary btn-md" href="/insights/therapeutics/infectious-diseases" target="_self">Read more </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </second> </div> <div class="col-md-3 order-1"> <div id="01868218-273f-4b5d-8ddd-71a330f8b4b4"> <div class="container-fluid container-fluid--xl sidebar-menu-wrapper"> <div class="sidebar"> <div class="sidebar sidebar--sticky sidebar--collapsible"> <a class="sidebar--collapsible__toggle collapsed" role="button" data-toggle="collapse" href="#sidebar-content" aria-expanded="false" aria-controls="sidebar-content"> <span>In this section</span> </a> <div class="sidebar--collapsible__content collapse" id="sidebar-content"> <div class="sidebar--menu"> <h6 class="d-none d-md-block">In this section</h6> <ul class="sidebar--collapsible__list"> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#biosimilars-10484"></span> <a href="/therapeutics/biosimilars" data-drupal-link-system-path="node/33807">Biosimilars</a> <div class="collapse " id="biosimilars-10484" > <ul class="menu menu-level-1"> <li> <a href="/therapeutics/biosimilars/clinical-trial-development-planning" data-drupal-link-system-path="node/41861">Clinical trial development planning</a> <div class="collapse " id="biosimilars-clinical-trial-development-planning-11671" > </div> </li> </ul> </div> </li> <li> <a href="/therapeutics/cardiovascular" title="ICON has extensive experience in cardiovascular clinical research trials across the entire drug development spectrum." data-drupal-link-system-path="node/34066">Cardiovascular</a> <div class="collapse " id="cardiovascular-10511" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#cell-and-gene-therapies-10512"></span> <a href="/therapeutics/cell-and-gene-therapies" data-drupal-link-system-path="node/34067">Cell and Gene Therapies</a> <div class="collapse " id="cell-and-gene-therapies-10512" > <ul class="menu menu-level-1"> <li> <a href="/insights/value-based-healthcare/the-affordability-hurdle-for-gene-therapies" data-drupal-link-system-path="node/33755">The affordability hurdle for gene therapies</a> <div class="collapse " id="cell-and-gene-therapies-the-affordability-hurdle-for-gene-therapies-10513" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#central-nervous-system-10514"></span> <a href="/therapeutics/central-nervous-system" data-drupal-link-system-path="node/34071">Central Nervous System</a> <div class="collapse " id="central-nervous-system-10514" > <ul class="menu menu-level-1"> <li> <a href="/therapeutics/central-nervous-system/cns-neurology" data-drupal-link-system-path="node/34068">CNS Neurology</a> <div class="collapse " id="central-nervous-system-cns-neurology-10515" > </div> </li> <li> <a href="/therapeutics/central-nervous-system/cns-pain" data-drupal-link-system-path="node/34069">CNS Pain</a> <div class="collapse " id="central-nervous-system--cns-pain-10516" > </div> </li> <li> <a href="/therapeutics/central-nervous-system/cns-psychiatry" data-drupal-link-system-path="node/34070">CNS Psychiatry</a> <div class="collapse " id="central-nervous-system---cns-psychiatry-10517" > </div> </li> <li> <a href="/insights/therapeutics/central-nervous-system/challenges-and-opportunities-in-traumatic-brain-injury-clinical-trials" data-drupal-link-system-path="node/33678">Challenges and opportunities in traumatic brain injury clinical trials</a> <div class="collapse " id="central-nervous-system----challenges-and-opportunities-in-traumatic-brain-injury-clinical-trials-10518" > </div> </li> <li> <a href="/insights/therapeutics/central-nervous-system/key-considerations-for-parkinsons-disease-trials" data-drupal-link-system-path="node/33680">Challenges and opportunities in Parkinson’s Disease clinical trials</a> <div class="collapse " id="central-nervous-system-----challenges-and-opportunities-in-parkinson-s-disease-clinical-trials-10519" > </div> </li> <li> <a href="/insights/therapeutics/central-nervous-system/key-considerations-in-chronic-pain-clinical-trials" data-drupal-link-system-path="node/33681">Key considerations in chronic pain clinical trials</a> <div class="collapse " id="central-nervous-system------key-considerations-in-chronic-pain-clinical-trials-10520" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#endocrine-metabolic-disorders-10521"></span> <a href="/therapeutics/endocrine-metabolic-disorders" data-drupal-link-system-path="node/34072">Endocrine & Metabolic Disorders</a> <div class="collapse " id="endocrine-metabolic-disorders-10521" > <ul class="menu menu-level-1"> <li> <a href="/therapeutics/endocrine-metabolic-disorders/obesity" data-drupal-link-system-path="node/38991">Obesity</a> <div class="collapse " id="endocrine-metabolic-disorders-obesity-11021" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#endocrine-metabolic-disorders--metabolic-dysfunction-associated-steatohepatitis-mash--10522"></span> <a href="/therapeutics/endocrine-metabolic-disorders/non-alcoholic-steatohepatitis-nash" data-drupal-link-system-path="node/34073">Metabolic dysfunction-associated steatohepatitis (MASH)</a> <div class="collapse " id="endocrine-metabolic-disorders--metabolic-dysfunction-associated-steatohepatitis-mash--10522" > <ul class="menu menu-level-2"> <li> <a href="/insights/therapeutics/nash/the-voice-of-nash-investigators-in-patient-recruitment" data-drupal-link-system-path="node/33694">The voice of NASH investigators</a> <div class="collapse " id="metabolic-dysfunction-associated-steatohepatitis-mash--the-voice-of-nash-investigators-10523" > </div> </li> </ul> </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#infectious-diseases-10524"></span> <a href="/therapeutics/infectious-diseases" data-drupal-link-system-path="node/34076">Infectious Diseases</a> <div class="collapse " id="infectious-diseases-10524" > <ul class="menu menu-level-1"> <li> <a href="/insights/therapeutics/infectious-diseases/antimicrobial-resistance" data-drupal-link-system-path="node/33685">Antimicrobial resistance</a> <div class="collapse " id="infectious-diseases-antimicrobial-resistance-10525" > </div> </li> <li> <a href="/insights/therapeutics/infectious-diseases/hiv" data-drupal-link-system-path="node/33689">HIV</a> <div class="collapse " id="infectious-diseases--hiv-10526" > </div> </li> <li> <a href="/insights/therapeutics/infectious-diseases/covid-19-vaccine-trials" data-drupal-link-system-path="node/33687">Pandemic respiratory vaccine clinical trials</a> <div class="collapse " id="infectious-diseases---pandemic-respiratory-vaccine-clinical-trials-10527" > </div> </li> </ul> </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#internal-medicine-immunology-10528"></span> <a href="/therapeutics/internal-medicine-immunology" data-drupal-link-system-path="node/34080">Internal Medicine & Immunology</a> <div class="collapse " id="internal-medicine-immunology-10528" > <ul class="menu menu-level-1"> <li> <a href="/therapeutics/internal-medicine-and-immunology/dermatology" data-drupal-link-system-path="node/34077">Dermatology</a> <div class="collapse " id="internal-medicine-immunology-dermatology-10529" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#internal-medicine-immunology--gastrointestinal-10530"></span> <a href="/therapeutics/internal-medicine-immunology/gastrointestinal" data-drupal-link-system-path="node/34078">Gastrointestinal</a> <div class="collapse " id="internal-medicine-immunology--gastrointestinal-10530" > <ul class="menu menu-level-2"> <li> <a href="/therapeutics/internal-medicine-and-immunology/gastrointestinal/inflammatory-bowel-disease" data-drupal-link-system-path="node/34079">Inflammatory Bowel Disease</a> <div class="collapse " id="gastrointestinal-inflammatory-bowel-disease-10531" > </div> </li> </ul> </div> </li> <li> <a href="/therapeutics/internal-medicine-immunology/ophthalmology" data-drupal-link-system-path="node/34081">Ophthalmology</a> <div class="collapse " id="internal-medicine-immunology---ophthalmology-10532" > </div> </li> <li> <a href="/therapeutics/internal-medicine-immunology/respiratory" data-drupal-link-system-path="node/34082">Respiratory</a> <div class="collapse " id="internal-medicine-immunology----respiratory-10533" > </div> </li> <li> <a href="/therapeutics/internal-medicine-immunology/rheumatology" data-drupal-link-system-path="node/34083">Rheumatology</a> <div class="collapse " id="internal-medicine-immunology-----rheumatology-10534" > </div> </li> <li> <a href="/therapeutics/internal-medicine-immunology/transplant-immunology" data-drupal-link-system-path="node/34091">Transplant Immunology</a> <div class="collapse " id="internal-medicine-immunology------transplant-immunology-10544" > </div> </li> <li> <a href="/therapeutics/internal-medicine-and-immunology/urology" data-drupal-link-system-path="node/34084">Urology</a> <div class="collapse " id="internal-medicine-immunology-------urology-10535" > </div> </li> </ul> </div> </li> <li> <a href="/therapeutics/medical-device" data-drupal-link-system-path="node/34085">Medical Device</a> <div class="collapse " id="medical-device-10536" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#oncology-10537"></span> <a href="/therapeutics/oncology" data-drupal-link-system-path="node/34088">Oncology</a> <div class="collapse " id="oncology-10537" > <ul class="menu menu-level-1"> <li> <a href="/therapeutics/oncology/early-phase-oncology" data-drupal-link-system-path="node/34086">Early Phase Oncology</a> <div class="collapse " id="oncology-early-phase-oncology-10538" > </div> </li> <li> <a href="/therapeutics/oncology/immuno-oncology" data-drupal-link-system-path="node/34087">Immuno-Oncology</a> <div class="collapse " id="oncology--immuno-oncology-10539" > </div> </li> </ul> </div> </li> <li> <a href="/therapeutics/pediatrics" data-drupal-link-system-path="node/34089">Pediatrics</a> <div class="collapse " id="pediatrics-10540" > </div> </li> <li class="sidebar--submenu"> <span aria-controls="sidebar-content" class="collapsed " data-toggle="collapse" role="button" href="#rare-orphan-diseases-10541"></span> <a href="/therapeutics/rare-orphan-diseases" data-drupal-link-system-path="node/34090">Rare & Orphan Diseases</a> <div class="collapse " id="rare-orphan-diseases-10541" > <ul class="menu menu-level-1"> <li> <a href="/insights/therapeutics/rare-and-orphan-diseases/leveraging-historical-data-for-use-in-rare-disease-trials" data-drupal-link-system-path="node/33707">Leveraging historical data for use in rare disease trials</a> <div class="collapse " id="rare-orphan-diseases-leveraging-historical-data-for-use-in-rare-disease-trials-10542" > </div> </li> <li> <a href="/insights/therapeutics/rare-and-orphan-diseases/patient-centricity-in-orphan-drug-development" data-drupal-link-system-path="node/33709">Patient centricity in orphan drug development</a> <div class="collapse " id="rare-orphan-diseases--patient-centricity-in-orphan-drug-development-10543" > </div> </li> </ul> </div> </li> <li 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