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(PDF) BMC Evolutionary Biology Phenotypic novelty in experimental hybrids is predicted by the genetic distance between species of cichlid fish | Oliver Selz and ole seehausen - Academia.edu
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A previously experimentally untested prediction is that the amount of transgression" /> <meta property="article:author" content="https://independent.academia.edu/OliverSelz" /> <meta property="article:author" content="https://independent.academia.edu/oleseehausen" /> <meta name="description" content="Background: Transgressive segregation describes the occurrence of novel phenotypes in hybrids with extreme trait values not observed in either parental species. A previously experimentally untested prediction is that the amount of transgression" /> <title>(PDF) BMC Evolutionary Biology Phenotypic novelty in experimental hybrids is predicted by the genetic distance between species of cichlid fish | Oliver Selz and ole seehausen - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/30069410/BMC_Evolutionary_Biology_Phenotypic_novelty_in_experimental_hybrids_is_predicted_by_the_genetic_distance_between_species_of_cichlid_fish" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = '92477ec68c09d28ae4730a4143c926f074776319'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1732786929000); window.Aedu.timeDifference = new Date().getTime() - 1732786929000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Background: Transgressive segregation describes the occurrence of novel phenotypes in hybrids with extreme trait values not observed in either parental species. A previously experimentally untested prediction is that the amount of transgression increases with the genetic distance between hybridizing species. This follows from QTL studies suggesting that transgression is most commonly due to complementary gene action or epistasis, which become more frequent at larger genetic distances. This is because the number of QTLs fixed for alleles with opposing signs in different species should increase with time since speciation provided that speciation is not driven by disruptive selection. We measured the amount of transgression occurring in hybrids of cichlid fish bred from species pairs with gradually increasing genetic distances and varying phenotypic similarity. Transgression in multi-trait shape phenotypes was quantified using landmark-based geometric morphometric methods.","author":[{"@context":"https://schema.org","@type":"Person","name":"Oliver Selz"},{"@context":"https://schema.org","@type":"Person","name":"ole seehausen"}],"contributor":[{"@context":"https://schema.org","@type":"Person","name":"ole seehausen"}],"dateCreated":"2016-11-24","dateModified":"2017-06-02","datePublished":null,"headline":"BMC Evolutionary Biology Phenotypic novelty in experimental hybrids is predicted by the genetic distance between species of cichlid fish","inLanguage":"en","keywords":["Speciation","Hybridization","Cichlidae","Cichlids Fishes"],"locationCreated":null,"publication":null,"publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"image":null,"thumbnailUrl":null,"url":"https://www.academia.edu/30069410/BMC_Evolutionary_Biology_Phenotypic_novelty_in_experimental_hybrids_is_predicted_by_the_genetic_distance_between_species_of_cichlid_fish","sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}]}</script><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/single_work_page/loswp-102fa537001ba4d8dcd921ad9bd56c474abc201906ea4843e7e7efe9dfbf561d.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/body-8d679e925718b5e8e4b18e9a4fab37f7eaa99e43386459376559080ac8f2856a.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/button-3cea6e0ad4715ed965c49bfb15dedfc632787b32ff6d8c3a474182b231146ab7.css" /><link rel="stylesheet" media="all" 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A previously experimentally untested prediction is that the amount of transgression increases with the genetic distance between hybridizing species. This follows from QTL studies suggesting that transgression is most commonly due to complementary gene action or epistasis, which become more frequent at larger genetic distances. This is because the number of QTLs fixed for alleles with opposing signs in different species should increase with time since speciation provided that speciation is not driven by disruptive selection. We measured the amount of transgression occurring in hybrids of cichlid fish bred from species pairs with gradually increasing genetic distances and varying phenotypic similarity. 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A previously experimentally untested prediction is that the amount of transgression increases with the genetic distance between hybridizing species. This follows from QTL studies suggesting that transgression is most commonly due to complementary gene action or epistasis, which become more frequent at larger genetic distances. This is because the number of QTLs fixed for alleles with opposing signs in different species should increase with time since speciation provided that speciation is not driven by disruptive selection. We measured the amount of transgression occurring in hybrids of cichlid fish bred from species pairs with gradually increasing genetic distances and varying phenotypic similarity. Transgression in multi-trait shape phenotypes was quantified using landmark-based geometric morphometric methods.</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--work-card","attachmentId":50518521,"attachmentType":"pdf","workUrl":"https://www.academia.edu/30069410/BMC_Evolutionary_Biology_Phenotypic_novelty_in_experimental_hybrids_is_predicted_by_the_genetic_distance_between_species_of_cichlid_fish"}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--work-card","attachmentId":50518521,"attachmentType":"pdf","workUrl":"https://www.academia.edu/30069410/BMC_Evolutionary_Biology_Phenotypic_novelty_in_experimental_hybrids_is_predicted_by_the_genetic_distance_between_species_of_cichlid_fish"}"><span class="material-symbols-outlined" style="font-size: 20px" 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style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="120317220" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/120317220/Hybrid_Breakdown_in_Cichlid_Fish">Hybrid Breakdown in Cichlid Fish</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="7541539" href="https://independent.academia.edu/oleseehausen">ole seehausen</a></div><p class="ds-related-work--metadata ds2-5-body-xs">PLOS ONE, 2015</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Hybrid Breakdown in Cichlid Fish","attachmentId":115507464,"attachmentType":"pdf","work_url":"https://www.academia.edu/120317220/Hybrid_Breakdown_in_Cichlid_Fish","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/120317220/Hybrid_Breakdown_in_Cichlid_Fish"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="13706089" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/13706089/Behavioural_isolation_may_facilitate_homoploid_hybrid_speciation_in_cichlid_fish">Behavioural isolation may facilitate homoploid hybrid speciation in cichlid fish</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32839171" href="https://rug.academia.edu/MartineMaan">Martine Maan</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="7541539" href="https://independent.academia.edu/oleseehausen">ole seehausen</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Evolutionary Biology, 2014</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Behavioural isolation may facilitate homoploid hybrid speciation in cichlid fish","attachmentId":45033895,"attachmentType":"pdf","work_url":"https://www.academia.edu/13706089/Behavioural_isolation_may_facilitate_homoploid_hybrid_speciation_in_cichlid_fish","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/13706089/Behavioural_isolation_may_facilitate_homoploid_hybrid_speciation_in_cichlid_fish"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="28293221" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/28293221/Genetic_linkage_of_distinct_adaptive_traits_in_sympatrically_speciating_crater_lake_cichlid_fish">Genetic linkage of distinct adaptive traits in sympatrically speciating crater lake cichlid fish</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="25663965" href="https://muni.academia.edu/VieraKovacova">Viera Kovacova</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="8742" href="https://qut.academia.edu/CarmeloFruciano">Carmelo Fruciano</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Our understanding of how biological diversity arises is limited, especially in the case of speciation in the face of gene flow. Here we investigate the genomic basis of adaptive traits, focusing on a sympatrically diverging species pair of crater lake cichlid fishes. We identify the main quantitative trait loci (QTL) for two eco-morphological traits: body shape and phar-yngeal jaw morphology. These traits diverge in parallel between benthic and limnetic species in the repeated adaptive radiations of this and other fish lineages. Remarkably, a single chromosomal region contains the highest effect size QTL for both traits. Transcriptomic data show that the QTL regions contain genes putatively under selection. Independent population genomic data corroborate QTL regions as areas of high differentiation between the sympatric sister species. Our results provide empirical support for current theoretical models that emphasize the importance of genetic linkage and pleiotropy in facilitating rapid divergence in sympatry.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Genetic linkage of distinct adaptive traits in sympatrically speciating crater lake cichlid fish","attachmentId":48625053,"attachmentType":"pdf","work_url":"https://www.academia.edu/28293221/Genetic_linkage_of_distinct_adaptive_traits_in_sympatrically_speciating_crater_lake_cichlid_fish","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/28293221/Genetic_linkage_of_distinct_adaptive_traits_in_sympatrically_speciating_crater_lake_cichlid_fish"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="107969073" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/107969073/Introgressive_hybridization_in_a_trophically_polymorphic_cichlid">Introgressive hybridization in a trophically polymorphic cichlid</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="171988268" href="https://konstanz.academia.edu/DarrinHulsey">Darrin Hulsey</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Ecology and Evolution, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Introgressive hybridization in a trophically polymorphic cichlid","attachmentId":106481569,"attachmentType":"pdf","work_url":"https://www.academia.edu/107969073/Introgressive_hybridization_in_a_trophically_polymorphic_cichlid","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/107969073/Introgressive_hybridization_in_a_trophically_polymorphic_cichlid"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="13561158" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/13561158/Environmental_variation_hybridization_and_phenotypic_diversification_in_Cuatro_Ci%C3%A9negas_pupfishes">Environmental variation, hybridization, and phenotypic diversification in Cuatro Ciénegas pupfishes</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32744490" href="https://independent.academia.edu/EvanCarson1">Evan Carson</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Evolutionary Biology, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Environmental variation, hybridization, and phenotypic diversification in Cuatro Ciénegas pupfishes","attachmentId":45214267,"attachmentType":"pdf","work_url":"https://www.academia.edu/13561158/Environmental_variation_hybridization_and_phenotypic_diversification_in_Cuatro_Ci%C3%A9negas_pupfishes","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/13561158/Environmental_variation_hybridization_and_phenotypic_diversification_in_Cuatro_Ci%C3%A9negas_pupfishes"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div 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You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="120317202" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/120317202/Progressive_levels_of_trait_divergence_along_a_speciation_transect_in_the_Lake_Victoria_cichlid_fish_Pundamilia">Progressive levels of trait divergence along a ‘speciation transect’ in the Lake Victoria cichlid fish Pundamilia</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="7541539" href="https://independent.academia.edu/oleseehausen">ole seehausen</a></div><p 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seehausen</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Evolutionary Biology, 2009</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Divergent selection and phenotypic plasticity during incipient speciation in Lake Victoria cichlid fish","attachmentId":40311015,"attachmentType":"pdf","work_url":"https://www.academia.edu/18886649/Divergent_selection_and_phenotypic_plasticity_during_incipient_speciation_in_Lake_Victoria_cichlid_fish","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" 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href="https://independent.academia.edu/oleseehausen">ole seehausen</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Evolutionary Biology, 2009</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Phenotypic divergence but not genetic distance predicts assortative mating among species of a cichlid fish radiation","attachmentId":40311026,"attachmentType":"pdf","work_url":"https://www.academia.edu/18886673/Phenotypic_divergence_but_not_genetic_distance_predicts_assortative_mating_among_species_of_a_cichlid_fish_radiation","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" 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href="https://independent.academia.edu/BNgatunga">Benjamin Ngatunga</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Molecular Ecology, 2020</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Newly discovered cichlid fish biodiversity threatened by hybridization with non‐native species","attachmentId":98417838,"attachmentType":"pdf","work_url":"https://www.academia.edu/96550418/Newly_discovered_cichlid_fish_biodiversity_threatened_by_hybridization_with_non_native_species","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/96550418/Newly_discovered_cichlid_fish_biodiversity_threatened_by_hybridization_with_non_native_species"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="5" data-entity-id="14698471" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/14698471/Community_Genetics_Reveal_Elevated_Levels_of_Sympatric_Gene_Flow_among_Morphologically_Similar_but_Not_among_Morphologically_Dissimilar_Species_of_Lake_Victoria_Cichlid_Fish">Community Genetics Reveal Elevated Levels of Sympatric Gene Flow among Morphologically Similar but Not among Morphologically Dissimilar Species of Lake Victoria Cichlid Fish</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33649473" href="https://independent.academia.edu/MartijnEgas">Martijn Egas</a></div><p class="ds-related-work--metadata ds2-5-body-xs">International Journal of Evolutionary Biology, 2011</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Community Genetics Reveal Elevated Levels of Sympatric Gene Flow among Morphologically Similar but Not among Morphologically Dissimilar Species of Lake Victoria Cichlid Fish","attachmentId":43966561,"attachmentType":"pdf","work_url":"https://www.academia.edu/14698471/Community_Genetics_Reveal_Elevated_Levels_of_Sympatric_Gene_Flow_among_Morphologically_Similar_but_Not_among_Morphologically_Dissimilar_Species_of_Lake_Victoria_Cichlid_Fish","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 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href="https://www.academia.edu/43473156/Hybridization_between_an_endangered_freshwater_fish_and_an_introduced_congeneric_species_and_consequent_genetic_introgression">Hybridization between an endangered freshwater fish and an introduced congeneric species and consequent genetic introgression</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="162430180" href="https://hokudai.academia.edu/YohsukeUemura">Yohsuke Uemura</a></div><p class="ds-related-work--metadata ds2-5-body-xs">PLOS ONE, 2019</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Hybridization between an endangered freshwater fish and an introduced congeneric species and consequent genetic 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data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/18886715/Population_genomic_signatures_of_divergent_adaptation_gene_flow_and_hybrid_speciation_in_the_rapid_radiation_of_Lake_Victoria_cichlid_fishes">Population genomic signatures of divergent adaptation, gene flow and hybrid speciation in the rapid radiation of Lake Victoria cichlid fishes</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="7541539" href="https://independent.academia.edu/oleseehausen">ole seehausen</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Molecular Ecology, 2013</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Population genomic signatures of divergent adaptation, gene flow 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