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In human subjects body growth and development is strictly dependent on Zn. The nervous, reproductive and immune systems are particularly influenced by Zn deficiency, as well as by increased levels of Zn. The relationship between Zn and the immune system is complex, since there are four different types of influence associated with Zn. (1) The dietary intake and the resorption of Zn depends on the composition of the diet and also on age and disease status. (2) Zn is a cofactor in more than 300 enzymes influencing various organ functions having a secondary effect on the immune system. (3) Direct effects of Zn on the production, maturation and function of leucocytes. (4) Zn influences the function of immunostimulants used in the experimental systems. Here we summarize all four types of influence on the immune function. Nutritional aspects of Zn, the physiology of Zn, the influence of Zn on enzymes and cellular functions, direct effects of Zn on leucocytes at the cellular and molecular level, Zn-altered function of immunostimulants and the therapeutic use of Zn will be discussed in detail."> <meta name="citation_doi" content="10.1017/S0029665100000781"> <link rel="alternate" href="/core/journals/proceedings-of-the-nutrition-society/article/zinc-and-the-immune-system/23B26245CF0F773E5F1AA19E9800B82B" hreflang="en" /> <link rel="icon" href="/core/cambridge-core/public/images/favicon.ico" type="image/x-icon"/> <link rel="shortcut icon" href="/core/cambridge-core/public/images/favicon.ico" type="image/x-icon"/> <link href='//fonts.googleapis.com/css?family=Noto+Sans:400,700,400italic,700italic' rel='stylesheet' type='text/css'>  <link rel="stylesheet" href="/core/cambridge-core/public/css/app.css?version=v7.337.1-hotfix"/> <link rel="dns-prefetch" href="https://usage.prod.aop.cambridge.org/v1/events"> 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data-v-63dfaf6e>Volume 59 Issue 4</span> </a></li><li class="page-breadcrumbs__item" data-v-3692cf84><span aria-hidden="true" class="breadcrumbs-wrapper__arrow" data-v-3692cf84>></span><span data-v-3692cf84>Zinc and the immune system</span></li></ul></div></div> <div class="language" data-v-3692cf84><ul class="language-switch" data-v-6b1118dd data-v-3692cf84><li aria-label="English" data-v-6b1118dd><span class="language-option current divider" data-v-6b1118dd>English</span></li><li aria-label="Français" data-v-6b1118dd><span role="button" tabindex="0" href="#" lang="fr" class="language-option" data-v-6b1118dd> Français </span></li></ul></div></div></div></div> <div class="container container__modified" data-v-01274b1d>  <div class="row" data-v-01274b1d><div role="complementary" aria-label="table of content" class="column__left" data-v-01274b1d><div class="col journal-container row" data-v-146270e8 data-v-01274b1d><img src="https://static.cambridge.org/covers/PNS_0_0_0/proceedings-of-the-nutrition-society.jpg" alt="" class="journal__image" data-v-146270e8> <a href="/core/journals/proceedings-of-the-nutrition-society" class="app-link journal__title app-link__text app-link--underlined" data-v-63dfaf6e data-v-146270e8><span class="text" data-v-63dfaf6e>Proceedings of the Nutrition Society </span> </a> <hr aria-hidden="true" class="separator default" data-v-7036083a data-v-146270e8></div>  <div id="toc" class="table-of-content" data-v-01274b1d><h2>Article contents</h2> <div id="toc-list-wrapper" class="table-of-content__wrapper"><ul id="toc-list" class="list"><li class="list__item"><a href="#sec0" class="list__item__link"><span class="toc-title">Abstract</span></a></li>  <li class="list__item"><a href="#references-list" class="list__item__link"><span class="toc-title">References</span></a></li></ul></div></div></div> <div class="column__main" data-v-01274b1d><div class="row" data-v-01274b1d><div class="column__main__left" data-v-01274b1d><div id="maincontent" class="col" data-v-862424e6 data-v-01274b1d> <hgroup data-v-862424e6><h1 data-v-862424e6>Zinc and the immune system</h1> </hgroup>     <div class="row published-date" data-v-862424e6><p data-v-862424e6> Published online by Cambridge University Press: <strong data-v-862424e6>28 February 2007</strong></p></div>   <div class="contributors-details" data-v-99f6eb26 data-v-862424e6><div class="row contributors" data-v-99f6eb26><div class="col" data-v-99f6eb26><div class="row contributor-type" data-v-792406ce data-v-99f6eb26> <div class="contributor-type__contributor" data-v-792406ce><a href="/core/search?filters%5BauthorTerms%5D=Lothar%20Rink&eventCode=SE-AU" class="app-link app-link__text app-link--accent" data-v-63dfaf6e data-v-792406ce><span data-v-63dfaf6e>Lothar Rink</span> </a>  <span data-v-792406ce></span></div> </div> </div> <div class="col-2 collapse-link" data-v-99f6eb26><a href="#authors-details" data-toggle="collapse" aria-expanded="false" aria-controls="authors-details" class="app-link collapsed app-link__text-icon app-link--secondary reverse" data-v-63dfaf6e data-v-99f6eb26><img src="data:image/svg+xml;base64,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" alt="" class="app-icon icon arrow-down" data-v-d2c09870 data-v-63dfaf6e><span class="text" data-v-63dfaf6e>Show author details </span> </a></div></div> <hr aria-hidden="true" class="separator default" data-v-7036083a data-v-99f6eb26> <dl id="authors-details" class="authors-details collapse" data-v-2edb8da6 data-v-99f6eb26><div data-test-author="Lothar Rink" class="row author" data-v-2edb8da6><dt class="col-12 col-sm-2 title" data-v-2edb8da6>Lothar Rink*</dt> <dd class="col content d-inline d-sm-flex" data-v-2edb8da6><span class="content__title" data-v-2edb8da6>Affiliation:</span> <div class="d-sm-flex flex-column flex-sm-1 d-inline" data-v-2edb8da6><span data-v-2edb8da6><span data-v-2edb8da6>Institute of Immunology and Transfusion Medicine, University of Lübeck School of Medicine, Ratzeburger Allee 160, D-23538 Lübeck, Germany</span> </span></div></dd></div> <div class="row" data-v-2edb8da6><dt class="col-sm-2 col-12 title" data-v-2edb8da6> * </dt> <dd class="col content" data-v-2edb8da6><div class="row" data-v-2edb8da6><div class="d-sm-flex d-inline flex-sm-1 flex-sm-wrap" data-v-2edb8da6><div class="d-inline" data-v-2edb8da6><span data-v-2edb8da6><div class="corresp"><span class="bold">Corresponding Author:</span> Dr Lothar Rink, fax +49 451 500 3069, email <a href="mailto:rink@immu.mu-luebeck.de">rink@immu.mu-luebeck.de</a></div></span></div></div></div></dd></div> <hr aria-hidden="true" class="separator default" data-v-7036083a data-v-2edb8da6></dl></div></div> <div id="app-tabs" class="tabs" data-v-1d90c6ce data-v-01274b1d><div id="app-tabs-wrapper" class="tabs__wrapper" data-v-1d90c6ce><div role="navigation" aria-label="tab navigation" class="container" data-v-1d90c6ce><a data-toggle="collapse" href="#appTabs" role="button" aria-expanded="false" aria-controls="appTabs" class="tabs__collapse collapsed d-sm-none d-print-none" data-v-1d90c6ce><span data-v-1d90c6ce></span> <span class="tabs-arrow-up" data-v-1d90c6ce></span> <span class="tabs-arrow-down" data-v-1d90c6ce></span></a> <ul id="appTabs" 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target="_blank" href="https://s100.copyright.com/AppDispatchServlet?publisherName=CUP&publication=PNS&title=Zinc%20and%20the%20immune%20system&publicationDate=28%20February%202007&author=Lothar%20Rink©right=Copyright%20%C2%A9%20The%20Nutrition%20Society%202000&contentID=10.1017%2FS0029665100000781&startPage=541&endPage=552&orderBeanReset=True&volumeNum=59&issueNum=4&oa=" data-test-id="buttonRightLink" class="app-link rights-link d-print-none app-link__text-icon app-link--accent" data-v-63dfaf6e data-v-92ee52a2 data-v-43a4d572><img src="/core/page-component/img/rights-icon.d4a677c.svg" alt="" class="app-icon icon rights" data-v-d2c09870 data-v-63dfaf6e><span class="text" data-v-63dfaf6e>Rights & Permissions </span> <span class="sr-only" data-v-63dfaf6e>[Opens in a new window]</span></a></div> <hr aria-hidden="true" class="separator default" data-v-7036083a></div> <div class="share-modal-overlay" style="display:none;" data-v-43a4d572></div> <div data-spy="scroll" data-target="#toc" class="scrollspy-content" data-v-43a4d572> <div id="sec0" class="col article-abstract sec" data-v-2fa8b348 data-v-43a4d572><div class="abstract-text-container" data-v-2fa8b348><div lang="en"><h2>Abstract</h2> <div class="no-content" data-v-6723a3bd> Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button. </div> <div class="abstract-content"><div class="abstract" data-abstract-type="normal"><p>Zn is an essential trace element for all organisms. In human subjects body growth and development is strictly dependent on Zn. The nervous, reproductive and immune systems are particularly influenced by Zn deficiency, as well as by increased levels of Zn. The relationship between Zn and the immune system is complex, since there are four different types of influence associated with Zn. (1) The dietary intake and the resorption of Zn depends on the composition of the diet and also on age and disease status. (2) Zn is a cofactor in more than 300 enzymes influencing various organ functions having a secondary effect on the immune system. (3) Direct effects of Zn on the production, maturation and function of leucocytes. (4) Zn influences the function of immunostimulants used in the experimental systems. Here we summarize all four types of influence on the immune function. Nutritional aspects of Zn, the physiology of Zn, the influence of Zn on enzymes and cellular functions, direct effects of Zn on leucocytes at the cellular and molecular level, Zn-altered function of immunostimulants and the therapeutic use of Zn will be discussed in detail.</p></div></div> <hr aria-hidden="true" class="abstract-divider separator default" data-v-7036083a></div></div>   </div>  <div class="keywords" data-v-86c27100 data-v-43a4d572><h2 data-v-86c27100>Keywords</h2> <div class="row keywords__pills" data-v-86c27100><a href="/core/search?filters[keywords]=Zinc" data-v-f0b31360 data-v-86c27100><span data-v-f0b31360 data-v-86c27100>Zinc</span></a><a href="/core/search?filters[keywords]=Immune system" data-v-f0b31360 data-v-86c27100><span data-v-f0b31360 data-v-86c27100>Immune system</span></a></div> <hr aria-hidden="true" class="separator default" data-v-7036083a data-v-86c27100></div>  <dl class="article-details" data-v-6e32a161 data-v-43a4d572><div class="row" data-v-6e32a161><dt class="col-12 col-sm-3 col-md-2_5 title" data-v-6e32a161> Type </dt> <dd class="col content" data-v-6e32a161>Meeting Report</dd></div> <div class="row" data-v-6e32a161><dt class="col-12 col-sm-3 col-md-2_5 title" data-v-6e32a161> Information </dt> <dd class="col content" data-v-6e32a161><div class="content__journal" data-v-6e32a161><a href="/core/journals/proceedings-of-the-nutrition-society" class="app-link app-link__text app-link--underlined" data-v-63dfaf6e data-v-6e32a161><span class="text" data-v-63dfaf6e>Proceedings of the Nutrition Society </span> </a> <span data-v-6e32a161> , <a href="/core/journals/proceedings-of-the-nutrition-society/volume/6C6AB2C46968797F0F3D28EEB89A8F1A" class="app-link app-link__text app-link--underlined" data-v-63dfaf6e data-v-6e32a161><span class="text" data-v-63dfaf6e>Volume 59 </span> </a></span> <span data-v-6e32a161> , <a href="/core/journals/proceedings-of-the-nutrition-society/issue/291F2C050F6BE5D2C4934A5DEFD062F2" class="app-link app-link__text app-link--underlined" data-v-63dfaf6e data-v-6e32a161><span class="text" data-v-63dfaf6e>Issue 4 </span> </a></span> <span data-v-6e32a161>, November 2000</span>  <span data-v-6e32a161>, pp. 541 - 552</span> </div> <div class="doi-data" data-v-6e32a161><div data-v-6e32a161>DOI: <a target="_blank" href="https://doi.org/10.1017/S0029665100000781" class="app-link app-link__text app-link--accent" data-v-63dfaf6e data-v-6e32a161><span class="text" data-v-63dfaf6e>https://doi.org/10.1017/S0029665100000781 </span> <span class="sr-only" data-v-63dfaf6e>[Opens in a new window]</span></a></div> </div>  </dd></div>   <div class="row" data-v-6e32a161><dt class="col-12 col-sm-3 col-md-2_5 title" data-v-6e32a161> Copyright </dt> <dd class="col content" data-v-6e32a161><div data-v-6e32a161> Copyright © The Nutrition Society 2000 </div></dd></div></dl>  <div id="content-container" class="content-container" data-v-43a4d572>   <hr aria-hidden="true" class="list-divider 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{layout:"default",data:[{article:{id:"23B26245CF0F773E5F1AA19E9800B82B",metadata:{title:K,htmlTitle:K,subtitle:a,authorsGroup:{authors:{contributors:[{givenNames:"Lothar",surname:"Rink",nameStyle:"western",affiliations:[{text:"Institute of Immunology and Transfusion Medicine, University of Lübeck School of Medicine, Ratzeburger Allee 160, D-23538 Lübeck, Germany"}],isCorresponding:e,notes:"\u003Cdiv class=\"corresp\"\u003E\u003Cspan class=\"bold\"\u003ECorresponding Author:\u003C\u002Fspan\u003E Dr Lothar Rink, fax +49 451 500 3069, email \u003Ca href=\"mailto:rink@immu.mu-luebeck.de\"\u003Erink@immu.mu-luebeck.de\u003C\u002Fa\u003E\u003C\u002Fdiv\u003E",isAnonymous:b,fullName:"Lothar Rink",searchUrl:"\u002Fcore\u002Fsearch?filters%5BauthorTerms%5D=Lothar%20Rink&eventCode=SE-AU",orcidUrl:i}]},translators:{contributors:[],label:"Translated by"}},collections:[],publishedDate:"28 February 2007",keywords:[{url:"\u002Fcore\u002Fsearch?filters[keywords]=Zinc",name:"Zinc"},{url:"\u002Fcore\u002Fsearch?filters[keywords]=Immune system",name:"Immune system"}],openPracticeBadges:[],doi:{url:"https:\u002F\u002Fdoi.org\u002F10.1017\u002FS0029665100000781",value:"10.1017\u002FS0029665100000781"},copyright:{statement:["Copyright © The Nutrition Society 2000"],holder:["The Nutrition Society"],year:[2000]},creativeCommons:i,acceptedManuscript:b,type:"meeting-report",pageRange:{range:"541 - 552",firstPage:aO,lastPage:"552"},typeDescription:"Meeting Report",commentsCount:aP,topicsAndSubtopics:i},journal:{id:aQ,title:L,titleSlug:aR,mnemonic:"PNS",titleHistory:[],isFirstView:b,journalSlug:aR,isCompanion:b,parentCompanionJournalName:L,associatedParentCollection:i,paymentInfo:{prices:{"£":{price:26,sku:M,skuNew:G,currency:"£"},"€":{price:31,sku:M,skuNew:G,currency:"€"},US$:{price:36,sku:M,skuNew:G,currency:"US$"},AU$:{price:51,sku:M,skuNew:G,currency:"AU$"}}},url:aS,firstViewUrl:"\u002Fcore\u002Fjournals\u002Fproceedings-of-the-nutrition-society\u002Ffirstview",coverUrl:"https:\u002F\u002Fstatic.cambridge.org\u002Fcovers\u002FPNS_0_0_0\u002Fproceedings-of-the-nutrition-society.jpg",submitMaterialsUrl:"\u002Fcore\u002Fjournals\u002Fproceedings-of-the-nutrition-society\u002Finformation\u002Fauthor-instructions\u002Fsubmitting-your-materials",hasHistory:b,latestTitle:L,latestId:aQ,hasPastTitle:b,issue:{id:"291F2C050F6BE5D2C4934A5DEFD062F2",number:H,title:"Issue 4",publishedDate:"November 2000",printPublishTimestamp:973036800000,url:aT},volume:{id:"6C6AB2C46968797F0F3D28EEB89A8F1A",number:aU,title:"Volume 59",publishedDate:"February 2000",printPublishTimestamp:949363200000,url:"\u002Fcore\u002Fjournals\u002Fproceedings-of-the-nutrition-society\u002Fvolume\u002F6C6AB2C46968797F0F3D28EEB89A8F1A"}},abstract:{textAbstracts:[{title:"Abstract",content:"\u003Cdiv class=\"abstract\" data-abstract-type=\"normal\"\u003E\u003Cp\u003EZn is an essential trace element for all organisms. In human subjects body growth and development is strictly dependent on Zn. The nervous, reproductive and immune systems are particularly influenced by Zn deficiency, as well as by increased levels of Zn. The relationship between Zn and the immune system is complex, since there are four different types of influence associated with Zn. (1) The dietary intake and the resorption of Zn depends on the composition of the diet and also on age and disease status. (2) Zn is a cofactor in more than 300 enzymes influencing various organ functions having a secondary effect on the immune system. (3) Direct effects of Zn on the production, maturation and function of leucocytes. (4) Zn influences the function of immunostimulants used in the experimental systems. Here we summarize all four types of influence on the immune function. Nutritional aspects of Zn, the physiology of Zn, the influence of Zn on enzymes and cellular functions, direct effects of Zn on leucocytes at the cellular and molecular level, Zn-altered function of immunostimulants and the therapeutic use of Zn will be discussed in detail.\u003C\u002Fp\u003E\u003C\u002Fdiv\u003E",lang:aV}]},content:{html:"\u003Cdiv\u003E\u003C\u002Fdiv\u003E",tableOfContent:[],footnotes:[],fulltextNotes:[],references:[{id:"manual_ref-1",displayNumber:a,existInContent:b,content:"\u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EaCampo\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EC\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EWellinghausen\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EN\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EFaber\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EC\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EFischer\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERink\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E2000\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EZinc inhibits the mixed lymphocyte culture\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EBiological Trace Element Research\u003C\u002Fspan\u003E (In the Press).\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for Zinc inhibits the mixed lymphocyte culture' href=https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Zinc+inhibits+the+mixed+lymphocyte+culture&author=aCampo+C&author=Wellinghausen+N&author=Faber+C&author=Fischer+A&author=Rink+L&publication+year=2000&journal=Biological+Trace+Element+Research\u003EGoogle Scholar\u003C\u002Fa\u003E",item:[{googleScholarLink:"https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Zinc+inhibits+the+mixed+lymphocyte+culture&author=aCampo+C&author=Wellinghausen+N&author=Faber+C&author=Fischer+A&author=Rink+L&publication+year=2000&journal=Biological+Trace+Element+Research",openUrlParams:{genre:d,atitle:aW,jtitle:s,title:s,volume:i,artnum:"65dfa79b2124760001ca5b1f",spage:i,epage:i,date:N,sid:c,aulast:a,aufirst:a,doi:a,au:a},innerRefId:"ref001",title:aW,doi:a,crossRefLink:a,pubMedLink:a}]},{id:"manual_ref-2",displayNumber:a,existInContent:b,content:"\u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EAicher\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EWK\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EHeer\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EAH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ETrabandt\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBridges\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ESL\u003C\u002Fspan\u003E \u003Cspan class=\"suffix\"\u003EJr\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ESchroeder\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EHW\u003C\u002Fspan\u003E \u003Cspan class=\"suffix\"\u003EJr\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EStransky\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EG\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGay\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ERE\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EEibel\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EPeter\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EHH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ESiebenlist\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EU\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EKoopman\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EWJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGay\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ES\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1994\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EOverexpression of zinc-finger transcription factor z-225\u002FEgr-1 in synoviocytes from rheumatoid arthritis patients\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EJournal of Immunology\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E152\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E5940\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E5948\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='CrossRef link for Overexpression of zinc-finger transcription factor z-225\u002FEgr-1 in synoviocytes from rheumatoid arthritis patients' href=https:\u002F\u002Fdx.doi.org\u002F10.4049\u002Fjimmunol.152.12.5940\u003ECrossRef\u003C\u002Fa\u003E\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for Overexpression of zinc-finger transcription factor z-225\u002FEgr-1 in synoviocytes from rheumatoid arthritis patients' href=https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Overexpression+of+zinc-finger+transcription+factor+z-225%2FEgr-1+in+synoviocytes+from+rheumatoid+arthritis+patients&author=Aicher+WK&author=Heer+AH&author=Trabandt+A&author=Bridges+SL&author=Schroeder+HW&author=Stransky+G&author=Gay+RE&author=Eibel+H&author=Peter+HH&author=Siebenlist+U&author=Koopman+WJ&author=Gay+S&publication+year=1994&journal=Journal+of+Immunology&volume=152&doi=10.4049%2Fjimmunol.152.12.5940&pages=5940-5948\u003EGoogle Scholar\u003C\u002Fa\u003E\u003Ca class='ref-link' target='_blank' aria-label='PubMed link for Overexpression of zinc-finger transcription factor z-225\u002FEgr-1 in synoviocytes from rheumatoid arthritis patients' href=https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F8207219\u003EPubMed\u003C\u002Fa\u003E",item:[{googleScholarLink:"https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Overexpression+of+zinc-finger+transcription+factor+z-225%2FEgr-1+in+synoviocytes+from+rheumatoid+arthritis+patients&author=Aicher+WK&author=Heer+AH&author=Trabandt+A&author=Bridges+SL&author=Schroeder+HW&author=Stransky+G&author=Gay+RE&author=Eibel+H&author=Peter+HH&author=Siebenlist+U&author=Koopman+WJ&author=Gay+S&publication+year=1994&journal=Journal+of+Immunology&volume=152&doi=10.4049%2Fjimmunol.152.12.5940&pages=5940-5948",openUrlParams:{genre:d,atitle:aX,jtitle:t,title:t,volume:al,artnum:"65dfa79b2124760001ca5b20",spage:"5940",epage:"5948",date:w,sid:c,aulast:a,aufirst:a,doi:aY,au:a},innerRefId:"ref002",title:aX,pubMedId:"8207219",doi:aY,crossRefLink:"https:\u002F\u002Fdx.doi.org\u002F10.4049\u002Fjimmunol.152.12.5940",pubMedLink:"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F8207219"}]},{id:"manual_ref-3",displayNumber:a,existInContent:b,content:"\u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EAicher\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EWK\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ESakamoto\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EKM\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EHack\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EEibel\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1999\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EAnalysis of functional elements in the human Egr-1 gene promoter\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003ERheumatology International\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E8\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E207\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E214\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='CrossRef link for Analysis of functional elements in the human Egr-1 gene promoter' href=https:\u002F\u002Fdx.doi.org\u002F10.1007\u002Fs002960050086\u003ECrossRef\u003C\u002Fa\u003E\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for Analysis of functional elements in the human Egr-1 gene promoter' href=https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Analysis+of+functional+elements+in+the+human+Egr-1+gene+promoter&author=Aicher+WK&author=Sakamoto+KM&author=Hack+A&author=Eibel+H&publication+year=1999&journal=Rheumatology+International&volume=8&doi=10.1007%2Fs002960050086&pages=207-214\u003EGoogle Scholar\u003C\u002Fa\u003E",item:[{googleScholarLink:"https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Analysis+of+functional+elements+in+the+human+Egr-1+gene+promoter&author=Aicher+WK&author=Sakamoto+KM&author=Hack+A&author=Eibel+H&publication+year=1999&journal=Rheumatology+International&volume=8&doi=10.1007%2Fs002960050086&pages=207-214",openUrlParams:{genre:d,atitle:aZ,jtitle:a_,title:a_,volume:am,artnum:"65dfa79b2124760001ca5b21",spage:a$,epage:"214",date:h,sid:c,aulast:a,aufirst:a,doi:ba,au:a},innerRefId:"ref003",title:aZ,doi:ba,crossRefLink:"https:\u002F\u002Fdx.doi.org\u002F10.1007\u002Fs002960050086",pubMedLink:a}]},{id:"manual_ref-4",displayNumber:a,existInContent:b,content:"\u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EAllen\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EJI\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EPerri\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ERT\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EMcClain\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ECJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EKay\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ENE\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1983\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EAlterations in human natural killer cell activity and monocyte cytotoxicity induced by zinc deficiency\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EJournal of Laboratory and Clinical Medicine\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E102\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E577\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E589\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for Alterations in human natural killer cell activity and monocyte cytotoxicity induced by zinc deficiency' href=https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Alterations+in+human+natural+killer+cell+activity+and+monocyte+cytotoxicity+induced+by+zinc+deficiency&author=Allen+JI&author=Perri+RT&author=McClain+CJ&author=Kay+NE&publication+year=1983&journal=Journal+of+Laboratory+and+Clinical+Medicine&volume=102&pages=577-589\u003EGoogle Scholar\u003C\u002Fa\u003E\u003Ca class='ref-link' target='_blank' aria-label='PubMed link for Alterations in human natural killer cell activity and monocyte cytotoxicity induced by zinc deficiency' href=https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F6604771\u003EPubMed\u003C\u002Fa\u003E",item:[{googleScholarLink:"https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Alterations+in+human+natural+killer+cell+activity+and+monocyte+cytotoxicity+induced+by+zinc+deficiency&author=Allen+JI&author=Perri+RT&author=McClain+CJ&author=Kay+NE&publication+year=1983&journal=Journal+of+Laboratory+and+Clinical+Medicine&volume=102&pages=577-589",openUrlParams:{genre:d,atitle:bb,jtitle:z,title:z,volume:an,artnum:"65dfa79b2124760001ca5b22",spage:"577",epage:"589",date:ao,sid:c,aulast:a,aufirst:a,doi:a,au:a},innerRefId:"ref004",title:bb,pubMedId:"6604771",doi:a,crossRefLink:a,pubMedLink:"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F6604771"}]},{id:"manual_ref-5",displayNumber:a,existInContent:b,content:"\u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EAndres\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EME\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBurger\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EC\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EPeral-Rubio\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EMJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBattaglioli\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EE\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EAnderson\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EME\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGrimes\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EDallman\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBallas\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EN\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EMandel\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EG\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1999\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003ECoREST: a functional corepressor required for regulation of neural-specific gene expression\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EProceedings of the National Academy of Sciences USA\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E96\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E9873\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E9878\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='CrossRef link for CoREST: a functional corepressor required for regulation of neural-specific gene expression' href=https:\u002F\u002Fdx.doi.org\u002F10.1073\u002Fpnas.96.17.9873\u003ECrossRef\u003C\u002Fa\u003E\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for CoREST: a functional corepressor required for regulation of neural-specific gene expression' href=https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=CoREST%3A+a+functional+corepressor+required+for+regulation+of+neural-specific+gene+expression&author=Andres+ME&author=Burger+C&author=Peral-Rubio+MJ&author=Battaglioli+E&author=Anderson+ME&author=Grimes+J&author=Dallman+J&author=Ballas+N&author=Mandel+G&publication+year=1999&journal=Proceedings+of+the+National+Academy+of+Sciences+USA&volume=96&doi=10.1073%2Fpnas.96.17.9873&pages=9873-9878\u003EGoogle Scholar\u003C\u002Fa\u003E\u003Ca class='ref-link' target='_blank' aria-label='PubMed link for CoREST: a functional corepressor required for regulation of neural-specific gene expression' href=https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F10449787\u003EPubMed\u003C\u002Fa\u003E",item:[{googleScholarLink:"https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=CoREST%3A+a+functional+corepressor+required+for+regulation+of+neural-specific+gene+expression&author=Andres+ME&author=Burger+C&author=Peral-Rubio+MJ&author=Battaglioli+E&author=Anderson+ME&author=Grimes+J&author=Dallman+J&author=Ballas+N&author=Mandel+G&publication+year=1999&journal=Proceedings+of+the+National+Academy+of+Sciences+USA&volume=96&doi=10.1073%2Fpnas.96.17.9873&pages=9873-9878",openUrlParams:{genre:d,atitle:bc,jtitle:m,title:m,volume:bd,artnum:"65dfa79b2124760001ca5b23",spage:"9873",epage:"9878",date:h,sid:c,aulast:a,aufirst:a,doi:be,au:a},innerRefId:"ref005",title:bc,pubMedId:"10449787",doi:be,crossRefLink:"https:\u002F\u002Fdx.doi.org\u002F10.1073\u002Fpnas.96.17.9873",pubMedLink:"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F10449787"}]},{id:"manual_ref-6",displayNumber:a,existInContent:b,content:"\u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EAntonucci\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EDi-Baldassarre\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EDi-Giacomo\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EF\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EStuppia\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EPalka\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EG\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1997\u003C\u002Fspan\u003E) \u003Cspan 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class=\"given-names\"\u003EN\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGoldkorn\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ET\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ENhan\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ERT\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EDang\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ELB\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EScott\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ES\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERidgley\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ERM\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERasooly\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EWright\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ESC\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ELarrick\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EJW\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERasooly\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ER\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ECarlson\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EJR\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1998\u003C\u002Fspan\u003E) \u003Cspan 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XIII: Therapy with zinc in presymptomatic patients from the time of diagnosis\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EJournal of Laboratory and Clinical Medicine\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E123\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E849\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E858\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for Treatment of Wilson's disease with zinc. 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class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ECakman\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EI\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERohwer\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ESchütz\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ERM\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EKirchner\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERink\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1996\u003C\u002Fspan\u003E) \u003Cspan 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class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ECrea\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGuérin\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EV\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EOrtega\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EF\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EHartemann\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EP\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1990\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EZinc et système immunitaire (Zinc and immune system)\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EAnnales de Medecine Interne\u003C\u002Fspan\u003E \u003Cspan 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class=\"surname\"\u003ECunningham-Rundles\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ES\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBockman\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ERS\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ELin\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGiardina\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EPV\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EHilgartner\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EMW\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ECaldwell-Brown\u003C\u002Fspan\u003E, \u003Cspan 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class=\"given-names\"\u003EE\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EPisaneschi\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EG\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ECamacho-Vanegas\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EO\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBeccari\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EE\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1998\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EThe binding sites for \u003Cem class=\"italic\"\u003EXenopus laevis\u003C\u002Fem\u003E FIII\u002FYY1 in the first exon of L1 and L14 ribosomal protein genes are dispensable for promoter expression\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EEuropean Journal 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class=\"given-names\"\u003EC\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EHirv\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EK\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EKirchner\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERink\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1995\u003C\u002Fspan\u003E \u003Cem class=\"italic\"\u003Ea\u003C\u002Fem\u003E) \u003Cspan class=\"article-title\"\u003EDivergent effects of zinc on different bacterial pathogenic agents\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EJournal of Infectious Diseases\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E171\u003C\u002Fspan\u003E, 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class=\"given-names\"\u003EC\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EHirv\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EK\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EKirchner\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERink\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1995\u003C\u002Fspan\u003E \u003Cem class=\"italic\"\u003Eb\u003C\u002Fem\u003E) \u003Cspan class=\"article-title\"\u003EZinc regulates cytokine induction by superantigens and lipopolysaccharide\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EImmunology\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E84\u003C\u002Fspan\u003E, \u003Cspan 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class=\"surname\"\u003EHirv\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EK\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERink\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EKirchner\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1994\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EInduction of cytokines by zinc ions in human peripheral blood mononuclear cells and separated monocytes\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003ELymphokine and Cytokine Research\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E13\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E15\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E20\u003C\u002Fspan\u003E.\u003Ca 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class=\"given-names\"\u003EB\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBurnstine\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EMA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EMartonyi\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ECL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ESugar\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EJohnson\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EV\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBrewer\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EGJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan 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class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EFavier\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EM\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1990\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EConsequences des deficits en zinc durant la grossesse pour la mère et le nouveau-né (Consequences of zinc deficits during pregnancy for the mother and newborn)\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003ERevue Française de Gynecologie et d'Obstetrique\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E85\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E13\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E27\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for Consequences des deficits en zinc durant la grossesse pour la mère et le nouveau-né (Consequences of zinc deficits during pregnancy for the mother and newborn)' 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Scholar\u003C\u002Fa\u003E",item:[{googleScholarLink:"https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Zinc+stimulates+DNA+synthesis+during+its+antiapoptotic+action+independently+with+increments+of+an+antiapoptotic+protein%2C+Bcl-2%2C+in+porcine+kidney+LLC-PK+cells&author=Ishido+M&author=Suzuki+T&author=Adachi+T&author=Kunimoto+M&publication+year=1999&journal=Journal+of+Pharmacology+and+Experimental+Therapeutics&volume=290&pages=923-928",openUrlParams:{genre:d,atitle:es,jtitle:et,title:et,volume:"290",artnum:"65dfa79c2124760001ca5b64",spage:"923",epage:"928",date:h,sid:c,aulast:a,aufirst:a,doi:a,au:a},innerRefId:"ref070",title:es,doi:a,crossRefLink:a,pubMedLink:a}]},{id:"manual_ref-71",displayNumber:a,existInContent:b,content:"\u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EJames\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EK\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1990\u003C\u002Fspan\u003E) \u003Cspan 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class=\"given-names\"\u003EE\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EQui\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EX\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EMust\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ELM\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EHolmes\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ERK\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EHol\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EWG\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1997\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EComparison of high-resolution structures of the diphteria toxin repressor in complex with cobalt and zinc at 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class=\"surname\"\u003EPrasad\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EAS\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBeck\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EFW\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EKaplan\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EChandrasekar\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EPH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EOrtega\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EFitzgerald\u003C\u002Fspan\u003E, \u003Cspan 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href=https:\u002F\u002Fdx.doi.org\u002F10.1002\u002F(SICI)1096-8652(199907)61:3\u003C194::AID-AJH6\u003E3.0.CO;2-C\u003ECrossRef\u003C\u002Fa\u003E\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for Effect of zinc supplementation on incidence of infections and hospital admission in sickle cell disease (SCD)' href=https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Effect+of+zinc+supplementation+on+incidence+of+infections+and+hospital+admission+in+sickle+cell+disease+(SCD)&author=Prasad+AS&author=Beck+FW&author=Kaplan+J&author=Chandrasekar+PH&author=Ortega+J&author=Fitzgerald+JT&author=Swerdlow+P&publication+year=1999&journal=American+Journal+of+Hematology&volume=61&doi=10.1002%2F(SICI)1096-8652(199907)61%3A3%3C194%3A%3AAID-AJH6%3E3.0.CO%3B2-C&pages=194-202\u003EGoogle Scholar\u003C\u002Fa\u003E\u003Ca class='ref-link' target='_blank' aria-label='PubMed link for Effect of zinc supplementation on incidence of infections and hospital admission in sickle 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href=https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F10398312\u003EPubMed\u003C\u002Fa\u003E",item:[{googleScholarLink:"https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Effect+of+zinc+supplementation+on+incidence+of+infections+and+hospital+admission+in+sickle+cell+disease+(SCD)&author=Prasad+AS&author=Beck+FW&author=Kaplan+J&author=Chandrasekar+PH&author=Ortega+J&author=Fitzgerald+JT&author=Swerdlow+P&publication+year=1999&journal=American+Journal+of+Hematology&volume=61&doi=10.1002%2F(SICI)1096-8652(199907)61%3A3%3C194%3A%3AAID-AJH6%3E3.0.CO%3B2-C&pages=194-202",openUrlParams:{genre:d,atitle:gp,jtitle:A,title:A,volume:Q,artnum:"65dfa79c2124760001ca5b8f",spage:aw,epage:"202",date:h,sid:c,aulast:a,aufirst:a,doi:gq,au:a},innerRefId:"ref113",title:gp,pubMedId:"10398312",doi:gq,crossRefLink:"https:\u002F\u002Fdx.doi.org\u002F10.1002\u002F(SICI)1096-8652(199907)61:3\u003C194::AID-AJH6\u003E3.0.CO;2-C",pubMedLink:"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F10398312"}]},{id:"manual_ref-114",displayNumber:a,existInContent:b,content:"\u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EPrasad\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EAS\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EMiaie\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E \u003Cspan class=\"suffix\"\u003EJr\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EFarid\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EZ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ESchulert\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ESandstead\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EHH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1963\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EZinc metabolism in patients with the syndrome of iron deficiency, hypogonadism and dwarfism\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EJournal of Laboratory and Clinical Medicine\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E83\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E537\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E549\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for Zinc metabolism in patients with the syndrome of iron deficiency, hypogonadism and dwarfism' href=https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Zinc+metabolism+in+patients+with+the+syndrome+of+iron+deficiency%2C+hypogonadism+and+dwarfism&author=Prasad+AS&author=Miaie+A&author=Farid+Z&author=Schulert+A&author=Sandstead+HH&publication+year=1963&journal=Journal+of+Laboratory+and+Clinical+Medicine&volume=83&pages=537-549\u003EGoogle Scholar\u003C\u002Fa\u003E",item:[{googleScholarLink:"https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=Zinc+metabolism+in+patients+with+the+syndrome+of+iron+deficiency%2C+hypogonadism+and+dwarfism&author=Prasad+AS&author=Miaie+A&author=Farid+Z&author=Schulert+A&author=Sandstead+HH&publication+year=1963&journal=Journal+of+Laboratory+and+Clinical+Medicine&volume=83&pages=537-549",openUrlParams:{genre:d,atitle:gr,jtitle:z,title:z,volume:"83",artnum:"65dfa79c2124760001ca5b90",spage:"537",epage:"549",date:"1963",sid:c,aulast:a,aufirst:a,doi:a,au:a},innerRefId:"ref114",title:gr,doi:a,crossRefLink:a,pubMedLink:a}]},{id:"manual_ref-115",displayNumber:a,existInContent:b,content:"\u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EProvinciali\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EM\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EMontenovo\u003C\u002Fspan\u003E, \u003Cspan 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class=\"given-names\"\u003EP\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EWillems\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EWR\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBreidenbach\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ET\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGuttmann\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EW\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EPabst\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EW\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ESchutterle\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EG\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan 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class=\"given-names\"\u003EH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EKirchner\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1978\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EMonocyte-dependent stimulation of human T cells by zinc\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EClinical and Experimental Immunology\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E32\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E484\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E488\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for Monocyte-dependent stimulation of human T cells by zinc' 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class=\"given-names\"\u003EB\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EKovar\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EIZ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERauscher\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EFairweather-Tait\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ES\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EBeattie\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EMcArdle\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EHJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EAhmed\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ER\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGreen\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EC\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1997\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EA case of hyperzincemia with functional zinc depletion: a new disorder?\u003C\u002Fspan\u003E \u003Cspan class=\"source\"\u003EPediatric Research\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E42\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E219\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E225\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='CrossRef link for A case of hyperzincemia with functional zinc depletion: a new disorder?' 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href=https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F9262226\u003EPubMed\u003C\u002Fa\u003E",item:[{googleScholarLink:"https:\u002F\u002Fscholar.google.com\u002Fscholar_lookup?title=A+case+of+hyperzincemia+with+functional+zinc+depletion%3A+a+new+disorder%3F&author=Sampson+B&author=Kovar+IZ&author=Rauscher+A&author=Fairweather-Tait+S&author=Beattie+J&author=McArdle+HJ&author=Ahmed+R&author=Green+C&publication+year=1997&journal=Pediatric+Research&volume=42&doi=10.1203%2F00006450-199708000-00015&pages=219-225",openUrlParams:{genre:d,atitle:gW,jtitle:gX,title:gX,volume:aA,artnum:"65dfa79c2124760001ca5b9d",spage:"219",epage:bl,date:o,sid:c,aulast:a,aufirst:a,doi:gY,au:a},innerRefId:"ref127",title:gW,pubMedId:"9262226",doi:gY,crossRefLink:"https:\u002F\u002Fdx.doi.org\u002F10.1203\u002F00006450-199708000-00015",pubMedLink:"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpubmed\u002F9262226"}]},{id:"manual_ref-128",displayNumber:a,existInContent:b,content:"\u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ESandstead\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EHH\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EHenriksen\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ELK\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGreger\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EJL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EPrasad\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EAS\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGood\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ERA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1982\u003C\u002Fspan\u003E) \u003Cspan 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class=\"given-names\"\u003EPA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1976\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EOral zinc sulphate in rheumatoid arthritis\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003ELancet\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003Eii\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E539\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E542\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='CrossRef link for Oral zinc sulphate in rheumatoid arthritis' href=https:\u002F\u002Fdx.doi.org\u002F10.1016\u002FS0140-6736(76)91793-1\u003ECrossRef\u003C\u002Fa\u003E\u003Ca class='ref-link' target='_blank' aria-label='Google Scholar link for Oral zinc sulphate in rheumatoid arthritis' 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class=\"given-names\"\u003EN\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EDriessen\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EC\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERink\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1996\u003C\u002Fspan\u003E \u003Cem class=\"italic\"\u003Ea\u003C\u002Fem\u003E) \u003Cspan class=\"article-title\"\u003EStimulation of human peripheral blood mononuclear cells by zinc and related cations\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003ECytokine\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E18\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E767\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E771\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='CrossRef link 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class=\"given-names\"\u003EN\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EMartin\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EM\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERink\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1997\u003C\u002Fspan\u003E \u003Cem class=\"italic\"\u003Eb\u003C\u002Fem\u003E) \u003Cspan class=\"article-title\"\u003EZinc inhibits IL-1 dependent T cell stimulation\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EEuropean Journal of Immunology\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E27\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E2529\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E2535\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='CrossRef link for Zinc 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class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERink\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1996\u003C\u002Fspan\u003E \u003Cem class=\"italic\"\u003Ec\u003C\u002Fem\u003E) \u003Cspan class=\"article-title\"\u003EZinc enhances lipopolysaccharide-induced monokine secretion by a fluidity change of lipopolysaccharide\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EJournal of Immunology\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E157\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E3139\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E3145\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='CrossRef link for Zinc enhances lipopolysaccharide-induced monokine secretion by a fluidity change of lipopolysaccharide' href=https:\u002F\u002Fdx.doi.org\u002F10.4049\u002Fjimmunol.157.7.3139\u003ECrossRef\u003C\u002Fa\u003E\u003Ca 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class=\"given-names\"\u003EAJ\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EKhachigian\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ELM\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EShows\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ET\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ECollins\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ET\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1995\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003EIsolation and characterization of a novel zinc-finger protein with transcription repressor activity\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EJournal of Biological Chemistry\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E270\u003C\u002Fspan\u003E, \u003Cspan 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class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ESerfass\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ERE\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ENelson\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ESE\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EFigueroa-Colon\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ER\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EEdwards\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EBB\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EHouk\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ERS\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EThompson\u003C\u002Fspan\u003E, 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class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EZoli\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EAltomonte\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ECaricchio\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003ER\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EGaossi\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EA\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EMirone\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EL\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E, \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003ERuffini\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EMP\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E & \u003Cspan class=\"name\"\u003E\u003Cspan class=\"surname\"\u003EMagaro\u003C\u002Fspan\u003E, \u003Cspan class=\"given-names\"\u003EM\u003C\u002Fspan\u003E\u003C\u002Fspan\u003E (\u003Cspan class=\"year\"\u003E1998\u003C\u002Fspan\u003E) \u003Cspan class=\"article-title\"\u003ESerum zinc and copper in active rheumatoid arthritis: correlation with interleukin 1 beta and tumour necrosis factor alpha\u003C\u002Fspan\u003E. \u003Cspan class=\"source\"\u003EClinical Rheumatology\u003C\u002Fspan\u003E \u003Cspan class=\"volume\"\u003E17\u003C\u002Fspan\u003E, \u003Cspan class=\"fpage\"\u003E378\u003C\u002Fspan\u003E–\u003Cspan class=\"lpage\"\u003E382\u003C\u002Fspan\u003E.\u003Ca class='ref-link' target='_blank' aria-label='CrossRef link for Serum zinc and copper in active rheumatoid arthritis: correlation with interleukin 1 beta and tumour necrosis factor alpha' 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Today","Proceedings of the National Academy of Sciences USA","1993","1997","17","International Journal of Immunopharmacology","1992","Biological Trace Element Research","Journal of Immunology","Science","EMBO Journal","1994","1989","93","Journal of Laboratory and Clinical Medicine","American Journal of Hematology","1990","Biochemical and Biophysical Research Communications","15","American Journal of Clinical Nutrition","Cellular Immunology","S0029665100000781","4","10","11","Zinc and the immune system","Proceedings of the Nutrition Society","article_pns_ind_pur","2000","Ultrastructural Pathology","14","61","Infection and Immunity","Journal of Nutrition","book","Mechanisms of Ageing and Development","89","Journal of Biological Chemistry","Annals of the New York Academy of Sciences","European Journal of Biochemistry","Journal of Infectious Diseases","Immunology","20","26","27","International Journal of Cancer","Journal of the American College of Nutrition","American Journal of Physiology","73","Proceedings of the Society for Experimental Biology and Medicine","1","Annals of Internal Medicine","Clinical and Experimental Immunology","Lancet","152","8","102","1983","21","1981","3","280","50","45","55","194","Clinical, Biochemical, and Nutritional Aspects of Trace Elements","139","1984","42","16","113","1986","171","85","Glutathione in the Nervous System","Zinc in Human Biology. Human Nutrition Reviews","261","94","103","31","137","Programmed Cell Death: The Cellular and Molecular Biology of Apoptosis","541",0,"FC2E14A339DC9AC62F0C935F1B109083","proceedings-of-the-nutrition-society","\u002Fcore\u002Fjournals\u002Fproceedings-of-the-nutrition-society","\u002Fcore\u002Fjournals\u002Fproceedings-of-the-nutrition-society\u002Fissue\u002F291F2C050F6BE5D2C4934A5DEFD062F2","59","en","Zinc inhibits the mixed lymphocyte culture","Overexpression of zinc-finger transcription factor z-225\u002FEgr-1 in synoviocytes from rheumatoid arthritis patients","10.4049\u002Fjimmunol.152.12.5940","Analysis of functional elements in the human Egr-1 gene promoter","Rheumatology International","207","10.1007\u002Fs002960050086","Alterations in human natural killer cell activity and monocyte cytotoxicity induced by zinc deficiency","CoREST: a functional corepressor required for regulation of neural-specific gene expression","96","10.1073\u002Fpnas.96.17.9873","Detection of apoptosis in peripheral blood cells of 31 subjects affected by Down syndrome before and after zinc therapy","10.3109\u002F01913129709021944","Expression of myelin transcription factor I (MyTI), a 'zinc-finger' DNA-binding protein, in developing oligodendrocytes","Glia","10.1002\u002Fglia.440140407","The multi-faceted zinc dependency of the immune system","225","10.1016\u002F0167-5699(81)90052-9","Thymulin (FTS-Zn)","Clinics in Immunology and Allergy","150","10.1016\u002FS0260-4639(22)00263-8","Autoinducer of virulence as a target for vaccine and therapy against Staphylococcus aureus","10.1126\u002Fscience.280.5362.438","Autocrine regulation of toxin synthesis by Staphylococcus aureus","92","10.1073\u002Fpnas.92.5.1619","Zinc, copper and selenium in reproduction","Experientia","10.1007\u002FBF01952862","Influx of zinc by channel catfish (Ictalurus punctatus): uptake from external environmental solutions","Comparative Biochemistry and Physiology","217","Characterization of lymphocyte transformation induced by zinc ions","Journal of Cellular Biology","1974","10.1083\u002Fjcb.61.1.45","Functional analysis of Mycoplasma arthritidis-derived mitogen interaction with class II molecules","10.1128\u002Fiai.65.6.2000-2005.1997","Physiological roles of zinc in the plasma membrane of mammalian cells","Journal of Nutritional Biochemistry","10.1016\u002F0955-2863(93)90052-X","Effects of zinc supplementation in chronic haemodialysis patients","Nephrology Dialysis and Transplantation","Parenteral zinc supplementation in adult humans during the acute phase response increases the febrile response","10.1093\u002Fjn\u002F127.1.70","Zinc inhibition of calmodulin: a proposed molecular mechanism of zinc action on cellular functions","7","60","1979","10.1002\u002Fajh.2830070107","1982","Treatment of Wilson's disease with zinc. XIII: Therapy with zinc in presymptomatic patients from the time of diagnosis","Wilson disease","Medicine","71","164","10.1097\u002F00005792-199205000-00004","Zinc supplementation restores plasma concentrations of zinc and thymulin in patients with Crohn's disease","Alimentary and Pharmacology and Therapeutics","10.1111\u002Fj.1365-2036.1993.tb00098.x","Zinc supplementation and hepatitis B vaccination in chronic haemodialysis patients a multicentre study","Nephrology Dialysis Transplantation","Zinc modulates the mitogenic activation of human peripheral blood lymphocytes","Annali dell Istituto Superiore di Sanita","Zinc supplementation reconstitutes the production of interferon-α by leukocytes from elderly persons","Journal of Interferon and Cytokine Research","10.1089\u002Fjir.1997.17.469","Dysregulation between TH1 and TH2 T cell subpopulations in the elderly","87","10.1016\u002F0047-6374(96)01708-3","A zinc-finger transcription factor induced by TGF-beta promotes apoptotic cell death in epithelial Mv1Lu cells","FEBS Letters","457","10.1016\u002FS0014-5793(99)01051-0","Excessive intake of zinc impairs immune responses","Journal of the American Medical Association","10.1001\u002Fjama.1984.03350110043027","BCL-6, a POZ\u002Fzinc-finger protein, is a sequence-specific transcriptional repressor","10.1073\u002Fpnas.93.14.6947","Molecular mechanisms of zinc-dependent leukocyte adhesion involving the urokinase receptor and β2-integrins","Blood","10.1182\u002Fblood.V93.9.2976.409k21_2976_2983","Trace elements–gene interactions","Nutrition Reviews","223","10.1111\u002Fj.1753-4887.1992.tb01331.x","Effect of zinc on cells and biomembranes","Medical Clinics of North America","1976","10.1016\u002FS0025-7125(16)31862-4","Calprotectin-mediated zinc chelation as a biostatic mechanism in host defense","Scandinavian Journal of Immunology","10.1111\u002Fj.1365-3083.1995.tb03695.x","Zinc proteins: Enzymes, storage proteins, transcription factors and replication proteins","Annual Review of Biochemistry","10.1146\u002Fannurev.bi.61.070192.004341","Structure and mechanism of alkaline phosphatase","Annual Review of Biophysics and Biomolecular Structure","10.1146\u002Fannurev.bb.21.060192.002301","Interleukin 1 regulates secretion of zinc-thymulin by human thymic epithelial cells and its action on T-lymphocyte proliferation and nuclear protein kinase C","10.1073\u002Fpnas.89.16.7752","Zinc et système immunitaire (Zinc and immune system)","Annales de Medecine Interne","Zinc can increase the activity of protein kinase C and contributes to its binding to plasma membrane in T lymphocytes","10.1016\u002FS0021-9258(18)68668-5","Physiological and pharmacological effects of zinc on immune response","122","10.1111\u002Fj.1749-6632.1990.tb00139.x","The binding sites for Xenopus laevis FIII\u002FYY1 in the first exon of L1 and L14 ribosomal protein genes are dispensable for promoter expression","255","10.1046\u002Fj.1432-1327.1998.2550563.x","Wilms tumor gene product WT1 arrests macrophage differentiation of HL-60 cells through its zinc-finger domain","192","10.1006\u002Fbbrc.1998.9896","T-lymphocyte subsets and interleukin-2 production in zinc-deficient rats","British Journal of Nutrition","10.1079\u002FBJN19860010","Divergent effects of zinc on different bacterial pathogenic agents","10.1093\u002Finfdis\u002F171.2.486","Zinc regulates cytokine induction by superantigens and lipopolysaccharide","Induction of cytokines by zinc ions in human peripheral blood mononuclear cells and separated monocytes","Lymphokine and Cytokine Research","13","Influence of serum on zinc, toxic shock syndrome toxin-1, and lipopolysaccharide-induced production of IFN-γ and IL-1β by human mononuclear cells","Journal of Leukocyte Biology","10.1002\u002Fjlb.57.6.904","Influence of oral zinc supplementation on the lymphocyte response to mitogens of normal subjects","88","10.1093\u002Fajcn\u002F34.1.88","Effect of pancreatic enzymes on zinc absorption in cystic fibrosis","Journal of Pediatric Gastroenterology and Nutrition","136","Regression of Kayser-Fleischer rings during oral zinc therapy: correlation with systemic manifestation of WD","Cornea","10.1097\u002F00003226-199611000-00008","Consequences des deficits en zinc durant la grossesse pour la mère et le nouveau-né (Consequences of zinc deficits during pregnancy for the mother and newborn)","Revue Française de Gynecologie et d'Obstetrique","The role of zinc in reproduction. Hormonal mechanisms","32","363","382","10.1007\u002FBF02784623","The human zinc-finger protein-7 gene is located 90 kb 3\u003E of MYC and is not expressed in Burkitt lymphoma cell lines","Zn2+ inhibits both tumor necrosis factor-mediated DNA fragmentation and cytolysis","10.1002\u002Fijc.2910440221","Interrelationships between zinc and immune functions","Federation Proceedings","Possible roles for glucocorticoids and apoptosis in the suppression of lymphopoiesis during zinc deficiency: a review","10.1080\u002F07315724.1995.10718467","Zinc regulates the function of two superantigens","10.1073\u002Fpnas.89.12.5507","Zinc suppresses apoptosis of U937 cells induced by hydrogen peroxide through an increase of the Bcl-2\u002F Bax ratio","10.1006\u002Fbbrc.1998.8621","Characterization of brain beta-carboline-2-N-methyltransferase, an enzyme that may play a role in idiopathic Parkinson's disease","Neurochemical Research","10.1023\u002FA:1027351120616","Ausschuß Nahrungsbedarf der DGE Zufuhrempfehlungen und Nährstoffbedarf. 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The effect of zinc supplementation","Renal Failure","10.3109\u002F08860229209047668","Effect of metal ions on diphteria toxin production","10.1128\u002Fiai.26.3.1065-1070.1979","The treatment of zinc is an immunotherapy","10.1016\u002F0192-0561(95)00062-7","Dimerization of cell surface receptors in signal transduction","Cell","10.1016\u002F0092-8674(95)90404-2","Reciprocity between tissue calmodulin and cAMP levels: modulation by excess zinc","British Journal of Dermatology","129","10.1111\u002Fj.1365-2133.1993.tb11847.x","Mechanisms of zinc uptake in gills of freshwater rainbow trout: interplay with calcium transport","270","The HDQVH-motif in domain E of the estradiol receptor alpha is responsible for zinc-binding and zinc-induced hormone release","Molecular and Cellular Endocrinology","10.1016\u002FS0303-7207(99)00089-1","Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1","Neuron","19","10.1016\u002FS0896-6273(00)80344-X","Zinc stimulates DNA synthesis during its antiapoptotic action independently with increments of an antiapoptotic protein, Bcl-2, in porcine kidney LLC-PK cells","Journal of Pharmacology and Experimental Therapeutics","Interaction between cytokines and α2-macroglobulin","163","10.1016\u002F0167-5699(90)90067-J","Zinc status in pregnancy: the effect of zinc therapy on perinatal mortality, prematurity, and placental ablation","10.1111\u002Fj.1749-6632.1993.tb26121.x","Lack of Ca2+ involvement in thymocyte apoptosis induced by chelation of intracellular Zn2+","Laboratory Investigation","111","Alzheimer's disease amyloid beta-protein forms Zn(2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons","Biophysical Journal","67","10.1016\u002FS0006-3495(97)78048-2","Zinc deficiency and immune function","Annual Review of Nutrition","10.1146\u002Fannurev.nu.10.070190.002215","Toxic shock syndrome toxin-1 complexed with a class II major histocompatibility molecule HLA-DR1","10.1126\u002Fscience.7997880","Stimulation of human peripheral lymphocytes by Zn2+ in vitro","Experimental Cell Research","10.1016\u002F0014-4827(70)90284-3","Urinary excretion of zinc and iron following acute injection of dead bacteria in dog","10.3181\u002F00379727-167-41143","Influence of heat shock protein 70 and metallothionein induction by zinc-bis-(DL-hydrogenaspartate) on the release of inflammatory mediators in a porcine model of recurrent endotoxemia","Biochemical Pharmacology","10.1016\u002F0006-2952(96)00469-8","Acrodermatitis enteropathica secondary to Crohn's disease","Dermatology","193","10.1159\u002F000246296","The impaired immune response to diphtheria vaccination in elderly chronic hemodialysis patients is related to zinc deficiency","Biogerontology","10.1023\u002FA:1010077622172","The significance of zinc for humoral and cellular immunity","Journal of Trace Elements and Electrolytes in Health and Diseases","Admission criteria for immunogerontological studies in man: The Senieur Protocol","10.1016\u002F0047-6374(84)90152-0","Amyloid beta protein (1–40) forms calcium permeable, Zn2+-sensitive channel in reconstituted lipid vesicles","Biochemistry","10.1021\u002Fbi982997c","Inhibitory sites in enzymes: Zinc removal and reactivation by thionein","10.1073\u002Fpnas.96.5.1936","10.1007\u002F978-1-4471-3879-2","Reversibility of the thymic involution and of age-related peripheral immune dysfunction by zinc supplementation in old mice","10.1016\u002F0192-0561(95)00059-B","Benefit of oral zinc supplementation as an adjunct to zidovudine (AZT) therapy against opportunistic infections in AIDS","10.1016\u002F0192-0561(95)00060-F","Zinc gluconate lozenges for treating the common cold","10.7326\u002F0003-4819-125-2-199607150-00001","cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene","10.1111\u002Fj.1432-1033.1996.00471.x","In vitro candidastatic properties of the human neutrophil calprotectin complex","10.4049\u002Fjimmunol.151.11.6291","Zinc deficiency manifested by dermatitis and visual dysfunction in a patient with Crohn's disease","Journal of Gastroenterology","879","10.1007\u002Fs005350050192","Zinc sulphate in the treatment of cutaneous leishmaniasis: an in vitro and animal study","Memorias do Instituto Oswaldo Cruz","10.1590\u002FS0074-02761998000600025","The transition to endoreduplication in trophoblast giant cells is regulated by the mSNA zinc finger transcription factor","Developmental Biology","10.1006\u002Fdbio.1998.8914","Zinc therapy in acrodermatitis enteropathica","New England Journal of Medicine","10.1056\u002FNEJM197504242921702","Improvement of the lymphoproliferative immune response and apoptosis inhibition upon in vitro treatment with zinc of peripheral blood mononuclear cells (PBMC) from HIV+ individuals","10.1046\u002Fj.1365-2249.1998.00495.x","Alterations in zinc homeostasis in depression and antidepressant therapy","Polish Journal of Pharmacology","Alterations in serum and brain trace element levels after antidepressant treatment: part I. Zinc","10.1007\u002FBF02784278","Transition metals in control of gene expression","715","10.1126\u002Fscience.8342038","Variance in the resistance of murine early bone marrow B cells to a deficiency in zinc","10.1046\u002Fj.1365-2567.1998.00076.x","Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc","10.1002\u002Fj.1460-2075.1995.tb07042.x","ZnT-2, a mammalian protein that confers resistance to zinc by facilitating vesicular sequestration","10.1002\u002Fj.1460-2075.1996.tb00527.x","ZnT-3, a putative transporter of zinc into synaptic vesicles","10.1073\u002Fpnas.93.25.14934","Zinc-induced copper deficiency: megamineral sideroblastic anemia","1985","10.7326\u002F0003-4819-103-3-385","Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers","10.1126\u002Fscience.8378770","A tale of three fingers: the family of mammalian Sp\u002FXKLF transcription factors","Nucleic Acids 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vaccination in elderly subjects: a randomized controlled trial","Age and Ageing","10.1093\u002Fageing\u002F27.6.715","The Ig-related killer cell inhibitory receptor binds zinc and requires zinc for recognition of HLA-C on target cells","10.4049\u002Fjimmunol.155.9.4143","Etudes chimique sur la vegetation (Chemical studies on plants)","Annales des Sciences Naturelles Botanique et Biologie Vegetale","Seroconversion rate hepatitis B vaccination, hemodialysis, and zinc supplementation","Kidney International","1987","Immunobiology of zinc and zinc therapy","10.1016\u002FS0167-5699(98)01400-5","Reply to Reinhold et al","10.1016\u002FS0167-5699(98)01401-7","Monocyte-dependent stimulation of human T cells by zinc","Kinetics of the Zn2+-stimulation of human peripheral lymphocytes in vitro","10.3181\u002F00379727-137-35733","Thymulin modulates cytokine release by peripheral blood mononuclear cells: a comparison between healthy volunteers and patients with systemic lupus erythematodes","International Archives of Allergy and Immunology","101","126","10.1159\u002F000236509","Zinc induces thymulin secretion from human thymic epithelial cells in vitro and augments splenocyte and thymocyte responses in vivo","10.1016\u002F0192-0561(95)00061-6","Selection of DNA binding sites for human transcriptional regulator GATA-6","10.1006\u002Fbbrc.1998.9374","Induction of interferon-γ in human leukocyte cultures stimulated by Zn2+","Clinical Immunology and Immunopathology","142","10.1016\u002F0090-1229(87)90120-6","A case of hyperzincemia with functional zinc depletion: a new disorder?","Pediatric Research","10.1203\u002F00006450-199708000-00015","Zinc nutriture in the elderly in relation to taste acuity, immune response, and wound healing","10.1093\u002Fajcn\u002F36.5.1046","Differential DNA binding by the androgen and glucocorticoid receptors involves the second Zn-finger and a C-terminal extension of the DNA-binding domains","Biochemical Journal","521","10.1042\u002Fbj3410515","Low zinc intake during pregnancy: its association with preterm and very preterm delivery","American Journal of Epidemiology","10.1093\u002Foxfordjournals.aje.a116615","Identification of the serum binding proteins for iron, zinc, cadmium, nickel and calcium","Clinical Chemistry","10.1093\u002Fclinchem\u002F29.4.629","Differential effects of copper and zinc on human peripheral blood monocyte cytokine secretion","10.1016\u002F0008-8749(90)90330-T","Treatment and management of Wilson's disease","Pediatrics International","10.1046\u002Fj.1442-200x.1999.01093.x","Oral zinc sulphate in rheumatoid arthritis","10.1016\u002FS0140-6736(76)91793-1","A zinc-finger-type transcription factor WZF-1 that binds to a novel cis-acting element of histone gene promoters represses its own promoter","Plant and Cellular Physiology","10.1093\u002Foxfordjournals.pcp.a028980","The zinc-reversible antimicrobial activity of neutrophil lysates and abscess fluid supernatants","10.1093\u002Finfdis\u002F164.1.137","RFLAT-1: a new zinc finger transcription factor that activates RANTES gene expression in T lymphocytes","Immunity","10.1016\u002FS1074-7613(00)80010-2","Characterization of zinc-depleted alanyl-tRNA synthetase from Escherichia coli: role of zinc","Archives of Biochemistry and Biophysics","10.1006\u002Fabbi.1999.1314","Zinc therapy increases duodenal concentrations of metallothionein and iron in Wilson's disease patients","American Journal of Gastroenterology","10.1111\u002Fj.1572-0241.1999.851_w.x","The crystal structure of staphylococcal enterotoxin type D reveals Zn2+ mediated homodimerization","10.1002\u002Fj.1460-2075.1996.tb01074.x","Zinc inhibits pokeweed mitogen-induced development of immunoglobulin-secreting cells through augmentation of both CD4 and CD8 cells","10.1016\u002F0192-0561(89)90153-7","Zinc inhibits turnover of labile mRNAs in intact cells","Journal of Cellular Physiology","378","10.1002\u002Fjcp.1041620310","An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy","Nature Genetics","10.1038\u002Fng1297-399","In vitro amplification of toxic shock syndrome toxin-1 by intravaginal devices","Contraception","10.1016\u002F0010-7824(85)90033-2","Zinc in the nutrition of the rat","156","10.1152\u002Fajplegacy.1933.107.1.146","Programmed cell death of peripheral myeloid precursor cells in Down patients: effect of zinc therapy","10.3109\u002F01913129609016349","Expression of zinc transporter gene, ZnT-1, is induced after transient forebrain ischemia in the gerbil","Journal of Neuroscience","10.1523\u002FJNEUROSCI.17-17-06678.1997","Effects of zinc supplementation on the immune system and on antibody response to multivalent influenza vaccine in hemodialysis patients","International Journal of Artificial Organs","10.1177\u002F039139889802100508","Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators","10.1093\u002Femboj\u002F17.17.5129","Screening for inducers of apoptosis in apoptosis-resistant human carcinoma cells","Advances in Enzyme Regulation","10.1016\u002FS0065-2571(98)00022-3","Effect of iron, tin and copper on zinc absorption in humans","10.1093\u002Fajcn\u002F40.3.536","The biochemical basis of zinc physiology","Physiological Reviews","79","10.1152\u002Fphysrev.1993.73.1.79","Mode of action of Zn-complexes on herpes simplex virus type 1 infection in vitro","Journal of Chemotherapy","10.1080\u002F1120009X.1993.11739200","Involvement of the Zn-binding region of the tetanus toxin in B and T recognition. 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