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class="l-content" role="main"> <a id="main-content"></a> <div id="block-views-nih-rm-featured-article-block" class="block block--views teaser-list-featured block--views-nih-rm-featured-article-block" id="block-views-nih-rm-featured-article-block" class="block block--views teaser-list-featured block--views-nih-rm-featured-article-block"> <div class="content" class="block__content"> <div class="view view-nih-rm-featured-article view-id-nih_rm_featured_article view-display-id-block view-dom-id-e105fa03b0e4966ef43864991e0c7805"> <div class="view-header"> <h3 class="header-with-rule top"> February 18, 2025 Edition</h3> </div> <div class="view-content"> <div class="teaser-featured teaser-clickable"> <div> <div class="teaser-thumbnail"><div id="file-84821" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2025/20250211-alz.jpg">20250211-alz.jpg</a></h2> <div class="content"> <picture title="Group of senior male and female friends doing a puzzle together at a table. ">  <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/news-events/research-matters/2025/20250211-alz.jpg?itok=-uk77obL&timestamp=1739445102 1x" media="screen and (min-width: 800px)" /> <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/news-events/research-matters/2025/20250211-alz.jpg?itok=t1_rkHPz&timestamp=1739445102 1x" media="screen and (min-width: 600px)" /> <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/news-events/research-matters/2025/20250211-alz.jpg?itok=qOjThkgG&timestamp=1739445102 1x" media="screen and (min-width: 480px)" /> <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/news-events/research-matters/2025/20250211-alz.jpg?itok=0NJfmjh5&timestamp=1739445102 1x" media="screen and (min-width: 0)" />  <img src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/news-events/research-matters/2025/20250211-alz.jpg?itok=-uk77obL&timestamp=1739445102" alt="Group of senior male and female friends doing a puzzle together at a table. " title="Group of senior male and female friends doing a puzzle together at a table. " /> </picture> </div> </div> </div> </div> <div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/risk-future-burden-dementia-united-states">Risk and future burden of dementia in the United States </a></h4> </div> <div> <div><p class="teaser-description">Researchers estimated that 42% of Americans over age 55 will eventually develop dementia.</p></div> </div> </div> <div class="teaser-featured teaser-clickable"> <div> <div class="teaser-thumbnail"><div id="file-84816" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2025/20250211-contact.jpg">20250211-contact.jpg</a></h2> <div class="content"> <picture title="Teen putting a contact in her eye.">  <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/news-events/research-matters/2025/20250211-contact.jpg?itok=DD1mHKDL&timestamp=1739887693 1x" media="screen and (min-width: 800px)" /> <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/news-events/research-matters/2025/20250211-contact.jpg?itok=YNx_WX2b&timestamp=1739887693 1x" media="screen and (min-width: 600px)" /> <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/news-events/research-matters/2025/20250211-contact.jpg?itok=0VXJSvVe&timestamp=1739887693 1x" media="screen and (min-width: 480px)" /> <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/news-events/research-matters/2025/20250211-contact.jpg?itok=rchVDRab&timestamp=1739887693 1x" media="screen and (min-width: 0)" />  <img src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/news-events/research-matters/2025/20250211-contact.jpg?itok=DD1mHKDL&timestamp=1739887693" alt="Teen putting a contact in her eye." title="Teen putting a contact in her eye." /> </picture> </div> </div> </div> </div> <div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/lasting-effects-contact-lenses-slow-myopia-kids">Lasting effects of contact lenses that slow myopia in kids</a></h4> </div> <div> <div><p class="teaser-description">Multifocal contact lenses slowed progression of nearsightedness in children, and the treatment benefit continued even after they stopped wearing the lenses. </p></div> </div> </div> <div class="teaser-featured teaser-clickable"> <div> <div class="teaser-thumbnail"><div id="file-84811" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2025/20250211-malaria.jpg">20250211-malaria.jpg</a></h2> <div class="content"> <picture title="Red blood cell infected with malaria parasites.">  <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/news-events/research-matters/2025/20250211-malaria.jpg?itok=5JQ1ASFM&timestamp=1739445129 1x" media="screen and (min-width: 800px)" /> <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium-small/public/news-events/research-matters/2025/20250211-malaria.jpg?itok=GiefhpuX&timestamp=1739445129 1x" media="screen and (min-width: 600px)" /> <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-small/public/news-events/research-matters/2025/20250211-malaria.jpg?itok=Q0ZWeJNw&timestamp=1739445129 1x" media="screen and (min-width: 480px)" /> <source srcset="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-tiny/public/news-events/research-matters/2025/20250211-malaria.jpg?itok=cmMIwY3R&timestamp=1739445129 1x" media="screen and (min-width: 0)" />  <img src="https://www.nih.gov/sites/default/files/styles/feature_teaser_breakpoint-medium/public/news-events/research-matters/2025/20250211-malaria.jpg?itok=5JQ1ASFM&timestamp=1739445129" alt="Colorized scanning electron micrograph of red blood cells. The one infected by malaria parasites has a rough surface, while the others are smooth. " title="Red blood cell infected with malaria parasites." /> </picture> </div> </div> </div> </div> <div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/potential-new-target-malaria-discovered">Potential new target for malaria discovered</a></h4> </div> <div> <div><p class="teaser-description">Researchers identified antibodies that bind to a previously untargeted portion of the malaria parasite.</p></div> </div> </div> </div> </div> </div> </div> <div id="block-views-nih-rm-archive-block" class="block block--views research-matters-more-stories block--views-nih-rm-archive-block" id="block-views-nih-rm-archive-block" class="block block--views research-matters-more-stories block--views-nih-rm-archive-block"> <div class="content" class="block__content"> <div class="view view-nih-rm-archive view-id-nih_rm_archive view-display-id-block view-dom-id-1bc4ab8c353e9cc0abd9b6b7fb13f9f5"> <div class="view-header"> <h3 id="morestories">More Stories</h3> <ul class="inline-link-list"> <li><a href="/news-events/nih-research-matters#morestories">All</a></li> <li><a href="/news-events/nih-research-matters?2024#morestories">2024</a></li> <li><a href="/news-events/nih-research-matters?2023#morestories">2023</a></li> <li><a href="/news-events/nih-research-matters?2022#morestories">2022</a></li> <li><a href="/news-events/nih-research-matters?2021#morestories">2021</a></li> <li><a href="/news-events/nih-research-matters?2020#morestories">2020</a></li> <li><a href="/news-events/nih-research-matters?2019#morestories">2019</a></li> <li><a href="/news-events/nih-research-matters?2018#morestories">2018</a></li> <li><a href="/news-events/nih-research-matters?2017#morestories">2017</a></li> <li><a href="/news-events/nih-research-matters?2016#morestories">2016</a></li> <li><a href="/news-events/nih-research-matters?2015#morestories">2015</a></li> <li><a href="/news-events/nih-research-matters?2014#morestories">2014</a></li> <li><a href="/news-events/nih-research-matters?2013#morestories">2013</a></li> <li><a href="/news-events/nih-research-matters?2012#morestories">2012</a></li> <li><a href="/news-events/nih-research-matters?2011#morestories">2011</a></li> <li><a href="/news-events/nih-research-matters?2010#morestories">2010</a></li> <li><a href="/news-events/nih-research-matters?2009#morestories">2009</a></li> <li><a href="/news-events/nih-research-matters?2008#morestories">2008</a></li> <li><a href="/news-events/nih-research-matters?2007#morestories">2007</a></li> <li><a href="/news-events/nih-research-matters?2006#morestories">2006</a></li> </ul> </div> <div class="view-content"> <ul class="teaser-list teaser-list-no-grid"> <li class="teaser teaser-clickable"> <div class="teaser-thumbnail"><div id="file-84576" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2025/20250121-blood.jpg">20250121-blood.jpg</a></h2> <div class="content"> <img typeof="foaf:Image" src="https://www.nih.gov/sites/default/files/styles/thumbnail/public/news-events/research-matters/2025/20250121-blood.jpg?itok=w8gWIkrt" width="150" height="150" alt="Doctor preparing a woman’s arm for a blood test." title="Doctor preparing a woman’s arm for a blood test." /> </div> </div> </div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/research-context-detecting-cancer" target="_blank">Research in Context: Detecting cancer</a></h4> <p class="teaser-description"><span property="dc:date" datatype="xsd:dateTime" content="2025-02-13T00:00:00-05:00" class="date-display-single">February 13, 2025</span> — Researchers have made huge strides in learning how to detect signs of cancer in bodily fluids like blood, saliva, and urine. Learn how these liquid biopsies are being tested to aid early cancer detection and guide treatment. </p> </li> <li class="teaser teaser-clickable"> <div class="teaser-thumbnail"><div id="file-84471" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2025/20250114-cancer.jpg">20250114-cancer.jpg</a></h2> <div class="content"> <img typeof="foaf:Image" src="https://www.nih.gov/sites/default/files/styles/thumbnail/public/news-events/research-matters/2025/20250114-cancer.jpg?itok=5iLorroe" width="150" height="150" alt="Female doctor speaking with an elderly female patient while looking at test results." title="Female doctor speaking with an elderly female patient while looking at test results." /> </div> </div> </div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/prevention-screening-drive-drop-cancer-deaths" target="_blank">Prevention and screening drive drop in cancer deaths</a></h4> <p class="teaser-description"><span property="dc:date" datatype="xsd:dateTime" content="2025-01-14T00:00:00-05:00" class="date-display-single">January 14, 2025</span> — Most deaths avoided from common cancers between 1975 and 2020 could be traced to prevention and screening efforts. </p> </li> <li class="teaser teaser-clickable"> <div class="teaser-thumbnail"><div id="file-84466" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2025/20250114-flu.jpg">20250114-flu.jpg</a></h2> <div class="content"> <img typeof="foaf:Image" src="https://www.nih.gov/sites/default/files/styles/thumbnail/public/news-events/research-matters/2025/20250114-flu.jpg?itok=-t2D2HW2" width="150" height="150" alt="Electron microscope image shows several rounded influenza virus particles with outer layers." title="Electron microscope image shows several rounded influenza virus particles with outer layers." /> </div> </div> </div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/building-better-flu-vaccine" target="_blank">Building a better flu vaccine</a></h4> <p class="teaser-description"><span property="dc:date" datatype="xsd:dateTime" content="2025-01-14T00:00:00-05:00" class="date-display-single">January 14, 2025</span> — A vaccine made by connecting antigens from different flu strains together elicited a more broadly protective immune response than a conventional flu vaccine. </p> </li> <li class="teaser teaser-clickable"> <div class="teaser-thumbnail"><div id="file-84461" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2025/20250114-cholesterol.jpg">20250114-cholesterol.jpg</a></h2> <div class="content"> <img typeof="foaf:Image" src="https://www.nih.gov/sites/default/files/styles/thumbnail/public/news-events/research-matters/2025/20250114-cholesterol.jpg?itok=1iBDHpcy" width="150" height="150" alt="Illustration shows apoB100 has a ladder-like belt and an overall rounded structure that enables it to hold a cargo of lipid." title="Illustration shows apoB100 has a ladder-like belt and an overall rounded structure that enables it to hold a cargo of lipid." /> </div> </div> </div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/lipoprotein-structure-gives-insights-into-bad-cholesterol" target="_blank">Lipoprotein structure gives insights into “bad” cholesterol</a></h4> <p class="teaser-description"><span property="dc:date" datatype="xsd:dateTime" content="2025-01-14T00:00:00-05:00" class="date-display-single">January 14, 2025</span> — Researchers uncovered the structural details of how low-density lipoprotein (LDL), or “bad,” cholesterol, interacts with its receptor molecule to enter cells. </p> </li> <li class="teaser teaser-clickable"> <div class="teaser-thumbnail"><div id="file-81396" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2024/20240611-peanut.jpg">20240611-peanut.jpg</a></h2> <div class="content"> <img typeof="foaf:Image" src="https://www.nih.gov/sites/default/files/styles/thumbnail/public/news-events/research-matters/2024/20240611-peanut.jpg?itok=TbBeB4gp" width="150" height="150" alt="Father with young son on his lap spreading peanut butter on toast." title="Father with young son on his lap spreading peanut butter on toast." /> </div> </div> </div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/2024-nih-research-highlights-human-health-advances" target="_blank">2024 NIH Research Highlights - Human Health Advances</a></h4> <p class="teaser-description"><span property="dc:date" datatype="xsd:dateTime" content="2024-12-18T00:00:00-05:00" class="date-display-single">December 18, 2024</span> — NIH accomplishments in disease prevention, diagnosis, and treatment include an accurate blood test for Alzheimer’s disease, progress in food allergy prevention and treatment, and a brain-computer interface that helped a paralyzed man speak. </p> </li> <li class="teaser teaser-clickable"> <div class="teaser-thumbnail"><div id="file-81916" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2024/20240715-prion.jpg">20240715-prion</a></h2> <div class="content"> <img typeof="foaf:Image" src="https://www.nih.gov/sites/default/files/styles/thumbnail/public/news-events/research-matters/2024/8656058266_94c1dafae3_o.jpg?itok=tZDySYsq" width="150" height="150" alt="Colorized electron micrograph of prion protein fibrils." title="Colorized electron micrograph of prion protein fibrils." /> </div> </div> </div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/2024-nih-research-highlights-promising-medical-findings" target="_blank">2024 NIH Research Highlights - Promising Medical Findings</a></h4> <p class="teaser-description"><span property="dc:date" datatype="xsd:dateTime" content="2024-12-18T00:00:00-05:00" class="date-display-single">December 18, 2024</span> — NIH findings with potential for enhancing human health include insights into the mechanisms of ME/CFS, a skin test to detect Parkinson’s disease and related disorders, and a promising target for cataract drug development. </p> </li> <li class="teaser teaser-clickable"> <div class="teaser-thumbnail"><div id="file-81181" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2024/20240521-synapses.jpg">20240521-synapses.jpg</a></h2> <div class="content"> <img typeof="foaf:Image" src="https://www.nih.gov/sites/default/files/styles/thumbnail/public/news-events/research-matters/2024/20240521-synapses.jpg?itok=C1gmASMq" width="150" height="150" alt="Image of a large white nerve cell with long projections that are covered with green spots (synapses) and fine webbing of blue fibers, representing axons." title="Image of a large white nerve cell with long projections that are covered with green spots (synapses) and fine webbing of blue fibers, representing axons." /> </div> </div> </div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/2024-nih-research-highlights-basic-research-insights" target="_blank">2024 NIH Research Highlights - Basic Research Insights</a></h4> <p class="teaser-description"><span property="dc:date" datatype="xsd:dateTime" content="2024-12-18T00:00:00-05:00" class="date-display-single">December 18, 2024</span> — Noteworthy NIH advances in basic research include insights into the H5N1 avian influenza outbreak, mapping how cancers form and spread, and progress in understanding the brain. </p> </li> <li class="teaser teaser-clickable"> <div class="teaser-thumbnail"><div id="file-83946" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2024/20241210-fire.jpeg">20241210-fire.jpeg</a></h2> <div class="content"> <img typeof="foaf:Image" src="https://www.nih.gov/sites/default/files/styles/thumbnail/public/news-events/research-matters/2024/20241210-fire.jpeg?itok=SNaOuGjO" width="150" height="150" alt="A lone car far in the distance travels on a highway away from a large, blazing forest fire." title="A lone car far in the distance travels on a highway away from a large, blazing forest fire." /> </div> </div> </div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/wildfire-smoke-exposure-dementia-risk" target="_blank">Wildfire smoke exposure and dementia risk</a></h4> <p class="teaser-description"><span property="dc:date" datatype="xsd:dateTime" content="2024-12-10T00:00:00-05:00" class="date-display-single">December 10, 2024</span> — Wildfire smoke exposure was associated with greater odds of being diagnosed with dementia. </p> </li> <li class="teaser teaser-clickable"> <div class="teaser-thumbnail"><div id="file-83951" class="file file-image file-image-jpeg" class="file file-image file-image-jpeg"> <h2 class="element-invisible"><a href="/2024/20241210-breast-tissue.jpeg">20241210-breast-tissue.jpeg</a></h2> <div class="content"> <img typeof="foaf:Image" src="https://www.nih.gov/sites/default/files/styles/thumbnail/public/news-events/research-matters/2024/20241210-breast-tissue.jpeg?itok=bgx-Hga4" width="150" height="150" alt="Doctor speaking with a female patient." title="Doctor speaking with a female patient." /> </div> </div> </div> <h4 class="teaser-title"><a href="/news-events/nih-research-matters/chromosome-abnormalities-found-healthy-breast-tissue" target="_blank">Chromosome abnormalities found in healthy breast tissue</a></h4> <p class="teaser-description"><span property="dc:date" datatype="xsd:dateTime" content="2024-12-10T00:00:00-05:00" class="date-display-single">December 10, 2024</span> — Researchers found that normal human breast tissue harbors rare cells with chromosome abnormalities previously linked to invasive cancers. 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