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class="vector-toc-link" href="#Funkció"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Funkció</span> </div> </a> <ul id="toc-Funkció-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Koenzim-A_által_aktivált_acilcsoportok" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Koenzim-A_által_aktivált_acilcsoportok"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Koenzim-A által aktivált acilcsoportok</span> </div> </a> <ul id="toc-Koenzim-A_által_aktivált_acilcsoportok-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Szerkezet" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Szerkezet"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Szerkezet</span> </div> </a> <ul id="toc-Szerkezet-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Források" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Források"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Források</span> </div> </a> <ul id="toc-Források-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Tartalomjegyzék" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Tartalomjegyzék kinyitása/becsukása" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Tartalomjegyzék kinyitása/becsukása</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Koenzim-A</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Ugrás egy más nyelvű szócikkre. Elérhető 37 nyelven" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-37" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">37 nyelv</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Coenzyme_A" title="Coenzyme A – angol" lang="en" hreflang="en" data-title="Coenzyme A" data-language-autonym="English" data-language-local-name="angol" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%85%D8%B1%D8%A7%D9%81%D9%82_%D8%A7%D9%84%D8%A5%D9%86%D8%B2%D9%8A%D9%85-%D8%A3" title="مرافق الإنزيم-أ – arab" lang="ar" hreflang="ar" data-title="مرافق الإنزيم-أ" data-language-autonym="العربية" data-language-local-name="arab" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%DA%A9%D9%88%D8%A2%D9%86%D8%B2%DB%8C%D9%88%D9%85_%D8%A2" title="کوآنزیوم آ – South Azerbaijani" lang="azb" hreflang="azb" data-title="کوآنزیوم آ" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Koenzim_A" title="Koenzim A – bosnyák" lang="bs" hreflang="bs" data-title="Koenzim A" data-language-autonym="Bosanski" data-language-local-name="bosnyák" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Coenzim_A" title="Coenzim A – katalán" lang="ca" hreflang="ca" data-title="Coenzim A" data-language-autonym="Català" data-language-local-name="katalán" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Koenzym_A" title="Koenzym A – cseh" lang="cs" hreflang="cs" data-title="Koenzym A" data-language-autonym="Čeština" data-language-local-name="cseh" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Coenzym_A" title="Coenzym A – német" lang="de" hreflang="de" data-title="Coenzym A" data-language-autonym="Deutsch" data-language-local-name="német" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Coenzima_A" title="Coenzima A – spanyol" lang="es" hreflang="es" data-title="Coenzima A" data-language-autonym="Español" data-language-local-name="spanyol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Koens%C3%BC%C3%BCm_A" title="Koensüüm A – észt" lang="et" hreflang="et" data-title="Koensüüm A" data-language-autonym="Eesti" data-language-local-name="észt" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/A_koentzima" title="A koentzima – baszk" lang="eu" hreflang="eu" data-title="A koentzima" data-language-autonym="Euskara" data-language-local-name="baszk" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%DA%A9%D9%88%D8%A2%D9%86%D8%B2%DB%8C%D9%85_%D8%A2" title="کوآنزیم آ – perzsa" lang="fa" hreflang="fa" data-title="کوآنزیم آ" data-language-autonym="فارسی" data-language-local-name="perzsa" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Koentsyymi_A" title="Koentsyymi A – finn" lang="fi" hreflang="fi" data-title="Koentsyymi A" data-language-autonym="Suomi" data-language-local-name="finn" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Coenzyme_A" title="Coenzyme A – francia" lang="fr" hreflang="fr" data-title="Coenzyme A" data-language-autonym="Français" data-language-local-name="francia" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Coencima_A" title="Coencima A – gallego" lang="gl" hreflang="gl" data-title="Coencima A" data-language-autonym="Galego" data-language-local-name="gallego" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%A7%D7%95%D7%90%D7%A0%D7%96%D7%99%D7%9D_A" title="קואנזים A – héber" lang="he" hreflang="he" data-title="קואנזים A" data-language-autonym="עברית" data-language-local-name="héber" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Koenzim_A" title="Koenzim A – horvát" lang="hr" hreflang="hr" data-title="Koenzim A" data-language-autonym="Hrvatski" data-language-local-name="horvát" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Koenzim_A" title="Koenzim A – indonéz" lang="id" hreflang="id" data-title="Koenzim A" data-language-autonym="Bahasa Indonesia" data-language-local-name="indonéz" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Coenzima_A" title="Coenzima A – olasz" lang="it" hreflang="it" data-title="Coenzima A" data-language-autonym="Italiano" data-language-local-name="olasz" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E8%A3%9C%E9%85%B5%E7%B4%A0A" title="補酵素A – japán" lang="ja" hreflang="ja" data-title="補酵素A" data-language-autonym="日本語" data-language-local-name="japán" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%A1%B0%ED%9A%A8%EC%86%8C_A" title="조효소 A – koreai" lang="ko" hreflang="ko" data-title="조효소 A" data-language-autonym="한국어" data-language-local-name="koreai" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Kofermentas_A" title="Kofermentas A – litván" lang="lt" hreflang="lt" data-title="Kofermentas A" data-language-autonym="Lietuvių" data-language-local-name="litván" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%9A%D0%BE%D0%B5%D0%BD%D0%B7%D0%B8%D0%BC_%D0%90" title="Коензим А – macedón" lang="mk" hreflang="mk" data-title="Коензим А" data-language-autonym="Македонски" data-language-local-name="macedón" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Koenzim_A" title="Koenzim A – maláj" lang="ms" hreflang="ms" data-title="Koenzim A" data-language-autonym="Bahasa Melayu" data-language-local-name="maláj" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-oc mw-list-item"><a href="https://oc.wikipedia.org/wiki/Coenzim_A" title="Coenzim A – okszitán" lang="oc" hreflang="oc" data-title="Coenzim A" data-language-autonym="Occitan" data-language-local-name="okszitán" class="interlanguage-link-target"><span>Occitan</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Koenzym_A" title="Koenzym A – lengyel" lang="pl" hreflang="pl" data-title="Koenzym A" data-language-autonym="Polski" data-language-local-name="lengyel" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Coenzima_A" title="Coenzima A – portugál" lang="pt" hreflang="pt" data-title="Coenzima A" data-language-autonym="Português" data-language-local-name="portugál" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Coenzima_A" title="Coenzima A – román" lang="ro" hreflang="ro" data-title="Coenzima A" data-language-autonym="Română" data-language-local-name="román" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9A%D0%BE%D1%84%D0%B5%D1%80%D0%BC%D0%B5%D0%BD%D1%82_A" title="Кофермент A – orosz" lang="ru" hreflang="ru" data-title="Кофермент A" data-language-autonym="Русский" data-language-local-name="orosz" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Koenzim_A" title="Koenzim A – szerbhorvát" lang="sh" hreflang="sh" data-title="Koenzim A" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="szerbhorvát" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Coenzyme_A" title="Coenzyme A – Simple English" lang="en-simple" hreflang="en-simple" data-title="Coenzyme A" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Koenz%C3%BDm_A" title="Koenzým A – szlovák" lang="sk" hreflang="sk" data-title="Koenzým A" data-language-autonym="Slovenčina" data-language-local-name="szlovák" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Koenzim_A" title="Koenzim A – szerb" lang="sr" hreflang="sr" data-title="Koenzim A" data-language-autonym="Српски / srpski" data-language-local-name="szerb" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Koenzym_A" title="Koenzym A – svéd" lang="sv" hreflang="sv" data-title="Koenzym A" data-language-autonym="Svenska" data-language-local-name="svéd" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Koenzim_A" title="Koenzim A – török" lang="tr" hreflang="tr" data-title="Koenzim A" data-language-autonym="Türkçe" data-language-local-name="török" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9A%D0%BE%D1%84%D0%B5%D1%80%D0%BC%D0%B5%D0%BD%D1%82_A" title="Кофермент A – ukrán" lang="uk" hreflang="uk" data-title="Кофермент A" data-language-autonym="Українська" data-language-local-name="ukrán" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Coenzyme_A" title="Coenzyme A – vietnámi" lang="vi" hreflang="vi" data-title="Coenzyme A" data-language-autonym="Tiếng Việt" data-language-local-name="vietnámi" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E8%BE%85%E9%85%B6A" title="辅酶A – kínai" lang="zh" hreflang="zh" data-title="辅酶A" data-language-autonym="中文" data-language-local-name="kínai" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q407635#sitelinks-wikipedia" title="Nyelvközi hivatkozások szerkesztése" class="wbc-editpage">Hivatkozások szerkesztése</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Névterek"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Koenzim-A" title="A lap megtekintése [c]" accesskey="c"><span>Szócikk</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Vita:Koenzim-A" rel="discussion" title="Az oldal tartalmának megvitatása [t]" accesskey="t"><span>Vitalap</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" 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							cdx-fr-css-icon--close"></span></button></header><div class="cdx-dialog__body">Ez a <a href="/wiki/Wikip%C3%A9dia:Jel%C3%B6lt_lapv%C3%A1ltozatok" title="Wikipédia:Jelölt lapváltozatok">közzétett változat</a>, <a class="external text" href="https://hu.wikipedia.org/w/index.php?title=Speci%C3%A1lis:Rendszernapl%C3%B3k&type=review&page=Speci%C3%A1lis:Badtitle/Message">ellenőrizve</a>: <i>2022. június 17.</i><p><table id="mw-fr-revisionratings-box" class="flaggedrevs-color-1" style="margin: auto;" cellpadding="0"><tr><td class="fr-text" style="vertical-align: middle;">Pontosság</td><td class="fr-value40" style="vertical-align: middle;">ellenőrzött</td></tr></table></p></div></div><div tabindex="0"></div></div></div></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="hu" dir="ltr"><table class="toccolours" border="1" width="300" style="float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;"> <tbody><tr> <td colspan="2" style="background-color: #F8EABA; padding: 0.5em" align="center"><b><font style="font-size: larger">Koenzim-A</font></b> </td></tr> <tr> <td colspan="2" align="center"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Coenzym_A.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Coenzym_A.svg/300px-Coenzym_A.svg.png" decoding="async" width="300" height="122" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Coenzym_A.svg/450px-Coenzym_A.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e9/Coenzym_A.svg/600px-Coenzym_A.svg.png 2x" data-file-width="845" data-file-height="343" /></a></span> </td></tr> <tr> <td colspan="2" align="center"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Coenzyme-A-3D-balls.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Coenzyme-A-3D-balls.png/300px-Coenzyme-A-3D-balls.png" decoding="async" width="300" height="117" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Coenzyme-A-3D-balls.png/450px-Coenzyme-A-3D-balls.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Coenzyme-A-3D-balls.png/600px-Coenzyme-A-3D-balls.png 2x" data-file-width="1100" data-file-height="429" /></a></span> </td></tr> <tr> <th colspan="2" style="background-color: #F8EABA; padding: 0.5em" align="center"><b>Kémiai azonosítók</b> </th></tr> <tr> <td><a href="/wiki/CAS-sz%C3%A1m" title="CAS-szám">CAS-szám</a></td> <td><span class="reflink plainlinks"><a rel="nofollow" class="external text" href="http://www.emolecules.com/cgi-bin/search?t=ss&q=85-61-0&c=1&v=">85-61-0</a></span> </td></tr> <tr> <td><a href="/wiki/PubChem" title="PubChem">PubChem</a></td> <td><span class="reflink plainlinks"><a rel="nofollow" class="external text" href="http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=317">317</a></span> </td></tr> <tr> <td><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></td> <td><span class="reflink plainlinks"><a rel="nofollow" class="external text" href="http://www.chemspider.com/79067">79067</a></span> </td></tr> <tr> <td><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a></td> <td><span class="reflink plainlinks"><a rel="nofollow" class="external text" href="http://www.nlm.nih.gov/cgi/mesh/2007/MB_cgi?mode=&term=Coenzyme+A">Coenzyme+A</a></span> </td></tr> <tr> <th colspan="2" style="background-color: #F8EABA; padding: 0.5em" align="center"><b>Kémiai és fizikai tulajdonságok</b> </th></tr> <tr> <td><a href="/wiki/K%C3%A9miai_k%C3%A9plet" title="Kémiai képlet">Kémiai képlet</a></td> <td>C<sub>21</sub>H<sub>36</sub>N<sub>7</sub>O<sub>16</sub>P<sub>3</sub>S </td></tr> <tr> <td><a href="/wiki/Mol%C3%A1ris_t%C3%B6meg" title="Moláris tömeg">Moláris tömeg</a></td> <td>767,535 g/mol </td></tr> <tr> <td align="center" style="background-color: #F8EABA; padding: 0.5em" colspan="2"><small>Ha másként nem jelöljük, az adatok az anyag <a href="/wiki/Standard%C3%A1llapot" title="Standardállapot">standardállapotára</a> (100 kPa) és 25 °C-os hőmérsékletre vonatkoznak.</small> </td></tr></tbody></table> <p>A <b>koenzim-A</b> (<b>CoA</b>, <b>CoASH</b>, vagy <b>HSCoA</b>) egy <a href="/wiki/Koenzim" class="mw-redirect" title="Koenzim">koenzim</a>, amely a zsírsavszintézis, a zsírsavoxidáció és a piruvát oxidáció (<a href="/wiki/Citromsavciklus" title="Citromsavciklus">citromsavciklus</a>) folyamataiban vesz részt. A <a href="/wiki/Feh%C3%A9rje" title="Fehérje">fehérjék</a> könnyen leválasztható része, egy nem-fehérje enzimalkotó; vagyis koenzim. <a href="/wiki/Acilcsoport" title="Acilcsoport">Acilcsoportokat</a> (RCO-) szállít. </p><p>Az emberi szervezet <a href="/wiki/Cisztein" title="Cisztein">ciszteinből</a>, <a href="/wiki/Pantot%C3%A9nsav" title="Pantoténsav">pantoténsavból</a> (B5-vitamin) és <a href="/wiki/Adenozin-trifoszf%C3%A1t" title="Adenozin-trifoszfát">ATP</a>-ből állítja elő. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Bioszintézis"><span id="Bioszint.C3.A9zis"></span>Bioszintézis</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Koenzim-A&action=edit&section=1" title="Szakasz szerkesztése: Bioszintézis"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>A koenzim-A ötlépcsős folyamatban képződik pantoténsavból. </p> <ol><li>a pantotenát-kináz enzim segítségével a pantotenát 4′-foszfopantotenáttá foszforilálódik</li> <li>a foszfopantotenoil-cisztein-szintetáz enzim segítségével cisztein kapcsolódik a 4′-foszfopantotenáthoz és 4′-foszfo-<i>N</i>-pantotenoil-cisztein (PPC) képződik</li> <li>a PPC a <a href="/w/index.php?title=Foszfopantotenoil-cisztein_dekarboxil%C3%A1z&action=edit&redlink=1" class="new" title="Foszfopantotenoil-cisztein dekarboxiláz (a lap nem létezik)">foszfopantotenoil-cisztein dekarboxiláz</a> enzim segítségével 4′-foszfopantetein-né dekarboxilálódik</li> <li>a 4′-foszfopantetein defoszfo-CoA-vá adenilálódik a <a href="/w/index.php?title=Foszfopantetein-adenilil-transzfer%C3%A1z&action=edit&redlink=1" class="new" title="Foszfopantetein-adenilil-transzferáz (a lap nem létezik)">foszfopantetein-adenilil-transzferáz</a> enzim által.</li> <li>végül a defoszfo-CoA a <a href="/w/index.php?title=Defoszfo-koenzim-A_kin%C3%A1z&action=edit&redlink=1" class="new" title="Defoszfo-koenzim-A kináz (a lap nem létezik)">defoszfo-koenzim-A kináz</a> enzim és <a href="/wiki/Adenozin-trifoszf%C3%A1t" title="Adenozin-trifoszfát">ATP</a> hatására koenzim-A-vá foszforilálódik.</li></ol> <div class="mw-heading mw-heading2"><h2 id="Funkció"><span id="Funkci.C3.B3"></span>Funkció</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Koenzim-A&action=edit&section=2" title="Szakasz szerkesztése: Funkció"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Mivel a koenzim-A egy <a href="/wiki/Tiol" class="mw-redirect" title="Tiol">tiol</a>, <a href="/wiki/Karbonsavak" title="Karbonsavak">karbonsavakkal</a> <a href="/wiki/Tio%C3%A9szter" title="Tioészter">tioésztereket</a> képezhet, tehát <a href="/wiki/Acilcsoport" title="Acilcsoport">acilcsoportot</a> képes szállítani. </p><p>Az acetilcsoportot szállító koenzim-A-molekulát <a href="/wiki/Acetil-koenzim-A" title="Acetil-koenzim-A">acetil-koenzim-A</a>-nak (acetil-CoA) nevezik. Ha nem kapcsolódik hozzá acilcsoport, egyszerűen CoA-ként, vagy CoASH-ként, HSCoA-ként jelölik. </p> <div class="mw-heading mw-heading2"><h2 id="Koenzim-A_által_aktivált_acilcsoportok"><span id="Koenzim-A_.C3.A1ltal_aktiv.C3.A1lt_acilcsoportok"></span>Koenzim-A által aktivált acilcsoportok</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Koenzim-A&action=edit&section=3" title="Szakasz szerkesztése: Koenzim-A által aktivált acilcsoportok"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Acetil-koenzim-A" title="Acetil-koenzim-A">acetil-CoA</a></li> <li><a href="/w/index.php?title=Propionil-CoA&action=edit&redlink=1" class="new" title="Propionil-CoA (a lap nem létezik)">propionil-CoA</a></li> <li><a href="/w/index.php?title=Acetoacetil-CoA&action=edit&redlink=1" class="new" title="Acetoacetil-CoA (a lap nem létezik)">acetoacetil-CoA</a></li> <li><a href="/w/index.php?title=Kumaroil-CoA&action=edit&redlink=1" class="new" title="Kumaroil-CoA (a lap nem létezik)">kumaroil-CoA</a> (<a href="/wiki/Flavonoidok" title="Flavonoidok">flavonoid</a> és <a href="/w/index.php?title=Sztilbenoid&action=edit&redlink=1" class="new" title="Sztilbenoid (a lap nem létezik)">sztilbenoid</a> bioszintézis)</li> <li>dikrarbonsavak acilszármazékai <ul><li><a href="/w/index.php?title=Malonil-CoA&action=edit&redlink=1" class="new" title="Malonil-CoA (a lap nem létezik)">malonil-CoA</a></li> <li><a href="/wiki/Szukcinil-koenzim-A" title="Szukcinil-koenzim-A">szukcinil-CoA</a></li> <li><a href="/w/index.php?title=Hidroximetilglutaril-CoA&action=edit&redlink=1" class="new" title="Hidroximetilglutaril-CoA (a lap nem létezik)">hidroximetilglutaril-CoA</a> (izoprének bioszintézise)</li> <li><a href="/w/index.php?title=Pimelil-CoA&action=edit&redlink=1" class="new" title="Pimelil-CoA (a lap nem létezik)">pimelil-CoA</a> (<a href="/wiki/Biotin" title="Biotin">biotin</a> bioszitézise)</li></ul></li></ul> <div class="mw-heading mw-heading2"><h2 id="Szerkezet">Szerkezet</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Koenzim-A&action=edit&section=4" title="Szakasz szerkesztése: Szerkezet"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure typeof="mw:File/Thumb"><a href="/wiki/F%C3%A1jl:Coenzym_A_beschriftet.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/4/47/Coenzym_A_beschriftet.svg/500px-Coenzym_A_beschriftet.svg.png" decoding="async" width="500" height="203" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/47/Coenzym_A_beschriftet.svg/750px-Coenzym_A_beschriftet.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/47/Coenzym_A_beschriftet.svg/1000px-Coenzym_A_beschriftet.svg.png 2x" data-file-width="845" data-file-height="343" /></a><figcaption>A koenzim-A szerkezete</figcaption></figure> <p>Ciszteaminból (<b>5</b>), <a href="/w/index.php?title=B%C3%A9ta-alanin&action=edit&redlink=1" class="new" title="Béta-alanin (a lap nem létezik)">β-alaninból</a> (<b>4</b>), <a href="/w/index.php?title=Patoinsav&action=edit&redlink=1" class="new" title="Patoinsav (a lap nem létezik)">pantoinsavból</a> (<b>3</b>) és egy 3′-foszforilált <a href="/wiki/Adenozin-difoszf%C3%A1t" title="Adenozin-difoszfát">adenozin-difoszfát</a> (ADP; <b>1+2</b>) <a href="/wiki/Molekula" title="Molekula">molekula</a>részből épül fel, ahol a foszfát a ribózrész 3-as szénatomjához kapcsolódik. A β-alanin és a pantoinsav együtt alkotják a pantoténsavat (B5-vitamin), amely a ciszteaminnal panteteint képez. A CoA tehát 3-foszfo-ADP-ből és panteteinből tevődik össze. </p><p>A molekula (<b>5</b>) végén látható -SH-csoport neve szulfhidril- vagy <a href="/wiki/Tiolok" title="Tiolok">tiolcsoport</a>, aminek a párja a kevésbé reaktív, <a href="/wiki/Oxig%C3%A9n" title="Oxigén">oxigén</a> tartalmú alkoholos <a href="/wiki/Hidroxilcsoport" title="Hidroxilcsoport">hidroxilcsoport</a>. Az enzimatikus működés során a ciszteaminrész ezen tiolcsoportjához kötődnek a szállítandó acilcsoportok, tioésztereket képezve. </p> <div class="mw-heading mw-heading2"><h2 id="Források"><span id="Forr.C3.A1sok"></span>Források</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Koenzim-A&action=edit&section=5" title="Szakasz szerkesztése: Források"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>Karl Miller (1998). <a rel="nofollow" class="external text" href="https://web.archive.org/20100619135847/www.gwu.edu/~mpb/betaox.htm">Beta Oxidation of Fatty Acids</a>. Elérés: 2005. május 18.</li> <li>Charles Ophard (2003). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20071221033717/http://www.elmhurst.edu/~chm/vchembook/623acetylCoAfate.html">Acetyl-CoA Crossroads</a>. Elérés: 2005. május 18.</li> <li>Lehninger: Principles of Biochemistry, 4th edition, David L. Nelson, Michael M. Cox</li></ul> <div class="tarsprojekt-alap noviewer"> <style data-mw-deduplicate="TemplateStyles:r27252708">.mw-parser-output .tarsprojekt-alap{float:right;clear:right;width:272px;display:flex;column-gap:10px;margin:0 0 1em 1em;border:1px solid #a2a9b1;padding:4px;background-color:var(--background-color-neutral-subtle,#f8f9fa);color:var(--color-base,#202122);font-size:95%}@media screen and (max-width:719px){.mw-parser-output .tarsprojekt-alap{float:none;width:auto;margin:0 0 1em}}@media print{.mw-parser-output .tarsprojekt-alap{display:none}}</style> <div class="tarsprojekt-alap-ikon"><span typeof="mw:File"><a href="https://commons.wikimedia.org/wiki/Category:Coenzyme_A" title="commons:Category:Coenzyme A"><img alt="Commons:Category:Coenzyme A" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/50px-Commons-logo.svg.png" decoding="async" width="50" height="67" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/75px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/100px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span></div> <div class="tarsprojekt-alap-szoveg">A <a href="/wiki/Wikim%C3%A9dia_Commons" title="Wikimédia Commons">Wikimédia Commons</a> tartalmaz <i><b><a href="https://commons.wikimedia.org/wiki/Category:Coenzyme_A" class="extiw" title="commons:Category:Coenzyme A">Koenzim-A</a></b></i> témájú médiaállományokat.</div> </div> <table class="wikitable" style="clear: both;"> <tbody><tr> <th style="text-align: center; background-color: #ccccff;">A <a href="/wiki/Citromsavciklus" title="Citromsavciklus">citromsavciklus</a> anyagcsere-útvonala </th></tr> <tr> <td> <table style="border-collapse: collapse; text-align: center; font-size: 75%;"> <tbody><tr> <td rowspan="3"> </td> <td style="border: 1px solid #808080; border-bottom: none;"><a href="/wiki/Ox%C3%A1lecetsav" title="Oxálecetsav">oxálacetát</a> </td> <td colspan="2"> </td> <td style="border: 1px solid #808080; border-bottom: none;"><a href="/wiki/Almasav" title="Almasav">malát</a> </td> <td colspan="2"> </td> <td style="border: 1px solid #808080; border-bottom: none;"><a href="/wiki/Fum%C3%A1rsav" title="Fumársav">fumarát</a> </td> <td colspan="2"> </td> <td style="border: 1px solid #808080; border-bottom: none;"><a href="/wiki/Borosty%C3%A1nk%C5%91sav" title="Borostyánkősav">szukcinát</a> </td> <td colspan="2"> </td> <td style="border: 1px solid #808080; border-bottom: none;"><a href="/wiki/Szukcinil-koenzim-A" title="Szukcinil-koenzim-A">szukcinil-CoA</a> </td> <td rowspan="3"> </td></tr> <tr> <td rowspan="2" style="border: 1px solid #808080; border-top: none;"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Oxalacetat.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b2/Oxalacetat.svg/50px-Oxalacetat.svg.png" decoding="async" width="50" height="18" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b2/Oxalacetat.svg/75px-Oxalacetat.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b2/Oxalacetat.svg/100px-Oxalacetat.svg.png 2x" data-file-width="209" data-file-height="77" /></a></span> </td> <td colspan="2"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg/35px-Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg.png" decoding="async" width="35" height="35" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg/53px-Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/de/Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg/70px-Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg.png 2x" data-file-width="75" data-file-height="75" /></a></span> </td> <td rowspan="2" style="border: 1px solid #808080; border-top: none;"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:L-Malat.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/2/21/L-Malat.svg/50px-L-Malat.svg.png" decoding="async" width="50" height="18" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/21/L-Malat.svg/75px-L-Malat.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/21/L-Malat.svg/100px-L-Malat.svg.png 2x" data-file-width="211" data-file-height="77" /></a></span> </td> <td colspan="2"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Biochem_reaction_arrow_reverse_NNYN_horiz_med.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fa/Biochem_reaction_arrow_reverse_NNYN_horiz_med.svg/35px-Biochem_reaction_arrow_reverse_NNYN_horiz_med.svg.png" decoding="async" width="35" height="35" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fa/Biochem_reaction_arrow_reverse_NNYN_horiz_med.svg/53px-Biochem_reaction_arrow_reverse_NNYN_horiz_med.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fa/Biochem_reaction_arrow_reverse_NNYN_horiz_med.svg/70px-Biochem_reaction_arrow_reverse_NNYN_horiz_med.svg.png 2x" data-file-width="75" data-file-height="75" /></a></span> </td> <td rowspan="2" style="border: 1px solid #808080; border-top: none;"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Fumarat.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c1/Fumarat.svg/50px-Fumarat.svg.png" decoding="async" width="50" height="9" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c1/Fumarat.svg/75px-Fumarat.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c1/Fumarat.svg/100px-Fumarat.svg.png 2x" data-file-width="211" data-file-height="40" /></a></span> </td> <td colspan="2"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg/35px-Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg.png" decoding="async" width="35" height="35" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg/53px-Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/de/Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg/70px-Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg.png 2x" data-file-width="75" data-file-height="75" /></a></span> </td> <td rowspan="2" style="border: 1px solid #808080; border-top: none;"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Succinat.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f3/Succinat.svg/50px-Succinat.svg.png" decoding="async" width="50" height="9" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f3/Succinat.svg/75px-Succinat.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f3/Succinat.svg/100px-Succinat.svg.png 2x" data-file-width="211" data-file-height="40" /></a></span> </td> <td colspan="2"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg/35px-Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg.png" decoding="async" width="35" height="35" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg/53px-Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/de/Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg/70px-Biochem_reaction_arrow_reverse_NNYY_horiz_med.svg.png 2x" data-file-width="75" data-file-height="75" /></a></span> </td> <td rowspan="2" style="border: 1px solid #808080; border-top: none;"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Succinyl-CoA.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Succinyl-CoA.svg/50px-Succinyl-CoA.svg.png" decoding="async" width="50" height="15" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Succinyl-CoA.svg/75px-Succinyl-CoA.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Succinyl-CoA.svg/100px-Succinyl-CoA.svg.png 2x" data-file-width="263" data-file-height="79" /></a></span> </td></tr> <tr> <td valign="top"><a href="/wiki/Nikotinamid-adenin-dinukleotid" title="Nikotinamid-adenin-dinukleotid">NADH</a><b>+</b> H<sup>+</sup> </td> <td valign="top"><a href="/wiki/Nikotinamid-adenin-dinukleotid" title="Nikotinamid-adenin-dinukleotid">NAD<sup>+</sup></a> </td> <td valign="top"> </td> <td valign="top"><a href="/wiki/V%C3%ADz" title="Víz">H<sub>2</sub>O</a> </td> <td valign="top"><a href="/wiki/Q10" title="Q10">ubikinol</a> </td> <td valign="top"><a href="/wiki/Q10" title="Q10">ubikinon</a> </td> <td valign="top"><a class="mw-selflink selflink">CoA</a> <b>+</b><a href="/wiki/Adenozin-trifoszf%C3%A1t" title="Adenozin-trifoszfát">ATP</a><br />(<a href="/wiki/Guanozin-trifoszf%C3%A1t" title="Guanozin-trifoszfát">GTP</a>) </td> <td valign="top"><a href="/wiki/Foszforsav" title="Foszforsav">P<sub>i</sub></a> <b>+</b> <a href="/wiki/Adenozin-difoszf%C3%A1t" title="Adenozin-difoszfát">ADP</a><br />(<a href="/wiki/Guanozin-difoszf%C3%A1t" title="Guanozin-difoszfát">GDP</a>) </td></tr> <tr> <td align="right"> <table> <tbody><tr> <td><a href="/wiki/Acetil-koenzim-A" title="Acetil-koenzim-A">acetil-CoA</a> </td> <td colspan="2"> </td></tr> <tr> <td><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Acetyl-CoA.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/89/Acetyl-CoA.svg/50px-Acetyl-CoA.svg.png" decoding="async" width="50" height="23" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/89/Acetyl-CoA.svg/75px-Acetyl-CoA.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/89/Acetyl-CoA.svg/100px-Acetyl-CoA.svg.png 2x" data-file-width="176" data-file-height="82" /></a></span> </td> <td><b>+</b> </td> <td><a href="/wiki/V%C3%ADz" title="Víz">H<sub>2</sub>O</a> </td></tr></tbody></table> </td> <td rowspan="2"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Biochem_reaction_arrow_forward_YNNY_vert_med.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8f/Biochem_reaction_arrow_forward_YNNY_vert_med.svg/35px-Biochem_reaction_arrow_forward_YNNY_vert_med.svg.png" decoding="async" width="35" height="35" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8f/Biochem_reaction_arrow_forward_YNNY_vert_med.svg/53px-Biochem_reaction_arrow_forward_YNNY_vert_med.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8f/Biochem_reaction_arrow_forward_YNNY_vert_med.svg/70px-Biochem_reaction_arrow_forward_YNNY_vert_med.svg.png 2x" data-file-width="75" data-file-height="75" /></a></span> </td> <td colspan="11" rowspan="2"> </td> <td rowspan="2"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Biochem_reaction_arrow_reverse_NYYN_vert_med.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Biochem_reaction_arrow_reverse_NYYN_vert_med.svg/35px-Biochem_reaction_arrow_reverse_NYYN_vert_med.svg.png" decoding="async" width="35" height="35" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Biochem_reaction_arrow_reverse_NYYN_vert_med.svg/53px-Biochem_reaction_arrow_reverse_NYYN_vert_med.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Biochem_reaction_arrow_reverse_NYYN_vert_med.svg/70px-Biochem_reaction_arrow_reverse_NYYN_vert_med.svg.png 2x" data-file-width="75" data-file-height="75" /></a></span> </td> <td align="left"><a href="/wiki/Nikotinamid-adenin-dinukleotid" title="Nikotinamid-adenin-dinukleotid">NADH</a> <b>+</b> H<sup>+</sup> <b>+</b> <a href="/wiki/Sz%C3%A9n-dioxid" title="Szén-dioxid">CO<sub>2</sub></a> </td></tr> <tr> <td align="right" style="height: 4em;"><a class="mw-selflink selflink">CoA</a> </td> <td align="left"><a href="/wiki/Nikotinamid-adenin-dinukleotid" title="Nikotinamid-adenin-dinukleotid">NAD<sup>+</sup></a> </td></tr> <tr> <td rowspan="3"> </td> <td rowspan="2" style="border: 1px solid #808080; border-bottom: none;"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Citrat.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/4/40/Citrat.svg/50px-Citrat.svg.png" decoding="async" width="50" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/40/Citrat.svg/75px-Citrat.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/40/Citrat.svg/100px-Citrat.svg.png 2x" data-file-width="245" data-file-height="98" /></a></span> </td> <td valign="bottom"> </td> <td valign="bottom"><a href="/wiki/V%C3%ADz" title="Víz">H<sub>2</sub>O</a> </td> <td rowspan="2" style="border: 1px solid #808080; border-bottom: none;"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Cis-Aconitat.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Cis-Aconitat.svg/50px-Cis-Aconitat.svg.png" decoding="async" width="50" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Cis-Aconitat.svg/75px-Cis-Aconitat.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/6e/Cis-Aconitat.svg/100px-Cis-Aconitat.svg.png 2x" data-file-width="245" data-file-height="71" /></a></span> </td> <td valign="bottom"><a href="/wiki/V%C3%ADz" title="Víz">H<sub>2</sub>O</a> </td> <td valign="bottom"> </td> <td rowspan="2" style="border: 1px solid #808080; border-bottom: none;"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Isocitric_acid.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Isocitric_acid.svg/35px-Isocitric_acid.svg.png" decoding="async" width="35" height="47" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Isocitric_acid.svg/52px-Isocitric_acid.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e5/Isocitric_acid.svg/70px-Isocitric_acid.svg.png 2x" data-file-width="315" data-file-height="425" /></a></span> </td> <td valign="bottom"><a href="/wiki/Nikotinamid-adenin-dinukleotid" title="Nikotinamid-adenin-dinukleotid">NAD</a>(P)<sup>+</sup> </td> <td valign="bottom"><a href="/wiki/Nikotinamid-adenin-dinukleotid" title="Nikotinamid-adenin-dinukleotid">NAD</a>(P)H<br /><b>+</b> H<sup>+</sup> </td> <td rowspan="2" style="border: 1px solid #808080; border-bottom: none;"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Oxalsuccinat.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Oxalsuccinat.svg/50px-Oxalsuccinat.svg.png" decoding="async" width="50" height="24" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Oxalsuccinat.svg/75px-Oxalsuccinat.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d1/Oxalsuccinat.svg/100px-Oxalsuccinat.svg.png 2x" data-file-width="245" data-file-height="119" /></a></span> </td> <td valign="bottom"> </td> <td valign="bottom"><a href="/wiki/Sz%C3%A9n-dioxid" title="Szén-dioxid">CO<sub>2</sub></a> </td> <td rowspan="2" style="border: 1px solid #808080; border-bottom: none;"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:2-oxoglutarate_wpmp.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d9/2-oxoglutarate_wpmp.svg/24px-2-oxoglutarate_wpmp.svg.png" decoding="async" width="24" height="47" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d9/2-oxoglutarate_wpmp.svg/36px-2-oxoglutarate_wpmp.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d9/2-oxoglutarate_wpmp.svg/48px-2-oxoglutarate_wpmp.svg.png 2x" data-file-width="93" data-file-height="181" /></a></span> </td> <td rowspan="3"> </td></tr> <tr> <td colspan="2"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Biochem_reaction_arrow_forward_NYNN_horiz_med.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/09/Biochem_reaction_arrow_forward_NYNN_horiz_med.svg/35px-Biochem_reaction_arrow_forward_NYNN_horiz_med.svg.png" decoding="async" width="35" height="35" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/09/Biochem_reaction_arrow_forward_NYNN_horiz_med.svg/53px-Biochem_reaction_arrow_forward_NYNN_horiz_med.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/09/Biochem_reaction_arrow_forward_NYNN_horiz_med.svg/70px-Biochem_reaction_arrow_forward_NYNN_horiz_med.svg.png 2x" data-file-width="75" data-file-height="75" /></a></span> </td> <td colspan="2"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Biochem_reaction_arrow_forward_YNNN_horiz_med.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/1/12/Biochem_reaction_arrow_forward_YNNN_horiz_med.svg/35px-Biochem_reaction_arrow_forward_YNNN_horiz_med.svg.png" decoding="async" width="35" height="35" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/12/Biochem_reaction_arrow_forward_YNNN_horiz_med.svg/53px-Biochem_reaction_arrow_forward_YNNN_horiz_med.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/12/Biochem_reaction_arrow_forward_YNNN_horiz_med.svg/70px-Biochem_reaction_arrow_forward_YNNN_horiz_med.svg.png 2x" data-file-width="75" data-file-height="75" /></a></span> </td> <td colspan="2"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Biochem_reaction_arrow_forward_YYNN_horiz_med.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/85/Biochem_reaction_arrow_forward_YYNN_horiz_med.svg/35px-Biochem_reaction_arrow_forward_YYNN_horiz_med.svg.png" decoding="async" width="35" height="35" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/85/Biochem_reaction_arrow_forward_YYNN_horiz_med.svg/53px-Biochem_reaction_arrow_forward_YYNN_horiz_med.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/85/Biochem_reaction_arrow_forward_YYNN_horiz_med.svg/70px-Biochem_reaction_arrow_forward_YYNN_horiz_med.svg.png 2x" data-file-width="75" data-file-height="75" /></a></span> </td> <td colspan="2"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Biochem_reaction_arrow_forward_NYNN_horiz_med.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/09/Biochem_reaction_arrow_forward_NYNN_horiz_med.svg/35px-Biochem_reaction_arrow_forward_NYNN_horiz_med.svg.png" decoding="async" width="35" height="35" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/09/Biochem_reaction_arrow_forward_NYNN_horiz_med.svg/53px-Biochem_reaction_arrow_forward_NYNN_horiz_med.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/09/Biochem_reaction_arrow_forward_NYNN_horiz_med.svg/70px-Biochem_reaction_arrow_forward_NYNN_horiz_med.svg.png 2x" data-file-width="75" data-file-height="75" /></a></span> </td></tr> <tr> <td style="border: 1px solid #808080; 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