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cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">个人工具</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="用户菜单" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=zh.wikipedia.org&uselang=zh"><span>资助维基百科</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:%E5%88%9B%E5%BB%BA%E8%B4%A6%E6%88%B7&returnto=Pfam" title="我们推荐您创建账号并登录，但这不是强制性的"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>创建账号</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:%E7%94%A8%E6%88%B7%E7%99%BB%E5%BD%95&returnto=Pfam" title="建议你登录，尽管并非必须。[o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>登录</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> 未登录编辑者的页面 <a href="/wiki/Help:%E6%96%B0%E6%89%8B%E5%85%A5%E9%97%A8" aria-label="了解有关编辑的更多信息"><span>了解详情</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Special:%E6%88%91%E7%9A%84%E8%B4%A1%E7%8C%AE" title="来自此IP地址的编辑列表[y]" accesskey="y"><span>贡献</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Special:%E6%88%91%E7%9A%84%E8%AE%A8%E8%AE%BA%E9%A1%B5" title="对于来自此IP地址编辑的讨论[n]" accesskey="n"><span>讨论</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="站点"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="目录" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">目录</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">移至侧栏</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">隐藏</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">序言</div> </a> </li> <li id="toc-特色" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#特色"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>特色</span> </div> </a> <ul id="toc-特色-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-參見" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#參見"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>參見</span> </div> </a> <ul id="toc-參見-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-參考文獻" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#參考文獻"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>參考文獻</span> </div> </a> <ul id="toc-參考文獻-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-外部連結" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#外部連結"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>外部連結</span> </div> </a> <ul id="toc-外部連結-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="目录" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="目录" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="开关目录" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">开关目录</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Pfam</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="前往另一种语言写成的文章。21种语言可用" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-21" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">21种语言</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%82%D8%A7%D8%B9%D8%AF%D8%A9_%D8%A8%D9%8A%D8%A7%D9%86%D8%A7%D8%AA_%D8%B9%D9%88%D8%A7%D8%A6%D9%84_%D8%A7%D9%84%D8%A8%D8%B1%D9%88%D8%AA%D9%8A%D9%86%D8%A7%D8%AA" title="قاعدة بيانات عوائل البروتينات – 阿拉伯语" lang="ar" hreflang="ar" data-title="قاعدة بيانات عوائل البروتينات" data-language-autonym="العربية" data-language-local-name="阿拉伯语" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Pfam" title="Pfam – 波斯尼亚语" lang="bs" hreflang="bs" data-title="Pfam" data-language-autonym="Bosanski" data-language-local-name="波斯尼亚语" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Pfam" title="Pfam – 加泰罗尼亚语" lang="ca" hreflang="ca" data-title="Pfam" data-language-autonym="Català" data-language-local-name="加泰罗尼亚语" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Pfam" title="Pfam – 德语" lang="de" hreflang="de" data-title="Pfam" data-language-autonym="Deutsch" data-language-local-name="德语" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Pfam" title="Pfam – 英语" lang="en" hreflang="en" data-title="Pfam" data-language-autonym="English" data-language-local-name="英语" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Pfam" title="Pfam – 西班牙语" lang="es" hreflang="es" data-title="Pfam" data-language-autonym="Español" data-language-local-name="西班牙语" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%BE%DB%8C%E2%80%8C%D9%81%D9%85" title="پی‌فم – 波斯语" lang="fa" hreflang="fa" data-title="پی‌فم" data-language-autonym="فارسی" data-language-local-name="波斯语" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Pfam" title="Pfam – 法语" lang="fr" hreflang="fr" data-title="Pfam" data-language-autonym="Français" data-language-local-name="法语" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Pfam" title="Pfam – 加利西亚语" lang="gl" hreflang="gl" data-title="Pfam" data-language-autonym="Galego" data-language-local-name="加利西亚语" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Pfam" title="Pfam – 匈牙利语" lang="hu" hreflang="hu" data-title="Pfam" data-language-autonym="Magyar" data-language-local-name="匈牙利语" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Pfam" title="Pfam – 意大利语" lang="it" hreflang="it" data-title="Pfam" data-language-autonym="Italiano" data-language-local-name="意大利语" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/Pfam%E3%83%87%E3%83%BC%E3%82%BF%E3%83%99%E3%83%BC%E3%82%B9" title="Pfamデータベース – 日语" lang="ja" hreflang="ja" data-title="Pfamデータベース" data-language-autonym="日本語" data-language-local-name="日语" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/Pfam" title="Pfam – 韩语" lang="ko" hreflang="ko" data-title="Pfam" data-language-autonym="한국어" data-language-local-name="韩语" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Pfam" title="Pfam – 马来语" lang="ms" hreflang="ms" data-title="Pfam" data-language-autonym="Bahasa Melayu" data-language-local-name="马来语" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Pfam" title="Pfam – 葡萄牙语" lang="pt" hreflang="pt" data-title="Pfam" data-language-autonym="Português" data-language-local-name="葡萄牙语" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Pfam" title="Pfam – 罗马尼亚语" lang="ro" hreflang="ro" data-title="Pfam" data-language-autonym="Română" data-language-local-name="罗马尼亚语" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru badge-Q17559452 badge-recommendedarticle mw-list-item" title="推荐条目"><a href="https://ru.wikipedia.org/wiki/Pfam" title="Pfam – 俄语" lang="ru" hreflang="ru" data-title="Pfam" data-language-autonym="Русский" data-language-local-name="俄语" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Pfam" title="Pfam – 塞尔维亚-克罗地亚语" lang="sh" hreflang="sh" data-title="Pfam" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="塞尔维亚-克罗地亚语" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Pfam" title="Pfam – 塞尔维亚语" lang="sr" hreflang="sr" data-title="Pfam" data-language-autonym="Српски / srpski" data-language-local-name="塞尔维亚语" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Pfam" title="Pfam – 土耳其语" lang="tr" hreflang="tr" data-title="Pfam" data-language-autonym="Türkçe" data-language-local-name="土耳其语" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/Pfam" title="Pfam – 乌克兰语" lang="uk" hreflang="uk" data-title="Pfam" data-language-autonym="Українська" data-language-local-name="乌克兰语" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q906796#sitelinks-wikipedia" title="编辑跨语言链接" class="wbc-editpage">编辑链接</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="命名空间"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Pfam" title="浏览条目正文[c]" accesskey="c"><span>条目</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Talk:Pfam" rel="discussion" title="关于此页面的讨论[t]" accesskey="t"><span>讨论</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown " > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="更改语言变体" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">不转换</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-varlang-0" class="selected ca-variants-zh mw-list-item"><a href="/zh/Pfam" lang="zh" hreflang="zh"><span>不转换</span></a></li><li id="ca-varlang-1" class="ca-variants-zh-Hans mw-list-item"><a href="/zh-hans/Pfam" lang="zh-Hans" hreflang="zh-Hans"><span>简体</span></a></li><li id="ca-varlang-2" class="ca-variants-zh-Hant mw-list-item"><a href="/zh-hant/Pfam" lang="zh-Hant" hreflang="zh-Hant"><span>繁體</span></a></li><li id="ca-varlang-3" class="ca-variants-zh-Hans-CN mw-list-item"><a href="/zh-cn/Pfam" lang="zh-Hans-CN" hreflang="zh-Hans-CN"><span>大陆简体</span></a></li><li id="ca-varlang-4" class="ca-variants-zh-Hant-HK mw-list-item"><a href="/zh-hk/Pfam" lang="zh-Hant-HK" hreflang="zh-Hant-HK"><span>香港繁體</span></a></li><li id="ca-varlang-5" class="ca-variants-zh-Hant-MO mw-list-item"><a href="/zh-mo/Pfam" lang="zh-Hant-MO" hreflang="zh-Hant-MO"><span>澳門繁體</span></a></li><li id="ca-varlang-6" class="ca-variants-zh-Hans-MY mw-list-item"><a href="/zh-my/Pfam" lang="zh-Hans-MY" hreflang="zh-Hans-MY"><span>大马简体</span></a></li><li id="ca-varlang-7" class="ca-variants-zh-Hans-SG mw-list-item"><a href="/zh-sg/Pfam" lang="zh-Hans-SG" hreflang="zh-Hans-SG"><span>新加坡简体</span></a></li><li id="ca-varlang-8" class="ca-variants-zh-Hant-TW mw-list-item"><a href="/zh-tw/Pfam" lang="zh-Hant-TW" hreflang="zh-Hant-TW"><span>臺灣正體</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="查看"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Pfam"><span>阅读</span></a></li><li id="ca-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Pfam&action=edit" title="编辑该页面[e]" accesskey="e"><span>编辑</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Pfam&action=history" title="本页面的早前版本。[h]" accesskey="h"><span>查看历史</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="页面工具"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="工具" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">工具</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">工具</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">移至侧栏</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">隐藏</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="更多选项" > <div class="vector-menu-heading"> 操作 </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Pfam"><span>阅读</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Pfam&action=edit" title="编辑该页面[e]" accesskey="e"><span>编辑</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Pfam&action=history"><span>查看历史</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> 常规 </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Special:%E9%93%BE%E5%85%A5%E9%A1%B5%E9%9D%A2/Pfam" title="列出所有与本页相链的页面[j]" accesskey="j"><span>链入页面</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Special:%E9%93%BE%E5%87%BA%E6%9B%B4%E6%94%B9/Pfam" rel="nofollow" title="页面链出所有页面的更改[k]" accesskey="k"><span>相关更改</span></a></li><li id="t-upload" class="mw-list-item"><a href="//zh.wikipedia.org/wiki/Project:上传" title="上传图像或多媒体文件[u]" accesskey="u"><span>上传文件</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Pfam&oldid=80031658" title="此页面该修订版本的固定链接"><span>固定链接</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Pfam&action=info" title="关于此页面的更多信息"><span>页面信息</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Special:%E5%BC%95%E7%94%A8%E6%AD%A4%E9%A1%B5%E9%9D%A2&page=Pfam&id=80031658&wpFormIdentifier=titleform" title="有关如何引用此页面的信息"><span>引用此页</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Special:URL%E7%BC%A9%E7%9F%AD%E7%A8%8B%E5%BA%8F&url=https%3A%2F%2Fzh.wikipedia.org%2Fwiki%2FPfam"><span>获取短链接</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Special:QrCode&url=https%3A%2F%2Fzh.wikipedia.org%2Fwiki%2FPfam"><span>下载二维码</span></a></li> </ul> </div> </div> <div id="p-electronpdfservice-sidebar-portlet-heading" class="vector-menu mw-portlet mw-portlet-electronpdfservice-sidebar-portlet-heading" > <div class="vector-menu-heading"> 打印/导出 </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="electron-print_pdf" class="mw-list-item"><a href="/w/index.php?title=Special:DownloadAsPdf&page=Pfam&action=show-download-screen"><span>下载为PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="javascript:print();" rel="alternate" title="本页面的可打印版本[p]" accesskey="p"><span>打印页面</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> 在其他项目中 </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q906796" title="链接到连接的数据仓库项目[g]" accesskey="g"><span>维基数据项目</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="页面工具"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="外观"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">外观</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">移至侧栏</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">隐藏</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">维基百科，自由的百科全书</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="zh" dir="ltr"><style data-mw-deduplicate="TemplateStyles:r83732082">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}body.skin-minerva .mw-parser-output .infobox-header,body.skin-minerva .mw-parser-output .infobox-subheader,body.skin-minerva .mw-parser-output .infobox-above,body.skin-minerva .mw-parser-output .infobox-title,body.skin-minerva .mw-parser-output .infobox-image,body.skin-minerva .mw-parser-output .infobox-full-data,body.skin-minerva .mw-parser-output .infobox-below{text-align:center}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}html.skin-theme-clientpref-night .mw-parser-output .infobox td div:not(.notheme)[style]{background:transparent!important;color:var(--color-base,#202122)}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox td div:not(.notheme)[style]{background:transparent!important;color:var(--color-base,#202122)}}html.skin-theme-clientpref-night .mw-parser-output .infobox td div.NavHead:not(.notheme)[style]{background:transparent!important}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox td div.NavHead:not(.notheme)[style]{background:transparent!important}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox vevent" style="width:300px;"><caption class="infobox-title summary">Pfam</caption><tbody><tr><th colspan="2" class="infobox-above"><span typeof="mw:File"><a href="/wiki/File:Pfam_logo.gif" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/03/Pfam_logo.gif/120px-Pfam_logo.gif" decoding="async" width="120" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/03/Pfam_logo.gif/250px-Pfam_logo.gif 1.5x" data-file-width="720" data-file-height="240" /></a></span></th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ccf;">内容</th></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;"><a href="/wiki/%E7%94%9F%E7%89%A9" title="生物">有機體</a></th><td class="infobox-data" style="">全部</td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ccf;">相關信息</th></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;"><a href="/wiki/%E7%A0%94%E7%A9%B6%E4%B8%AD%E5%BF%83" class="mw-redirect" title="研究中心">研究中心</a></th><td class="infobox-data" style=""><span class="ilh-all" data-orig-title="Wellcome Trust Sanger Institute" data-lang-code="en" data-lang-name="英语" data-foreign-title="Wellcome Trust Sanger Institute"><span class="ilh-page"><a href="/w/index.php?title=Wellcome_Trust_Sanger_Institute&action=edit&redlink=1" class="new" title="Wellcome Trust Sanger Institute（页面不存在）">WTSI</a></span><span class="noprint ilh-comment"><span class="ilh-paren">（</span><span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Wellcome_Trust_Sanger_Institute" class="extiw" title="en:Wellcome Trust Sanger Institute"><span lang="en" dir="auto">Wellcome Trust Sanger Institute</span></a></span><span class="ilh-paren">）</span></span></span></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ccf;">访问入口</th></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;"><a href="/wiki/%E6%AA%94%E6%A1%88%E6%A0%BC%E5%BC%8F" title="檔案格式">数据格式</a></th><td class="infobox-data" style=""><span class="ilh-all" data-orig-title="Stockholm format" data-lang-code="en" data-lang-name="英语" data-foreign-title="Stockholm format"><span class="ilh-page"><a href="/w/index.php?title=Stockholm_format&action=edit&redlink=1" class="new" title="Stockholm format（页面不存在）">Stockholm format</a></span><span class="noprint ilh-comment"><span class="ilh-paren">（</span><span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Stockholm_format" class="extiw" title="en:Stockholm format"><span lang="en" dir="auto">Stockholm format</span></a></span><span class="ilh-paren">）</span></span></span></td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;">网站</th><td class="infobox-data" style=""><a rel="nofollow" class="external text" href="http://pfam.xfam.org/">Pfam</a></td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;">下載地址</th><td class="infobox-data" style=""><a rel="nofollow" class="external text" href="ftp://ftp.sanger.ac.uk/pub/databases/Pfam/">Pfam ftp</a><sup class="noprint Inline-Template"><span style="white-space: nowrap;">[<a href="/wiki/Wikipedia:%E5%A4%B1%E6%95%88%E9%93%BE%E6%8E%A5" title="Wikipedia:失效链接"><span title="自2017年11月失效">永久失效連結</span></a>]</span></sup> <a rel="nofollow" class="external text" href="ftp://ftp.ebi.ac.uk/pub/databases/Pfam">Pfam ftp</a></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ccf;">工具</th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ccf;">其他</th></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;"><a href="/wiki/%E8%BD%AF%E4%BB%B6%E8%AE%B8%E5%8F%AF%E8%AF%81" title="软件许可证">许可</a></th><td class="infobox-data" style=""><a href="/wiki/GNU%E5%AE%BD%E9%80%9A%E7%94%A8%E5%85%AC%E5%85%B1%E8%AE%B8%E5%8F%AF%E8%AF%81" title="GNU宽通用公共许可证">GNU宽通用公共许可证</a></td></tr><tr><th scope="row" class="infobox-label" style="white-space: nowrap;">可否列為書籤</th><td class="infobox-data" style="">yes</td></tr></tbody></table> <p><b>Pfam</b>是一個<a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B4%A8%E5%AE%B6%E6%97%8F" title="蛋白质家族">蛋白質家族</a>資料庫。此資料庫會利用<a href="/wiki/%E9%9A%B1%E9%A6%AC%E7%88%BE%E5%8F%AF%E5%A4%AB%E6%A8%A1%E5%9E%8B" class="mw-redirect" title="隱馬爾可夫模型">隱馬爾可夫模型</a>進行<a href="/wiki/%E5%A4%9A%E9%87%8D%E5%BA%8F%E5%88%97%E6%AF%94%E5%B0%8D" title="多重序列比對">多重序列比對</a>以及加上蛋白腳註<sup id="cite_ref-pmid18039703_1-0" class="reference"><a href="#cite_note-pmid18039703-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid16381856_2-0" class="reference"><a href="#cite_note-pmid16381856-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid14681378_3-0" class="reference"><a href="#cite_note-pmid14681378-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup>。 </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="特色"><span id=".E7.89.B9.E8.89.B2"></span>特色</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Pfam&action=edit&section=1" title="编辑章节：特色"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Pfam中所登錄的每一個蛋白質家族可以： </p> <ul><li>查詢多重序列比對</li> <li>查看蛋白質主要結構</li> <li>檢視物種演化樹</li> <li>連結其他資料庫</li> <li>查看已知的蛋白質結構</li></ul> <p>Pfam內的蛋白質家族描述由維基百科使用者管理。 </p><p>Pfam的最新版本是「Pfam 34.0」（2021年3月，共計19,179個家族）<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="參見"><span id=".E5.8F.83.E8.A6.8B"></span>參見</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Pfam&action=edit&section=2" title="编辑章节：參見"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/TrEMBL" class="mw-redirect" title="TrEMBL">TrEMBL</a> Database performing an automated protein sequence annotation</li> <li><span class="ilh-all" data-orig-title="InterPro" data-lang-code="en" data-lang-name="英语" data-foreign-title="InterPro"><span class="ilh-page"><a href="/w/index.php?title=InterPro&action=edit&redlink=1" class="new" title="InterPro（页面不存在）">InterPro</a></span><span class="noprint ilh-comment"><span class="ilh-paren">（</span><span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/InterPro" class="extiw" title="en:InterPro"><span lang="en" dir="auto">InterPro</span></a></span><span class="ilh-paren">）</span></span></span> Integration of protein domain and protein family databases</li> <li><a rel="nofollow" class="external text" href="http://dunbrack2.fccc.edu/protcid/pdbfam">PDBfam</a>（<a rel="nofollow" class="external text" href="//web.archive.org/web/20151001120514/http://dunbrack2.fccc.edu/protcid/pdbfam">页面存档备份</a>，存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>） — thorough assignment of Pfam domains to sequences in the <a href="/wiki/Protein_Data_Bank" class="mw-redirect" title="Protein Data Bank">Protein Data Bank</a> (PDB)<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup></li></ul> <div class="mw-heading mw-heading2"><h2 id="參考文獻"><span id=".E5.8F.83.E8.80.83.E6.96.87.E7.8D.BB"></span>參考文獻</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Pfam&action=edit&section=3" title="编辑章节：參考文獻"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist columns references-column-count references-column-count-2" style="-moz-column-count: 2; -webkit-column-count: 2; column-count: 2; list-style-type: decimal;"> <ol class="references"> <li id="cite_note-pmid18039703-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid18039703_1-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Finn RD, Tate J, Mistry J, Coggill PC, Sammut SJ, Hotz HR, Ceric G, Forslund K, Eddy SR, Sonnhammer EL, Bateman A. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2238907">The Pfam protein families database</a>. Nucleic Acids Res. 2008, <b>36</b> (Database issue): D281–8. <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2238907"><span title="公共医学中心">PMC 2238907</span></a> <span typeof="mw:File"><span title="可免费查阅"><img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18039703"><span title="公共医学识别码">PMID 18039703</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fnar%2Fgkm960"><span title="數位物件識別號">doi:10.1093/nar/gkm960</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3APfam&rft.atitle=The+Pfam+protein+families+database&rft.au=Finn+RD%2C+Tate+J%2C+Mistry+J%2C+Coggill+PC%2C+Sammut+SJ%2C+Hotz+HR%2C+Ceric+G%2C+Forslund+K%2C+Eddy+SR%2C+Sonnhammer+EL%2C+Bateman+A&rft.date=2008&rft.genre=article&rft.issue=Database+issue&rft.jtitle=Nucleic+Acids+Res&rft.pages=D281-8&rft.volume=36&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2238907&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2238907&rft_id=info%3Adoi%2F10.1093%2Fnar%2Fgkm960&rft_id=info%3Apmid%2F18039703&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid16381856-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid16381856_2-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Robert D. Finn, Jaina Mistry, Benjamin Schuster-Böckler, Sam Griffiths-Jones, Volker Hollich, Timo Lassmann, Simon Moxon, Mhairi Marshall, Ajay Khanna, Richard Durbin, Sean R. Eddy, Erik L. L. Sonnhammer, Alex Bateman. <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/16381856">Pfam: clans, web tools and services</a>. Nucleic Acids Research. 2006-01-01, <b>34</b> (Database issue): D247–251 <span class="reference-accessdate"> [<span class="nowrap">2019-02-12</span>]</span>. <a rel="nofollow" class="external text" href="//www.worldcat.org/issn/1362-4962"><span title="国际标准连续出版物号">ISSN 1362-4962</span></a>. <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1347511"><span title="公共医学中心">PMC 1347511</span></a> <span typeof="mw:File"><span title="可免费查阅"><img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16381856"><span title="公共医学识别码">PMID 16381856</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fnar%2Fgkj149"><span title="數位物件識別號">doi:10.1093/nar/gkj149</span></a>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20191016182044/https://www.ncbi.nlm.nih.gov/pubmed/16381856">存档</a>于2019-10-16）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3APfam&rft.atitle=Pfam%3A+clans%2C+web+tools+and+services&rft.au=Robert+D.+Finn%2C+Jaina+Mistry%2C+Benjamin+Schuster-B%C3%B6ckler%2C+Sam+Griffiths-Jones%2C+Volker+Hollich%2C+Timo+Lassmann%2C+Simon+Moxon%2C+Mhairi+Marshall%2C+Ajay+Khanna%2C+Richard+Durbin%2C+Sean+R.+Eddy%2C+Erik+L.+L.+Sonnhammer%2C+Alex+Bateman&rft.date=2006-01-01&rft.genre=article&rft.issn=1362-4962&rft.issue=Database+issue&rft.jtitle=Nucleic+Acids+Research&rft.pages=D247-251&rft.volume=34&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1347511&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F16381856&rft_id=info%3Adoi%2F10.1093%2Fnar%2Fgkj149&rft_id=info%3Apmid%2F16381856&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid14681378-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid14681378_3-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Alex Bateman, Lachlan Coin, Richard Durbin, Robert D. Finn, Volker Hollich, Sam Griffiths-Jones, Ajay Khanna, Mhairi Marshall, Simon Moxon, Erik L. L. Sonnhammer, David J. Studholme, Corin Yeats, Sean R. Eddy. <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/14681378">The Pfam protein families database</a>. Nucleic Acids Research. 2004-01-01, <b>32</b> (Database issue): D138–141 <span class="reference-accessdate"> [<span class="nowrap">2019-02-12</span>]</span>. <a rel="nofollow" class="external text" href="//www.worldcat.org/issn/1362-4962"><span title="国际标准连续出版物号">ISSN 1362-4962</span></a>. <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC308855"><span title="公共医学中心">PMC 308855</span></a> <span typeof="mw:File"><span title="可免费查阅"><img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/14681378"><span title="公共医学识别码">PMID 14681378</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fnar%2Fgkh121"><span title="數位物件識別號">doi:10.1093/nar/gkh121</span></a>. （原始内容<a rel="nofollow" class="external text" href="https://web.archive.org/web/20190328152232/https://www.ncbi.nlm.nih.gov/pubmed/14681378">存档</a>于2019-03-28）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3APfam&rft.atitle=The+Pfam+protein+families+database&rft.au=Alex+Bateman%2C+Lachlan+Coin%2C+Richard+Durbin%2C+Robert+D.+Finn%2C+Volker+Hollich%2C+Sam+Griffiths-Jones%2C+Ajay+Khanna%2C+Mhairi+Marshall%2C+Simon+Moxon%2C+Erik+L.+L.+Sonnhammer%2C+David+J.+Studholme%2C+Corin+Yeats%2C+Sean+R.+Eddy&rft.date=2004-01-01&rft.genre=article&rft.issn=1362-4962&rft.issue=Database+issue&rft.jtitle=Nucleic+Acids+Research&rft.pages=D138-141&rft.volume=32&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC308855&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmed%2F14681378&rft_id=info%3Adoi%2F10.1093%2Fnar%2Fgkh121&rft_id=info%3Apmid%2F14681378&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="ftp://ftp.sanger.ac.uk/pub/databases/Pfam/current_release/relnotes.txt">Pfam release notes</a>. Sanger. <span class="reference-accessdate"> [<span class="nowrap">2012-01-12</span>]</span>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3APfam&rft.btitle=Pfam+release+notes&rft.genre=unknown&rft.pub=Sanger&rft_id=ftp%3A%2F%2Fftp.sanger.ac.uk%2Fpub%2Fdatabases%2FPfam%2Fcurrent_release%2Frelnotes.txt&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span><sup class="noprint Inline-Template"><span style="white-space: nowrap;">[<a href="/wiki/Wikipedia:%E5%A4%B1%E6%95%88%E9%93%BE%E6%8E%A5" title="Wikipedia:失效链接"><span title="自2017年11月失效">永久失效連結</span></a>]</span></sup></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><cite class="citation web">Dunbrack, Roland. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20151001120514/http://dunbrack2.fccc.edu/protcid/pdbfam/">PDBfam</a>. PDBfam. Fox Chase Cancer Center. <span class="reference-accessdate"> [<span class="nowrap">9 March</span> 2013]</span>. （<a rel="nofollow" class="external text" href="http://dunbrack2.fccc.edu/protcid/pdbfam/">原始内容</a>存档于2015-10-01）.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3APfam&rft.atitle=PDBfam&rft.aufirst=Roland&rft.aulast=Dunbrack&rft.genre=unknown&rft.jtitle=PDBfam&rft_id=http%3A%2F%2Fdunbrack2.fccc.edu%2Fprotcid%2Fpdbfam%2F&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><cite class="citation journal">Xu, Qifang; Dunbrack, Roland. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3476341">Assignment of protein sequences to existing domain and family classification systems: Pfam and the PDB</a>. Bioinformatics. 2012, <b>28</b> (21): 2763–72. <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3476341"><span title="公共医学中心">PMC 3476341</span></a> <span typeof="mw:File"><span title="可免费查阅"><img alt="可免费查阅" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/22942020"><span title="公共医学识别码">PMID 22942020</span></a>. <a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fbioinformatics%2Fbts533"><span title="數位物件識別號">doi:10.1093/bioinformatics/bts533</span></a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3APfam&rft.atitle=Assignment+of+protein+sequences+to+existing+domain+and+family+classification+systems%3A+Pfam+and+the+PDB&rft.au=Dunbrack%2C+Roland&rft.aufirst=Qifang&rft.aulast=Xu&rft.date=2012&rft.genre=article&rft.issue=21&rft.jtitle=Bioinformatics&rft.pages=2763-72&rft.volume=28&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3476341&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3476341&rft_id=info%3Adoi%2F10.1093%2Fbioinformatics%2Fbts533&rft_id=info%3Apmid%2F22942020&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="外部連結"><span id=".E5.A4.96.E9.83.A8.E9.80.A3.E7.B5.90"></span>外部連結</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Pfam&action=edit&section=4" title="编辑章节：外部連結"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20140420020108/http://pfam.sanger.ac.uk/">Pfam</a> －<a href="/wiki/%E8%8B%B1%E5%9C%8B" class="mw-redirect" title="英國">英國</a><span class="ilh-all" data-orig-title="Sanger Institute" data-lang-code="en" data-lang-name="英语" data-foreign-title="Sanger Institute"><span class="ilh-page"><a href="/w/index.php?title=Sanger_Institute&action=edit&redlink=1" class="new" title="Sanger Institute（页面不存在）">Sanger Institute</a></span><span class="noprint ilh-comment"><span class="ilh-paren">（</span><span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Sanger_Institute" class="extiw" title="en:Sanger Institute"><span lang="en" dir="auto">Sanger Institute</span></a></span><span 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data-lang-code="en" data-lang-name="英语" data-foreign-title="Stockholm Bioinformatics Centre"><span class="ilh-page"><a href="/w/index.php?title=Stockholm_Bioinformatics_Centre&action=edit&redlink=1" class="new" title="Stockholm Bioinformatics Centre（页面不存在）">Stockholm Bioinformatics Centre</a></span><span class="noprint ilh-comment"><span class="ilh-paren">（</span><span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Stockholm_Bioinformatics_Centre" class="extiw" title="en:Stockholm Bioinformatics Centre"><span lang="en" dir="auto">Stockholm Bioinformatics Centre</span></a></span><span class="ilh-paren">）</span></span></span>的蛋白質家族資料庫</li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20110107193546/http://www.sanger.ac.uk/Software/Pfam/iPfam/">iPfam</a> - Interactions of Pfam domains in PDB</li> <li><a rel="nofollow" class="external text" href="http://dunbrack2.fccc.edu/protcid/pdbfam/">PDBfam</a>（<a rel="nofollow" class="external text" href="//web.archive.org/web/20151001120514/http://dunbrack2.fccc.edu/protcid/pdbfam/">页面存档备份</a>，存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>） - Assignments of Pfam domains to sequences in the PDB at <span class="ilh-all" data-orig-title="Fox Chase Cancer Center" data-lang-code="en" data-lang-name="英语" data-foreign-title="Fox Chase Cancer Center"><span class="ilh-page"><a href="/w/index.php?title=Fox_Chase_Cancer_Center&action=edit&redlink=1" class="new" title="Fox Chase Cancer Center（页面不存在）">Fox Chase Cancer Center</a></span><span class="noprint ilh-comment"><span class="ilh-paren">（</span><span class="ilh-lang">英语</span><span class="ilh-colon">：</span><span class="ilh-link"><a href="https://en.wikipedia.org/wiki/Fox_Chase_Cancer_Center" class="extiw" title="en:Fox Chase Cancer Center"><span lang="en" dir="auto">Fox Chase Cancer 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