PBS-Mini-.05 Bioreactors

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src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/6706ea0d79b85690c9bd7e31_pbs-mini-.05-image.png" loading="lazy" alt="PBS-0.1-Mini Vertical Wheel Bioreactors" class="responsive"/></div><div class="product-detail-wrapper"><h1 class="product-title-header">PBS-0.5 Mini Vertical-Wheel Bioreactor</h1><p>The PBS-0.5 Mini single use bioreactor is compatible with 300mL– 500mL working sample volumes and the best starting point for optimizing cell therapies by leveraging the benefits of vertical-wheel mixing that can be easily scaled up for larger sample volumes. </p><ul role="list" class="product-benefits-list"><li>Removable caps on single-use vessels allow for sterile liquid handling in biosafety hood</li><li>Product contact materials meet regulatory requirements for first-in-human clinical trials</li><li>Universal base unit is compatible with single-use vessels</li></ul><a id="mini-01-shop-button" href="https://shoppbsbiotech.com/collections/pbs-mini" target="_blank" class="mg-button mg-button-spacer w-button">Request a Quote</a></div><div class="mg-clear"></div></div></div></div><div class="section-resources"><div class="page-padding"><div class="conference-container"><h1 class="product-title-header product-resources-title">PBS-0.5 Mini Vertical-Wheel Resources</h1><div data-current="FAQ" data-easing="ease" data-duration-in="300" data-duration-out="100" class="product-tab-container w-tabs"><div class="w-tab-menu"><a data-w-tab="Part Numbers" id="pbs--05-part-numbers" class="product-tab-link w-inline-block w-tab-link"><div>Part Numbers</div></a><a data-w-tab="Specifications" id="pbs-05-specifications" class="product-tab-link w-inline-block w-tab-link"><div>Specifications</div></a><a data-w-tab="Application Notes" id="pbs-05-app-notes" class="product-tab-link w-inline-block w-tab-link"><div>Application Notes</div></a><a data-w-tab="FAQ" id="pbs-05-faqs" class="product-tab-link w-inline-block w-tab-link w--current"><div>FAQ</div></a><a data-w-tab="Manuals" id="pbs-05-manuals" class="product-tab-link w-inline-block w-tab-link"><div>Manuals</div></a></div><div class="w-tab-content"><div data-w-tab="Part Numbers" class="w-tab-pane"><div class="w-embed"><style> #mini-pbs-05-product { font-family: Karla; /* border: none; */ width: 100%; } td{ font-family: Karla; font-size: 16px; font-weight: 700; line-height: 24px; letter-spacing: 0px; text-align: left; } #mini-pbs-05-product td, #mini-pbs-05-product th { /* border: 1px solid #ddd; */ padding: 8px; } #mini-pbs-05-product th { padding-top: 13px; padding-bottom: 12px; text-align: center; background-color: #233B5C; color: white; border: 1px solid #C8CCD8; border-left: none; } table, th, td { border: 1px solid #C8CCD8; border-collapse: collapse; } td { border: 1px solid #C8CCD8; } #mini-pbs-01-product td { background-color: White; } </style> <table style="margin-top:1.25rem;" id="mini-pbs-05-product" cellspacing="0"> <tbody><tr> <th>Product Type</th> <th>Product</th> <th>Product Number</th> </tr> <tr> <td class="base" rowspan="1">Base Unit</td> <td><a target="_blank" href="https://shoppbsbiotech.com/account/register">PBS-Mini Vertical-Wheel Bioreactor Base Unit (120-240 V)</a></td> <td><a target="_blank" href="https://shoppbsbiotech.com/account/register">FA-UNI-B-501</a> </td> </tr> <tr> <td class="bags" rowspan="2">Single-Use Vessels</td> <td><a target="_blank" href="https://shoppbsbiotech.com/account/register">PBS-0.5 Vertical-Wheel Single-Use Vessel with Bottom Port (pack of 1)</a> </td> <td><a target="_blank" href="https://shoppbsbiotech.com/account/register">FA-0.5-D-101</a></td> </tr> <tr> <td> <a target="_blank" href="https://shoppbsbiotech.com/account/register">PBS-0.5 Vertical-Wheel Single-Use Vessel (pack of 4)</a> </td> <td> <a target="_blank" href="https://shoppbsbiotech.com/account/register">FA-0.5-D-001</a></td> </tr> <tr> <td class="base" rowspan="1">Accessories</td> <td><a target="_blank" href="https://shoppbsbiotech.com/account/register">PBS-Mini Extended 4-Gang DC Power Distribution Cable</a> </td> <td><a target="_blank" href="https://shoppbsbiotech.com/account/register">IA-UNI-BA-112</a></td> </tr> </tbody></table></div></div><div data-w-tab="Specifications" class="w-tab-pane"><div class="w-embed"><style> #mini-specifications-pbs-05 { font-family: Karla; /* border: none; */ width: 100%; } td{ font-family: Karla; font-size: 16px; font-weight: 700; line-height: 24px; letter-spacing: 0px; text-align: left; } #mini-specifications-pbs-05 td, #mini-specifications-pbs-05 th { /* border: 1px solid #ddd; */ padding: 8px; } #mini-specifications-pbs-05 th { padding-top: 13px; padding-bottom: 12px; text-align: center; background-color: #233B5C; color: white; border: 1px solid #C8CCD8; border-left: none; } table, th, td { border: 1px solid #C8CCD8; border-collapse: collapse; } td { border: 1px solid #C8CCD8; } #mini-specifications-pbs-05 td { background-color: White; } #mini-specifications-pbs-05 td.header-label { padding-top: .75rem; padding-bottom: .75rem; text-align: center; background-color: #233B5C; color: white; border: 1px solid #C8CCD8; border-left: none; width:20% } #mini-specifications-pbs-05 td.details-label { padding-left:1rem; } </style> <table style="margin-top:`1.25rem;" id="mini-specifications-pbs-05" cellspacing="0"> <tbody> <tr> <td class="header-label"> Working volume range:</td> <td class="details-label">100 - 500 mL (For liquid mixing) <br/>300 - 500 mL (For cell culture)</td> </tr> <tr> <td class="header-label">Number of ports</td> <td class="details-label"> 2</td> </tr> <tr> <td class="header-label"> Gassing </td> <td class="details-label">Diffusion through 0.22 micron filter on vent cap</td> </tr> <tr> <td class="header-label">iquid transfer</td> <td class="details-label">Port with screw-on vent cap</td> </tr> <tr> <td class="header-label">Product contact materials</td> <td class="details-label">Meet requirements for USP Class VI Testing for Plastics and/or ISO 10993 </td> </tr> </tbody></table></div><a id="mini-05-spec-button" href="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/66fd94ca16056b6217f9b874_pbs_01_mini_tech_spec.pdf" target="_blank" class="mg-button mg-button-spacer w-button">Download Full Technical Spec Sheet</a></div><div data-w-tab="Application Notes" class="w-tab-pane"><div class="w-embed"><style> #mini-app-notes { font-family: Karla; /* border: none; */ width: 100%; } td{ font-family: Karla; font-size: 16px; font-weight: 700; line-height: 24px; letter-spacing: 0px; text-align: left; } #mini-app-notes td, #mini-app-notes th { /* border: 1px solid #ddd; */ padding: 8px; } #mini-app-notes th { padding-top: 13px; padding-bottom: 12px; text-align: center; background-color: #233B5C; color: white; border: 1px solid #C8CCD8; border-left: none; } table, th, td { border: 1px solid #C8CCD8; border-collapse: collapse; } td { border: 1px solid #C8CCD8; } #mini-app-notes{ background-color: White; } .product-app-note-button:link,.product-app-note-button:visited { float: right; clear: both; background-color: #f77c00; margin-left: 0; padding-left: 10px; padding-right: 10px; display: inline-block; color: #fff; border-color: #f77c00; border-radius: 3px; transition: all .2s linear; /* display: block; */ padding-top: 8px; padding-bottom: 8px; border: 1px solid #f77c00; } .product-app-note-button:hover { background-color: #fff; color:#f77c00; border: 1px solid #f77c00; } </style> <table style="margin-top:1.25rem;" id="mini-app-notes" cellspacing="0"> <tbody><tr> <th>Application Note Title</th> <th> </th> </tr> <tr> <td>Defined Biomatrices Accelerate MSC Manufacturing Across Scales</td> <td><a class="product-app-note-button" target="_blank" href="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/6434a6a639b63b4b7a7ac231_2023%20Defined%20Biomatrices%20Accelerate%20MSC%20Manufacturing%20Across%20Scales.pdf">Read Now</a></td> </tr> <tr> <td>T Cell Expansion in PBS-Mini Using CellGenix Reagents</td> <td><a class="product-app-note-button" target="_blank" href="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/63d42345104e46912d28bcb4_AppNote_CellGenix-TCM-in-PBS-Mini-Bioreactor.pdf">Read Now</a> </td> </tr> <tr> <td>Overcoming Bioprocess Bottlenecks in the Large-Scale Expansion of High-Quality hiPSC Aggregates in Vertical-Wheel Stirred Suspension Bioreactors</td> <td> <a class="product-app-note-button" target="_blank" href="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/63b68833b19e11c7b880dca7_2021%20Borys%20et%20al.%20-%20Overcoming%20Bioprocess%20Bottlenecks%20in%20Large-Scale%20Expansion.pdf">Read Now</a> </td> </tr> <tr> <td>Transcriptome Profiling of Human Pluripotent Stem Cell-Derived Cerebellar Organoids Reveals Faster Commitment Under Dynamic Conditions</td> <td><a class="product-app-note-button" target="_blank" href="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/66f193cc69429dc834312438_transcriptome_profiling_psc-comprssd.pdf">Read More</a> </td> </tr> <tr> <td>Initial Power Measurements for a Family of Novel Bioreactors</td> <td><a class="product-app-note-button" target="_blank" href="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/63b684a592188ebf9a76f829_2022%20Croughan%20et%20al.%20-%20Initial%20Power%20Measurements%20for%20a%20Family%20of%20Novel%20Bioreactors.pdf">Read More</a> </td> </tr> </tbody></table></div></div><div data-w-tab="FAQ" class="w-tab-pane w--tab-active"><div class="w-embed w-script"><style> table#mini-5-faq{ font-family: Karla; /* border: none; */ width: 100%; } td{ font-family: Karla; font-size: 16px; font-weight: 700; line-height: 24px; letter-spacing: 0px; text-align: left; } #mmini-5-faq td, #mini-5-faq th { border:nine!important; padding: 8px; } #mini-5-faq th { padding-top: 13px; padding-bottom: 12px; text-align: center; 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padding-top:1rem; } .question-answer-wrapper { position:relative; } img.question-one-icon, img.question-two-icon, img.question-three-icon, img.question-four-icon, img.question-five-icon { display:block; cursor:pointer; position: absolute; top:30%; left:50%; transform: translate(-50%, -90%) rotate(180deg); } img.answer-one-icon, img.answer-two-icon, img.answer-three-icon, img.answer-four-icon, img.answer-five-icon { display: none; cursor: pointer; position: absolute; top: 15%; left: 50%; transform: translate(-50%, -10%) rotate(0deg); } </style> <div style="max-width:800px; margin:0 auto"> <table style="margin-top:1.25rem;" id="mini-5-faq" cellspacing="0"> <tr> <td class="question-answer-detail-wrapper"><p class="question question-one">How can I monitor process parameters during a cell culture run?</p> <p class="answer answer-one">The 3L bioreactor's software allows for customizable programming of process controls and real-time monitoring of parameters using various sensors. Feedback loops can be used to pause a run based on deviations from a set range.</p></td> <td class="question-answer-icon-wrapper"> <img class="question-one-icon" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe730298c484ee4_faq-icon.svg"/> <img class="answer-one-icon" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe730298c484ee4_faq-icon.svg"/> </td> </tr> <tr> <td class="question-answer-detail-wrapper"><p class="question question-two">What are recommended methods for sampling and harvesting?</p> <p class="answer answer-two">Both sampling and harvesting of cells can be achieved by unscrewing the orange cap on top of the single-use vessel (one cap on 0.1L, two caps on 0.5L vessel) and using a pipette to withdraw media. It is recommended to perform these procedures under a biosafety hood.</p></td> <td class="question-answer-icon-wrapper"> <img class="question-two-icon" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe730298c484ee4_faq-icon.svg"/> <img class="answer-two-icon" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe730298c484ee4_faq-icon.svg"/> </td> </tr> <tr> <td class="question-answer-detail-wrapper"><p class="question question-three">What is the function of the power accessory cable?</p> <p class="answer answer-three">This accessory allows the power cables from four different Mini bases to be combined into one plug for a wall outlet.</p></td> <td class="question-answer-icon-wrapper"> <img class="question-three-icon" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe730298c484ee4_faq-icon.svg"/> <img class="answer-three-icon" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe730298c484ee4_faq-icon.svg"/> </td> </tr> <tr> <td class="question-answer-detail-wrapper"><p class="question question-four">What if I have other questions regarding usage or troubleshooting?</p> <p class="answer answer-four">Please use the Products and/or Service quote form to submit any questions or inquiries related to a specific product(s).</p></td> <td class="question-answer-icon-wrapper"> <img class="question-four-icon" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe730298c484ee4_faq-icon.svg"/> <img class="answer-four-icon" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe730298c484ee4_faq-icon.svg"/> </td> </tr> <tr> <td class="question-answer-detail-wrapper"><p class="question question-five">What data are available demonstrating the performance of Vertical-Wheel bioreactors?</p> <p class="answer answer-five">Our Publications section lists numerous examples of cell culture performance data for various cell types generated by customers and collaborators as well as by our BioLab team.</p></td> <td class="question-answer-icon-wrapper"> <img class="question-five-icon" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe730298c484ee4_faq-icon.svg"/> <img class="answer-five-icon" src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe730298c484ee4_faq-icon.svg"/> </td> </tr> </tbody></table> </div> <script src="https://ajax.googleapis.com/ajax/libs/jquery/3.7.1/jquery.min.js"></script> <script> //question 1 $(function(){ $(".question-one-icon").click(function(){ $(".question-one-icon").hide(function(){ $(".answer-one,.answer-one-icon").show("fast") }) }); 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} .product-app-note-button:link,.product-app-note-button:visited { float: right; clear: both; -webkit-text-stroke-color: var(--button-primary); background-color: #f77c00; margin-left: 0; padding-left: 5px; padding-right: 5px; display: inline-block; color:#fff; border-color: #f77c00; bordeer-radius:5px; transition: all .2s linear; } .product-app-note-button:hover { background-color: #fff; color:#f77c00; } </style> <table style="margin-top:1.25rem;" id="mini-manual" cellspacing="0"> <tbody><tr> <th>Title</th> <th> </th> </tr> <tr> <td>PBS-Mini User Manual</td> <td><a class="product-app-note-button" target="_blank" href="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/637d599d4e51f9249cc99fca_IC03504%20Rev%20B%20(Digital).pdf">Read Now</a></td> </tr> <tr> <td>PBS-Mini Datasheet</td> <td><a class="product-app-note-button" target="_blank" href="https://cdn.prod.website-files.com/62cc627d7fe730df74484ebd/63c9e3e59ae7592dee18bd73_PBS%20Mini%20Datasheet%20IC03422%20Rev%20B%20(Digital).pdf">Read Now</a> </td> </tr> </tbody></table></div></div></div></div></div></div></div><div class="section-service-card"><div class="page-padding"><div class="conference-container"><div class="feature-card-container"><div class="feature-card-wrapper"><div class="feature-card-image"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/6706b19e61223266dc3e459d_pbs-mini-feature-card-image.png" loading="lazy" sizes="300px" srcset="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/6706b19e61223266dc3e459d_pbs-mini-feature-card-image-p-500.png 500w, https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/6706b19e61223266dc3e459d_pbs-mini-feature-card-image.png 651w" alt="PBS-Mini Single-use bioreactor in the lab" class="responsive"/></div><div class="feature-card-detail"><h2 class="feature-card-title"> Need Help Maximizing the Yield and Quality of Your Cells?</h2><p class="featured-card-text">We can help! Our team of scientists and engineers are well-versed in developing cell culture procedures for various types of therapeutic cells using the PBS-0.5 Mini single use bioreactor. We can help with:</p><ul role="list" class="featured-card-list"><li>Cell separation, washing, and concentration</li><li>Rapid medium exchange techniques</li><li>Aggregate-based processes including seeding, expansion, differentiation, dissociation, and harvesting</li></ul><div class="featured-button-wrapper"><a id="mini-01-service-button" href="https://www.pbsbiotech.com/services#request-block" class="mg-button w-button">Request Support Now</a></div></div></div></div></div></div></div></div><footer class="footer-component"><div class="page-padding"><div class="footer-container"><div class="footer-content-wrapper mg-footer-content-wrapper"><div class="footer-left-wrapper"><a href="/" class="footer-logo-wrapper w-inline-block"><img src="https://cdn.prod.website-files.com/62cc627d7fe73059b1484e97/62cc627d7fe7301598484edc_footer-logo.svg" loading="lazy" alt="footer logo" class="footer-logo"/></a><div class="footer-address-wrapper"><div class="footer-text-link">PBS Biotech, Inc.<br/>4721 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