CINXE.COM

<!doctype html> <html lang="en-US"> <head> <meta charset="UTF-8"> <meta name="viewport" content="width=device-width, initial-scale=1"> <link rel="profile" href="https://gmpg.org/xfn/11"> <meta name='robots' content='index, follow, max-image-preview:large, max-snippet:-1, max-video-preview:-1' /> <style>img:is([sizes="auto" i], [sizes^="auto," i]) { contain-intrinsic-size: 3000px 1500px }</style> <script id="cookieyes" type="text/javascript" src="https://cdn-cookieyes.com/client_data/c92f49e1ac9a9239c874cd4c/script.js"></script>  <title>News/Events & Publications - Nerviano Medical Sciences</title><link rel="preload" data-rocket-preload as="style" href="https://fonts.googleapis.com/css?family=Work%20Sans%3A100%2C100italic%2C200%2C200italic%2C300%2C300italic%2C400%2C400italic%2C500%2C500italic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic%2C900%2C900italic&display=swap" /><link rel="stylesheet" href="https://fonts.googleapis.com/css?family=Work%20Sans%3A100%2C100italic%2C200%2C200italic%2C300%2C300italic%2C400%2C400italic%2C500%2C500italic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic%2C900%2C900italic&display=swap" media="print" onload="this.media='all'" /><noscript><link rel="stylesheet" href="https://fonts.googleapis.com/css?family=Work%20Sans%3A100%2C100italic%2C200%2C200italic%2C300%2C300italic%2C400%2C400italic%2C500%2C500italic%2C600%2C600italic%2C700%2C700italic%2C800%2C800italic%2C900%2C900italic&display=swap" /></noscript><link rel="preload" data-rocket-preload as="image" href="https://www.nervianoms.com/wp-content/uploads/2024/10/banner-inner-1.jpg" fetchpriority="high"> <link rel="canonical" href="https://www.nervianoms.com/news-events-publications/" /> <meta property="og:locale" content="en_US" /> <meta property="og:type" content="article" /> <meta property="og:title" content="News/Events & Publications - Nerviano Medical Sciences" /> <meta property="og:description" content="News Events Publications Expand All 2024 Integrative ensemble modelling of cetuximab sensitivity in colorectal cancer patient-derived xenografts Perron U, Grassi E, Chatzipli A, Viviani M, Karakoc E, Trastulla L, Brochier LM, Isella C, Zanella ER, Klett H, Molineris I, Schueler J, Esteller M, Medico E, Conte N, McDermott U, Trusolino L, Bertotti A, Iorio F […]" /> <meta property="og:url" content="https://www.nervianoms.com/news-events-publications/" /> <meta property="og:site_name" content="Nerviano Medical Sciences" /> <meta property="article:modified_time" content="2025-01-29T07:13:41+00:00" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:label1" content="Est. reading time" /> <meta name="twitter:data1" content="26 minutes" /> <script type="application/ld+json" class="yoast-schema-graph">{"@context":"https://schema.org","@graph":[{"@type":"WebPage","@id":"https://www.nervianoms.com/news-events-publications/","url":"https://www.nervianoms.com/news-events-publications/","name":"News/Events & Publications - Nerviano Medical Sciences","isPartOf":{"@id":"https://www.nervianoms.com/#website"},"datePublished":"2024-10-07T07:09:50+00:00","dateModified":"2025-01-29T07:13:41+00:00","breadcrumb":{"@id":"https://www.nervianoms.com/news-events-publications/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https://www.nervianoms.com/news-events-publications/"]}]},{"@type":"BreadcrumbList","@id":"https://www.nervianoms.com/news-events-publications/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.nervianoms.com/"},{"@type":"ListItem","position":2,"name":"News/Events & Publications"}]},{"@type":"WebSite","@id":"https://www.nervianoms.com/#website","url":"https://www.nervianoms.com/","name":"Nerviano Medical Sciences","description":"Clinical Development of New Chemical Entities","publisher":{"@id":"https://www.nervianoms.com/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://www.nervianoms.com/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https://www.nervianoms.com/#organization","name":"Nerviano Medical Sciences","url":"https://www.nervianoms.com/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https://www.nervianoms.com/#/schema/logo/image/","url":"https://www.nervianoms.com/wp-content/uploads/2024/10/nerviano-logo.png","contentUrl":"https://www.nervianoms.com/wp-content/uploads/2024/10/nerviano-logo.png","width":2053,"height":860,"caption":"Nerviano Medical Sciences"},"image":{"@id":"https://www.nervianoms.com/#/schema/logo/image/"}}]}</script>  <link href='https://fonts.gstatic.com' crossorigin rel='preconnect' /> <link rel="alternate" type="application/rss+xml" title="Nerviano Medical Sciences » Feed" href="https://www.nervianoms.com/feed/" /> <link rel="alternate" type="application/rss+xml" title="Nerviano Medical Sciences » Comments Feed" href="https://www.nervianoms.com/comments/feed/" /> <link rel='stylesheet' id='hello-elementor-theme-style-css' href='https://www.nervianoms.com/wp-content/themes/hello-elementor/theme.min.css?ver=3.2.1' media='all' /> <link rel='stylesheet' id='elementor-frontend-css' href='https://www.nervianoms.com/wp-content/uploads/elementor/css/custom-frontend.min.css?ver=1738135125' media='all' /> <link rel='stylesheet' id='eael-general-css' href='https://www.nervianoms.com/wp-content/plugins/essential-addons-for-elementor-lite/assets/front-end/css/view/general.min.css?ver=6.1.0' media='all' /> <link rel='stylesheet' id='eael-216-css' href='https://www.nervianoms.com/wp-content/uploads/essential-addons-elementor/eael-216.css?ver=1738116821' media='all' /> <style id='wp-emoji-styles-inline-css'> img.wp-smiley, img.emoji { display: inline !important; border: none !important; box-shadow: none !important; height: 1em !important; width: 1em !important; margin: 0 0.07em !important; vertical-align: -0.1em !important; background: none !important; padding: 0 !important; } </style> <style id='global-styles-inline-css'> :root{--wp--preset--aspect-ratio--square: 1;--wp--preset--aspect-ratio--4-3: 4/3;--wp--preset--aspect-ratio--3-4: 3/4;--wp--preset--aspect-ratio--3-2: 3/2;--wp--preset--aspect-ratio--2-3: 2/3;--wp--preset--aspect-ratio--16-9: 16/9;--wp--preset--aspect-ratio--9-16: 9/16;--wp--preset--color--black: #000000;--wp--preset--color--cyan-bluish-gray: #abb8c3;--wp--preset--color--white: #ffffff;--wp--preset--color--pale-pink: #f78da7;--wp--preset--color--vivid-red: #cf2e2e;--wp--preset--color--luminous-vivid-orange: #ff6900;--wp--preset--color--luminous-vivid-amber: #fcb900;--wp--preset--color--light-green-cyan: #7bdcb5;--wp--preset--color--vivid-green-cyan: #00d084;--wp--preset--color--pale-cyan-blue: #8ed1fc;--wp--preset--color--vivid-cyan-blue: #0693e3;--wp--preset--color--vivid-purple: #9b51e0;--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple: linear-gradient(135deg,rgba(6,147,227,1) 0%,rgb(155,81,224) 100%);--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan: linear-gradient(135deg,rgb(122,220,180) 0%,rgb(0,208,130) 100%);--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange: linear-gradient(135deg,rgba(252,185,0,1) 0%,rgba(255,105,0,1) 100%);--wp--preset--gradient--luminous-vivid-orange-to-vivid-red: linear-gradient(135deg,rgba(255,105,0,1) 0%,rgb(207,46,46) 100%);--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray: linear-gradient(135deg,rgb(238,238,238) 0%,rgb(169,184,195) 100%);--wp--preset--gradient--cool-to-warm-spectrum: linear-gradient(135deg,rgb(74,234,220) 0%,rgb(151,120,209) 20%,rgb(207,42,186) 40%,rgb(238,44,130) 60%,rgb(251,105,98) 80%,rgb(254,248,76) 100%);--wp--preset--gradient--blush-light-purple: linear-gradient(135deg,rgb(255,206,236) 0%,rgb(152,150,240) 100%);--wp--preset--gradient--blush-bordeaux: linear-gradient(135deg,rgb(254,205,165) 0%,rgb(254,45,45) 50%,rgb(107,0,62) 100%);--wp--preset--gradient--luminous-dusk: linear-gradient(135deg,rgb(255,203,112) 0%,rgb(199,81,192) 50%,rgb(65,88,208) 100%);--wp--preset--gradient--pale-ocean: linear-gradient(135deg,rgb(255,245,203) 0%,rgb(182,227,212) 50%,rgb(51,167,181) 100%);--wp--preset--gradient--electric-grass: linear-gradient(135deg,rgb(202,248,128) 0%,rgb(113,206,126) 100%);--wp--preset--gradient--midnight: linear-gradient(135deg,rgb(2,3,129) 0%,rgb(40,116,252) 100%);--wp--preset--font-size--small: 13px;--wp--preset--font-size--medium: 20px;--wp--preset--font-size--large: 36px;--wp--preset--font-size--x-large: 42px;--wp--preset--spacing--20: 0.44rem;--wp--preset--spacing--30: 0.67rem;--wp--preset--spacing--40: 1rem;--wp--preset--spacing--50: 1.5rem;--wp--preset--spacing--60: 2.25rem;--wp--preset--spacing--70: 3.38rem;--wp--preset--spacing--80: 5.06rem;--wp--preset--shadow--natural: 6px 6px 9px rgba(0, 0, 0, 0.2);--wp--preset--shadow--deep: 12px 12px 50px rgba(0, 0, 0, 0.4);--wp--preset--shadow--sharp: 6px 6px 0px rgba(0, 0, 0, 0.2);--wp--preset--shadow--outlined: 6px 6px 0px -3px rgba(255, 255, 255, 1), 6px 6px rgba(0, 0, 0, 1);--wp--preset--shadow--crisp: 6px 6px 0px rgba(0, 0, 0, 1);}:root { --wp--style--global--content-size: 800px;--wp--style--global--wide-size: 1200px; }:where(body) { margin: 0; }.wp-site-blocks > .alignleft { float: left; margin-right: 2em; }.wp-site-blocks > .alignright { float: right; margin-left: 2em; }.wp-site-blocks > .aligncenter { justify-content: center; margin-left: auto; margin-right: auto; }:where(.wp-site-blocks) > * { margin-block-start: 24px; margin-block-end: 0; }:where(.wp-site-blocks) > :first-child { margin-block-start: 0; }:where(.wp-site-blocks) > :last-child { margin-block-end: 0; }:root { --wp--style--block-gap: 24px; }:root :where(.is-layout-flow) > :first-child{margin-block-start: 0;}:root :where(.is-layout-flow) > :last-child{margin-block-end: 0;}:root :where(.is-layout-flow) > *{margin-block-start: 24px;margin-block-end: 0;}:root :where(.is-layout-constrained) > :first-child{margin-block-start: 0;}:root :where(.is-layout-constrained) > :last-child{margin-block-end: 0;}:root :where(.is-layout-constrained) > *{margin-block-start: 24px;margin-block-end: 0;}:root :where(.is-layout-flex){gap: 24px;}:root :where(.is-layout-grid){gap: 24px;}.is-layout-flow > .alignleft{float: left;margin-inline-start: 0;margin-inline-end: 2em;}.is-layout-flow > .alignright{float: right;margin-inline-start: 2em;margin-inline-end: 0;}.is-layout-flow > .aligncenter{margin-left: auto !important;margin-right: auto !important;}.is-layout-constrained > .alignleft{float: left;margin-inline-start: 0;margin-inline-end: 2em;}.is-layout-constrained > .alignright{float: right;margin-inline-start: 2em;margin-inline-end: 0;}.is-layout-constrained > .aligncenter{margin-left: auto !important;margin-right: auto !important;}.is-layout-constrained > :where(:not(.alignleft):not(.alignright):not(.alignfull)){max-width: var(--wp--style--global--content-size);margin-left: auto !important;margin-right: auto !important;}.is-layout-constrained > .alignwide{max-width: var(--wp--style--global--wide-size);}body .is-layout-flex{display: flex;}.is-layout-flex{flex-wrap: wrap;align-items: center;}.is-layout-flex > :is(*, div){margin: 0;}body .is-layout-grid{display: grid;}.is-layout-grid > :is(*, div){margin: 0;}body{padding-top: 0px;padding-right: 0px;padding-bottom: 0px;padding-left: 0px;}a:where(:not(.wp-element-button)){text-decoration: underline;}:root :where(.wp-element-button, .wp-block-button__link){background-color: #32373c;border-width: 0;color: #fff;font-family: inherit;font-size: inherit;line-height: inherit;padding: calc(0.667em + 2px) calc(1.333em + 2px);text-decoration: none;}.has-black-color{color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-color{color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-color{color: var(--wp--preset--color--white) !important;}.has-pale-pink-color{color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-color{color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-color{color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-color{color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-color{color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-color{color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-color{color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-color{color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-color{color: var(--wp--preset--color--vivid-purple) !important;}.has-black-background-color{background-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-background-color{background-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-background-color{background-color: var(--wp--preset--color--white) !important;}.has-pale-pink-background-color{background-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-background-color{background-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-background-color{background-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-background-color{background-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-background-color{background-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-background-color{background-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-background-color{background-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-background-color{background-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-background-color{background-color: var(--wp--preset--color--vivid-purple) !important;}.has-black-border-color{border-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-border-color{border-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-border-color{border-color: var(--wp--preset--color--white) !important;}.has-pale-pink-border-color{border-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-border-color{border-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-border-color{border-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-border-color{border-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-border-color{border-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-border-color{border-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-border-color{border-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-border-color{border-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-border-color{border-color: var(--wp--preset--color--vivid-purple) !important;}.has-vivid-cyan-blue-to-vivid-purple-gradient-background{background: var(--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple) !important;}.has-light-green-cyan-to-vivid-green-cyan-gradient-background{background: var(--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan) !important;}.has-luminous-vivid-amber-to-luminous-vivid-orange-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange) !important;}.has-luminous-vivid-orange-to-vivid-red-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-orange-to-vivid-red) !important;}.has-very-light-gray-to-cyan-bluish-gray-gradient-background{background: var(--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray) !important;}.has-cool-to-warm-spectrum-gradient-background{background: var(--wp--preset--gradient--cool-to-warm-spectrum) !important;}.has-blush-light-purple-gradient-background{background: var(--wp--preset--gradient--blush-light-purple) !important;}.has-blush-bordeaux-gradient-background{background: var(--wp--preset--gradient--blush-bordeaux) !important;}.has-luminous-dusk-gradient-background{background: var(--wp--preset--gradient--luminous-dusk) !important;}.has-pale-ocean-gradient-background{background: var(--wp--preset--gradient--pale-ocean) !important;}.has-electric-grass-gradient-background{background: var(--wp--preset--gradient--electric-grass) !important;}.has-midnight-gradient-background{background: var(--wp--preset--gradient--midnight) !important;}.has-small-font-size{font-size: var(--wp--preset--font-size--small) !important;}.has-medium-font-size{font-size: var(--wp--preset--font-size--medium) !important;}.has-large-font-size{font-size: var(--wp--preset--font-size--large) !important;}.has-x-large-font-size{font-size: var(--wp--preset--font-size--x-large) !important;} :root :where(.wp-block-pullquote){font-size: 1.5em;line-height: 1.6;} </style> <link rel='stylesheet' id='hello-elementor-css' href='https://www.nervianoms.com/wp-content/themes/hello-elementor/style.min.css?ver=3.2.1' media='all' /> <link rel='stylesheet' id='hello-elementor-header-footer-css' href='https://www.nervianoms.com/wp-content/themes/hello-elementor/header-footer.min.css?ver=3.2.1' media='all' /> <link rel='stylesheet' id='elementor-post-7-css' href='https://www.nervianoms.com/wp-content/uploads/elementor/css/post-7.css?ver=1738135126' media='all' /> <link rel='stylesheet' id='widget-image-css' href='https://www.nervianoms.com/wp-content/plugins/elementor/assets/css/widget-image.min.css?ver=3.26.4' media='all' /> <link rel='stylesheet' id='widget-nav-menu-css' href='https://www.nervianoms.com/wp-content/uploads/elementor/css/custom-pro-widget-nav-menu.min.css?ver=1738135125' media='all' /> <link rel='stylesheet' id='widget-search-form-css' href='https://www.nervianoms.com/wp-content/plugins/elementor-pro/assets/css/widget-search-form.min.css?ver=3.26.3' media='all' /> <link rel='stylesheet' id='widget-heading-css' href='https://www.nervianoms.com/wp-content/plugins/elementor/assets/css/widget-heading.min.css?ver=3.26.4' media='all' /> <link rel='stylesheet' id='widget-breadcrumbs-css' href='https://www.nervianoms.com/wp-content/plugins/elementor-pro/assets/css/widget-breadcrumbs.min.css?ver=3.26.3' media='all' /> <link rel='stylesheet' id='widget-icon-box-css' href='https://www.nervianoms.com/wp-content/uploads/elementor/css/custom-widget-icon-box.min.css?ver=1738135125' media='all' /> <link rel='stylesheet' id='widget-text-editor-css' href='https://www.nervianoms.com/wp-content/plugins/elementor/assets/css/widget-text-editor.min.css?ver=3.26.4' media='all' /> <link rel='stylesheet' id='eael-42-css' href='https://www.nervianoms.com/wp-content/uploads/essential-addons-elementor/eael-42.css?ver=1738116821' media='all' /> <link rel='stylesheet' id='widget-loop-common-css' href='https://www.nervianoms.com/wp-content/plugins/elementor-pro/assets/css/widget-loop-common.min.css?ver=3.26.3' media='all' /> <link rel='stylesheet' id='widget-loop-grid-css' href='https://www.nervianoms.com/wp-content/uploads/elementor/css/custom-pro-widget-loop-grid.min.css?ver=1738135125' media='all' /> <link rel='stylesheet' id='widget-nested-accordion-css' href='https://www.nervianoms.com/wp-content/plugins/elementor/assets/css/widget-nested-accordion.min.css?ver=3.26.4' media='all' /> <link rel='stylesheet' id='elementor-post-42-css' href='https://www.nervianoms.com/wp-content/uploads/elementor/css/post-42.css?ver=1738135246' media='all' /> <link rel='stylesheet' id='elementor-post-468-css' href='https://www.nervianoms.com/wp-content/uploads/elementor/css/post-468.css?ver=1738135128' media='all' /> <link rel='stylesheet' id='elementor-post-216-css' href='https://www.nervianoms.com/wp-content/uploads/elementor/css/post-216.css?ver=1738135129' media='all' /> <link rel='stylesheet' id='hello-elementor-child-style-css' href='https://www.nervianoms.com/wp-content/themes/hello-theme-child-master/style.css?ver=2.0.0' media='all' /> <link rel="preconnect" href="https://fonts.gstatic.com/" crossorigin><script src="https://www.nervianoms.com/wp-includes/js/jquery/jquery.min.js?ver=3.7.1" id="jquery-core-js"></script> <script src="https://www.nervianoms.com/wp-includes/js/jquery/jquery-migrate.min.js?ver=3.4.1" id="jquery-migrate-js"></script> <link rel="https://api.w.org/" href="https://www.nervianoms.com/wp-json/" /><link rel="alternate" title="JSON" type="application/json" href="https://www.nervianoms.com/wp-json/wp/v2/pages/42" /><link rel="EditURI" type="application/rsd+xml" title="RSD" href="https://www.nervianoms.com/xmlrpc.php?rsd" /> <meta name="generator" content="WordPress 6.7.2" /> <link rel='shortlink' href='https://www.nervianoms.com/?p=42' /> <link rel="alternate" title="oEmbed (JSON)" type="application/json+oembed" href="https://www.nervianoms.com/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.nervianoms.com%2Fnews-events-publications%2F" /> <link rel="alternate" title="oEmbed (XML)" type="text/xml+oembed" href="https://www.nervianoms.com/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.nervianoms.com%2Fnews-events-publications%2F&format=xml" /> <meta name="generator" content="Elementor 3.26.4; features: e_font_icon_svg, additional_custom_breakpoints, e_element_cache; settings: css_print_method-external, google_font-enabled, font_display-swap"> <style> .e-con.e-parent:nth-of-type(n+4):not(.e-lazyloaded):not(.e-no-lazyload), .e-con.e-parent:nth-of-type(n+4):not(.e-lazyloaded):not(.e-no-lazyload) * { background-image: none !important; } @media screen and (max-height: 1024px) { .e-con.e-parent:nth-of-type(n+3):not(.e-lazyloaded):not(.e-no-lazyload), .e-con.e-parent:nth-of-type(n+3):not(.e-lazyloaded):not(.e-no-lazyload) * { background-image: none !important; } } @media screen and (max-height: 640px) { .e-con.e-parent:nth-of-type(n+2):not(.e-lazyloaded):not(.e-no-lazyload), .e-con.e-parent:nth-of-type(n+2):not(.e-lazyloaded):not(.e-no-lazyload) * { background-image: none !important; } } </style> <link rel="icon" href="https://www.nervianoms.com/wp-content/uploads/2024/10/cropped-fav-32x32.png" sizes="32x32" /> <link rel="icon" href="https://www.nervianoms.com/wp-content/uploads/2024/10/cropped-fav-192x192.png" sizes="192x192" /> <link rel="apple-touch-icon" href="https://www.nervianoms.com/wp-content/uploads/2024/10/cropped-fav-180x180.png" /> <meta name="msapplication-TileImage" content="https://www.nervianoms.com/wp-content/uploads/2024/10/cropped-fav-270x270.png" /> <style id="wp-custom-css"> div.wpcf7-validation-errors, .wpcf7 form.invalid .wpcf7-response-output, .wpcf7 form.unaccepted .wpcf7-response-output, .wpcf7 form.spam .wpcf7-response-output { border: 0; color: #dc3232; margin: 0 auto; font-weight: bold; text-align: left; width: 100%; float:left; margin-bottom:14px; font-size: 14px; background:none; padding:0.2em 0 } .wpcf7-not-valid-tip { color: #dc3232!important; font-size: 12px; background:none; } div.wpcf7-mail-sent-ok, .wpcf7 form.sent .wpcf7-response-output { border: 0; color: #35b302; margin: 0; font-weight: bold; text-align: left; width: 100%; font-size: 14px; float: left; margin-bottom: 10px; background:none; padding:0.2em 0 } .input-left {float:left; width:49%;} .input-right {float:right; width:49%;} .input-full {float:left; width:100%;} .ul-space ul {margin-bottom:20px;} .elementor-button-icon svg { width: 2em; height: auto; border-radius: 100%; } .share svg g {fill:#4b4b4b!important; stroke: #4b4b4b!important;} .elementor-button { line-height: 2.8rem; } h2.elementor-heading-title {position:relative; padding-left:15px;} h2.elementor-heading-title:before {content:""; position:absolute; left:0; top:4px; width:10px; height:100%; background: linear-gradient(0deg, #931b14 0%, #f8382d 100%);} .homestyle h1.elementor-heading-title {position:relative; padding-left:15px;font-size: 2.1rem!important; font-weight: 700!important;} .homestyle h1.elementor-heading-title:before {content:""; position:absolute; left:0; top:4px; width:10px; height:100%; background: linear-gradient(0deg, #931b14 0%, #f8382d 100%);} .news-inner-wrap-view {background:#fff; padding:20px;} .home .news-short-content {display:none;} .news .news-title { line-height: 1.5rem; min-height: 150px; } .news .news-title a{ font-size: 1.2rem; line-height: 1.2rem; } .news-more-link {background:none!important; padding:0!important} .footer-main .elementor-nav-menu li:first-child a {font-weight:700; color:#fff!important} .footer-main .bottom-menu .elementor-nav-menu li:first-child a {font-weight:400;} .instastions {font-size:.8rem!important} textarea {height:100px} input[type="submit"] {padding:6px 20px!important} .recaptcha { margin-bottom: 0 !important; display: block; } .show-more {color:var( --e-global-color-accent ) !important; cursor:pointer} .show-more2 {color:var( --e-global-color-accent ) !important; cursor:pointer} .show-more2:hover {color:#000!important} .wpcf7-acceptance span {margin:0!important; font-size:1rem} .wpcf7-acceptance input{ float: left; margin-bottom: 10px; margin-right: 10px; } .input-full p, .input-left p, .input-right p{margin-bottom:0!important} .input-left, .input-full, .input-right {margin-bottom:15px!important} .search-results .post { border-bottom: 1px solid #ccc; padding-bottom: 20px; margin-bottom: 25px; } .e-n-accordion-item ul {margin-left:0!important; padding-left:20px!important } .ul-formatting ul {margin-bottom:20px!important } .footer-links .elementor-nav-menu > li:after {border-radius:100%!important} .cells-left {position:relative;overflow:hidden} .cells-left:after {content:""; position:absolute; background:url(https://www.nervianoms.com/wp-content/uploads/2024/10/cell.png) no-repeat -10% center; background-size:cover; width:300px; height:300px; left:-170px; top:17%;} .cells-right {position:relative; overflow:hidden} .cells-right:after {content:""; position:absolute; background:url(https://www.nervianoms.com/wp-content/uploads/2024/10/cell.png) no-repeat -10% center; background-size:cover; width:300px; height:300px; right:-170px; bottom:-6%;} .cells-left2:after {top:2%} input[type="submit"] {color: var( --e-global-color-d7547b7 )!important; background: linear-gradient(99deg, #F75225 0%, #FF0000 100%)!important; border:none;; border-radius:30px!important; padding:7px 30px 7px 30px!important; font-size:1.2rem!important} input[type="submit"]:hover { background: linear-gradient(99deg, #FF0000 0%, #F75225 100%)!important;} .heading-anchor h3 a {color:var( --e-global-color-accent )!important} .heading-anchor h3 a:hover {color:var( --e-global-color-primary )!important} .text-wrap td{word-break:break-word; padding:5px; font-size:.8rem} .text-wrap th {padding:5px; font-size:.8rem} .elementor-nav-menu--dropdown a {border:none!important;} .ul-profile ul {margin-bottom:20px!important} .menu-sitemap .elementor-nav-menu--main .elementor-nav-menu ul { position: relative; width:100%!important; border-width: 0; border-style: solid; padding: 0; margin-left:0!important; position:relative!important; display:block!important } .menu-sitemap .elementor-nav-menu--main .elementor-nav-menu ul ul {margin-left:30px!important} .min-height-address {min-height:200px} #e-n-accordion-item-6613 {padding-left:35px;} #e-n-accordion-item-6614 {padding-left:35px;} button.cky-btn { font-size: .8rem; } @media only screen and (max-width: 1024px){ .e-con-inner {padding-left:30px!important; padding-right:30px!important;} .home .e-con-inner {padding-left:0!important; padding-right:0!important;} .input-left, .input-right {width:100%; } } @media only screen and (max-width:768px){ .footer-links .elementor-nav-menu>li { display: block; float: left; width: 100%; position:relative; } .footer-links .elementor-nav-menu>li a {margin-left:20px!important} .footer-links .elementor-nav-menu>li:after {position:absolute; content: var(--e-nav-menu-divider-content, none)!important; height: var(--e-nav-menu-divider-height, 35%)!important; border-left: var(--e-nav-menu-divider-width, 2px) var(--e-nav-menu-divider-style, solid) var(--e-nav-menu-divider-color, #000)!important; border-bottom-color: var(--e-nav-menu-divider-color, #000)!important; border-right-color: var(--e-nav-menu-divider-color, #000)!important; border-top-color: var(--e-nav-menu-divider-color, #000)!important; align-self: center!important; top:5px; } .table-adjustment td {float:left; width:100%} .more-btn .elementor-button {text-align:left!important} .wpcf7-recaptcha iframe{ transform:scale(0.77); -webkit-transform:scale(0.77); transform-origin:0 0; -webkit-transform-origin:0 0; } .cells-right:after, .cells-left:after {content:none!important} .elementor-nav-menu--toggle .elementor-menu-toggle.elementor-active + .elementor-nav-menu__container {top:0!important} .color-shift::before, .color-shift::after {content:none!important} } </style> <meta name="generator" content="WP Rocket 3.17.4" data-wpr-features="wpr_oci wpr_desktop wpr_preload_links" /></head> <body class="page-template-default page page-id-42 wp-custom-logo wp-embed-responsive elementor-default elementor-kit-7 elementor-page elementor-page-42"> <a class="skip-link screen-reader-text" href="#content">Skip to content</a> <div data-elementor-type="header" data-elementor-id="468" class="elementor elementor-468 elementor-location-header" data-elementor-post-type="elementor_library"> <div class="elementor-element elementor-element-7bd2098 e-flex e-con-boxed e-con e-parent" data-id="7bd2098" data-element_type="container"> <div class="e-con-inner"> <div class="elementor-element elementor-element-6ea5e49 e-con-full e-flex e-con e-child" data-id="6ea5e49" data-element_type="container"> <div class="elementor-element elementor-element-37c6818 elementor-widget elementor-widget-theme-site-logo elementor-widget-image" data-id="37c6818" data-element_type="widget" data-widget_type="theme-site-logo.default"> <div class="elementor-widget-container"> <a href="https://www.nervianoms.com"> <img width="2053" height="860" src="https://www.nervianoms.com/wp-content/uploads/2024/10/nerviano-logo.png" class="attachment-full size-full wp-image-10" alt="Nerviano Medical Sciences Logo" srcset="https://www.nervianoms.com/wp-content/uploads/2024/10/nerviano-logo.png 2053w, https://www.nervianoms.com/wp-content/uploads/2024/10/nerviano-logo-300x126.png 300w, https://www.nervianoms.com/wp-content/uploads/2024/10/nerviano-logo-1024x429.png 1024w, https://www.nervianoms.com/wp-content/uploads/2024/10/nerviano-logo-768x322.png 768w, https://www.nervianoms.com/wp-content/uploads/2024/10/nerviano-logo-1536x643.png 1536w, https://www.nervianoms.com/wp-content/uploads/2024/10/nerviano-logo-2048x858.png 2048w" sizes="(max-width: 2053px) 100vw, 2053px" /> </a> </div> </div> </div> <div class="elementor-element elementor-element-5474d57 e-con-full e-flex e-con e-child" data-id="5474d57" data-element_type="container"> <div class="elementor-element elementor-element-dc2a47f elementor-nav-menu__align-end elementor-widget__width-inherit elementor-nav-menu--stretch elementor-widget-mobile__width-auto elementor-nav-menu--dropdown-tablet elementor-nav-menu__text-align-aside elementor-nav-menu--toggle elementor-nav-menu--burger elementor-widget elementor-widget-nav-menu" data-id="dc2a47f" data-element_type="widget" data-settings="{"full_width":"stretch","layout":"horizontal","submenu_icon":{"value":"<svg class=\"e-font-icon-svg e-fas-caret-down\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\"><\/path><\/svg>","library":"fa-solid"},"toggle":"burger"}" data-widget_type="nav-menu.default"> <div class="elementor-widget-container"> <nav aria-label="Menu" class="elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-horizontal e--pointer-none"> <ul id="menu-1-dc2a47f" class="elementor-nav-menu"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-67"><a href="https://www.nervianoms.com/about-us/" class="elementor-item">About Us</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1391"><a href="/about-us/#history" class="elementor-sub-item elementor-item-anchor">History</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1396"><a href="/about-us/#leadership" class="elementor-sub-item elementor-item-anchor">Leadership</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1397"><a href="/about-us/#scientific-advisory-board" class="elementor-sub-item elementor-item-anchor">Scientific Advisory Board</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1401"><a href="/about-us/#collaboration-and-partnership" class="elementor-sub-item elementor-item-anchor">Collaboration and Partnership</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1402"><a href="/about-us/#locations" class="elementor-sub-item elementor-item-anchor">Locations</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-73"><a href="https://www.nervianoms.com/our-science/" class="elementor-item">Our Science</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1415"><a href="/our-science/#small-molecules" class="elementor-sub-item elementor-item-anchor">Small Molecules</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1414"><a href="/our-science/#adc-platform" class="elementor-sub-item elementor-item-anchor">ADC Platform</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-79"><a href="https://www.nervianoms.com/pipeline/" class="elementor-item">Pipeline</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-1610"><a href="https://www.nervianoms.com/our-science/#small-molecules" class="elementor-sub-item elementor-item-anchor">Small Molecules</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-4681"><a href="https://www.nervianoms.com/pipeline/" class="elementor-sub-item">Kinases</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1611"><a href="https://www.nervianoms.com/pipeline/#pipeline_encorafenib" class="elementor-sub-item elementor-item-anchor">Encorafenib (BRAF)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1612"><a href="https://www.nervianoms.com/pipeline/#pipeline_entrectinib" class="elementor-sub-item elementor-item-anchor">Entrectinib (TRK, ROS)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1613"><a href="https://www.nervianoms.com/pipeline/#pipeline_onvansertib" class="elementor-sub-item elementor-item-anchor">Onvansertib (PLK1)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1615"><a href="https://www.nervianoms.com/pipeline/#pipeline_NMS-153" class="elementor-sub-item elementor-item-anchor">NMS-153 (MPS1)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1616"><a href="https://www.nervianoms.com/pipeline/#pipeline_NMS-812" class="elementor-sub-item elementor-item-anchor">NMS-812 (PERK/ GCN2)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1617"><a href="https://www.nervianoms.com/pipeline/#early_pipeline" class="elementor-sub-item elementor-item-anchor">Early Pipeline Projects</a></li> </ul> </li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-4682"><a href="https://www.nervianoms.com/pipeline/#pipeline_NMS-293" class="elementor-sub-item elementor-item-anchor">NAD+ Binding Family: PARP</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1614"><a href="https://www.nervianoms.com/pipeline/#pipeline_NMS-293" class="elementor-sub-item elementor-item-anchor">NMS-293 (PARP1)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-4683"><a href="https://www.nervianoms.com/pipeline//pipeline/#pipeline_atamparib" class="elementor-sub-item elementor-item-anchor">Atamparib (PARP7)</a></li> </ul> </li> </ul> </li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-1618"><a href="https://www.nervianoms.com/our-science/#adc-platform" class="elementor-sub-item elementor-item-anchor">ADC Platform</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1619"><a href="https://www.nervianoms.com/pipeline/#pipeline_PDC" class="elementor-sub-item elementor-item-anchor">Peptide Drug Conjugate (PDC)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1620"><a href="https://www.nervianoms.com/pipeline/#pipeline_ADC" class="elementor-sub-item elementor-item-anchor">Antibody Drug Conjugate (ADC)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1621"><a href="https://www.nervianoms.com/pipeline/#pipeline_payload_linkers" class="elementor-sub-item elementor-item-anchor">Platform of Payload- Linkers</a></li> </ul> </li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page current-menu-item page_item page-item-42 current_page_item current-menu-ancestor current-menu-parent current_page_parent current_page_ancestor menu-item-has-children menu-item-4609"><a href="https://www.nervianoms.com/news-events-publications/" aria-current="page" class="elementor-item elementor-item-active">News/Events & Publications</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4610"><a href="https://www.nervianoms.com/news-events-publications//#news" aria-current="page" class="elementor-sub-item elementor-item-anchor">News</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4611"><a href="https://www.nervianoms.com/news-events-publications/#events" aria-current="page" class="elementor-sub-item elementor-item-anchor">Events</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4612"><a href="https://www.nervianoms.com/news-events-publications/#publications" aria-current="page" class="elementor-sub-item elementor-item-anchor">Publications</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-80"><a href="https://www.nervianoms.com/careers/" class="elementor-item">Careers</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-81"><a href="https://www.nervianoms.com/contact-us/" class="elementor-item">Contact Us</a></li> </ul> </nav> <div class="elementor-menu-toggle" role="button" tabindex="0" aria-label="Menu Toggle" aria-expanded="false"> <svg aria-hidden="true" role="presentation" class="elementor-menu-toggle__icon--open e-font-icon-svg e-eicon-menu-bar" viewBox="0 0 1000 1000" xmlns="http://www.w3.org/2000/svg"><path d="M104 333H896C929 333 958 304 958 271S929 208 896 208H104C71 208 42 237 42 271S71 333 104 333ZM104 583H896C929 583 958 554 958 521S929 458 896 458H104C71 458 42 487 42 521S71 583 104 583ZM104 833H896C929 833 958 804 958 771S929 708 896 708H104C71 708 42 737 42 771S71 833 104 833Z"></path></svg><svg aria-hidden="true" role="presentation" class="elementor-menu-toggle__icon--close e-font-icon-svg e-eicon-close" viewBox="0 0 1000 1000" xmlns="http://www.w3.org/2000/svg"><path d="M742 167L500 408 258 167C246 154 233 150 217 150 196 150 179 158 167 167 154 179 150 196 150 212 150 229 154 242 171 254L408 500 167 742C138 771 138 800 167 829 196 858 225 858 254 829L496 587 738 829C750 842 767 846 783 846 800 846 817 842 829 829 842 817 846 804 846 783 846 767 842 750 829 737L588 500 833 258C863 229 863 200 833 171 804 137 775 137 742 167Z"></path></svg> </div> <nav class="elementor-nav-menu--dropdown elementor-nav-menu__container" aria-hidden="true"> <ul id="menu-2-dc2a47f" class="elementor-nav-menu"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-67"><a href="https://www.nervianoms.com/about-us/" class="elementor-item" tabindex="-1">About Us</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1391"><a href="/about-us/#history" class="elementor-sub-item elementor-item-anchor" tabindex="-1">History</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1396"><a href="/about-us/#leadership" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Leadership</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1397"><a href="/about-us/#scientific-advisory-board" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Scientific Advisory Board</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1401"><a href="/about-us/#collaboration-and-partnership" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Collaboration and Partnership</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1402"><a href="/about-us/#locations" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Locations</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-73"><a href="https://www.nervianoms.com/our-science/" class="elementor-item" tabindex="-1">Our Science</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1415"><a href="/our-science/#small-molecules" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Small Molecules</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1414"><a href="/our-science/#adc-platform" class="elementor-sub-item elementor-item-anchor" tabindex="-1">ADC Platform</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-has-children menu-item-79"><a href="https://www.nervianoms.com/pipeline/" class="elementor-item" tabindex="-1">Pipeline</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-1610"><a href="https://www.nervianoms.com/our-science/#small-molecules" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Small Molecules</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-4681"><a href="https://www.nervianoms.com/pipeline/" class="elementor-sub-item" tabindex="-1">Kinases</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1611"><a href="https://www.nervianoms.com/pipeline/#pipeline_encorafenib" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Encorafenib (BRAF)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1612"><a href="https://www.nervianoms.com/pipeline/#pipeline_entrectinib" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Entrectinib (TRK, ROS)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1613"><a href="https://www.nervianoms.com/pipeline/#pipeline_onvansertib" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Onvansertib (PLK1)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1615"><a href="https://www.nervianoms.com/pipeline/#pipeline_NMS-153" class="elementor-sub-item elementor-item-anchor" tabindex="-1">NMS-153 (MPS1)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1616"><a href="https://www.nervianoms.com/pipeline/#pipeline_NMS-812" class="elementor-sub-item elementor-item-anchor" tabindex="-1">NMS-812 (PERK/ GCN2)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1617"><a href="https://www.nervianoms.com/pipeline/#early_pipeline" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Early Pipeline Projects</a></li> </ul> </li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-4682"><a href="https://www.nervianoms.com/pipeline/#pipeline_NMS-293" class="elementor-sub-item elementor-item-anchor" tabindex="-1">NAD+ Binding Family: PARP</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1614"><a href="https://www.nervianoms.com/pipeline/#pipeline_NMS-293" class="elementor-sub-item elementor-item-anchor" tabindex="-1">NMS-293 (PARP1)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-4683"><a href="https://www.nervianoms.com/pipeline//pipeline/#pipeline_atamparib" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Atamparib (PARP7)</a></li> </ul> </li> </ul> </li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-1618"><a href="https://www.nervianoms.com/our-science/#adc-platform" class="elementor-sub-item elementor-item-anchor" tabindex="-1">ADC Platform</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1619"><a href="https://www.nervianoms.com/pipeline/#pipeline_PDC" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Peptide Drug Conjugate (PDC)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1620"><a href="https://www.nervianoms.com/pipeline/#pipeline_ADC" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Antibody Drug Conjugate (ADC)</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1621"><a href="https://www.nervianoms.com/pipeline/#pipeline_payload_linkers" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Platform of Payload- Linkers</a></li> </ul> </li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page current-menu-item page_item page-item-42 current_page_item current-menu-ancestor current-menu-parent current_page_parent current_page_ancestor menu-item-has-children menu-item-4609"><a href="https://www.nervianoms.com/news-events-publications/" aria-current="page" class="elementor-item elementor-item-active" tabindex="-1">News/Events & Publications</a> <ul class="sub-menu elementor-nav-menu--dropdown"> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4610"><a href="https://www.nervianoms.com/news-events-publications//#news" aria-current="page" class="elementor-sub-item elementor-item-anchor" tabindex="-1">News</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4611"><a href="https://www.nervianoms.com/news-events-publications/#events" aria-current="page" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Events</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4612"><a href="https://www.nervianoms.com/news-events-publications/#publications" aria-current="page" class="elementor-sub-item elementor-item-anchor" tabindex="-1">Publications</a></li> </ul> </li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-80"><a href="https://www.nervianoms.com/careers/" class="elementor-item" tabindex="-1">Careers</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-81"><a href="https://www.nervianoms.com/contact-us/" class="elementor-item" tabindex="-1">Contact Us</a></li> </ul> </nav> </div> </div> <div class="elementor-element elementor-element-241c385 elementor-search-form--skin-full_screen elementor-widget elementor-widget-search-form" data-id="241c385" data-element_type="widget" data-settings="{"skin":"full_screen"}" data-widget_type="search-form.default"> <div class="elementor-widget-container"> <search role="search"> <form class="elementor-search-form" action="https://www.nervianoms.com" method="get"> <div class="elementor-search-form__toggle" role="button" tabindex="0" aria-label="Search"> <div class="e-font-icon-svg-container"><svg aria-hidden="true" class="e-font-icon-svg e-fas-search" viewBox="0 0 512 512" xmlns="http://www.w3.org/2000/svg"><path d="M505 442.7L405.3 343c-4.5-4.5-10.6-7-17-7H372c27.6-35.3 44-79.7 44-128C416 93.1 322.9 0 208 0S0 93.1 0 208s93.1 208 208 208c48.3 0 92.7-16.4 128-44v16.3c0 6.4 2.5 12.5 7 17l99.7 99.7c9.4 9.4 24.6 9.4 33.9 0l28.3-28.3c9.4-9.4 9.4-24.6.1-34zM208 336c-70.7 0-128-57.2-128-128 0-70.7 57.2-128 128-128 70.7 0 128 57.2 128 128 0 70.7-57.2 128-128 128z"></path></svg></div> </div> <div class="elementor-search-form__container"> <label class="elementor-screen-only" for="elementor-search-form-241c385">Search</label> <input id="elementor-search-form-241c385" placeholder="Search..." class="elementor-search-form__input" type="search" name="s" value=""> <div class="dialog-lightbox-close-button dialog-close-button" role="button" tabindex="0" aria-label="Close this search box."> <svg aria-hidden="true" class="e-font-icon-svg e-eicon-close" viewBox="0 0 1000 1000" xmlns="http://www.w3.org/2000/svg"><path d="M742 167L500 408 258 167C246 154 233 150 217 150 196 150 179 158 167 167 154 179 150 196 150 212 150 229 154 242 171 254L408 500 167 742C138 771 138 800 167 829 196 858 225 858 254 829L496 587 738 829C750 842 767 846 783 846 800 846 817 842 829 829 842 817 846 804 846 783 846 767 842 750 829 737L588 500 833 258C863 229 863 200 833 171 804 137 775 137 742 167Z"></path></svg> </div> </div> </form> </search> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-6bd5f4a7 e-flex e-con-boxed e-con e-parent" data-id="6bd5f4a7" data-element_type="container" data-settings="{"background_background":"classic"}"> <div class="e-con-inner"> <div class="elementor-element elementor-element-1fe5cc77 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget elementor-widget-theme-page-title elementor-page-title elementor-widget-heading" data-id="1fe5cc77" data-element_type="widget" data-widget_type="theme-page-title.default"> <div class="elementor-widget-container"> <h1 class="elementor-heading-title elementor-size-default">News/Events & Publications</h1> </div> </div> </div> </div> <div class="elementor-element elementor-element-90661a5 e-flex e-con-boxed e-con e-parent" data-id="90661a5" data-element_type="container" data-settings="{"background_background":"gradient"}"> <div class="e-con-inner"> </div> </div> <div class="elementor-element elementor-element-740a40dc e-flex e-con-boxed e-con e-parent" data-id="740a40dc" data-element_type="container" data-settings="{"background_background":"classic"}"> <div class="e-con-inner"> <div class="elementor-element elementor-element-620838ef e-con-full e-flex e-con e-child" data-id="620838ef" data-element_type="container"> <div class="elementor-element elementor-element-447fcb1 elementor-mobile-align-left elementor-widget elementor-widget-breadcrumbs" data-id="447fcb1" data-element_type="widget" data-widget_type="breadcrumbs.default"> <div class="elementor-widget-container"> <p id="breadcrumbs"><span><span><a href="https://www.nervianoms.com/">Home</a></span> / <span class="breadcrumb_last" aria-current="page">News/Events & Publications</span></span></p> </div> </div> </div> <div class="elementor-element elementor-element-163e1a6e e-con-full e-flex e-con e-child" data-id="163e1a6e" data-element_type="container"> <div class="elementor-element elementor-element-288c1219 elementor-widget__width-auto share elementor-view-default elementor-widget elementor-widget-icon" data-id="288c1219" data-element_type="widget" data-widget_type="icon.default"> <div class="elementor-widget-container"> <div class="elementor-icon-wrapper"> <a class="elementor-icon" href="#elementor-action%3Aaction%3Dpopup%3Aopen%26settings%3DeyJpZCI6IjQ2NSIsInRvZ2dsZSI6ZmFsc2V9"> <svg xmlns="http://www.w3.org/2000/svg" width="38.000000pt" height="31.000000pt" viewBox="0 0 38.000000 31.000000" preserveAspectRatio="xMidYMid meet"><g transform="translate(0.000000,31.000000) scale(0.100000,-0.100000)" fill="#000000" stroke="none"><path d="M218 260 c-3 -54 -3 -54 -40 -62 -79 -16 -151 -82 -165 -150 l-6 -33 31 32 c31 30 97 53 157 53 21 0 24 -5 27 -45 l3 -46 74 75 74 75 -76 78 -76 78 -3 -55z m75 -143 l-38 -38 -3 27 c-4 27 -4 27 -70 21 -37 -3 -76 -9 -86 -13 -14 -5 -17 -4 -12 4 12 19 77 49 124 57 37 6 42 10 42 33 0 26 0 26 40 -13 l40 -39 -37 -39z"></path></g></svg> </a> </div> </div> </div> <div class="elementor-element elementor-element-65855675 elementor-widget__width-initial elementor-widget elementor-widget-shortcode" data-id="65855675" data-element_type="widget" data-widget_type="shortcode.default"> <div class="elementor-widget-container"> <div class="elementor-shortcode"><div class="printfriendly pf-button pf-alignleft"> <a href="#" rel="nofollow" onclick="window.print(); return false;" title="Printer Friendly, PDF & Email"> <img src="https://nervianoms.com/wp-content/uploads/2024/10/Path-49.png" alt="Print Friendly, PDF & Email" class="pf-button-img" style="" /><span id="printfriendly-text2" class="pf-button-text"></span> </a> </div></div> </div> </div> </div> </div> </div> </div> <main id="content" class="site-main post-42 page type-page status-publish hentry"> <div class="page-content"> <div data-elementor-type="wp-page" data-elementor-id="42" class="elementor elementor-42" data-elementor-post-type="page"> <div class="elementor-element elementor-element-c23bf80 e-flex e-con-boxed e-con e-parent" data-id="c23bf80" data-element_type="container"> <div class="e-con-inner"> </div> </div> <div class="elementor-element elementor-element-6792319 e-flex e-con-boxed e-con e-parent" data-id="6792319" data-element_type="container"> <div class="e-con-inner"> <div class="elementor-element elementor-element-e219fbb elementor-widget elementor-widget-heading" data-id="e219fbb" data-element_type="widget" id="news" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">News</h2> </div> </div> <div class="elementor-element elementor-element-86f1ada elementor-grid-3 elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-widget elementor-widget-loop-grid" data-id="86f1ada" data-element_type="widget" data-settings="{"template_id":"4855","pagination_type":"load_more_on_click","_skin":"post","columns":"3","columns_tablet":"2","columns_mobile":"1","edit_handle_selector":"[data-elementor-type=\"loop-item\"]","load_more_spinner":{"value":"fas fa-spinner","library":"fa-solid"},"row_gap":{"unit":"px","size":"","sizes":[]},"row_gap_widescreen":{"unit":"px","size":"","sizes":[]},"row_gap_laptop":{"unit":"px","size":"","sizes":[]},"row_gap_tablet":{"unit":"px","size":"","sizes":[]},"row_gap_mobile":{"unit":"px","size":"","sizes":[]}}" data-widget_type="loop-grid.post"> <div class="elementor-widget-container"> <div class="elementor-loop-container elementor-grid"> <style id="loop-4855">.elementor-4855 .elementor-element.elementor-element-68ac9cb7{--display:flex;--flex-direction:column;--container-widget-width:100%;--container-widget-height:initial;--container-widget-flex-grow:0;--container-widget-align-self:initial;--flex-wrap-mobile:wrap;--justify-content:space-between;border-style:solid;--border-style:solid;border-width:1px 1px 1px 1px;--border-top-width:1px;--border-right-width:1px;--border-bottom-width:1px;--border-left-width:1px;border-color:#797979;--border-color:#797979;box-shadow:0px 0px 10px 0px rgba(0,0,0,0.5);--margin-top:0px;--margin-bottom:0px;--margin-left:0px;--margin-right:0px;--padding-top:10px;--padding-bottom:10px;--padding-left:10px;--padding-right:10px;}.elementor-widget-image-box .elementor-image-box-title{font-family:var( --e-global-typography-primary-font-family ), Sans-serif;}.elementor-widget-image-box .elementor-image-box-description{font-family:var( --e-global-typography-text-font-family ), Sans-serif;font-weight:var( --e-global-typography-text-font-weight );}.elementor-4855 .elementor-element.elementor-element-15654d92 > .elementor-widget-container{padding:0px 0px 0px 0px;}.elementor-4855 .elementor-element.elementor-element-15654d92 .elementor-image-box-wrapper{text-align:left;}.elementor-4855 .elementor-element.elementor-element-15654d92.elementor-position-right .elementor-image-box-img{margin-left:0px;}.elementor-4855 .elementor-element.elementor-element-15654d92.elementor-position-left .elementor-image-box-img{margin-right:0px;}.elementor-4855 .elementor-element.elementor-element-15654d92.elementor-position-top .elementor-image-box-img{margin-bottom:0px;}.elementor-4855 .elementor-element.elementor-element-15654d92 .elementor-image-box-title{margin-bottom:11px;color:var( --e-global-color-secondary );font-family:"Work Sans", Sans-serif;font-size:21px;line-height:1.6rem;}.elementor-4855 .elementor-element.elementor-element-15654d92 .elementor-image-box-wrapper .elementor-image-box-img{width:100%;}.elementor-4855 .elementor-element.elementor-element-15654d92 .elementor-image-box-img img{transition-duration:0.3s;}.elementor-4855 .elementor-element.elementor-element-15654d92 .elementor-image-box-description{color:var( --e-global-color-accent );font-family:"Work Sans", Sans-serif;font-size:0.8rem;font-weight:500;text-transform:uppercase;}.elementor-widget-heading .elementor-heading-title{font-family:var( --e-global-typography-primary-font-family ), Sans-serif;}.elementor-4855 .elementor-element.elementor-element-54a6eb92 > .elementor-widget-container{padding:10px 0px 0px 20px;border-style:solid;border-width:1px 0px 0px 0px;border-color:#EAEAEA;}.elementor-4855 .elementor-element.elementor-element-54a6eb92{text-align:left;}.elementor-4855 .elementor-element.elementor-element-54a6eb92 .elementor-heading-title{font-family:"Work Sans", Sans-serif;font-size:0.8rem;color:#848484;}@media(max-width:767px){.elementor-4855 .elementor-element.elementor-element-15654d92 .elementor-image-box-img{margin-bottom:0px;}}/* Start custom CSS for image-box, class: .elementor-element-15654d92 */.news-box .elementor-widget-image-box .elementor-image-box-content { padding: 0 20px!important; } .news-box .elementor-image-box-img img { object-fit: cover!important; height: 100%!important; width: 100%!important; }/* End custom CSS */</style> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4921 post-4921 post type-post status-publish format-standard has-post-thumbnail hentry category-linkedin category-news" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/nerviano-medical-sciences-presentation-from-the-8th-annual-ddr-inhibitors-summit-is-now-available/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/nerviano-medical-sciences-presentation-from-the-8th-annual-ddr-inhibitors-summit-is-now-available/" tabindex="-1"><picture fetchpriority="high" decoding="async" class="attachment-full size-full wp-image-4922"> <source type="image/webp" srcset="https://www.nervianoms.com/wp-content/uploads/2025/01/14fbafb8-3946-4f39-b85b-67052a61f13a.png.webp 1280w, https://www.nervianoms.com/wp-content/uploads/2025/01/14fbafb8-3946-4f39-b85b-67052a61f13a-300x188.png.webp 300w, https://www.nervianoms.com/wp-content/uploads/2025/01/14fbafb8-3946-4f39-b85b-67052a61f13a-1024x641.png.webp 1024w, https://www.nervianoms.com/wp-content/uploads/2025/01/14fbafb8-3946-4f39-b85b-67052a61f13a-768x481.png.webp 768w" sizes="(max-width: 1280px) 100vw, 1280px"/> <img fetchpriority="high" decoding="async" width="1280" height="801" src="https://www.nervianoms.com/wp-content/uploads/2025/01/14fbafb8-3946-4f39-b85b-67052a61f13a.png" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2025/01/14fbafb8-3946-4f39-b85b-67052a61f13a.png 1280w, https://www.nervianoms.com/wp-content/uploads/2025/01/14fbafb8-3946-4f39-b85b-67052a61f13a-300x188.png 300w, https://www.nervianoms.com/wp-content/uploads/2025/01/14fbafb8-3946-4f39-b85b-67052a61f13a-1024x641.png 1024w, https://www.nervianoms.com/wp-content/uploads/2025/01/14fbafb8-3946-4f39-b85b-67052a61f13a-768x481.png 768w" sizes="(max-width: 1280px) 100vw, 1280px"/> </picture> </a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/nerviano-medical-sciences-presentation-from-the-8th-annual-ddr-inhibitors-summit-is-now-available/">Nerviano Medical Sciences’ presentation from the 8<sup>th</sup> Annual DDR Inhibitors Summit is now available</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">January 31, 2025</p> </div> </div> </div> </div> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4836 post-4836 post type-post status-publish format-standard has-post-thumbnail hentry category-linkedin category-news" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/nerviano-medical-sciences-is-presenting-at-the-8th-annual-ddr-inhibitors-summit/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/nerviano-medical-sciences-is-presenting-at-the-8th-annual-ddr-inhibitors-summit/" tabindex="-1"><picture decoding="async" class="attachment-full size-full wp-image-4838"> <source type="image/webp" srcset="https://www.nervianoms.com/wp-content/uploads/2025/01/DDR-summit_cover-final1.png.webp 1277w, https://www.nervianoms.com/wp-content/uploads/2025/01/DDR-summit_cover-final1-300x188.png.webp 300w, https://www.nervianoms.com/wp-content/uploads/2025/01/DDR-summit_cover-final1-1024x642.png.webp 1024w, https://www.nervianoms.com/wp-content/uploads/2025/01/DDR-summit_cover-final1-768x481.png.webp 768w" sizes="(max-width: 1277px) 100vw, 1277px"/> <img decoding="async" width="1277" height="800" src="https://www.nervianoms.com/wp-content/uploads/2025/01/DDR-summit_cover-final1.png" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2025/01/DDR-summit_cover-final1.png 1277w, https://www.nervianoms.com/wp-content/uploads/2025/01/DDR-summit_cover-final1-300x188.png 300w, https://www.nervianoms.com/wp-content/uploads/2025/01/DDR-summit_cover-final1-1024x642.png 1024w, https://www.nervianoms.com/wp-content/uploads/2025/01/DDR-summit_cover-final1-768x481.png 768w" sizes="(max-width: 1277px) 100vw, 1277px"/> </picture> </a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/nerviano-medical-sciences-is-presenting-at-the-8th-annual-ddr-inhibitors-summit/">Nerviano Medical Sciences is presenting at the 8<sup>th</sup> Annual DDR Inhibitors Summit</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">January 22, 2025</p> </div> </div> </div> </div> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4826 post-4826 post type-post status-publish format-standard has-post-thumbnail hentry category-news tag-press-release" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/nerviano-medical-sciences-announces-fda-clearance-of-two-inds-for-its-parp1-selective-non-trapping-inhibitor-nms-293-to-start-clinical-studies-in-small-cell-lung-cancer-and-brca-wild-type-ovarian-car/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/nerviano-medical-sciences-announces-fda-clearance-of-two-inds-for-its-parp1-selective-non-trapping-inhibitor-nms-293-to-start-clinical-studies-in-small-cell-lung-cancer-and-brca-wild-type-ovarian-car/" tabindex="-1"><picture decoding="async" class="attachment-full size-full wp-image-4827"> <source type="image/webp" srcset="https://www.nervianoms.com/wp-content/uploads/2025/01/PARP1_2IND.png.webp 1300w, https://www.nervianoms.com/wp-content/uploads/2025/01/PARP1_2IND-300x189.png.webp 300w, https://www.nervianoms.com/wp-content/uploads/2025/01/PARP1_2IND-1024x646.png.webp 1024w, https://www.nervianoms.com/wp-content/uploads/2025/01/PARP1_2IND-768x484.png.webp 768w" sizes="(max-width: 1300px) 100vw, 1300px"/> <img decoding="async" width="1300" height="820" src="https://www.nervianoms.com/wp-content/uploads/2025/01/PARP1_2IND.png" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2025/01/PARP1_2IND.png 1300w, https://www.nervianoms.com/wp-content/uploads/2025/01/PARP1_2IND-300x189.png 300w, https://www.nervianoms.com/wp-content/uploads/2025/01/PARP1_2IND-1024x646.png 1024w, https://www.nervianoms.com/wp-content/uploads/2025/01/PARP1_2IND-768x484.png 768w" sizes="(max-width: 1300px) 100vw, 1300px"/> </picture> </a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/nerviano-medical-sciences-announces-fda-clearance-of-two-inds-for-its-parp1-selective-non-trapping-inhibitor-nms-293-to-start-clinical-studies-in-small-cell-lung-cancer-and-brca-wild-type-ovarian-car/">Nerviano Medical Sciences announces FDA clearance of two INDs for its PARP1-selective, non-trapping inhibitor NMS-293 to start clinical studies in small cell lung cancer and BRCA wild-type ovarian carcinoma</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">January 13, 2025</p> </div> </div> </div> </div> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4810 post-4810 post type-post status-publish format-standard has-post-thumbnail hentry category-news tag-press-release" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/nerviano-medical-sciences-s-r-l-announces-the-launch-of-a-new-clinical-trial-to-evaluate-nms-153-in-combination-with-atezolizumab-and-clinical-trial-supply-agreement-with-roche/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/nerviano-medical-sciences-s-r-l-announces-the-launch-of-a-new-clinical-trial-to-evaluate-nms-153-in-combination-with-atezolizumab-and-clinical-trial-supply-agreement-with-roche/" tabindex="-1"><picture loading="lazy" decoding="async" class="attachment-full size-full wp-image-4816"> <source type="image/webp" srcset="https://www.nervianoms.com/wp-content/uploads/2025/01/nms-153-atez_cover2-1.png.webp 1280w, https://www.nervianoms.com/wp-content/uploads/2025/01/nms-153-atez_cover2-1-300x187.png.webp 300w, https://www.nervianoms.com/wp-content/uploads/2025/01/nms-153-atez_cover2-1-1024x639.png.webp 1024w, https://www.nervianoms.com/wp-content/uploads/2025/01/nms-153-atez_cover2-1-768x479.png.webp 768w" sizes="(max-width: 1280px) 100vw, 1280px"/> <img loading="lazy" decoding="async" width="1280" height="799" src="https://www.nervianoms.com/wp-content/uploads/2025/01/nms-153-atez_cover2-1.png" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2025/01/nms-153-atez_cover2-1.png 1280w, https://www.nervianoms.com/wp-content/uploads/2025/01/nms-153-atez_cover2-1-300x187.png 300w, https://www.nervianoms.com/wp-content/uploads/2025/01/nms-153-atez_cover2-1-1024x639.png 1024w, https://www.nervianoms.com/wp-content/uploads/2025/01/nms-153-atez_cover2-1-768x479.png 768w" sizes="(max-width: 1280px) 100vw, 1280px"/> </picture> </a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/nerviano-medical-sciences-s-r-l-announces-the-launch-of-a-new-clinical-trial-to-evaluate-nms-153-in-combination-with-atezolizumab-and-clinical-trial-supply-agreement-with-roche/">Nerviano Medical Sciences S.r.l. Announces the Launch of a New Clinical Trial to Evaluate NMS-153 in Combination with Atezolizumab and Clinical Trial Supply Agreement with Roche</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">January 7, 2025</p> </div> </div> </div> </div> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4692 post-4692 post type-post status-publish format-standard has-post-thumbnail hentry category-news tag-press-release" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/nerviano-medical-sciences-nms-to-reacquire-world-wide-rights-of-nms-293-a-potent-highly-selective-non-trapping-brain-penetrant-parp1-inhibitor-with-promising-clinical-results/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/nerviano-medical-sciences-nms-to-reacquire-world-wide-rights-of-nms-293-a-potent-highly-selective-non-trapping-brain-penetrant-parp1-inhibitor-with-promising-clinical-results/" tabindex="-1"><picture loading="lazy" decoding="async" class="attachment-full size-full wp-image-4695"> <source type="image/webp" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/cover_PARP1_25112024-20241125-150609.png.webp 1285w, https://www.nervianoms.com/wp-content/uploads/2024/11/cover_PARP1_25112024-20241125-150609-300x187.png.webp 300w, https://www.nervianoms.com/wp-content/uploads/2024/11/cover_PARP1_25112024-20241125-150609-1024x637.png.webp 1024w, https://www.nervianoms.com/wp-content/uploads/2024/11/cover_PARP1_25112024-20241125-150609-768x478.png.webp 768w" sizes="(max-width: 1285px) 100vw, 1285px"/> <img loading="lazy" decoding="async" width="1285" height="799" src="https://www.nervianoms.com/wp-content/uploads/2024/11/cover_PARP1_25112024-20241125-150609.png" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/cover_PARP1_25112024-20241125-150609.png 1285w, https://www.nervianoms.com/wp-content/uploads/2024/11/cover_PARP1_25112024-20241125-150609-300x187.png 300w, https://www.nervianoms.com/wp-content/uploads/2024/11/cover_PARP1_25112024-20241125-150609-1024x637.png 1024w, https://www.nervianoms.com/wp-content/uploads/2024/11/cover_PARP1_25112024-20241125-150609-768x478.png 768w" sizes="(max-width: 1285px) 100vw, 1285px"/> </picture> </a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/nerviano-medical-sciences-nms-to-reacquire-world-wide-rights-of-nms-293-a-potent-highly-selective-non-trapping-brain-penetrant-parp1-inhibitor-with-promising-clinical-results/">Nerviano Medical Sciences (NMS) to Reacquire World-Wide Rights of NMS-293, a Potent, Highly Selective, Non-Trapping, Brain-Penetrant PARP1 Inhibitor with Promising Clinical Results</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">November 25, 2024</p> </div> </div> </div> </div> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4345 post-4345 post type-post status-publish format-standard has-post-thumbnail hentry category-news tag-press-release" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/nerviano-medical-sciences-announces-strategic-acquisition-of-atamparib-a-phase-ii-ready-parp7-inhibitor-from-ribon-therapeutics/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/nerviano-medical-sciences-announces-strategic-acquisition-of-atamparib-a-phase-ii-ready-parp7-inhibitor-from-ribon-therapeutics/" tabindex="-1"><img loading="lazy" decoding="async" width="400" height="250" src="https://www.nervianoms.com/wp-content/uploads/2024/11/atamparib-202411-400x250-1.png" class="attachment-full size-full wp-image-4346" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/atamparib-202411-400x250-1.png 400w, https://www.nervianoms.com/wp-content/uploads/2024/11/atamparib-202411-400x250-1-300x188.png 300w" sizes="(max-width: 400px) 100vw, 400px" /></a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/nerviano-medical-sciences-announces-strategic-acquisition-of-atamparib-a-phase-ii-ready-parp7-inhibitor-from-ribon-therapeutics/">Nerviano Medical Sciences Announces Strategic acquisition of atamparib, a Phase II-ready PARP7 Inhibitor, from Ribon Therapeutics</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">November 15, 2024</p> </div> </div> </div> </div> </div> <span class="e-load-more-spinner"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-spinner" viewBox="0 0 512 512" xmlns="http://www.w3.org/2000/svg"><path d="M304 48c0 26.51-21.49 48-48 48s-48-21.49-48-48 21.49-48 48-48 48 21.49 48 48zm-48 368c-26.51 0-48 21.49-48 48s21.49 48 48 48 48-21.49 48-48-21.49-48-48-48zm208-208c-26.51 0-48 21.49-48 48s21.49 48 48 48 48-21.49 48-48-21.49-48-48-48zM96 256c0-26.51-21.49-48-48-48S0 229.49 0 256s21.49 48 48 48 48-21.49 48-48zm12.922 99.078c-26.51 0-48 21.49-48 48s21.49 48 48 48 48-21.49 48-48c0-26.509-21.491-48-48-48zm294.156 0c-26.51 0-48 21.49-48 48s21.49 48 48 48 48-21.49 48-48c0-26.509-21.49-48-48-48zM108.922 60.922c-26.51 0-48 21.49-48 48s21.49 48 48 48 48-21.49 48-48-21.491-48-48-48z"></path></svg> </span> <div class="e-load-more-anchor" data-page="1" data-max-page="13" data-next-page="https://www.nervianoms.com/news-events-publications/2/"></div> <div class="e-loop__load-more elementor-button-wrapper"> <a href="#" class="elementor-button-link elementor-button" role="button"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-text">Load More</span> </span> </a> </div> <div class="e-load-more-message"></div> </div> </div> <div class="elementor-element elementor-element-cbd5cae elementor-widget elementor-widget-heading" data-id="cbd5cae" data-element_type="widget" id="events" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">Events</h2> </div> </div> <div class="elementor-element elementor-element-b25b266 elementor-grid-3 elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-widget elementor-widget-loop-grid" data-id="b25b266" data-element_type="widget" data-settings="{"template_id":"4855","pagination_type":"load_more_on_click","_skin":"post","columns":"3","columns_tablet":"2","columns_mobile":"1","edit_handle_selector":"[data-elementor-type=\"loop-item\"]","load_more_spinner":{"value":"fas fa-spinner","library":"fa-solid"},"row_gap":{"unit":"px","size":"","sizes":[]},"row_gap_widescreen":{"unit":"px","size":"","sizes":[]},"row_gap_laptop":{"unit":"px","size":"","sizes":[]},"row_gap_tablet":{"unit":"px","size":"","sizes":[]},"row_gap_mobile":{"unit":"px","size":"","sizes":[]}}" data-widget_type="loop-grid.post"> <div class="elementor-widget-container"> <div class="elementor-loop-container elementor-grid"> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4295 post-4295 post type-post status-publish format-standard has-post-thumbnail hentry category-events" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/nerviano-medical-sciences-at-bio-europe-2024/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/nerviano-medical-sciences-at-bio-europe-2024/" tabindex="-1"><img loading="lazy" decoding="async" width="1276" height="798" src="https://www.nervianoms.com/wp-content/uploads/2024/11/bio-europe2024.png" class="attachment-full size-full wp-image-4297" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/bio-europe2024.png 1276w, https://www.nervianoms.com/wp-content/uploads/2024/11/bio-europe2024-300x188.png 300w, https://www.nervianoms.com/wp-content/uploads/2024/11/bio-europe2024-1024x640.png 1024w, https://www.nervianoms.com/wp-content/uploads/2024/11/bio-europe2024-768x480.png 768w" sizes="(max-width: 1276px) 100vw, 1276px" /></a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/nerviano-medical-sciences-at-bio-europe-2024/">Nerviano Medical Sciences at BIO-Europe 2024</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">October 11, 2024</p> </div> </div> </div> </div> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4274 post-4274 post type-post status-publish format-standard has-post-thumbnail hentry category-events" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/nerviano-medical-sciences-will-be-exhibiting-at-the-sci-2024-xxviii-national-congress/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/nerviano-medical-sciences-will-be-exhibiting-at-the-sci-2024-xxviii-national-congress/" tabindex="-1"><img loading="lazy" decoding="async" width="1276" height="798" src="https://www.nervianoms.com/wp-content/uploads/2024/11/cover-web.png" class="attachment-full size-full wp-image-4275" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/cover-web.png 1276w, https://www.nervianoms.com/wp-content/uploads/2024/11/cover-web-300x188.png 300w, https://www.nervianoms.com/wp-content/uploads/2024/11/cover-web-1024x640.png 1024w, https://www.nervianoms.com/wp-content/uploads/2024/11/cover-web-768x480.png 768w" sizes="(max-width: 1276px) 100vw, 1276px" /></a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/nerviano-medical-sciences-will-be-exhibiting-at-the-sci-2024-xxviii-national-congress/">Nerviano Medical Sciences will be exhibiting at the SCI-2024 – XXVIII National Congress</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">August 6, 2024</p> </div> </div> </div> </div> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4251 post-4251 post type-post status-publish format-standard has-post-thumbnail hentry category-events" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/nerviano-medical-sciences-s-r-l-is-presenting-at-the-swiss-biotech-day-2024-in-basel/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/nerviano-medical-sciences-s-r-l-is-presenting-at-the-swiss-biotech-day-2024-in-basel/" tabindex="-1"><img loading="lazy" decoding="async" width="1280" height="798" src="https://www.nervianoms.com/wp-content/uploads/2024/11/isacchi_swiss_web.png" class="attachment-full size-full wp-image-4252" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/isacchi_swiss_web.png 1280w, https://www.nervianoms.com/wp-content/uploads/2024/11/isacchi_swiss_web-300x187.png 300w, https://www.nervianoms.com/wp-content/uploads/2024/11/isacchi_swiss_web-1024x638.png 1024w, https://www.nervianoms.com/wp-content/uploads/2024/11/isacchi_swiss_web-768x479.png 768w" sizes="(max-width: 1280px) 100vw, 1280px" /></a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/nerviano-medical-sciences-s-r-l-is-presenting-at-the-swiss-biotech-day-2024-in-basel/">Nerviano Medical Sciences S.r.l. is presenting at the SWISS BIOTECH DAY 2024 in Basel!</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">April 22, 2024</p> </div> </div> </div> </div> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4249 post-4249 post type-post status-publish format-standard has-post-thumbnail hentry category-events" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/nerviano-medical-sciences-s-r-l-will-attend-the-swiss-biotech-day-2024-partnering-event-in-basel-switzerland/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/nerviano-medical-sciences-s-r-l-will-attend-the-swiss-biotech-day-2024-partnering-event-in-basel-switzerland/" tabindex="-1"><img loading="lazy" decoding="async" width="1267" height="780" src="https://www.nervianoms.com/wp-content/uploads/2024/11/NMS_web.jpg" class="attachment-full size-full wp-image-4250" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/NMS_web.jpg 1267w, https://www.nervianoms.com/wp-content/uploads/2024/11/NMS_web-300x185.jpg 300w, https://www.nervianoms.com/wp-content/uploads/2024/11/NMS_web-1024x630.jpg 1024w, https://www.nervianoms.com/wp-content/uploads/2024/11/NMS_web-768x473.jpg 768w" sizes="(max-width: 1267px) 100vw, 1267px" /></a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/nerviano-medical-sciences-s-r-l-will-attend-the-swiss-biotech-day-2024-partnering-event-in-basel-switzerland/">Nerviano Medical Sciences S.r.l. will attend the SWISS BIOTECH DAY 2024 partnering event in Basel, Switzerland</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">April 12, 2024</p> </div> </div> </div> </div> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4109 post-4109 post type-post status-publish format-standard has-post-thumbnail hentry category-events" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/cphi-worldwide/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/cphi-worldwide/" tabindex="-1"><picture loading="lazy" decoding="async" class="attachment-full size-full wp-image-4060"> <source type="image/webp" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/Communication.jpg.webp 1276w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-300x188.jpg.webp 300w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-1024x640.jpg.webp 1024w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-768x480.jpg.webp 768w" sizes="(max-width: 1276px) 100vw, 1276px"/> <img loading="lazy" decoding="async" width="1276" height="798" src="https://www.nervianoms.com/wp-content/uploads/2024/11/Communication.jpg" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/Communication.jpg 1276w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-300x188.jpg 300w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-1024x640.jpg 1024w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-768x480.jpg 768w" sizes="(max-width: 1276px) 100vw, 1276px"/> </picture> </a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/cphi-worldwide/">CPhI Worldwide</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">August 3, 2021</p> </div> </div> </div> </div> <div data-elementor-type="loop-item" data-elementor-id="4855" class="elementor elementor-4855 e-loop-item e-loop-item-4066 post-4066 post type-post status-publish format-standard has-post-thumbnail hentry category-events tag-meetings-and-congresses" data-elementor-post-type="elementor_library" data-custom-edit-handle="1"> <div class="elementor-element elementor-element-68ac9cb7 e-con-full news-box e-flex e-con e-parent" data-id="68ac9cb7" data-element_type="container"> <a class="eael-wrapper-link-15654d92 --eael-wrapper-link-tag" href="https://www.nervianoms.com/61st-annual-meeting-of-the-italian-cancer-society/"></a> <div data-eael-wrapper-link="eael-wrapper-link-15654d92" class="elementor-element elementor-element-15654d92 elementor-position-top elementor-widget elementor-widget-image-box" data-id="15654d92" data-element_type="widget" data-widget_type="image-box.default"> <div class="elementor-widget-container"> <div class="elementor-image-box-wrapper"><figure class="elementor-image-box-img"><a href="https://www.nervianoms.com/61st-annual-meeting-of-the-italian-cancer-society/" tabindex="-1"><picture loading="lazy" decoding="async" class="attachment-full size-full wp-image-4060"> <source type="image/webp" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/Communication.jpg.webp 1276w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-300x188.jpg.webp 300w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-1024x640.jpg.webp 1024w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-768x480.jpg.webp 768w" sizes="(max-width: 1276px) 100vw, 1276px"/> <img loading="lazy" decoding="async" width="1276" height="798" src="https://www.nervianoms.com/wp-content/uploads/2024/11/Communication.jpg" alt="" srcset="https://www.nervianoms.com/wp-content/uploads/2024/11/Communication.jpg 1276w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-300x188.jpg 300w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-1024x640.jpg 1024w, https://www.nervianoms.com/wp-content/uploads/2024/11/Communication-768x480.jpg 768w" sizes="(max-width: 1276px) 100vw, 1276px"/> </picture> </a></figure><div class="elementor-image-box-content"><h3 class="elementor-image-box-title"><a href="https://www.nervianoms.com/61st-annual-meeting-of-the-italian-cancer-society/">61st annual meeting of the Italian Cancer Society</a></h3><p class="elementor-image-box-description">Read More »</p></div></div> </div> </div> <div class="elementor-element elementor-element-54a6eb92 date-box elementor-widget elementor-widget-heading" data-id="54a6eb92" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <p class="elementor-heading-title elementor-size-default">November 1, 2020</p> </div> </div> </div> </div> </div> <span class="e-load-more-spinner"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-spinner" viewBox="0 0 512 512" xmlns="http://www.w3.org/2000/svg"><path d="M304 48c0 26.51-21.49 48-48 48s-48-21.49-48-48 21.49-48 48-48 48 21.49 48 48zm-48 368c-26.51 0-48 21.49-48 48s21.49 48 48 48 48-21.49 48-48-21.49-48-48-48zm208-208c-26.51 0-48 21.49-48 48s21.49 48 48 48 48-21.49 48-48-21.49-48-48-48zM96 256c0-26.51-21.49-48-48-48S0 229.49 0 256s21.49 48 48 48 48-21.49 48-48zm12.922 99.078c-26.51 0-48 21.49-48 48s21.49 48 48 48 48-21.49 48-48c0-26.509-21.491-48-48-48zm294.156 0c-26.51 0-48 21.49-48 48s21.49 48 48 48 48-21.49 48-48c0-26.509-21.49-48-48-48zM108.922 60.922c-26.51 0-48 21.49-48 48s21.49 48 48 48 48-21.49 48-48-21.491-48-48-48z"></path></svg> </span> <div class="e-load-more-anchor" data-page="1" data-max-page="8" data-next-page="https://www.nervianoms.com/news-events-publications/2/"></div> <div class="e-loop__load-more elementor-button-wrapper"> <a href="#" class="elementor-button-link elementor-button" role="button"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-text">Load More</span> </span> </a> </div> <div class="e-load-more-message"></div> </div> </div> </div> </div> <div class="elementor-element elementor-element-c2e2599 publications e-flex e-con-boxed e-con e-parent" data-id="c2e2599" data-element_type="container"> <div class="e-con-inner"> <div class="elementor-element elementor-element-7ddaaab elementor-widget elementor-widget-heading" data-id="7ddaaab" data-element_type="widget" id="publications" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h2 class="elementor-heading-title elementor-size-default">Publications</h2> </div> </div> <div class="elementor-element elementor-element-e00c32b elementor-align-right elementor-widget elementor-widget-button" data-id="e00c32b" data-element_type="widget" data-widget_type="button.default"> <div class="elementor-widget-container"> <div class="elementor-button-wrapper"> <a class="elementor-button elementor-size-sm" role="button"> <span class="elementor-button-content-wrapper"> <span class="elementor-button-text">Expand All</span> </span> </a> </div> </div> </div> <div class="elementor-element elementor-element-a491567 elementor-widget elementor-widget-n-accordion" data-id="a491567" data-element_type="widget" data-settings="{"max_items_expended":"multiple","default_state":"expanded","n_accordion_animation_duration":{"unit":"ms","size":400,"sizes":[]}}" data-widget_type="nested-accordion.default"> <div class="elementor-widget-container"> <div class="e-n-accordion" aria-label="Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys"> <details id="e-n-accordion-item-1720" class="e-n-accordion-item" open> <summary class="e-n-accordion-item-title" data-accordion-index="1" tabindex="0" aria-expanded="true" aria-controls="e-n-accordion-item-1720" > <span class='e-n-accordion-item-title-header'><div class="e-n-accordion-item-title-text"> 2024 </div></span> <span class='e-n-accordion-item-title-icon'> <span class='e-opened' ><svg aria-hidden="true" class="e-font-icon-svg e-fas-minus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> <span class='e-closed'><svg aria-hidden="true" class="e-font-icon-svg e-fas-plus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> </span> </summary> <div role="region" aria-labelledby="e-n-accordion-item-1720" class="elementor-element elementor-element-40af580 e-con-full e-flex e-con e-child" data-id="40af580" data-element_type="container"> <div class="elementor-element elementor-element-e51ed40 elementor-widget elementor-widget-eael-feature-list" data-id="e51ed40" data-element_type="widget" data-widget_type="eael-feature-list.default"> <div class="elementor-widget-container"> <div class="-icon-position-left -tablet-icon-position-left -mobile-icon-position-left"> <ul id="eael-feature-list-e51ed40" class="eael-feature-list-items square stacked eael-feature-list-vertical"> <li class="eael-feature-list-item elementor-repeater-item-6bfb5c4"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-0"href="https://www.nature.com/articles/s41467-024-53163-y" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.nature.com/articles/s41467-024-53163-y" target="_blank">Integrative ensemble modelling of cetuximab sensitivity in colorectal cancer patient-derived xenografts</a></h4> <p class="eael-feature-list-content">Perron U, Grassi E, Chatzipli A, Viviani M, Karakoc E, Trastulla L, Brochier LM, Isella C, Zanella ER, Klett H, Molineris I, Schueler J, Esteller M, Medico E, Conte N, McDermott U, Trusolino L, Bertotti A, Iorio F <br> Nat Commun (2024), 15(1), 9139 </p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-bc0780f"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-1"href="https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01266" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c01266" target="_blank">New LsrK Ligands as AI-2 Quorum Sensing Interfering Compounds against Biofilm Formation</a></h4> <p class="eael-feature-list-content">Milli G, Pellegrini A, Listro R, Fasolini M, Pagano K, Ragona L, Pietrocola G, Linciano P, Collina S <br> Med Chem (2024), 67(20), 18139-18156</p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-a705bfc"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-2"href="https://pubs.acs.org/doi/10.1021/acs.joc.3c02386" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://pubs.acs.org/doi/10.1021/acs.joc.3c02386" target="_blank">Present Scenario and Future Landscape of Payloads for ADCs: Focus on DNA- Interacting Agents.</a></h4> <p class="eael-feature-list-content">Valsasina B., Orsini P., Terenghi C., Ocana A.<br> <em>Pharmaceuticals 2024, 17, 1338.</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-3394ca3"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-3"href="https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202402175?af=R%5d" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202402175?af=R%5d" target="_blank">Visible Light Promoted Site-Specific Functionalization of α-Acyloxy Carboxamides: Unlocking a Forbidden Chemical Space in the Passerini Reaction</a></h4> <p class="eael-feature-list-content">Brunelli F, Quartieri F, Miletto I, Pulici M, Papeo G, Tron GC <br> <em>Chemistry (2024), Aug 21. Online ahead of print.</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-f1b9087"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-4"href="https://www.sciencedirect.com/science/article/abs/pii/S0223523424002551?via%3Dihub" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.sciencedirect.com/science/article/abs/pii/S0223523424002551?via%3Dihub" target="_blank">Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors</a></h4> <p class="eael-feature-list-content">Cervi G, D’Alessio R, Bindi S, Buffa L, Burocchi A, Canevari G, Modugno M, Motto I, Saturno G, Orsini P <br> <em>Eur J Med Chem (2024), 270, 116375</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-b5328b9"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-5"href="https://pubs.acs.org/doi/10.1021/acs.joc.3c02386" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://pubs.acs.org/doi/10.1021/acs.joc.3c02386" target="_blank">Photocatalytic radical coupling of organoborates with α-Halogenated electron-poor olefins</a></h4> <p class="eael-feature-list-content">Caldarelli M, Rezzi SJ, Colombo N, Pirali T, Papeo G <br> <em>J Org Chem (2024), 5, 89(1), 633-643</em></p> </div> </li> </ul> </div> </div> </div> <div class="elementor-element elementor-element-8bbbc85 elementor-widget elementor-widget-heading" data-id="8bbbc85" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h4 class="elementor-heading-title elementor-size-default">Posters</h4> </div> </div> <div class="elementor-element elementor-element-d9a3676 elementor-widget elementor-widget-eael-feature-list" data-id="d9a3676" data-element_type="widget" data-widget_type="eael-feature-list.default"> <div class="elementor-widget-container"> <div class="-icon-position-left -tablet-icon-position-left -mobile-icon-position-left"> <ul id="eael-feature-list-d9a3676" class="eael-feature-list-items square stacked eael-feature-list-vertical"> <li class="eael-feature-list-item elementor-repeater-item-77a27b6"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-0"href="https://form.jotform.com/241192707868365" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://form.jotform.com/241192707868365" target="_blank">A novel platform of diversified cytotoxins and targeted payloads to drive ADC innovation </a></h4> <p class="eael-feature-list-content">P. Orsini, M. Salsa, S. Rizzi, U. Cucchi, D. Faiardi, A. Burocchi, A. Ciavolella, R. Lupi, F. Gasparri, B. Valsasina. <br> AACR Annual Meeting 2024; April 5-10, 2024; San Diego <br> <a href="https://aacrjournals.org/cancerres/article/84/6_Supplement/5805/735321/Abstract-5805-A-novel-platform-of-diversified%5d" target="blank">Abstract 5805</a> <br> <em>Cancer Res (2024) 84 (6_Supplement) </em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-a705bfc"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-1"href="https://form.jotform.com/241094256420046" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://form.jotform.com/241094256420046" target="_blank">The MPS1/TTK inhibitor, NMS-01940153, synergizes with tisotumab vedotin in colorectal cancer </a></h4> <p class="eael-feature-list-content">G. Texido, F. Gasparri, A. Ciavolella, L. Gianellini, A. Burocchi, I. Fraietta, A.E. Pedersen, A. Ocaña, R. Colombo, D. Roberti, L. Mahnke, C. Perrera <br> AACR Annual Meeting 2024; April 5-10, 2024; San Diego <br> <a href="https://aacrjournals.org/cancerres/article/84/6_Supplement/509/737622/Abstract-509-The-MPS1-TTK-inhibitor-NMS-01940153%5d" target="blank">Abstract 509</a> <br> <em>Cancer Res (2024) 84 (6_Supplement) </em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-cd1d1b1"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-2"href="https://form.jotform.com/242104372260343" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://form.jotform.com/242104372260343" target="_blank">Development of 14-amino-anthracyclines as novel payloads for ADC production showing potent anti-tumor activity and improved safety profile</a></h4> <p class="eael-feature-list-content">P. Orsini, M. Salsa, A. Burocchi, A. Ciavolella, U. Cucchi, D. Faiardi, S. Rizzi, F. Gasparri, B. Valsasina <br> 38th National Medicinal Chemistry Symposium; June 23-26, 2024; Seattle, WA.</p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-5c31544"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-3"href="https://form.jotform.com/242104189352351" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://form.jotform.com/242104189352351" target="_blank">A payload-linker generating machine to quickly move from small molecules to characterized tool ADCs and PDCs </a></h4> <p class="eael-feature-list-content">R. Lupi, P. Orsini, M. Salsa, S. Rizzi, U. Cucchi, D. Faiardi, A. Burocchi, A. Ciavolella, F. Gasparri, B. Valsasina <br> 14th World ADC London 2024; March 12-15, 2024; London, UK </p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-603c88b"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <span class="eael-feature-list-icon fl-icon-4"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </span> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title">Discovery of NMS-0963, a potent, selective and orally available Syk inhibitor with outstanding preclinical activity in diffuse large B-cell lymphoma </h4> <p class="eael-feature-list-content"> L. Buffa, G. Cervi, R. D'Alessio, S. Bindi, A. Burocchi, G. Canevari, M. Modugno, I. Motto, G. Saturno, P. Orsini <br> 58th International Conference on Medicinal Chemistry (RICT 2024); July 3-5, 2024; Bordeaux, France </p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-61f5fc7"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <span class="eael-feature-list-icon fl-icon-5"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </span> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title">Photocatalytic Giese reaction of boron-containing compounds with α-Halogenated electron-poor olefins </h4> <p class="eael-feature-list-content">M. Caldarelli, S.J. Rezzi, N. Colombo, T.Pirali, G. Papeo <br> EFMC-ISMC 2024; XXVIII EFMC International Symposium on Medicinal Chemistry; September 1-5, 2024; Rome, Italy <br> <a href="https://www.efmc-ismc.org/v2/data/1725266112EFMC-ISMC-2024-BoA-web-FINAL.pdf" target="blank">Abstract P411</a> <br> </p> </div> </li> </ul> </div> </div> </div> </div> </details> <details id="e-n-accordion-item-1721" class="e-n-accordion-item" > <summary class="e-n-accordion-item-title" data-accordion-index="2" tabindex="-1" aria-expanded="false" aria-controls="e-n-accordion-item-1721" > <span class='e-n-accordion-item-title-header'><div class="e-n-accordion-item-title-text"> 2023 </div></span> <span class='e-n-accordion-item-title-icon'> <span class='e-opened' ><svg aria-hidden="true" class="e-font-icon-svg e-fas-minus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> <span class='e-closed'><svg aria-hidden="true" class="e-font-icon-svg e-fas-plus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> </span> </summary> <div role="region" aria-labelledby="e-n-accordion-item-1721" class="elementor-element elementor-element-5d51721 e-con-full e-flex e-con e-child" data-id="5d51721" data-element_type="container"> <div class="elementor-element elementor-element-dd3e46b elementor-widget elementor-widget-eael-feature-list" data-id="dd3e46b" data-element_type="widget" data-widget_type="eael-feature-list.default"> <div class="elementor-widget-container"> <div class="-icon-position-left -tablet-icon-position-left -mobile-icon-position-left"> <ul id="eael-feature-list-dd3e46b" class="eael-feature-list-items square stacked eael-feature-list-vertical"> <li class="eael-feature-list-item elementor-repeater-item-a705bfc"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-0"href="https://aacrjournals.org/mct/article/22/12/1465/730263/Novel-Thienoduocarmycin-Trastuzumab-ADC%5d" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://aacrjournals.org/mct/article/22/12/1465/730263/Novel-Thienoduocarmycin-Trastuzumab-ADC%5d" target="_blank">Novel Thienoduocarmycin-Trastuzumab ADC Demonstrates Strong Antitumor Efficacy with Favorable Safety Profile in Preclinical Studies </a></h4> <p class="eael-feature-list-content">Valsasina B, Orsini P, Caruso M, Albanese C, Ciavolella A, Cucchi U, Fraietta I, Melillo N, Fiorentini F, Rizzi S, Salsa M, Isacchi A, Gasparri F <br> <em>Mol Cancer Ther (2023), 22(12), 1465-1478</em></p> </div> </li> </ul> </div> </div> </div> <div class="elementor-element elementor-element-df8472b elementor-widget elementor-widget-heading" data-id="df8472b" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h4 class="elementor-heading-title elementor-size-default">Posters</h4> </div> </div> <div class="elementor-element elementor-element-9305f52 elementor-widget elementor-widget-eael-feature-list" data-id="9305f52" data-element_type="widget" data-widget_type="eael-feature-list.default"> <div class="elementor-widget-container"> <div class="-icon-position-left -tablet-icon-position-left -mobile-icon-position-left"> <ul id="eael-feature-list-9305f52" class="eael-feature-list-items square stacked eael-feature-list-vertical"> <li class="eael-feature-list-item elementor-repeater-item-a705bfc"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <span class="eael-feature-list-icon fl-icon-0"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </span> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title">NMS-0963 is a novel potent, selective and orally available Syk inhibitor with promising preclinical activity in diffuse large B-cell lymphoma </h4> <p class="eael-feature-list-content">G. Saturno, M. Modugno, P. Orsini, G. Cervi, L. Buffa, I. Motto, N. Avanzi, M. Montemartini, F. Gasparri, G. Texido, A. Galvani, A. Isacchi <br> AACR Annual Meeting 2023; 2023 April 14-19; Orlando, FL.<br> <a href="https://aacrjournals.org/cancerres/article/83/7_Supplement/4036/724682/Abstract-4036-NMS-0963-is-a-novel-potent-selective%5d" target="blank">Abstract 4036</a> <br> <em>Cancer Res (2023) 83 (7_Supplement) </em> </p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-f22a3a2"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <span class="eael-feature-list-icon fl-icon-1"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </span> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title">NMS-812, a novel potent PERK inhibitor that also inhibits GCN2, exhibits strong anti tumor activity as single agent and in combination in preclinical models. </h4> <p class="eael-feature-list-content">C. Perrera, M. Pulici, P. Banfi, N. Avanzi, D. Carenzi, D. Casero, A. Ciavolella, L. Gianellini, F. Gasparri, G. Saturno, B. Valsasina, E. Ardini, A. Montagnoli, A. Galvani, A. Isacchi. <br> <em>AACR Annual Meeting 2023; 2023 April 14-19; Orlando, FL. </em> <br> <a href="https://aacrjournals.org/cancerres/article/83/7_Supplement/1615/722144/Abstract-1615-NMS-812-a-novel-potent-PERK%5d" target="blank">Abstract 1615</a> <br> <em>Cancer Res (2023) 83 (7_Supplement)</em> </p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-a1d105d"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-2"href="https://www.nmsgroup.it/wp-content/uploads/2023/05/ASCO23_Abstract_TPS4185_Poster-499a_MPSA-001_FINAL.pdf" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.nmsgroup.it/wp-content/uploads/2023/05/ASCO23_Abstract_TPS4185_Poster-499a_MPSA-001_FINAL.pdf" target="_blank"> Phase II study on safety and efficacy of NMS-01940153E, an MPS1 inhibitor with first-in class potential, in adult patients with unresectable hepatocellular carcinoma (HCC) previously treated with systemic therapy. </a></h4> <p class="eael-feature-list-content">L. Rimassa, M. Reig, S. Damian, D. Roberti, S. Maruzzelli, F. Gasparri, P. Ghioni, M.T. De Pietro, T. Pressiani, M. Sanduzzi Zamparelli, M. Duca, A. Montagnoli, A. Galvani, E. Ardini, A. Isacchi, C. Davite, P. Crivori, L. Mahnke <br> 2023 ASCO Annual Meeting; June 2-6, 2023; at Chicago, IL. <br> <a href="https://www.nmsgroup.it/wp-content/uploads/2023/05/2023white_ASCO23template_MPSA-001_Abstract-TPS4185_FINAL-slide-deck.pdf" target="blank">Slide deck</a> <br> <a href="https://ascopubs.org/doi/10.1200/JCO.2023.41.16_suppl.TPS4185" target="blank">Abstract TPS4185 </a> <br> <em> Journal of Clinical Oncology Volume 41, Number 16_suppl </em> </p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-1d0a14c"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-3"href="https://www.nmsgroup.it/wp-content/uploads/2023/10/Poster48x96_v6.pdf" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.nmsgroup.it/wp-content/uploads/2023/10/Poster48x96_v6.pdf" target="_blank">Initial Results from 2 Phase I Studies of NMS-03305293, a Selective PARP1 Inhibitor </a></h4> <p class="eael-feature-list-content"> M. Geurts; D. Gramatzki; S. Merler; M. Duca; F. Girardi; U. T. Sener; D. Roberti; G. Saturno; P. <br> Crivori; A. Montagnoli; L. Mahnke; S. Fu; P. Gaviani; K. A. Jaeckle; J. Zhang; Y. Shi; V. <br> Guarneri; M. Weller; S. H. Kizilbash; M. J. van den Bent; M. Milella; S. Damian <br> AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; <br> October 11-15 2023; Boston, MA. <br> <a href="https://aacrjournals.org/mct/article/22/12_Supplement/LB_A12/730469/Abstract-LB-A12-Initial-results-from-2-Phase-I%5d" target="blank">Abstract LB_A12</a> <br> Mol Cancer Ther (2023) 22 (12_Supplement): LB_A12 </p> </div> </li> </ul> </div> </div> </div> </div> </details> <details id="e-n-accordion-item-1722" class="e-n-accordion-item" > <summary class="e-n-accordion-item-title" data-accordion-index="3" tabindex="-1" aria-expanded="false" aria-controls="e-n-accordion-item-1722" > <span class='e-n-accordion-item-title-header'><div class="e-n-accordion-item-title-text"> 2022 </div></span> <span class='e-n-accordion-item-title-icon'> <span class='e-opened' ><svg aria-hidden="true" class="e-font-icon-svg e-fas-minus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> <span class='e-closed'><svg aria-hidden="true" class="e-font-icon-svg e-fas-plus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> </span> </summary> <div role="region" aria-labelledby="e-n-accordion-item-1722" class="elementor-element elementor-element-de1ae72 e-con-full e-flex e-con e-child" data-id="de1ae72" data-element_type="container"> <div class="elementor-element elementor-element-e6f9815 elementor-widget elementor-widget-eael-feature-list" data-id="e6f9815" data-element_type="widget" data-widget_type="eael-feature-list.default"> <div class="elementor-widget-container"> <div class="-icon-position-left -tablet-icon-position-left -mobile-icon-position-left"> <ul id="eael-feature-list-e6f9815" class="eael-feature-list-items square stacked eael-feature-list-vertical"> <li class="eael-feature-list-item elementor-repeater-item-a705bfc"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-0"href="http://www.chim.it/sites/default/files/chimind/pdf/2022_6_39_ca.pdf" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="http://www.chim.it/sites/default/files/chimind/pdf/2022_6_39_ca.pdf" target="_blank">PROTAC (PROteolysis TArgeting Chimera)</a></h4> <p class="eael-feature-list-content">Mirizzi D <br> <em>Chimica e Farmaceutica (2022), 6, 39-43</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-3394ca3"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-1"href="http://www.chim.it/sites/default/files/chimind/pdf/2022_6_34_ca.pdf" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="http://www.chim.it/sites/default/files/chimind/pdf/2022_6_34_ca.pdf" target="_blank">Molecular glues: un diverso approccio in drug discovery</a></h4> <p class="eael-feature-list-content">Picconi P <br> <em>Chimica e Farmaceutica (2022), 6, 34-38</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-f1b9087"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-2"href="http://www.chim.it/sites/default/files/chimind/pdf/2022_5_48_ca.pdf" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="http://www.chim.it/sites/default/files/chimind/pdf/2022_5_48_ca.pdf" target="_blank">Prossimità chimicamente indotta </a></h4> <p class="eael-feature-list-content">Mirizzi D <br> <em>Chimica e Farmaceutica (2022), 5, 48-52</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-6c06de2"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-3"href="https://www.sciencedirect.com/science/article/abs/pii/S0040403922004166" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.sciencedirect.com/science/article/abs/pii/S0040403922004166" target="_blank"> Use of acridinium-based photocatalyst in the Giese-type coupling of arylboronic acids with electron poor olefins </a></h4> <p class="eael-feature-list-content">Caldarelli M, Loriz L, Piazza L, Caputo G, DeAmici M, Papeo G <br> <em>Tetrahedron Letters (2022) 103, 153978</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-a0d4cc8"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-4"href="https://onlinelibrary.wiley.com/doi/abs/10.1002/chir.23501" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/chir.23501" target="_blank"> Stereoselective synthesis of 3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives as PIM kinase inhibitors inspired from marine alkaloids</a></h4> <p class="eael-feature-list-content">Casuscelli F, Ardini E, Avanzi N, Badari A, Casale E, Disingrini T, Donati D, Ermoli A, Felder E, Galvani A, Isacchi A, Menichincheri M, Montemartini M, Orrenius C, Piutti C, Salom B, Papeo G <br> <em>Chirality (2022), 34(11), 1437-1452 </em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-27acc6e"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-5"href="https://www.isct-cytotherapy.org/article/S1465-3249(21)00749-0/fulltext" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.isct-cytotherapy.org/article/S1465-3249(21)00749-0/fulltext" target="_blank">BL-01, an Fc-bearing, tetravalent CD20 × CD5 bispecific antibody, redirects multiple immune cells to kill tumors in vitro and in vivo </a></h4> <p class="eael-feature-list-content">Interdonato A, Choblet S, Sana M, Valgardsdottir R, Cribioli S, Alzani R, Roth M, Duonor-Cerutti M, Golay J <br> <em>Cytotherapy (2022), 24(2), 161-171</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-c5d4978"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-6"href="https://www.sciencedirect.com/science/article/pii/S0959804922001708" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.sciencedirect.com/science/article/pii/S0959804922001708" target="_blank">First-in-man, first-in-class phase I study with the monopolar spindle 1 kinase inhibitor S81694 administered intravenously in adult patients with advanced, metastatic solid tumours </a></h4> <p class="eael-feature-list-content">Schöffski P, Awada A, de la Bigne A, Felloussi Z, Burbridge M, Cantero F, Colombo R, Maruzzelli S, Ammattatelli K, de Jonge M, Aftimos P, Dumez H, Sleijfer S <br> <em>Eur J Cancer (2022), 169 (135-145)</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-92d48e6"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-7"href="https://www.nature.com/articles/s41467-022-29358-6" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.nature.com/articles/s41467-022-29358-6" target="_blank">A single-cell analysis of breast cancer cell lines to study tumour heterogeneity and drug response </a></h4> <p class="eael-feature-list-content">Gambardella G, Viscido G, Tumaini B, Isacchi A, Bosotti R, di Bernardo D <br> <em>Nat Commun (2022), 13(1), 1714</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-967d4eb"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-8"href="https://link.springer.com/article/10.1007/s10120-022-01292-y" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://link.springer.com/article/10.1007/s10120-022-01292-y" target="_blank"> A randomized phase III study of fractionated docetaxel, oxaliplatin, capecitabine (low-tox) vs epirubicin, oxaliplatin and capecitabine (eox) in patients with locally advanced unresectable or metastatic gastric cancer: the lega trial </a></h4> <p class="eael-feature-list-content">Rosati G, Cella CA, Cavanna L, Codecà C, Prisciandaro M, Mosconi S, Luchena G, Silvestris N, Bernardini I, Casaretti R, Zoratto F, Amoroso D, Ciarlo A, Barni S, Cascinu S, Davite C, Di Sanzo A, Casolaro A, Bilancia D, Labianca R <br> <em>Gastric Cancer (2022), 25, 783–793 </em></p> </div> </li> </ul> </div> </div> </div> <div class="elementor-element elementor-element-f5fbb79 elementor-widget elementor-widget-heading" data-id="f5fbb79" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h4 class="elementor-heading-title elementor-size-default">Posters</h4> </div> </div> <div class="elementor-element elementor-element-c573ada elementor-widget elementor-widget-eael-feature-list" data-id="c573ada" data-element_type="widget" data-widget_type="eael-feature-list.default"> <div class="elementor-widget-container"> <div class="-icon-position-left -tablet-icon-position-left -mobile-icon-position-left"> <ul id="eael-feature-list-c573ada" class="eael-feature-list-items square stacked eael-feature-list-vertical"> <li class="eael-feature-list-item elementor-repeater-item-a705bfc"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <span class="eael-feature-list-icon fl-icon-0"> <svg aria-hidden="true" class="e-font-icon-svg e-fas-file-powerpoint" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M193.7 271.2c8.8 0 15.5 2.7 20.3 8.1 9.6 10.9 9.8 32.7-.2 44.1-4.9 5.6-11.9 8.5-21.1 8.5h-26.9v-60.7h27.9zM377 105L279 7c-4.5-4.5-10.6-7-17-7h-6v128h128v-6.1c0-6.3-2.5-12.4-7-16.9zm-153 31V0H24C10.7 0 0 10.7 0 24v464c0 13.3 10.7 24 24 24h336c13.3 0 24-10.7 24-24V160H248c-13.2 0-24-10.8-24-24zm53 165.2c0 90.3-88.8 77.6-111.1 77.6V436c0 6.6-5.4 12-12 12h-30.8c-6.6 0-12-5.4-12-12V236.2c0-6.6 5.4-12 12-12h81c44.5 0 72.9 32.8 72.9 77z"></path></svg> </span> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title">NMS-173, a potent, covalent second generation IDH1/IDH2 inhibitor </h4> <p class="eael-feature-list-content">Magnaghi P., Casuscelli F., Ardini E., Parazzoli A., Troiani S., Valsasina B., Texido G., Casale <br> E., Avanzi N., Orsini P., Nuvoloni S., Salom B., Lombardi Borgia A., Salsi E., Saturno G., Re <br> Depaolini S., Stellato C., Montagnoli A., Galvani A. and Isacchi A. <br> 34th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics; <br> October 26 - 28 2022; Barcelona, Spain<br> <a href="https://www.ejcancer.com/article/S0959-8049(22)00847-4/abstract%5d" target="blank">Abstract </a> <br> <em>European Journal of Cancer, Volume 174, S17 </em> </p> </div> </li> </ul> </div> </div> </div> </div> </details> <details id="e-n-accordion-item-1723" class="e-n-accordion-item" > <summary class="e-n-accordion-item-title" data-accordion-index="4" tabindex="-1" aria-expanded="false" aria-controls="e-n-accordion-item-1723" > <span class='e-n-accordion-item-title-header'><div class="e-n-accordion-item-title-text"> 2021 </div></span> <span class='e-n-accordion-item-title-icon'> <span class='e-opened' ><svg aria-hidden="true" class="e-font-icon-svg e-fas-minus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> <span class='e-closed'><svg aria-hidden="true" class="e-font-icon-svg e-fas-plus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> </span> </summary> <div role="region" aria-labelledby="e-n-accordion-item-1723" class="elementor-element elementor-element-04b4f86 e-con-full e-flex e-con e-child" data-id="04b4f86" data-element_type="container"> <div class="elementor-element elementor-element-81fd3ae elementor-widget elementor-widget-eael-feature-list" data-id="81fd3ae" data-element_type="widget" data-widget_type="eael-feature-list.default"> <div class="elementor-widget-container"> <div class="-icon-position-left -tablet-icon-position-left -mobile-icon-position-left"> <ul id="eael-feature-list-81fd3ae" class="eael-feature-list-items square stacked eael-feature-list-vertical"> <li class="eael-feature-list-item elementor-repeater-item-a705bfc"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-0"href="https://pubs.acs.org/doi/full/10.1021/acsabm.1c00724" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://pubs.acs.org/doi/full/10.1021/acsabm.1c00724" target="_blank">Development of an Effective Tumor-Targeted Contrast Agent for Magnetic Resonance Imaging Based on Mn/H-Ferritin Nanocomplexes </a></h4> <p class="eael-feature-list-content">Tullio C, Salvioni L, Bellini M, Degrassi A, Fiandra L, D’Arienzo M, Garbujo S, Rotem R, Testa F, Prosperi D, Colombo M <br> <em>ACS Appl Bio Mater (2021), 15, 4(11), 7800-7810</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-f80a577"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-1"href="https://onlinelibrary.wiley.com/doi/abs/10.1002/hon.2822" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/hon.2822" target="_blank">A phase II trial of bendamustine in combination with ofatumumab in patients with relapsed or refractory marginal zone B-cell lymphomas</a></h4> <p class="eael-feature-list-content">Vannata B, Vanazzi A, Negri M, Liptrott SJ, Bartosek A , Miani M , Di Sanzo A, Cavalli F, Zucca E, Stathis A <br> <em>Hematol Oncol (2021), 39(1), 60-65. </em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-3be3c85"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-2"href="https://pubs.acs.org/doi/full/10.1021/acsabm.1c00724" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://pubs.acs.org/doi/full/10.1021/acsabm.1c00724" target="_blank">Development of an Effective Tumor-Targeted Contrast Agent for Magnetic Resonance Imaging Based on Mn/H-Ferritin Nanocomplexes</a></h4> <p class="eael-feature-list-content">Tullio C, Salvioni L, Bellini M, Degrassi A, Fiandra L, D’Arienzo M, Garbujo S, Rotem R, Testa F, Prosperi D, Colombo M <br> <em>ACS Appl Bio Mater (2021), 15, 4(11), 7800-7810</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-ff64da7"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-3"href="https://haematologica.org/article/view/9675" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://haematologica.org/article/view/9675" target="_blank">The Coup-TFII orphan nuclear receptor is an activator of the γ-globin gene </a></h4> <p class="eael-feature-list-content">Fugazza C, Barbarani G, Elangovan S, Marini MG, Giolitto S, Font-Monclus I, Marongiu MF, Manunza L, Strouboulis J, Cantù C, Gasparri F, Barabino SML, Nakamura Y, Ottolenghi S, Moi P, Ronchi AE. <br> <em>Haematologica (2021), 106(2), 474-482</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-fab7f27"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-4"href="https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-021-04211-7" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-021-04211-7" target="_blank">RNAdetector: a free user-friendly stand-alone and cloud-based system for RNA-Seq data analysis </a></h4> <p class="eael-feature-list-content">La Ferlita A, Alaimo S, Di Bella S, Martorana E, Laliotis G, Bertoni F, Cascione L, Tsichlis P, Ferro A, Bosotti R, Pulvirenti A <br> <em>BMC Bioinformatics (2021), volume 22, Article number: 298</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-efcc4bd"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-5"href="https://www.mdpi.com/1999-4923/13/4/483" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.mdpi.com/1999-4923/13/4/483" target="_blank">EV20/NMS-P945, a Novel Thienoindole Based Antibody-Drug Conjugate Targeting HER-3 for Solid Tumors </a></h4> <p class="eael-feature-list-content">Capone E, Lattanzio R, Gasparri F, Orsini P, Rossi C, Iacobelli V, De Laurenzi V, Natali PG, Valsasina B, Iacobelli S, Sala GL <br> <em>Pharmaceutics (2021), 13(4), 483</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-50b7808"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-6"href="https://www.sciencedirect.com/science/article/abs/pii/S0960894X21005370?via%3Dihub" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.sciencedirect.com/science/article/abs/pii/S0960894X21005370?via%3Dihub" target="_blank">Identification of unprecedented ATP-competitive choline kinase inhibitors</a></h4> <p class="eael-feature-list-content">Quartieri F, Nesi M, Avanzi N, Borghi D, Casale E, Corti E, Cucchi U, Donati D, Fasolini M, Felder E, Galvani A, Giorgini ML, Lomolino A, Menichincheri M, Orrenius C, Perrera C, Re Depaolini S, Riccardi-Sirtori F, Salsi E, Isacchi A, Gnocchi P <br> <em>Bioorg Med Chem Lett (2021), 51, 128310</em></p> </div> </li> </ul> </div> </div> </div> </div> </details> <details id="e-n-accordion-item-1724" class="e-n-accordion-item" > <summary class="e-n-accordion-item-title" data-accordion-index="5" tabindex="-1" aria-expanded="false" aria-controls="e-n-accordion-item-1724" > <span class='e-n-accordion-item-title-header'><div class="e-n-accordion-item-title-text"> 2020 </div></span> <span class='e-n-accordion-item-title-icon'> <span class='e-opened' ><svg aria-hidden="true" class="e-font-icon-svg e-fas-minus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> <span class='e-closed'><svg aria-hidden="true" class="e-font-icon-svg e-fas-plus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> </span> </summary> <div role="region" aria-labelledby="e-n-accordion-item-1724" class="elementor-element elementor-element-82b23dc e-con-full e-flex e-con e-child" data-id="82b23dc" data-element_type="container"> <div class="elementor-element elementor-element-43f9248 elementor-widget elementor-widget-eael-feature-list" data-id="43f9248" data-element_type="widget" data-widget_type="eael-feature-list.default"> <div class="elementor-widget-container"> <div class="-icon-position-left -tablet-icon-position-left -mobile-icon-position-left"> <ul id="eael-feature-list-43f9248" class="eael-feature-list-items square stacked eael-feature-list-vertical"> <li class="eael-feature-list-item elementor-repeater-item-a705bfc"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-0"href="https://academic.oup.com/bib/article-lookup/doi/10.1093/bib/bbz110" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://academic.oup.com/bib/article-lookup/doi/10.1093/bib/bbz110" target="_blank">A benchmarking of pipelines for detecting ncRNAs from RNA-Seq data</a></h4> <p class="eael-feature-list-content">Di Bella S, La Ferlita A, Carapezza G, Alaimo S, Isacchi A, Ferro A, Pulvirenti A, Bosotti R. <br> Brief Bioinform.<em> 2020 Dec 1;21(6):1987-1998. doi: 10.1093/bib/bbz110. PMID: 31740918 </em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-9682171"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-1"href="https://www.nature.com/articles/s41597-020-00761-2" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.nature.com/articles/s41597-020-00761-2" target="_blank"> Mining potentially actionable kinase gene fusions in cancer cell lines with the KuNG FU database </a></h4> <p class="eael-feature-list-content">Somaschini A, Di Bella S, Cusi C, Raddrizzani L, Leone A, Carapezza G, Mazza T, Isacchi A, Bosotti R. <br>Sci Data. <em>2020 Nov 30;7(1):420. doi: 10.1038/s41597-020-00761-2. PMID: 33257674; PMCID: PMC7705673.</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-0400092"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-2"href="https://onlinelibrary.wiley.com/doi/abs/10.1002/hon.2822" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/hon.2822" target="_blank">A phase II trial of bendamustine in combination with ofatumumab in patients with relapsed or refractory marginal zone B-cell lymphomas </a></h4> <p class="eael-feature-list-content">Vannata B, Vanazzi A, Negri M, Liptrott SJ, Bartosek AA, Miani M, Di Sanzo A, Cavalli F, Zucca E, Stathis A. <br> <em>Hematol Oncol. 2020 Oct 26. doi: 10.1002/hon.2822. Epub ahead of print. PMID: 33103778. </em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-5c292f9"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-3"href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481078/" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7481078/" target="_blank"> Entrectinib approval by EMA reinforces options for ROS1 and tumour agnostic NTRK targeted cancer therapies </a></h4> <p class="eael-feature-list-content">Ardini E, Siena S. <br> <em>ESMO Open. 2020 Sep;5(5):e000867. doi: 10.1136/esmoopen-2020-000867. PMID: 32907817; PMCID:PMC7481078. </em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-8ce389a"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-4"href="https://ashpublications.org/blood/article/136/19/2237/460734/Increased-tumor-burden-in-patients-with-chronic" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://ashpublications.org/blood/article/136/19/2237/460734/Increased-tumor-burden-in-patients-with-chronic" target="_blank">Increased tumor burden in patients with chronic myeloid leukemia after 36 months of imatinib discontinuation </a></h4> <p class="eael-feature-list-content">Diral E, Mori S, Antolini L, Abruzzese E, Le Coutre P, Martino B, Pungolino E, Elena C, Bergamaschi M, Assouline S, Di Bona E, Gozzini A, Andrade-Campos M, Stagno F, Iurlo A, Pirola A, Fontana D, Petiti J, Bonanomi ML, Crivori P, Piazza R, Fava C, Gambacorti-Passerini C.<br> <em>Blood. 2020 Nov 5;136(19):2237-2240. doi: 10.1182/blood.2019004371. PMID: 32518953. </em></p> </div> </li> </ul> </div> </div> </div> </div> </details> <details id="e-n-accordion-item-1725" class="e-n-accordion-item" > <summary class="e-n-accordion-item-title" data-accordion-index="6" tabindex="-1" aria-expanded="false" aria-controls="e-n-accordion-item-1725" > <span class='e-n-accordion-item-title-header'><div class="e-n-accordion-item-title-text"> 2019 </div></span> <span class='e-n-accordion-item-title-icon'> <span class='e-opened' ><svg aria-hidden="true" class="e-font-icon-svg e-fas-minus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> <span class='e-closed'><svg aria-hidden="true" class="e-font-icon-svg e-fas-plus" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z"></path></svg></span> </span> </summary> <div role="region" aria-labelledby="e-n-accordion-item-1725" class="elementor-element elementor-element-e4c0564 e-con-full e-flex e-con e-child" data-id="e4c0564" data-element_type="container"> <div class="elementor-element elementor-element-431ebdc elementor-widget elementor-widget-eael-feature-list" data-id="431ebdc" data-element_type="widget" data-widget_type="eael-feature-list.default"> <div class="elementor-widget-container"> <div class="-icon-position-left -tablet-icon-position-left -mobile-icon-position-left"> <ul id="eael-feature-list-431ebdc" class="eael-feature-list-items square stacked eael-feature-list-vertical"> <li class="eael-feature-list-item elementor-repeater-item-a705bfc"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-0"href="https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5676-3" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5676-3" target="_blank">Comprehensive kinome NGS targeted expression profiling by KING-REX </a></h4> <p class="eael-feature-list-content">Carapezza G, Cusi C, Rizzo E, Raddrizzani L, Di Bella S, Somaschini A, Leone A, Lupi R, Mutarelli M, Nigro V, di Bernardo D, Magni P, Isacchi A, Bosotti R<br> <em>BMC Genomics (2019), 20(1), 307</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-271e678"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-1"href="https://pubs.acs.org/doi/10.1021/acsmedchemlett.8b00569" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://pubs.acs.org/doi/10.1021/acsmedchemlett.8b00569" target="_blank">Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515 </a></h4> <p class="eael-feature-list-content">G. Papeo, P. Orsini, N. Avanzi, D. Borghi, E. Casale, M. Ciomei, A. Cirla, V. Desperati, D. Donati, E. R. Felder, A. Galvani, M. Guanci, A. Isacchi, H. Posteri, S. Rainoldi, Federico Riccardi-Sirtori,§ Alessandra Scolaro,∥and Alessia Montagnoli <br> <em>ACS Medicinal Chemistry Letters 2019</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-5a86bc1"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-2"href="https://www.science.org/doi/10.1126/scitranslmed.aau9732" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.science.org/doi/10.1126/scitranslmed.aau9732" target="_blank">An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma</a></h4> <p class="eael-feature-list-content">Sano R, Krytska K, Larmour CE, Raman P, Martinez D, Ligon GF, Lillquist JS, Cucchi U, Orsini P, Rizzi S, Pawel BR, Alvarado D, Mossé YP <br> <em>Sci Transl Med (2019), 11(483) </em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-a481d45"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-3"href="https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.201805447" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.201805447" target="_blank">Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin Targeted Conjugate </a></h4> <p class="eael-feature-list-content">Raposo Moreira Dias A, Pina A, Dean A, Lerchen HG, Caruso M, Gasparri F, Fraietta I, Troiani S, Arosio D, Belvisi L, Pignataro L, Dal Corso A, Gennari C <br> <em>Chemistry (2019), 25(7), 1696-1700</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-9403dba"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-4"href="https://academic.oup.com/bib/article/21/6/1987/5618829" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://academic.oup.com/bib/article/21/6/1987/5618829" target="_blank">A benchmarking of pipelines for detecting ncRNAs from RNA-Seq data</a></h4> <p class="eael-feature-list-content">Di Bella S, La Ferlita A, Carapezza G, Alaimo S, Isacchi A, Ferro A, Pulvirenti A, Bosotti R. <br> <em>Brief Bioinform (2019), Nov 18 [Epub ahead of print]</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-1a2b44c"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-5"href="https://link.springer.com/protocol/10.1007/978-1-4939-9207-2_14" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://link.springer.com/protocol/10.1007/978-1-4939-9207-2_14" target="_blank">Investigating miRNA-IncRNA interactions: Computational tools and resources </a></h4> <p class="eael-feature-list-content">Veneziano D, Marceca GP, Di Bella S, Nigita G, Distefano R, Croce CM <br> <em>Methods Mol Biol (2019), 1970 (Chapt 14), 251-277</em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-e41f580"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-6"href="https://pubs.acs.org/doi/10.1021/acs.biomac.9b00148" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://pubs.acs.org/doi/10.1021/acs.biomac.9b00148" target="_blank">Drug-Initiated synthesis of Heterotelechelic Polymer Prodrug Nanoparticles for in vivo imaging and cancer cell targeting </a></h4> <p class="eael-feature-list-content">Vinciguerra D, Degrassi A, Mancini L, Mura S, Mougin J, Couvreur P, Nicolas J <br> <em>Biomacromolecules (2019), 20(7), 2464-2476 </em></p> </div> </li> <li class="eael-feature-list-item elementor-repeater-item-9da6379"> <div class="eael-feature-list-icon-box"> <div class="eael-feature-list-icon-inner"> <a class="eael-feature-list-icon fl-icon-7"href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769691/" target="_blank"> <svg aria-hidden="true" class="e-font-icon-svg e-far-file-alt" viewBox="0 0 384 512" xmlns="http://www.w3.org/2000/svg"><path d="M288 248v28c0 6.6-5.4 12-12 12H108c-6.6 0-12-5.4-12-12v-28c0-6.6 5.4-12 12-12h168c6.6 0 12 5.4 12 12zm-12 72H108c-6.6 0-12 5.4-12 12v28c0 6.6 5.4 12 12 12h168c6.6 0 12-5.4 12-12v-28c0-6.6-5.4-12-12-12zm108-188.1V464c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V48C0 21.5 21.5 0 48 0h204.1C264.8 0 277 5.1 286 14.1L369.9 98c9 8.9 14.1 21.2 14.1 33.9zm-128-80V128h76.1L256 51.9zM336 464V176H232c-13.3 0-24-10.7-24-24V48H48v416h288z"></path></svg> </a> </div> </div> <div class="eael-feature-list-content-box"> <h4 class="eael-feature-list-title"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769691/" target="_blank">Mechanism of action of the tumor vessel targeting agent NGR-hTNF: Role of both NGR peptide and hTNF in cell binding and signaling </a></h4> <p class="eael-feature-list-content">Valentinis B, Porcellini S, Asperti C, Cota M, Zhou D, Di Matteo P, Garau G, Zucchelli C, Avanzi NR, Rizzardi GP, Degano M, Musco G, Traversari C <br> <em>Int J Mol Sci (2019), 20(18), 4511-4533 </em></p> </div> </li> </ul> </div> </div> </div> </div> </details> </div> </div> </div> </div> </div> </div> </div> </main> <div data-elementor-type="footer" data-elementor-id="216" class="elementor elementor-216 elementor-location-footer" data-elementor-post-type="elementor_library"> <div class="elementor-element elementor-element-cc49d6a e-flex e-con-boxed e-con e-parent" data-id="cc49d6a" data-element_type="container" data-settings="{"background_background":"gradient"}"> <div class="e-con-inner"> </div> </div> <div class="elementor-element elementor-element-3aed4b8 footer-main e-con-full e-flex e-con e-parent" data-id="3aed4b8" data-element_type="container" data-settings="{"background_background":"classic"}"> <div class="elementor-element elementor-element-8fab09c e-con-full e-flex e-con e-child" data-id="8fab09c" data-element_type="container"> <div class="elementor-element elementor-element-31fb7a7 elementor-widget elementor-widget-image" data-id="31fb7a7" data-element_type="widget" data-widget_type="image.default"> <div class="elementor-widget-container"> <a href="https://www.nervianoms.com" target="_blank"> <img width="2053" height="1063" src="https://www.nervianoms.com/wp-content/uploads/2024/10/NMS-group-logo-1.png" class="attachment-full size-full wp-image-446" alt="Nerviano MS Logo" srcset="https://www.nervianoms.com/wp-content/uploads/2024/10/NMS-group-logo-1.png 2053w, https://www.nervianoms.com/wp-content/uploads/2024/10/NMS-group-logo-1-300x155.png 300w, https://www.nervianoms.com/wp-content/uploads/2024/10/NMS-group-logo-1-1024x530.png 1024w, https://www.nervianoms.com/wp-content/uploads/2024/10/NMS-group-logo-1-768x398.png 768w, https://www.nervianoms.com/wp-content/uploads/2024/10/NMS-group-logo-1-1536x795.png 1536w, https://www.nervianoms.com/wp-content/uploads/2024/10/NMS-group-logo-1-2048x1060.png 2048w" sizes="(max-width: 2053px) 100vw, 2053px" /> </a> </div> </div> </div> <div class="elementor-element elementor-element-d63ddb4 e-con-full e-flex e-con e-child" data-id="d63ddb4" data-element_type="container"> <a class="eael-wrapper-link-e80c598 --eael-wrapper-link-tag" href="https://www.linkedin.com/company/nerviano-medical-sciences-s.r.l./" target="_blank"></a> <div data-eael-wrapper-link="eael-wrapper-link-e80c598" class="elementor-element elementor-element-e80c598 elementor-position-right elementor-mobile-position-right elementor-widget-mobile__width-initial elementor-view-default elementor-vertical-align-top elementor-widget elementor-widget-icon-box" data-id="e80c598" data-element_type="widget" data-widget_type="icon-box.default"> <div class="elementor-widget-container"> <div class="elementor-icon-box-wrapper"> <div class="elementor-icon-box-icon"> <a href="https://www.linkedin.com/company/nerviano-medical-sciences-s.r.l./" target="_blank" class="elementor-icon elementor-animation-" tabindex="-1"> <svg aria-hidden="true" class="e-font-icon-svg e-fab-linkedin" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z"></path></svg> </a> </div> <div class="elementor-icon-box-content"> <p class="elementor-icon-box-description"> Follow Us on </p> </div> </div> </div> </div> </div> <div class="elementor-element elementor-element-a8aadfe e-con-full e-flex e-con e-child" data-id="a8aadfe" data-element_type="container"> <div class="elementor-element elementor-element-1b6cd66 elementor-widget elementor-widget-text-editor" data-id="1b6cd66" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <p><strong data-renderer-mark="true">Nerviano Medical Sciences S.r.l. </strong></p><p>Viale Luigi Pasteur 10<br />20014 Nerviano (MI)<br />Italy</p><p>Share Capital: € 1,200,000.00<br />fully paid-in</p><p>Company subject to the management and coordination of NMS Group S.p.A.</p> </div> </div> </div> <div class="elementor-element elementor-element-2f17765 e-con-full e-flex e-con e-child" data-id="2f17765" data-element_type="container"> <div class="elementor-element elementor-element-98728d9 elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu" data-id="98728d9" data-element_type="widget" data-settings="{"layout":"vertical","submenu_icon":{"value":"<svg class=\"e-font-icon-svg e-fas-caret-down\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\"><\/path><\/svg>","library":"fa-solid"}}" data-widget_type="nav-menu.default"> <div class="elementor-widget-container"> <nav aria-label="Menu" class="elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none"> <ul id="menu-1-98728d9" class="elementor-nav-menu sm-vertical"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-221"><a href="https://www.nervianoms.com/about-us/" class="elementor-item">About Us</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1407"><a href="/about-us/#history" class="elementor-item elementor-item-anchor">History</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1408"><a href="/about-us/#leadership" class="elementor-item elementor-item-anchor">Leadership</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1409"><a href="/about-us/#scientific-advisory-board" class="elementor-item elementor-item-anchor">Scientific Advisory Board</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1410"><a href="/about-us/#collaboration-and-partnership" class="elementor-item elementor-item-anchor">Collaboration and Partnership</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1411"><a href="/about-us/#locations" class="elementor-item elementor-item-anchor">Locations</a></li> </ul> </nav> <nav class="elementor-nav-menu--dropdown elementor-nav-menu__container" aria-hidden="true"> <ul id="menu-2-98728d9" class="elementor-nav-menu sm-vertical"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-221"><a href="https://www.nervianoms.com/about-us/" class="elementor-item" tabindex="-1">About Us</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1407"><a href="/about-us/#history" class="elementor-item elementor-item-anchor" tabindex="-1">History</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1408"><a href="/about-us/#leadership" class="elementor-item elementor-item-anchor" tabindex="-1">Leadership</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1409"><a href="/about-us/#scientific-advisory-board" class="elementor-item elementor-item-anchor" tabindex="-1">Scientific Advisory Board</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1410"><a href="/about-us/#collaboration-and-partnership" class="elementor-item elementor-item-anchor" tabindex="-1">Collaboration and Partnership</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1411"><a href="/about-us/#locations" class="elementor-item elementor-item-anchor" tabindex="-1">Locations</a></li> </ul> </nav> </div> </div> </div> <div class="elementor-element elementor-element-365ef5b e-con-full e-flex e-con e-child" data-id="365ef5b" data-element_type="container"> <div class="elementor-element elementor-element-25065c1 elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu" data-id="25065c1" data-element_type="widget" data-settings="{"layout":"vertical","submenu_icon":{"value":"<svg class=\"e-font-icon-svg e-fas-caret-down\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\"><\/path><\/svg>","library":"fa-solid"}}" data-widget_type="nav-menu.default"> <div class="elementor-widget-container"> <nav aria-label="Menu" class="elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none"> <ul id="menu-1-25065c1" class="elementor-nav-menu sm-vertical"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-227"><a href="https://www.nervianoms.com/our-science/" class="elementor-item">Our Science</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1412"><a href="/our-science/#small-molecules" class="elementor-item elementor-item-anchor">Small Molecules</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1413"><a href="/our-science/#adc-platform" class="elementor-item elementor-item-anchor">ADC Platform</a></li> </ul> </nav> <nav class="elementor-nav-menu--dropdown elementor-nav-menu__container" aria-hidden="true"> <ul id="menu-2-25065c1" class="elementor-nav-menu sm-vertical"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-227"><a href="https://www.nervianoms.com/our-science/" class="elementor-item" tabindex="-1">Our Science</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1412"><a href="/our-science/#small-molecules" class="elementor-item elementor-item-anchor" tabindex="-1">Small Molecules</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1413"><a href="/our-science/#adc-platform" class="elementor-item elementor-item-anchor" tabindex="-1">ADC Platform</a></li> </ul> </nav> </div> </div> <div class="elementor-element elementor-element-066e053 elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu" data-id="066e053" data-element_type="widget" data-settings="{"layout":"vertical","submenu_icon":{"value":"<svg class=\"e-font-icon-svg e-fas-caret-down\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\"><\/path><\/svg>","library":"fa-solid"}}" data-widget_type="nav-menu.default"> <div class="elementor-widget-container"> <nav aria-label="Menu" class="elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none"> <ul id="menu-1-066e053" class="elementor-nav-menu sm-vertical"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-233"><a href="https://www.nervianoms.com/pipeline/" class="elementor-item">Pipeline</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-234"><a href="https://www.nervianoms.com/careers/" class="elementor-item">Careers</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-235"><a href="https://www.nervianoms.com/contact-us/" class="elementor-item">Contact Us</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-236"><a href="https://www.nervianoms.com/sitemap/" class="elementor-item">Sitemap</a></li> </ul> </nav> <nav class="elementor-nav-menu--dropdown elementor-nav-menu__container" aria-hidden="true"> <ul id="menu-2-066e053" class="elementor-nav-menu sm-vertical"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-233"><a href="https://www.nervianoms.com/pipeline/" class="elementor-item" tabindex="-1">Pipeline</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-234"><a href="https://www.nervianoms.com/careers/" class="elementor-item" tabindex="-1">Careers</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-235"><a href="https://www.nervianoms.com/contact-us/" class="elementor-item" tabindex="-1">Contact Us</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-236"><a href="https://www.nervianoms.com/sitemap/" class="elementor-item" tabindex="-1">Sitemap</a></li> </ul> </nav> </div> </div> </div> <div class="elementor-element elementor-element-dc57e37 e-con-full e-flex e-con e-child" data-id="dc57e37" data-element_type="container"> <div class="elementor-element elementor-element-92f8a55 elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu" data-id="92f8a55" data-element_type="widget" data-settings="{"layout":"vertical","submenu_icon":{"value":"<svg class=\"e-font-icon-svg e-fas-caret-down\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\"><\/path><\/svg>","library":"fa-solid"}}" data-widget_type="nav-menu.default"> <div class="elementor-widget-container"> <nav aria-label="Menu" class="elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none"> <ul id="menu-1-92f8a55" class="elementor-nav-menu sm-vertical"><li class="menu-item menu-item-type-post_type menu-item-object-page current-menu-item page_item page-item-42 current_page_item menu-item-230"><a href="https://www.nervianoms.com/news-events-publications/" aria-current="page" class="elementor-item elementor-item-active">News/Events & Publications</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4616"><a href="https://www.nervianoms.com/news-events-publications/#news" aria-current="page" class="elementor-item elementor-item-anchor">News</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4617"><a href="https://www.nervianoms.com/news-events-publications/#events" aria-current="page" class="elementor-item elementor-item-anchor">Events</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4618"><a href="https://www.nervianoms.com/news-events-publications/#publications" aria-current="page" class="elementor-item elementor-item-anchor">Publications</a></li> </ul> </nav> <nav class="elementor-nav-menu--dropdown elementor-nav-menu__container" aria-hidden="true"> <ul id="menu-2-92f8a55" class="elementor-nav-menu sm-vertical"><li class="menu-item menu-item-type-post_type menu-item-object-page current-menu-item page_item page-item-42 current_page_item menu-item-230"><a href="https://www.nervianoms.com/news-events-publications/" aria-current="page" class="elementor-item elementor-item-active" tabindex="-1">News/Events & Publications</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4616"><a href="https://www.nervianoms.com/news-events-publications/#news" aria-current="page" class="elementor-item elementor-item-anchor" tabindex="-1">News</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4617"><a href="https://www.nervianoms.com/news-events-publications/#events" aria-current="page" class="elementor-item elementor-item-anchor" tabindex="-1">Events</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom current-menu-item menu-item-4618"><a href="https://www.nervianoms.com/news-events-publications/#publications" aria-current="page" class="elementor-item elementor-item-anchor" tabindex="-1">Publications</a></li> </ul> </nav> </div> </div> </div> <div class="elementor-element elementor-element-0b47339 e-con-full bottom-menu e-flex e-con e-child" data-id="0b47339" data-element_type="container"> <div class="elementor-element elementor-element-dab8764 footer-links elementor-nav-menu__align-start elementor-nav-menu--dropdown-none elementor-widget-mobile__width-inherit elementor-widget elementor-widget-nav-menu" data-id="dab8764" data-element_type="widget" data-settings="{"layout":"horizontal","submenu_icon":{"value":"<svg class=\"e-font-icon-svg e-fas-caret-down\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\"><\/path><\/svg>","library":"fa-solid"}}" data-widget_type="nav-menu.default"> <div class="elementor-widget-container"> <nav aria-label="Menu" class="elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-horizontal e--pointer-none"> <ul id="menu-1-dab8764" class="elementor-nav-menu"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-241"><a href="https://www.nervianoms.com/governance-and-compliance/" class="elementor-item">Governance and Compliance</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-240"><a href="https://www.nervianoms.com/privacy-policy/" class="elementor-item">Privacy Policy</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-239"><a href="https://www.nervianoms.com/cookie-policy/" class="elementor-item">Cookie Policy</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-238"><a href="https://www.nervianoms.com/terms-and-conditions/" class="elementor-item">Terms and Conditions</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-237"><a href="https://www.nervianoms.com/msca-detrimode-project/" class="elementor-item">MSCA Detrimode Project</a></li> </ul> </nav> <nav class="elementor-nav-menu--dropdown elementor-nav-menu__container" aria-hidden="true"> <ul id="menu-2-dab8764" class="elementor-nav-menu"><li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-241"><a href="https://www.nervianoms.com/governance-and-compliance/" class="elementor-item" tabindex="-1">Governance and Compliance</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-240"><a href="https://www.nervianoms.com/privacy-policy/" class="elementor-item" tabindex="-1">Privacy Policy</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-239"><a href="https://www.nervianoms.com/cookie-policy/" class="elementor-item" tabindex="-1">Cookie Policy</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-238"><a href="https://www.nervianoms.com/terms-and-conditions/" class="elementor-item" tabindex="-1">Terms and Conditions</a></li> <li class="menu-item menu-item-type-post_type menu-item-object-page menu-item-237"><a href="https://www.nervianoms.com/msca-detrimode-project/" class="elementor-item" tabindex="-1">MSCA Detrimode Project</a></li> </ul> </nav> </div> </div> </div> <div class="elementor-element elementor-element-c1b7a27 e-con-full e-flex e-con e-child" data-id="c1b7a27" data-element_type="container"> <div class="elementor-element elementor-element-1669b08 elementor-widget elementor-widget-text-editor" data-id="1669b08" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> Copyright © 2025 Nerviano Medical Sciences S.r.l </div> </div> </div> <div class="elementor-element elementor-element-51e12df e-con-full e-flex e-con e-child" data-id="51e12df" data-element_type="container"> <div class="elementor-element elementor-element-4b08560 elementor-widget elementor-widget-text-editor" data-id="4b08560" data-element_type="widget" data-widget_type="text-editor.default"> <div class="elementor-widget-container"> <a href="https://axxiem.com/" target="_blank" rel="noopener" style="color:#fff">Website by Axxiem</a> </div> </div> </div> </div> </div> <style id="elementor-post-465">.elementor-465 .elementor-element.elementor-element-792636bd{--display:flex;--min-height:24vh;--flex-direction:column;--container-widget-width:100%;--container-widget-height:initial;--container-widget-flex-grow:0;--container-widget-align-self:initial;--flex-wrap-mobile:wrap;--justify-content:center;--gap:35px 35px;--row-gap:35px;--column-gap:35px;--padding-top:40px;--padding-bottom:40px;--padding-left:40px;--padding-right:40px;}.elementor-widget-heading .elementor-heading-title{font-family:var( --e-global-typography-primary-font-family ), Sans-serif;}.elementor-465 .elementor-element.elementor-element-634abb9c{text-align:center;}.elementor-465 .elementor-element.elementor-element-634abb9c .elementor-heading-title{color:#000000;}.elementor-465 .elementor-element.elementor-element-47153f4b{--grid-side-margin:10px;--grid-column-gap:10px;--grid-row-gap:10px;--grid-bottom-margin:10px;--e-share-buttons-primary-color:var( --e-global-color-accent );--e-share-buttons-secondary-color:#FFFFFF;}#elementor-popup-modal-465 .dialog-widget-content{animation-duration:0.5s;background-color:#FFFFFF;box-shadow:0px 0px 35px 0px rgba(0, 0, 0, 0.15);}#elementor-popup-modal-465{background-color:#000000E0;justify-content:center;align-items:center;pointer-events:all;}#elementor-popup-modal-465 .dialog-message{width:665px;height:auto;}#elementor-popup-modal-465 .dialog-close-button{display:flex;font-size:20px;}#elementor-popup-modal-465 .dialog-close-button:hover i{color:#000000;}@media(max-width:1024px){ .elementor-465 .elementor-element.elementor-element-47153f4b{--grid-side-margin:20px;--grid-column-gap:20px;--grid-row-gap:14px;--grid-bottom-margin:14px;}#elementor-popup-modal-465 .dialog-message{width:680px;}}@media(max-width:767px){.elementor-465 .elementor-element.elementor-element-792636bd{--min-height:30vh;--padding-top:0%;--padding-bottom:0%;--padding-left:5%;--padding-right:5%;} .elementor-465 .elementor-element.elementor-element-47153f4b{--grid-side-margin:20px;--grid-column-gap:20px;--grid-row-gap:14px;--grid-bottom-margin:14px;}.elementor-465 .elementor-element.elementor-element-47153f4b{--grid-side-margin:20px;--grid-column-gap:20px;--grid-row-gap:14px;--grid-bottom-margin:14px;}#elementor-popup-modal-465 .dialog-message{width:345px;}#elementor-popup-modal-465 .dialog-close-button{top:10px;}body:not(.rtl) #elementor-popup-modal-465 .dialog-close-button{right:10px;}body.rtl #elementor-popup-modal-465 .dialog-close-button{left:10px;}}</style> <div data-elementor-type="popup" data-elementor-id="465" class="elementor elementor-465 elementor-location-popup" data-elementor-settings="{"entrance_animation":"fadeIn","exit_animation":"fadeIn","entrance_animation_duration":{"unit":"px","size":0.5,"sizes":[]},"avoid_multiple_popups":"yes","a11y_navigation":"yes","timing":[]}" data-elementor-post-type="elementor_library"> <div class="elementor-element elementor-element-792636bd e-con-full e-flex e-con e-parent" data-id="792636bd" data-element_type="container"> <div class="elementor-element elementor-element-634abb9c elementor-widget elementor-widget-heading" data-id="634abb9c" data-element_type="widget" data-widget_type="heading.default"> <div class="elementor-widget-container"> <h3 class="elementor-heading-title elementor-size-default">Share this page</h3> </div> </div> <div class="elementor-element elementor-element-47153f4b elementor-share-buttons--skin-minimal elementor-share-buttons--shape-circle elementor-grid-mobile-1 elementor-share-buttons--color-custom elementor-share-buttons--view-icon-text elementor-grid-0 elementor-widget elementor-widget-share-buttons" data-id="47153f4b" data-element_type="widget" data-widget_type="share-buttons.default"> <div class="elementor-widget-container"> <div class="elementor-grid"> <div class="elementor-grid-item"> <div class="elementor-share-btn elementor-share-btn_facebook" role="button" tabindex="0" aria-label="Share on facebook" > <span class="elementor-share-btn__icon"> <svg class="e-font-icon-svg e-fab-facebook" viewBox="0 0 512 512" xmlns="http://www.w3.org/2000/svg"><path d="M504 256C504 119 393 8 256 8S8 119 8 256c0 123.78 90.69 226.38 209.25 245V327.69h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.28c-30.8 0-40.41 19.12-40.41 38.73V256h68.78l-11 71.69h-57.78V501C413.31 482.38 504 379.78 504 256z"></path></svg> </span> <div class="elementor-share-btn__text"> <span class="elementor-share-btn__title"> Facebook </span> </div> </div> </div> <div class="elementor-grid-item"> <div class="elementor-share-btn elementor-share-btn_twitter" role="button" tabindex="0" aria-label="Share on twitter" > <span class="elementor-share-btn__icon"> <svg class="e-font-icon-svg e-fab-twitter" viewBox="0 0 512 512" xmlns="http://www.w3.org/2000/svg"><path d="M459.37 151.716c.325 4.548.325 9.097.325 13.645 0 138.72-105.583 298.558-298.558 298.558-59.452 0-114.68-17.219-161.137-47.106 8.447.974 16.568 1.299 25.34 1.299 49.055 0 94.213-16.568 130.274-44.832-46.132-.975-84.792-31.188-98.112-72.772 6.498.974 12.995 1.624 19.818 1.624 9.421 0 18.843-1.3 27.614-3.573-48.081-9.747-84.143-51.98-84.143-102.985v-1.299c13.969 7.797 30.214 12.67 47.431 13.319-28.264-18.843-46.781-51.005-46.781-87.391 0-19.492 5.197-37.36 14.294-52.954 51.655 63.675 129.3 105.258 216.365 109.807-1.624-7.797-2.599-15.918-2.599-24.04 0-57.828 46.782-104.934 104.934-104.934 30.213 0 57.502 12.67 76.67 33.137 23.715-4.548 46.456-13.32 66.599-25.34-7.798 24.366-24.366 44.833-46.132 57.827 21.117-2.273 41.584-8.122 60.426-16.243-14.292 20.791-32.161 39.308-52.628 54.253z"></path></svg> </span> <div class="elementor-share-btn__text"> <span class="elementor-share-btn__title"> Twitter </span> </div> </div> </div> <div class="elementor-grid-item"> <div class="elementor-share-btn elementor-share-btn_linkedin" role="button" tabindex="0" aria-label="Share on linkedin" > <span class="elementor-share-btn__icon"> <svg class="e-font-icon-svg e-fab-linkedin" viewBox="0 0 448 512" xmlns="http://www.w3.org/2000/svg"><path d="M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z"></path></svg> </span> <div class="elementor-share-btn__text"> <span class="elementor-share-btn__title"> LinkedIn </span> </div> </div> </div> <div class="elementor-grid-item"> <div class="elementor-share-btn elementor-share-btn_email" role="button" tabindex="0" aria-label="Share on email" > <span class="elementor-share-btn__icon"> <svg class="e-font-icon-svg e-fas-envelope" viewBox="0 0 512 512" xmlns="http://www.w3.org/2000/svg"><path d="M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z"></path></svg> </span> <div class="elementor-share-btn__text"> <span class="elementor-share-btn__title"> Email </span> </div> </div> </div> </div> </div> </div> </div> </div> <script type='text/javascript'> const lazyloadRunObserver = () => { const lazyloadBackgrounds = document.querySelectorAll( `.e-con.e-parent:not(.e-lazyloaded)` ); const lazyloadBackgroundObserver = new IntersectionObserver( ( entries ) => { entries.forEach( ( entry ) => { if ( entry.isIntersecting ) { let lazyloadBackground = entry.target; if( lazyloadBackground ) { lazyloadBackground.classList.add( 'e-lazyloaded' ); } lazyloadBackgroundObserver.unobserve( entry.target ); } }); }, { rootMargin: '200px 0px 200px 0px' } ); lazyloadBackgrounds.forEach( ( lazyloadBackground ) => { lazyloadBackgroundObserver.observe( lazyloadBackground ); } ); }; const events = [ 'DOMContentLoaded', 'elementor/lazyload/observe', ]; events.forEach( ( event ) => { document.addEventListener( event, lazyloadRunObserver ); } ); </script> <script type="text/javascript" id="pf_script"> var pfHeaderImgUrl = ''; var pfHeaderTagline = ''; var pfdisableClickToDel = '1'; var pfImagesSize = 'full-size'; var pfImageDisplayStyle = 'block'; var pfEncodeImages = '0'; var pfShowHiddenContent = '1'; var pfDisableEmail = '0'; var pfDisablePDF = '0'; var pfDisablePrint = '0'; var pfPlatform = 'WordPress'; (function($){ $(document).ready(function(){ if($('.pf-button-content').length === 0){ $('style#pf-excerpt-styles').remove(); } }); })(jQuery); </script> <script defer src='https://cdn.printfriendly.com/printfriendly.js'></script> <printfriendly-css style="display: none;">svg.e-font-icon-svg {display:none!important} .elementor-button-icon {display:none!important} .show-more, .show-more2 {display:none!important} img.pf-large-image.pf-primary-img.flex-width.pf-size-full.blockImage { display: none!important; }</printfriendly-css> <link rel='stylesheet' id='eael-4855-css' href='https://www.nervianoms.com/wp-content/uploads/essential-addons-elementor/eael-4855.css?ver=1738292536' media='all' /> <link rel='stylesheet' id='widget-image-box-css' href='https://www.nervianoms.com/wp-content/uploads/elementor/css/custom-widget-image-box.min.css?ver=1738135125' media='all' /> <link rel='stylesheet' id='widget-share-buttons-css' href='https://www.nervianoms.com/wp-content/plugins/elementor-pro/assets/css/widget-share-buttons.min.css?ver=3.26.3' media='all' /> <link rel='stylesheet' id='e-apple-webkit-css' href='https://www.nervianoms.com/wp-content/uploads/elementor/css/custom-apple-webkit.min.css?ver=1738135139' media='all' /> <link rel='stylesheet' id='e-animation-fadeIn-css' href='https://www.nervianoms.com/wp-content/plugins/elementor/assets/lib/animations/styles/fadeIn.min.css?ver=3.26.4' media='all' /> <link rel='stylesheet' id='e-popup-css' href='https://www.nervianoms.com/wp-content/plugins/elementor-pro/assets/css/conditionals/popup.min.css?ver=3.26.3' media='all' /> <script id="eael-general-js-extra"> var localize = {"ajaxurl":"https:\/\/www.nervianoms.com\/wp-admin\/admin-ajax.php","nonce":"e5ab870923","i18n":{"added":"Added ","compare":"Compare","loading":"Loading..."},"eael_translate_text":{"required_text":"is a required field","invalid_text":"Invalid","billing_text":"Billing","shipping_text":"Shipping","fg_mfp_counter_text":"of"},"page_permalink":"https:\/\/www.nervianoms.com\/news-events-publications\/","cart_redirectition":"","cart_page_url":"","el_breakpoints":{"mobile":{"label":"Mobile Portrait","value":767,"default_value":767,"direction":"max","is_enabled":true},"mobile_extra":{"label":"Mobile Landscape","value":880,"default_value":880,"direction":"max","is_enabled":false},"tablet":{"label":"Tablet Portrait","value":1024,"default_value":1024,"direction":"max","is_enabled":true},"tablet_extra":{"label":"Tablet Landscape","value":1200,"default_value":1200,"direction":"max","is_enabled":false},"laptop":{"label":"Laptop","value":1366,"default_value":1366,"direction":"max","is_enabled":true},"widescreen":{"label":"Widescreen","value":1600,"default_value":2400,"direction":"min","is_enabled":true}}}; </script> <script src="https://www.nervianoms.com/wp-content/plugins/essential-addons-for-elementor-lite/assets/front-end/js/view/general.min.js?ver=6.1.0" id="eael-general-js"></script> <script src="https://www.nervianoms.com/wp-content/uploads/essential-addons-elementor/eael-216.js?ver=1738116821" id="eael-216-js"></script> <script id="rocket-browser-checker-js-after"> "use strict";var _createClass=function(){function defineProperties(target,props){for(var i=0;i<props.length;i++){var descriptor=props[i];descriptor.enumerable=descriptor.enumerable||!1,descriptor.configurable=!0,"value"in descriptor&&(descriptor.writable=!0),Object.defineProperty(target,descriptor.key,descriptor)}}return function(Constructor,protoProps,staticProps){return protoProps&&defineProperties(Constructor.prototype,protoProps),staticProps&&defineProperties(Constructor,staticProps),Constructor}}();function _classCallCheck(instance,Constructor){if(!(instance instanceof Constructor))throw new TypeError("Cannot call a class as a function")}var RocketBrowserCompatibilityChecker=function(){function RocketBrowserCompatibilityChecker(options){_classCallCheck(this,RocketBrowserCompatibilityChecker),this.passiveSupported=!1,this._checkPassiveOption(this),this.options=!!this.passiveSupported&&options}return _createClass(RocketBrowserCompatibilityChecker,[{key:"_checkPassiveOption",value:function(self){try{var options={get passive(){return!(self.passiveSupported=!0)}};window.addEventListener("test",null,options),window.removeEventListener("test",null,options)}catch(err){self.passiveSupported=!1}}},{key:"initRequestIdleCallback",value:function(){!1 in window&&(window.requestIdleCallback=function(cb){var start=Date.now();return setTimeout(function(){cb({didTimeout:!1,timeRemaining:function(){return Math.max(0,50-(Date.now()-start))}})},1)}),!1 in window&&(window.cancelIdleCallback=function(id){return clearTimeout(id)})}},{key:"isDataSaverModeOn",value:function(){return"connection"in navigator&&!0===navigator.connection.saveData}},{key:"supportsLinkPrefetch",value:function(){var elem=document.createElement("link");return elem.relList&&elem.relList.supports&&elem.relList.supports("prefetch")&&window.IntersectionObserver&&"isIntersecting"in IntersectionObserverEntry.prototype}},{key:"isSlowConnection",value:function(){return"connection"in navigator&&"effectiveType"in navigator.connection&&("2g"===navigator.connection.effectiveType||"slow-2g"===navigator.connection.effectiveType)}}]),RocketBrowserCompatibilityChecker}(); </script> <script id="rocket-preload-links-js-extra"> var RocketPreloadLinksConfig = {"excludeUris":"\/(?:.+\/)?feed(?:\/(?:.+\/?)?)?$|\/(?:.+\/)?embed\/|\/(index.php\/)?(.*)wp-json(\/.*|$)|\/refer\/|\/go\/|\/recommend\/|\/recommends\/","usesTrailingSlash":"1","imageExt":"jpg|jpeg|gif|png|tiff|bmp|webp|avif|pdf|doc|docx|xls|xlsx|php","fileExt":"jpg|jpeg|gif|png|tiff|bmp|webp|avif|pdf|doc|docx|xls|xlsx|php|html|htm","siteUrl":"https:\/\/www.nervianoms.com","onHoverDelay":"100","rateThrottle":"3"}; </script> <script id="rocket-preload-links-js-after"> (function() { "use strict";var r="function"==typeof Symbol&&"symbol"==typeof Symbol.iterator?function(e){return typeof e}:function(e){return e&&"function"==typeof Symbol&&e.constructor===Symbol&&e!==Symbol.prototype?"symbol":typeof e},e=function(){function i(e,t){for(var n=0;n<t.length;n++){var i=t[n];i.enumerable=i.enumerable||!1,i.configurable=!0,"value"in i&&(i.writable=!0),Object.defineProperty(e,i.key,i)}}return function(e,t,n){return t&&i(e.prototype,t),n&&i(e,n),e}}();function i(e,t){if(!(e instanceof t))throw new TypeError("Cannot call a class as a function")}var t=function(){function n(e,t){i(this,n),this.browser=e,this.config=t,this.options=this.browser.options,this.prefetched=new Set,this.eventTime=null,this.threshold=1111,this.numOnHover=0}return e(n,[{key:"init",value:function(){!this.browser.supportsLinkPrefetch()||this.browser.isDataSaverModeOn()||this.browser.isSlowConnection()||(this.regex={excludeUris:RegExp(this.config.excludeUris,"i"),images:RegExp(".("+this.config.imageExt+")$","i"),fileExt:RegExp(".("+this.config.fileExt+")$","i")},this._initListeners(this))}},{key:"_initListeners",value:function(e){-1<this.config.onHoverDelay&&document.addEventListener("mouseover",e.listener.bind(e),e.listenerOptions),document.addEventListener("mousedown",e.listener.bind(e),e.listenerOptions),document.addEventListener("touchstart",e.listener.bind(e),e.listenerOptions)}},{key:"listener",value:function(e){var t=e.target.closest("a"),n=this._prepareUrl(t);if(null!==n)switch(e.type){case"mousedown":case"touchstart":this._addPrefetchLink(n);break;case"mouseover":this._earlyPrefetch(t,n,"mouseout")}}},{key:"_earlyPrefetch",value:function(t,e,n){var i=this,r=setTimeout(function(){if(r=null,0===i.numOnHover)setTimeout(function(){return i.numOnHover=0},1e3);else if(i.numOnHover>i.config.rateThrottle)return;i.numOnHover++,i._addPrefetchLink(e)},this.config.onHoverDelay);t.addEventListener(n,function e(){t.removeEventListener(n,e,{passive:!0}),null!==r&&(clearTimeout(r),r=null)},{passive:!0})}},{key:"_addPrefetchLink",value:function(i){return this.prefetched.add(i.href),new Promise(function(e,t){var n=document.createElement("link");n.rel="prefetch",n.href=i.href,n.onload=e,n.onerror=t,document.head.appendChild(n)}).catch(function(){})}},{key:"_prepareUrl",value:function(e){if(null===e||"object"!==(void 0===e?"undefined":r(e))||!1 in e||-1===["http:","https:"].indexOf(e.protocol))return null;var t=e.href.substring(0,this.config.siteUrl.length),n=this._getPathname(e.href,t),i={original:e.href,protocol:e.protocol,origin:t,pathname:n,href:t+n};return this._isLinkOk(i)?i:null}},{key:"_getPathname",value:function(e,t){var n=t?e.substring(this.config.siteUrl.length):e;return n.startsWith("/")||(n="/"+n),this._shouldAddTrailingSlash(n)?n+"/":n}},{key:"_shouldAddTrailingSlash",value:function(e){return this.config.usesTrailingSlash&&!e.endsWith("/")&&!this.regex.fileExt.test(e)}},{key:"_isLinkOk",value:function(e){return null!==e&&"object"===(void 0===e?"undefined":r(e))&&(!this.prefetched.has(e.href)&&e.origin===this.config.siteUrl&&-1===e.href.indexOf("?")&&-1===e.href.indexOf("#")&&!this.regex.excludeUris.test(e.href)&&!this.regex.images.test(e.href))}}],[{key:"run",value:function(){"undefined"!=typeof RocketPreloadLinksConfig&&new n(new RocketBrowserCompatibilityChecker({capture:!0,passive:!0}),RocketPreloadLinksConfig).init()}}]),n}();t.run(); }()); </script> <script src="https://www.nervianoms.com/wp-content/themes/hello-elementor/assets/js/hello-frontend.min.js?ver=3.2.1" id="hello-theme-frontend-js"></script> <script src="https://www.nervianoms.com/wp-content/plugins/elementor-pro/assets/lib/smartmenus/jquery.smartmenus.min.js?ver=1.2.1" id="smartmenus-js"></script> <script src="https://www.nervianoms.com/wp-content/uploads/essential-addons-elementor/eael-42.js?ver=1738116821" id="eael-42-js"></script> <script src="https://www.nervianoms.com/wp-includes/js/imagesloaded.min.js?ver=5.0.0" id="imagesloaded-js"></script> <script src="https://www.nervianoms.com/wp-content/uploads/essential-addons-elementor/eael-4855.js?ver=1738292536" id="eael-4855-js"></script> <script src="https://www.nervianoms.com/wp-content/plugins/elementor-pro/assets/js/webpack-pro.runtime.min.js?ver=3.26.3" id="elementor-pro-webpack-runtime-js"></script> <script src="https://www.nervianoms.com/wp-content/plugins/elementor/assets/js/webpack.runtime.min.js?ver=3.26.4" id="elementor-webpack-runtime-js"></script> <script src="https://www.nervianoms.com/wp-content/plugins/elementor/assets/js/frontend-modules.min.js?ver=3.26.4" id="elementor-frontend-modules-js"></script> <script src="https://www.nervianoms.com/wp-includes/js/dist/hooks.min.js?ver=4d63a3d491d11ffd8ac6" id="wp-hooks-js"></script> <script src="https://www.nervianoms.com/wp-includes/js/dist/i18n.min.js?ver=5e580eb46a90c2b997e6" id="wp-i18n-js"></script> <script id="wp-i18n-js-after"> wp.i18n.setLocaleData( { 'text direction\u0004ltr': [ 'ltr' ] } ); </script> <script id="elementor-pro-frontend-js-before"> var ElementorProFrontendConfig = {"ajaxurl":"https:\/\/www.nervianoms.com\/wp-admin\/admin-ajax.php","nonce":"f503f41b41","urls":{"assets":"https:\/\/www.nervianoms.com\/wp-content\/plugins\/elementor-pro\/assets\/","rest":"https:\/\/www.nervianoms.com\/wp-json\/"},"settings":{"lazy_load_background_images":true},"popup":{"hasPopUps":true},"shareButtonsNetworks":{"facebook":{"title":"Facebook","has_counter":true},"twitter":{"title":"Twitter"},"linkedin":{"title":"LinkedIn","has_counter":true},"pinterest":{"title":"Pinterest","has_counter":true},"reddit":{"title":"Reddit","has_counter":true},"vk":{"title":"VK","has_counter":true},"odnoklassniki":{"title":"OK","has_counter":true},"tumblr":{"title":"Tumblr"},"digg":{"title":"Digg"},"skype":{"title":"Skype"},"stumbleupon":{"title":"StumbleUpon","has_counter":true},"mix":{"title":"Mix"},"telegram":{"title":"Telegram"},"pocket":{"title":"Pocket","has_counter":true},"xing":{"title":"XING","has_counter":true},"whatsapp":{"title":"WhatsApp"},"email":{"title":"Email"},"print":{"title":"Print"},"x-twitter":{"title":"X"},"threads":{"title":"Threads"}},"facebook_sdk":{"lang":"en_US","app_id":""},"lottie":{"defaultAnimationUrl":"https:\/\/www.nervianoms.com\/wp-content\/plugins\/elementor-pro\/modules\/lottie\/assets\/animations\/default.json"}}; </script> <script src="https://www.nervianoms.com/wp-content/plugins/elementor-pro/assets/js/frontend.min.js?ver=3.26.3" id="elementor-pro-frontend-js"></script> <script src="https://www.nervianoms.com/wp-includes/js/jquery/ui/core.min.js?ver=1.13.3" id="jquery-ui-core-js"></script> <script id="elementor-frontend-js-before"> var elementorFrontendConfig = {"environmentMode":{"edit":false,"wpPreview":false,"isScriptDebug":false},"i18n":{"shareOnFacebook":"Share on Facebook","shareOnTwitter":"Share on Twitter","pinIt":"Pin it","download":"Download","downloadImage":"Download image","fullscreen":"Fullscreen","zoom":"Zoom","share":"Share","playVideo":"Play Video","previous":"Previous","next":"Next","close":"Close","a11yCarouselPrevSlideMessage":"Previous slide","a11yCarouselNextSlideMessage":"Next slide","a11yCarouselFirstSlideMessage":"This is the first slide","a11yCarouselLastSlideMessage":"This is the last slide","a11yCarouselPaginationBulletMessage":"Go to slide"},"is_rtl":false,"breakpoints":{"xs":0,"sm":480,"md":768,"lg":1025,"xl":1440,"xxl":1600},"responsive":{"breakpoints":{"mobile":{"label":"Mobile Portrait","value":767,"default_value":767,"direction":"max","is_enabled":true},"mobile_extra":{"label":"Mobile Landscape","value":880,"default_value":880,"direction":"max","is_enabled":false},"tablet":{"label":"Tablet Portrait","value":1024,"default_value":1024,"direction":"max","is_enabled":true},"tablet_extra":{"label":"Tablet Landscape","value":1200,"default_value":1200,"direction":"max","is_enabled":false},"laptop":{"label":"Laptop","value":1366,"default_value":1366,"direction":"max","is_enabled":true},"widescreen":{"label":"Widescreen","value":1600,"default_value":2400,"direction":"min","is_enabled":true}},"hasCustomBreakpoints":true},"version":"3.26.4","is_static":false,"experimentalFeatures":{"e_font_icon_svg":true,"additional_custom_breakpoints":true,"container":true,"e_swiper_latest":true,"e_nested_atomic_repeaters":true,"e_onboarding":true,"e_css_smooth_scroll":true,"theme_builder_v2":true,"hello-theme-header-footer":true,"home_screen":true,"nested-elements":true,"editor_v2":true,"e_element_cache":true,"link-in-bio":true,"floating-buttons":true},"urls":{"assets":"https:\/\/www.nervianoms.com\/wp-content\/plugins\/elementor\/assets\/","ajaxurl":"https:\/\/www.nervianoms.com\/wp-admin\/admin-ajax.php","uploadUrl":"https:\/\/www.nervianoms.com\/wp-content\/uploads"},"nonces":{"floatingButtonsClickTracking":"3663c11672"},"swiperClass":"swiper","settings":{"page":[],"editorPreferences":[]},"kit":{"active_breakpoints":["viewport_mobile","viewport_tablet","viewport_laptop","viewport_widescreen"],"viewport_widescreen":1600,"global_image_lightbox":"yes","lightbox_enable_fullscreen":"yes","lightbox_description_src":"description","hello_header_logo_type":"logo","hello_header_menu_layout":"horizontal","hello_footer_logo_type":"logo"},"post":{"id":42,"title":"News%2FEvents%20%26%20Publications%20-%20Nerviano%20Medical%20Sciences","excerpt":"","featuredImage":false}}; </script> <script src="https://www.nervianoms.com/wp-content/plugins/elementor/assets/js/frontend.min.js?ver=3.26.4" id="elementor-frontend-js"></script> <script src="https://www.nervianoms.com/wp-content/plugins/elementor-pro/assets/js/elements-handlers.min.js?ver=3.26.3" id="pro-elements-handlers-js"></script> <style> .unlimited-elements-background-overlay{ position:absolute; top:0px; left:0px; width:100%; height:100%; z-index:0; } .unlimited-elements-background-overlay.uc-bg-front{ z-index:999; } </style> <script type='text/javascript'> jQuery(document).ready(function(){ function ucBackgroundOverlayPutStart(){ var objBG = jQuery(".unlimited-elements-background-overlay").not(".uc-bg-attached"); if(objBG.length == 0) return(false); objBG.each(function(index, bgElement){ var objBgElement = jQuery(bgElement); var targetID = objBgElement.data("forid"); var location = objBgElement.data("location"); switch(location){ case "body": case "body_front": var objTarget = jQuery("body"); break; case "layout": case "layout_front": var objLayout = jQuery("*[data-id=\""+targetID+"\"]"); var objTarget = objLayout.parents(".elementor"); if(objTarget.length > 1) objTarget = jQuery(objTarget[0]); break; default: var objTarget = jQuery("*[data-id=\""+targetID+"\"]"); break; } if(objTarget.length == 0) return(true); var objVideoContainer = objTarget.children(".elementor-background-video-container"); if(objVideoContainer.length == 1) objBgElement.detach().insertAfter(objVideoContainer).show(); else objBgElement.detach().prependTo(objTarget).show(); var objTemplate = objBgElement.children("template"); if(objTemplate.length){ var clonedContent = objTemplate[0].content.cloneNode(true); var objScripts = jQuery(clonedContent).find("script"); if(objScripts.length) objScripts.attr("type","text/javascript"); objBgElement.append(clonedContent); objTemplate.remove(); } objBgElement.trigger("bg_attached"); objBgElement.addClass("uc-bg-attached"); }); } ucBackgroundOverlayPutStart(); jQuery( document ).on( 'elementor/popup/show', ucBackgroundOverlayPutStart); jQuery( "body" ).on( 'uc_dom_updated', ucBackgroundOverlayPutStart); }); </script>  <script async src="https://www.googletagmanager.com/gtag/js?id=G-J2R3TN1138"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-J2R3TN1138'); </script> <script> jQuery(document).ready(function($) { // Find the previous and next post navigation elements var $prevNav = $('.elementor-post-navigation__prev'); var $nextNav = $('.elementor-post-navigation__next'); // Get the HTML content of previous and next navigation elements var prevHtml = $prevNav.html(); var nextHtml = $nextNav.html(); // Update the HTML content of previous and next navigation elements $prevNav.html(nextHtml); $nextNav.html(prevHtml); }); </script> <script> jQuery(document).ready(function ($) { const publications = $(".publications"); const accordionItems = publications.find("details"); const expandButton = publications.find(".elementor-button-text"); // Open first accordion on page load accordionItems.first().attr("open", true); // Expand All / Collapse All publications.find(".elementor-button").on("click", function (e) { e.preventDefault(); const allOpen = accordionItems.filter("[open]").length === accordionItems.length; if (allOpen) { accordionItems.removeAttr("open"); expandButton.text("Expand All"); } else { accordionItems.attr("open", true); expandButton.text("Collapse All"); } }); // Individual accordion click accordionItems.on("click", function () { // Prevent auto-collapse by not changing the state unless clicked const isOpen = $(this).attr("open"); if (isOpen) { $(this).removeAttr("open"); } else { accordionItems.removeAttr("open"); // Close all $(this).attr("open", true); // Open the clicked one } // Scroll to the clicked accordion item const offsetTop = $(this).offset().top; $("html, body").animate({ scrollTop: offsetTop - 20 }, 300); }); }); </script> <script> jQuery(document).ready(function($) { const url = window.location.href; // Check if the URL contains # with extra value if (url.indexOf('#') !== -1 && url.indexOf('#') < url.length - 1) { const extraValue = url.substring(url.indexOf('#') + 1); jQuery('#' + extraValue).closest('.target-info').find('td').toggle(); jQuery('#' + extraValue).closest('.target-info').toggleClass('active'); } //jQuery('#expandAll').on('click',function(event){event.preventDefault();jQuery('.target-info').find('td').toggle();jQuery('.target-info').addClass('active');}); //jQuery('#collapseAll').on('click',function(event){event.preventDefault();jQuery('.target-info').find('td').toggle();jQuery('.target-info').removeClass('active');}); }); jQuery(document).ready(function() { jQuery('.target-info-toggle').on('click', function(event) { event.preventDefault(); const targetInfo = jQuery(this).closest('.data').nextAll('.target-info').first(); const img = jQuery(this).find('img'); // Toggle display and active class on target-info if (targetInfo.hasClass('active')) { targetInfo.removeClass('active').find('td').hide(); img.attr('src', '/wp-content/uploads/2024/10/plus.svg'); // Change to plus on hide } else { targetInfo.addClass('active').find('td').show(); img.attr('src', '/wp-content/uploads/2024/11/minus.svg'); // Change to minus on show } }); }); jQuery(document).ready(function() { // Show the first .target-info div and set icon to minus.svg on page load const firstActive = jQuery('#first-active'); firstActive.find('td').show(); firstActive.addClass('active'); // Set the image source to minus.svg for the first active row firstActive.prev('.data').find('.target-info-toggle img').attr('src', '/wp-content/uploads/2024/11/minus.svg'); jQuery('#expandAll').on('click', function(event) { event.preventDefault(); // Check if all rows are currently hidden const allHidden = jQuery('.target-info').find('td:hidden').length === jQuery('.target-info').length; if (allHidden) { // Show all rows and set button text to 'Collapse All' jQuery('.target-info').find('td').show(); jQuery('.target-info').addClass('active'); jQuery('.target-info-toggle img').attr('src', '/wp-content/uploads/2024/11/minus.svg'); jQuery('#expandAll').text('- Collapse All'); } else { // Hide all rows and set button text to 'Expand All' jQuery('.target-info').find('td').hide(); jQuery('.target-info').removeClass('active'); jQuery('.target-info-toggle img').attr('src', '/wp-content/uploads/2024/10/plus.svg'); jQuery('#expandAll').text('+ Expand All'); } }); }); window.addEventListener('hashchange', () => { const newHash = window.location.hash.slice(1); // Get the new hash value without # console.log("Hash changed to:", newHash); jQuery('#' + newHash).closest('.target-info').find('td').toggle(); jQuery('#' + newHash).closest('.target-info').toggleClass('active'); }); </script> </body> </html>