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href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%A2%D0%B0%D0%BA%D0%BC%D0%B8%D1%87%D0%B5%D1%9A%D0%B5_%D1%83_%D0%BF%D0%B8%D1%81%D0%B0%D1%9A%D1%83_%D1%87%D0%BB%D0%B0%D0%BD%D0%B0%D0%BA%D0%B0/%D0%A3_%D1%81%D0%B2%D0%B5%D1%82%D1%83_%D0%A4%D0%BB%D0%BE%D1%80%D0%B5_%D0%B8_%D0%A4%D0%B0%D1%83%D0%BD%D0%B5\" title=\"Википедија:Такмичење у писању чланака/У свету Флоре и Фауне\"\u003EФлоре и фауне\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EПридружите се \u003Cb\u003E\u003Ca href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%A3%D1%80%D0%B5%D1%92%D0%B8%D0%B2%D0%B0%D1%87%D0%BA%D0%B8_%D0%BC%D0%B0%D1%80%D0%B0%D1%82%D0%BE%D0%BD_%D0%92%D0%B8%D0%BA%D0%B8_%D0%B2%D0%BE%D0%BB%D0%B8_%D1%98%D0%B0%D0%B2%D0%BD%D1%83_%D1%83%D0%BC%D0%B5%D1%82%D0%BD%D0%BE%D1%81%D1%82_%D0%B8_%D0%B3%D1%80%D0%BE%D0%B1%D0%BD%D0%B0_%D0%BE%D0%B1%D0%B5%D0%BB%D0%B5%D0%B6%D1%98%D0%B0_2024.\" title=\"Википедија:Уређивачки маратон Вики воли јавну уметност и гробна обележја 2024.\"\u003EУређивачком маратону Вики воли јавну уметност и гробна обележја 2024\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv 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значајних жена\u003C/a\u003E\u003C/b\u003E на Викицитату.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EПридружите се \u003Cb\u003E\u003Ca href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%90%D0%BA%D1%86%D0%B8%D1%98%D0%B0_%D0%BF%D1%80%D0%BE%D1%88%D0%B8%D1%80%D0%B8%D0%B2%D0%B0%D1%9A%D0%B0_%D0%BA%D0%BB%D0%B8%D1%86%D0%B0\" title=\"Википедија:Акција проширивања клица\"\u003Eакцији проширивања клица\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E";}}());</script></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Сајт"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Садржај" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Садржај</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">помери на страну</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">сакриј</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Почетак</div> </a> </li> <li id="toc-Struktura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Struktura"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Struktura</span> </div> </a> <ul id="toc-Struktura-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Funkcija" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Funkcija"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Funkcija</span> </div> </a> <button aria-controls="toc-Funkcija-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Садржај одељка Funkcija</span> </button> <ul id="toc-Funkcija-sublist" class="vector-toc-list"> <li id="toc-Hemotaksa" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Hemotaksa"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.1</span> <span>Hemotaksa</span> </div> </a> <ul id="toc-Hemotaksa-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Drugo" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Drugo"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2</span> <span>Drugo</span> </div> </a> <ul id="toc-Drugo-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Receptor" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Receptor"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Receptor</span> </div> </a> <ul id="toc-Receptor-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Gen" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Gen"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Gen</span> </div> </a> <ul id="toc-Gen-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reference" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Reference"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Reference</span> </div> </a> <ul id="toc-Reference-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Literatura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Literatura"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Literatura</span> </div> </a> <ul id="toc-Literatura-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Садржај" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Прикажи/сакриј садржај" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Прикажи/сакриј садржај</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">CXCL12</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Чланак на другим језицима. Доступан на: 12" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-12" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">12 језика</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/CXCL12" title="CXCL12 — босански" lang="bs" hreflang="bs" data-title="CXCL12" data-language-autonym="Bosanski" data-language-local-name="босански" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/CXCL12" title="CXCL12 — велшки" lang="cy" hreflang="cy" data-title="CXCL12" data-language-autonym="Cymraeg" data-language-local-name="велшки" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/CXCL12" title="CXCL12 — немачки" lang="de" hreflang="de" data-title="CXCL12" data-language-autonym="Deutsch" data-language-local-name="немачки" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Stromal_cell-derived_factor_1" title="Stromal cell-derived factor 1 — енглески" lang="en" hreflang="en" data-title="Stromal cell-derived factor 1" data-language-autonym="English" data-language-local-name="енглески" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/SDF1" title="SDF1 — персијски" lang="fa" hreflang="fa" data-title="SDF1" data-language-autonym="فارسی" data-language-local-name="персијски" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/CXCL12" title="CXCL12 — француски" lang="fr" hreflang="fr" data-title="CXCL12" data-language-autonym="Français" data-language-local-name="француски" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/CXCL12" title="CXCL12 — јапански" lang="ja" hreflang="ja" data-title="CXCL12" data-language-autonym="日本語" data-language-local-name="јапански" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/SDF-1" title="SDF-1 — холандски" lang="nl" hreflang="nl" data-title="SDF-1" data-language-autonym="Nederlands" data-language-local-name="холандски" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/SDF-1_(%D0%B1%D0%B5%D0%BB%D0%BE%D0%BA)" title="SDF-1 (белок) — руски" lang="ru" hreflang="ru" data-title="SDF-1 (белок)" data-language-autonym="Русский" data-language-local-name="руски" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/CXCL12" title="CXCL12 — српскохрватски" lang="sh" hreflang="sh" data-title="CXCL12" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="српскохрватски" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/CXCL12" title="CXCL12 — украјински" lang="uk" hreflang="uk" data-title="CXCL12" data-language-autonym="Українська" data-language-local-name="украјински" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/CXCL12" title="CXCL12 — кинески" lang="zh" hreflang="zh" data-title="CXCL12" data-language-autonym="中文" data-language-local-name="кинески" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q408598#sitelinks-wikipedia" title="Уреди међујезичке везе" class="wbc-editpage">Уреди везе</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Именски простори"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/CXCL12" title="Прочитајте овај чланак [c]" accesskey="c"><span>Чланак</span></a></li><li id="ca-talk" class="new vector-tab-noicon mw-list-item"><a href="/w/index.php?title=%D0%A0%D0%B0%D0%B7%D0%B3%D0%BE%D0%B2%D0%BE%D1%80:CXCL12&action=edit&redlink=1" rel="discussion" class="new" title="Разговарајте о страници (страница не постоји) [t]" accesskey="t"><span>Разговор</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown " > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Промени варијанту језика" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Ћир./lat.</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-varlang-0" class="selected ca-variants-sr mw-list-item"><a href="/sr/CXCL12" lang="sr" hreflang="sr"><span>Ћир./lat.</span></a></li><li id="ca-varlang-1" class="ca-variants-sr-Cyrl mw-list-item"><a href="/sr-ec/CXCL12" lang="sr-Cyrl" hreflang="sr-Cyrl"><span>Ћирилица</span></a></li><li id="ca-varlang-2" class="ca-variants-sr-Latn mw-list-item"><a href="/sr-el/CXCL12" lang="sr-Latn" hreflang="sr-Latn"><span>Latinica</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Погледи"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/CXCL12"><span>Читај</span></a></li><li id="ca-ve-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=CXCL12&veaction=edit" title="Уредите ову страницу [v]" accesskey="v"><span>Уреди</span></a></li><li id="ca-edit" class="collapsible vector-tab-noicon mw-list-item"><a href="/w/index.php?title=CXCL12&action=edit" title="Уредите изворни код ове странице [e]" accesskey="e"><span>Уреди извор</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=CXCL12&action=history" title="Историја [h]" accesskey="h"><span>Историја</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Алатке странице"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Алатке" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Алатке</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Алатке</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">помери на страну</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">сакриј</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="Више опција" > <div class="vector-menu-heading"> Радње </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/CXCL12"><span>Читај</span></a></li><li id="ca-more-ve-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=CXCL12&veaction=edit" title="Уредите ову страницу [v]" accesskey="v"><span>Уреди</span></a></li><li id="ca-more-edit" class="collapsible vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=CXCL12&action=edit" title="Уредите изворни код ове странице [e]" accesskey="e"><span>Уреди извор</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=CXCL12&action=history"><span>Историја</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> Опште </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A8%D1%82%D0%B0_%D0%B2%D0%BE%D0%B4%D0%B8_%D0%BE%D0%B2%D0%B0%D0%BC%D0%BE/CXCL12" title="Списак свих вики страница које воде овамо [j]" accesskey="j"><span>Шта води овамо</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%9F%D0%BE%D0%B2%D0%B5%D0%B7%D0%B0%D0%BD%D0%B5_%D0%B8%D0%B7%D0%BC%D0%B5%D0%BD%D0%B5/CXCL12" rel="nofollow" title="Скорашње измене страница које су повезане с овом [k]" accesskey="k"><span>Повезане измене</span></a></li><li id="t-upload" class="mw-list-item"><a href="/wiki/Википедија:Водич_за_отпремање" title="Поставите слике и снимке [u]" accesskey="u"><span>Отпреми датотеку</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%B5_%D1%81%D1%82%D1%80%D0%B0%D0%BD%D0%B8%D1%86%D0%B5" title="Списак свих посебних страница [q]" accesskey="q"><span>Посебне странице</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=CXCL12&oldid=27556816" title="Трајна веза до ове измене на овој страници"><span>Трајна веза</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=CXCL12&action=info" title="Више информација о овој страници"><span>Подаци о страници</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A6%D0%B8%D1%82%D0%B8%D1%80%D0%B0%D1%98&page=CXCL12&id=27556816&wpFormIdentifier=titleform" title="Информације о томе како цитирати ову страницу"><span>Цитирај страницу</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A1%D0%BA%D1%80%D0%B0%D1%9B%D0%B8%D0%B2%D0%B0%D1%87_%D0%B0%D0%B4%D1%80%D0%B5%D1%81%D0%B0&url=https%3A%2F%2Fsr.wikipedia.org%2Fwiki%2FCXCL12"><span>Кратки URL</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:QrCode&url=https%3A%2F%2Fsr.wikipedia.org%2Fwiki%2FCXCL12"><span>Преузми QR код</span></a></li> </ul> </div> </div> <div id="p-electronpdfservice-sidebar-portlet-heading" class="vector-menu mw-portlet mw-portlet-electronpdfservice-sidebar-portlet-heading" > <div class="vector-menu-heading"> Штампање/извоз </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="electron-print_pdf" class="mw-list-item"><a href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:DownloadAsPdf&page=CXCL12&action=show-download-screen"><span>Преузми у PDF-у</span></a></li><li id="t-print" class="mw-list-item"><a href="javascript:print();" rel="alternate" title="Одштампајте ову страницу [p]" accesskey="p"><span>Одштампај</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> На другим пројектима </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q408598" title="Веза ка ставци на спремишту података [g]" accesskey="g"><span>Ставка на Википодацима</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Алатке странице"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Изглед"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Изглед</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">помери на страну</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">сакриј</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">С Википедије, слободне енциклопедије</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="sr" dir="ltr"><table align="right" border="0" style="background:#fff; width:280px;" class="plainlinks"> <tbody><tr><td></td></tr></tbody></table><style data-mw-deduplicate="TemplateStyles:r28440203">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}body.skin-minerva .mw-parser-output .infobox-header,body.skin-minerva .mw-parser-output .infobox-subheader,body.skin-minerva .mw-parser-output .infobox-above,body.skin-minerva .mw-parser-output .infobox-title,body.skin-minerva .mw-parser-output .infobox-image,body.skin-minerva .mw-parser-output .infobox-full-data,body.skin-minerva .mw-parser-output .infobox-below{text-align:center}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox"><tbody><tr><th colspan="4" class="infobox-above">Hemokin (C-X-C motif) ligand 12<br />(stromalne ćelije - izvedeni faktor 1)</th></tr><tr><td colspan="4" class="infobox-image"> <span class="mw-image-border" typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:Protein_CXCL12_PDB_1a15.png" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/86/Protein_CXCL12_PDB_1a15.png/250px-Protein_CXCL12_PDB_1a15.png" decoding="async" width="250" height="237" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/86/Protein_CXCL12_PDB_1a15.png/375px-Protein_CXCL12_PDB_1a15.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/86/Protein_CXCL12_PDB_1a15.png/500px-Protein_CXCL12_PDB_1a15.png 2x" data-file-width="731" data-file-height="694" /></a></span><div class="infobox-caption"><a href="/wiki/Protein_Data_Bank" class="mw-redirect" title="Protein Data Bank">PDB</a> prikaz baziran na <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1a15">1a15</a></span>.</div></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Dostupne strukture</th></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1a15">1a15</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1qg7">1qg7</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1sdf">1sdf</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1vmc">1vmc</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2j7z">2j7z</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2nwg">2nwg</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2sdf">2sdf</a></span></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Identifikatori</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Organizacija_za_ljudski_genom" title="Organizacija za ljudski genom">Simboli</a></th><td colspan="3" class="infobox-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=10672">CXCL12</a>; PBSF; SCYB12; SDF-1a; SDF-1b; SDF1; SDF1A; SDF1B; TLSF-a; TLSF-b; TPAR1</span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Vanjski ID</th><td colspan="3" class="infobox-data" style="background-color: #eee"> <span class="plainlinks"><a href="/wiki/%D0%9C%D0%B5%D0%BD%D0%B4%D0%B5%D0%BB%D0%BE%D0%B2%D1%81%D0%BA%D0%BE_%D0%BD%D0%B0%D1%81%D0%BB%D0%B5%D1%92%D0%B8%D0%B2%D0%B0%D1%9A%D0%B5_%D0%BA%D0%BE%D0%B4_%D1%87%D0%BE%D0%B2%D0%B5%D0%BA%D0%B0" title="Менделовско наслеђивање код човека">OMIM</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600835">600835 </a></span> <span class="plainlinks"><a href="/wiki/%D0%98%D0%BD%D1%84%D0%BE%D1%80%D0%BC%D0%B0%D1%82%D0%B8%D0%BA%D0%B0_%D0%BC%D0%B8%D1%88%D1%98%D0%B5%D0%B3_%D0%B3%D0%B5%D0%BD%D0%BE%D0%BC%D0%B0" title="Информатика мишјег генома">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:103556">103556 </a></span> <span class="plainlinks"><a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=507">507 </a></span> <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=6387">CXCL12 Gene</a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <table class="collapsible collapsed" style="border: none; padding: 0; margin: 0; width: 100%; text-align: left"> <tbody><tr style="background-color: #ddd; text-align: center"> <th colspan="2"><a href="/wiki/Ontologija_gena" title="Ontologija gena">Ontologija gena</a></th> </tr> <tr> <th style="background-color: #c3fdb8">Molekularna funkcija</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0004871">transdukcija signala</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0008009">hemokinska aktivnost</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0008083">aktivnost faktora rasta</a></span><br /></td> </tr> <tr> <th style="background-color: #c3fdb8">Celularna komponenta</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005576">ekstracelularni region</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005615">ekstracelularni prostor</a></span><br /></td> </tr> <tr> <th style="background-color: #c3fdb8">Biološki proces</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0006874">ćelijska homeostaza kalcijum jona</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0006935">hemotaksa</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0006954">inflamatorni odgovor</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0006955">imunski odgovor</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007155">ćelijska adhezija</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007165">transdukcija signala</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007186">G-protein spregnuti receptor proteinski signalni put</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007267">interćelijska signalizacija</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0008015">cirkulacija</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0008064">regulacija aktin polimerizacije i/ili depolimerizacije</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0009615">respons na viruse</a></span><br /></td> </tr> </tbody></table></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Pregled RNK izražavanja</th></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PBB_GE_CXCL12_209687_at_tn.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2c/PBB_GE_CXCL12_209687_at_tn.png/250px-PBB_GE_CXCL12_209687_at_tn.png" decoding="async" width="250" height="132" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/2/2c/PBB_GE_CXCL12_209687_at_tn.png 1.5x" data-file-width="255" data-file-height="135" /></a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PBB_GE_CXCL12_203666_at_tn.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/ba/PBB_GE_CXCL12_203666_at_tn.png/250px-PBB_GE_CXCL12_203666_at_tn.png" decoding="async" width="250" height="132" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/b/ba/PBB_GE_CXCL12_203666_at_tn.png 1.5x" data-file-width="255" data-file-height="135" /></a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.gnf.org/gene/6387/Dodatni">podaci</a></span></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Ortolozi</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Vrsta</th><td class="infobox-data infobox-data-a"> <b>Čovek</b></td><td class="infobox-data infobox-data-b"> <b>Miš</b></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=6387&rn=1">6387</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=20315&rn=1">20315</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Ensembl" title="Ensembl">Ensembl</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000107562;db=core">ENSG00000107562</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000061353;db=core">ENSMUSG00000061353</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/P48061">P48061</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/Q4FJL5">Q4FJL5</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">RefSeq (mRNA)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_000609">NM_000609</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001012477">NM_001012477</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">RefSeq (protein)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_000600">NP_000600</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001012495">NP_001012495</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Lokacija (UCSC)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg18&position=chr10:44185619-44200548">Chr 10:<br />44.19 - 44.2 Mb</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm8&position=chr6:117134182-117146986">Chr 6:<br />117.13 - 117.15 Mb</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/PubMed" title="PubMed">PubMed</a> pretraga</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=6387">[1]</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=20315">[2]</a></span></td></tr></tbody></table> <p><b>CXCL12</b>, ili <b>SDF-1</b> (<a href="/w/index.php?title=Stromalne_%C4%87elije&action=edit&redlink=1" class="new" title="Stromalne ćelije (страница не постоји)">stromalne ćelije</a>-izvedeni faktor-1), je mali <a href="/wiki/%D0%A6%D0%B8%D1%82%D0%BE%D0%BA%D0%B8%D0%BD" title="Цитокин">citokin</a> iz <a href="/wiki/Hemokin" class="mw-redirect" title="Hemokin">hemokin</a> familije. Ovaj molekul je zvanično zove <b>hemokin (C-X-C motiv) ligand 12</b>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p><p>SDF-1 alfa i beta su mali citokini iz <a href="/w/index.php?title=Interkrin&action=edit&redlink=1" class="new" title="Interkrin (страница не постоји)">interkrin</a> familije čiji članovi aktiviraju <a href="/wiki/%D0%9B%D0%B5%D1%83%D0%BA%D0%BE%D1%86%D0%B8%D1%82" class="mw-redirect" title="Леукоцит">leukocite</a> i često indukuju proinflamatorne stimuluse kao što su <a href="/wiki/%D0%9B%D0%B8%D0%BF%D0%BE%D0%BF%D0%BE%D0%BB%D0%B8%D1%81%D0%B0%D1%85%D0%B0%D1%80%D0%B8%D0%B4" class="mw-redirect" title="Липополисахарид">lipopolisaharid</a>, <a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">TNF</a>, ili <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_1" title="Интерлеукин 1">IL1</a>. Interkrini su karakterizovani prisustvom 4 konzervirana <a href="/wiki/Cistein" title="Cistein">cisteina</a> koji formiraju dva <a href="/wiki/Disulfidni_most" class="mw-redirect" title="Disulfidni most">disulfidna mosta</a>. The SDF1 proteini pripadaju CXC grupi citokina.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Struktura">Struktura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CXCL12&veaction=edit&section=1" title="Уредите одељак „Struktura”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=CXCL12&action=edit&section=1" title="Уреди извор одељка: Struktura"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>SDF-1 proizvodi u dve forme, SDF-1α/CXCL12a i SDF-1β/CXCL12b, putem alternativnog splajsovanja gena.<sup id="cite_ref-pmid14525775_3-0" class="reference"><a href="#cite_note-pmid14525775-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Funkcija">Funkcija</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CXCL12&veaction=edit&section=2" title="Уредите одељак „Funkcija”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=CXCL12&action=edit&section=2" title="Уреди извор одељка: Funkcija"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Hemotaksa">Hemotaksa</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CXCL12&veaction=edit&section=3" title="Уредите одељак „Hemotaksa”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=CXCL12&action=edit&section=3" title="Уреди извор одељка: Hemotaksa"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>CXCL12 izaziva potentnu <a href="/wiki/Hemotaksa" title="Hemotaksa">hemotaksu</a> <a href="/wiki/%D0%9B%D0%B8%D0%BC%D1%84%D0%BE%D1%86%D0%B8%D1%82" title="Лимфоцит">limfocita</a>.<sup id="cite_ref-pmid9064327_4-0" class="reference"><a href="#cite_note-pmid9064327-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid12684531_5-0" class="reference"><a href="#cite_note-pmid12684531-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid12957092_6-0" class="reference"><a href="#cite_note-pmid12957092-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid9689100_7-0" class="reference"><a href="#cite_note-pmid9689100-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Tokom <a href="/w/index.php?title=Embriogeneza&action=edit&redlink=1" class="new" title="Embriogeneza (страница не постоји)">embriogeneze</a> on usmerava migraciju hematopoetskih ćelija i formiranje velikih krvnih sudova. Miševi bez CXCL12 gena su letalni pre rođenja, ili u toku prvog sata života. </p><p>Kod odraslih CXCL12 igra važnu ulogu u angiogenezi putem regrutovanja endotelnih progenitorskih ćelija (EPC) iz koštane srži kroz CXCR4 zavistan mehanizam.<sup id="cite_ref-pmid17878755_8-0" class="reference"><a href="#cite_note-pmid17878755-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> Ova funkcija čini CXCL12 veoma važnim faktorom u karcinogenezi i neovaskularizaciji vezanoj za progresiju tumora.<sup id="cite_ref-pmid16943240_9-0" class="reference"><a href="#cite_note-pmid16943240-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> CXCL12 takođe ima ulogu u metastazi tumora gde su ćelije raka koje izražavaju CXCR4 receptor privučene ka metastaznim ciljnim tkivima koja oslobađaju ligand, CXCL12.<sup id="cite_ref-pmid11242036_10-0" class="reference"><a href="#cite_note-pmid11242036-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> Kod raka dojke, međutim, povećano CXCL12 izražavanje određuje umanjeni rizik od metastaze.<sup id="cite_ref-pmid19646861_11-0" class="reference"><a href="#cite_note-pmid19646861-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid17724466_12-0" class="reference"><a href="#cite_note-pmid17724466-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Drugo">Drugo</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CXCL12&veaction=edit&section=4" title="Уредите одељак „Drugo”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=CXCL12&action=edit&section=4" title="Уреди извор одељка: Drugo"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Za CXCL12 je bilo pokazano da je izražen u mnogim tkivima kod miševa (uključujući <a href="/wiki/%D0%9C%D0%BE%D0%B7%D0%B0%D0%BA" title="Мозак">mozak</a>, <a href="/wiki/%D0%A2%D0%B8%D0%BC%D1%83%D1%81" class="mw-redirect" title="Тимус">timus</a>, <a href="/wiki/%D0%A1%D1%80%D1%86%D0%B5" title="Срце">srce</a>, <a href="/wiki/%D0%9F%D0%BB%D1%83%D1%9B%D0%B0" title="Плућа">pluća</a>, <a href="/wiki/%D0%88%D0%B5%D1%82%D1%80%D0%B0" title="Јетра">jetru</a>, <a href="/wiki/%D0%91%D1%83%D0%B1%D1%80%D0%B5%D0%B3" title="Бубрег">bubrege</a>, <a href="/wiki/%D0%A1%D0%BB%D0%B5%D0%B7%D0%B8%D0%BD%D0%B0" title="Слезина">slezinu</a> i <a href="/wiki/%D0%9A%D0%B8%D1%87%D0%BC%D0%B5%D0%BD%D0%B0_%D0%BC%D0%BE%D0%B6%D0%B4%D0%B8%D0%BD%D0%B0" title="Кичмена мождина">kičmenu moždinu</a>). </p> <div class="mw-heading mw-heading2"><h2 id="Receptor">Receptor</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CXCL12&veaction=edit&section=5" title="Уредите одељак „Receptor”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=CXCL12&action=edit&section=5" title="Уреди извор одељка: Receptor"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/w/index.php?title=Hemokin_receptor&action=edit&redlink=1" class="new" title="Hemokin receptor (страница не постоји)">Receptor</a> za ovaj hemokin je <a href="/w/index.php?title=CXC_hemokin_receptori&action=edit&redlink=1" class="new" title="CXC hemokin receptori (страница не постоји)">CXCR4</a>, koji je ranije bio nazivan fuzin.<sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> CXCL12-CXCR4 interakcija je nekad bila smatrana eksluzivnom (za razliku od drugih hemokina i njihovih receptora), ali je nedavno bilo predloženo da se CXCL12 možda takođe vezuje za CXCR7 receptor.<sup id="cite_ref-pmid16107333_14-0" class="reference"><a href="#cite_note-pmid16107333-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid16940167_15-0" class="reference"><a href="#cite_note-pmid16940167-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Gen">Gen</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CXCL12&veaction=edit&section=6" title="Уредите одељак „Gen”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=CXCL12&action=edit&section=6" title="Уреди извор одељка: Gen"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Gene za CXCL12 je lociran na ljudskom <a href="/wiki/%D0%A5%D1%80%D0%BE%D0%BC%D0%BE%D0%B7%D0%BE%D0%BC_10_(%D1%87%D0%BE%D0%B2%D0%B5%D0%BA)" title="Хромозом 10 (човек)">hromozomu 10</a>.<sup id="cite_ref-pmid7490086_16-0" class="reference"><a href="#cite_note-pmid7490086-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid15164054_17-0" class="reference"><a href="#cite_note-pmid15164054-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> Kod ljudi i miševa CXCL12 i CXCR4 imaju visok identitet sekvence: 99% i 90%, respektivno. </p> <div class="mw-heading mw-heading2"><h2 id="Reference">Reference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CXCL12&veaction=edit&section=7" title="Уредите одељак „Reference”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=CXCL12&action=edit&section=7" title="Уреди извор одељка: Reference"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r28440201">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist 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(<a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%98%D0%B0:CS1_%D0%BE%D0%B4%D1%80%D0%B6%D0%B0%D0%B2%D0%B0%D1%9A%D0%B5:_%D0%95%D0%BA%D1%81%D0%BF%D0%BB%D0%B8%D1%86%D0%B8%D1%82%D0%BD%D0%B0_%D1%83%D0%BF%D0%BE%D1%82%D1%80%D0%B5%D0%B1%D0%B0_et_al." title="Категорија:CS1 одржавање: Експлицитна употреба et al.">веза</a>)</span></span> </li> <li id="cite_note-pmid15164054-17"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid15164054_17-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Deloukas P; Earthrowl ME; Grafham DV; et al. 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(<a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%98%D0%B0:CS1_%D0%BE%D0%B4%D1%80%D0%B6%D0%B0%D0%B2%D0%B0%D1%9A%D0%B5:_%D0%95%D0%BA%D1%81%D0%BF%D0%BB%D0%B8%D1%86%D0%B8%D1%82%D0%BD%D0%B0_%D1%83%D0%BF%D0%BE%D1%82%D1%80%D0%B5%D0%B1%D0%B0_et_al." title="Категорија:CS1 одржавање: Експлицитна употреба et al.">веза</a>)</span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Literatura">Literatura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=CXCL12&veaction=edit&section=8" title="Уредите одељак „Literatura”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=CXCL12&action=edit&section=8" title="Уреди извор одељка: Literatura"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r28440192">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-count references-column-count-2" style="column-count: 2;"> <ul><li><cite class="citation journal">Kucia M; Reca R; Miekus K; et al. (2005). „Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis”. <i>Stem Cells</i>. <b>23</b> (7): 879—94. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15888687">15888687</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1634%2Fstemcells.2004-0342">10.1634/stemcells.2004-0342</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3ACXCL12&rft.atitle=Trafficking+of+normal+stem+cells+and+metastasis+of+cancer+stem+cells+involve+similar+mechanisms%3A+pivotal+role+of+the+SDF-1-CXCR4+axis&rft.au=Kucia+M&rft.au=Miekus+K&rft.au=Reca+R&rft.date=2005&rft.genre=article&rft.issue=7&rft.jtitle=Stem+Cells&rft.pages=879-94&rft.volume=23&rft_id=info%3Adoi%2F10.1634%2Fstemcells.2004-0342&rft_id=info%3Apmid%2F15888687&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33; margin-left:0.3em">CS1 одржавање: Експлицитна употреба et al. (<a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%98%D0%B0:CS1_%D0%BE%D0%B4%D1%80%D0%B6%D0%B0%D0%B2%D0%B0%D1%9A%D0%B5:_%D0%95%D0%BA%D1%81%D0%BF%D0%BB%D0%B8%D1%86%D0%B8%D1%82%D0%BD%D0%B0_%D1%83%D0%BF%D0%BE%D1%82%D1%80%D0%B5%D0%B1%D0%B0_et_al." title="Категорија:CS1 одржавање: Експлицитна употреба et al.">веза</a>)</span></li> <li><cite class="citation journal">Kryczek I; Wei S; Keller E; et al. (2007). „Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis”. <i>Am. J. Physiol., Cell Physiol</i>. <b>292</b> (3): C987—95. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16943240">16943240</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fajpcell.00406.2006">10.1152/ajpcell.00406.2006</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3ACXCL12&rft.atitle=Stroma-derived+factor+%28SDF-1%2FCXCL12%29+and+human+tumor+pathogenesis&rft.au=Keller+E&rft.au=Kryczek+I&rft.au=Wei+S&rft.date=2007&rft.genre=article&rft.issue=3&rft.jtitle=Am.+J.+Physiol.%2C+Cell+Physiol.&rft.pages=C987-95&rft.volume=292&rft_id=info%3Adoi%2F10.1152%2Fajpcell.00406.2006&rft_id=info%3Apmid%2F16943240&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33; margin-left:0.3em">CS1 одржавање: Експлицитна употреба et al. (<a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%98%D0%B0:CS1_%D0%BE%D0%B4%D1%80%D0%B6%D0%B0%D0%B2%D0%B0%D1%9A%D0%B5:_%D0%95%D0%BA%D1%81%D0%BF%D0%BB%D0%B8%D1%86%D0%B8%D1%82%D0%BD%D0%B0_%D1%83%D0%BF%D0%BE%D1%82%D1%80%D0%B5%D0%B1%D0%B0_et_al." title="Категорија:CS1 одржавање: Експлицитна употреба et al.">веза</a>)</span></li> <li><cite class="citation journal">Stellos K, Gawaz M (2007). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_seminars-in-thrombosis-and-hemostasis_2007-03_33_2/page/159">„Platelets and stromal cell-derived factor-1 in progenitor cell recruitment”</a>. <i>Semin. Thromb. 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(2007). „Clinical importance and therapeutic implications of the pivotal CXCL12-CXCR4 (chemokine ligand-receptor) interaction in cancer cell migration”. <i>Tumour Biol</i>. <b>28</b> (3): 123—31. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17510563">17510563</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1159%2F000102979">10.1159/000102979</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3ACXCL12&rft.atitle=Clinical+importance+and+therapeutic+implications+of+the+pivotal+CXCL12-CXCR4+%28chemokine+ligand-receptor%29+interaction+in+cancer+cell+migration&rft.au=Ahmed+H&rft.au=Arya+M&rft.au=Silhi+N&rft.date=2007&rft.genre=article&rft.issue=3&rft.jtitle=Tumour+Biol.&rft.pages=123-31&rft.volume=28&rft_id=info%3Adoi%2F10.1159%2F000102979&rft_id=info%3Apmid%2F17510563&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33; margin-left:0.3em">CS1 одржавање: Експлицитна употреба et al. (<a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%98%D0%B0:CS1_%D0%BE%D0%B4%D1%80%D0%B6%D0%B0%D0%B2%D0%B0%D1%9A%D0%B5:_%D0%95%D0%BA%D1%81%D0%BF%D0%BB%D0%B8%D1%86%D0%B8%D1%82%D0%BD%D0%B0_%D1%83%D0%BF%D0%BE%D1%82%D1%80%D0%B5%D0%B1%D0%B0_et_al." title="Категорија:CS1 одржавање: Експлицитна употреба et al.">веза</a>)</span></li></ul> </div> <div style="clear:both;"></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r25469611">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol 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src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d0/PDB_2sdf_EBI.jpg/180px-PDB_2sdf_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d0/PDB_2sdf_EBI.jpg/270px-PDB_2sdf_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d0/PDB_2sdf_EBI.jpg/360px-PDB_2sdf_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2sdf">2sdf</a></span></b>: Rešenje SDF-1 strukture, <a href="/wiki/%D0%9D%D0%9C%D0%A0" class="mw-redirect" title="НМР">NMR</a>, 30 struktura</div> </li> </ul></div></div></div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r25469611"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r24365370"></div><div role="navigation" 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title="Разговарајте о шаблону" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">р</abbr></a></li><li class="nv-уреди"><a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A3%D1%80%D0%B5%D0%B4%D0%B8_%D1%81%D1%82%D1%80%D0%B0%D0%BD%D0%B8%D1%86%D1%83/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Citokini-lat" title="Посебно:Уреди страницу/Шаблон:Citokini-lat"><abbr title="Уредите шаблон" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">у</abbr></a></li></ul></div><div id="Ćelijska_komunikacija:_Citokini" style="font-size:114%;margin:0 4em"><a href="/wiki/%D0%8B%D0%B5%D0%BB%D0%B8%D1%98%D1%81%D0%BA%D0%B0_%D0%BA%D0%BE%D0%BC%D1%83%D0%BD%D0%B8%D0%BA%D0%B0%D1%86%D0%B8%D1%98%D0%B0" title="Ћелијска комуникација">Ćelijska komunikacija</a>: <a href="/wiki/%D0%A6%D0%B8%D1%82%D0%BE%D0%BA%D0%B8%D0%BD%D0%B8" class="mw-redirect" title="Цитокини">Citokini</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Po familiji</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD" class="mw-redirect" title="Интерлеукин">Interleukin</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <li class="mw-empty-elt"></li></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/%D0%98%D0%9B-1" class="mw-redirect" title="ИЛ-1">IL-1</a> superfamilija</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_1" title="Интерлеукин 1">1</a> (<a href="/wiki/Antagonist_interleukin-1_receptora" title="Antagonist interleukin-1 receptora">1Ra</a>)</li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_18" title="Интерлеукин 18">18</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_33" title="Интерлеукин 33">33</a></li> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">poput <a href="/wiki/%D0%98%D0%9B-6" class="mw-redirect" title="ИЛ-6">IL-6</a>/<a href="/wiki/Glikoprotein_130" title="Glikoprotein 130">gp130</a> koristeći</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6" title="Интерлеукин 6">6</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_11" title="Интерлеукин 11">11</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_27" title="Интерлеукин 27">27</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_30" title="Интерлеукин 30">30</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_31" title="Интерлеукин 31">31</a> (+ne IL <a href="/wiki/Onkostatin_M" title="Onkostatin M">Onkostatin M</a></li> <li><a href="/wiki/Inhibitorni_faktor_leukemije" title="Inhibitorni faktor leukemije">Inhibitorni faktor leukemije</a></li> <li><a href="/wiki/Cilijarni_neurotrofni_faktor" title="Cilijarni neurotrofni faktor">Cilijarni neurotrofni faktor</a></li> <li><a href="/wiki/Kardiotrofin_1" title="Kardiotrofin 1">Kardiotrofin 1</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/%D0%98%D0%9B-10" class="mw-redirect" title="ИЛ-10">IL-10</a> familija</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_10" title="Интерлеукин 10">10</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_19" title="Интерлеукин 19">19</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_20" title="Интерлеукин 20">20</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_22" title="Интерлеукин 22">22</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_24" title="Интерлеукин 24">24</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_26" title="Интерлеукин 26">26</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Interferon_tip_III" title="Interferon tip III">Interferon tip III</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_28" title="Интерлеукин 28">28</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_29" title="Интерлеукин 29">29</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Zajedni%C4%8Dki_gama_lanac" title="Zajednički gama lanac">Zajednički γ-lanac</a> familija</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_2" title="Интерлеукин 2">2</a>/<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_15" title="Интерлеукин 15">15</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_3" title="Интерлеукин 3">3</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_4" title="Интерлеукин 4">4</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_7" title="Интерлеукин 7">7</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_9" title="Интерлеукин 9">9</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_13" title="Интерлеукин 13">13</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_21" title="Интерлеукин 21">21</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/%D0%98%D0%9B-12" class="mw-redirect" title="ИЛ-12">IL-12</a> familija</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_12" title="Интерлеукин 12">12</a> (<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_12%D0%91" title="Интерлеукин 12Б">B</a>)</li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_23" title="Интерлеукин 23">23</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_27" title="Интерлеукин 27">27</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_35" title="Интерлеукин 35">35</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Drugi</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_5" title="Интерлеукин 5">5</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_8" title="Интерлеукин 8">8</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_14" title="Интерлеукин 14">14</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_16" title="Интерлеукин 16">16</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_17" title="Интерлеукин 17">17</a>/<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_25" title="Интерлеукин 25">25</a> (<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_17A" title="Интерлеукин 17A">A</a>)</li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_32" title="Интерлеукин 32">32</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_34" title="Интерлеукин 34">34</a></li></ul> </div></td></tr></tbody></table><div> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Hemokini" title="Hemokini">Hemokini</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">CCL</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <li><a href="/wiki/CCL1" title="CCL1">1</a></li> <li><a href="/wiki/CCL2" title="CCL2">2</a></li> <li><a href="/wiki/Makrofagni_inflamatorni_protein" title="Makrofagni inflamatorni protein">3</a></li> <li><a href="/wiki/CCL4" title="CCL4">4</a></li> <li><a href="/wiki/CCL5" title="CCL5">5</a></li> <li><a href="/wiki/CCL6" title="CCL6">6</a></li> <li><a href="/wiki/CCL7" title="CCL7">7</a></li> <li><a href="/wiki/CCL8" title="CCL8">8</a></li> <li><a href="/wiki/CCL9" title="CCL9">9</a></li> <li><a href="/wiki/CCL9" title="CCL9">10</a></li> <li><a href="/wiki/CCL11" title="CCL11">11</a></li> <li><a href="/wiki/CCL12" title="CCL12">12</a></li> <li><a href="/wiki/CCL13" title="CCL13">13</a></li> <li><a href="/wiki/CCL14" title="CCL14">14</a></li> <li><a href="/wiki/CCL15" title="CCL15">15</a></li> <li><a href="/wiki/CCL16" title="CCL16">16</a></li> <li><a href="/wiki/CCL17" title="CCL17">17</a></li> <li><a href="/wiki/CCL18" title="CCL18">18</a></li> <li><a href="/wiki/CCL19" title="CCL19">19</a></li> <li><a href="/wiki/CCL20" title="CCL20">20</a></li> <li><a href="/wiki/CCL21" title="CCL21">21</a></li> <li><a href="/wiki/CCL22" title="CCL22">22</a></li> <li><a href="/wiki/CCL23" title="CCL23">23</a></li> <li><a href="/wiki/CCL24" title="CCL24">24</a></li> <li><a href="/wiki/CCL25" title="CCL25">25</a></li> <li><a href="/wiki/CCL26" title="CCL26">26</a></li> <li><a href="/wiki/CCL27" title="CCL27">27</a></li> <li><a href="/wiki/CCL28" title="CCL28">28</a></li> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">CXCL</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CXCL1" title="CXCL1">1</a></li> <li><a href="/wiki/CXCL2" title="CXCL2">2</a></li> <li><a href="/wiki/CXCL3" title="CXCL3">3</a></li> <li><a href="/wiki/Trombocit_faktor_4" title="Trombocit faktor 4">4</a></li> <li><a href="/wiki/CXCL5" title="CXCL5">5</a></li> <li><a href="/wiki/CXCL6" title="CXCL6">6</a></li> <li><a href="/wiki/CXCL7" title="CXCL7">7</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_8" title="Интерлеукин 8">8</a></li> <li><a href="/wiki/CXCL9" title="CXCL9">9</a></li> <li><a href="/wiki/CXCL10" title="CXCL10">10</a></li> <li><a href="/wiki/CXCL11" title="CXCL11">11</a></li> <li><a class="mw-selflink selflink">12</a></li> <li><a href="/wiki/CXCL13" title="CXCL13">13</a></li> <li><a href="/wiki/CXCL14" title="CXCL14">14</a></li> <li><a href="/wiki/CXCL15" title="CXCL15">15</a></li> <li><a href="/wiki/CXCL16" title="CXCL16">16</a></li> <li><a href="/wiki/CXCL17" title="CXCL17">17</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">CX3CL</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CX3CL1" title="CX3CL1">1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">XCL</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/XCL1" title="XCL1">1</a></li> <li><a href="/wiki/XCL2" title="XCL2">2</a></li></ul> </div></td></tr></tbody></table><div> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Faktori_nekroze_tumora" title="Faktori nekroze tumora">TNF</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Glavni</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <li><a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">TNF-alfa</a></li> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">TNF (<a href="/wiki/Ligand_(biohemija)" title="Ligand (biohemija)">ligand</a>) superfamilija</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/4-1BB_ligand" title="4-1BB ligand">4-1BB ligand</a></li> <li><a href="/wiki/Faktor_aktivacije_B-%C4%87elija" title="Faktor aktivacije B-ćelija">Faktor aktivacije B-ćelija</a></li> <li><a href="/wiki/Fas_ligand" title="Fas ligand">FAS ligand</a></li> <li><a href="/wiki/Limfotoksin" title="Limfotoksin">Limfotoksin</a></li> <li><a href="/wiki/OX40L" title="OX40L">OX40L</a></li> <li><a href="/wiki/RANKL" title="RANKL">RANKL</a></li> <li><a href="/wiki/TRAIL" title="TRAIL">TRAIL</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Klaster_diferencijacije" title="Klaster diferencijacije">Klaster diferencijacije</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD70" title="CD70">CD70</a></li> <li><a href="/wiki/CD153" title="CD153">CD153</a></li> <li><a href="/wiki/CD154" title="CD154">CD154</a></li></ul> </div></td></tr></tbody></table><div> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Interferon" title="Interferon">Interferon</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Interferon_tip_I" title="Interferon tip I">I</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <li>alfa (<a href="/wiki/Pegilirani_interferon_alfa-2a" title="Pegilirani interferon alfa-2a"> Pegilirani 2a</a></li> <li><a href="/wiki/Pegilirani_interferon_alfa-2b" title="Pegilirani interferon alfa-2b"> Pegilirani 2b</a>), beta (<a href="/wiki/Interferon_beta-1a" title="Interferon beta-1a">1a</a></li> <li><a href="/wiki/Interferon_beta-1b" title="Interferon beta-1b">1b</a>)</li> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Interferon_tip_II" title="Interferon tip II">II</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Interferon-gama" title="Interferon-gama">Gama</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Interferon_tip_III" title="Interferon tip III">III</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_28" title="Интерлеукин 28">IL-28</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_29" title="Интерлеукин 29">IL-29</a></li></ul> </div></td></tr></tbody></table><div> </div></td></tr></tbody></table><div> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Drugi</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Monokin" title="Monokin">Monokin</a></li> <li><a href="/wiki/Limfokin" title="Limfokin">Limfokin</a> (<a href="/wiki/Limfotoksin" title="Limfotoksin">Limfotoksin</a></li> <li><a href="/wiki/Faktor_transfera" title="Faktor transfera">Faktor transfera</a>)</li> <li><a href="/wiki/Faktor_rasta" title="Faktor rasta">Faktor rasta</a></li> <li><a href="/wiki/Hematopoeza" title="Hematopoeza">Hematopoeza</a> (<a href="/wiki/Faktor_stem_%C4%87elija" title="Faktor stem ćelija">Faktor stem ćelija</a></li> <li><a href="/wiki/Faktor_stimulacije_kolonije" title="Faktor stimulacije kolonije">Faktor stimulacije kolonije</a>)</li> <li><a href="/wiki/GPI_(gen)" title="GPI (gen)">Faktor autokrinog motiliteta</a></li> <li><a href="/wiki/Osteopontin" title="Osteopontin">Osteopontin</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Po funkciji</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><i><a href="/wiki/Proinflamatorni_citokin" title="Proinflamatorni citokin">proinflamatorni citokin</a></i> (<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_1" title="Интерлеукин 1">IL-1</a></li> <li><a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">TNF-alfa</a>)</li> <li><a href="/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije"><i>T<sub>h</sub>1</i></a> (<a href="/wiki/Interferon-gama" title="Interferon-gama">INF-gama</a> i <a href="/wiki/Faktor_nekroze_tumora-beta" class="mw-redirect" title="Faktor nekroze tumora-beta">TNF-beta</a>)</li> <li><a href="/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije"><i>T<sub>h</sub>2</i></a> (<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_4" title="Интерлеукин 4">IL-4</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_5" title="Интерлеукин 5">IL-5</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6" title="Интерлеукин 6">IL-6</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_10" title="Интерлеукин 10">IL-10</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_13" title="Интерлеукин 13">IL-13</a>)</li> <li><a href="/wiki/T_pomo%C4%87ne_17_%C4%87elije" title="T pomoćne 17 ćelije"><i>T<sub>h</sub>17</i></a> (<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_17" title="Интерлеукин 17">IL-17</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_22" title="Интерлеукин 22">IL-22</a>)</li></ul> </div></td></tr></tbody></table></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" 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