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href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%9E%D1%82%D0%B2%D0%BE%D1%80%D0%B8_%D0%BD%D0%B0%D0%BB%D0%BE%D0%B3&returnto=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6" title="Иако није обавезно, препоручујемо да отворите налог и пријавите се" class=""><span>Отвори налог</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%9A%D0%BE%D1%80%D0%B8%D1%81%D0%BD%D0%B8%D1%87%D0%BA%D0%B0_%D0%BF%D1%80%D0%B8%D1%98%D0%B0%D0%B2%D0%B0&returnto=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6" title="Иако није обавезно, препоручујемо да се пријавите [o]" accesskey="o" class=""><span>Пријави ме</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out 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href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=sr.wikipedia.org&uselang=sr"><span>Донације</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%9E%D1%82%D0%B2%D0%BE%D1%80%D0%B8_%D0%BD%D0%B0%D0%BB%D0%BE%D0%B3&returnto=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6" title="Иако није обавезно, препоручујемо да отворите налог и пријавите се"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>Отвори налог</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%9A%D0%BE%D1%80%D0%B8%D1%81%D0%BD%D0%B8%D1%87%D0%BA%D0%B0_%D0%BF%D1%80%D0%B8%D1%98%D0%B0%D0%B2%D0%B0&returnto=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6" title="Иако није обавезно, препоручујемо да се пријавите [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>Пријави ме</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"><div id="mw-dismissablenotice-anonplace"></div><script>(function(){var node=document.getElementById("mw-dismissablenotice-anonplace");if(node){node.outerHTML="\u003Cdiv class=\"mw-dismissable-notice\"\u003E\u003Cdiv class=\"mw-dismissable-notice-close\"\u003E[\u003Ca tabindex=\"0\" role=\"button\"\u003Eодбаци\u003C/a\u003E]\u003C/div\u003E\u003Cdiv class=\"mw-dismissable-notice-body\"\u003E\u003C!-- CentralNotice --\u003E\u003Cdiv id=\"localNotice\" data-nosnippet=\"\"\u003E\u003Cdiv class=\"sitenotice\" lang=\"sr\" dir=\"ltr\"\u003E\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #f0f0f0; border-radius:5px; 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href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%A2%D0%B0%D0%BA%D0%BC%D0%B8%D1%87%D0%B5%D1%9A%D0%B5_%D1%83_%D0%BF%D0%B8%D1%81%D0%B0%D1%9A%D1%83_%D1%87%D0%BB%D0%B0%D0%BD%D0%B0%D0%BA%D0%B0/%D0%A3_%D1%81%D0%B2%D0%B5%D1%82%D1%83_%D0%A4%D0%BB%D0%BE%D1%80%D0%B5_%D0%B8_%D0%A4%D0%B0%D1%83%D0%BD%D0%B5\" title=\"Википедија:Такмичење у писању чланака/У свету Флоре и Фауне\"\u003EФлоре и фауне\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EПридружите се \u003Cb\u003E\u003Ca href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%A3%D1%80%D0%B5%D1%92%D0%B8%D0%B2%D0%B0%D1%87%D0%BA%D0%B8_%D0%BC%D0%B0%D1%80%D0%B0%D1%82%D0%BE%D0%BD_%D0%92%D0%B8%D0%BA%D0%B8_%D0%B2%D0%BE%D0%BB%D0%B8_%D1%98%D0%B0%D0%B2%D0%BD%D1%83_%D1%83%D0%BC%D0%B5%D1%82%D0%BD%D0%BE%D1%81%D1%82_%D0%B8_%D0%B3%D1%80%D0%BE%D0%B1%D0%BD%D0%B0_%D0%BE%D0%B1%D0%B5%D0%BB%D0%B5%D0%B6%D1%98%D0%B0_2024.\" title=\"Википедија:Уређивачки маратон Вики воли јавну уметност и гробна обележја 2024.\"\u003EУређивачком маратону Вики воли јавну уметност и гробна обележја 2024\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EУчествујте у \u003Cb\u003E\u003Ca href=\"https://sr.wikiquote.org/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D1%86%D0%B8%D1%82%D0%B0%D1%82:%D0%9A%D0%B0%D0%BC%D0%BF%D0%B0%D1%9A%D0%B0_SheSaid_2024\" class=\"extiw\" title=\"q:Викицитат:Кампања SheSaid 2024\"\u003Eкампањи писања цитата значајних жена\u003C/a\u003E\u003C/b\u003E на Викицитату.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EПридружите се \u003Cb\u003E\u003Ca href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%90%D0%BA%D1%86%D0%B8%D1%98%D0%B0_%D0%BF%D1%80%D0%BE%D1%88%D0%B8%D1%80%D0%B8%D0%B2%D0%B0%D1%9A%D0%B0_%D0%BA%D0%BB%D0%B8%D1%86%D0%B0\" title=\"Википедија:Акција проширивања клица\"\u003Eакцији проширивања клица\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E";}}());</script></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Сајт"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Садржај" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Садржај</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">помери на страну</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">сакриј</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Почетак</div> </a> </li> <li id="toc-Функција" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Функција"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Функција</span> </div> </a> <ul id="toc-Функција-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Рецептор" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Рецептор"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Рецептор</span> </div> </a> <ul id="toc-Рецептор-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Интеракције" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Интеракције"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Интеракције</span> </div> </a> <ul id="toc-Интеракције-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Улога_код_болести" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Улога_код_болести"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Улога код болести</span> </div> </a> <ul id="toc-Улога_код_болести-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Референце" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Референце"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Референце</span> </div> </a> <ul id="toc-Референце-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Литература" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Литература"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Литература</span> </div> </a> <ul id="toc-Литература-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Спољашње_везе" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Спољашње_везе"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Спољашње везе</span> </div> </a> <ul id="toc-Спољашње_везе-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Садржај" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Прикажи/сакриј садржај" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Прикажи/сакриј садржај</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Интерлеукин 6</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Чланак на другим језицима. Доступан на: 23" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-23" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">23 језика</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A5%D9%86%D8%AA%D8%B1%D9%84%D9%88%D9%83%D9%8A%D9%86_6" title="إنترلوكين 6 — арапски" lang="ar" hreflang="ar" data-title="إنترلوكين 6" data-language-autonym="العربية" data-language-local-name="арапски" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Interleukin-6" title="Interleukin-6 — индонежански" lang="id" hreflang="id" data-title="Interleukin-6" data-language-autonym="Bahasa Indonesia" data-language-local-name="индонежански" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Interleukin_6" title="Interleukin 6 — малајски" lang="ms" hreflang="ms" data-title="Interleukin 6" data-language-autonym="Bahasa Melayu" data-language-local-name="малајски" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Interleucina-6" title="Interleucina-6 — каталонски" lang="ca" hreflang="ca" data-title="Interleucina-6" data-language-autonym="Català" data-language-local-name="каталонски" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/IL6" title="IL6 — велшки" lang="cy" hreflang="cy" data-title="IL6" data-language-autonym="Cymraeg" data-language-local-name="велшки" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Interleukin-6" title="Interleukin-6 — чешки" lang="cs" hreflang="cs" data-title="Interleukin-6" data-language-autonym="Čeština" data-language-local-name="чешки" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Interleukin-6" title="Interleukin-6 — немачки" lang="de" hreflang="de" data-title="Interleukin-6" data-language-autonym="Deutsch" data-language-local-name="немачки" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Interleukin_6" title="Interleukin 6 — енглески" lang="en" hreflang="en" data-title="Interleukin 6" data-language-autonym="English" data-language-local-name="енглески" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Interleucina-6" title="Interleucina-6 — шпански" lang="es" hreflang="es" data-title="Interleucina-6" data-language-autonym="Español" data-language-local-name="шпански" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A7%DB%8C%D9%86%D8%AA%D8%B1%D9%84%D9%88%DA%A9%DB%8C%D9%86_%DB%B6" title="اینترلوکین ۶ — персијски" lang="fa" hreflang="fa" data-title="اینترلوکین ۶" data-language-autonym="فارسی" data-language-local-name="персијски" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Interleukine_6" title="Interleukine 6 — француски" lang="fr" hreflang="fr" data-title="Interleukine 6" data-language-autonym="Français" data-language-local-name="француски" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Interleucina_6" title="Interleucina 6 — галицијски" lang="gl" hreflang="gl" data-title="Interleucina 6" data-language-autonym="Galego" data-language-local-name="галицијски" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Interleuchina_6" title="Interleuchina 6 — италијански" lang="it" hreflang="it" data-title="Interleuchina 6" data-language-autonym="Italiano" data-language-local-name="италијански" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%A4%E3%83%B3%E3%82%BF%E3%83%BC%E3%83%AD%E3%82%A4%E3%82%AD%E3%83%B3-6" title="インターロイキン-6 — јапански" lang="ja" hreflang="ja" data-title="インターロイキン-6" data-language-autonym="日本語" data-language-local-name="јапански" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%9D%B8%ED%84%B0%EB%A3%A8%ED%82%A8_6" title="인터루킨 6 — корејски" lang="ko" hreflang="ko" data-title="인터루킨 6" data-language-autonym="한국어" data-language-local-name="корејски" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Interleik%C4%ABns_6" title="Interleikīns 6 — летонски" lang="lv" hreflang="lv" data-title="Interleikīns 6" data-language-autonym="Latviešu" data-language-local-name="летонски" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/IL-6" title="IL-6 — холандски" lang="nl" hreflang="nl" data-title="IL-6" data-language-autonym="Nederlands" data-language-local-name="холандски" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Interleukina_6" title="Interleukina 6 — пољски" lang="pl" hreflang="pl" data-title="Interleukina 6" data-language-autonym="Polski" data-language-local-name="пољски" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Interleucina-6" title="Interleucina-6 — португалски" lang="pt" hreflang="pt" data-title="Interleucina-6" data-language-autonym="Português" data-language-local-name="португалски" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D0%B9%D0%BA%D0%B8%D0%BD_6" title="Интерлейкин 6 — руски" lang="ru" hreflang="ru" data-title="Интерлейкин 6" data-language-autonym="Русский" data-language-local-name="руски" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Interleukin_6" title="Interleukin 6 — српскохрватски" lang="sh" hreflang="sh" data-title="Interleukin 6" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="српскохрватски" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%86%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D0%B9%D0%BA%D1%96%D0%BD-6" title="Інтерлейкін-6 — украјински" lang="uk" hreflang="uk" data-title="Інтерлейкін-6" data-language-autonym="Українська" data-language-local-name="украјински" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E7%99%BD%E7%BB%86%E8%83%9E%E4%BB%8B%E7%B4%A0-6" title="白细胞介素-6 — кинески" lang="zh" hreflang="zh" data-title="白细胞介素-6" data-language-autonym="中文" data-language-local-name="кинески" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q412889#sitelinks-wikipedia" title="Уреди међујезичке везе" class="wbc-editpage">Уреди везе</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Именски 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hreflang="sr-Cyrl"><span>Ћирилица</span></a></li><li id="ca-varlang-2" class="ca-variants-sr-Latn mw-list-item"><a href="/sr-el/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6" lang="sr-Latn" hreflang="sr-Latn"><span>Latinica</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Погледи"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6"><span>Читај</span></a></li><li id="ca-ve-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&veaction=edit" title="Уредите ову страницу [v]" accesskey="v"><span>Уреди</span></a></li><li id="ca-edit" class="collapsible vector-tab-noicon mw-list-item"><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&action=edit" title="Уредите изворни код ове странице [e]" accesskey="e"><span>Уреди извор</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&action=history" title="Историја [h]" accesskey="h"><span>Историја</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Алатке странице"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Алатке" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Алатке</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Алатке</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">помери на страну</button> <button class="vector-pinnable-header-toggle-button 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class="mw-list-item"><a href="/w/index.php?title=%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:DownloadAsPdf&page=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&action=show-download-screen"><span>Преузми у PDF-у</span></a></li><li id="t-print" class="mw-list-item"><a href="javascript:print();" rel="alternate" title="Одштампајте ову страницу [p]" accesskey="p"><span>Одштампај</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> На другим пројектима </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q412889" title="Веза ка ставци на спремишту података [g]" accesskey="g"><span>Ставка на Википодацима</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Алатке странице"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Изглед"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Изглед</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">помери на страну</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">сакриј</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">С Википедије, слободне енциклопедије</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="sr" dir="ltr"><table align="right" border="0" style="background:#fff; width:280px;" class="plainlinks"> <tbody><tr><td></td></tr></tbody></table><style data-mw-deduplicate="TemplateStyles:r28440203">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}body.skin-minerva .mw-parser-output .infobox-header,body.skin-minerva .mw-parser-output .infobox-subheader,body.skin-minerva .mw-parser-output .infobox-above,body.skin-minerva .mw-parser-output .infobox-title,body.skin-minerva .mw-parser-output .infobox-image,body.skin-minerva .mw-parser-output .infobox-full-data,body.skin-minerva .mw-parser-output .infobox-below{text-align:center}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox"><tbody><tr><th colspan="4" class="infobox-above">Интерлеукин 6 (интерлеукин, бета 2)</th></tr><tr><td colspan="4" class="infobox-image"> <span class="mw-image-border" typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:IL6_Crystal_Structure.rsh.png" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e7/IL6_Crystal_Structure.rsh.png/250px-IL6_Crystal_Structure.rsh.png" decoding="async" width="250" height="281" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e7/IL6_Crystal_Structure.rsh.png/375px-IL6_Crystal_Structure.rsh.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e7/IL6_Crystal_Structure.rsh.png/500px-IL6_Crystal_Structure.rsh.png 2x" data-file-width="668" data-file-height="750" /></a></span><div class="infobox-caption"><a href="/wiki/Proteinska_banka_podataka" title="Proteinska banka podataka">ПДБ</a> приказ структуре <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1ALU">1ALU</a></span>.</div></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Доступне структуре</th></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1alu">1alu</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1il6">1il6</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1p9m">1p9m</a></span>, <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2il6">2il6</a></span></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Идентификатори</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Organizacija_za_ljudski_genom" title="Organizacija za ljudski genom">Симболи</a></th><td colspan="3" class="infobox-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=6018">IL6</a>; HGF; BSF2; HSF; IFNB2; IL-6</span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Вањски ИД</th><td colspan="3" class="infobox-data" style="background-color: #eee"> <span class="plainlinks"><a href="/wiki/%D0%9C%D0%B5%D0%BD%D0%B4%D0%B5%D0%BB%D0%BE%D0%B2%D1%81%D0%BA%D0%BE_%D0%BD%D0%B0%D1%81%D0%BB%D0%B5%D1%92%D0%B8%D0%B2%D0%B0%D1%9A%D0%B5_%D0%BA%D0%BE%D0%B4_%D1%87%D0%BE%D0%B2%D0%B5%D0%BA%D0%B0" title="Менделовско наслеђивање код човека">OMIM</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147620">147620 </a></span> <span class="plainlinks"><a href="/wiki/%D0%98%D0%BD%D1%84%D0%BE%D1%80%D0%BC%D0%B0%D1%82%D0%B8%D0%BA%D0%B0_%D0%BC%D0%B8%D1%88%D1%98%D0%B5%D0%B3_%D0%B3%D0%B5%D0%BD%D0%BE%D0%BC%D0%B0" title="Информатика мишјег генома">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:96559">96559 </a></span> <span class="plainlinks"><a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=502">502 </a></span> <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=3569">IL6 Gene</a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <table class="collapsible collapsed" style="border: none; padding: 0; margin: 0; width: 100%; text-align: left"> <tbody><tr style="background-color: #ddd; text-align: center"> <th colspan="2"><a href="/wiki/Ontologija_gena" title="Ontologija gena">Онтологија гена</a></th> </tr> <tr> <th style="background-color: #c3fdb8">Молекулска функција</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005125">активност цитокина</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005138">везивање за интерлеукин-6 рецептор</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005515">везивање за протеине</a></span><br /></td> </tr> <tr> <th style="background-color: #c3fdb8">Ћелијска компонента</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005576">екстрацелуларни регион</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005615">екстрацелуларни простор</a></span><br /></td> </tr> <tr> <th style="background-color: #c3fdb8">Биолошки процес</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0001781">неутрофилна апоптоза</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0006953">респонс акутне-фазе</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0006959">имуни респонс глодара</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007166">пренос сигнала везан за рецепторе на ћелијској порвршини</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007267">интерћелијска сигнализација</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0008284">позитивна регулација ћелијске пролиферације</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0008285">негативна регулација ћелијске пролиферације</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0043066">негативна регулација апоптозе</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0045079">негативна регулација биосинтетичког процеса хемокина</a></span><br /></td> </tr> </tbody></table></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Преглед РНК изражавања</th></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PBB_GE_IL6_205207_at.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c3/PBB_GE_IL6_205207_at.png/250px-PBB_GE_IL6_205207_at.png" decoding="async" width="250" height="132" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/c/c3/PBB_GE_IL6_205207_at.png 1.5x" data-file-width="255" data-file-height="135" /></a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.gnf.org/gene/3569/Додатни">подаци</a></span></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Ортолози</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Врста</th><td class="infobox-data infobox-data-a"> <b>Човек</b></td><td class="infobox-data infobox-data-b"> <b>Миш</b></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Entrez" title="Entrez">Ентрез</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=3569&rn=1">3569</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=16193&rn=1">16193</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Ensembl" title="Ensembl">Eнсембл</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000136244;db=core">ENSG00000136244</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000025746;db=core">ENSMUSG00000025746</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/UniProt" title="UniProt">UниПрот</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/P05231">P05231</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/Q0PMN1">Q0PMN1</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Реф. Секв. (иРНК)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_000600">NM_000600</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_031168">NM_031168</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Реф. Секв. (протеин)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_000591">NP_000591</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_112445">NP_112445</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Локација (УЦСЦ)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg18&position=chr7:22732028-22738091">Chr 7:<br />22.73 - 22.74 Mb</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm8&position=chr5:30343948-30350755">Chr 5:<br />30.34 - 30.35 Mb</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/PubMed" title="PubMed">ПубМед</a> претрага</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=3569">[1]</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=16193">[2]</a></span></td></tr></tbody></table> <p><b>Интерлеукин 6</b> (ИЛ-6) је <a href="/wiki/%D0%9F%D1%80%D0%BE%D1%82%D0%B5%D0%B8%D0%BD" title="Протеин">протеин</a> који је код људи кодиран <a href="/wiki/%D0%93%D0%B5%D0%BD" title="Ген">геном</a> <i>ИЛ6.</i><sup id="cite_ref-pmid3294161_1-0" class="reference"><a href="#cite_note-pmid3294161-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>ИЛ-6 је <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD%D0%B8" title="Интерлеукини">интерлеукин</a> који може да дејствује као проинфламаторни и антиинфламаторни <a href="/wiki/%D0%A6%D0%B8%D1%82%D0%BE%D0%BA%D0%B8%D0%BD%D0%B8" class="mw-redirect" title="Цитокини">цитокин</a>. Он се излучује из <a href="/wiki/T_%C4%87elija" class="mw-redirect" title="T ćelija">T ћелија</a> и <a href="/wiki/%D0%9C%D0%B0%D0%BA%D1%80%D0%BE%D1%84%D0%B0%D0%B3" title="Макрофаг">макрофага</a>. Овај цитокиин иницира имуни одговор на трауму, посебно опекотине и друге оштете ткива које доводе до инфламације.<sup id="cite_ref-KubyImmunology6th_3-0" class="reference"><a href="#cite_note-KubyImmunology6th-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> За ИЛ-6 је било показано код мишева, да је он у погледу одговора домаћина на стране патогене неопходан за отпорност против бактерије <i><a href="/wiki/%D0%9F%D0%BD%D0%B5%D1%83%D0%BC%D0%BE%D0%BA%D0%BE%D0%BA%D0%B5" title="Пнеумококе">Streptococcus pneumoniae</a></i>.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> ИЛ-6 је исто тако „миокин," цитокин произведен у мишићима, и његова количина је повишена услед мишићних контракција.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> Његова концентрације је значајно повишена у току тренинга, и он претходи појави других цитокина у циркулацији. За њега се мисли да дејствује попут хормона који мобилизује екстрацелуларне супстанце и/или мења испоруку супстрата током физичких активности. Додатно, <a href="/w/index.php?title=%D0%9E%D1%81%D1%82%D0%B5%D0%BE%D0%B1%D0%BB%D0%B0%D1%81%D1%82&action=edit&redlink=1" class="new" title="Остеобласт (страница не постоји)">остеобласти</a> излучују ИЛ-6 да би стимулисали формирање <a href="/wiki/Osteoclast" class="mw-redirect" title="Osteoclast">остеокласта</a>. <a href="/w/index.php?title=%D0%8B%D0%B5%D0%BB%D0%B8%D1%98%D0%B5_%D0%B3%D0%BB%D0%B0%D1%82%D0%BA%D0%B8%D1%85_%D0%BC%D0%B8%D1%88%D0%B8%D1%9B%D0%B0&action=edit&redlink=1" class="new" title="Ћелије глатких мишића (страница не постоји)">Ћелије глатких мишића</a> у <a href="/w/index.php?title=Tunica_media&action=edit&redlink=1" class="new" title="Tunica media (страница не постоји)"><i>tunica media</i></a> многих крвних судова такође производе ИЛ-6 као проинфламаторни <a href="/wiki/%D0%A6%D0%B8%D1%82%D0%BE%D0%BA%D0%B8%D0%BD%D0%B8" class="mw-redirect" title="Цитокини">цитокин</a>. Улога ИЛ-6 цитокина као антиинфламаторног агента је посредована путем његових инхибиторних ефеката на <a href="/wiki/TNF-alfa" class="mw-redirect" title="TNF-alfa">ТНФ-алфа</a> и <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_1" title="Интерлеукин 1">ИЛ-1</a>, и активацију <a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_%D1%80%D0%B5%D1%86%D0%B5%D0%BF%D1%82%D0%BE%D1%80_1_%D0%B0%D0%BB%D1%84%D0%B0&action=edit&redlink=1" class="new" title="Интерлеукин рецептор 1 алфа (страница не постоји)">ИЛ-1Ра</a> и <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_1" title="Интерлеукин 1">ИЛ-10</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Функција"><span id=".D0.A4.D1.83.D0.BD.D0.BA.D1.86.D0.B8.D1.98.D0.B0"></span>Функција</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&veaction=edit&section=1" title="Уредите одељак „Функција”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&action=edit&section=1" title="Уреди извор одељка: Функција"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>ИЛ-6 је један од најважнијих посредника <a href="/wiki/Groznica" title="Groznica">грознице</a> и <a href="/wiki/%D0%9F%D1%80%D0%BE%D1%82%D0%B5%D0%B8%D0%BD%D0%B8_%D0%B0%D0%BA%D1%83%D1%82%D0%BD%D0%B5_%D1%84%D0%B0%D0%B7%D0%B5" title="Протеини акутне фазе">акутне фазе одзива</a>. Он има способност пролажења кроз <a href="/wiki/%D0%9A%D1%80%D0%B2%D0%BD%D0%BE-%D0%BC%D0%BE%D0%B6%D0%B4%D0%B0%D0%BD%D0%B0_%D0%B1%D0%B0%D1%80%D0%B8%D1%98%D0%B5%D1%80%D0%B0" title="Крвно-мождана баријера">крвно-мождану баријеру</a> и иницирања <a href="/wiki/PGE2" class="mw-redirect" title="PGE2">ПГE2</a> синтезе у <a href="/wiki/%D0%A5%D0%B8%D0%BF%D0%BE%D1%82%D0%B0%D0%BB%D0%B0%D0%BC%D1%83%D1%81" title="Хипоталамус">хипоталамусу</a>, чиме се мења температура тела. ИЛ-6 могу излучити <a href="/wiki/%D0%9C%D0%B0%D0%BA%D1%80%D0%BE%D1%84%D0%B0%D0%B3" title="Макрофаг">макрофаге</a> у одговору на специфичне микробне молекуле, што се назива <a href="/wiki/Patogen" title="Patogen">патоген</a> асоцирани молекулски образац (<a href="/w/index.php?title=%D0%9F%D0%90%D0%9C%D0%9F&action=edit&redlink=1" class="new" title="ПАМП (страница не постоји)">ПАМП</a>). ПАМП молекули се везују за веома важну групу детекционих молекула <a href="/w/index.php?title=%D0%A3%D1%80%D0%BE%D1%92%D0%B5%D0%BD%D0%B8_%D0%B8%D0%BC%D1%83%D0%BD%D1%81%D0%BA%D0%B8_%D1%81%D0%B8%D1%81%D1%82%D0%B5%D0%BC&action=edit&redlink=1" class="new" title="Урођени имунски систем (страница не постоји)">урођеног имунског система</a>, званих рецептори препознавања образаца (<a href="/w/index.php?title=%D0%9F%D0%A0%D0%A0&action=edit&redlink=1" class="new" title="ПРР (страница не постоји)">ПРР</a>), међу којима су и <a href="/wiki/Toli%C4%8Dni_receptor" title="Tolični receptor">ТЛР</a> рецептори. Они су присутни на ћелијској површини и интрацелуларним компартманима, и они индукују интрацелуларне сигналне каскаде које доводе до продукције инфламаторних цитокина. ИЛ-6 је исто тако есенцијалан за развој <a href="/w/index.php?title=Hibridoma&action=edit&redlink=1" class="new" title="Hibridoma (страница не постоји)">hibridoma</a>, и налази се у многим суплементарним медијумима за клонирање као што је <a href="/w/index.php?title=BriClone&action=edit&redlink=1" class="new" title="BriClone (страница не постоји)">BriClone<sup>®</sup></a>. ИЛ-6 инхибитори (укључујући <a href="/wiki/%D0%95%D1%81%D1%82%D1%80%D0%BE%D0%B3%D0%B5%D0%BD" title="Естроген">естроген</a>) се користе у третману постменопозне <a href="/wiki/Osteoporoza" title="Osteoporoza">остеопорозе</a>. ИЛ-6 исто производе <a href="/wiki/%D0%90%D0%B4%D0%B8%D0%BF%D0%BE%D1%86%D0%B8%D1%82" title="Адипоцит">адипоцити</a>, и за то се мисли да је разлог повишеног <a href="/wiki/CRP" class="mw-disambig" title="CRP">ЦРП</a> нивоа код гојазних особа. У једног студији из <a href="/wiki/2009" title="2009">2009</a>. године са интраназално администрираним ИЛ-6, показано је да он побољшава сан-асоцирану <a href="/wiki/%D0%9A%D0%BE%D0%BD%D1%81%D0%BE%D0%BB%D0%B8%D0%B4%D0%B0%D1%86%D0%B8%D1%98%D0%B0_%D0%BC%D0%B5%D0%BC%D0%BE%D1%80%D0%B8%D1%98%D0%B5" title="Консолидација меморије">консолидацију</a> емотивних меморија.<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Рецептор"><span id=".D0.A0.D0.B5.D1.86.D0.B5.D0.BF.D1.82.D0.BE.D1.80"></span>Рецептор</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&veaction=edit&section=2" title="Уредите одељак „Рецептор”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&action=edit&section=2" title="Уреди извор одељка: Рецептор"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>ИЛ-6 сигнализира кроз рецепторе на ћелијској површини. ИЛ-6 рецептор је <a href="/w/index.php?title=%D0%A2%D0%B8%D0%BF_I_%D1%86%D0%B8%D1%82%D0%BE%D0%BA%D0%B8%D0%BD_%D1%80%D0%B5%D1%86%D0%B5%D0%BF%D1%82%D0%BE%D1%80&action=edit&redlink=1" class="new" title="Тип I цитокин рецептор (страница не постоји)">тип I цитокин рецепторски</a> комплекс који се састоји од <a href="/wiki/Ligand_(biohemija)" title="Ligand (biohemija)">лиганд</a>-везујућег ИЛ-6Рα ланца (<a href="/wiki/Klaster_diferencijacije" title="Klaster diferencijacije">ЦД126</a>), и сигнал-преносеће компоненте <a href="/wiki/Gp130" class="mw-redirect" title="Gp130">гп130</a> (исто познате као ЦД130). ЦД130 је заједнички сигнал преносилац за неколико цитокина међу којима су <a href="/wiki/Inhibitorni_faktor_leukemije" title="Inhibitorni faktor leukemije">Инхибиторни фактор леукемије</a> (ЛИФ), <a href="/wiki/Cilijarni_neurotrofni_faktor" title="Cilijarni neurotrofni faktor">цилијарни неуротрофни фактор</a>, <a href="/wiki/Onkostatin_M" title="Onkostatin M">онкостатин M</a>, <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_11" title="Интерлеукин 11">ИЛ-11</a> и <a href="/wiki/Kardiotrofin_1" title="Kardiotrofin 1">кардиотрофин 1</a>, и он је скоро свеприсутно изражен у већини ткива, док је ЦД126 изражавање ограничено на одређена ткива. ИЛ-6 интеракција са његовим рецептором, подстиче гп130 и ИЛ-6Р <a href="/wiki/%D0%9F%D1%80%D0%BE%D1%82%D0%B5%D0%B8%D0%BD" title="Протеин">протеине</a> да формирају комплекс, чиме се активира рецептор. Ови комплекси приближавају <a href="/wiki/Intracelularni" title="Intracelularni">интрацелуларне</a> гп130 регионе чиме се иницира каскада преноса сигнала кроз одређене <a href="/w/index.php?title=%D0%A2%D1%80%D0%B0%D0%BD%D1%81%D0%BA%D1%80%D0%B8%D0%BF%D1%86%D0%B8%D0%BE%D0%BD%D0%B8_%D1%84%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D0%B8&action=edit&redlink=1" class="new" title="Транскрипциони фактори (страница не постоји)">транскрипционе факторе</a>, Јанус киназе (<a href="/w/index.php?title=JAK&action=edit&redlink=1" class="new" title="JAK (страница не постоји)">JAKs</a>) и <a href="/w/index.php?title=CTAT&action=edit&redlink=1" class="new" title="CTAT (страница не постоји)">CTAT</a> факторе.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>ИЛ-6 је вероватно најбоље студиран од свих цитокина који користе гп130 у њиховим сигналним комплексима. Други цитокини који преносе сигнал кроз рецептор који садржи гп130 су <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_11" title="Интерлеукин 11">Интерлеукин 11</a> (ИЛ-11), <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_27" title="Интерлеукин 27">Интерлеукин 27</a> (ИЛ-27), <a href="/wiki/Cilijarni_neurotrofni_faktor" title="Cilijarni neurotrofni faktor">цилијарни неуротрофни фактор</a> (ЦНТФ), <a href="/wiki/Kardiotrofin_1" title="Kardiotrofin 1">кардиотрофин 1</a> (ЦТ-1), <a href="/w/index.php?title=CLCF1&action=edit&redlink=1" class="new" title="CLCF1 (страница не постоји)">кардиотрофин--сличан цитокин</a> (ЦЛЦ), <a href="/wiki/Inhibitorni_faktor_leukemije" title="Inhibitorni faktor leukemije">Инхибиторни фактор леукемије</a> (ЛИФ), <a href="/wiki/Onkostatin_M" title="Onkostatin M">онкостатин M</a> (ОСМ), <a href="/w/index.php?title=%D0%9A%D0%B0%D0%BF%D0%BE%D1%88%D0%B8%D1%98%D0%B5%D0%B2_%D1%81%D0%B0%D1%80%D0%BA%D0%BE%D0%BC-%D0%B0%D1%81%D0%BE%D1%86%D0%B8%D1%80%D0%B0%D0%BD%D0%B8_%D1%85%D0%B5%D1%80%D0%BF%D0%B5%D1%81%D0%B2%D0%B8%D1%80%D1%83%D1%81&action=edit&redlink=1" class="new" title="Капошијев сарком-асоцирани херпесвирус (страница не постоји)">Капошијев сарком-асоцирани херпесвирус</a> интерлеукину 6 сличан <a href="/wiki/%D0%9F%D1%80%D0%BE%D1%82%D0%B5%D0%B8%D0%BD" title="Протеин">протеин</a> (<a href="/w/index.php?title=%D0%9A%D0%A1%D0%A5%D0%92-%D0%98%D0%9B6&action=edit&redlink=1" class="new" title="КСХВ-ИЛ6 (страница не постоји)">КСХВ-ИЛ6</a>).<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> Ови цитокини се нормално зову <i>ИЛ-6 слични</i> или <i>гп130 користећи</i> цитокини.<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p><p>Поред рецептора везаних за мембрану, растворни облик ИЛ-6Р (<a href="/w/index.php?title=%D0%A1%D0%98%D0%9B-6%D0%A0&action=edit&redlink=1" class="new" title="СИЛ-6Р (страница не постоји)">сИЛ-6Р</a>) је био пречишћен из људског серума и урина. Многе нервне ћелије су неодзивне на стимулацију само са ИЛ-6, али њихова <a href="/wiki/%D0%8B%D0%B5%D0%BB%D0%B8%D1%98%D1%81%D0%BA%D0%B0_%D0%B4%D0%B5%D0%BE%D0%B1%D0%B0" title="Ћелијска деоба">диференцијација</a> и опстанак може бити посредован кроз сИЛ-6Р акције. сИЛ-6R/ИЛ-6 комплекс може да стимулише излазак неурита и да помогне опстанку неурона, и из тих разлога може бити важна за регенерацију нерва путем ремијелинације. </p> <div class="mw-heading mw-heading2"><h2 id="Интеракције"><span id=".D0.98.D0.BD.D1.82.D0.B5.D1.80.D0.B0.D0.BA.D1.86.D0.B8.D1.98.D0.B5"></span>Интеракције</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&veaction=edit&section=3" title="Уредите одељак „Интеракције”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&action=edit&section=3" title="Уреди извор одељка: Интеракције"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>За интерлеукин 6 је било показано да формира <a href="/wiki/Protein-protein_interakcija" class="mw-redirect" title="Protein-protein interakcija">интеракцију</a> са <a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD-6_%D1%80%D0%B5%D1%86%D0%B5%D0%BF%D1%82%D0%BE%D1%80&action=edit&redlink=1" class="new" title="Интерлеукин-6 рецептор (страница не постоји)">интерлеукин-6 рецептором</a><sup id="cite_ref-pmid14557255_10-0" class="reference"><a href="#cite_note-pmid14557255-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid12643274_11-0" class="reference"><a href="#cite_note-pmid12643274-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid2788034_12-0" class="reference"><a href="#cite_note-pmid2788034-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> у <a href="/wiki/Glikoprotein_130" title="Glikoprotein 130">гликопротеином 130</a>.<sup id="cite_ref-pmid15989626_13-0" class="reference"><a href="#cite_note-pmid15989626-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Улога_код_болести"><span id=".D0.A3.D0.BB.D0.BE.D0.B3.D0.B0_.D0.BA.D0.BE.D0.B4_.D0.B1.D0.BE.D0.BB.D0.B5.D1.81.D1.82.D0.B8"></span>Улога код болести</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&veaction=edit&section=4" title="Уредите одељак „Улога код болести”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&action=edit&section=4" title="Уреди извор одељка: Улога код болести"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>ИЛ-6 је релевантан у многим процесима болести као што су <a href="/wiki/%D0%A8%D0%B5%D1%9B%D0%B5%D1%80%D0%BD%D0%B0_%D0%B1%D0%BE%D0%BB%D0%B5%D1%81%D1%82" title="Шећерна болест">дијабетис</a>,<sup id="cite_ref-pmid16306329_14-0" class="reference"><a href="#cite_note-pmid16306329-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> <a href="/wiki/%D0%90%D1%82%D0%B5%D1%80%D0%BE%D1%81%D0%BA%D0%BB%D0%B5%D1%80%D0%BE%D0%B7%D0%B0" title="Атеросклероза">атеросклероза</a>,<sup id="cite_ref-pmid17684929_15-0" class="reference"><a href="#cite_note-pmid17684929-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> <a href="/wiki/%D0%9B%D1%83%D0%BF%D1%83%D1%81" title="Лупус">лупус</a>,<sup id="cite_ref-pmid15230289_16-0" class="reference"><a href="#cite_note-pmid15230289-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> <a href="/wiki/Karcinom_prostate" class="mw-redirect" title="Karcinom prostate">рак простате</a>,<sup id="cite_ref-pmid11312117_17-0" class="reference"><a href="#cite_note-pmid11312117-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> и <a href="/wiki/%D0%A0%D0%B5%D1%83%D0%BC%D0%B0%D1%82%D0%BE%D0%B8%D0%B4%D0%BD%D0%B8_%D0%B0%D1%80%D1%82%D1%80%D0%B8%D1%82%D0%B8%D1%81" title="Реуматоидни артритис">реуматоидни артритис</a>.<sup id="cite_ref-pmid16582692_18-0" class="reference"><a href="#cite_note-pmid16582692-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> Пацијенти са напредним/<a href="/w/index.php?title=%D0%9C%D0%B5%D1%82%D0%B0%D1%81%D1%82%D0%B0%D1%82%D0%B8%D1%87%D0%BA%D0%B8_%D1%82%D1%83%D0%BC%D0%BE%D1%80&action=edit&redlink=1" class="new" title="Метастатички тумор (страница не постоји)">метастатичким тумором</a> имају повишене ИЛ-6 нивое у крви.<sup id="cite_ref-urlMedscape.com_Log_In_19-0" class="reference"><a href="#cite_note-urlMedscape.com_Log_In-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> Из ових разлога постоји интерест за развијање <a href="/w/index.php?title=%D0%90%D0%BD%D1%82%D0%B8-%D0%98%D0%9B-6&action=edit&redlink=1" class="new" title="Анти-ИЛ-6 (страница не постоји)">анти-ИЛ-6</a> агената као терапија против већине од ових болести.<sup id="cite_ref-pmid16083340_20-0" class="reference"><a href="#cite_note-pmid16083340-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid16899109_21-0" class="reference"><a href="#cite_note-pmid16899109-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> Прва таква терапија је <a href="/wiki/Tocilizumab" title="Tocilizumab">тоцилизумаб</a> који је одобрен за <a href="/wiki/%D0%A0%D0%B5%D1%83%D0%BC%D0%B0%D1%82%D0%BE%D0%B8%D0%B4%D0%BD%D0%B8_%D0%B0%D1%80%D1%82%D1%80%D0%B8%D1%82%D0%B8%D1%81" title="Реуматоидни артритис">реуматоидни артритис</a>. <a href="/w/index.php?title=A%D0%9B%D0%94518&action=edit&redlink=1" class="new" title="AЛД518 (страница не постоји)">AЛД518</a> је у клиничким испитивањима. </p> <div class="mw-heading mw-heading2"><h2 id="Референце"><span id=".D0.A0.D0.B5.D1.84.D0.B5.D1.80.D0.B5.D0.BD.D1.86.D0.B5"></span>Референце</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&veaction=edit&section=5" title="Уредите одељак „Референце”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&action=edit&section=5" title="Уреди извор одељка: Референце"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r28440201">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width reflist-columns-2"> <ol class="references"> <li id="cite_note-pmid3294161-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid3294161_1-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Ferguson-Smith AC, Chen YF, Newman MS, May LT, Sehgal PB, Ruddle FH (1988). „Regional localization of the interferon-beta 2/B-cell stimulatory factor 2/hepatocyte stimulating factor gene to human chromosome 7p15-p21”. <i>Genomics</i>. <b>2</b> (3): 203—8. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/3294161">3294161</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Regional+localization+of+the+interferon-beta+2%2FB-cell+stimulatory+factor+2%2Fhepatocyte+stimulating+factor+gene+to+human+chromosome+7p15-p21&rft.au=Chen%2C+YF&rft.au=May%2C+LT&rft.au=Newman%2C+MS&rft.au=Ruddle%2C+FH&rft.au=Sehgal%2C+PB&rft.aufirst=AC&rft.aulast=Ferguson-Smith&rft.date=1988&rft.genre=article&rft.issue=3&rft.jtitle=Genomics&rft.pages=203-8&rft.volume=2&rft_id=info%3Apmid%2F3294161&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><cite class="citation book">Mire-Sluis, Anthony R.; Thorpe, Robin, ур. (1998). <a rel="nofollow" class="external text" href="http://www.sciencedirect.com/science/book/9780124983403"><i>Cytokines (Handbook of Immunopharmacology)</i></a>. Boston: Academic Press. <a href="/wiki/Me%C4%91unarodni_standardni_broj_knjige" title="Međunarodni standardni broj knjige">ISBN</a> <a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A8%D1%82%D0%B0%D0%BC%D0%BF%D0%B0%D0%BD%D0%B8_%D0%B8%D0%B7%D0%B2%D0%BE%D1%80%D0%B8/0-12-498340-5" title="Посебно:Штампани извори/0-12-498340-5">0-12-498340-5</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.btitle=Cytokines+%28Handbook+of+Immunopharmacology%29&rft.date=1998&rft.genre=book&rft.isbn=0-12-498340-5&rft.place=Boston&rft.pub=Academic+Press&rft_id=http%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbook%2F9780124983403&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-KubyImmunology6th-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-KubyImmunology6th_3-0">^</a></b></span> <span class="reference-text"><cite class="citation book">Thomas J. Kindt; Richard A. Goldsby; Barbara Anne Osborne; Janis Kuby (2006). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/nlmcatalog/101275636"><i>Kuby Immunology</i></a> (6 изд.). New York: W H Freeman and company. <a href="/wiki/Me%C4%91unarodni_standardni_broj_knjige" title="Međunarodni standardni broj knjige">ISBN</a> <a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A8%D1%82%D0%B0%D0%BC%D0%BF%D0%B0%D0%BD%D0%B8_%D0%B8%D0%B7%D0%B2%D0%BE%D1%80%D0%B8/1429202114" title="Посебно:Штампани извори/1429202114">1429202114</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.au=Barbara+Anne+Osborne&rft.au=Janis+Kuby&rft.au=Richard+A.+Goldsby&rft.au=Thomas+J.+Kindt&rft.btitle=Kuby+Immunology&rft.date=2006&rft.edition=6&rft.genre=book&rft.isbn=1429202114&rft.place=New+York&rft.pub=W+H+Freeman+and+company&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fnlmcatalog%2F101275636&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><cite class="citation journal">van der Poll T, Keogh CV, Guirao X, Buurman WA, Kopf M, Lowry SF (1997). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_journal-of-infectious-diseases_1997-08_176_2/page/439">„Interleukin-6 gene-deficient mice show impaired defense against pneumococcal pneumonia”</a>. <i>J Infect Dis</i>. <b>176</b> (2): 439—44. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/9237710">9237710</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6+gene-deficient+mice+show+impaired+defense+against+pneumococcal+pneumonia&rft.au=Buurman%2C+WA&rft.au=Guirao%2C+X&rft.au=Keogh%2C+CV&rft.au=Kopf%2C+M&rft.au=Lowry%2C+SF&rft.aufirst=T&rft.aulast=van+der+Poll&rft.date=1997&rft.genre=article&rft.issue=2&rft.jtitle=J+Infect+Dis&rft.pages=439-44&rft.volume=176&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_journal-of-infectious-diseases_1997-08_176_2%2Fpage%2F439&rft_id=info%3Apmid%2F9237710&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-5">^</a></b></span> <span class="reference-text"><cite class="citation journal">Febbraio MA, Pedersen BK (2005). „Contraction-induced myokine production and release: is skeletal muscle an endocrine organ?”. <i>Exerc Sport Sci Rev</i>. <b>33</b> (3): 114—9. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16006818">16006818</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2F00003677-200507000-00003">10.1097/00003677-200507000-00003</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Contraction-induced+myokine+production+and+release%3A+is+skeletal+muscle+an+endocrine+organ%3F&rft.au=Pedersen%2C+BK&rft.aufirst=MA&rft.aulast=Febbraio&rft.date=2005&rft.genre=article&rft.issue=3&rft.jtitle=Exerc+Sport+Sci+Rev&rft.pages=114-9&rft.volume=33&rft_id=info%3Adoi%2F10.1097%2F00003677-200507000-00003&rft_id=info%3Apmid%2F16006818&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><cite class="citation journal">Benedict, C (2009). „Enhancing influence of intranasal IL-6 on slow-wave activity and memory consolidation during sleep”. <i>Federation of American Societies for Experimental Biology</i>. <b>23</b>: 3629—3636. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/19546306">19546306</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1096%2Ffj.08-122853">10.1096/fj.08-122853</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Enhancing+influence+of+intranasal+IL-6+on+slow-wave+activity+and+memory+consolidation+during+sleep&rft.aufirst=C&rft.aulast=Benedict&rft.date=2009&rft.genre=article&rft.jtitle=Federation+of+American+Societies+for+Experimental+Biology&rft.pages=3629-3636&rft.volume=23&rft_id=info%3Adoi%2F10.1096%2Ffj.08-122853&rft_id=info%3Apmid%2F19546306&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-7">^</a></b></span> <span class="reference-text"><cite class="citation journal">Heinrich PC, Behrmann, I, Müller-Newen G, Schaper F, Graeve L (1998). „Interleukin-6 type cytokine signalling through the gp130(Jak/STAT pathway”. <i>Biochem. J</i>. <b>334</b>: 297—314. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/9716487">9716487</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6+type+cytokine+signalling+through+the+gp130%28Jak%2FSTAT+pathway&rft.au=Heinrich+PC%2C+Behrmann%2C+I%2C+M%C3%BCller-Newen+G%2C+Schaper+F%2C+Graeve+L&rft.date=1998&rft.genre=article&rft.jtitle=Biochem.+J.&rft.pages=297-314&rft.volume=334&rft_id=info%3Apmid%2F9716487&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33; margin-left:0.3em">CS1 одржавање: Вишеструка имена: списак аутора (<a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%98%D0%B0:CS1_%D0%BE%D0%B4%D1%80%D0%B6%D0%B0%D0%B2%D0%B0%D1%9A%D0%B5:_%D0%92%D0%B8%D1%88%D0%B5%D1%81%D1%82%D1%80%D1%83%D0%BA%D0%B0_%D0%B8%D0%BC%D0%B5%D0%BD%D0%B0:_%D1%81%D0%BF%D0%B8%D1%81%D0%B0%D0%BA_%D0%B0%D1%83%D1%82%D0%BE%D1%80%D0%B0" title="Категорија:CS1 одржавање: Вишеструка имена: списак аутора">веза</a>)</span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text"><cite class="citation journal">Kishimoto T, Akira S, Narazaki M, Taga T (1995). „Interleukin-6 family of cytokines and gp130”. <i>Blood</i>. <b>86</b>: 1243—1254.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6+family+of+cytokines+and+gp130&rft.au=Akira%2C+S&rft.au=Narazaki%2C+M&rft.au=Taga%2C+T&rft.aufirst=T&rft.aulast=Kishimoto&rft.date=1995&rft.genre=article&rft.jtitle=Blood&rft.pages=1243-1254&rft.volume=86&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text"><cite class="citation journal">Heinrich PC, Behrmann I, Haan, S, Hermanns, HM, Müller-Newen G, Schaper, F (2003). „Principles of interleukin-6-type cytokine signalling and its regulation”. <i>Biochem. J</i>. <b>374</b>: 1—20. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/12773095">12773095</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1042%2FBJ20030407">10.1042/BJ20030407</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Principles+of+interleukin-6-type+cytokine+signalling+and+its+regulation&rft.au=Heinrich+PC%2C+Behrmann+I%2C+Haan%2C+S%2C+Hermanns%2C+HM%2C+M%C3%BCller-Newen+G%2C+Schaper%2C+F&rft.date=2003&rft.genre=article&rft.jtitle=Biochem.+J.&rft.pages=1-20&rft.volume=374&rft_id=info%3Adoi%2F10.1042%2FBJ20030407&rft_id=info%3Apmid%2F12773095&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33; margin-left:0.3em">CS1 одржавање: Вишеструка имена: списак аутора (<a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%98%D0%B0:CS1_%D0%BE%D0%B4%D1%80%D0%B6%D0%B0%D0%B2%D0%B0%D1%9A%D0%B5:_%D0%92%D0%B8%D1%88%D0%B5%D1%81%D1%82%D1%80%D1%83%D0%BA%D0%B0_%D0%B8%D0%BC%D0%B5%D0%BD%D0%B0:_%D1%81%D0%BF%D0%B8%D1%81%D0%B0%D0%BA_%D0%B0%D1%83%D1%82%D0%BE%D1%80%D0%B0" title="Категорија:CS1 одржавање: Вишеструка имена: списак аутора">веза</a>)</span></span> </li> <li id="cite_note-pmid14557255-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid14557255_10-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Schwantner A, Dingley AJ, Ozbek S, Rose-John S, Grötzinger J (2004). „Direct determination of the interleukin-6 binding epitope of the interleukin-6 receptor by NMR spectroscopy”. <i>J. Biol. Chem</i>. <b>279</b> (1): 571—6. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/14557255">14557255</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M311019200">10.1074/jbc.M311019200</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Direct+determination+of+the+interleukin-6+binding+epitope+of+the+interleukin-6+receptor+by+NMR+spectroscopy&rft.au=Dingley%2C+AJ&rft.au=Gr%C3%B6tzinger%2C+J&rft.au=Ozbek%2C+S&rft.au=Rose-John%2C+S&rft.aufirst=A&rft.aulast=Schwantner&rft.date=2004&rft.genre=article&rft.issue=1&rft.jtitle=J.+Biol.+Chem.&rft.pages=571-6&rft.volume=279&rft_id=info%3Adoi%2F10.1074%2Fjbc.M311019200&rft_id=info%3Apmid%2F14557255&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid12643274-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid12643274_11-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Schuster B, Kovaleva M, Sun Y, Regenhard P, Matthews V, Grötzinger J, Rose-John S, Kallen KJ (2003). „Signaling of human ciliary neurotrophic factor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNF”. <i>J. Biol. Chem</i>. <b>278</b> (11): 9528—35. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/12643274">12643274</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Signaling+of+human+ciliary+neurotrophic+factor+%28CNTF%29+revisited.+The+interleukin-6+receptor+can+serve+as+an+alpha-receptor+for+CTNF&rft.au=Gr%C3%B6tzinger%2C+J&rft.au=Kallen%2C+KJ&rft.au=Kovaleva%2C+M&rft.au=Matthews%2C+V&rft.au=Regenhard%2C+P&rft.au=Rose-John%2C+S&rft.au=Sun%2C+Y&rft.aufirst=B&rft.aulast=Schuster&rft.date=2003&rft.genre=article&rft.issue=11&rft.jtitle=J.+Biol.+Chem.&rft.pages=9528-35&rft.volume=278&rft_id=info%3Apmid%2F12643274&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid2788034-12"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid2788034_12-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Taga T, Hibi M, Hirata Y, Yamasaki K, Yasukawa K, Matsuda T, Hirano T, Kishimoto T (1989). „Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130”. <i>Cell</i>. <b>58</b> (3): 573—81. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/2788034">2788034</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6+triggers+the+association+of+its+receptor+with+a+possible+signal+transducer%2C+gp130&rft.au=Hibi%2C+M&rft.au=Hirano%2C+T&rft.au=Hirata%2C+Y&rft.au=Kishimoto%2C+T&rft.au=Matsuda%2C+T&rft.au=Yamasaki%2C+K&rft.au=Yasukawa%2C+K&rft.aufirst=T&rft.aulast=Taga&rft.date=1989&rft.genre=article&rft.issue=3&rft.jtitle=Cell&rft.pages=573-81&rft.volume=58&rft_id=info%3Apmid%2F2788034&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid15989626-13"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid15989626_13-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Kallen KJ, zum Büschenfelde KH, Rose-John S (1997). „The therapeutic potential of interleukin-6 hyperagonists and antagonists”. <i>Expert Opin Investig Drugs</i>. <b>6</b> (3): 237—66. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15989626">15989626</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1517%2F13543784.6.3.237">10.1517/13543784.6.3.237</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=The+therapeutic+potential+of+interleukin-6+hyperagonists+and+antagonists&rft.au=Rose-John%2C+S&rft.au=zum+B%C3%BCschenfelde%2C+KH&rft.aufirst=KJ&rft.aulast=Kallen&rft.date=1997&rft.genre=article&rft.issue=3&rft.jtitle=Expert+Opin+Investig+Drugs&rft.pages=237-66&rft.volume=6&rft_id=info%3Adoi%2F10.1517%2F13543784.6.3.237&rft_id=info%3Apmid%2F15989626&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid16306329-14"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid16306329_14-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Kristiansen OP, Mandrup-Poulsen T (2005). „Interleukin-6 and diabetes: the good, the bad, or the indifferent?”. <i>Diabetes</i>. 54 Suppl 2: S114—24. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16306329">16306329</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6+and+diabetes%3A+the+good%2C+the+bad%2C+or+the+indifferent%3F&rft.au=Mandrup-Poulsen%2C+T&rft.aufirst=OP&rft.aulast=Kristiansen&rft.date=2005&rft.genre=article&rft.jtitle=Diabetes&rft.pages=S114-24&rft.volume=54+Suppl+2&rft_id=info%3Apmid%2F16306329&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid17684929-15"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid17684929_15-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Dubiński A, Zdrojewicz Z (2007). „[The role of interleukin-6 in development and progression of atherosclerosis]”. <i>Pol. Merkur. Lekarski</i> (на језику: Polish). <b>22</b> (130): 291—4. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17684929">17684929</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=%5BThe+role+of+interleukin-6+in+development+and+progression+of+atherosclerosis%5D&rft.au=Zdrojewicz%2C+Z&rft.aufirst=A&rft.aulast=Dubi%C5%84ski&rft.date=2007&rft.genre=article&rft.issue=130&rft.jtitle=Pol.+Merkur.+Lekarski&rft.pages=291-4&rft.volume=22&rft_id=info%3Apmid%2F17684929&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33; margin-left:0.3em">CS1 одржавање: Непрепознат језик (<a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%98%D0%B0:CS1_%D0%BE%D0%B4%D1%80%D0%B6%D0%B0%D0%B2%D0%B0%D1%9A%D0%B5:_%D0%9D%D0%B5%D0%BF%D1%80%D0%B5%D0%BF%D0%BE%D0%B7%D0%BD%D0%B0%D1%82_%D1%98%D0%B5%D0%B7%D0%B8%D0%BA" title="Категорија:CS1 одржавање: Непрепознат језик">веза</a>)</span></span> </li> <li id="cite_note-pmid15230289-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid15230289_16-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Tackey E, Lipsky PE, Illei GG (2004). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2014821">„Rationale for interleukin-6 blockade in systemic lupus erythematosus”</a>. <i>Lupus</i>. <b>13</b> (5): 339—43. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2014821">2014821</a> <span typeof="mw:File"><span title="Слободан приступ"><img alt="Слободан приступ" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15230289">15230289</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Rationale+for+interleukin-6+blockade+in+systemic+lupus+erythematosus&rft.au=Illei%2C+GG&rft.au=Lipsky%2C+PE&rft.aufirst=E&rft.aulast=Tackey&rft.date=2004&rft.genre=article&rft.issue=5&rft.jtitle=Lupus&rft.pages=339-43&rft.volume=13&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2014821&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2014821&rft_id=info%3Apmid%2F15230289&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid11312117-17"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid11312117_17-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Smith PC, Hobisch A, Lin DL, Culig Z, Keller ET (2001). „Interleukin-6 and prostate cancer progression”. <i>Cytokine Growth Factor Rev</i>. <b>12</b> (1): 33—40. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/11312117">11312117</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6+and+prostate+cancer+progression&rft.au=Culig%2C+Z&rft.au=Hobisch%2C+A&rft.au=Keller%2C+ET&rft.au=Lin%2C+DL&rft.aufirst=PC&rft.aulast=Smith&rft.date=2001&rft.genre=article&rft.issue=1&rft.jtitle=Cytokine+Growth+Factor+Rev.&rft.pages=33-40&rft.volume=12&rft_id=info%3Apmid%2F11312117&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid16582692-18"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid16582692_18-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Nishimoto, N. (2006). „Interleukin-6 in rheumatoid arthritis”. <i>Curr Opin Rheumatol</i>. <b>18</b> (3): 277—81. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16582692">16582692</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2F01.bor.0000218949.19860.d1">10.1097/01.bor.0000218949.19860.d1</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6+in+rheumatoid+arthritis&rft.aufirst=N.&rft.aulast=Nishimoto&rft.date=2006&rft.genre=article&rft.issue=3&rft.jtitle=Curr+Opin+Rheumatol&rft.pages=277-81&rft.volume=18&rft_id=info%3Adoi%2F10.1097%2F01.bor.0000218949.19860.d1&rft_id=info%3Apmid%2F16582692&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-urlMedscape.com_Log_In-19"><span class="mw-cite-backlink"><b><a href="#cite_ref-urlMedscape.com_Log_In_19-0">^</a></b></span> <span class="reference-text"><cite class="citation web"><a rel="nofollow" class="external text" href="http://www.medscape.com/viewarticle/537309">„Cancer Patients Typically Have Increased Interleukin-6 Levels”</a>. <i>American Society of Clinical Oncology 2006 Annual Meeting, Abstracts 8632 and 8633</i>. Medscape.com. 26. 6. 2006.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Cancer+Patients+Typically+Have+Increased+Interleukin-6+Levels&rft.date=2006-06-26&rft.genre=unknown&rft.jtitle=American+Society+of+Clinical+Oncology+2006+Annual+Meeting%2C+Abstracts+8632+and+8633&rft_id=http%3A%2F%2Fwww.medscape.com%2Fviewarticle%2F537309&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid16083340-20"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid16083340_20-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Barton, B. E. (2005). „Interleukin-6 and new strategies for the treatment of cancer, hyperproliferative diseases and paraneoplastic syndromes”. <i>Expert Opin. Ther. Targets</i>. <b>9</b> (4): 737—52. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16083340">16083340</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1517%2F14728222.9.4.737">10.1517/14728222.9.4.737</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6+and+new+strategies+for+the+treatment+of+cancer%2C+hyperproliferative+diseases+and+paraneoplastic+syndromes&rft.aufirst=B.+E.&rft.aulast=Barton&rft.date=2005&rft.genre=article&rft.issue=4&rft.jtitle=Expert+Opin.+Ther.+Targets&rft.pages=737-52&rft.volume=9&rft_id=info%3Adoi%2F10.1517%2F14728222.9.4.737&rft_id=info%3Apmid%2F16083340&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid16899109-21"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid16899109_21-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Smolen JS, Maini RN (2006). „Interleukin-6: a new therapeutic target”. <i>Arthritis Res. Ther</i>. 8 Suppl 2: S5. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16899109">16899109</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1186%2Far1969">10.1186/ar1969</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6%3A+a+new+therapeutic+target&rft.au=Maini%2C+RN&rft.aufirst=JS&rft.aulast=Smolen&rft.date=2006&rft.genre=article&rft.jtitle=Arthritis+Res.+Ther.&rft.pages=S5&rft.volume=8+Suppl+2&rft_id=info%3Adoi%2F10.1186%2Far1969&rft_id=info%3Apmid%2F16899109&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Литература"><span id=".D0.9B.D0.B8.D1.82.D0.B5.D1.80.D0.B0.D1.82.D1.83.D1.80.D0.B0"></span>Литература</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&veaction=edit&section=6" title="Уредите одељак „Литература”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&action=edit&section=6" title="Уреди извор одељка: Литература"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r28440192">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-count references-column-count-2" style="column-count: 2;"> <ul><li><cite class="citation journal">De Kloet ER, Oitzl MS, Schöbitz B (1994). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_psychoneuroendocrinology_1994_19_2/page/121">„Cytokines and the brain corticosteroid receptor balance: relevance to pathophysiology of neuroendocrine-immune communication”</a>. <i>Psychoneuroendocrinology</i>. <b>19</b> (2): 121—34. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/8190832">8190832</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2F0306-4530%2894%2990002-7">10.1016/0306-4530(94)90002-7</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Cytokines+and+the+brain+corticosteroid+receptor+balance%3A+relevance+to+pathophysiology+of+neuroendocrine-immune+communication&rft.au=Oitzl%2C+MS&rft.au=Sch%C3%B6bitz%2C+B&rft.aufirst=ER&rft.aulast=De+Kloet&rft.date=1994&rft.genre=article&rft.issue=2&rft.jtitle=Psychoneuroendocrinology&rft.pages=121-34&rft.volume=19&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_psychoneuroendocrinology_1994_19_2%2Fpage%2F121&rft_id=info%3Adoi%2F10.1016%2F0306-4530%2894%2990002-7&rft_id=info%3Apmid%2F8190832&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Morishita R, Aoki M, Yo Y, Ogihara T (2003). „Hepatocyte growth factor as cardiovascular hormone: role of HGF in the pathogenesis of cardiovascular disease”. <i>Endocr. J</i>. <b>49</b> (3): 273—84. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/12201209">12201209</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1507%2Fendocrj.49.273">10.1507/endocrj.49.273</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Hepatocyte+growth+factor+as+cardiovascular+hormone%3A+role+of+HGF+in+the+pathogenesis+of+cardiovascular+disease&rft.au=Aoki%2C+M&rft.au=Ogihara%2C+T&rft.au=Yo%2C+Y&rft.aufirst=R&rft.aulast=Morishita&rft.date=2003&rft.genre=article&rft.issue=3&rft.jtitle=Endocr.+J.&rft.pages=273-84&rft.volume=49&rft_id=info%3Adoi%2F10.1507%2Fendocrj.49.273&rft_id=info%3Apmid%2F12201209&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Ishihara K, Hirano T (2003). „IL-6 in autoimmune disease and chronic inflammatory proliferative disease”. <i>Cytokine Growth Factor Rev</i>. <b>13</b> (4-5): 357—68. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/12220549">12220549</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS1359-6101%2802%2900027-8">10.1016/S1359-6101(02)00027-8</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=IL-6+in+autoimmune+disease+and+chronic+inflammatory+proliferative+disease&rft.au=Hirano%2C+T&rft.aufirst=K&rft.aulast=Ishihara&rft.date=2003&rft.genre=article&rft.issue=4-5&rft.jtitle=Cytokine+Growth+Factor+Rev.&rft.pages=357-68&rft.volume=13&rft_id=info%3Adoi%2F10.1016%2FS1359-6101%2802%2900027-8&rft_id=info%3Apmid%2F12220549&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Culig Z, Bartsch G, Hobisch A (2003). „Interleukin-6 regulates androgen receptor activity and prostate cancer cell growth”. <i>Mol. Cell. Endocrinol</i>. <b>197</b> (1-2): 231—8. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/12431817">12431817</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0303-7207%2802%2900263-0">10.1016/S0303-7207(02)00263-0</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6+regulates+androgen+receptor+activity+and+prostate+cancer+cell+growth&rft.au=Bartsch%2C+G&rft.au=Hobisch%2C+A&rft.aufirst=Z&rft.aulast=Culig&rft.date=2003&rft.genre=article&rft.issue=1-2&rft.jtitle=Mol.+Cell.+Endocrinol.&rft.pages=231-8&rft.volume=197&rft_id=info%3Adoi%2F10.1016%2FS0303-7207%2802%2900263-0&rft_id=info%3Apmid%2F12431817&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Rattazzi, M.; Puato, M; Faggin, E (2004). „C-reactive protein and interleukin-6 in <b>vascular disease</b>: culprits or passive bystanders?”. <i>J. Hypertens</i>. <b>21</b> (10): 1787—803. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/14508181">14508181</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2F01.hjh.0000084735.53355.44">10.1097/01.hjh.0000084735.53355.44</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=C-reactive+protein+and+interleukin-6+in+vascular+disease%3A+culprits+or+passive+bystanders%3F&rft.au=Faggin%2C+E&rft.au=Puato%2C+M&rft.aufirst=M.&rft.aulast=Rattazzi&rft.date=2004&rft.genre=article&rft.issue=10&rft.jtitle=J.+Hypertens.&rft.pages=1787-803&rft.volume=21&rft_id=info%3Adoi%2F10.1097%2F01.hjh.0000084735.53355.44&rft_id=info%3Apmid%2F14508181&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Berger, F. G. (2005). „The interleukin-6 gene: a susceptibility factor that may contribute to racial and ethnic disparities in <b>breast cancer</b> mortality”. <i>Breast Cancer Res. Treat</i>. <b>88</b> (3): 281—5. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15609131">15609131</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs10549-004-0726-0">10.1007/s10549-004-0726-0</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=The+interleukin-6+gene%3A+a+susceptibility+factor+that+may+contribute+to+racial+and+ethnic+disparities+in+breast+cancer+mortality&rft.aufirst=F.+G.&rft.aulast=Berger&rft.date=2005&rft.genre=article&rft.issue=3&rft.jtitle=Breast+Cancer+Res.+Treat.&rft.pages=281-5&rft.volume=88&rft_id=info%3Adoi%2F10.1007%2Fs10549-004-0726-0&rft_id=info%3Apmid%2F15609131&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Stenvinkel, P.; Ketteler, M; Johnson, RJ (2005). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_kidney-international_2005-04_67_4/page/1216">„IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia--the good, the bad, and the ugly”</a>. <i>Kidney Int</i>. <b>67</b> (4): 1216—33. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15780075">15780075</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1523-1755.2005.00200.x">10.1111/j.1523-1755.2005.00200.x</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=IL-10%2C+IL-6%2C+and+TNF-alpha%3A+central+factors+in+the+altered+cytokine+network+of+uremia--the+good%2C+the+bad%2C+and+the+ugly&rft.au=Johnson%2C+RJ&rft.au=Ketteler%2C+M&rft.aufirst=P.&rft.aulast=Stenvinkel&rft.date=2005&rft.genre=article&rft.issue=4&rft.jtitle=Kidney+Int.&rft.pages=1216-33&rft.volume=67&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_kidney-international_2005-04_67_4%2Fpage%2F1216&rft_id=info%3Adoi%2F10.1111%2Fj.1523-1755.2005.00200.x&rft_id=info%3Apmid%2F15780075&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Vgontzas, A. N.; Bixler, EO; Lin, HM (2005). „IL-6 and its circadian secretion in humans”. <i>Neuroimmunomodulation</i>. <b>12</b> (3): 131—40. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15905620">15905620</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1159%2F000084844">10.1159/000084844</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=IL-6+and+its+circadian+secretion+in+humans&rft.au=Bixler%2C+EO&rft.au=Lin%2C+HM&rft.aufirst=A.+N.&rft.aulast=Vgontzas&rft.date=2005&rft.genre=article&rft.issue=3&rft.jtitle=Neuroimmunomodulation&rft.pages=131-40&rft.volume=12&rft_id=info%3Adoi%2F10.1159%2F000084844&rft_id=info%3Apmid%2F15905620&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Jones, S. A. (2005). „Directing transition from innate to acquired immunity: defining a role for IL-6”. <i>J. Immunol</i>. <b>175</b> (6): 3463—8. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16148087">16148087</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Directing+transition+from+innate+to+acquired+immunity%3A+defining+a+role+for+IL-6&rft.aufirst=S.+A.&rft.aulast=Jones&rft.date=2005&rft.genre=article&rft.issue=6&rft.jtitle=J.+Immunol.&rft.pages=3463-8&rft.volume=175&rft_id=info%3Apmid%2F16148087&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Copeland, K. F. (2006). „Modulation of HIV-1 transcription by cytokines and chemokines”. <i>Mini reviews in medicinal chemistry</i>. <b>5</b> (12): 1093—101. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16375755">16375755</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.2174%2F138955705774933383">10.2174/138955705774933383</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Modulation+of+HIV-1+transcription+by+cytokines+and+chemokines&rft.aufirst=K.+F.&rft.aulast=Copeland&rft.date=2006&rft.genre=article&rft.issue=12&rft.jtitle=Mini+reviews+in+medicinal+chemistry&rft.pages=1093-101&rft.volume=5&rft_id=info%3Adoi%2F10.2174%2F138955705774933383&rft_id=info%3Apmid%2F16375755&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Mastorakos G, Ilias I (2007). „Interleukin-6: a cytokine and/or a major modulator of the response to somatic stress”. <i>Ann. N. Y. Acad. Sci</i>. <b>1088</b>: 373—81. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17192581">17192581</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1196%2Fannals.1366.021">10.1196/annals.1366.021</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3A%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD+6&rft.atitle=Interleukin-6%3A+a+cytokine+and%2For+a+major+modulator+of+the+response+to+somatic+stress&rft.au=Ilias%2C+I&rft.aufirst=G&rft.aulast=Mastorakos&rft.date=2007&rft.genre=article&rft.jtitle=Ann.+N.+Y.+Acad.+Sci.&rft.pages=373-81&rft.volume=1088&rft_id=info%3Adoi%2F10.1196%2Fannals.1366.021&rft_id=info%3Apmid%2F17192581&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="Спољашње_везе"><span id=".D0.A1.D0.BF.D0.BE.D1.99.D0.B0.D1.88.D1.9A.D0.B5_.D0.B2.D0.B5.D0.B7.D0.B5"></span>Спољашње везе</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&veaction=edit&section=7" title="Уредите одељак „Спољашње везе”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_6&action=edit&section=7" title="Уреди извор одељка: Спољашње везе"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r25554621">.mw-parser-output .side-box{margin:4px 0;box-sizing:border-box;border:1px solid #aaa;font-size:88%;line-height:1.25em;background-color:#f9f9f9;display:flow-root}.mw-parser-output .side-box-abovebelow,.mw-parser-output .side-box-text{padding:0.25em 0.9em}.mw-parser-output .side-box-image{padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .side-box-imageright{padding:2px 0.9em 2px 0;text-align:center}@media(min-width:500px){.mw-parser-output .side-box-flex{display:flex;align-items:center}.mw-parser-output .side-box-text{flex:1}}@media(min-width:720px){.mw-parser-output .side-box{width:238px}.mw-parser-output .side-box-right{clear:right;float:right;margin-left:1em}.mw-parser-output .side-box-left{margin-right:1em}}</style><div class="side-box side-box-right plainlinks sistersitebox"><style data-mw-deduplicate="TemplateStyles:r25554968">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style> <div class="side-box-flex"> <div class="side-box-image"><span class="noviewer" typeof="mw:File"><span><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png" decoding="async" width="30" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/45px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/59px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></span></span></div> <div class="side-box-text plainlist"><span style="font-weight:bold; font-style: italic;"><a href="https://commons.wikimedia.org/wiki/Category:Interleukin-6" class="extiw" title="commons:Category:Interleukin-6">Интерлеукин 6</a></span> на <a href="https://commons.wikimedia.org/wiki/%D0%93%D0%BB%D0%B0%D0%B2%D0%BD%D0%B0_%D1%81%D1%82%D1%80%D0%B0%D0%BD%D0%B0" class="extiw" title="commons:Главна страна">Викимедијиној остави</a>.</div></div> </div> <ul><li><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?name=Interleukin-6">Interleukin-6</a> на <i>US National Library of Medicine Medical Subject Headings</i> (<a href="/wiki/MeSH" title="MeSH">MeSH</a>)</li> <li><a rel="nofollow" class="external text" href="http://www.cancerindex.org/geneweb/IL6.htm">IL-6 изражавање у различитим врстама рака</a></li></ul> <div style="clear:both;"></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r25469611">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol 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class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><div class="mod-gallery mod-gallery-default"><div class="main"><div><ul class="gallery mw-gallery-traditional nochecker bordered-images" style="line-height:130%;"> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PDB_1alu_EBI.jpg" class="mw-file-description" title="1alu: Људски интерлеукин-6"><img alt="1alu: Људски интерлеукин-6" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e9/PDB_1alu_EBI.jpg/180px-PDB_1alu_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e9/PDB_1alu_EBI.jpg/270px-PDB_1alu_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e9/PDB_1alu_EBI.jpg/360px-PDB_1alu_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1alu">1alu</a></span></b>: Људски интерлеукин-6</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PDB_1il6_EBI.jpg" class="mw-file-description" title="1il6: Људски интерлеукин-6, НМР, минимизована средња структура"><img alt="1il6: Људски интерлеукин-6, НМР, минимизована средња структура" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2e/PDB_1il6_EBI.jpg/180px-PDB_1il6_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2e/PDB_1il6_EBI.jpg/270px-PDB_1il6_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2e/PDB_1il6_EBI.jpg/360px-PDB_1il6_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1il6">1il6</a></span></b>: Људски интерлеукин-6, <a href="/wiki/%D0%9D%D0%9C%D0%A0" class="mw-redirect" title="НМР">НМР</a>, минимизована средња структура</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PDB_1p9m_EBI.jpg" class="mw-file-description" title="1p9m: Кристална структура хексамерног људског ИЛ-6/ИЛ-6 алфа рецептор/гп130 комплекс"><img alt="1p9m: Кристална структура хексамерног људског ИЛ-6/ИЛ-6 алфа рецептор/гп130 комплекс" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/PDB_1p9m_EBI.jpg/180px-PDB_1p9m_EBI.jpg" decoding="async" width="180" height="99" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f6/PDB_1p9m_EBI.jpg/270px-PDB_1p9m_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f6/PDB_1p9m_EBI.jpg/360px-PDB_1p9m_EBI.jpg 2x" data-file-width="670" data-file-height="370" /></a></span></div> <div class="gallerytext"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1p9m">1p9m</a></span></b>: Кристална структура хексамерног људског <a href="/wiki/%D0%98%D0%9B-6" class="mw-redirect" title="ИЛ-6">ИЛ-6</a>/ИЛ-6 алфа рецептор/<a href="/wiki/Gp130" class="mw-redirect" title="Gp130">гп130</a> комплекс</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PDB_2il6_EBI.jpg" class="mw-file-description" title="2il6: Људски интерлеукин-6, НМР, 32 структуре"><img alt="2il6: Људски интерлеукин-6, НМР, 32 структуре" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/82/PDB_2il6_EBI.jpg/180px-PDB_2il6_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/82/PDB_2il6_EBI.jpg/270px-PDB_2il6_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/82/PDB_2il6_EBI.jpg/360px-PDB_2il6_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/2il6">2il6</a></span></b>: Људски интерлеукин-6, <a href="/wiki/%D0%9D%D0%9C%D0%A0" class="mw-redirect" title="НМР">НМР</a>, 32 структуре</div> </li> </ul></div></div></div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r25469611"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r24365370"></div><div role="navigation" class="navbox" aria-labelledby="Интерлеукини" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r25469611"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r24365379"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-прикажи"><a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD%D0%B8" title="Шаблон:Интерлеукини"><abbr title="Погледајте шаблон" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">п</abbr></a></li><li class="nv-разговор"><a href="/w/index.php?title=%D0%A0%D0%B0%D0%B7%D0%B3%D0%BE%D0%B2%D0%BE%D1%80_%D0%BE_%D1%88%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD%D1%83:%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD%D0%B8&action=edit&redlink=1" class="new" title="Разговор о шаблону:Интерлеукини (страница не постоји)"><abbr title="Разговарајте о шаблону" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">р</abbr></a></li><li class="nv-уреди"><a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A3%D1%80%D0%B5%D0%B4%D0%B8_%D1%81%D1%82%D1%80%D0%B0%D0%BD%D0%B8%D1%86%D1%83/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD%D0%B8" title="Посебно:Уреди страницу/Шаблон:Интерлеукини"><abbr title="Уредите шаблон" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">у</abbr></a></li></ul></div><div id="Интерлеукини" style="font-size:114%;margin:0 4em"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD%D0%B8" title="Интерлеукини">Интерлеукини</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_1" title="Интерлеукин 1">ИЛ-1</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_2" title="Интерлеукин 2">ИЛ-2</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_3" title="Интерлеукин 3">ИЛ-3</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_4" title="Интерлеукин 4">ИЛ-4</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_5" title="Интерлеукин 5">ИЛ-5</a></li> <li><a class="mw-selflink selflink">ИЛ-6</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_7" title="Интерлеукин 7">ИЛ-7</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_8" title="Интерлеукин 8">ИЛ-8</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_9" title="Интерлеукин 9">ИЛ-9</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_10" title="Интерлеукин 10">ИЛ-10</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_11" title="Интерлеукин 11">ИЛ-11</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_12" title="Интерлеукин 12">ИЛ-12</a> <ul><li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_12%D0%91" title="Интерлеукин 12Б">Б</a></li></ul></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_13" title="Интерлеукин 13">ИЛ-13</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_14" title="Интерлеукин 14">ИЛ-14</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_15" title="Интерлеукин 15">ИЛ-15</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_16" title="Интерлеукин 16">ИЛ-16</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_17" title="Интерлеукин 17">ИЛ-17</a> <ul><li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_17A" title="Интерлеукин 17A">A</a></li></ul></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_18" title="Интерлеукин 18">ИЛ-18</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_19" title="Интерлеукин 19">ИЛ-19</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_20" title="Интерлеукин 20">ИЛ-20</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_21" title="Интерлеукин 21">ИЛ-21</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_22" title="Интерлеукин 22">ИЛ-22</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_23" title="Интерлеукин 23">ИЛ-23</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_24" title="Интерлеукин 24">ИЛ-24</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_25" title="Интерлеукин 25">ИЛ-25</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_26" title="Интерлеукин 26">ИЛ-26</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_27" title="Интерлеукин 27">ИЛ-27</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_28" title="Интерлеукин 28">ИЛ-28</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_29" title="Интерлеукин 29">ИЛ-29</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_30" title="Интерлеукин 30">ИЛ-30</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_31" title="Интерлеукин 31">ИЛ-31</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_32" title="Интерлеукин 32">ИЛ-32</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_33" title="Интерлеукин 33">ИЛ-33</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_34" title="Интерлеукин 34">ИЛ-34</a></li> <li><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_35" title="Интерлеукин 35">ИЛ-35</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r25469611"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r24365370"></div><div role="navigation" class="navbox" aria-labelledby="Ћелијска_комуникација:_Цитокини" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r25469611"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r24365379"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-прикажи"><a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:%D0%A6%D0%B8%D1%82%D0%BE%D0%BA%D0%B8%D0%BD%D0%B8" title="Шаблон:Цитокини"><abbr title="Погледајте шаблон" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">п</abbr></a></li><li class="nv-разговор"><a href="/wiki/%D0%A0%D0%B0%D0%B7%D0%B3%D0%BE%D0%B2%D0%BE%D1%80_%D0%BE_%D1%88%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD%D1%83:%D0%A6%D0%B8%D1%82%D0%BE%D0%BA%D0%B8%D0%BD%D0%B8" title="Разговор о шаблону:Цитокини"><abbr title="Разговарајте о шаблону" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">р</abbr></a></li><li class="nv-уреди"><a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A3%D1%80%D0%B5%D0%B4%D0%B8_%D1%81%D1%82%D1%80%D0%B0%D0%BD%D0%B8%D1%86%D1%83/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:%D0%A6%D0%B8%D1%82%D0%BE%D0%BA%D0%B8%D0%BD%D0%B8" title="Посебно:Уреди страницу/Шаблон:Цитокини"><abbr title="Уредите шаблон" style=";background:#e7dcc3;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">у</abbr></a></li></ul></div><div id="Ћелијска_комуникација:_Цитокини" style="font-size:114%;margin:0 4em"><a href="/wiki/%D0%8B%D0%B5%D0%BB%D0%B8%D1%98%D1%81%D0%BA%D0%B0_%D0%BA%D0%BE%D0%BC%D1%83%D0%BD%D0%B8%D0%BA%D0%B0%D1%86%D0%B8%D1%98%D0%B0" title="Ћелијска комуникација">Ћелијска комуникација</a>: <a href="/wiki/%D0%A6%D0%B8%D1%82%D0%BE%D0%BA%D0%B8%D0%BD%D0%B8" class="mw-redirect" title="Цитокини">Цитокини</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">По фамилији</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD" class="mw-redirect" title="Интерлеукин">Интерлеукин</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/%D0%98%D0%9B-1" class="mw-redirect" title="ИЛ-1">ИЛ-1</a> суперфамилија</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_1" title="Интерлеукин 1">1</a> (<a href="/wiki/Antagonist_interleukin-1_receptora" title="Antagonist interleukin-1 receptora">1Ra</a>) •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_18" title="Интерлеукин 18">18</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_33" title="Интерлеукин 33">33</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">попут <a href="/wiki/%D0%98%D0%9B-6" class="mw-redirect" title="ИЛ-6">ИЛ-6</a>/<a href="/wiki/Glikoprotein_130" title="Glikoprotein 130">гп130</a> користећи</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a class="mw-selflink selflink">6</a>  •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_11" title="Интерлеукин 11">11</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_27" title="Интерлеукин 27">27</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_30" title="Интерлеукин 30">30</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_31" title="Интерлеукин 31">31</a> (+ne IL <a href="/wiki/Onkostatin_M" title="Onkostatin M">Онкостатин М</a>, <a href="/wiki/Inhibitorni_faktor_leukemije" title="Inhibitorni faktor leukemije">Инхибиторни фактор леукемије</a>, <a href="/wiki/Cilijarni_neurotrofni_faktor" title="Cilijarni neurotrofni faktor">Цилијарни неуротрофни фактор</a>, <a href="/wiki/Kardiotrofin_1" title="Kardiotrofin 1">Кардиотрофин 1</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/%D0%98%D0%9B-10" class="mw-redirect" title="ИЛ-10">ИЛ-10</a> фамилија</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_10" title="Интерлеукин 10">10</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_19" title="Интерлеукин 19">19</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_20" title="Интерлеукин 20">20</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_22" title="Интерлеукин 22">22</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_24" title="Интерлеукин 24">24</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_26" title="Интерлеукин 26">26</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Interferon_tip_III" title="Interferon tip III">Интерферон тип III</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_28" title="Интерлеукин 28">28</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_29" title="Интерлеукин 29">29</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Zajedni%C4%8Dki_gama_lanac" title="Zajednički gama lanac">Заједнички γ-ланац</a> фамилија</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_2" title="Интерлеукин 2">2</a>/<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_15" title="Интерлеукин 15">15</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_3" title="Интерлеукин 3">3</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_4" title="Интерлеукин 4">4</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_7" title="Интерлеукин 7">7</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_9" title="Интерлеукин 9">9</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_13" title="Интерлеукин 13">13</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_21" title="Интерлеукин 21">21</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/%D0%98%D0%9B-12" class="mw-redirect" title="ИЛ-12">ИЛ-12</a> фамилија</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_12" title="Интерлеукин 12">12</a> (<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_12%D0%91" title="Интерлеукин 12Б">Б</a>) •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_23" title="Интерлеукин 23">23</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_27" title="Интерлеукин 27">27</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_35" title="Интерлеукин 35">35</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Drugi</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_5" title="Интерлеукин 5">5</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_8" title="Интерлеукин 8">8</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_14" title="Интерлеукин 14">14</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_16" title="Интерлеукин 16">16</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_17" title="Интерлеукин 17">17</a>/<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_25" title="Интерлеукин 25">25</a> (<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_17A" title="Интерлеукин 17A">A</a>) •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_32" title="Интерлеукин 32">32</a>  •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_34" title="Интерлеукин 34">34</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Hemokini" title="Hemokini">Хемокини</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">CCL</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CCL1" title="CCL1">1</a> •  <a href="/wiki/CCL2" title="CCL2">2</a> •  <a href="/wiki/Makrofagni_inflamatorni_protein" title="Makrofagni inflamatorni protein">3</a> •  <a href="/wiki/CCL4" title="CCL4">4</a> •  <a href="/wiki/CCL5" title="CCL5">5</a> •  <a href="/wiki/CCL6" title="CCL6">6</a> •  <a href="/wiki/CCL7" title="CCL7">7</a> •  <a href="/wiki/CCL8" title="CCL8">8</a> •  <a href="/wiki/CCL9" title="CCL9">9</a> •  <a href="/wiki/CCL9" title="CCL9">10</a> •  <a href="/wiki/CCL11" title="CCL11">11</a> •  <a href="/wiki/CCL12" title="CCL12">12</a> •  <a href="/wiki/CCL13" title="CCL13">13</a> •  <a href="/wiki/CCL14" title="CCL14">14</a> •  <a href="/wiki/CCL15" title="CCL15">15</a> •  <a href="/wiki/CCL16" title="CCL16">16</a> •  <a href="/wiki/CCL17" title="CCL17">17</a> •  <a href="/wiki/CCL18" title="CCL18">18</a> •  <a href="/wiki/CCL19" title="CCL19">19</a> •  <a href="/wiki/CCL20" title="CCL20">20</a> •  <a href="/wiki/CCL21" title="CCL21">21</a> •  <a href="/wiki/CCL22" title="CCL22">22</a> •  <a href="/wiki/CCL23" title="CCL23">23</a> •  <a href="/wiki/CCL24" title="CCL24">24</a> •  <a href="/wiki/CCL25" title="CCL25">25</a> •  <a href="/wiki/CCL26" title="CCL26">26</a> •  <a href="/wiki/CCL27" title="CCL27">27</a> •  <a href="/wiki/CCL28" title="CCL28">28</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">CXCL</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CXCL1" title="CXCL1">1</a> •  <a href="/wiki/CXCL2" title="CXCL2">2</a> •  <a href="/wiki/CXCL3" title="CXCL3">3</a> •  <a href="/wiki/Trombocit_faktor_4" title="Trombocit faktor 4">4</a> •  <a href="/wiki/CXCL5" title="CXCL5">5</a> •  <a href="/wiki/CXCL6" title="CXCL6">6</a> •  <a href="/wiki/CXCL7" title="CXCL7">7</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_8" title="Интерлеукин 8">8</a> •  <a href="/wiki/CXCL9" title="CXCL9">9</a> •  <a href="/wiki/CXCL10" title="CXCL10">10</a> •  <a href="/wiki/CXCL11" title="CXCL11">11</a> •  <a href="/wiki/CXCL12" title="CXCL12">12</a> •  <a href="/wiki/CXCL13" title="CXCL13">13</a> •  <a href="/wiki/CXCL14" title="CXCL14">14</a> •  <a href="/wiki/CXCL15" title="CXCL15">15</a> •  <a href="/wiki/CXCL16" title="CXCL16">16</a> •  <a href="/wiki/CXCL17" title="CXCL17">17</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">CX3CL</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CX3CL1" title="CX3CL1">1</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">XCL</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/XCL1" title="XCL1">1</a> •  <a href="/wiki/XCL2" title="XCL2">2</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Faktori_nekroze_tumora" title="Faktori nekroze tumora">ТНФ</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Главни</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">ТНФ-алфа</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">ТНФ (<a href="/wiki/Ligand_(biohemija)" title="Ligand (biohemija)">лиганд</a>) суперфамилија</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/4-1BB_ligand" title="4-1BB ligand">4-1ББ лиганд</a> •  <a href="/wiki/Faktor_aktivacije_B-%C4%87elija" title="Faktor aktivacije B-ćelija">Фактор активације Б-ћелијa</a> •  <a href="/wiki/Fas_ligand" title="Fas ligand">ФАС лиганд</a> •  <a href="/wiki/Limfotoksin" title="Limfotoksin">Лимфотоксин</a> •  <a href="/wiki/OX40L" title="OX40L">OX40L</a> •  <a href="/wiki/RANKL" title="RANKL">RANKL</a> •  <a href="/wiki/TRAIL" title="TRAIL">TRAIL</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Klaster_diferencijacije" title="Klaster diferencijacije">Кластер диференцијације</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/CD70" title="CD70">CD70</a> •  <a href="/wiki/CD153" title="CD153">CD153</a> •  <a href="/wiki/CD154" title="CD154">CD154</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Interferon" title="Interferon">Интерферон</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Interferon_tip_I" title="Interferon tip I">I</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em">alfa (<a href="/wiki/Pegilirani_interferon_alfa-2a" title="Pegilirani interferon alfa-2a">Пегилирани 2а</a>, <a href="/wiki/Pegilirani_interferon_alfa-2b" title="Pegilirani interferon alfa-2b">Пегилирани 2б</a>), бета (<a href="/wiki/Interferon_beta-1a" title="Interferon beta-1a">1a</a>, <a href="/wiki/Interferon_beta-1b" title="Interferon beta-1b">1б</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Interferon_tip_II" title="Interferon tip II">II</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Interferon-gama" title="Interferon-gama">Гама</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite"><a href="/wiki/Interferon_tip_III" title="Interferon tip III">III</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_28" title="Интерлеукин 28">ИЛ -28</a> •  <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_29" title="Интерлеукин 29">ИЛ-29</a></div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">Други</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Monokin" title="Monokin">Монокин</a> •  <a href="/wiki/Limfokin" title="Limfokin">Лимфокин</a> (<a href="/wiki/Limfotoksin" title="Limfotoksin">Лимфотоксин</a>, <a href="/wiki/Faktor_transfera" title="Faktor transfera">Фактор трансфера</a>) •  <a href="/wiki/Faktor_rasta" title="Faktor rasta">Фактор раста</a> •  <a href="/wiki/Hematopoeza" title="Hematopoeza">Хематопоеза</a> (<a href="/wiki/Faktor_stem_%C4%87elija" title="Faktor stem ćelija">Фактор стем ћелија</a>, <a href="/wiki/Faktor_stimulacije_kolonije" title="Faktor stimulacije kolonije">Фактор стимулaције колоније</a>) •  <a href="/wiki/GPI_(gen)" title="GPI (gen)">Фактор аутокриног мотилитета</a> •  <a href="/wiki/Osteopontin" title="Osteopontin">Остеопонтин</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">По функцији</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><i><a href="/wiki/Proinflamatorni_citokin" title="Proinflamatorni citokin">проинфламаторни цитокин</a></i> (<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_1" title="Интерлеукин 1">ИЛ-1</a>, <a href="/wiki/Faktor_nekroze_tumora-alfa" title="Faktor nekroze tumora-alfa">ТНФ-алфа</a>) •  <a href="/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije"><i>T<sub>х</sub>1</i></a> (<a href="/wiki/Interferon-gama" title="Interferon-gama">ИНФ-гама</a> и <a href="/wiki/Faktor_nekroze_tumora-beta" class="mw-redirect" title="Faktor nekroze tumora-beta">ТНФ-бета</a>) •  <a href="/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije"><i>T<sub>х</sub>2</i></a> (<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_4" title="Интерлеукин 4">ИЛ-4</a>, <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_5" title="Интерлеукин 5">ИЛ-5</a>, <a class="mw-selflink selflink">ИЛ-6</a>, <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_10" title="Интерлеукин 10">ИЛ-10</a>, <a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_13" title="Интерлеукин 13">ИЛ-13</a>) •  <a href="/wiki/T_pomo%C4%87ne_17_%C4%87elije" title="T pomoćne 17 ćelije"><i>T<sub>х</sub>17</i></a> (<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_17" title="Интерлеукин 17">ИЛ-17</a>,<a href="/wiki/%D0%98%D0%BD%D1%82%D0%B5%D1%80%D0%BB%D0%B5%D1%83%D0%BA%D0%B8%D0%BD_22" title="Интерлеукин 22">ИЛ-22</a>)</div></td></tr></tbody></table></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1&useformat=desktop" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div 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