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delivery system.</title> <meta name="description" content="Search results for: prodrug delivery system."> <meta name="keywords" content="prodrug delivery system."> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="prodrug delivery system."> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 18921</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: prodrug delivery system.</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18921</span> An Activatable Prodrug for the Treatment of Metastatic Tumors</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eun-Joong%20Kim">Eun-Joong Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Sankarprasad%20Bhuniya"> Sankarprasad Bhuniya</a>, <a href="https://publications.waset.org/abstracts/search?q=Hyunseung%20Lee"> Hyunseung Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Hyun%20Min%20Kim"> Hyun Min Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Chaejoon%20Cheong"> Chaejoon Cheong</a>, <a href="https://publications.waset.org/abstracts/search?q=Su-khendu%20Maiti"> Su-khendu Maiti</a>, <a href="https://publications.waset.org/abstracts/search?q=Kwan%20Soo%20Hong"> Kwan Soo Hong</a>, <a href="https://publications.waset.org/abstracts/search?q=Jong%20Seung%20Kim"> Jong Seung Kim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Metastatic cancers have historically been difficult to treat. However, metastatic tumors have been found to have high levels of reactive oxygen species such as hydrogen peroxide (H2O2), supporting the hypothesis that a prodrug could be activated by intracellular H2O2 and lead to a potential anti-metastatic therapy. In this study, prodrug 7 was designed to be activated by H2O2-mediated boronate oxidation, resulting in activation of the fluorophore for detection and release of the therapeutic agent, SN-38. Drug release from prodrug 7 was investigated by monitoring fluorescence after addition of H2O2 to the cancer cells. Prodrug 7 activated by H2O2 selectively inhibited tumor cell growth. Furthermore, intratracheally administered prodrug 7 showed effective anti-tumor activity in a mouse model of metastatic lung disease. Thus, this H2O2-responsive prodrug has therapeutic potential as a novel treatment for metastatic cancer via cellular imaging with fluorescence as well as selective release of the anti-cancer drug, SN-38. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hydrogen%20peroxide" title="hydrogen peroxide">hydrogen peroxide</a>, <a href="https://publications.waset.org/abstracts/search?q=prodrug" title=" prodrug"> prodrug</a>, <a href="https://publications.waset.org/abstracts/search?q=metastatic%20tumors" title=" metastatic tumors"> metastatic tumors</a>, <a href="https://publications.waset.org/abstracts/search?q=fluorescence" title=" fluorescence"> fluorescence</a> </p> <a href="https://publications.waset.org/abstracts/16855/an-activatable-prodrug-for-the-treatment-of-metastatic-tumors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16855.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">453</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18920</span> Upconversion Nanoparticle-Mediated Carbon Monoxide Prodrug Delivery System for Cancer Therapy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yaw%20Opoku-Damoah">Yaw Opoku-Damoah</a>, <a href="https://publications.waset.org/abstracts/search?q=Run%20Zhang"> Run Zhang</a>, <a href="https://publications.waset.org/abstracts/search?q=Hang%20Thu%20Ta"> Hang Thu Ta</a>, <a href="https://publications.waset.org/abstracts/search?q=Zhi%20Ping%20Xu"> Zhi Ping Xu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Gas therapy is still at an early stage of research and development. Even though most gasotransmitters have proven their therapeutic potential, their handling, delivery, and controlled release have been extremely challenging. This research work employs a versatile nanosystem that is capable of delivering a gasotransmitter in the form of a photo-responsive carbon monoxide-releasing molecule (CORM) for targeted cancer therapy. The therapeutic action was mediated by upconversion nanoparticles (UCNPs) designed to transfer bio-friendly low energy near-infrared (NIR) light to ultraviolet (UV) light capable of triggering carbon monoxide (CO) from a water-soluble amphiphilic manganese carbonyl complex CORM incorporated into a carefully designed lipid drug delivery system. Herein, gaseous CO that plays a role as a gasotransmitter with cytotoxic and homeostatic properties was investigated to instigate cellular apoptosis. After successfully synthesizing the drug delivery system, the ability of the system to encapsulate and mediate the sustained release of CO after light excitation was demonstrated. CO fluorescence probe (COFP) was successfully employed to determine the in vitro drug release profile upon NIR light irradiation. The uptake of nanoparticles enhanced by folates and its receptor interaction was also studied for cellular uptake purposes. The anticancer potential of the final lipid nanoparticle Lipid/UCNPs/CORM/FA (LUCF) was also determined by cell viability assay. Intracellular CO release and a subsequent therapeutic action involving ROS production, mitochondrial damage, and CO production was also evaluated. In all, this current project aims to use in vitro studies to determine the potency and efficiency of a NIR-mediated CORM prodrug delivery system. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carbon%20monoxide-releasing%20molecule" title="carbon monoxide-releasing molecule">carbon monoxide-releasing molecule</a>, <a href="https://publications.waset.org/abstracts/search?q=upconversion%20nanoparticles" title=" upconversion nanoparticles"> upconversion nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=site-specific%20delivery" title=" site-specific delivery"> site-specific delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=amphiphilic%20manganese%20carbonyl%20complex" title=" amphiphilic manganese carbonyl complex"> amphiphilic manganese carbonyl complex</a>, <a href="https://publications.waset.org/abstracts/search?q=prodrug%20delivery%20system." title=" prodrug delivery system. "> prodrug delivery system. </a> </p> <a href="https://publications.waset.org/abstracts/124308/upconversion-nanoparticle-mediated-carbon-monoxide-prodrug-delivery-system-for-cancer-therapy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/124308.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">112</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18919</span> An Activatable Theranostic for Targeted Cancer Therapy and Imaging</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sankarprasad%20Bhuniya">Sankarprasad Bhuniya</a>, <a href="https://publications.waset.org/abstracts/search?q=Sukhendu%20Maiti"> Sukhendu Maiti</a>, <a href="https://publications.waset.org/abstracts/search?q=Eun-Joong%20Kim"> Eun-Joong Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Hyunseung%20Lee"> Hyunseung Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Jonathan%20L.%20Sessler"> Jonathan L. Sessler</a>, <a href="https://publications.waset.org/abstracts/search?q=Kwan%20Soo%20Hong"> Kwan Soo Hong</a>, <a href="https://publications.waset.org/abstracts/search?q=Jong%20Seung%20Kim"> Jong Seung Kim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A new theranostic strategy is described. It is based on the use of an “all in one” prodrug, namely the biotinylated piperazine-rhodol conjugate 4a. This conjugate, which incorporates the anticancer drug SN-38, undergoes self-immolative cleavage when exposed to biological thiols. This leads to the tumor-targeted release of the active SN-38 payload along with fluorophore 1a. This release is made selective as the result of the biotin functionality. Fluorophore 1a is 32-fold more fluorescent than prodrug 4a. It permits the delivery and release of the SN-38 payload to be monitored easily in vitro and in vivo, as inferred from cell studies and ex vivo analyses of mice xenografts derived HeLa cells, respectively. Prodrug 4a also displays anticancer activity in the HeLa cell murine xenograft tumor model. On the basis of these findings we suggest that the present strategy, which combines within a single agent the key functions of targeting, release, imaging, and treatment, may have a role to play in cancer diagnosis and therapy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=theranostic" title="theranostic">theranostic</a>, <a href="https://publications.waset.org/abstracts/search?q=prodrug" title=" prodrug"> prodrug</a>, <a href="https://publications.waset.org/abstracts/search?q=cancer%20therapy" title=" cancer therapy"> cancer therapy</a>, <a href="https://publications.waset.org/abstracts/search?q=fluorescence" title=" fluorescence"> fluorescence</a> </p> <a href="https://publications.waset.org/abstracts/16859/an-activatable-theranostic-for-targeted-cancer-therapy-and-imaging" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16859.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">537</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18918</span> Effect of Building Construction Sizes on Project Delivery Methods in Nigeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nuruddeen%20Usman">Nuruddeen Usman</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Sani"> Mohammad Sani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The performance of project delivery methods has been an issue of concern to various stakeholders in the construction industry. The contracting system of project delivery is the traditional system used in the delivery of most public projects in Nigeria. The direct labor system is used most times as an alternative to the traditional system. There were so many complain about the performance of contracting system and the suitability of direct labor as an alternative to the delivery of public projects. Therefore, this paper is aimed at investigating the effect of project size on the project delivery methods in the completed public buildings. Questionnaires were self-administered to managerial staff in the study area and analyzed using descriptive statistics. The findings reveals that contracting system was choosing for large size building construction project delivery with higher frequency (F) of 40 (76.9%) against direct labor with 12 (23.1%). While the small size project, the result revealed a frequency (F) of 26 (50%) for contracting system and direct labor system respectively. Base on the research findings, the contracting system, was recommended for all sizes of building construction project delivery while direct labor system can only use as an alternative for small size building construction projects delivery. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=construction%20size" title="construction size">construction size</a>, <a href="https://publications.waset.org/abstracts/search?q=contracting%20system" title=" contracting system"> contracting system</a>, <a href="https://publications.waset.org/abstracts/search?q=direct%20labour" title=" direct labour"> direct labour</a>, <a href="https://publications.waset.org/abstracts/search?q=effect" title=" effect"> effect</a> </p> <a href="https://publications.waset.org/abstracts/34754/effect-of-building-construction-sizes-on-project-delivery-methods-in-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34754.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">457</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18917</span> Structuring and Visualizing Healthcare Claims Data Using Systems Architecture Methodology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Inas%20S.%20Khayal">Inas S. Khayal</a>, <a href="https://publications.waset.org/abstracts/search?q=Weiping%20Zhou"> Weiping Zhou</a>, <a href="https://publications.waset.org/abstracts/search?q=Jonathan%20Skinner"> Jonathan Skinner</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Healthcare delivery systems around the world are in crisis. The need to improve health outcomes while decreasing healthcare costs have led to an imminent call to action to transform the healthcare delivery system. While Bioinformatics and Biomedical Engineering have primarily focused on biological level data and biomedical technology, there is clear evidence of the importance of the delivery of care on patient outcomes. Classic singular decomposition approaches from reductionist science are not capable of explaining complex systems. Approaches and methods from systems science and systems engineering are utilized to structure healthcare delivery system data. Specifically, systems architecture is used to develop a multi-scale and multi-dimensional characterization of the healthcare delivery system, defined here as the Healthcare Delivery System Knowledge Base. This paper is the first to contribute a new method of structuring and visualizing a multi-dimensional and multi-scale healthcare delivery system using systems architecture in order to better understand healthcare delivery. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=health%20informatics" title="health informatics">health informatics</a>, <a href="https://publications.waset.org/abstracts/search?q=systems%20thinking" title=" systems thinking"> systems thinking</a>, <a href="https://publications.waset.org/abstracts/search?q=systems%20architecture" title=" systems architecture"> systems architecture</a>, <a href="https://publications.waset.org/abstracts/search?q=healthcare%20delivery%20system" title=" healthcare delivery system"> healthcare delivery system</a>, <a href="https://publications.waset.org/abstracts/search?q=data%20analytics" title=" data analytics"> data analytics</a> </p> <a href="https://publications.waset.org/abstracts/69032/structuring-and-visualizing-healthcare-claims-data-using-systems-architecture-methodology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/69032.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">348</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18916</span> Recent Trends in Supply Chain Delivery Models</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alfred%20L.%20Guiffrida">Alfred L. Guiffrida </a> </p> <p class="card-text"><strong>Abstract:</strong></p> A review of the literature on supply chain delivery models which use delivery windows to measure delivery performance is presented. The review herein serves to meet the following objectives: (i) provide a synthesis of previously published literature on supply chain delivery performance models, (ii) provide in one paper a consolidation of research that can serve as a single source to keep researchers up to date with the research developments in supply chain delivery models, and (iii) identify gaps in the modeling of supply chain delivery performance which could stimulate new research agendas. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=delivery%20performance" title="delivery performance">delivery performance</a>, <a href="https://publications.waset.org/abstracts/search?q=delivery%20window" title=" delivery window"> delivery window</a>, <a href="https://publications.waset.org/abstracts/search?q=supply%20chain%20delivery%20models" title=" supply chain delivery models"> supply chain delivery models</a>, <a href="https://publications.waset.org/abstracts/search?q=supply%20chain%20performance" title=" supply chain performance"> supply chain performance</a> </p> <a href="https://publications.waset.org/abstracts/6540/recent-trends-in-supply-chain-delivery-models" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/6540.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">422</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18915</span> Sustainability Assessment of Food Delivery with Last-Mile Delivery Droids, A Case Study at the European Commission's JRC Ispra Site</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ada%20Garus">Ada Garus</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper presents the outcomes of the sustainability assessment of food delivery with a last-mile delivery service introduced in a real-world case study. The methodology used in the sustainability assessment integrates multi-criteria decision-making analysis, sustainability pillars, and scenario analysis to best reflect the conflicting needs of stakeholders involved in the last mile delivery system. The case study provides an application of the framework to the food delivery system of the Joint Research Centre of the European Commission where three alternative solutions were analyzed I) the existent state in which individuals frequent the local cantine or pick up their food, using their preferred mode of transport II) the hypothetical scenario in which individuals can only order their food using the delivery droid system III) a scenario in which the food delivery droid based system is introduced as a supplement to the current system. The environmental indices are calculated using a simulation study in which decision regarding the food delivery is predicted using a multinomial logit model. The vehicle dynamics model is used to predict the fuel consumption of the regular combustion engines vehicles used by the cantine goers and the electricity consumption of the droid. The sustainability assessment allows for the evaluation of the economic, environmental, and social aspects of food delivery, making it an apt input for policymakers. Moreover, the assessment is one of the first studies to investigate automated delivery droids, which could become a frequent addition to the urban landscape in the near future. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=innovations%20in%20transportation%20technologies" title="innovations in transportation technologies">innovations in transportation technologies</a>, <a href="https://publications.waset.org/abstracts/search?q=behavioural%20change%20and%20mobility" title=" behavioural change and mobility"> behavioural change and mobility</a>, <a href="https://publications.waset.org/abstracts/search?q=urban%20freight%20logistics" title=" urban freight logistics"> urban freight logistics</a>, <a href="https://publications.waset.org/abstracts/search?q=innovative%20transportation%20systems" title=" innovative transportation systems"> innovative transportation systems</a> </p> <a href="https://publications.waset.org/abstracts/142926/sustainability-assessment-of-food-delivery-with-last-mile-delivery-droids-a-case-study-at-the-european-commissions-jrc-ispra-site" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/142926.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">193</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18914</span> Development of an Erodable Matrix Drug Delivery Platform for Controled Delivery of Non Steroidal Anti Inflamatory Drugs Using Melt Granulation Process</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Hilsana">A. Hilsana</a>, <a href="https://publications.waset.org/abstracts/search?q=Vinay%20U.%20Rao"> Vinay U. Rao</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Sudhakar"> M. Sudhakar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Even though a number of non-steroidal anti-inflammatory drugs (NSAIDS) are available with different chemistries, they share a common solubility characteristic that is they are relatively more soluble in alkaline environment and practically insoluble in acidic environment. This work deals with developing a wax matrix drug delivery platform for controlled delivery of three model NSAIDS, Diclofenac sodium (DNa), Mefenamic acid (MA) and Naproxen (NPX) using the melt granulation technique. The aim of developing the platform was to have a general understanding on how an erodible matrix system modulates drug delivery rate and extent and how it can be optimized to give a delivery system which shall release the drug as per a common target product profile (TPP). Commonly used waxes like Cetostearyl alcohol and stearic acid were used singly an in combination to achieve a TPP of not 15 to 35% in 1 hour and not less than 80% Q in 24 hours. Full factorial design of experiments was followed for optimization of the formulation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=NSAIDs" title="NSAIDs">NSAIDs</a>, <a href="https://publications.waset.org/abstracts/search?q=controlled%20delivery" title=" controlled delivery"> controlled delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=target%20product%20profile" title=" target product profile"> target product profile</a>, <a href="https://publications.waset.org/abstracts/search?q=melt%20granulation" title=" melt granulation"> melt granulation</a> </p> <a href="https://publications.waset.org/abstracts/9021/development-of-an-erodable-matrix-drug-delivery-platform-for-controled-delivery-of-non-steroidal-anti-inflamatory-drugs-using-melt-granulation-process" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9021.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">334</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18913</span> A Mathematical Model for a Two-Stage Assembly Flow-Shop Scheduling Problem with Batch Delivery System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Saeedeh%20Ahmadi%20Basir">Saeedeh Ahmadi Basir</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Mahdavi%20Mazdeh"> Mohammad Mahdavi Mazdeh</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Namakshenas"> Mohammad Namakshenas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Manufacturers often dispatch jobs in batches to reduce delivery costs. However, sending several jobs in batches can have a negative effect on other scheduling-related objective functions such as minimizing the number of tardy jobs which is often used to rate managers’ performance in many manufacturing environments. This paper aims to minimize the number of weighted tardy jobs and the sum of delivery costs of a two-stage assembly flow-shop problem in a batch delivery system. We present a mixed-integer linear programming (MILP) model to solve the problem. As this is an MILP model, the commercial solver (the CPLEX solver) is not guaranteed to find the optimal solution for large-size problems at a reasonable amount of time. We present several numerical examples to confirm the accuracy of the model. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=scheduling" title="scheduling">scheduling</a>, <a href="https://publications.waset.org/abstracts/search?q=two-stage%20assembly%20flow-shop" title=" two-stage assembly flow-shop"> two-stage assembly flow-shop</a>, <a href="https://publications.waset.org/abstracts/search?q=tardy%20jobs" title=" tardy jobs"> tardy jobs</a>, <a href="https://publications.waset.org/abstracts/search?q=batched%20delivery%20system" title=" batched delivery system"> batched delivery system</a> </p> <a href="https://publications.waset.org/abstracts/61194/a-mathematical-model-for-a-two-stage-assembly-flow-shop-scheduling-problem-with-batch-delivery-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61194.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">460</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18912</span> Polysaccharide-Based Oral Delivery Systems for Site Specific Delivery in Gastro-Intestinal Tract</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kaarunya%20Sampathkumar">Kaarunya Sampathkumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Say%20Chye%20Joachim%20Loo"> Say Chye Joachim Loo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Oral delivery is regarded as the facile method for the administration of active pharmaceutical ingredients (API) and drug carriers. In an initiative towards sustainable nanotechnology, an oral nano-delivery system has been developed that is made entirely of food-based materials and can also act as a site-specific delivery device depending on the stimulus encountered in different parts of the gastrointestinal tract (GIT). The delivery system has been fabricated from food grade polysaccharide materials like chitosan and starch through electrospraying technique without the use of any organic solvents. A nutraceutical extracted from an Indian medicinal plant, has been loaded into the nano carrier to test its efficacy in encapsulation and stimuli based release of the active ingredient. The release kinetics of the nutraceutical from the carrier was evaluated in simulated gastric, intestinal and colonic fluid and was found to be triggered both by the enzymes and the pH in each part of the intestinal tract depending on the polysaccharide being used. The toxicity of the nanoparticles on the intestinal epithelial cells was tested and found to be relatively safe for up to 24 hours at a concentration of 0.2 mg/mL with cellular uptake also being observed. The developed nano carrier thus serves as a promising delivery vehicle for targeted delivery to different parts of the GIT with the inherent conditions of the GIT itself acting as the stimulus. In addition, being fabricated from food grade materials, the carrier could be potentially used for the targeted delivery of nutrients through functional foods. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bioavailability" title="bioavailability">bioavailability</a>, <a href="https://publications.waset.org/abstracts/search?q=chitosan" title=" chitosan"> chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=delivery%20systems" title=" delivery systems"> delivery systems</a>, <a href="https://publications.waset.org/abstracts/search?q=encapsulation" title=" encapsulation"> encapsulation</a> </p> <a href="https://publications.waset.org/abstracts/90354/polysaccharide-based-oral-delivery-systems-for-site-specific-delivery-in-gastro-intestinal-tract" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/90354.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">213</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18911</span> The Effect of Backing Layer on Adhesion Properties of Single Layer Ketoprofen Transdermal Drug Delivery System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Hamedanlou">Maryam Hamedanlou</a>, <a href="https://publications.waset.org/abstracts/search?q=Shahla%20Hajializadeh"> Shahla Hajializadeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The transdermal drug delivery system is one of the types of novel drug delivery system that the drug is absorbed into the skin. The major considerations for designing and producing transdermal patch are small size, suitable drug release and good adhering. In this study, drug-in-adhesive transdermal patch contained non-steroidal anti-inflammatory ketoprofen is prepared. Also, the effect of non-woven fabric and plastic backing layers on adhesion properties is assessed. The results of the test, demonstrated the use of plastic backing layer increases tack and peel rather than non-woven fabric type. The balance tack with plastic backing layer patch is 6.7 (N/mm2), and the fabric one is 3.8 (N/mm2), and their peel is 9.2 (N/25mm) and 8.3 (N/25mm) by arrangement. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=transdermal%20drug%20delivery%20system" title="transdermal drug delivery system">transdermal drug delivery system</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20layer%20patch%20of%20ketoprofen" title=" single layer patch of ketoprofen"> single layer patch of ketoprofen</a>, <a href="https://publications.waset.org/abstracts/search?q=plastic%20layer" title=" plastic layer"> plastic layer</a>, <a href="https://publications.waset.org/abstracts/search?q=fabric%20backing%20layer" title=" fabric backing layer"> fabric backing layer</a> </p> <a href="https://publications.waset.org/abstracts/55471/the-effect-of-backing-layer-on-adhesion-properties-of-single-layer-ketoprofen-transdermal-drug-delivery-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/55471.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">252</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18910</span> Survival Analysis Based Delivery Time Estimates for Display FAB</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Paul%20Han">Paul Han</a>, <a href="https://publications.waset.org/abstracts/search?q=Jun-Geol%20Baek"> Jun-Geol Baek</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the flat panel display industry, the scheduler and dispatching system to meet production target quantities and the deadline of production are the major production management system which controls each facility production order and distribution of WIP (Work in Process). In dispatching system, delivery time is a key factor for the time when a lot can be supplied to the facility. In this paper, we use survival analysis methods to identify main factors and a forecasting model of delivery time. Of survival analysis techniques to select important explanatory variables, the cox proportional hazard model is used to. To make a prediction model, the Accelerated Failure Time (AFT) model was used. Performance comparisons were conducted with two other models, which are the technical statistics model based on transfer history and the linear regression model using same explanatory variables with AFT model. As a result, the Mean Square Error (MSE) criteria, the AFT model decreased by 33.8% compared to the existing prediction model, decreased by 5.3% compared to the linear regression model. This survival analysis approach is applicable to implementing a delivery time estimator in display manufacturing. And it can contribute to improve the productivity and reliability of production management system. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=delivery%20time" title="delivery time">delivery time</a>, <a href="https://publications.waset.org/abstracts/search?q=survival%20analysis" title=" survival analysis"> survival analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=Cox%20PH%20model" title=" Cox PH model"> Cox PH model</a>, <a href="https://publications.waset.org/abstracts/search?q=accelerated%20failure%20time%20model" title=" accelerated failure time model"> accelerated failure time model</a> </p> <a href="https://publications.waset.org/abstracts/4881/survival-analysis-based-delivery-time-estimates-for-display-fab" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/4881.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">543</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18909</span> Status Report of the Express Delivery Industry in China</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ying%20Bo%20Xie">Ying Bo Xie</a>, <a href="https://publications.waset.org/abstracts/search?q=Hisa%20Yuki%20Kurokawa"> Hisa Yuki Kurokawa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Due to the fast development, China's express delivery industry has involved in a dilemma that the service quality are keeping decreasing while the construction rate of delivery network cannot meet the customers’ demand. In order to get out of this dilemma and enjoy a succession development rate, it is necessary to understand the current situation of China's express delivery industry. Firstly, the evolution of China's express delivery industry was systematical presented. Secondly, according to the number of companies and the amount of parcels they has dealt each year, the merits and faults of tow kind of operating pattern was analyzed. Finally, based on the characteristics of these express companies, the problems of China's express delivery industry was divided into several types and the countermeasures were given out respectively. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=China" title="China">China</a>, <a href="https://publications.waset.org/abstracts/search?q=express%20delivery%20industry" title=" express delivery industry"> express delivery industry</a>, <a href="https://publications.waset.org/abstracts/search?q=status" title=" status"> status</a>, <a href="https://publications.waset.org/abstracts/search?q=problem" title=" problem"> problem</a> </p> <a href="https://publications.waset.org/abstracts/31014/status-report-of-the-express-delivery-industry-in-china" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31014.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">363</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18908</span> Development and Evaluation of Simvastatin Based Self Nanoemulsifying Drug Delivery System (SNEDDS) for Treatment of Alzheimer's Disease</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hardeep">Hardeep</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this research work to improve the solubility and bioavailability of Simvastatin using a self nanoemulsifying drug delivery system (SNEDDS). Self emulsifying property of various oils including essential oils was evaluated with suitable surfactants and co-surfactants. Validation of a method for accuracy, repeatability, Interday and intraday precision, ruggedness, and robustness were within acceptable limits. The liquid SNEDDS was prepared and optimized using a ternary phase diagram, thermodynamic, centrifugation and cloud point studies. The globule size of optimized formulations was less than 200 nm which could be an acceptable nanoemulsion size range. The mean droplet size, drug loading, PDI and zeta potential were found to be 141.0 nm, 92.22%, 0.23 and -10.13 mV and 153.5nm, 93.89 % ,0.41 and -11.7 mV and 164.26 nm, 95.26% , 0.41 and -10.66mV respectively. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=simvastatin" title="simvastatin">simvastatin</a>, <a href="https://publications.waset.org/abstracts/search?q=self%20nanoemulsifying%20drug%20delivery%20system" title=" self nanoemulsifying drug delivery system"> self nanoemulsifying drug delivery system</a>, <a href="https://publications.waset.org/abstracts/search?q=solubility" title=" solubility"> solubility</a>, <a href="https://publications.waset.org/abstracts/search?q=bioavailability" title=" bioavailability"> bioavailability</a> </p> <a href="https://publications.waset.org/abstracts/138999/development-and-evaluation-of-simvastatin-based-self-nanoemulsifying-drug-delivery-system-snedds-for-treatment-of-alzheimers-disease" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/138999.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">201</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18907</span> Analysis of the Omnichannel Delivery Network with Application to Last Mile Delivery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Colette%20Malyack">Colette Malyack</a>, <a href="https://publications.waset.org/abstracts/search?q=Pius%20Egbelu"> Pius Egbelu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Business-to-Customer (B2C) delivery options have improved to meet increased demand in recent years. The change in end users has forced logistics networks to focus on customer service and sentiment that would have previously been the priority of the company or organization of origin. This has led to increased pressure on logistics companies to extend traditional B2B networks into a B2C solution while accommodating additional costs, roadblocks, and customer sentiment; the result has been the creation of the omnichannel delivery network encompassing a number of traditional and modern methods of package delivery. In this paper the many solutions within the omnichannel delivery network are defined and discussed. It can be seen through this analysis that the omnichannel delivery network can be applied to reduce the complexity of package delivery and provide customers with more options. Applied correctly the result is a reduction in cost to the logistics company over time, even with an initial increase in cost to obtain the technology. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=network%20planning" title="network planning">network planning</a>, <a href="https://publications.waset.org/abstracts/search?q=last%20mile%20delivery" title=" last mile delivery"> last mile delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=omnichannel%20delivery%20network" title=" omnichannel delivery network"> omnichannel delivery network</a>, <a href="https://publications.waset.org/abstracts/search?q=omnichannel%20logistics" title=" omnichannel logistics"> omnichannel logistics</a> </p> <a href="https://publications.waset.org/abstracts/134544/analysis-of-the-omnichannel-delivery-network-with-application-to-last-mile-delivery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/134544.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">150</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18906</span> Feasibility of Using Bike Lanes in Conjunctions with Sidewalks for Ground Drone Applications in Last Mile Delivery for Dense Urban Areas</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20Bazyar%20Shourabi">N. Bazyar Shourabi</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Nyarko"> K. Nyarko</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Scott"> C. Scott</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Jeihnai"> M. Jeihnai</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ground drones have the potential to reduce the cost and time of making last-mile deliveries. They also have the potential to make a huge impact on human life. Despite this potential, little work has gone into developing a suitable feasibility model for ground drone delivery in dense urban areas. Today, most of the experimental ground delivery drones utilize sidewalks only, with just a few of them starting to use bike lanes, which a significant portion of some urban areas have. This study works on the feasibility of using bike lanes in conjunction with sidewalks for ground drone applications in last-mile delivery for dense urban areas. This work begins with surveying bike lanes and sidewalks within the city of Boston using Geographic Information System (GIS) software to determine the percentage of coverage currently available within the city. Then six scenarios are examined. Based on this research, a mathematical model is developed. The daily cost of delivering packages using each scenario is calculated by the mathematical model. Comparing the drone delivery scenarios with the traditional method of package delivery using trucks will provide essential information concerning the feasibility of implementing routing protocols that combine the use of sidewalks and bike lanes. The preliminary results of the model show that ground drones that can travel via sidewalks or bike lanes have the potential to significantly reduce delivery cost. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ground%20drone" title="ground drone">ground drone</a>, <a href="https://publications.waset.org/abstracts/search?q=intelligent%20transportation%20system" title=" intelligent transportation system"> intelligent transportation system</a>, <a href="https://publications.waset.org/abstracts/search?q=last-mile%20delivery" title=" last-mile delivery"> last-mile delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=sidewalk%20robot" title=" sidewalk robot"> sidewalk robot</a> </p> <a href="https://publications.waset.org/abstracts/116913/feasibility-of-using-bike-lanes-in-conjunctions-with-sidewalks-for-ground-drone-applications-in-last-mile-delivery-for-dense-urban-areas" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/116913.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">144</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18905</span> Importance of Infrastucture Delivery and Management in South Africa</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Onyeka%20Nkwonta">Onyeka Nkwonta</a>, <a href="https://publications.waset.org/abstracts/search?q=Theo%20Haupt"> Theo Haupt</a>, <a href="https://publications.waset.org/abstracts/search?q=Karana%20Padayachee"> Karana Padayachee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study aims primarily to identify potential causes of the bottlenecks in the public sector that affect delivery and formulate evidence-based interventions to improve delivery and management of infrastructure projects. An initial literature review was carried out on infrastructural development and delivery in South Africa, with the aim to formulate evidence-based interventions to improve delivery within the sector. The infrastructure delivery management model was developed to map out best practice delivery processes. These will become the backbone on which improvement initiatives that will be developed within participating stakeholders. The model will, in turn, support a range of methodologies, including the risk system and a knowledge management framework. It will also look at key challenges facing departments with the ability to ensure knowledge and skills transfer at various sectors. The research is limited because the findings were based on existing literature. This study adopted an indirect approach for infrastructure management by focussing on the challenges faced and approaches adopted to overcome these challenges. This may narrow the consideration of some of the viewpoints, thereby limiting the richness of experience available to this research. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=infrastructure" title="infrastructure">infrastructure</a>, <a href="https://publications.waset.org/abstracts/search?q=management" title=" management"> management</a>, <a href="https://publications.waset.org/abstracts/search?q=challenges" title=" challenges"> challenges</a>, <a href="https://publications.waset.org/abstracts/search?q=South%20Africa" title=" South Africa"> South Africa</a> </p> <a href="https://publications.waset.org/abstracts/138074/importance-of-infrastucture-delivery-and-management-in-south-africa" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/138074.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">138</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18904</span> Synthesis and Characterisation of Starch-PVP as Encapsulation Material for Drug Delivery System </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nungki%20Rositaningsih">Nungki Rositaningsih</a>, <a href="https://publications.waset.org/abstracts/search?q=Emil%20Budianto"> Emil Budianto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Starch has been widely used as an encapsulation material for drug delivery system. However, starch hydrogel is very easily degraded during metabolism in human stomach. Modification of this material is needed to improve the encapsulation process in drug delivery system, especially for gastrointestinal drug. In this research, three modified starch-based hydrogels are synthesized i.e. Crosslinked starch hydrogel, Semi- and Full- Interpenetrating Polymer Network (IPN) starch hydrogel using Poly(N-Vinyl-Pyrrolidone). Non-modified starch hydrogel was also synthesized as a control. All of those samples were compared as biomaterials, floating drug delivery, and their ability in loading drug test. Biomaterial characterizations were swelling test, stereomicroscopy observation, Differential Scanning Calorimetry (DSC), and Fourier Transform Infrared Spectroscopy (FTIR). Buoyancy test and stereomicroscopy scanning were done for floating drug delivery characterizations. Lastly, amoxicillin was used as test drug, and characterized with UV-Vis spectroscopy for loading drug observation. Preliminary observation showed that Full-IPN has the most dense and elastic texture, followed by Semi-IPN, Crosslinked, and Non-modified in the last position. Semi-IPN and Crosslinked starch hydrogel have the most ideal properties and will not be degraded easily during metabolism. Therefore, both hydrogels could be considered as promising candidates for encapsulation material. Further analysis and issues will be discussed in the paper. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomaterial" title="biomaterial">biomaterial</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20delivery%20system" title=" drug delivery system"> drug delivery system</a>, <a href="https://publications.waset.org/abstracts/search?q=interpenetrating%20polymer%20network" title=" interpenetrating polymer network"> interpenetrating polymer network</a>, <a href="https://publications.waset.org/abstracts/search?q=poly%28N-vinyl-pyrrolidone%29" title=" poly(N-vinyl-pyrrolidone)"> poly(N-vinyl-pyrrolidone)</a>, <a href="https://publications.waset.org/abstracts/search?q=starch%20hydrogel" title=" starch hydrogel"> starch hydrogel</a> </p> <a href="https://publications.waset.org/abstracts/56315/synthesis-and-characterisation-of-starch-pvp-as-encapsulation-material-for-drug-delivery-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56315.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">251</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18903</span> Release Management with Continuous Delivery: A Case Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Maruf%20Aytekin">A. Maruf Aytekin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We present our approach on using continuous delivery pattern for release management. One of the key practices of agile and lean teams is the continuous delivery of new features to stakeholders. The main benefits of this approach lie in the ability to release new applications rapidly which has real strategic impact on the competitive advantage of an organization. Organizations that successfully implement Continuous Delivery have the ability to evolve rapidly to support innovation, provide stable and reliable software in more efficient ways, decrease the amount of resources need for maintenance, and lower the software delivery time and costs. One of the objectives of this paper is to elaborate a case study where IT division of Central Securities Depository Institution (MKK) of Turkey apply Continuous Delivery pattern to improve release management process. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=automation" title="automation">automation</a>, <a href="https://publications.waset.org/abstracts/search?q=continuous%20delivery" title=" continuous delivery"> continuous delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=deployment" title=" deployment"> deployment</a>, <a href="https://publications.waset.org/abstracts/search?q=release%20management" title=" release management"> release management</a> </p> <a href="https://publications.waset.org/abstracts/10343/release-management-with-continuous-delivery-a-case-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/10343.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">256</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18902</span> A Case Study of Assessing the Impact of Electronic Payment System on the Service Delivery of Banks in Nigeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Idris%20Lawal">Idris Lawal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Electronic payment system is simply a payment or monetary transaction made over the internet or a network of computers. This study was carried out in order to assess how electronic payment system has impacted on banks service delivery, to examine the efficiency of electronic payment system in Nigeria and to determine the level of customer's satisfaction as a direct result of the deployment of electronic payment systems. It is an empirical study conducted using structured questionnaire distributed to officials and customers of Access Bank plc. Chi-square(x2) was adopted for the purpose of data analysis. The result of the study showed that the development of electronic payment system offer great benefit to bank customers including improved services, reduced turn-around time, ease of banking transaction, significant cost saving etc. The study recommends that customer protection laws should be properly put in place to safeguard the interest of end users of e-payment instruments. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bank" title="bank">bank</a>, <a href="https://publications.waset.org/abstracts/search?q=electronic%20payment%20systems" title=" electronic payment systems"> electronic payment systems</a>, <a href="https://publications.waset.org/abstracts/search?q=service%20delivery" title=" service delivery"> service delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=customer%27s%20satisfaction" title=" customer's satisfaction"> customer's satisfaction</a> </p> <a href="https://publications.waset.org/abstracts/16423/a-case-study-of-assessing-the-impact-of-electronic-payment-system-on-the-service-delivery-of-banks-in-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16423.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">399</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18901</span> A Multi-Agent System for Accelerating the Delivery Process of Clinical Diagnostic Laboratory Results Using GSM Technology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ayman%20M.%20Mansour">Ayman M. Mansour</a>, <a href="https://publications.waset.org/abstracts/search?q=Bilal%20Hawashin"> Bilal Hawashin</a>, <a href="https://publications.waset.org/abstracts/search?q=Hesham%20Alsalem"> Hesham Alsalem</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Faster delivery of laboratory test results is one of the most noticeable signs of good laboratory service and is often used as a key performance indicator of laboratory performance. Despite the availability of technology, the delivery time of clinical laboratory test results continues to be a cause of customer dissatisfaction which makes patients feel frustrated and they became careless to get their laboratory test results. The Medical Clinical Laboratory test results are highly sensitive and could harm patients especially with the severe case if they deliver in wrong time. Such results affect the treatment done by physicians if arrived at correct time efforts should, therefore, be made to ensure faster delivery of lab test results by utilizing new trusted, Robust and fast system. In this paper, we proposed a distributed Multi-Agent System to enhance and faster the process of laboratory test results delivery using SMS. The developed system relies on SMS messages because of the wide availability of GSM network comparing to the other network. The software provides the capability of knowledge sharing between different units and different laboratory medical centers. The system was built using java programming. To implement the proposed system we had many possible techniques. One of these is to use the peer-to-peer (P2P) model, where all the peers are treated equally and the service is distributed among all the peers of the network. However, for the pure P2P model, it is difficult to maintain the coherence of the network, discover new peers and ensure security. Also, security is a quite important issue since each node is allowed to join the network without any control mechanism. We thus take the hybrid P2P model, a model between the Client/Server model and the pure P2P model using GSM technology through SMS messages. This model satisfies our need. A GUI has been developed to provide the laboratory staff with the simple and easy way to interact with the system. This system provides quick response rate and the decision is faster than the manual methods. This will save patients life. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=multi-agent%20system" title="multi-agent system">multi-agent system</a>, <a href="https://publications.waset.org/abstracts/search?q=delivery%20process" title=" delivery process"> delivery process</a>, <a href="https://publications.waset.org/abstracts/search?q=GSM%20technology" title=" GSM technology"> GSM technology</a>, <a href="https://publications.waset.org/abstracts/search?q=clinical%20laboratory%20results" title=" clinical laboratory results"> clinical laboratory results</a> </p> <a href="https://publications.waset.org/abstracts/56346/a-multi-agent-system-for-accelerating-the-delivery-process-of-clinical-diagnostic-laboratory-results-using-gsm-technology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/56346.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">249</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18900</span> Assessing the Impact of Electronic Payment Systems on the Service Delivery of Banks: Case of Nigeria </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Idris%20lawal">Idris lawal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The most recent development in the Nigerian payment system is the venture into “electronic payment system”. Electronic payment system is simply a payment or monetary transaction made over the internet or a network of computers. This study was carried out in order to assess how electronic payment system has impacted on banks service delivery, to examine the efficiency of electronic payment system in Nigeria and to determine the level of customer’s satisfaction as a direct result of the deployment of electronic payment systems. The study was conducted using structured questionnaire distributed to 50 bank officials and customers of Access Bank plc. Chi-square(x2) was adopted for the purpose of data analysis. The result of the study showed that the development of electronic payment system offer great benefit to bank customers including; improved services, reduced turn-around time, ease of banking transaction, significant cost saving etc. The study recommend that customer protection laws should be properly put in place to safeguard the interest of end users of e-payment instruments, the banking industry and government should show strong commitment and effort to educate the populace on the benefit of patronizing e-payment system to facilitate economic development. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=electronic%20payment%20system" title="electronic payment system">electronic payment system</a>, <a href="https://publications.waset.org/abstracts/search?q=service%20delivery" title=" service delivery"> service delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=bank" title=" bank"> bank</a>, <a href="https://publications.waset.org/abstracts/search?q=Nigeria" title=" Nigeria"> Nigeria</a> </p> <a href="https://publications.waset.org/abstracts/13394/assessing-the-impact-of-electronic-payment-systems-on-the-service-delivery-of-banks-case-of-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13394.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">281</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18899</span> Iontophoretic Drug Transport of Some Anti-Diabetic Agents</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ashish%20Jain">Ashish Jain</a>, <a href="https://publications.waset.org/abstracts/search?q=Satish%20Nayak"> Satish Nayak</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Transdermal iontophoretic drug delivery system is viable drug delivery platform technology and has a strong market worldwide. Transdermal drug delivery system is particularly desirable for therapeutic agents that need prolonged administration at controlled plasma level. This makes appropriateness to antihypertensive and anti-diabetic agents for their transdermal development. Controlled zero order absorption, easily termination of drug delivery and easy to administration also support for popularity of transdermal delivery. In this current research iontophoretic delivery of various anti diabetic agents like glipizide, glibenclamide and glimepiride were carried out. The experiments were carried out at different drug concentrations and different current densities using cathodal iontophoresis. Diffusion cell for iontophoretic permeation study was modified according to Glikfield Design. Pig skin was used for in vitro permeation study and for the in-vivo study New Zealand rabbits were used. At all concentration level iontophoresis showed enhanced permeation rate compared to passive controls. Iontophoretic transports of selected drugs were found to be increased with the current densities. Results showed that target permeation rate for selected drugs could be achieved with the aid of iontophoresis by increasing the area in an appreciable range. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=transdermal" title="transdermal">transdermal</a>, <a href="https://publications.waset.org/abstracts/search?q=iontophoresis" title=" iontophoresis"> iontophoresis</a>, <a href="https://publications.waset.org/abstracts/search?q=pig%20skin" title=" pig skin"> pig skin</a>, <a href="https://publications.waset.org/abstracts/search?q=rabbits" title=" rabbits"> rabbits</a>, <a href="https://publications.waset.org/abstracts/search?q=glipizide" title=" glipizide"> glipizide</a>, <a href="https://publications.waset.org/abstracts/search?q=glibeclamide" title=" glibeclamide"> glibeclamide</a> </p> <a href="https://publications.waset.org/abstracts/45635/iontophoretic-drug-transport-of-some-anti-diabetic-agents" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45635.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">384</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18898</span> A Relational Case-Based Reasoning Framework for Project Delivery System Selection</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yang%20Cui">Yang Cui</a>, <a href="https://publications.waset.org/abstracts/search?q=Yong%20Qiang%20Chen"> Yong Qiang Chen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> An appropriate project delivery system (PDS) is crucial to the success of a construction project. Case-based reasoning (CBR) is a useful support for PDS selection. However, the traditional CBR approach represents cases as attribute-value vectors without taking relations among attributes into consideration, and could not calculate the similarity when the structures of cases are not strictly same. Therefore, this paper solves this problem by adopting the relational case-based reasoning (RCBR) approach for PDS selection, considering both the structural similarity and feature similarity. To develop the feature terms of the construction projects, the criteria and factors governing PDS selection process are first identified. Then, feature terms for the construction projects are developed. Finally, the mechanism of similarity calculation and a case study indicate how RCBR works for PDS selection. The adoption of RCBR in PDS selection expands the scope of application of traditional CBR method and improves the accuracy of the PDS selection system. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=relational%20cased-based%20reasoning" title="relational cased-based reasoning">relational cased-based reasoning</a>, <a href="https://publications.waset.org/abstracts/search?q=case-based%20reasoning" title=" case-based reasoning"> case-based reasoning</a>, <a href="https://publications.waset.org/abstracts/search?q=project%20delivery%20system" title=" project delivery system"> project delivery system</a>, <a href="https://publications.waset.org/abstracts/search?q=PDS%20selection" title=" PDS selection"> PDS selection</a> </p> <a href="https://publications.waset.org/abstracts/9087/a-relational-case-based-reasoning-framework-for-project-delivery-system-selection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9087.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">432</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18897</span> Development of Nanoparticulate Based Chimeric Drug Delivery System Using Drug Bioconjugated Plant Virus Capsid on Biocompatible Nanoparticles</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Indu%20Barwal">Indu Barwal</a>, <a href="https://publications.waset.org/abstracts/search?q=Shloka%20Thakur"> Shloka Thakur</a>, <a href="https://publications.waset.org/abstracts/search?q=Subhash%20C.%20Yadav"> Subhash C. Yadav</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The plant virus capsid protein based nanoparticles are extensively studied for their application in biomedical research for development of nanomedicines and drug delivery systems. We have developed a chimeric drug delivery system by controlled in vitro assembly of separately bioconjugated fluorescent dye (as reporting molecule), folic acid (as receptor binding biomolecule for targeted delivery) and doxorubicin (as anticancer drug) using modified EDC NHS chemistry on heterologously overexpressed (E. coli) capsid proteins of cowpea chlorotic mottle virus (CCMV). This chimeric vehicle was further encapsidated on gold nanoparticles (20nm) coated with 5≠ thiolated DNA probe to neutralize the positive charge of capsid proteins. This facilitates the in vitro assembly of modified capsid subunits on the gold nanoparticles to develop chimeric GNPs encapsidated targeted drug delivery system. The bioconjugation of functionalities, number of functionality on capsid subunits as well as virus like nanoparticles, structural stability and in vitro assembly were confirmed by SDS PAGE, relative absorbance, MALDI TOF, ESI-MS, Circular dichroism, intrinsic tryptophan fluorescence, zeta particle size analyzer and TEM imaging. This vehicle was stable at pH 4.0 to 8.0 suitable for many organelles targeting. This in vitro assembled chimeric plant virus like particles could be suitable for ideal drug delivery vehicles for subcutaneous cancer treatment and could be further modified for other type of cancer treatment by conjugating other functionalities (targeting, drug) on capsids. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chimeric%20drug%20delivery%20vehicles" title="chimeric drug delivery vehicles">chimeric drug delivery vehicles</a>, <a href="https://publications.waset.org/abstracts/search?q=bioconjugated%20plant" title=" bioconjugated plant"> bioconjugated plant</a>, <a href="https://publications.waset.org/abstracts/search?q=virus" title=" virus"> virus</a>, <a href="https://publications.waset.org/abstracts/search?q=capsid" title=" capsid"> capsid</a> </p> <a href="https://publications.waset.org/abstracts/18298/development-of-nanoparticulate-based-chimeric-drug-delivery-system-using-drug-bioconjugated-plant-virus-capsid-on-biocompatible-nanoparticles" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18298.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">493</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18896</span> A Study on the Computation of Gourava Indices for Poly-L Lysine Dendrimer and Its Biomedical Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Helen">M. Helen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chemical graph serves as a convenient model for any real or abstract chemical system. Dendrimers are novel three dimensional hyper branched globular nanopolymeric architectures. Drug delivery scientists are especially enthusiastic about possible utility of dendrimers as drug delivery tool. Dendrimers like poly L lysine (PLL), poly-propylene imine (PPI) and poly-amidoamine (PAMAM), etc., are used as gene carrier in drug delivery system because of their chemical characteristics. These characteristics of chemical compounds are analysed using topological indices (invariants under graph isomorphism) such as Wiener index, Zagreb index, etc., Prof. V. R. Kulli motivated by the application of Zagreb indices in finding the total π energy and derived Gourava indices which is an improved version over Zagreb indices. In this paper, we study the structure of PLL-Dendrimer that has the following applications: reduction in toxicity, colon delivery, and topical delivery. Also, we determine first and second Gourava indices, first and second hyper Gourava indices, product and sum connectivity Gourava indices for PLL-Dendrimer. Gourava Indices have found applications in Quantitative Structure-Property Relationship (QSPR)/ Quantitative Structure-Activity Relationship (QSAR) studies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=connectivity%20Gourava%20indices" title="connectivity Gourava indices">connectivity Gourava indices</a>, <a href="https://publications.waset.org/abstracts/search?q=dendrimer" title=" dendrimer"> dendrimer</a>, <a href="https://publications.waset.org/abstracts/search?q=Gourava%20indices" title=" Gourava indices"> Gourava indices</a>, <a href="https://publications.waset.org/abstracts/search?q=hyper%20GouravaG%20indices" title=" hyper GouravaG indices"> hyper GouravaG indices</a> </p> <a href="https://publications.waset.org/abstracts/110831/a-study-on-the-computation-of-gourava-indices-for-poly-l-lysine-dendrimer-and-its-biomedical-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/110831.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">138</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18895</span> Tunable Control of Therapeutics Release from the Nanochannel Delivery System (nDS) </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Thomas%20Geninatti">Thomas Geninatti</a>, <a href="https://publications.waset.org/abstracts/search?q=Bruno%20Giacomo"> Bruno Giacomo</a>, <a href="https://publications.waset.org/abstracts/search?q=Alessandro%20Grattoni"> Alessandro Grattoni</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nanofluidic devices have been investigated for over a decade as promising platforms for the controlled release of therapeutics. The nanochannel drug delivery system (nDS), a membrane fabricated with high precision silicon techniques, capable of zero-order release of drugs by exploiting diffusion transport at the nanoscale originated from the interactions between molecules with nanochannel surfaces, showed the flexibility of the sustained release in vitro and in vivo, over periods of time ranging from weeks to months. To improve the implantable bio nanotechnology, in order to create a system that possesses the key features for achieve the suitable release of therapeutics, the next generation of nDS has been created. Platinum electrodes are integrated by e-beam deposition onto both surfaces of the membrane allowing low voltage (<2 V) and active temporal control of drug release through modulation of electrostatic potentials at the inlet and outlet of the membrane’s fluidic channels. Hence, a tunable administration of drugs is ensured from the nanochannel drug delivery system. The membrane will be incorporated into a peek implantable capsule, which will include drug reservoir, control hardware and RF system to allow suitable therapeutic regimens in real-time. Therefore, this new nanotechnology offers tremendous potential solutions to manage chronic disease such as cancer, heart disease, circadian dysfunction, pain and stress. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanochannel%20membrane" title="nanochannel membrane">nanochannel membrane</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20delivery" title=" drug delivery"> drug delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=tunable%20release" title=" tunable release"> tunable release</a>, <a href="https://publications.waset.org/abstracts/search?q=personalized%20administration" title=" personalized administration"> personalized administration</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoscale%20transport" title=" nanoscale transport"> nanoscale transport</a>, <a href="https://publications.waset.org/abstracts/search?q=biomems" title=" biomems"> biomems</a> </p> <a href="https://publications.waset.org/abstracts/15827/tunable-control-of-therapeutics-release-from-the-nanochannel-delivery-system-nds" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/15827.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">315</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18894</span> Prison Reforms: An Overview of the Nigerian Prisons as a Key Component of an Efficient Criminal Justice Delivery System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Foluke%20Dada">Foluke Dada</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Prisons all over the world are set up by law to provide restraint and custody for individuals accused or convicted of crimes by the state. The Nigerian prison dates back to the colonial era and is modelled after the British system. It is a system that lays emphasis on punishment and deterrence. It emphasises retribution rather than reformation. These, it can be argued, results in the inhuman conditions of Nigerian prisons and the conscienceless treatment of convicts and awaiting trial inmates in Nigerian prisons. This paper attempts an examination of the challenges currently beguiling Nigerian prisons, the need for reforms in the prison systems and the imperative of these reforms to an efficient criminal justice delivery system in the country. This paper further postulates that rehabilitation should be favoured as against retribution f the development of the Nigerian criminal justice system in line with the shift towards reform. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=criminal%20justice" title="criminal justice">criminal justice</a>, <a href="https://publications.waset.org/abstracts/search?q=human%20rights" title=" human rights"> human rights</a>, <a href="https://publications.waset.org/abstracts/search?q=prison%20reforms" title=" prison reforms"> prison reforms</a>, <a href="https://publications.waset.org/abstracts/search?q=rehabilitation%20and%20retribution" title=" rehabilitation and retribution"> rehabilitation and retribution</a> </p> <a href="https://publications.waset.org/abstracts/30000/prison-reforms-an-overview-of-the-nigerian-prisons-as-a-key-component-of-an-efficient-criminal-justice-delivery-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30000.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">669</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18893</span> The Application of Lean-Kaizen in Course Plan and Delivery in Malaysian Higher Education Sector</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nur%20Aishah%20Binti%20Awi">Nur Aishah Binti Awi</a>, <a href="https://publications.waset.org/abstracts/search?q=Zulfiqar%20Khan"> Zulfiqar Khan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Lean-kaizen has always been applied in manufacturing sector since many years ago. What about education sector? This paper discuss on how lean-kaizen can also be applied in education sector, specifically in academic area of Malaysian’s higher education sector. The purpose of this paper is to describe the application of lean kaizen in course plan and delivery. Lean-kaizen techniques have been used to identify waste in the course plan and delivery. A field study has been conducted to obtain the data. This study used both quantitative and qualitative data. The researcher had interviewed the chosen lecturers regarding to the problems of course plan and delivery that they encountered. Secondary data of students’ feedback at the end of semester also has been used to improve course plan and delivery. The result empirically shows that lean-kaizen helps to improve the course plan and delivery by reducing the wastes. Thus, this study demonstrates that lean-kaizen can also help education sector to improve their services as achieved by manufacturing sector. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=course%20delivery" title="course delivery">course delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=education" title=" education"> education</a>, <a href="https://publications.waset.org/abstracts/search?q=Kaizen" title=" Kaizen"> Kaizen</a>, <a href="https://publications.waset.org/abstracts/search?q=lean" title=" lean"> lean</a> </p> <a href="https://publications.waset.org/abstracts/25287/the-application-of-lean-kaizen-in-course-plan-and-delivery-in-malaysian-higher-education-sector" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25287.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">368</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18892</span> Design, Development and Characterization of Pioglitazone Transdermal Drug Delivery System</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dwarakanadha%20Reddy%20Peram">Dwarakanadha Reddy Peram</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Swarnalatha"> D. Swarnalatha</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Gopinath"> C. Gopinath</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The main aim of this research work was to design and development characterization of Pioglitazone transdermal drug delivery system by using various polymers such as Olibanum with different concentration by solvent evaporation technique. The prepared formulations were evaluated for different physicochemical characteristics like thickness, folding endurance, drug content, percentage moisture absorption, percentage moisture loss, percentage elongation break test and weight uniformity. The diffusion studies were performed by using modified Franz diffusion cells. The result of dissolution studies shows that formulation, F3 (Olibanum with 50 mg) showed maximum release of 99.95 % in 12hrs, whereas F1 (Olibanum and EC backing membrane) showed minimum release of 93.65% in 12 hr. Based on the drug release and physicochemical values obtained the formulation F3 is considered as an optimized formulation which shows higher percentage of drug release of 99.95 % in 12 hr. The developed transdermal patches increase the therapeutic efficacy and reduced toxic effect of pioglitazone. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pioglitazone" title="pioglitazone">pioglitazone</a>, <a href="https://publications.waset.org/abstracts/search?q=olibanum" title=" olibanum"> olibanum</a>, <a href="https://publications.waset.org/abstracts/search?q=transdermal%20drug%20delivery%20system" title=" transdermal drug delivery system"> transdermal drug delivery system</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20release%20percantage" title=" drug release percantage"> drug release percantage</a> </p> <a href="https://publications.waset.org/abstracts/85414/design-development-and-characterization-of-pioglitazone-transdermal-drug-delivery-system" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85414.pdf" target="_blank" class="btn btn-primary 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